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M. gilvum PYR-GCK Mflv_0803 (-)

annotation: type III restriction enzyme, res subunit
coordinates: 825137 - 828550
length: 1137

SNFAFLQAIGWPEMHADCRRAESYATSDPRSACFYSRRTVELLVDYLYGVLALPIPYKNDLAAKINDPKF
KSKVGVGIATKLNLIRKLGNTAVHDTQQIPQRAALDALRELHHVMLWAAFRYSTKPQAVPMKVLFDPKIA
AKAAPLSRQEVAELAAKFAAQDEAHVKTLADKDELAAQKDTEIAALREAVKQAQAANQQTDDRDYNEADT
RDRFVDVMLAEAGWGLTETKDREYPVTGMPNGDGKGFVDYVLWGEDGLPLAIVEAKRTTKSPQVGQQQAK
LYADCLEKMTGRRPVIFYTNGFEHWIWDDTGGYPPREIQGFYTRDQLELLIQRRGTRKPLTDMPIDSAIV
ERHYQHRAIRAIDDAFTAKEREALLVMATGSGKTRTVIALVKQLMEANWVKRVLFLADRTALVTQAANAF
KAHLPDATTVNLVTEKITDGRVYVCTYPTMMNLINDTDSGIRKFGPGYFDLVVIDEAHRSVYQKYRAIFD
WYDSLLVCLTATPKDEVDHNTYRLFHLEDGVPTDAYSLDDAVKEGFLVPAVGISVGTKFLRQGIRYADLS
EEEKDDWDALDWGDDDPPDEVSSEEINRFLFNEDTVDKVLAELMSKGHRVAEGDRLGKTIIFAKNQAHAE
FIARRFDVQYPQYAGTFARVITHSTAYAQSLIDNFSVTDKAPHIAISVDMLDTGIDVPDVVNLVFFKLVR
SKTKFWQMIGRGTRLRPDLLGPGKDKQNFYVFDFCGNLEFFSQDLPGSEGSFQKSLNQRLFEARLGLITA
IDHAWPPSEPEPEEGQGTETERGLRVDVAWSLHRSVAGMNLDNFLVRPHRRLVEQYSQWPAWTSLTPEVA
GDVAEHLAGLPSLHKDDDEDAKRFDMLVLRRQLAQLEGDAVAAERLREQIQNIATGLLSQTAIPSVKAQE
ALLDEVGGDEWWIDVTLPMLESVRRKLRGLLRFLEKAKRNQVYTDFADELSEASLVDLPGITPGTNWERF
QAKARAYLRRHQDHVALQRLRRNKPLTPDDLASLEQMLIESGTGEQADIELAKEQSHGLGLFVRSLVGLD
REAAAEAFGAYLDGTKFNADQIRFVNLIITELTANGFMEPVRLYESPYIDHAPTGPDDVFGDADVDTIVA
ILNSVRDNAAPKDGAA*
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. gilvum PYR-GCKMflv_0803--100% (1137)type III restriction enzyme, res subunit
M. gilvum PYR-GCKMflv_2408-2e-3227.14% (608) type III restriction enzyme, res subunit

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb2049c-4e-0522.22% (261) hypothetical protein Mb2049c
M. tuberculosis H37RvRv2024c-1e-0522.22% (261) hypothetical protein Rv2024c
M. leprae Br4923-----
M. abscessus ATCC 19977-----
M. marinum MMMAR_4272-9e-0527.19% (114) hypothetical protein MMAR_4272
M. avium 104MAV_5024-1e-4630.73% (537) type I restriction-modification system, R subunit
M. smegmatis MC2 155MSMEG_1238-9e-1324.49% (392) type III restriction enzyme, res subunit
M. thermoresistible (build 8)TH_4094-1e-1524.95% (469) PUTATIVE -
M. ulcerans Agy99-----
M. vanbaalenii PYR-1-----

CLUSTAL 2.0.9 multiple sequence alignment


Mb2049c|M.bovis_AF2122/97           --------------------------------------------------
Rv2024c|M.tuberculosis_H37Rv        --------------------------------------------------
MAV_5024|M.avium_104                --------------------------------------------------
Mflv_0803|M.gilvum_PYR-GCK          MSNFAFLQAIGWPEMHADCRRAESYATSDPRSACFYSRRTVELLVDYLYG
MSMEG_1238|M.smegmatis_MC2_155      --------------------------------------------------
TH_4094|M.thermoresistible__bu      VDAGLYESVITQRLQRQLETLRERSAQLTPQLTEVDEAEEALTLARHLMP
MMAR_4272|M.marinum_M               --------------------------------------------------
                                                                                      

