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PKKCGVKEKDQVVAHLLNLILTGKLRSGDRVDRNEIAGGLGVSRVPIQEALVQLEHDGVVSTRYHRGAFV ERFDQSTVLEHYELEGVLNGMASARTAANPTPRILGELDGLMRTLRAAKDARIFAELASEYRRTINEEYA GPRLQALIRASQNLIPGAFWASYQYRREDMLPFYEDEHSAIHRRDPQAARAACSGRSELMAQAMLAELFR RQVFTPHEQACRNNGHATAAPVAPLPSRPKIVVETPEATRLAF*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. ulcerans Agy99 | MUL_0061 | - | - | 100% (254) | GntR family transcriptional regulator |
| M. ulcerans Agy99 | MUL_1058 | - | 4e-12 | 25.82% (182) | GntR family transcriptional regulator |
| M. ulcerans Agy99 | MUL_3894 | - | 8e-12 | 25.60% (207) | GntR family transcriptional regulator |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0044c | - | 4e-99 | 77.48% (222) | GntR family transcriptional regulator |
| M. gilvum PYR-GCK | Mflv_0859 | - | 3e-73 | 63.08% (214) | regulatory protein GntR, HTH |
| M. tuberculosis H37Rv | Rv0043c | - | 4e-99 | 77.48% (222) | GntR family transcriptional regulator |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_4571 | - | 9e-11 | 30.32% (155) | GntR family transcriptional regulatory protein |
| M. marinum M | MMAR_0062 | - | 1e-140 | 97.24% (254) | GntR family transcriptional regulator |
| M. avium 104 | MAV_0060 | - | 3e-96 | 72.88% (236) | transcriptional regulator, GntR family protein |
| M. smegmatis MC2 155 | MSMEG_6908 | - | 9e-76 | 61.86% (215) | putative HTH-type transcriptional regulator |
| M. thermoresistible (build 8) | TH_0516 | - | 2e-68 | 57.14% (217) | PROBABLE TRANSCRIPTIONAL REGULATORY PROTEIN (PROBABLY |
| M. vanbaalenii PYR-1 | Mvan_6046 | - | 3e-71 | 59.81% (214) | regulatory protein GntR, HTH |
CLUSTAL 2.0.9 multiple sequence alignment
MUL_0061|M.ulcerans_Agy99 ----MPKKCGVKE---KDQVVAHLLNLILTGKLRSGDRVDRNEIAGGLGV
MMAR_0062|M.marinum_M ----MPKKYGVKE---KDQVVAHLLNLILTGKLRSGDRVDRNEIAGSLGV
Mb0044c|M.bovis_AF2122/97 ----MPKKYGVKE---KDQVVAHILNLLLTGKLRSGDRVDRNEIAHGLGV
Rv0043c|M.tuberculosis_H37Rv ----MPKKYGVKE---KDQVVAHILNLLLTGKLRSGDRVDRNEIAHGLGV
MAV_0060|M.avium_104 ----MPKKYGVKE---KDLVVSHILHLLLTGKLRTGDRVDRNEIAVGLGV
MSMEG_6908|M.smegmatis_MC2_155 ----MPKKYGVKE---KDQVVSHIINLMMTGKLRTGDRIDRNEIVRDLGL
Mflv_0859|M.gilvum_PYR-GCK ----MPKKYGVKE---KDLVVTHVVNMVLTGRLRSGDRLDRNEIASELGL
Mvan_6046|M.vanbaalenii_PYR-1 ----MPKKYGVKE---KDLVVSHVVEMVLTGRLRSGDRLDRNEIAHDLGL
TH_0516|M.thermoresistible__bu -VAAMPKKYGVKE---KDLVVSHVVNLVLTGKLRSGDRLDRNEIARELGL
MAB_4571|M.abscessus_ATCC_1997 MNAPRARTREIRRPQLSEEVAGRLRAAIMTGDLRPGEYIRMDETAAQLGV
.:. ::. .: *. :: ::** **.*: : :* . **:
MUL_0061|M.ulcerans_Agy99 SRVPIQEALVQLEHDGVVSTRYHRGAFVERFDQSTVLEHYELEGVLNGMA
MMAR_0062|M.marinum_M SRVPIQEALVQLEHDGIVSTRYHRGAFVERFDQSTVLEHYELEGVLNGMA
Mb0044c|M.bovis_AF2122/97 SRVPIQEALVQLEHDGIVSTRYHRGAFIERFDVATILEHHELDGLLNGIA
Rv0043c|M.tuberculosis_H37Rv SRVPIQEALVQLEHDGIVSTRYHRGAFIERFDVATILEHHELDGLLNGIA
MAV_0060|M.avium_104 SRVPIQEALVQLEHDGIVSTRYHRGAFVERFDEATVLEHHELDGLLNGIA
MSMEG_6908|M.smegmatis_MC2_155 SRVPIQEAVVQLEHDGILSTRYHRGAFVARFDEATVAEHHELYGILNGIS
Mflv_0859|M.gilvum_PYR-GCK SRVPVQEAVVQLEHDGILSTRYHRGAFVERFDESTVREHHELYGVLCGLA
