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M. tuberculosis H37Rv Rv2024c (-)

annotation: hypothetical protein Rv2024c
coordinates: 2268693 - 2270240
length: 515

GSVHDVIEAFRKAPSNAERGTKFEQLMVRYFELDPTMAQQYDAVWWWIDWPERRGRTDTGIDLVARERDT
GNYTAIQCKFYEPTHTLAKGDIDSFFTASGKTGFTNRVIISTTDRWGRNAEDALADQLVPVQRIGMAEIA
ESPIDWDIAWPADDLQVNLTPAKRHELRPHQQQAIDAVFRGFAVGNDRGKLIMACGTGKTFTALKIAERI
AADNGGSARILLLVPSISLLSQTLREWTAQSELDVRAFAVCSDTKVSRSAEDYHVHDVPIPVTTDARVLL
HEMAHRRRAQGLTVVFCTYQSLPTVAKAQRLGVDEFDLVMCDEAHRTTGVTLAGDDESNFVRVHDGQYLK
AARRLYMTATPRIFTESIKDRADQHSAELVSMDDELTFGPEFHRLSFGEAVERGLLTDYKVMVLTVDQGV
IAPRLQQELSGVSGELMLDDASKIVGCWNGLAKRSGTGIVAGEPPMRRAVAFAKDIKTSKQVAELFPKVV
EAYRELVDDGPGLACLNSSRRIQA*
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. tuberculosis H37RvRv2024c--100% (515)hypothetical protein Rv2024c
M. tuberculosis H37RvRv1179c-9e-0629.13% (127) hypothetical protein Rv1179c

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb2049c-0.099.21% (506) hypothetical protein Mb2049c
M. gilvum PYR-GCKMflv_2408-5e-0731.71% (164) type III restriction enzyme, res subunit
M. leprae Br4923-----
M. abscessus ATCC 19977-----
M. marinum M-----
M. avium 104-----
M. smegmatis MC2 155-----
M. thermoresistible (build 8)-----
M. ulcerans Agy99-----
M. vanbaalenii PYR-1-----

CLUSTAL 2.0.9 multiple sequence alignment


Rv2024c|M.tuberculosis_H37Rv      MGSVHDVIEAFRKAPSNAERGTKFEQL-MVRYFELDPTMAQQYDAVWWWI
Mb2049c|M.bovis_AF2122/97         MGSVHDVIEAFRKAPSNAERGTKFEQL-MVRYFELDPTMAQQYDAVWRWI
Mflv_2408|M.gilvum_PYR-GCK        MSDSDDDARLPAEARARKLIDSQLTQAGWVVQDKKDLNLFAAQGVAVREV
                                  *.. .*  .   :* :.   .::: *   *   : * .:    ...   :

Rv2024c|M.tuberculosis_H37Rv      DWPERRGRTD-------TGIDLVARERDTGNYTAIQCKFYEPTHTLAKGD
Mb2049c|M.bovis_AF2122/97         DWPERRGRTD-------TGIDLVARERDTGNYTAIQCKFYEPTHTLAKGD
Mflv_2408|M.gilvum_PYR-GCK        VMKPGHGRVDYLLYVDKAVVGVIEAKPVGTPLSGVEWQSAMYADGLPADV
                                       :**.*       : :.::  :      :.:: :    :. *. . 

Rv2024c|M.tuberculosis_H37Rv      IDSFFTASGKTGFTNRVIISTTDRWGRNAEDALADQLVPVQRIGMAEIAE
Mb2049c|M.bovis_AF2122/97         IDSFFTASGKTGFTNRVIISTTDRWGRNAEDALADQLVPVQRIGMAEIAE
Mflv_2408|M.gilvum_PYR-GCK        RIAAKTRDGRLPFVFEASGVETHFTNGFDPEPRARLIFNVPRPETMARHL
                                    :  * .*:  *. ..    *.  .    :. *  :. * *        

Rv2024c|M.tuberculosis_H37Rv      SPIDWDIAWPADDLQVNLTPAKR-HELRPHQQQAIDAVFRGFAVG-NDRG
Mb2049c|M.bovis_AF2122/97         SPIDWDIAWPAGDLQVNLTPAKR-HELRPHQQQAIDAVFRGFAVG-NDRG
Mflv_2408|M.gilvum_PYR-GCK        REAETNPDSPTWRAKVRKLPALDTEALRPAQIEAINGVEQSLADQRYDRS
                                     : :   *:   :*.  **   . *** * :**:.* :.:*    **.

