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TQPIITDDLVLLDVDAGSDKEAVIARLAGALGGAGRASDTAGLVGAAMAREAQSATGLPGGIAIPHCRSP YVDTATIGFARLDPKVDFGAPDGPADLAFLIAAPESGGSEHMKLLSSLARALVRKDFVESLRSASSTQEV VELVNSAVKPAAAPPASAPKPAAEPKPAADKSVSIVAVTSCPTGIAHTYMAADALKAAAEKAGVACTVET QGSAGSTPLSAETIAAADAVIFATDVGVKDRQRFAGKPVIASGVKRAINEPDKMVAEAISAASDPGAPWV AGQAAESASAPAGDVGWGTRIRQILLTGVSYMIPFVAAGGLLIALGFLLAGYEIGNTPDGETQSLGNIIA THNSLTNLPSGGVAQYLGAVLFTLGGLAFSFLVPALAGYIAFAIADRPGIAPGFTAGAVAVFVGGGFIGG IVGGLIAGFAALWISRIGVPQWARGLMPVVVIPLFASMVVGLLMFLLLGRPLAALTSGLTNWLGGLSGGS AIALGVILGLMMCFDLGGPVNKAAYAFATASLVNPTQANLQIMAAVMAAGMVPPLAMALATVIRPRLFSE PERENGRAAWLLGASFITEGAIPFAAADPLRVIPSMMVGGAVTGATVMAAAVTLRAPHGGIFVFFAIGNL LWFVIAVALGTVVSALTVIAAKQFTKRPVTAPEAPALATT*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. smegmatis MC2 155 | MSMEG_0085 | - | - | 100% (671) | PTS system, Fru family protein, IIABC components |
| M. smegmatis MC2 155 | MSMEG_4559 | - | 4e-05 | 28.31% (272) | ABC transporter, membrane spanning protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2355 | PE23 | 0.0001 | 26.19% (336) | PE family protein |
| M. gilvum PYR-GCK | Mflv_0752 | - | 0.0 | 75.23% (666) | PTS system, fructose subfamily, IIC subunit |
| M. tuberculosis H37Rv | - | - | - | - | - |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | - | - | - | - | - |
| M. marinum M | MMAR_2104 | speE | 5e-05 | 26.60% (203) | spermidine synthase, SpeE |
| M. avium 104 | MAV_3084 | amt | 1e-05 | 24.76% (416) | ammonium transporter |
| M. thermoresistible (build 8) | - | - | - | - | - |
| M. ulcerans Agy99 | - | - | - | - | - |
| M. vanbaalenii PYR-1 | Mvan_0094 | - | 0.0 | 76.09% (665) | PTS system, fructose subfamily, IIC subunit |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_0752|M.gilvum_PYR-GCK MTSSTPGPIITRDMVLLDASVDGDKQAVIARLVAALASAGRTGEAAGLVG
Mvan_0094|M.vanbaalenii_PYR-1 MTSST-APIITRDLVLLDVAIDGDKQAVIARLVNALAAAGRTDDADGLIG
MSMEG_0085|M.smegmatis_MC2_155 ----MTQPIITDDLVLLDVDAGSDKEAVIARLAGALGGAGRASDTAGLVG
Mb2355|M.bovis_AF2122/97 ---------------------------------------------MQFLS
MAV_3084|M.avium_104 --------------------------------------------------
MMAR_2104|M.marinum_M ----------MTATDHAPAPDTVGTVTASGRWRALLLAAVAACAACGIIY
Mflv_0752|M.gilvum_PYR-GCK AAMAREEQSATGLPGGIAIPHCRSPYVDTPTIGFARLKPAVDFGAPDGPA
Mvan_0094|M.vanbaalenii_PYR-1 AAMAREEQSATGLPGGIAIPHCRSPYVDTPTIGFARLTPGVDFGAPDGPA
MSMEG_0085|M.smegmatis_MC2_155 AAMAREAQSATGLPGGIAIPHCRSPYVDTATIGFARLDPKVDFGAPDGPA
Mb2355|M.bovis_AF2122/97 VIPEQVESAAQDLAG-------------------IRSALSASYAAAAGPT
MAV_3084|M.avium_104 --MHGIDPAAT-----------------------AWLLASTALVLLMTPG
MMAR_2104|M.marinum_M ELALLTLSTSLDGGGIVATSLIVAGYIAALGAGALLVKPLLAHAAIAFIA
::
Mflv_0752|M.gilvum_PYR-GCK DLAFLIAAPDSGGQEHMKLLSSLARALVRKDFVESLRNAATADEVVDLVE
Mvan_0094|M.vanbaalenii_PYR-1 DLAFLIAAPDSGGQEHMKLLSSLARALVRKDFVESLRNAGSADEVVALVE
MSMEG_0085|M.smegmatis_MC2_155 DLAFLIAAPESGGSEHMKLLSSLARALVRKDFVESLRSASSTQEVVELVN
Mb2355|M.bovis_AF2122/97 TAVVSAAEDEVS-----TAIASIFGAYGRQCQVLSAQASAFHDEFVNLLK