Mb2049c|M.bovis_AF2122/97           --------------------------------------------------
Rv2024c|M.tuberculosis_H37Rv        --------------------------------------------------
MAV_5024|M.avium_104                --------------------------------------------------
Mflv_0803|M.gilvum_PYR-GCK          VLALPIPYKNDLAAKINDPKFKSKVGVGIATKLNLIRKLGNTAVHDTQQI
MSMEG_1238|M.smegmatis_MC2_155      --------------------------------------------------
TH_4094|M.thermoresistible__bu      VIERSLRCARGAEDRARLIEKLLAALGDPDALAEAVHQLDPGKIHRLDAV
MMAR_4272|M.marinum_M               --------------------------MEPRQDLESRSFAGTWRVYQQQAL
                                                                                      

Mb2049c|M.bovis_AF2122/97           --MGSVHDVIEAFRKAPSNAERGTKFEQLMVRYFELDPTMAQQYDAVWR-
Rv2024c|M.tuberculosis_H37Rv        --MGSVHDVIEAFRKAPSNAERGTKFEQLMVRYFELDPTMAQQYDAVWW-
MAV_5024|M.avium_104                --------------MLPKLKDAGWTEEQIIEQYRITDGRIVKVGSKHRR-
Mflv_0803|M.gilvum_PYR-GCK          PQRAALDALRELHHVMLWAAFRYSTKPQAVPMKVLFDPKIAAKAAPLSRQ
MSMEG_1238|M.smegmatis_MC2_155      -MVPGHEKWAERIAGGLAATKVVGTPIDNETRAMRLTQLLSRADDELLEE
TH_4094|M.thermoresistible__bu      TPVALGTTHIPRPTTPLSDAALMTNARDEPTLAAELRAELASADHVDLLC
MMAR_4272|M.marinum_M               DAFDADVAGGDNRCYLVLPPGAGKTMIGLEAARRLGRRTLVLVPNTAVQA
                                                            .              :          

Mb2049c|M.bovis_AF2122/97           -WIDWP------ERRGRTDTGIDLVARERD--------------------
Rv2024c|M.tuberculosis_H37Rv        -WIDWP------ERRGRTDTGIDLVARERD--------------------
MAV_5024|M.avium_104                -TAPLR------ADYVLEYEPGMPIGVVEA--------------------
Mflv_0803|M.gilvum_PYR-GCK          EVAELA------AKFAAQDEAHVKTLADKDELAAQKDTEIAALREAVKQA
MSMEG_1238|M.smegmatis_MC2_155      LVGGPV------VRLLESLDPTLSSPRRLR-------------------E
TH_4094|M.thermoresistible__bu      AFVKWHGLRLLERELTELKERGIPLRVITTTYMGATDARALDALVNEFGA
MMAR_4272|M.marinum_M               QWAATWDG-----RFPSTDPSAARCGTERDLAS----------------A
                                                                                      

Mb2049c|M.bovis_AF2122/97           -TGNYTAIQCKFYEPTHTLAKGDIDSFFTASGKTGFTNRVI---------
Rv2024c|M.tuberculosis_H37Rv        -TGNYTAIQCKFYEPTHTLAKGDIDSFFTASGKTGFTNRVI---------
MAV_5024|M.avium_104                -KREYSTPGKGMQQAKNYAQLLDVPFAYSTNGVSIVEDDRN---------
Mflv_0803|M.gilvum_PYR-GCK          QAANQQTDDRDYNEADTRDRFVDVMLAEAGWGLTETKDREYPVTGMPNGD
MSMEG_1238|M.smegmatis_MC2_155      LVEALHSPEELLRDRKVRQQLLDLLPIADATEVAGLLRLDT---------
TH_4094|M.thermoresistible__bu      EVRVNYETDRTRLHAKAWLLRRNTGFHTAYVGSSNLSHAALVDG------
MMAR_4272|M.marinum_M               MNVLTYQSLAVIDDETDSAVRREVLRSRDQQALLELLHPNG---------
                                                 .        :                           