Rv2024c|M.tuberculosis_H37Rv      KLIMACGTGKTFTALKIAERIAADNGGSARILLLVPSISLLSQTLREWT-
Mb2049c|M.bovis_AF2122/97         KLIMACGTGKTFTALKIAERIAADNGGSARILLLVPSISLLSQTLREWT-
Mflv_2408|M.gilvum_PYR-GCK        LVQMATGAGKTFTAVTQSYRLLK-HGGVDRVLFLVDRNNLADQTLGEFQN
                                   : ** *:******:. : *:   :**  *:*:**   .* .*** *:  

Rv2024c|M.tuberculosis_H37Rv      AQSELDVRAFAVCSDTKVSRSAEDYHVHDVPIPVTTDARVLLHEMAHRRR
Mb2049c|M.bovis_AF2122/97         AQSELDVRAFAVCSDTKVSRSAEDYHVHDVPIPVTTDARVLLHEMAHRRC
Mflv_2408|M.gilvum_PYR-GCK        YRTPDDGRRFTELYNVNKLSSAGLLGSTKVTISTIQRVFRFIKAGEVSDT
                                   ::  * * *:   :.:   **      .*.*..   .  :::       

Rv2024c|M.tuberculosis_H37Rv      AQGLTVVFCTYQSLPTVAKAQRLGVDEFDLVMCDEAHRTTGVTLAGDDES
Mb2049c|M.bovis_AF2122/97         AQGLTVVFCTYQSLPTVAKAQRLGVDEFDLVMCDEAHRTTGVTLAGDDES
Mflv_2408|M.gilvum_PYR-GCK        DD-PDIDDYIPDAPVTVSYSDALPPETFDLVIVDEAHRSIYGVWRG----
                                   :   :     ::  **: :: *  : ****: *****:   .  *    

Rv2024c|M.tuberculosis_H37Rv      NFVRVHDGQYLKAARRLYMTATPRIFTESIKDRADQHSAELVSMDDELTF
Mb2049c|M.bovis_AF2122/97         NVVRVHDGQYLKAARRLYMTATPRIFTESIKDRADQHSAELVSMDDELTF
Mflv_2408|M.gilvum_PYR-GCK        -VLEYFDAHVVGLTATPGKQTFAFFRQNLVSDYTYPESVADGVNVDFDVY
                                   .:. .*.: :  :      : . :  : :.* :  .*.      *  .:

Rv2024c|M.tuberculosis_H37Rv      GPEFHRLSFGEAVERGLLTDYKVMVLTVDQGVIAPRLQQELSGVSGELML
Mb2049c|M.bovis_AF2122/97         GPEFHRLSFGEAVERGLLTDYKVMVLTVDQGVIAPRLQQELSGVSGELML
Mflv_2408|M.gilvum_PYR-GCK        RIRTKISDQGSHIEAGTIVP-KVDRRTREQRLETLDDDLDYVPGQLDRAV
                                    . :  . *. :* * :.  **   * :* : :   : :    . :  :

Rv2024c|M.tuberculosis_H37Rv      DDASKIVGCWNGLAKRSGTGIVAGEPPMRRAVAFAKDIKTSKQVAELFPK
Mb2049c|M.bovis_AF2122/97         DDASKIVGCWNGLAKRSGTGIVAGEPPMRRAVAFAKDIKTSKQVAELFPK
Mflv_2408|M.gilvum_PYR-GCK        TATDQIRTVLESFRDRLFTEIFPGRSTVPKTLIFAKDDNHAEEIVKQVRE
                                    :.:*    :.: .*  * *..*...: ::: **** : ::::.: . :

Rv2024c|M.tuberculosis_H37Rv      VVEAYRELVDDGPGLAC--------------------------------L
Mb2049c|M.bovis_AF2122/97         VVEAYRELVDDGPGLACSVRHVDGTFNALVRNEQLAWLKGVVAEDECRIL
Mflv_2408|M.gilvum_PYR-GCK        VFGKGNDFAAKITYNARN---------------AKEQLKAFRTSPSLRIA
                                  *.   .::. . .  *                                  

