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VPSFRRRDSVIEADRVEESTVDPEGVPAGDRARALADVAEAEAAEAEAMAAAARARARAAKLRQEALAAA ADSDGETARTDAVASTTEATDDADDAELLDIDDDRDDDLDGDETDAVGEAESPTRKRLLRRPGWASVGVA LVLVIAVLGTAALLAVSGYMRLEHRDAENLRQQNAEYAAAARQSVVTLMSLDFNKAEEDVQRIIDNSTGQ FKDDFESQAAEFVKVAQDSKVVTEVTVNSTAVERMTGDGAEVLVAASSRVTNTAGADQEPRTWRLSVSLV REDGQIKMSKVEFVP
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. gilvum PYR-GCK | Mflv_2526 | - | - | 100% (295) | hypothetical protein Mflv_2526 |
| M. gilvum PYR-GCK | Mflv_4529 | - | 7e-36 | 43.65% (181) | hypothetical protein Mflv_4529 |
| M. gilvum PYR-GCK | Mflv_2107 | - | 1e-30 | 31.56% (225) | hypothetical protein Mflv_2107 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1398c | - | 2e-60 | 48.74% (277) | hypothetical protein Mb1398c |
| M. tuberculosis H37Rv | Rv1363c | - | 1e-60 | 48.74% (277) | hypothetical protein Rv1363c |
| M. leprae Br4923 | MLBr_02595 | - | 2e-10 | 30.23% (172) | hypothetical protein MLBr_02595 |
| M. abscessus ATCC 19977 | MAB_4593c | - | 8e-17 | 27.64% (246) | hypothetical protein MAB_4593c |
| M. marinum M | MMAR_4687 | - | 2e-55 | 46.05% (291) | hypothetical protein MMAR_4687 |
| M. avium 104 | MAV_0938 | - | 2e-62 | 47.77% (291) | hypothetical protein MAV_0938 |
| M. smegmatis MC2 155 | MSMEG_4771 | - | 2e-62 | 46.75% (308) | hypothetical protein MSMEG_4771 |
| M. thermoresistible (build 8) | TH_0392 | - | 2e-51 | 57.61% (184) | POSSIBLE MEMBRANE PROTEIN |
| M. ulcerans Agy99 | MUL_0306 | - | 2e-55 | 46.39% (291) | hypothetical protein MUL_0306 |
| M. vanbaalenii PYR-1 | Mvan_4132 | - | 1e-101 | 66.45% (304) | hypothetical protein Mvan_4132 |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_2526|M.gilvum_PYR-GCK ---------MPSFRRRDSVIEADRVEESTVDPEGVPAGDRAR----ALAD
Mvan_4132|M.vanbaalenii_PYR-1 ---------MPSFRRRDAVIDADRVEESTVEPESVTEADQAR----ALAE
MSMEG_4771|M.smegmatis_MC2_155 ---------MPSRKPTLPVINGSHGDDQDADRSDSPAGELSADDALLLAE
TH_0392|M.thermoresistible__bu ----------VHWRPXX---------XAAPDSSDTTP-------------
Mb1398c|M.bovis_AF2122/97 --------MAETTEPPS---------DAGTSQADAMAL------------
Rv1363c|M.tuberculosis_H37Rv --------MAETTEPPS---------DAGTSQADAMAL------------
MAV_0938|M.avium_104 --------MADAKKPPH---------DSATSDEDVKALL----------E
MMAR_4687|M.marinum_M MHAALLSGGCGVSTGIGNGAADSRSAPVDEDEIGGTAAEMR-----ALAE
MUL_0306|M.ulcerans_Agy99 ---------------------------MDEDEIGGTAAEMR-----ALAD
MAB_4593c|M.abscessus_ATCC_199 --------MADDAADKD---------AKNADESAVTSD----------AE
MLBr_02595|M.leprae_Br4923 --------------------------------------------------