Mb2049c|M.bovis_AF2122/97           ------------ISTTDRWGRNAEDALADQLVPVQRIGMAEIAESPIDWD
Rv2024c|M.tuberculosis_H37Rv        ------------ISTTDRWGRNAEDALADQLVPVQRIGMAEIAESPIDWD
MAV_5024|M.avium_104                ------------TGIER---ANLSTFPSPEMLWARYREWKGIKDDSAADG
Mflv_0803|M.gilvum_PYR-GCK          GKGFVDYVLWGEDGLPLAIVEAKRTTKSPQVGQQQAKLYADCLEKMTGRR
MSMEG_1238|M.smegmatis_MC2_155      ---------------------KRPYESLRAANFKRGSKAEKILFTYLGVD
TH_4094|M.thermoresistible__bu      -------LEWNVRLSAVSTPHLLEKFRATFDSYWENREFESYRPCEDGDK
MMAR_4272|M.marinum_M               --------RALIERAATLGPWTLVLDECHHLLATWGALVAALGSVLGPQT
                                                                                      

Mb2049c|M.bovis_AF2122/97           IAWPAG--------------------------------------DLQVNL
Rv2024c|M.tuberculosis_H37Rv        IAWPAD--------------------------------------DLQVNL
MAV_5024|M.avium_104                LLLPFN--------------------------------------RSLRNA
Mflv_0803|M.gilvum_PYR-GCK          PVIFYTNGFEHWIWDDTGGYPPREIQGFYTRDQLELLIQRRGTRKPLTDM
MSMEG_1238|M.smegmatis_MC2_155      TPQPPEE------------------------------------TSALPMV
TH_4094|M.thermoresistible__bu      LRNALDVASG------------------------------KKPRDPLRVT
MMAR_4272|M.marinum_M               ALIGLTATP-------------------------------VTDLTAWQHT
                                                                                      

Mb2049c|M.bovis_AF2122/97           TPAKRHELRPHQQQAIDAVFRG-FAVGNDRGKLIMACGTGKTFTALKIAE
Rv2024c|M.tuberculosis_H37Rv        TPAKRHELRPHQQQAIDAVFRG-FAVGNDRGKLIMACGTGKTFTALKIAE
MAV_5024|M.avium_104                DGTVK-EPRYYQRTAINRTVEA-ILAGDKRLLLTMATGTGKTFVSMQIVW
Mflv_0803|M.gilvum_PYR-GCK          PIDSAIVERHYQHRAIRAIDDA-FTAKEREALLVMATGSGKTRTVIALVK
MSMEG_1238|M.smegmatis_MC2_155      ESFAAYGLFSHQRDACKQSQNR-LRMNPHRVLLHMPTGSGKTRTAMHIIA
TH_4094|M.thermoresistible__bu      LSGLEVTAKPYQAELLEQLEAERVLHDRHRNLLVAATGTGKTVIAALDYR
MMAR_4272|M.marinum_M               LHDELFGTADFAVPTPALVKEG--DLAPYQELIYLTEPTPEEQAWVATHR
                                              .                  .  :  .  : :         

Mb2049c|M.bovis_AF2122/97           RIAAD---NGGSARILLLVPSISLLSQTLREWTAQSELDVRAFAVCSDTK
Rv2024c|M.tuberculosis_H37Rv        RIAAD---NGGSARILLLVPSISLLSQTLREWTAQSELDVRAFAVCSDTK
MAV_5024|M.avium_104                KLWNSQWVHGRHPRILYLADRNVLVDQPIEREFKPAFGAGEGSPIWKLKG
Mflv_0803|M.gilvum_PYR-GCK          QLMEAN----WVKRVLFLADRTALVTQAANAFKAHLPDATTVNLVTEKIT
MSMEG_1238|M.smegmatis_MC2_155      SELRQQ----EPTLVIWLAYSEELCEQAASEFEKAWHYLGDRELKTYRMW
TH_4094|M.thermoresistible__bu      RLVREVH--GRDLSLLFVAHRKEILQQARRMYQEVLTDPTFGELLVDGEQ
MMAR_4272|M.marinum_M               ARFAELMLALIDQQVGSMSLASWLRTRFVDRSTRDGNQIAWSTFERAEPD
                                                  :  :     :  :                       

Mb2049c|M.bovis_AF2122/97           VSRSAEDYHVHDVPIPVTTDA-----RVLLHEMAHRRCAQGLTVVFCTYQ
Rv2024c|M.tuberculosis_H37Rv        VSRSAEDYHVHDVPIPVTTDA-----RVLLHEMAHRRRAQGLTVVFCTYQ
MAV_5024|M.avium_104                TAKSGREIYFGLYQQLADGGD-----EPTGMFRQFARDFFDLVIVDECHR
Mflv_0803|M.gilvum_PYR-GCK          DGR----VYVCTYPTMMNLIN-----DTDSGIRKFGPGYFDLVVIDEAHR
MSMEG_1238|M.smegmatis_MC2_155      GSRDLDINDVRDGFMVAGLAKTFELMKRDPDFLARMADRVSLVIIDEAHQ
TH_4094|M.thermoresistible__bu      PAR-----WRHVFASIQSLNS--------ERLSTIDPEHFDVVVVDEFHH
MMAR_4272|M.marinum_M               LACSGLRFAYDGLIPLPDGAR----LREQHRVPPDAQDWVNVLTDFSVGH
                                     .                                      .:       :

