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PKKYGVKEKDQVVAHILNLLLTGKLRSGDRVDRNEIAHGLGVSRVPIQEALVQLEHDGIVSTRYHRGAFI ERFDVATILEHHELDGLLNGIASARAAANPTPRILGQLDAVMRSLRNSKESRAFAECVWEYRRTVNDEYA GPRLHATIRASQNLIPRVFWMTYQNSRDDVLPFYEEENAAIHRREPEAARAACIGRSELMAQTMLAELFR RRVLVPPEGACPGPFGAPIPGFARSYQPSSPVP*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. tuberculosis H37Rv | Rv0043c | - | - | 100% (244) | PROBABLE TRANSCRIPTIONAL REGULATORY PROTEIN (PROBABLY GNTR-FAMILY) |
| M. tuberculosis H37Rv | Rv0165c | - | 2e-08 | 27.69% (130) | GntR family transcriptional regulator |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0044c | - | 1e-141 | 100.00% (244) | GntR family transcriptional regulator |
| M. gilvum PYR-GCK | Mflv_0859 | - | 9e-73 | 60.93% (215) | regulatory protein GntR, HTH |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_4571 | - | 4e-09 | 32.86% (140) | GntR family transcriptional regulatory protein |
| M. marinum M | MMAR_0062 | - | 1e-99 | 77.93% (222) | GntR family transcriptional regulator |
| M. avium 104 | MAV_0060 | - | 1e-103 | 81.45% (221) | transcriptional regulator, GntR family protein |
| M. smegmatis MC2 155 | MSMEG_6908 | - | 7e-78 | 63.55% (214) | putative HTH-type transcriptional regulator |
| M. thermoresistible (build 8) | TH_0516 | - | 1e-74 | 60.09% (223) | PROBABLE TRANSCRIPTIONAL REGULATORY PROTEIN (PROBABLY |
| M. ulcerans Agy99 | MUL_0061 | - | 3e-99 | 77.48% (222) | GntR family transcriptional regulator |
| M. vanbaalenii PYR-1 | Mvan_6046 | - | 7e-75 | 60.27% (219) | regulatory protein GntR, HTH |
CLUSTAL 2.0.9 multiple sequence alignment
Rv0043c|M.tuberculosis_H37Rv ----MPKKYGVKE---KDQVVAHILNLLLTGKLRSGDRVDRNEIAHGLGV
Mb0044c|M.bovis_AF2122/97 ----MPKKYGVKE---KDQVVAHILNLLLTGKLRSGDRVDRNEIAHGLGV
MAV_0060|M.avium_104 ----MPKKYGVKE---KDLVVSHILHLLLTGKLRTGDRVDRNEIAVGLGV
MMAR_0062|M.marinum_M ----MPKKYGVKE---KDQVVAHLLNLILTGKLRSGDRVDRNEIAGSLGV
MUL_0061|M.ulcerans_Agy99 ----MPKKCGVKE---KDQVVAHLLNLILTGKLRSGDRVDRNEIAGGLGV
MSMEG_6908|M.smegmatis_MC2_155 ----MPKKYGVKE---KDQVVSHIINLMMTGKLRTGDRIDRNEIVRDLGL
Mflv_0859|M.gilvum_PYR-GCK ----MPKKYGVKE---KDLVVTHVVNMVLTGRLRSGDRLDRNEIASELGL
Mvan_6046|M.vanbaalenii_PYR-1 ----MPKKYGVKE---KDLVVSHVVEMVLTGRLRSGDRLDRNEIAHDLGL
TH_0516|M.thermoresistible__bu -VAAMPKKYGVKE---KDLVVSHVVNLVLTGKLRSGDRLDRNEIARELGL
MAB_4571|M.abscessus_ATCC_1997 MNAPRARTREIRRPQLSEEVAGRLRAAIMTGDLRPGEYIRMDETAAQLGV
.:. ::. .: *. :: ::** **.*: : :* . **:
Rv0043c|M.tuberculosis_H37Rv SRVPIQEALVQLEHDGIVSTRYHRGAFIERFDVATILEHHELDGLLNGIA
Mb0044c|M.bovis_AF2122/97 SRVPIQEALVQLEHDGIVSTRYHRGAFIERFDVATILEHHELDGLLNGIA
MAV_0060|M.avium_104 SRVPIQEALVQLEHDGIVSTRYHRGAFVERFDEATVLEHHELDGLLNGIA
MMAR_0062|M.marinum_M SRVPIQEALVQLEHDGIVSTRYHRGAFVERFDQSTVLEHYELEGVLNGMA
MUL_0061|M.ulcerans_Agy99 SRVPIQEALVQLEHDGVVSTRYHRGAFVERFDQSTVLEHYELEGVLNGMA
MSMEG_6908|M.smegmatis_MC2_155 SRVPIQEAVVQLEHDGILSTRYHRGAFVARFDEATVAEHHELYGILNGIS
Mflv_0859|M.gilvum_PYR-GCK SRVPVQEAVVQLEHDGILSTRYHRGAFVERFDESTVREHHELYGVLCGLA
Mvan_6046|M.vanbaalenii_PYR-1 SRVPVQEAVVQLEHDGIVSTRYHRGAYVERFDESTVREHHELYGLLSGIA
