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MTSSTPGPIITRDMVLLDASVDGDKQAVIARLVAALASAGRTGEAAGLVGAAMAREEQSATGLPGGIAIP HCRSPYVDTPTIGFARLKPAVDFGAPDGPADLAFLIAAPDSGGQEHMKLLSSLARALVRKDFVESLRNAA TADEVVDLVEGVVNPAPVAPAAAAPAAAPAAAPPAAKTIVAITACPTGIAHTYMAADSLSQAAKEAGVTL VVETQGSSGSTPVPSDTIAKADAVIFATDVGVKDKGRFAGKPVVASGVKRAINEPAKMIAEAVAAADNPN AARVEGSGSAAPDAPSGNVGWGTRTRQILLTGVSYMIPFVAAGGLLIALGFLFGGYEIADSGNDIALNNS LTNLPDGGFLQYLGAILFTLGGLAFSFLVPALAGYISFAIADRPGLAPGFTAGALAVFVGGGFIGGIVGG VIAGFAALWISNIKTPAWLRGLMPVVIIPLIASLAVGLIMFFLIGRPLALINTGLTNWLNSLTGTSAVLL GVILGLMMCFDLGGPVNKAAYAFATAGLAAATTGSFQIMAAVMAAGMVPPLAMALATTIRPGLFSEPERE NGRAAWLLGASFISEGAIPFAAADPLRVIPSMMFGGAITGALCMAFGVTLRAPHGGIFVFFAIGNLLWFV IALVVGTVVAGLTVVAAKQFIKPADRTDADLVAA
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. gilvum PYR-GCK | Mflv_0752 | - | - | 100% (664) | PTS system, fructose subfamily, IIC subunit |
| M. gilvum PYR-GCK | Mflv_3843 | - | 9e-06 | 25.81% (403) | hypothetical protein Mflv_3843 |
| M. gilvum PYR-GCK | Mflv_1219 | - | 3e-05 | 26.28% (156) | PTS system, mannitol-specific IIC subunit |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0030 | - | 0.0001 | 27.64% (199) | hypothetical protein Mb0030 |
| M. tuberculosis H37Rv | Rv0029 | - | 0.0001 | 27.64% (199) | hypothetical protein Rv0029 |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | - | - | - | - | - |
| M. marinum M | MMAR_4294 | - | 4e-05 | 25.19% (262) | hypothetical protein MMAR_4294 |
| M. avium 104 | MAV_2390 | - | 7e-05 | 29.41% (153) | hypothetical protein MAV_2390 |
| M. smegmatis MC2 155 | MSMEG_0085 | - | 0.0 | 75.23% (666) | PTS system, Fru family protein, IIABC components |
| M. thermoresistible (build 8) | TH_2930 | - | 0.0001 | 30.36% (168) | PUTATIVE protein of unknown function DUF140 |
| M. ulcerans Agy99 | MUL_1004 | - | 3e-05 | 26.39% (216) | hypothetical protein MUL_1004 |
| M. vanbaalenii PYR-1 | Mvan_0094 | - | 0.0 | 87.05% (664) | PTS system, fructose subfamily, IIC subunit |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_0752|M.gilvum_PYR-GCK MTSSTPGPIITRDMVLLDASVDGDKQAVIARLVAALASAGRTGEAAGLVG
Mvan_0094|M.vanbaalenii_PYR-1 MTSST-APIITRDLVLLDVAIDGDKQAVIARLVNALAAAGRTDDADGLIG
MSMEG_0085|M.smegmatis_MC2_155 ----MTQPIITDDLVLLDVDAGSDKEAVIARLAGALGGAGRASDTAGLVG
Mb0030|M.bovis_AF2122/97 ---------------------------------------------MAIFG
Rv0029|M.tuberculosis_H37Rv ---------------------------------------------MAIFG