Mb2049c|M.bovis_AF2122/97           SLPTVAKAQRLGVDEFDLVMCDEAHRTTGVTLAGDDESNVVRVHDGQYLK
Rv2024c|M.tuberculosis_H37Rv        SLPTVAKAQRLGVDEFDLVMCDEAHRTTGVTLAGDDESNFVRVHDGQYLK
MAV_5024|M.avium_104                GSARAESSWRKILDHFSPATQLGMTATPKRDETADTYAYFGGAPLFEYTL
Mflv_0803|M.gilvum_PYR-GCK          SVYQKYRAIFDWYDSLLVCLTATPKDEVDHN-TYRLFHLEDGVPTDAYSL
MSMEG_1238|M.smegmatis_MC2_155      AIAQTYRLVLEVLCDRNEETKLLGLTATPGRTWNDPDADRELANFFNRQK
TH_4094|M.thermoresistible__bu      AQAASYR---RLLDHIRPIELLGLTATPERGDGVDVRQFFGGRVAAELRL
MMAR_4272|M.marinum_M               LQQSNDPRDAQALAAIKRVLPGLGYRLTSRGVRVATSPVDRVCALSESKI
                                                                                      

Mb2049c|M.bovis_AF2122/97           AARRLYMTATPRIFTESIKDRADQHSAELVSMDDELTFGPEFHRLS-FGE
Rv2024c|M.tuberculosis_H37Rv        AARRLYMTATPRIFTESIKDRADQHSAELVSMDDELTFGPEFHRLS-FGE
MAV_5024|M.avium_104                AQGIEDGFLAP------------YRVRRVVLSPDAHGWAPEQGQLDLFGK
Mflv_0803|M.gilvum_PYR-GCK          DDAVKEGFLVPAVG----ISVGTKFLRQGIRYADLSEEEKDDWDALDWGD
MSMEG_1238|M.smegmatis_MC2_155      VTLSVRGYDSPVDY-----LIDEKYLARPVFQPLFYDSNQRELSASEIQR
TH_4094|M.thermoresistible__bu      WDALEQNLLCP--------------------FHYFGIYDGTDLEALQWKR
MMAR_4272|M.marinum_M               AATTHILDTEDAVLG------SGLRALVLCDFESMSGTLPTSLKGAPLSN
                                                                                      

Mb2049c|M.bovis_AF2122/97           AVERGLLTDYKVMVLTVDQGVIAPRLQQELSGVSGELMLDD--ASKIVGC
Rv2024c|M.tuberculosis_H37Rv        AVERGLLTDYKVMVLTVDQGVIAPRLQQELSGVSGELMLDD--ASKIVGC
MAV_5024|M.avium_104                EIPPGLYTTPDFERVVS----LLSRTEAAAKHLTNYLHATDRFAKTIVFC
Mflv_0803|M.gilvum_PYR-GCK          DDPPDEVSSEEINRFLFN-EDTVDKVLAELMSKGHRVAEGDRLGKTIIFA
MSMEG_1238|M.smegmatis_MC2_155      LANTLDIPDDILERLAVD----DQRNLAIISAIEGLVQKHS---RVIVFA
TH_4094|M.thermoresistible__bu      G----RYDLDELDRVYTG---NDARTRIILKEVRDKIADVG-AMRALGFC
MMAR_4272|M.marinum_M               QSGSAQLVTAMLAASDSR----RNSPLNALLVTGQTFACPAAIATQLVDF
                                               .                        .         :   

Mb2049c|M.bovis_AF2122/97           WNGLAKRSGTGIVAGEPPMRRAVAFAKDIKTSKQVAELFPKVVEAYRELV
Rv2024c|M.tuberculosis_H37Rv        WNGLAKRSGTGIVAGEPPMRRAVAFAKDIKTSKQVAELFPKVVEAYRELV
MAV_5024|M.avium_104                ANQEHADQMRRALHNANSDLTPQHRDYVVRIVSDEQEIGQGHLSRFCDTE
Mflv_0803|M.gilvum_PYR-GCK          KNQAHAEFIARRFD----VQYPQYAGTFARVITHSTAYAQSLIDNFSVTD
MSMEG_1238|M.smegmatis_MC2_155      ATVGHARMLAAVLR-------ARGILANSITSGTASAERSRIIAEFRDRS
TH_4094|M.thermoresistible__bu      VSVEHARYMAKRFV-------EAGIPARSVVGLDDSRERREALAALQSRE
MMAR_4272|M.marinum_M               CAERGLLVTAEPLD-------TQPALRTLRGGGTFTPRTWVALATEYFLA
                                                .                             :       