Mvan_6046|M.vanbaalenii_PYR-1 SRVPVQEAVVQLEHDGIVSTRYHRGAYVERFDESTVREHHELYGLLSGIA
TH_0516|M.thermoresistible__bu SRVPIQEAVVQLEHDGLLSTRYHRGAYIERFDESVILEHHEVYGVLNGMA
MAB_4571|M.abscessus_ATCC_1997 SVTPVREALLTLRGEGMVDAVPHRGYAVAALSRKDVEDIFALQSHLAVEL
* .*::**:: *. :*::.: *** : :. : : . : . *
MUL_0061|M.ulcerans_Agy99 SARTAANPTPRILGELDGLMRTLRAAKDARIFAELASEYRRTINEEYAGP
MMAR_0062|M.marinum_M SARTAANPTPRILGELDGLMRTLRAAKDARIFAELTSEYRRTINEEYAGP
Mb0044c|M.bovis_AF2122/97 SARAAANPTPRILGQLDAVMRSLRNSKESRAFAECVWEYRRTVNDEYAGP
Rv0043c|M.tuberculosis_H37Rv SARAAANPTPRILGQLDAVMRSLRNSKESRAFAECVWEYRRTVNDEYAGP
MAV_0060|M.avium_104 SARAATSPTPRILGELDTLLRSLRTAKDSRAFTDIAAQYRRTVNDEYAGP
MSMEG_6908|M.smegmatis_MC2_155 SARCAANPTPRILAQLEESLRIMHAAKDVKTFQDNCWVFRNTINDEYAGP
Mflv_0859|M.gilvum_PYR-GCK SGRAATASEPTVLADLEAATAQMRSGRDSRQFDSHARRFRSIINGEYAGP
Mvan_6046|M.vanbaalenii_PYR-1 SARAAAASDPAVVDTLDGELTQMRGARDSRQFDNHADRFRTTINEQYAGP
TH_0516|M.thermoresistible__bu SARAAADPSRRIVDRLEAVARIMANSRGTRKFLDAAGQYRQLINDEYAGP
MAB_4571|M.abscessus_ATCC_1997 AKAAAARITPEQADALAELNDALRNATSPDQVIWAEFEFHRLLNHVADRP
: *: * : . . :: :* *
MUL_0061|M.ulcerans_Agy99 RLQALIRASQNLIPGAFWASYQYRREDMLPFYEDEHSAIHRRDPQAARAA
MMAR_0062|M.marinum_M RLQALIRASQNLIPGAFWASYQYRREDMLPFYEDEHSAIHRRDPQAARAA
Mb0044c|M.bovis_AF2122/97 RLHATIRASQNLIPRVFWMTYQNSRDDVLPFYEEENAAIHRREPEAARAA
Rv0043c|M.tuberculosis_H37Rv RLHATIRASQNLIPRVFWMTYQNSRDDVLPFYEEENAAIHRREPEAARAA
MAV_0060|M.avium_104 RLHATIRASQNLIPRLFWTTYQGGRDDLLPFYEDETSAIHRRDPEAARAA
MSMEG_6908|M.smegmatis_MC2_155 RLQATIRAGESFAPSDFWTGYTPSKTEFLPTYDDEFAAIRDRDPENARKA
Mflv_0859|M.gilvum_PYR-GCK RLQAAIDASQTLIPHAFWQSYLQHRDQLLPFYESELTAIRDRDPDAARAA
Mvan_6046|M.vanbaalenii_PYR-1 RLQAAVNSSRTFIPRAFWQTYPQHRDRLLPSYEAELAAVRAGEPDAARAA
TH_0516|M.thermoresistible__bu RLRAAIRAAQTFLPRKFWLTCLQDHDEIWQTYDAETTAIRTGDPEGARSA
MAB_4571|M.abscessus_ATCC_1997 KLAWFLLQAVRYTPHQLFAEDASWIVPTTETHDKLIAALRAGDIAEVIAQ
:* : . * :: :: :*:: : .
MUL_0061|M.ulcerans_Agy99 CSGRSELMAQAMLAELFRRQVFTPHEQACRNNGHATAAPVAPLPSRPKIV
MMAR_0062|M.marinum_M CSGRSELMAQSMLAELFRRQVFTPHEQACRHNGHATAAPVAPLPARPKIV
Mb0044c|M.bovis_AF2122/97 CIGRSELMAQTMLAELFRRRVLVPPEGACPG---PFGAPIPGFARSYQPS
Rv0043c|M.tuberculosis_H37Rv CIGRSELMAQTMLAELFRRRVLVPPEGACPG---PFGAPIPGFARSYQPS
MAV_0060|M.avium_104 CVERSYRMAQTMLGELFRRRVFTPPDDAGR----VVAGPLPVLADADTIC
MSMEG_6908|M.smegmatis_MC2_155 CMHRSEIMSRIMIAELTRRGVFG-----------ELRSP-----------
Mflv_0859|M.gilvum_PYR-GCK CAQRSDVMACALLTELVRRGVLRR--------------------------
Mvan_6046|M.vanbaalenii_PYR-1 CAQRAEVMASILLTELVRRGVLRAPQSQ----------------------
TH_0516|M.thermoresistible__bu CARRSATMGRLMCNELVRRGVLEPTGTVAPTR------------------
MAB_4571|M.abscessus_ATCC_1997 TEVQFIDGARRLIEYLDRTGMWSQD-------------------------
: . : * * :
MUL_0061|M.ulcerans_Agy99 VETPEATRLAF
MMAR_0062|M.marinum_M VETPEATRLAF
Mb0044c|M.bovis_AF2122/97 SPVP-------
Rv0043c|M.tuberculosis_H37Rv SPVP-------
MAV_0060|M.avium_104 GGASLAL----
MSMEG_6908|M.smegmatis_MC2_155 -----------
Mflv_0859|M.gilvum_PYR-GCK -----------
Mvan_6046|M.vanbaalenii_PYR-1 -----------
TH_0516|M.thermoresistible__bu -----------
MAB_4571|M.abscessus_ATCC_1997 -----------