MAV_3084|M.avium_104 LAIFYGGMVRTTGVLNMIMMSFISIPLVTVAWLLVGYTMAFSQDGMSGLV
MMAR_2104|M.marinum_M VEVLLGIIGGLSAAALYVAFAFIDGSTWVLALGTALIGGLVGAEVPLLMT
. :: : . : :
Mflv_0752|M.gilvum_PYR-GCK GVVNPAPVAPAAAAPAAA-PAAAPPAAKTIVAITACPTGIAHTYMAADSL
Mvan_0094|M.vanbaalenii_PYR-1 GVVNPAPAAPPAP--------VEKPAAKTIVAITACPTGIAHTYMAADAL
MSMEG_0085|M.smegmatis_MC2_155 SAVKPAAAPPASAPKPAAEPKPAADKSVSIVAVTSCPTGIAHTYMAADAL
Mb2355|M.bovis_AF2122/97 TGATAYRNTEFAN-----------AQSNVLNAVNAPARSLLGHPSAAESV
MAV_3084|M.avium_104 GNLRHFGMLGITP----------------DTTHGAVPELLYATFQLTFAI
MMAR_2104|M.marinum_M LLQRGRLAEAADTG----------RTLANLNAADYLGALIGGLVWPFVLL
: : :
Mflv_0752|M.gilvum_PYR-GCK SQAAKEAGVTLVVETQGSSGSTPVPSDTIAKADAVIFATDVGVKDKGRFA
Mvan_0094|M.vanbaalenii_PYR-1 AAAAKEAGVTLVVETQGSSGSTPLPSDTIAGADAVIFATDVGVKDRGRFA
MSMEG_0085|M.smegmatis_MC2_155 KAAAEKAGVACTVETQGSAGSTPLSAETIAAADAVIFATDVGVKDRQRFA
Mb2355|M.bovis_AF2122/97 QNSAPTLGGGHSTVTAGLAAQAGRAVATVEQQAAAAVAPLPSAG-----A
MAV_3084|M.avium_104 ITAALVSG--AIADRAKFAAWMVFVPVWTVAVYSVVAHWVWGPGGWLARL
MMAR_2104|M.marinum_M PHLGMIRGAAATGIVNLVAAAVVSIFLLRQVVSTRQLAMALSSLLAALGL
. * :. : .
Mflv_0752|M.gilvum_PYR-GCK GKPVVASGVKRAINEPAKMIAEAVAAADNPNAARVEGSGSAAPDAPSGNV
Mvan_0094|M.vanbaalenii_PYR-1 GKPVVASGVKRAINEPAKMIAEAVAAADNPNAPRVEGSGAAASEAPSGDV
MSMEG_0085|M.smegmatis_MC2_155 GKPVIASGVKRAINEPDKMVAEAISAASDPGAPWVAGQAAESASAPAGDV
Mb2355|M.bovis_AF2122/97 GLAQVVNGVVTAGQGSAAKLATALQSA----APWLAKSGGEFIVAG----
MAV_3084|M.avium_104 GVLDYAGGLVVEIVSGSSALALALVLG-----PRIGFKKDAMRPHN----
MMAR_2104|M.marinum_M LVTLLVHARDIETTSRQELYADPIIAYRHTSYQEIVVTRRGNDLRLYLDG
. . * .: :
Mflv_0752|M.gilvum_PYR-GCK GWGTRTRQILLTGVSYMIPFVAAGGLLIALGFLFGGYEIADS--------
Mvan_0094|M.vanbaalenii_PYR-1 GWGTRTRQILLTGVSYMIPFVAAGGLLIALGFLFAGYEIADT--------
MSMEG_0085|M.smegmatis_MC2_155 GWGTRIRQILLTGVSYMIPFVAAGGLLIALGFLLAGYEIGNTPDGETQSL
Mb2355|M.bovis_AF2122/97 -------QSALTGVALLQPAVVG---------------------------
MAV_3084|M.avium_104 ------LPLLFVGVGLLWFGWFG---------------------------
MMAR_2104|M.marinum_M GLQFSTRDEYRYTESLVYPALGDG--------------------------
. :
Mflv_0752|M.gilvum_PYR-GCK GNDIALNNSLTNLPDGGFLQYLGAILFTLGGLAFSFLVPALAGYISFAIA
Mvan_0094|M.vanbaalenii_PYR-1 GNDIALNNSLTNLPPGGFLEYLGAILFSLGGLAFGFLVPALAGYISFAIA
MSMEG_0085|M.smegmatis_MC2_155 GNIIATHNSLTNLPSGGVAQYLGAVLFTLGGLAFSFLVPALAGYIAFAIA
Mb2355|M.bovis_AF2122/97 -----VVQAGGTFLTAGTSAATGLGLLTLAGVEFSQGVGNLA--------
MAV_3084|M.avium_104 ------FNAGSALAANGTAAAIFLNTLVAG--CLGMLGWLSVEQIRDGRP
MMAR_2104|M.marinum_M --------ARSVLVLGGGDGLAARELLRLPRIERIVQVELDPAVIELART
: : * :
Mflv_0752|M.gilvum_PYR-GCK DRPGLAPGFTAGALAVFVGGGFI---GGIVGGVIAGFAALWISNIKTPAW
Mvan_0094|M.vanbaalenii_PYR-1 DRPGIAPGFTAGALAVFIGGGFI---GGIVGGVLAGFAALWISNLKVPQW
MSMEG_0085|M.smegmatis_MC2_155 DRPGIAPGFTAGAVAVFVGGGFI---GGIVGGLIAGFAALWISRIGVPQW
Mb2355|M.bovis_AF2122/97 ----LASGTAATGLGLLGSAG------------VQLFSPAFLLAVPTALG
MAV_3084|M.avium_104 TTFGAASGVVAGLVAITPSCGTVNTLGATVVGLAAGVVCSFAVGAKLRFN
MMAR_2104|M.marinum_M TMREANGGALDDPRVQVVIGDAMKWLRGTDSGQSRRFDAVIVDLPDPDTP
* . .