Mb2049c|M.bovis_AF2122/97           DDGPGLACSVRHVDGTFNALVRNEQLAWLKGVVAEDECRILSNARCLSEG
Rv2024c|M.tuberculosis_H37Rv        DDGPGLAC--------------------------------LNSSRRIQA-
MAV_5024|M.avium_104                AQFPVIAT----------------------------------TSEMLSTG
Mflv_0803|M.gilvum_PYR-GCK          KAPHIAIS-----------------------------------VDMLDTG
MSMEG_1238|M.smegmatis_MC2_155      DEPYVLCN-----------------------------------YGVLTTG
TH_4094|M.thermoresistible__bu      INALFTVD-------------------------------------LFNEG
MMAR_4272|M.marinum_M               GHSRVMIG----------------------------------TRALLGEG
                                                                                  :   

Mb2049c|M.bovis_AF2122/97           VDVPALDAVLFLNPRNSIVDVVQSVGRVMRKS-----PGKDYGYVILPVA
Rv2024c|M.tuberculosis_H37Rv        --------------------------------------------------
MAV_5024|M.avium_104                VDAPTVRNIVLFRPVGSMALFKQMIGRGTRLF-----PDEDKLSFEIIDY
Mflv_0803|M.gilvum_PYR-GCK          IDVPDVVNLVFFKLVRSKTKFWQMIGRGTRLRPDLLGPGKDKQNFYVFDF
MSMEG_1238|M.smegmatis_MC2_155      FDAPRTSAAVIARPTKSLVLYSQMVGRATRGT------------------
TH_4094|M.thermoresistible__bu      LDIPMVDTVLFLRPTESATVFLQQLGRGLRLAPG----KTVLTALDFVGH
MMAR_4272|M.marinum_M               WDCAAVNVNIDLTSATTQAAITQMRGRAIRKDPN--DAQKVANNWSVCCF
                                                                                      

Mb2049c|M.bovis_AF2122/97           VPEGVEPSA--ALADNKRFKVVWQVLNALRSHDERFDAMVNSIALNVKPT
Rv2024c|M.tuberculosis_H37Rv        --------------------------------------------------
MAV_5024|M.avium_104                SGASALFSD--PEFDGPPEHVIEEAINDE--GDVVEDVVVEEPEPSFEPT
Mflv_0803|M.gilvum_PYR-GCK          CGNLEFFSQDLPGSEGSFQKSLNQRLFEARLGLITAIDHAWPPSEPEPEE
MSMEG_1238|M.smegmatis_MC2_155      ------------RAGGNEVATIVTVVDQNLPGFGAMEDAFMNWEDVW---
TH_4094|M.thermoresistible__bu      HRREFRFDQRFRALTGLSRKRLEKQVQEGFPFLPSGSQIVLDEVAQKIVL
MMAR_4272|M.marinum_M               TTEHPRGDADYLRLVRKHDGYYAASPQGLIESGVTHCDPALSPYGPPAAD
                                                                                      

Mb2049c|M.bovis_AF2122/97           KTGEGSDKLLGGHIGPTSDEAGPAVAEQLAMFSLSQWQEAIYARIVDKVG
Rv2024c|M.tuberculosis_H37Rv        --------------------------------------------------
MAV_5024|M.avium_104                PRPADVDVDLD----------PEDLPAPRAKFYVDDVEVIVTAEAVYELD
Mflv_0803|M.gilvum_PYR-GCK          GQGTETERGLR-------VDVAWSLHRSVAGMNLDNFLVRPHRRLVEQYS
MSMEG_1238|M.smegmatis_MC2_155      --------------------------------------------------
TH_4094|M.thermoresistible__bu      ENVRQQVSPKK--------SVLVSEIRSHPDDRLASYLEESGRGLDDILR
MMAR_4272|M.marinum_M               AQAITARALQR----------ATQRAEARTWWRIGEPYEGVDVATIRVRA
                                                                                      

