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VAIFGRWSARQRLRRATRESLTIPTFSSSLDCTTRVIGGLWPAELSSNTAETATLAEHLKADLHRIVGSA NDELMVIWRAGMADSTRRAEEDRVIDRARASAMRRVESAMRELRQITGRVPVEIPRMRGAGGSDLDTTRL MPAVTVVQPADQACTDWPVAAAEDDEARLQRLLAFVARQEPRLNWAVGVNADGTTVLVTDVAHGWIPPGI ALPEGVRLLAPARRAGRAPELVGITTCCKTYTPGDSLRRAVDSTAPTSSVQPRALPAIAGLSVELGIATQ RHDGLPKIVHAMATAAGNGAAAEEVDLLRVHVDTALHHVLAQYPRVDPALLLNCMLLAATERSVTGDPIA ANYHFAWFRELDSRR
Operon Prediction Model: Genebank
Paralogs
species | id | gene | e-value | identity (len) | annotation |
M. bovis AF2122 / 97 | Mb0030 | - | - | 100% (365) | hypothetical protein Mb0030 |
M. bovis AF2122 / 97 | Mb2108 | - | 2e-32 | 39.45% (256) | hypothetical protein Mb2108 |
M. bovis AF2122 / 97 | Mb3928c | - | 5e-27 | 33.88% (245) | hypothetical protein Mb3928c |
Closest Orthologs (e-value cutoff: 1e-4)
species | id | gene | e-value | identity (len) | annotation |
M. gilvum PYR-GCK | Mflv_0752 | - | 6e-05 | 27.64% (199) | PTS system, fructose subfamily, IIC subunit |
M. tuberculosis H37Rv | Rv0029 | - | 0.0 | 99.73% (365) | hypothetical protein Rv0029 |
M. leprae Br4923 | - | - | - | - | - |
M. abscessus ATCC 19977 | - | - | - | - | - |
M. marinum M | MMAR_0048 | - | 2e-99 | 55.01% (369) | hypothetical protein MMAR_0048 |
M. avium 104 | MAV_0048 | - | 3e-62 | 52.26% (243) | hypothetical protein MAV_0048 |
M. smegmatis MC2 155 | - | - | - | - | - |
M. thermoresistible (build 8) | - | - | - | - | - |
M. ulcerans Agy99 | MUL_0047 | - | 2e-98 | 54.22% (367) | hypothetical protein MUL_0047 |
M. vanbaalenii PYR-1 | - | - | - | - | - |
CLUSTAL 2.0.9 multiple sequence alignment Mb0030|M.bovis_AF2122/97 -------------------------MAIFGRWSARQRLRRATRESLTIP- Rv0029|M.tuberculosis_H37Rv -------------------------MAIFGRWSARQRLRRATRESLTIP- MMAR_0048|M.marinum_M -------------------------MAIFGRRTARQRLRKAAQESLAIP- MUL_0047|M.ulcerans_Agy99 -------------------------MAIFGRRTARQRLRKAAQESLVIP- MAV_0048|M.avium_104 -------------------------MAIFGRMTARQRLRRATRESLSIP- Mflv_0752|M.gilvum_PYR-GCK MTSSTPGPIITRDMVLLDASVDGDKQAVIARLVAALASAGRTGEAAGLVG *::.* * : *: : Mb0030|M.bovis_AF2122/97 -TFSSSLDCTTRVIGGLWPAELSSNTAETATL------------AEHLKA Rv0029|M.tuberculosis_H37Rv -TFSSSLDCTTRVIGGLWPAELSSNTAETATL------------AEHLKA MMAR_0048|M.marinum_M -AFSSPPDCTPWVIGGLWPTELSRDAPETATL------------AEYLEA MUL_0047|M.ulcerans_Agy99 -AFSSPPDCTPWVIGGLWPTELSRDAPETATL------------AEYLEA MAV_0048|M.avium_104 -AFSSPVDCTPWVTGGLWPAELSTVTPETATL------------AEYLKA Mflv_0752|M.gilvum_PYR-GCK AAMAREEQSATGLPGGIAIPHCRSPYVDTPTIGFARLKPAVDFGAPDGPA ::: :.:. : **: .. :*.