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VVPGHEKWAERIAGGLAATKVVGTPIDNETRAMRLTQLLSRADDELLEELVGGPVVRLLESLDPTLSSPR RLRELVEALHSPEELLRDRKVRQQLLDLLPIADATEVAGLLRLDTKRPYESLRAANFKRGSKAEKILFTY LGVDTPQPPEETSALPMVESFAAYGLFSHQRDACKQSQNRLRMNPHRVLLHMPTGSGKTRTAMHIIASEL RQQEPTLVIWLAYSEELCEQAASEFEKAWHYLGDRELKTYRMWGSRDLDINDVRDGFMVAGLAKTFELMK RDPDFLARMADRVSLVIIDEAHQAIAQTYRLVLEVLCDRNEETKLLGLTATPGRTWNDPDADRELANFFN RQKVTLSVRGYDSPVDYLIDEKYLARPVFQPLFYDSNQRELSASEIQRLANTLDIPDDILERLAVDDQRN LAIISAIEGLVQKHSRVIVFAATVGHARMLAAVLRARGILANSITSGTASAERSRIIAEFRDRSDEPYVL CNYGVLTTGFDAPRTSAAVIARPTKSLVLYSQMVGRATRGTRAGGNEVATIVTVVDQNLPGFGAMEDAFM NWEDVW
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. smegmatis MC2 155 | MSMEG_1238 | - | - | 100% (566) | type III restriction enzyme, res subunit |
| M. smegmatis MC2 155 | MSMEG_5935 | - | 5e-06 | 25.09% (279) | ATP-dependent DNA helicase |
| M. smegmatis MC2 155 | MSMEG_5397 | recQ | 3e-05 | 27.82% (133) | ATP-dependent DNA helicase RecQ |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | - | - | - | - | - |
| M. gilvum PYR-GCK | Mflv_0803 | - | 4e-13 | 24.49% (392) | type III restriction enzyme, res subunit |
| M. tuberculosis H37Rv | - | - | - | - | - |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | - | - | - | - | - |
| M. marinum M | - | - | - | - | - |
| M. avium 104 | - | - | - | - | - |
| M. thermoresistible (build 8) | TH_4094 | - | 8e-13 | 26.15% (371) | PUTATIVE - |
| M. ulcerans Agy99 | - | - | - | - | - |
| M. vanbaalenii PYR-1 | - | - | - | - | - |
CLUSTAL 2.0.9 multiple sequence alignment
MSMEG_1238|M.smegmatis_MC2_155 --------------------------------------------------
Mflv_0803|M.gilvum_PYR-GCK MSNFAFLQAIGWPEMHADCRRAESYATSDPRSACFYSRRTVELLVDYLYG
TH_4094|M.thermoresistible__bu -------VDAGLYESVITQRLQRQLETLRERSAQLTPQLTEVDEAEEALT
MSMEG_1238|M.smegmatis_MC2_155 -------------MVPGHEKWAERIAGGLAATKVVGTPIDNETRAMRLTQ
Mflv_0803|M.gilvum_PYR-GCK VLALPIPYKNDLAAKINDPKFKSKVGVGIATKLNLIRKLG-NTAVHDTQQ
TH_4094|M.thermoresistible__bu LARHLMPVIERSLRCARGAEDRARLIEKLLAALGDPDALAEAVHQLDPGK
: :: : : : . :
MSMEG_1238|M.smegmatis_MC2_155 LLSRADDELLEELVG------------GPVVRLLESLDPTLSSPRR----
Mflv_0803|M.gilvum_PYR-GCK IPQRAALDALRELHHVMLWAAFRYSTKPQAVPMKVLFDPKIAAKAAPLSR
TH_4094|M.thermoresistible__bu IHRLDAVTPVALGTTHIPRPTTPLS--DAALMTNARDEPTLAAELR----
: : .: :*.:::
MSMEG_1238|M.smegmatis_MC2_155 -------------------------------------LRELVEALHSPEE
Mflv_0803|M.gilvum_PYR-GCK QEVAELAAKFAAQDEAHVKTLADKDELAAQKDTEIAALREAVKQAQAANQ
TH_4094|M.thermoresistible__bu ---------------------AELASADHVDLLCAFVKWHGLRLLERELT
. :. .
MSMEG_1238|M.smegmatis_MC2_155 LLRDR-----KVRQQLLDLLPIADATEVAG--------------------
Mflv_0803|M.gilvum_PYR-GCK QTDDRDYNEADTRDRFVDVMLAEAGWGLTETKDREYPVTGMPNGDGKGFV
TH_4094|M.thermoresistible__bu ELKERGIPLRVITTTYMGATDARALDALVNEFGAEVRVNYETDRTRLHAK
:* :. :.