Mb2049c|M.bovis_AF2122/97           TRTYWEQWAADVADIAATLTTRIHALLGGADATAAAAFEQFLAGLRDNLN
Rv2024c|M.tuberculosis_H37Rv        --------------------------------------------------
MAV_5024|M.avium_104                PQTQQLRLVEYRDLVTETVRSLFPSAN----------------ELRAKWA
Mflv_0803|M.gilvum_PYR-GCK          QWPAWTSLTPEVAGDVAEHLAGLPSLHKDDDEDAKRFDMLVLRRQLAQLE
MSMEG_1238|M.smegmatis_MC2_155      --------------------------------------------------
TH_4094|M.thermoresistible__bu      PNRSWTTLCRDAGKLAEQPGPREAELVKRLKALAHVDDRKRADAYRRLLA
MMAR_4272|M.marinum_M               AHPFGVAAPRIAASALTPPVPGHPSPAR---------------FARGALA
                                                                                      

Mb2049c|M.bovis_AF2122/97           DSITPDDAISMLSQHLITKPVFDALFAGHDFASHNPVSR---AMQKMVDT
Rv2024c|M.tuberculosis_H37Rv        --------------------------------------------------
MAV_5024|M.avium_104                SRVSRREVLDALAEHGIDADELADRAGLPDADPIDVLVH---LAWNQPLA
Mflv_0803|M.gilvum_PYR-GCK          GDAVAAERLREQIQN--IATGLLSQTAIPSVKAQEALLD---EVGGDEWW
MSMEG_1238|M.smegmatis_MC2_155      --------------------------------------------------
TH_4094|M.thermoresistible__bu      SDVRSDSLAERRLADMLFYSLYPDGGGFEAAADGFDEVRREIVVAEMRQI
MMAR_4272|M.marinum_M               GVSAIGASAGAAVTAVNFGPLAGATTAGGIIAAGAALLAT--AAAAESRR
                                                                                      

Mb2049c|M.bovis_AF2122/97           VGGAG--LEAETARLEGFYESVRRRAGEVTSAEGKQQVIAELYEKFFRIG
Rv2024c|M.tuberculosis_H37Rv        --------------------------------------------------
MAV_5024|M.avium_104                TRTDR--VRRVRKEYSDFFEAFQP---------AAREVLEYLLDKYAEYG
Mflv_0803|M.gilvum_PYR-GCK          IDVTLPMLESVRRKLRGLLRFLEKAKRNQVYTDFADELSEASLVDLPGIT
MSMEG_1238|M.smegmatis_MC2_155      --------------------------------------------------
TH_4094|M.thermoresistible__bu      IDIAFDAAHRRTSELGEVIPELRDVPLALHATYSREEILAALGWVSPGRK
MMAR_4272|M.marinum_M               LAHAPNALEQLAAAVADGLNAAGGAERGSEALRITTDQDGWIRCELGDVP
                                                                                      

Mb2049c|M.bovis_AF2122/97           -FKKQAEALGIVYTPVEVVDFIVRAADFVSRKHFGRGLTDEGVHILDGFA
Rv2024c|M.tuberculosis_H37Rv        --------------------------------------------------
MAV_5024|M.avium_104                -ISELESPGVLQVPPLSSLGTPVEIARRFGSPEEWRAAQTRLGELVYVA-
Mflv_0803|M.gilvum_PYR-GCK          PGTNWERFQAKARAYLRRHQDHVALQRLRRNKPLTPDDLASLEQMLIESG
MSMEG_1238|M.smegmatis_MC2_155      --------------------------------------------------
TH_4094|M.thermoresistible__bu      PSTMREGVAWCPEVNADAFLITLKKSDTEYSPTTMYRDFALSPDLFHWES
MMAR_4272|M.marinum_M               TEQSRRFAEALDELLAPLTEPRYLIGRKILTPPVGRFARGIFAARAAMGL
                                                                                      

Mb2049c|M.bovis_AF2122/97           GTGTFITRLLQSDLITAADLTRKYSQELHANEIMLLAYYIAAVNIESTYH
Rv2024c|M.tuberculosis_H37Rv        --------------------------------------------------
MAV_5024|M.avium_104                --------------------------------------------------
Mflv_0803|M.gilvum_PYR-GCK          TGEQADIELAKEQSHGLGLFVRSLVGLDREAAAEAFGAYLDGTKFNADQI
MSMEG_1238|M.smegmatis_MC2_155      --------------------------------------------------
TH_4094|M.thermoresistible__bu      QSTTTASSPTGQRYIHHRERGSHVLLFVREAKKGAFGDGAPYIFLGPADY
MMAR_4272|M.marinum_M               PLPGAIAWHAVPRWFARRKDRRQSLAQSWRCHIGPPRQLSADSPEGQAIL
                                                                                      