*: * * Mb0030|M.bovis_AF2122/97 DLHRIVGSAN----DELMVIWRAGMADSTRRAEEDRVIDRARASAMRRVE Rv0029|M.tuberculosis_H37Rv DLHRIVGSAN----DELMVIWRAGMADSTRRAEEDRVIDRARASAMRRVE MMAR_0048|M.marinum_M DLQRIADSAN----EELASLRHAVMLDSDRRAAEARVIDDARARAVQRVE MUL_0047|M.ulcerans_Agy99 DLQRIADSAN----EELASLRHAVMLDSDRRAAEARVIDEARARAVQRIE MAV_0048|M.avium_104 DLQRIADGAN----DELRKLKRAGMTDTARQAAEARVIEQARTRAVRRVE Mflv_0752|M.gilvum_PYR-GCK DLAFLIAAPDSGGQEHMKLLSSLARALVRKDFVESLRNAATADEVVDLVE ** : ..: :.: : : * : .: :* Mb0030|M.bovis_AF2122/97 SAMRELRQITGRVPVEIPR------------------------------- Rv0029|M.tuberculosis_H37Rv SAMRELRQITGRVPVEIPR------------------------------- MMAR_0048|M.marinum_M SARNQLREGASTEPPVAPP------------------------------- MUL_0047|M.ulcerans_Agy99 SARNQLREGASTEPPVAPR------------------------------- MAV_0048|M.avium_104 STIRYLHAVQSGARPPAPPRPTLDAPGADLERTQVLPAVGDAEHTAGPPA Mflv_0752|M.gilvum_PYR-GCK GVVNPAPVAPAAAAPAAAPAAAPPAAKTIVAITACPTGIAHTYMAADSLS .. . . . Mb0030|M.bovis_AF2122/97 -----------------------------------MRGAGGSDLDT---- Rv0029|M.tuberculosis_H37Rv -----------------------------------MRGAGGSDLDT---- MMAR_0048|M.marinum_M ----------------------------------DVADPNAAEPGS---- MUL_0047|M.ulcerans_Agy99 ----------------------------------DIADPNAGEPGS---- MAV_0048|M.avium_104 QQTPEARPRPTRRRAAEDEPAQLEETRVLPAIRDDAAAADASVPETPASE Mflv_0752|M.gilvum_PYR-GCK QAAKEAG-------------------------VTLVVETQGSSGSTPVPS . .. : Mb0030|M.bovis_AF2122/97 -------------------TRLMPAVTVVQPADQACTDWPVAA------- Rv0029|M.tuberculosis_H37Rv -------------------TRLMPAVTVVQPADQACTDWPVAA------- MMAR_0048|M.marinum_M -----------------QPQPPTAGRPDAVDAARAAARAPAPA------- MUL_0047|M.ulcerans_Agy99 -----------------QPQPPMAGRPDAVDAARAAARAPAPA------- MAV_0048|M.avium_104 TPVPEAPAAEAPVPEAPAPEAPAAEVPEAPAPEAPAAEVPEPLGEPTTRG Mflv_0752|M.gilvum_PYR-GCK DTIAKADAVIFATDVGVKDKGRFAGKPVVASGVKRAINEPAKMIAEAVAA . . . . * Mb0030|M.bovis_AF2122/97 ------------------------------------AED----------- Rv0029|M.tuberculosis_H37Rv ------------------------------------AED----------- MMAR_0048|M.marinum_M -----------------------------------------VPES----- MUL_0047|M.ulcerans_Agy99 -----------------------------------------VPES----- MAV_0048|M.avium_104 RHHAPVPEPVAERVEPDIAAPAEAADLEQTQVIPVVRRDEPVPEPPVVAP Mflv_0752|M.gilvum_PYR-GCK ADNPNAARVEGSGSAAPDAPSGNVGWGTRTRQILLTGVSYMIPFVAAGGL Mb0030|M.bovis_AF2122/97 -------------------------------------------------D Rv0029|M.tuberculosis_H37Rv -------------------------------------------------D MMAR_0048|M.marinum_M -------------------------------------------------D MUL_0047|M.ulcerans_Agy99 -------------------------------------------------D MAV_0048|M.avium_104 PEPAEEPADSGRHHAPADRDEPATEGRTAVADTDTAQPRVEKPAPTTVFD Mflv_0752|M.gilvum_PYR-GCK LIALGFLFGGYEIADSGNDIALNNSLTNLPDGGFLQYLGAILFTLGGLAF Mb0030|M.bovis_AF2122/97 EARLQRLLAFVARQEP-RLNWAVGVNADGTTVLVTDVAHGWIPPGIALPE