Rv2024c|M.tuberculosis_H37Rv      NSSRRIQA------------------------------------------
Mb2049c|M.bovis_AF2122/97         SNARCLSEGVDVPALDAVLFLNPRNSIVDVVQSVGRVMRKSPGKDYGYVI
Mflv_2408|M.gilvum_PYR-GCK        VTVDMIATGTDVKPLECVFFMRDVRSAQYFEQMKGRGARTVPDADFQAVT
                                   .   :                                            

Rv2024c|M.tuberculosis_H37Rv      --------------------------------------------------
Mb2049c|M.bovis_AF2122/97         LPVAVPEGVEPSAALADNKRFKVVWQVLNALRSHDERFDAMVNSIALNVK
Mflv_2408|M.gilvum_PYR-GCK        P----------------DATSKTRFVIVDAIGVTEHEFVEPPLNRQRSVP
                                                                                    

Rv2024c|M.tuberculosis_H37Rv      --------------------------------------------------
Mb2049c|M.bovis_AF2122/97         PTKTGEGSDKLLGGHIGPTSDEAGPAVAEQLAMFSLSQWQEAIYARIVDK
Mflv_2408|M.gilvum_PYR-GCK        LKKLLEKAANLT------ITEDEAATLASRLAKLELDLTDAER--VELDE
                                                                                    

Rv2024c|M.tuberculosis_H37Rv      --------------------------------------------------
Mb2049c|M.bovis_AF2122/97         VGTRTYWEQWAADVADIAATLTTRIHALLGGADATAAAAFEQFLAGLRDN
Mflv_2408|M.gilvum_PYR-GCK        VAGQPVRDVIRSLVDAVEPSTTTPEAIEAALVPIASNPELRSRVLELRAA
                                                                                    

Rv2024c|M.tuberculosis_H37Rv      --------------------------------------------------
Mb2049c|M.bovis_AF2122/97         LNDSITPDDAISMLSQHLITKPVFDALFAGHDFASHNPVSRAMQKMVDTV
Mflv_2408|M.gilvum_PYR-GCK        HDRIIDEVSADELIEAGGVVDTGKARHIVESWTAYLDEHRDEITALQLGY
                                                                                    

Rv2024c|M.tuberculosis_H37Rv      --------------------------------------------------
Mb2049c|M.bovis_AF2122/97         GGAGLEAETARLEGFYESVRRRAGEVTSAEGKQQVIAELYEKFFRIGFKK
Mflv_2408|M.gilvum_PYR-GCK        EAGERRIDFAFIEGLATRIARPPHNWTPDVIWNAYAAIDGEKVHRSATHA
                                                                                    

Rv2024c|M.tuberculosis_H37Rv      --------------------------------------------------
Mb2049c|M.bovis_AF2122/97         QAEALGIVYTPVEVVDFIVRAADFVSRKHFGRGLTDEGVHILDGFAGTGT
Mflv_2408|M.gilvum_PYR-GCK        VTDLVSLVRYATGVDDELVPYGDRVREKYAAWLTQQE-------------
                                                                                    

Rv2024c|M.tuberculosis_H37Rv      --------------------------------------------------
Mb2049c|M.bovis_AF2122/97         FITRLLQSDLITAADLTRKYSQELHANEIMLLAYYIAAVNIESTYHALAG
Mflv_2408|M.gilvum_PYR-GCK        ------------QAGVTFTDTERWWLDRMVSVIASSAGIRVEDLDDAPFI
                                                                                    

Rv2024c|M.tuberculosis_H37Rv      --------------------------------------------------
Mb2049c|M.bovis_AF2122/97         KTADADAYEPFPGMALADTFQISEAGDSMDAIMFPYNNARILRQLATPIS
Mflv_2408|M.gilvum_PYR-GCK        ERGGTDG-------------AIRDLGDRAAELIDELNAELTA--------
                                                                                    

Rv2024c|M.tuberculosis_H37Rv      --------------------------------------------------
Mb2049c|M.bovis_AF2122/97         VIIGNPPYSVGQSSANDLNANVKYPTLDGRIEQTYAKRSTAQLKNSLYDS
Mflv_2408|M.gilvum_PYR-GCK        --------------------------------------------------
                                                                                    

