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VAIFGRWSARQRLRRATRESLTIPTFSSSLDCTTRVIGGLWPAELSSNTAETATLAEHLKADLHRIVGSA NDELMVIWRAGMADSTRRAEEDRVIDRARASAMRRVESAMRELRQITGRVPVEIPRMRGAGGSDLDTTRL MPAVTVVQPADQACTDWPVAAAEDDEARLQRLLAFVARQEPRLNWAVGVHADGTTVLVTDVAHGWIPPGI ALPEGVRLLAPARRAGRAPELVGITTCCKTYTPGDSLRRAVDSTAPTSSVQPRALPAIAGLSVELGIATQ RHDGLPKIVHAMATAAGNGAAAEEVDLLRVHVDTALHHVLAQYPRVDPALLLNCMLLAATERSVTGDPIA ANYHFAWFRELDSRR
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. tuberculosis H37Rv | Rv0029 | - | - | 100% (365) | hypothetical protein Rv0029 |
| M. tuberculosis H37Rv | Rv2082 | - | 4e-32 | 39.45% (256) | hypothetical protein Rv2082 |
| M. tuberculosis H37Rv | Rv3899c | - | 5e-27 | 33.88% (245) | hypothetical protein Rv3899c |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0030 | - | 0.0 | 99.73% (365) | hypothetical protein Mb0030 |
| M. gilvum PYR-GCK | Mflv_0752 | - | 6e-05 | 27.64% (199) | PTS system, fructose subfamily, IIC subunit |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | - | - | - | - | - |
| M. marinum M | MMAR_0048 | - | 2e-99 | 55.01% (369) | hypothetical protein MMAR_0048 |
| M. avium 104 | MAV_0048 | - | 3e-62 | 52.26% (243) | hypothetical protein MAV_0048 |
| M. smegmatis MC2 155 | - | - | - | - | - |
| M. thermoresistible (build 8) | - | - | - | - | - |
| M. ulcerans Agy99 | MUL_0047 | - | 2e-98 | 54.22% (367) | hypothetical protein MUL_0047 |
| M. vanbaalenii PYR-1 | - | - | - | - | - |
CLUSTAL 2.0.9 multiple sequence alignment
Rv0029|M.tuberculosis_H37Rv -------------------------MAIFGRWSARQRLRRATRESLTIP-
Mb0030|M.bovis_AF2122/97 -------------------------MAIFGRWSARQRLRRATRESLTIP-
MMAR_0048|M.marinum_M -------------------------MAIFGRRTARQRLRKAAQESLAIP-
MUL_0047|M.ulcerans_Agy99 -------------------------MAIFGRRTARQRLRKAAQESLVIP-
MAV_0048|M.avium_104 -------------------------MAIFGRMTARQRLRRATRESLSIP-
Mflv_0752|M.gilvum_PYR-GCK MTSSTPGPIITRDMVLLDASVDGDKQAVIARLVAALASAGRTGEAAGLVG
*::.* * : *: :
Rv0029|M.tuberculosis_H37Rv -TFSSSLDCTTRVIGGLWPAELSSNTAETATL------------AEHLKA
Mb0030|M.bovis_AF2122/97 -TFSSSLDCTTRVIGGLWPAELSSNTAETATL------------AEHLKA
MMAR_0048|M.marinum_M -AFSSPPDCTPWVIGGLWPTELSRDAPETATL------------AEYLEA
MUL_0047|M.ulcerans_Agy99 -AFSSPPDCTPWVIGGLWPTELSRDAPETATL------------AEYLEA
MAV_0048|M.avium_104 -AFSSPVDCTPWVTGGLWPAELSTVTPETATL------------AEYLKA
Mflv_0752|M.gilvum_PYR-GCK AAMAREEQSATGLPGGIAIPHCRSPYVDTPTIGFARLKPAVDFGAPDGPA
::: :.:. : **: .. :*.*: * *
Rv0029|M.tuberculosis_H37Rv DLHRIVGSAN----DELMVIWRAGMADSTRRAEEDRVIDRARASAMRRVE
Mb0030|M.bovis_AF2122/97 DLHRIVGSAN----DELMVIWRAGMADSTRRAEEDRVIDRARASAMRRVE
MMAR_0048|M.marinum_M DLQRIADSAN----EELASLRHAVMLDSDRRAAEARVIDDARARAVQRVE
MUL_0047|M.ulcerans_Agy99 DLQRIADSAN----EELASLRHAVMLDSDRRAAEARVIDEARARAVQRIE
MAV_0048|M.avium_104 DLQRIADGAN----DELRKLKRAGMTDTARQAAEARVIEQARTRAVRRVE
Mflv_0752|M.gilvum_PYR-GCK DLAFLIAAPDSGGQEHMKLLSSLARALVRKDFVESLRNAATADEVVDLVE
** : ..: :.: : : * : .: :*
Rv0029|M.tuberculosis_H37Rv SAMRELRQITGRVPVEIPR-------------------------------
Mb0030|M.bovis_AF2122/97 SAMRELRQITGRVPVEIPR-------------------------------
MMAR_0048|M.marinum_M SARNQLREGASTEPPVAPP-------------------------------
MUL_0047|M.ulcerans_Agy99 SARNQLREGASTEPPVAPR-------------------------------
MAV_0048|M.avium_104 STIRYLHAVQSGARPPAPPRPTLDAPGADLERTQVLPAVGDAEHTAGPPA
Mflv_0752|M.gilvum_PYR-GCK GVVNPAPVAPAAAAPAAAPAAAPPAAKTIVAITACPTGIAHTYMAADSLS
.. . . .