MSMEG_1238|M.smegmatis_MC2_155 -----------LLRLDTKRPYES---------LRAANFKRGSKAEKILFT
Mflv_0803|M.gilvum_PYR-GCK DYVLWGEDGLPLAIVEAKRTTKSPQVGQQQAKLYADCLEKMTGRRPVIFY
TH_4094|M.thermoresistible__bu AWLLRRNTGFHTAYVGSSNLSHAALVDGLEWNVRLSAVSTPHLLEKFRAT
: :.. .: : .. . .
MSMEG_1238|M.smegmatis_MC2_155 YLGVD-------TPQPPEETS-----------------ALPMVESFAAYG
Mflv_0803|M.gilvum_PYR-GCK TNGFEHWIWDDTGGYPPREIQGFYTRDQLELLIQRRGTRKPLTDMPIDSA
TH_4094|M.thermoresistible__bu FDSYWE--NREFESYRPCEDGDKLRN--ALDVASGKKPRDPLRVTLSGLE
. * * *:
MSMEG_1238|M.smegmatis_MC2_155 LFS--HQRDACKQSQNRLRMNP-HRVLLHMPTGSGKTRTAMHIIASELRQ
Mflv_0803|M.gilvum_PYR-GCK IVERHYQHRAIRAIDDAFTAKE-REALLVMATGSGKTRTVIALVKQLMEA
TH_4094|M.thermoresistible__bu VTAKPYQAELLEQLEAERVLHDRHRNLLVAATGTGKTVIAALDYRRLVRE
: :* . : : :. ** .**:*** . :.
MSMEG_1238|M.smegmatis_MC2_155 QE--PTLVIWLAYSEELCEQAASEFEKAWHYLGDRELKTYRMWGSRDLDI
Mflv_0803|M.gilvum_PYR-GCK NW--VKRVLFLADRTALVTQAANAFKAHLPDATTVNLVTEKITDGR----
TH_4094|M.thermoresistible__bu VHGRDLSLLFVAHRKEILQQARRMYQEVLTDPTFGELLVDGEQPAR----
::::* : ** :: :* . .*
MSMEG_1238|M.smegmatis_MC2_155 NDVRDGFMVAGLAKTFELMKRDPDFLARMAD-RVSLVIIDEAHQAIAQTY
Mflv_0803|M.gilvum_PYR-GCK ------VYVCTYPTMMNLINDTDSGIRKFGPGYFDLVVIDEAHRSVYQKY
TH_4094|M.thermoresistible__bu -------WRHVFASIQSLNSER---LSTIDPEHFDVVVVDEFHHAQAASY
.. .* . : : ..:*::** *:: .*
MSMEG_1238|M.smegmatis_MC2_155 RLVLEVLCDRNEETKLLGLTATPGRTWNDPDADRELANFFNRQKVTLSVR
Mflv_0803|M.gilvum_PYR-GCK RAIFDWYDSLLVCLTATPKDEVDHNTYRLFHLEDGVPTDAYSLDDAVKEG
TH_4094|M.thermoresistible__bu RRLLDHIRP----IELLGLTATPER------GDGVDVRQFFGGRVAAELR
* ::: . . : : .
MSMEG_1238|M.smegmatis_MC2_155 GYDSPVDYLIDEKYLARPVFQPLFYDSNQRELSASEIQRLANTLDIPDDI
Mflv_0803|M.gilvum_PYR-GCK FLVPAVGISVGTKFLRQGIRYADLSEEEKDDWDALDWGDDDPPDEVSSEE
TH_4094|M.thermoresistible__bu LWD------ALEQNLLCPFHYFGIYDG--TDLEALQWKRGRYDLDELDR-
: * . : : : .* : : .