MMAR_4294|M.marinum_M -----------------------------------------------MAS
MUL_1004|M.ulcerans_Agy99 -----------------------------------------------MAS
MAV_2390|M.avium_104 --------------------------------------------------
TH_2930|M.thermoresistible__bu --------------------------------------------------
Mflv_0752|M.gilvum_PYR-GCK AAMAREEQSATGLPGGIAIPHCRSPYVDTPTIGFARLKPAVDFGAPDGPA
Mvan_0094|M.vanbaalenii_PYR-1 AAMAREEQSATGLPGGIAIPHCRSPYVDTPTIGFARLTPGVDFGAPDGPA
MSMEG_0085|M.smegmatis_MC2_155 AAMAREAQSATGLPGGIAIPHCRSPYVDTATIGFARLDPKVDFGAPDGPA
Mb0030|M.bovis_AF2122/97 RWSARQRLRRATRESLTIPTFSSSLDCT------------TRVIGGLWPA
Rv0029|M.tuberculosis_H37Rv RWSARQRLRRATRESLTIPTFSSSLDCT------------TRVIGGLWPA
MMAR_4294|M.marinum_M TWSLSKGLAAVVVTSAAAFGLCPGAAADPAAP---QPNPNPQLPGLPALA
MUL_1004|M.ulcerans_Agy99 TWSLSKGLAAVVVTSAAAFGLCPAAAADPAAP---QPNPNPQLPGLPALA
MAV_2390|M.avium_104 -MTATLTTPLDGVDGVAAIRNWSVGYVK-----------------RHPVA
TH_2930|M.thermoresistible__bu -MTRS--------DGVEVIGEWAGGYIR-----------------RHPLA
. *
Mflv_0752|M.gilvum_PYR-GCK DLAFLIAAPDSGGQEHMKLLSSLARALVRKDFVESLRNAATADEVVDLVE
Mvan_0094|M.vanbaalenii_PYR-1 DLAFLIAAPDSGGQEHMKLLSSLARALVRKDFVESLRNAGSADEVVALVE
MSMEG_0085|M.smegmatis_MC2_155 DLAFLIAAPESGGSEHMKLLSSLARALVRKDFVESLRSASSTQEVVELVN
Mb0030|M.bovis_AF2122/97 ELSSNTAETATLAEHLKADLHRIVGSAN-DELMVIWRAGMADSTRRAEED
Rv0029|M.tuberculosis_H37Rv ELSSNTAETATLAEHLKADLHRIVGSAN-DELMVIWRAGMADSTRRAEED
MMAR_4294|M.marinum_M QLSPIIQQAAGNPEQATQLLMAAAQAFA-HNPAAPTESRNVASSVNQFVQ
MUL_1004|M.ulcerans_Agy99 QLSPIIQQAAGNPEQATQLLMAAAQAFA-HNPAAPTESRNVASSVNQFVQ
MAV_2390|M.avium_104 SLTTVGEQFVLGVRTIQYFFYDLITGRFQWQEFVRQGAFMAGTAVLP---
TH_2930|M.thermoresistible__bu ALGTVGEQFVLGVRTLQYLFVDLFTGRFQWWEFVRQAAFMAGTAVLP---
* : .
Mflv_0752|M.gilvum_PYR-GCK GVVNPAPVAPAAAAPAAA-PAAAPPAAKTIVAITACPTGIAHTYMAADSL
Mvan_0094|M.vanbaalenii_PYR-1 GVVNPAPAAPPAP--------VEKPAAKTIVAITACPTGIAHTYMAADAL
MSMEG_0085|M.smegmatis_MC2_155 SAVKPAAAPPASAPKPAAEPKPAADKSVSIVAVTSCPTGIAHTYMAADAL
Mb0030|M.bovis_AF2122/97 RVIDRARASAMRR--------VESAMRELRQITGRVPVEIPRMRGAG---
Rv0029|M.tuberculosis_H37Rv RVIDRARASAMRR--------VESAMRELRQITGRVPVEIPRMRGAG---
MMAR_4294|M.marinum_M EPVNPAPGSPPLG--------VPAPAAAPVEVAPPASAPVPHVPAPG---
MUL_1004|M.ulcerans_Agy99 EPVNPAPGSPPLG--------VPAPAAAPVEVAPPASAPVPHVPAPG---
MAV_2390|M.avium_104 --------------------------TILVSLPISVTLSIQFALLAG---
TH_2930|M.thermoresistible__bu --------------------------TVLVALPIGVTLSIQFALLAG---
. : ..