Mb2049c|M.bovis_AF2122/97           ALAGKTADADAYEPFPGMALADTFQISEAGDSMDAIMFPYNNARILRQLA
Rv2024c|M.tuberculosis_H37Rv        --------------------------------------------------
MAV_5024|M.avium_104                --------------------------------------------------
Mflv_0803|M.gilvum_PYR-GCK          RFVNLIITELTANGFMEPVRLYESPYIDHAPTGPDDVFGDADVDTIVAIL
MSMEG_1238|M.smegmatis_MC2_155      --------------------------------------------------
TH_4094|M.thermoresistible__bu      VSHEGDRPMAITWRLRRPMPTEVYLGARAAVA------------------
MMAR_4272|M.marinum_M               DLFRGDNPLSVTTQLRTTWR------------------------------
                                                                                      

Mb2049c|M.bovis_AF2122/97           TPISVIIGNPPYSVGQSSANDLNANVKYPTLDGRIEQTYAKRSTAQLKNS
Rv2024c|M.tuberculosis_H37Rv        --------------------------------------------------
MAV_5024|M.avium_104                --------------------------------------------------
Mflv_0803|M.gilvum_PYR-GCK          NSVRDNAAPKDGAA------------------------------------
MSMEG_1238|M.smegmatis_MC2_155      --------------------------------------------------
TH_4094|M.thermoresistible__bu      --------------------------------------------------
MMAR_4272|M.marinum_M               --------------------------------------------------
                                                                                      

Mb2049c|M.bovis_AF2122/97           LYDSYIRAFRWATDRIGDNGVVGFVSNGGYIDGNTADGMRLSLADDYAAV
Rv2024c|M.tuberculosis_H37Rv        --------------------------------------------------
MAV_5024|M.avium_104                --------------------------------------------------
Mflv_0803|M.gilvum_PYR-GCK          --------------------------------------------------
MSMEG_1238|M.smegmatis_MC2_155      --------------------------------------------------
TH_4094|M.thermoresistible__bu      --------------------------------------------------
MMAR_4272|M.marinum_M               --------------------------------------------------
                                                                                      

Mb2049c|M.bovis_AF2122/97           YVYNLRGNQRTAGELSRQEGGKVFGGGSRNTVAIFLGIKDPKHSGPCDVL
Rv2024c|M.tuberculosis_H37Rv        --------------------------------------------------
MAV_5024|M.avium_104                --------------------------------------------------
Mflv_0803|M.gilvum_PYR-GCK          --------------------------------------------------
MSMEG_1238|M.smegmatis_MC2_155      --------------------------------------------------
TH_4094|M.thermoresistible__bu      --------------------------------------------------
MMAR_4272|M.marinum_M               --------------------------------------------------
                                                                                      

Mb2049c|M.bovis_AF2122/97           YRDIGDYLSREEKLRIVGDGYLDTVEWQTVTPNLHGDWVNQRDDAFSAWP
Rv2024c|M.tuberculosis_H37Rv        --------------------------------------------------
MAV_5024|M.avium_104                --------------------------------------------------
Mflv_0803|M.gilvum_PYR-GCK          --------------------------------------------------
MSMEG_1238|M.smegmatis_MC2_155      --------------------------------------------------
TH_4094|M.thermoresistible__bu      --------------------------------------------------
MMAR_4272|M.marinum_M               --------------------------------------------------
                                                                                      

Mb2049c|M.bovis_AF2122/97           VIGDKKAALDVTRVFANYSAGLKTSRDAWCYNFSRGALEANIGRTIDFYN
Rv2024c|M.tuberculosis_H37Rv        --------------------------------------------------
MAV_5024|M.avium_104                --------------------------------------------------
Mflv_0803|M.gilvum_PYR-GCK          --------------------------------------------------
MSMEG_1238|M.smegmatis_MC2_155      --------------------------------------------------
TH_4094|M.thermoresistible__bu      --------------------------------------------------
MMAR_4272|M.marinum_M               --------------------------------------------------
                                                                                      

Mb2049c|M.bovis_AF2122/97           SEVDRINEIRGRDAKTPPVDALITVDSAKFSWDRINKRQVAQGIRIEFAP
Rv2024c|M.tuberculosis_H37Rv        --------------------------------------------------
MAV_5024|M.avium_104                --------------------------------------------------
Mflv_0803|M.gilvum_PYR-GCK          --------------------------------------------------
MSMEG_1238|M.smegmatis_MC2_155      --------------------------------------------------
TH_4094|M.thermoresistible__bu      --------------------------------------------------
MMAR_4272|M.marinum_M               --------------------------------------------------
                                                                                      