MSMEG_1238|M.smegmatis_MC2_155 LERLAVDDQRNLAIISAIEGLVQKHS------RVIVFAATVGHARMLAAV
Mflv_0803|M.gilvum_PYR-GCK INRFLFNEDTVDKVLAELMSKGHRVAEGDRLGKTIIFAKNQAHAEFIARR
TH_4094|M.thermoresistible__bu --VYTGNDARTRIILKEVRDKIADVG----AMRALGFCVSVEHARYMAKR
:: :: : . . :.: *. . **. :*
MSMEG_1238|M.smegmatis_MC2_155 LRAR-----GILANSITSGTASAERSRIIAEFRDRSDEPYVLCNYGVLTT
Mflv_0803|M.gilvum_PYR-GCK FDVQYPQYAGTFARVITHSTAYAQS--LIDNFSVTDKAPHIAISVDMLDT
TH_4094|M.thermoresistible__bu FVEA-----GIPARSVVGLDDSRERREALAALQ--SREINALFTVDLFNE
: * *. :. : : : . . .::
MSMEG_1238|M.smegmatis_MC2_155 GFDAPRTSAAVIARPTKSLVLYSQMVGRATRG----TRAGGN-------E
Mflv_0803|M.gilvum_PYR-GCK GIDVPDVVNLVFFKLVRSKTKFWQMIGRGTRLRPDLLGPGKDKQNFYVFD
TH_4094|M.thermoresistible__bu GLDIPMVDTVLFLRPTESATVFLQQLGRGLRL-----APGKTVLTALDFV
*:* * . :: : ..* . : * :**. * .*
MSMEG_1238|M.smegmatis_MC2_155 VATIVTVVDQNLPG-------------FGAMEDAFMNWEDVW--------
Mflv_0803|M.gilvum_PYR-GCK FCGNLEFFSQDLPGSEGSFQKSLNQRLFEARLGLITAIDHAWPPSEPEPE
TH_4094|M.thermoresistible__bu GHHRREFRFDQRFRALTGLSRKRLEKQVQEGFPFLPSGSQIVLDEVAQKI
. :: . : ..
MSMEG_1238|M.smegmatis_MC2_155 --------------------------------------------------
Mflv_0803|M.gilvum_PYR-GCK EGQGTETERGLRVDVAWSLHRSVAGMNLDNFLVRPHRRLVEQYSQWPAWT
TH_4094|M.thermoresistible__bu VLENVRQQVSPKKSVLVSEIRSHPDDRLASYLEESGRGLDDILRPNRSWT
MSMEG_1238|M.smegmatis_MC2_155 --------------------------------------------------
Mflv_0803|M.gilvum_PYR-GCK SLTPEVAGDVAEHLAGLPSLHKDDDEDAKRFDMLVLRRQLAQLEGDAVAA
TH_4094|M.thermoresistible__bu TLCRDAG-------------KLAEQPGPREAELVKRLKALAHVDDRKRAD
MSMEG_1238|M.smegmatis_MC2_155 --------------------------------------------------
Mflv_0803|M.gilvum_PYR-GCK ERLREQIQNIATGLLSQTAIPSVKAQEALLDEVGGDEWWIDVTLPMLESV
TH_4094|M.thermoresistible__bu AYRRLLASDVRSDSLAERRLADMLFYSLYPDGGGFEAAADGFDEVRREIV
MSMEG_1238|M.smegmatis_MC2_155 --------------------------------------------------
Mflv_0803|M.gilvum_PYR-GCK RRKLRGLLRFLEKAKRNQVYTDFADELSEASLVDLPGITPGTNWERFQAK
TH_4094|M.thermoresistible__bu VAEMRQIIDIAFDAAHRRTS------ELGEVIPELRDVPLALHATYSREE
MSMEG_1238|M.smegmatis_MC2_155 --------------------------------------------------
Mflv_0803|M.gilvum_PYR-GCK ARAYLRRHQDHVALQRLRRNKPLTPDDLASLEQMLIESGTGEQADIELAK
TH_4094|M.thermoresistible__bu ILAALGWVSPGRKPSTMREGVAWCPEVNADAFLITLKKSDTEYSPTTMYR
MSMEG_1238|M.smegmatis_MC2_155 --------------------------------------------------
Mflv_0803|M.gilvum_PYR-GCK EQSHGLGLFVRSLVGLDREAAAEAFGAYLDGTKFNADQIRFVNLIITELT
TH_4094|M.thermoresistible__bu DFALSPDLFHWESQ--STTTASSPTGQRYIHHRERGSHVLLFVREAKKGA
MSMEG_1238|M.smegmatis_MC2_155 --------------------------------------------------
Mflv_0803|M.gilvum_PYR-GCK ANGFMEPVRLYESPYIDHAPTGPDDVFGDADVDTIVAILNSVRDNAAPKD
TH_4094|M.thermoresistible__bu FGDGAPYIFLGPADYVSHEGDRPMAITWRLRRPMPTEVYLGARAAVA---
MSMEG_1238|M.smegmatis_MC2_155 ---
Mflv_0803|M.gilvum_PYR-GCK GAA
TH_4094|M.thermoresistible__bu ---