Mflv_0752|M.gilvum_PYR-GCK SQAAKEAGVTLVVETQGSSGSTPVPSDTIAKADAVIFATDVGVKDKGRFA
Mvan_0094|M.vanbaalenii_PYR-1 AAAAKEAGVTLVVETQGSSGSTPLPSDTIAGADAVIFATDVGVKDRGRFA
MSMEG_0085|M.smegmatis_MC2_155 KAAAEKAGVACTVETQGSAGSTPLSAETIAAADAVIFATDVGVKDRQRFA
Mb0030|M.bovis_AF2122/97 -------------GSDLDTTRLMPAVTVVQPADQACTDWPVAAAEDDE-A
Rv0029|M.tuberculosis_H37Rv -------------GSDLDTTRLMPAVTVVQPADQACTDWPVAAAEDDE-A
MMAR_4294|M.marinum_M -------------AEPGTLAHLPAGIDPAHAAGPAPVAAPAGAPPASAPA
MUL_1004|M.ulcerans_Agy99 -------------AEPGTLAHLPAGIDPAHAAGPAPVAAPAGAPPASAPA
MAV_2390|M.avium_104 --------------QVGATSLAGAASGLAVIRQGASLVAAVLMASAVGSA
TH_2930|M.thermoresistible__bu --------------QVGATSLAGAASGLAVIRQAASLTAAILMAAAVGSA
. *
Mflv_0752|M.gilvum_PYR-GCK GKPVVASGVKRAINEPAKMIAEAVAAADNPNAARVEGSGSAAPDAPSGNV
Mvan_0094|M.vanbaalenii_PYR-1 GKPVVASGVKRAINEPAKMIAEAVAAADNPNAPRVEGSGAAASEAPSGDV
MSMEG_0085|M.smegmatis_MC2_155 GKPVIASGVKRAINEPDKMVAEAISAASDPGAPWVAGQAAESASAPAGDV
Mb0030|M.bovis_AF2122/97 RLQRLLAFVARQEPRLNWAVGVNADGTTVLVTDVAHGWIPPGIALPEG--
Rv0029|M.tuberculosis_H37Rv RLQRLLAFVARQEPRLNWAVGVHADGTTVLVTDVAHGWIPPGIALPEG--
MMAR_4294|M.marinum_M PAAAAPASAPGTAPAPAAAPGPAPAAPAPAPAAAAPAPAPAPAAPPAAPV
MUL_1004|M.ulcerans_Agy99 PAAAAPASAPGTAPAPAAAPGPAPAAPAPAPAAAAPAPAPAPAAPPAAPV
MAV_2390|M.avium_104 ITADLGSRTMREETDAMEVMGVSVVRRLVVPRFAAAVMIGVALTG-----
TH_2930|M.thermoresistible__bu ITADLGSRTMREETDAMEVMGVSVIRRLVVPRFAAAIMIGVALTG-----
: . . .