Mflv_2526|M.gilvum_PYR-GCK VAEAEAAEAEAMAAAARARARAAKLRQEAL--AAAADSDGETARTDAVAS
Mvan_4132|M.vanbaalenii_PYR-1 EAEAEAAEAEAMAAAAKARARAARLRRQAL--AADVAAKPEVGEDSATVG
MSMEG_4771|M.smegmatis_MC2_155 QAEAEAAEAEAIAAAARARAEALRLRRQAE--EAAKRSSE--ADAENESV
TH_0392|M.thermoresistible__bu ------------AAGARRR---FRLR------------------------
Mb1398c|M.bovis_AF2122/97 AAEAEAAEAEALAAAARARARAARLKREAL--AMAP-------------A
Rv1363c|M.tuberculosis_H37Rv AAEAEAAEAEALAAAARARARAARLKREAL--AMAP-------------A
MAV_0938|M.avium_104 EAEAEAAEAEALAAAARARARAARLRREAQ--AQAAKAAAETSEADEHAA
MMAR_4687|M.marinum_M EAEAEAAEAEALAAAAGARARALQLRRRAERAEAAAEVDAACEATHEGAA
MUL_0306|M.ulcerans_Agy99 EAEAEAAEAEAVAAAAGARARALQLRRRAERAEAAAEVDAACEATHEGAA
MAB_4593c|M.abscessus_ATCC_199 KAESSAPSSAAVESTAEGTTEAATAEVADF--------------------
MLBr_02595|M.leprae_Br4923 -----MPESQVAADDSGVTLNRSRLGRG----------------------
:
Mflv_2526|M.gilvum_PYR-GCK TTEATDDAD--------DAELLDID-DDRDDDLDGDETDAVGEAES----
Mvan_4132|M.vanbaalenii_PYR-1 DADVDGDDDAVTGSADAEPEVVDIETAETDETAETDDSAPADGGAA----
MSMEG_4771|M.smegmatis_MC2_155 DESETGEPED-------AENAEDTEDTEAAEDTEAAEKDSAGKPE-----
TH_0392|M.thermoresistible__bu --------------------------------------------------
Mb1398c|M.bovis_AF2122/97 EDE--NVPEE-------YADWEDAEDYDDYDDYEAADQEAARSAS-----
Rv1363c|M.tuberculosis_H37Rv EDE--NVPEE-------YADWEDAEDYDDYDDYEAADQEAARSAS-----
MAV_0938|M.avium_104 DDEPAETDDE-------VSDSVEATDADDTETTQAQTKEAAKEAEPNEEA
MMAR_4687|M.marinum_M DGQATASHNGAEEPSANSADVLESDDVAETEELSADDDEPAAAGSAEADE
MUL_0306|M.ulcerans_Agy99 DGQATASRNGAEEPTGNSADVLESDDVAETEELRADDDEPVAAGSAKADE
MAB_4593c|M.abscessus_ATCC_199 -------------------DAEDSEKTKDSGAVEDSDDEDISLEPD----
MLBr_02595|M.leprae_Br4923 --------------------------------------------------
Mflv_2526|M.gilvum_PYR-GCK -------------PTRKRLLRRPGWASVGVALVLVIAVLGTAALLAVSGY
Mvan_4132|M.vanbaalenii_PYR-1 -------------PSRRRRIPRPGWK----AAVATVVALATVALLGASGY
MSMEG_4771|M.smegmatis_MC2_155 ----AQEAQELPEAKLTTRTNAPVWKWIAAGVTVVIILG----LLTVSGL
TH_0392|M.thermoresistible__bu ------------------------WGIVARAAAIVAICL----LLAASGY
Mb1398c|M.bovis_AF2122/97 -------------WRRRLRVRLPRLSTIAMAAAVVIICG----FTGLSGY
Rv1363c|M.tuberculosis_H37Rv -------------WRRRLRVRLPRLSTIAMAAAVVIICG----FTGLSGY
MAV_0938|M.avium_104 AEETAEDAESESKARSRRRLRLPSWSVAWKAAVIALICA----FVAASGY
MMAR_4687|M.marinum_M SE--ADELADESERSRRGLLRRPKLSTLTAALAVLVILA----ALAGSAY
MUL_0306|M.ulcerans_Agy99 SE--ADELADESERSRRGLLRRPKLSTLTAALAVLVILA----ALAGSAY
MAB_4593c|M.abscessus_ATCC_199 ------------EEENPKRIRGRHWALTAAAIVAIAIVA-------LAAI
MLBr_02595|M.leprae_Br4923 ------------------------WLTGIAVALLLAGCG----IGTGGYC
.