TH_0516|M.thermoresistible__bu SRVPIQEAVVQLEHDGLLSTRYHRGAYIERFDESVILEHHEVYGVLNGMA
MAB_4571|M.abscessus_ATCC_1997 SVTPVREALLTLRGEGMVDAVPHRGYAVAALSRKDVEDIFALQSHLAVEL
* .*::**:: *. :*::.: *** : :. : : . : . *
Rv0043c|M.tuberculosis_H37Rv SARAAANPTPRILGQLDAVMRSLRNSKESRAFAECVWEYRRTVNDEYAGP
Mb0044c|M.bovis_AF2122/97 SARAAANPTPRILGQLDAVMRSLRNSKESRAFAECVWEYRRTVNDEYAGP
MAV_0060|M.avium_104 SARAATSPTPRILGELDTLLRSLRTAKDSRAFTDIAAQYRRTVNDEYAGP
MMAR_0062|M.marinum_M SARTAANPTPRILGELDGLMRTLRAAKDARIFAELTSEYRRTINEEYAGP
MUL_0061|M.ulcerans_Agy99 SARTAANPTPRILGELDGLMRTLRAAKDARIFAELASEYRRTINEEYAGP
MSMEG_6908|M.smegmatis_MC2_155 SARCAANPTPRILAQLEESLRIMHAAKDVKTFQDNCWVFRNTINDEYAGP
Mflv_0859|M.gilvum_PYR-GCK SGRAATASEPTVLADLEAATAQMRSGRDSRQFDSHARRFRSIINGEYAGP
Mvan_6046|M.vanbaalenii_PYR-1 SARAAAASDPAVVDTLDGELTQMRGARDSRQFDNHADRFRTTINEQYAGP
TH_0516|M.thermoresistible__bu SARAAADPSRRIVDRLEAVARIMANSRGTRKFLDAAGQYRQLINDEYAGP
MAB_4571|M.abscessus_ATCC_1997 AKAAAARITPEQADALAELNDALRNATSPDQVIWAEFEFHRLLNHVADRP
: *: * : . . :: :* *
Rv0043c|M.tuberculosis_H37Rv RLHATIRASQNLIPRVFWMTYQNSRDDVLPFYEEENAAIHRREPEAARAA
Mb0044c|M.bovis_AF2122/97 RLHATIRASQNLIPRVFWMTYQNSRDDVLPFYEEENAAIHRREPEAARAA
MAV_0060|M.avium_104 RLHATIRASQNLIPRLFWTTYQGGRDDLLPFYEDETSAIHRRDPEAARAA
MMAR_0062|M.marinum_M RLQALIRASQNLIPGAFWASYQYRREDMLPFYEDEHSAIHRRDPQAARAA
MUL_0061|M.ulcerans_Agy99 RLQALIRASQNLIPGAFWASYQYRREDMLPFYEDEHSAIHRRDPQAARAA
MSMEG_6908|M.smegmatis_MC2_155 RLQATIRAGESFAPSDFWTGYTPSKTEFLPTYDDEFAAIRDRDPENARKA
Mflv_0859|M.gilvum_PYR-GCK RLQAAIDASQTLIPHAFWQSYLQHRDQLLPFYESELTAIRDRDPDAARAA
Mvan_6046|M.vanbaalenii_PYR-1 RLQAAVNSSRTFIPRAFWQTYPQHRDRLLPSYEAELAAVRAGEPDAARAA
TH_0516|M.thermoresistible__bu RLRAAIRAAQTFLPRKFWLTCLQDHDEIWQTYDAETTAIRTGDPEGARSA
MAB_4571|M.abscessus_ATCC_1997 KLAWFLLQAVRYTPHQLFAEDASWIVPTTETHDKLIAALRAGDIAEVIAQ
:* : . * :: :: :*:: : .
Rv0043c|M.tuberculosis_H37Rv CIGRSELMAQTMLAELFRRRVLVPPEGACPG---PFGAPIPGFARSYQPS
Mb0044c|M.bovis_AF2122/97 CIGRSELMAQTMLAELFRRRVLVPPEGACPG---PFGAPIPGFARSYQPS
MAV_0060|M.avium_104 CVERSYRMAQTMLGELFRRRVFTPPDDAGR----VVAGPLPVLADADTIC
MMAR_0062|M.marinum_M CSGRSELMAQSMLAELFRRQVFTPHEQACRHNGHATAAPVAPLPARPKIV
MUL_0061|M.ulcerans_Agy99 CSGRSELMAQAMLAELFRRQVFTPHEQACRNNGHATAAPVAPLPSRPKIV
MSMEG_6908|M.smegmatis_MC2_155 CMHRSEIMSRIMIAELTRRGVFG-----------ELRSP-----------
Mflv_0859|M.gilvum_PYR-GCK CAQRSDVMACALLTELVRRGVLRR--------------------------
Mvan_6046|M.vanbaalenii_PYR-1 CAQRAEVMASILLTELVRRGVLRAPQSQ----------------------
TH_0516|M.thermoresistible__bu CARRSATMGRLMCNELVRRGVLEPTGTVAPTR------------------
MAB_4571|M.abscessus_ATCC_1997 TEVQFIDGARRLIEYLDRTGMWSQD-------------------------
: . : * * :
Rv0043c|M.tuberculosis_H37Rv SPVP-------
Mb0044c|M.bovis_AF2122/97 SPVP-------
MAV_0060|M.avium_104 GGASLAL----
MMAR_0062|M.marinum_M VETPEATRLAF
MUL_0061|M.ulcerans_Agy99 VETPEATRLAF
MSMEG_6908|M.smegmatis_MC2_155 -----------
Mflv_0859|M.gilvum_PYR-GCK -----------
Mvan_6046|M.vanbaalenii_PYR-1 -----------
TH_0516|M.thermoresistible__bu -----------
MAB_4571|M.abscessus_ATCC_1997 -----------