Mb2049c|M.bovis_AF2122/97           AGMRLGTYRPFTKEHAYLDPNQQLNNCTYQLPSMFPTPEHGNVGYYVVGM
Rv2024c|M.tuberculosis_H37Rv        --------------------------------------------------
MAV_5024|M.avium_104                --------------------------------------------------
Mflv_0803|M.gilvum_PYR-GCK          --------------------------------------------------
MSMEG_1238|M.smegmatis_MC2_155      --------------------------------------------------
TH_4094|M.thermoresistible__bu      --------------------------------------------------
MMAR_4272|M.marinum_M               --------------------------------------------------
                                                                                      

Mb2049c|M.bovis_AF2122/97           GSDKPFSCLMLNAIPDLAFWGSSNGQFFPRWTYEKTEPRDGELDFESTTN
Rv2024c|M.tuberculosis_H37Rv        --------------------------------------------------
MAV_5024|M.avium_104                --------------------------------------------------
Mflv_0803|M.gilvum_PYR-GCK          --------------------------------------------------
MSMEG_1238|M.smegmatis_MC2_155      --------------------------------------------------
TH_4094|M.thermoresistible__bu      --------------------------------------------------
MMAR_4272|M.marinum_M               --------------------------------------------------
                                                                                      

Mb2049c|M.bovis_AF2122/97           AEVDDHGYRRVDNITGVILKLYRDTIGDQVTKDDIFYYVYGLLHDPAYRT
Rv2024c|M.tuberculosis_H37Rv        --------------------------------------------------
MAV_5024|M.avium_104                --------------------------------------------------
Mflv_0803|M.gilvum_PYR-GCK          --------------------------------------------------
MSMEG_1238|M.smegmatis_MC2_155      --------------------------------------------------
TH_4094|M.thermoresistible__bu      --------------------------------------------------
MMAR_4272|M.marinum_M               --------------------------------------------------
                                                                                      

Mb2049c|M.bovis_AF2122/97           KYAADLKKMLPHIPTPETRERFDQLASAGRKLADLHVGYESVKPYPLDVQ
Rv2024c|M.tuberculosis_H37Rv        --------------------------------------------------
MAV_5024|M.avium_104                --------------------------------------------------
Mflv_0803|M.gilvum_PYR-GCK          --------------------------------------------------
MSMEG_1238|M.smegmatis_MC2_155      --------------------------------------------------
TH_4094|M.thermoresistible__bu      --------------------------------------------------
MMAR_4272|M.marinum_M               --------------------------------------------------
                                                                                      

Mb2049c|M.bovis_AF2122/97           LKPGADPEDRETWRVEKMKWKSKQDHSTIIYNSRVTIAGIPDEAERYLLG
Rv2024c|M.tuberculosis_H37Rv        --------------------------------------------------
MAV_5024|M.avium_104                --------------------------------------------------
Mflv_0803|M.gilvum_PYR-GCK          --------------------------------------------------
MSMEG_1238|M.smegmatis_MC2_155      --------------------------------------------------
TH_4094|M.thermoresistible__bu      --------------------------------------------------
MMAR_4272|M.marinum_M               --------------------------------------------------
                                                                                      

Mb2049c|M.bovis_AF2122/97           SRSALGWIIDRYRVTTDKASGIVNDPNDWCDEHANPTYIVDLIKKVTTVS
Rv2024c|M.tuberculosis_H37Rv        --------------------------------------------------
MAV_5024|M.avium_104                --------------------------------------------------
Mflv_0803|M.gilvum_PYR-GCK          --------------------------------------------------
MSMEG_1238|M.smegmatis_MC2_155      --------------------------------------------------
TH_4094|M.thermoresistible__bu      --------------------------------------------------
MMAR_4272|M.marinum_M               --------------------------------------------------
                                                                                      

Mb2049c|M.bovis_AF2122/97           VETMKIVDSIVALASAGSDST
Rv2024c|M.tuberculosis_H37Rv        ---------------------
MAV_5024|M.avium_104                ---------------------
Mflv_0803|M.gilvum_PYR-GCK          ---------------------
MSMEG_1238|M.smegmatis_MC2_155      ---------------------
TH_4094|M.thermoresistible__bu      ---------------------
MMAR_4272|M.marinum_M               ---------------------