Mflv_2526|M.gilvum_PYR-GCK MRLEHRDAENLRQQNAEYAAAARQSVVTLMSLDFNKAEEDVQRIIDNSTG
Mvan_4132|M.vanbaalenii_PYR-1 MVWTHRGAEKLRQQNAEYAAAARQSVVTLMSLDFNKAEEDVQRIIDNSTG
MSMEG_4771|M.smegmatis_MC2_155 MMYHHKQMQDDQRRAAEFAAAARQGVVTLMSLDHTHAKEDVQRIIDMSTG
TH_0392|M.thermoresistible__bu MVWYHQQVEAEKQRAAEFAAAARQGIVSLMSLDFNRAEEDVQRIIDNSTG
Mb1398c|M.bovis_AF2122/97 IVWQHHEATERQQRAAAFAAGAKQGVINMNSLDFNKAKEDVARVIDSSTG
Rv1363c|M.tuberculosis_H37Rv IVWQHHEATERQQRAAAFAAGAKQGVINMTSLDFNKAKEDVARVIDSSTG
MAV_0938|M.avium_104 MMWERHQTSERNQRIANFLAAARQGVVNMTSLDFNKAKEDVQRVIDSSTG
MMAR_4687|M.marinum_M MVLQHRDATRQRERVAEFAAAARQGVITLTSLDFQDAKQGIGRILDNSTG
MUL_0306|M.ulcerans_Agy99 MVLQHRDATRQRERVAEFAAAARQGVITLTSLDFQDAKQGIGRILDNSTG
MAB_4593c|M.abscessus_ATCC_199 IGRLYEEQRIEEQSSREALAAAQEFANVMINVDSAKLDESSNKTLERSTG
MLBr_02595|M.leprae_Br4923 MLRYHQDSQAMARNDNAALKTALDCVAATQAPDTNTMAASEQKIIDCGTD
: . . * : * . : :: .*.
Mflv_2526|M.gilvum_PYR-GCK QFKDDFESQAAEFVKVAQDSKVVTEVTVNSTAVER--MTGDGAEVLVAAS
Mvan_4132|M.vanbaalenii_PYR-1 QFKTDFESQAADFVKVAQDSKVVTEVSVNSTAVES--MSDDSAEVLVAAS
MSMEG_4771|M.smegmatis_MC2_155 DFRADFEATAEDFAKVAEQAKVTTEAQVNATAVDS--MTDDSAVVLVAAT
TH_0392|M.thermoresistible__bu EFREEFESAAEDFATVAKESKVITDVSVNATAVQS--MTEDSAEVLVAAT
Mb1398c|M.bovis_AF2122/97 EFRDDFQQRAADFTKVVEQSKVVTEGTVNATAVES--MNEHSAVVLVAAT
Rv1363c|M.tuberculosis_H37Rv EFRDDFQQRAADFTKVVEQSKVVTEGTVNATAVES--MNEHSAVVLVAAT
MAV_0938|M.avium_104 QFRDDFQQRAKDFTTVVEQSKVVTQGTVNAAAVQS--IDGNSALVLVAAT
MMAR_4687|M.marinum_M SFKDELLKSSDDFIQVVQQAQVVEQGTVQAVAVDRNSMTDDSAVVLVAST
MUL_0306|M.ulcerans_Agy99 SFKDELLKSSDDFIQVVQQAQVVEQGTVQAVAVDRNSMTDDSAVVLVAST
MAB_4593c|M.abscessus_ATCC_199 DFKQKYSESSTTLRQVMIENKAKATGVVVDSAVKS--AAPDKVEVLLFID
MLBr_02595|M.leprae_Br4923 AFHAQALLYTNMLVQAYQAANVHVQVSDMRAAVER-HNNDGSIDVLVALR
*: . : : . :. **. **:
Mflv_2526|M.gilvum_PYR-GCK SRVTNTAGADQEPRTWRLSVSLVREDGQIKMSKVEFVP-
Mvan_4132|M.vanbaalenii_PYR-1 SRVTNTAGANQEPRTWRLSVSLKREDGQIKMAKVEFVP-
MSMEG_4771|M.smegmatis_MC2_155 SRISNSAGADQDPRNWRLSVTVKQDGDQIKLAKVEFVP-
TH_0392|M.thermoresistible__bu SSITNEAGANQDPRSWRLFVSVTRDDGQLKMSKVEFVP-
Mb1398c|M.bovis_AF2122/97 SRVTNSAGAKDEPRAWRLKVTVTEEGGQYKMSKVEFVP-
Rv1363c|M.tuberculosis_H37Rv SRVTNSAGAKDEPRAWRLKVTVTEEGGQYKMSKVEFVP-
MAV_0938|M.avium_104 SRITNAAGAKDEPRNWRLKVTVTDEGGQYKMSKLEFVP-
MMAR_4687|M.marinum_M SEVTNAAGAKKDPRKYRLIVTITRDGDQLKMSKVEFVP-
MUL_0306|M.ulcerans_Agy99 SEVTNAAGAKKDPRKYRLIVTITRDGDQLKMSKVEFVP-
MAB_4593c|M.abscessus_ATCC_199 QAVSNVAIPDARMDRSRVQITMQKVDGRWLASDVELT--
MLBr_02595|M.leprae_Br4923 VKLSNDRAHNQETG-YRLRVKMALAEGQYKISKLDQVTK
::* . *: :.: .: :.:: .