Mflv_0752|M.gilvum_PYR-GCK GWGTRTRQILLTGVSYMIPFVAAGGLLIALGFLFGGYEIADS--------
Mvan_0094|M.vanbaalenii_PYR-1 GWGTRTRQILLTGVSYMIPFVAAGGLLIALGFLFAGYEIADT--------
MSMEG_0085|M.smegmatis_MC2_155 GWGTRIRQILLTGVSYMIPFVAAGGLLIALGFLLAGYEIGNTPDGETQSL
Mb0030|M.bovis_AF2122/97 -------------VRLLAPARRAGRAPELVG-------------------
Rv0029|M.tuberculosis_H37Rv -------------VRLLAPARRAGRAPELVG-------------------
MMAR_4294|M.marinum_M AA----------PAPVPAPAPAAAPAPEAAAPAPA---------------
MUL_1004|M.ulcerans_Agy99 AAPV------AAPAPVPAPAPAAAPAPEAAAPAPA---------------
MAV_2390|M.avium_104 --------------------------------------------------
TH_2930|M.thermoresistible__bu --------------------------------------------------
Mflv_0752|M.gilvum_PYR-GCK GNDIALNNSLTNLPDGGFLQYLGAILFTLGGLAFSFLVPALAGYISFAIA
Mvan_0094|M.vanbaalenii_PYR-1 GNDIALNNSLTNLPPGGFLEYLGAILFSLGGLAFGFLVPALAGYISFAIA
MSMEG_0085|M.smegmatis_MC2_155 GNIIATHNSLTNLPSGGVAQYLGAVLFTLGGLAFSFLVPALAGYIAFAIA
Mb0030|M.bovis_AF2122/97 ---------------------------------------ITTCCKTYTPG
Rv0029|M.tuberculosis_H37Rv ---------------------------------------ITTCCKTYTPG
MMAR_4294|M.marinum_M ------------------------------------PAPAPAAAPGFGPD
MUL_1004|M.ulcerans_Agy99 ------------------------------------PAPAPAAAPGFGPD
MAV_2390|M.avium_104 ----------------------------------------VVCFAGFFAS
TH_2930|M.thermoresistible__bu ----------------------------------------VVCFVGFLAS
. :
Mflv_0752|M.gilvum_PYR-GCK DRPGLAPGFTAGALAVFVGGGFIGGIVGGVIAGFAALWISNIKTPAWLRG
Mvan_0094|M.vanbaalenii_PYR-1 DRPGIAPGFTAGALAVFIGGGFIGGIVGGVLAGFAALWISNLKVPQWFRG
MSMEG_0085|M.smegmatis_MC2_155 DRPGIAPGFTAGAVAVFVGGGFIGGIVGGLIAGFAALWISRIGVPQWARG
Mb0030|M.bovis_AF2122/97 DSLRRAVDSTAPTSSVQPRA------LPAIAGLSVELGIATQRHDG----
Rv0029|M.tuberculosis_H37Rv DSLRRAVDSTAPTSSVQPRA------LPAIAGLSVELGIATQRHDG----
MMAR_4294|M.marinum_M APPTQDFMYPSIGTNCLADG------SNIIATALSVAGPATIPTPGPGPG
MUL_1004|M.ulcerans_Agy99 APPTQDFMYPSIGTNCLADG------SNIIATALSVAGPATIPTPGPGPG
MAV_2390|M.avium_104 YMFNVYFQNGAPGSFVSTSA------------------------------
TH_2930|M.thermoresistible__bu YLFNVYFQNGAPGSFVATFA------------------------------
: .
Mflv_0752|M.gilvum_PYR-GCK LMPVVIIPLIASLAVGLIMFFLIGRPLALINTGLTNWLNSLTGTSAVLLG
Mvan_0094|M.vanbaalenii_PYR-1 LMPVVIVPLGASLFVGLIMFFLVGRPLALINSGLTNWLSGLSGTSAIFLG
MSMEG_0085|M.smegmatis_MC2_155 LMPVVVIPLFASMVVGLLMFLLLGRPLAALTSGLTNWLGGLSGGSAIALG
Mb0030|M.bovis_AF2122/97 -LPKIVH-------------------------------------------
Rv0029|M.tuberculosis_H37Rv -LPKIVH-------------------------------------------
MMAR_4294|M.marinum_M QTAYVFT-------------------------------------------
MUL_1004|M.ulcerans_Agy99 QTAYVFT-------------------------------------------
MAV_2390|M.avium_104 --------------------------------------------------