Rv2024c|M.tuberculosis_H37Rv      --------------------------------------------------
Mb2049c|M.bovis_AF2122/97         YIRAFRWATDRIGDNGVVGFVSNGGYIDGNTADGMRLSLADDYAAVYVYN
Mflv_2408|M.gilvum_PYR-GCK        --------------------------------------------------
                                                                                    

Rv2024c|M.tuberculosis_H37Rv      --------------------------------------------------
Mb2049c|M.bovis_AF2122/97         LRGNQRTAGELSRQEGGKVFGGGSRNTVAIFLGIKDPKHSGPCDVLYRDI
Mflv_2408|M.gilvum_PYR-GCK        --------------------------------------------------
                                                                                    

Rv2024c|M.tuberculosis_H37Rv      --------------------------------------------------
Mb2049c|M.bovis_AF2122/97         GDYLSREEKLRIVGDGYLDTVEWQTVTPNLHGDWVNQRDDAFSAWPVIGD
Mflv_2408|M.gilvum_PYR-GCK        --------------------------------------------------
                                                                                    

Rv2024c|M.tuberculosis_H37Rv      --------------------------------------------------
Mb2049c|M.bovis_AF2122/97         KKAALDVTRVFANYSAGLKTSRDAWCYNFSRGALEANIGRTIDFYNSEVD
Mflv_2408|M.gilvum_PYR-GCK        --------------------------------------------------
                                                                                    

Rv2024c|M.tuberculosis_H37Rv      --------------------------------------------------
Mb2049c|M.bovis_AF2122/97         RINEIRGRDAKTPPVDALITVDSAKFSWDRINKRQVAQGIRIEFAPAGMR
Mflv_2408|M.gilvum_PYR-GCK        --------------------------------------------------
                                                                                    

Rv2024c|M.tuberculosis_H37Rv      --------------------------------------------------
Mb2049c|M.bovis_AF2122/97         LGTYRPFTKEHAYLDPNQQLNNCTYQLPSMFPTPEHGNVGYYVVGMGSDK
Mflv_2408|M.gilvum_PYR-GCK        --------------------------------------------------
                                                                                    

Rv2024c|M.tuberculosis_H37Rv      --------------------------------------------------
Mb2049c|M.bovis_AF2122/97         PFSCLMLNAIPDLAFWGSSNGQFFPRWTYEKTEPRDGELDFESTTNAEVD
Mflv_2408|M.gilvum_PYR-GCK        --------------------------------------------------
                                                                                    

Rv2024c|M.tuberculosis_H37Rv      --------------------------------------------------
Mb2049c|M.bovis_AF2122/97         DHGYRRVDNITGVILKLYRDTIGDQVTKDDIFYYVYGLLHDPAYRTKYAA
Mflv_2408|M.gilvum_PYR-GCK        --------------------------------------------------
                                                                                    

Rv2024c|M.tuberculosis_H37Rv      --------------------------------------------------
Mb2049c|M.bovis_AF2122/97         DLKKMLPHIPTPETRERFDQLASAGRKLADLHVGYESVKPYPLDVQLKPG
Mflv_2408|M.gilvum_PYR-GCK        --------------------------------------------------
                                                                                    

Rv2024c|M.tuberculosis_H37Rv      --------------------------------------------------
Mb2049c|M.bovis_AF2122/97         ADPEDRETWRVEKMKWKSKQDHSTIIYNSRVTIAGIPDEAERYLLGSRSA
Mflv_2408|M.gilvum_PYR-GCK        --------------------------------------------------
                                                                                    

Rv2024c|M.tuberculosis_H37Rv      --------------------------------------------------
Mb2049c|M.bovis_AF2122/97         LGWIIDRYRVTTDKASGIVNDPNDWCDEHANPTYIVDLIKKVTTVSVETM
Mflv_2408|M.gilvum_PYR-GCK        --------------------------------------------------
                                                                                    

Rv2024c|M.tuberculosis_H37Rv      -----------------
Mb2049c|M.bovis_AF2122/97         KIVDSIVALASAGSDST
Mflv_2408|M.gilvum_PYR-GCK        -----------------