Rv0029|M.tuberculosis_H37Rv -----------------------------------MRGAGGSDLDT----
Mb0030|M.bovis_AF2122/97 -----------------------------------MRGAGGSDLDT----
MMAR_0048|M.marinum_M ----------------------------------DVADPNAAEPGS----
MUL_0047|M.ulcerans_Agy99 ----------------------------------DIADPNAGEPGS----
MAV_0048|M.avium_104 QQTPEARPRPTRRRAAEDEPAQLEETRVLPAIRDDAAAADASVPETPASE
Mflv_0752|M.gilvum_PYR-GCK QAAKEAG-------------------------VTLVVETQGSSGSTPVPS
. .. :
Rv0029|M.tuberculosis_H37Rv -------------------TRLMPAVTVVQPADQACTDWPVAA-------
Mb0030|M.bovis_AF2122/97 -------------------TRLMPAVTVVQPADQACTDWPVAA-------
MMAR_0048|M.marinum_M -----------------QPQPPTAGRPDAVDAARAAARAPAPA-------
MUL_0047|M.ulcerans_Agy99 -----------------QPQPPMAGRPDAVDAARAAARAPAPA-------
MAV_0048|M.avium_104 TPVPEAPAAEAPVPEAPAPEAPAAEVPEAPAPEAPAAEVPEPLGEPTTRG
Mflv_0752|M.gilvum_PYR-GCK DTIAKADAVIFATDVGVKDKGRFAGKPVVASGVKRAINEPAKMIAEAVAA
. . . . *
Rv0029|M.tuberculosis_H37Rv ------------------------------------AED-----------
Mb0030|M.bovis_AF2122/97 ------------------------------------AED-----------
MMAR_0048|M.marinum_M -----------------------------------------VPES-----
MUL_0047|M.ulcerans_Agy99 -----------------------------------------VPES-----
MAV_0048|M.avium_104 RHHAPVPEPVAERVEPDIAAPAEAADLEQTQVIPVVRRDEPVPEPPVVAP
Mflv_0752|M.gilvum_PYR-GCK ADNPNAARVEGSGSAAPDAPSGNVGWGTRTRQILLTGVSYMIPFVAAGGL
Rv0029|M.tuberculosis_H37Rv -------------------------------------------------D
Mb0030|M.bovis_AF2122/97 -------------------------------------------------D
MMAR_0048|M.marinum_M -------------------------------------------------D
MUL_0047|M.ulcerans_Agy99 -------------------------------------------------D
MAV_0048|M.avium_104 PEPAEEPADSGRHHAPADRDEPATEGRTAVADTDTAQPRVEKPAPTTVFD
Mflv_0752|M.gilvum_PYR-GCK LIALGFLFGGYEIADSGNDIALNNSLTNLPDGGFLQYLGAILFTLGGLAF
Rv0029|M.tuberculosis_H37Rv EARLQRLLAFVARQEP-RLNWAVGVHADGTTVLVTDVAHGWIPPGIALPE
Mb0030|M.bovis_AF2122/97 EARLQRLLAFVARQEP-RLNWAVGVNADGTTVLVTDVAHGWIPPGIALPE
MMAR_0048|M.marinum_M DQRLRRLLMFVARQEP-RLNWAIGQRPEG-TVLVTDVAHGWIPPGIALPQ
MUL_0047|M.ulcerans_Agy99 DQRLRRLLMFVARQEP-RLNWAIGRQSEG-TVLVTDVAHGWIPPGIALPQ
MAV_0048|M.avium_104 NNRLNRLLEFVVRQEP-RLNWAIGDRADGTTILVTDLAHGWIPSGIALPA
Mflv_0752|M.gilvum_PYR-GCK SFLVPALAGYISFAIADRPGLAPGFTAGALAVFVGGGFIGGIVGGVIAGF
. : * :: . * . * * . . :::* . * * *:
Rv0029|M.tuberculosis_H37Rv GVRLLAPARRAGRAPELVGITTC----------CKTYTPGDSLRRAVDST
Mb0030|M.bovis_AF2122/97 GVRLLAPARRAGRAPELVGITTC----------CKTYTPGDSLRRAVDST
MMAR_0048|M.marinum_M GVRLLPPKRRSGRLAALVDAATG----------LLSYSPGDPLPWADEDT
MUL_0047|M.ulcerans_Agy99 GVRLLPPKRRSGRLAALVDAATG----------SLSYSPGDPLPWVDEDT
MAV_0048|M.avium_104 GVRLLEPERRSGDVVALIGETVR----------RVTYTPGDTLRRSADFA
Mflv_0752|M.gilvum_PYR-GCK AALWISNIKTPAWLRGLMPVVIIPLIASLAVGLIMFFLIGRPLALINTGL
.. : : .. *: . : * .*
Rv0029|M.tuberculosis_H37Rv APTSSVQPRALPAIAGLSVELGIATQRHDGLPKIVHAMATAAGNG--AAA
Mb0030|M.bovis_AF2122/97 APTSSVQPRALPAIAGLSVELGIATQRHDGLPKIVHAMATAAGNG--AAA
MMAR_0048|M.marinum_M ATRSSVRPRELPMADNVARELCDATRSRVGLPRRAHVLAKAADAGTAVVE
MUL_0047|M.ulcerans_Agy99 ATRSSVRPRELPMADNVARELCDATRSRVGLPRMAHVLAKAADAGTAVVE
MAV_0048|M.avium_104 ATQSSSQPRELPPIDDLATAISRAIRGRAGLPKIVPRLADAAAAGAVIVD
Mflv_0752|M.gilvum_PYR-GCK TNWLNSLTGTSAVLLGVILGLMMCFDLGGPVNKAAYAFATAGLAAATTGS
: . . . .: : . : : . :* *. .
Rv0029|M.tuberculosis_H37Rv EEVDLLRVHVDTALHHVLAQYPRVDPALLLN-------------------
Mb0030|M.bovis_AF2122/97 EEVDLLRVHVDTALHHVLAQYPRVDPALLLN-------------------
MMAR_0048|M.marinum_M DEIDLLRVHLDTARHEVVAHYPSIDGEVLLN-------------------
MUL_0047|M.ulcerans_Agy99 DEIDLLRVHLDTARHQIVAHYPSIDGEVLLN-------------------
MAV_0048|M.avium_104 QEVDVLRVHLDTARYQLLVQYPNVNPALLLK-------------------
Mflv_0752|M.gilvum_PYR-GCK FQIMAAVMAAGMVPPLAMALATTIRPGLFSEPERENGRAAWLLGASFISE
:: : . . :. . : :: :
Rv0029|M.tuberculosis_H37Rv -------CMLLAATERSVTGDPIAANYHFAWFRELDSRR-----------
Mb0030|M.bovis_AF2122/97 -------CMLLAATERSVTGDPIAANYHFAWFRELDSRR-----------
MMAR_0048|M.marinum_M -------CMLLAATASSVSGDAVTANYHLAWFRELNA-------------
MUL_0047|M.ulcerans_Agy99 -------WMLLAATASSVNGDAVTANYHLAWFRELKA-------------
MAV_0048|M.avium_104 -------CLLMATTEGIASGDPVSANYHLAWYRTLAAPSPGG--------
Mflv_0752|M.gilvum_PYR-GCK GAIPFAAADPLRVIPSMMFGGAITGALCMAFGVTLRAPHGGIFVFFAIGN
: . *..::. :*: * :
Rv0029|M.tuberculosis_H37Rv ---------------------------------------
Mb0030|M.bovis_AF2122/97 ---------------------------------------
MMAR_0048|M.marinum_M ---------------------------------------
MUL_0047|M.ulcerans_Agy99 ---------------------------------------
MAV_0048|M.avium_104 ---------------------------------------
Mflv_0752|M.gilvum_PYR-GCK LLWFVIALVVGTVVAGLTVVAAKQFIKPADRTDADLVAA