TH_2930|M.thermoresistible__bu --------------------------------------------------
Mflv_0752|M.gilvum_PYR-GCK VILGLMMCFDLGGPVNKAAYAFATAGLAAATTGSFQIMAAVMAAGMVPPL
Mvan_0094|M.vanbaalenii_PYR-1 IILGLMMCFDLGGPVNKAAYAFATAGLAAETTASFEIMAAVMAAGMVPPL
MSMEG_0085|M.smegmatis_MC2_155 VILGLMMCFDLGGPVNKAAYAFATASLVNPTQANLQIMAAVMAAGMVPPL
Mb0030|M.bovis_AF2122/97 --------------------AMATAAGNGAAAEEVDLLRVHVDTALHHVL
Rv0029|M.tuberculosis_H37Rv --------------------AMATAAGNGAAAEEVDLLRVHVDTALHHVL
MMAR_4294|M.marinum_M --------------------AVGTPGPAEVQRLPLNVTWVNLTTGKSGSV
MUL_1004|M.ulcerans_Agy99 --------------------AVGTPGPAEVQRLPLNVTWVNLTTGKSGSV
MAV_2390|M.avium_104 --------------------SFATTG-----DMILALLKAIVFGAIVAIV
TH_2930|M.thermoresistible__bu --------------------SFTTTG-----DMLVALIKAVVFGAIVAVV
:. *.. . : . : . :
Mflv_0752|M.gilvum_PYR-GCK AMALATTIRPGLFSEPERENGRAAWLLGASFISEGAIPFAAADPLRVIPS
Mvan_0094|M.vanbaalenii_PYR-1 AMALATTIRPGLFSEPERENGRAAWLLGASFISEGAIPFAAADPLRVIPS
MSMEG_0085|M.smegmatis_MC2_155 AMALATVIRPRLFSEPERENGRAAWLLGASFITEGAIPFAAADPLRVIPS
Mb0030|M.bovis_AF2122/97 AQYPR--VDPALLLNCMLLAATER-----SVTGDPIAANYHFAWFRELDS
Rv0029|M.tuberculosis_H37Rv AQYPR--VDPALLLNCMLLAATER-----SVTGDPIAANYHFAWFRELDS
MMAR_4294|M.marinum_M TLKPRSDINPEGPTTLTGIADTGSGSIMSTIFGQVTTKERQCQFMPTIGS
MUL_1004|M.ulcerans_Agy99 TLKPRSDINPEGPTTLTGIADTGSGSIMSTIFGQVTTKERQCQFMPTIGS
MAV_2390|M.avium_104 SSQKGLSTKGGPTGVANSVNAAVVEAILLLMIVNVAISQLYIMLSPRTGL
TH_2930|M.thermoresistible__bu SCQKGLSTKGGPTGVANSVNAAVVESILVLMIVNVGISQLYIMLFPRVGL
: . :
Mflv_0752|M.gilvum_PYR-GCK MMFGGAITGALCMAFGVTLRAPHGGIFVFFAIGNLLWFVIALVVGTVVAG
Mvan_0094|M.vanbaalenii_PYR-1 MMFGGAITGALCMAFGATSRAPHGGIFVLFAIDNKLGFVIALVAGTVAAA
MSMEG_0085|M.smegmatis_MC2_155 MMVGGAVTGATVMAAAVTLRAPHGGIFVFFAIGNLLWFVIAVALGTVVSA
Mb0030|M.bovis_AF2122/97 RR------------------------------------------------
Rv0029|M.tuberculosis_H37Rv RR------------------------------------------------
MMAR_4294|M.marinum_M TVVP----------------------------------------------
MUL_1004|M.ulcerans_Agy99 TVVP----------------------------------------------
MAV_2390|M.avium_104 --------------------------------------------------
TH_2930|M.thermoresistible__bu --------------------------------------------------
Mflv_0752|M.gilvum_PYR-GCK LTVVAAKQFIK--PADRTDADLVAA
Mvan_0094|M.vanbaalenii_PYR-1 LAVVAAKQFIK--AGAKTEPELVTA
MSMEG_0085|M.smegmatis_MC2_155 LTVIAAKQFTKRPVTAPEAPALATT
Mb0030|M.bovis_AF2122/97 -------------------------
Rv0029|M.tuberculosis_H37Rv -------------------------
MMAR_4294|M.marinum_M -------------------------
MUL_1004|M.ulcerans_Agy99 -------------------------
MAV_2390|M.avium_104 -------------------------
TH_2930|M.thermoresistible__bu -------------------------