Rv0029|M.tuberculosis_H37Rv EARLQRLLAFVARQEP-RLNWAVGVHADGTTVLVTDVAHGWIPPGIALPE MMAR_0048|M.marinum_M DQRLRRLLMFVARQEP-RLNWAIGQRPEG-TVLVTDVAHGWIPPGIALPQ MUL_0047|M.ulcerans_Agy99 DQRLRRLLMFVARQEP-RLNWAIGRQSEG-TVLVTDVAHGWIPPGIALPQ MAV_0048|M.avium_104 NNRLNRLLEFVVRQEP-RLNWAIGDRADGTTILVTDLAHGWIPSGIALPA Mflv_0752|M.gilvum_PYR-GCK SFLVPALAGYISFAIADRPGLAPGFTAGALAVFVGGGFIGGIVGGVIAGF . : * :: . * . * * . . :::* . * * *: Mb0030|M.bovis_AF2122/97 GVRLLAPARRAGRAPELVGITTC----------CKTYTPGDSLRRAVDST Rv0029|M.tuberculosis_H37Rv GVRLLAPARRAGRAPELVGITTC----------CKTYTPGDSLRRAVDST MMAR_0048|M.marinum_M GVRLLPPKRRSGRLAALVDAATG----------LLSYSPGDPLPWADEDT MUL_0047|M.ulcerans_Agy99 GVRLLPPKRRSGRLAALVDAATG----------SLSYSPGDPLPWVDEDT MAV_0048|M.avium_104 GVRLLEPERRSGDVVALIGETVR----------RVTYTPGDTLRRSADFA Mflv_0752|M.gilvum_PYR-GCK AALWISNIKTPAWLRGLMPVVIIPLIASLAVGLIMFFLIGRPLALINTGL .. : : .. *: . : * .* Mb0030|M.bovis_AF2122/97 APTSSVQPRALPAIAGLSVELGIATQRHDGLPKIVHAMATAAGNG--AAA Rv0029|M.tuberculosis_H37Rv APTSSVQPRALPAIAGLSVELGIATQRHDGLPKIVHAMATAAGNG--AAA MMAR_0048|M.marinum_M ATRSSVRPRELPMADNVARELCDATRSRVGLPRRAHVLAKAADAGTAVVE MUL_0047|M.ulcerans_Agy99 ATRSSVRPRELPMADNVARELCDATRSRVGLPRMAHVLAKAADAGTAVVE MAV_0048|M.avium_104 ATQSSSQPRELPPIDDLATAISRAIRGRAGLPKIVPRLADAAAAGAVIVD Mflv_0752|M.gilvum_PYR-GCK TNWLNSLTGTSAVLLGVILGLMMCFDLGGPVNKAAYAFATAGLAAATTGS : . . . .: : . : : . :* *. . Mb0030|M.bovis_AF2122/97 EEVDLLRVHVDTALHHVLAQYPRVDPALLLN------------------- Rv0029|M.tuberculosis_H37Rv EEVDLLRVHVDTALHHVLAQYPRVDPALLLN------------------- MMAR_0048|M.marinum_M DEIDLLRVHLDTARHEVVAHYPSIDGEVLLN------------------- MUL_0047|M.ulcerans_Agy99 DEIDLLRVHLDTARHQIVAHYPSIDGEVLLN------------------- MAV_0048|M.avium_104 QEVDVLRVHLDTARYQLLVQYPNVNPALLLK------------------- Mflv_0752|M.gilvum_PYR-GCK FQIMAAVMAAGMVPPLAMALATTIRPGLFSEPERENGRAAWLLGASFISE :: : . . :. . : :: : Mb0030|M.bovis_AF2122/97 -------CMLLAATERSVTGDPIAANYHFAWFRELDSRR----------- Rv0029|M.tuberculosis_H37Rv -------CMLLAATERSVTGDPIAANYHFAWFRELDSRR----------- MMAR_0048|M.marinum_M -------CMLLAATASSVSGDAVTANYHLAWFRELNA------------- MUL_0047|M.ulcerans_Agy99 -------WMLLAATASSVNGDAVTANYHLAWFRELKA------------- MAV_0048|M.avium_104 -------CLLMATTEGIASGDPVSANYHLAWYRTLAAPSPGG-------- Mflv_0752|M.gilvum_PYR-GCK GAIPFAAADPLRVIPSMMFGGAITGALCMAFGVTLRAPHGGIFVFFAIGN : . *..::. :*: * : Mb0030|M.bovis_AF2122/97 --------------------------------------- Rv0029|M.tuberculosis_H37Rv --------------------------------------- MMAR_0048|M.marinum_M --------------------------------------- MUL_0047|M.ulcerans_Agy99 --------------------------------------- MAV_0048|M.avium_104 --------------------------------------- Mflv_0752|M.gilvum_PYR-GCK LLWFVIALVVGTVVAGLTVVAAKQFIKPADRTDADLVAA