Mflv_0752|M.gilvum_PYR-GCK LRGLMPVVIIPLIASLAVGLIMFFLIGRPLALINTGLTN---WLNSLTGT
Mvan_0094|M.vanbaalenii_PYR-1 FRGLMPVVIVPLGASLFVGLIMFFLVGRPLALINSGLTN---WLSGLSGT
MSMEG_0085|M.smegmatis_MC2_155 ARGLMPVVVIPLFASMVVGLLMFLLLGRPLAALTSGLTN---WLGGLSGG
Mb2355|M.bovis_AF2122/97 GVGSLAIAVVQLVQGVQHLSLVVPNVVAGIAALQTAGAQ---FAQGVNHT
MAV_3084|M.avium_104 YDDSLDVVGVHFVGGVVGVSLIGLFATAVMTAGPQGLFYGGGVAQLGKQA
MMAR_2104|M.marinum_M ALGRLYSAEFYALAAHALAPDGLMVVQAGSPFSTPTAFWR--TVSTIKAA
. : . . . . .
Mflv_0752|M.gilvum_PYR-GCK SAVLLGVILGLMMCFDLGGPVNKAAYAFATAGLAAATTGSFQIMAAVMAA
Mvan_0094|M.vanbaalenii_PYR-1 SAIFLGIILGLMMCFDLGGPVNKAAYAFATAGLAAETTASFEIMAAVMAA
MSMEG_0085|M.smegmatis_MC2_155 SAIALGVILGLMMCFDLGGPVNKAAYAFATASLVNPTQANLQIMAAVMAA
Mb2355|M.bovis_AF2122/97 MLAAQLGAPGIAVLQTAGG-----HFAQGIGHLTTAGNAAVTVLIS----
MAV_3084|M.avium_104 LAIAAVALYAFTVSFLLAKAIDRVMGFRVSAEDETTGVDLTQHAETAYAE
MMAR_2104|M.marinum_M GYAVTPYHVHVPTFGDWGFALARRGGTAPIPAVPADAPSLRFLNQPVLNA
. . .
Mflv_0752|M.gilvum_PYR-GCK GMVPPLAMALATTIRPGLFSEPERENGRAAWLLGASFISEGAIPFAAADP
Mvan_0094|M.vanbaalenii_PYR-1 GMVPPLAMALATTIRPGLFSEPERENGRAAWLLGASFISEGAIPFAAADP
MSMEG_0085|M.smegmatis_MC2_155 GMVPPLAMALATVIRPRLFSEPERENGRAAWLLGASFITEGAIPFAAADP
Mb2355|M.bovis_AF2122/97 --------------------------------------------------
MAV_3084|M.avium_104 GVHG---------------HLPQRRPGPGDRLK-----------------
MMAR_2104|M.marinum_M ATVFSSDVGPTMLEPSTLDNPRIVEDMRRGYR------------------
Mflv_0752|M.gilvum_PYR-GCK LRVIPSMMFGGAITGALCMAFGVTLRAPHGGIFVFFAIGNLLWFVIALVV
Mvan_0094|M.vanbaalenii_PYR-1 LRVIPSMMFGGAITGALCMAFGATSRAPHGGIFVLFAIDNKLGFVIALVA
MSMEG_0085|M.smegmatis_MC2_155 LRVIPSMMVGGAVTGATVMAAAVTLRAPHGGIFVFFAIGNLLWFVIAVAL
Mb2355|M.bovis_AF2122/97 --------------------------------------------------
MAV_3084|M.avium_104 --------------------------------------------------
MMAR_2104|M.marinum_M --------------------------------------------------
Mflv_0752|M.gilvum_PYR-GCK GTVVAGLTVVAAKQFIK--PADRTDADLVAA
Mvan_0094|M.vanbaalenii_PYR-1 GTVAAALAVVAAKQFIK--AGAKTEPELVTA
MSMEG_0085|M.smegmatis_MC2_155 GTVVSALTVIAAKQFTKRPVTAPEAPALATT
Mb2355|M.bovis_AF2122/97 -------------------------------
MAV_3084|M.avium_104 -------------------------------
MMAR_2104|M.marinum_M -------------------------------