For questions or suggestions e-mail us at: ioerger@cs.tamu.edu

M. gilvum PYR-GCK Mflv_0678 (-)

annotation: transposase, mutator type
coordinates: 698669 - 699904
length: 411

MTQDHSALLAQLDALRSADAGAVFAELIRAGLQQLIEAEATAAIGAGRYQRTDGRMVHRNGHRPKTVSTT
SGDIEVQIPKLRAGSFFPSLLERRRRIDKALHAVIMEAYVHGVSTRSVDDLVAAMGVESGVSKSEVSRIC
AGLDIEIEAFRTRSLAHTEFPYIFCDATFCKVRVGAHVVSQALVVATGVSIDGTREVLGTAVGDSESFEF
WREFLASLKARGLTGVHLVISDAHVGLKTAVAQQFTNSSWQRCRVHFMRNLHTAVAAKHAPAVTAAVKTI
FAHTDPVEVAAQWDRVADTLAPSFPKVAAMMGEAKTDVLAFTAFPRAHWQKIWSNNPIERLNKEIKRRAD
VVEIFPNPAAFLRLATAVVIEAHDEWQVTRRYLSDISMDELRVVIEKKHAAAALAKQHQIT
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. gilvum PYR-GCKMflv_0678--100% (411)transposase, mutator type
M. gilvum PYR-GCKMflv_3191-0.0100.00% (411) transposase, mutator type
M. gilvum PYR-GCKMflv_0688-3e-8646.11% (373) transposase, mutator type

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb3461c-1e-14692.09% (278) transposase
M. tuberculosis H37RvRv3431c-1e-14692.09% (278) hypothetical protein Rv3431c
M. leprae Br4923-----
M. abscessus ATCC 19977-----
M. marinum M-----
M. avium 104MAV_5116-1e-13057.88% (406) transposase, Mutator family protein
M. smegmatis MC2 155MSMEG_4154-1e-17791.42% (338) transposase, Mutator family protein
M. thermoresistible (build 8)TH_2000-0.095.36% (388) PROBABLE TRANSPOSASE
M. ulcerans Agy99MUL_4584-2e-3328.24% (347) transposase for IS2606
M. vanbaalenii PYR-1Mvan_0585-1e-13160.15% (389) transposase, mutator type

CLUSTAL 2.0.9 multiple sequence alignment


MAV_5116|M.avium_104                MVKRPRITTERNIAMALDQSALLEVLDALRT-------------------
Mvan_0585|M.vanbaalenii_PYR-1       --------------MALDQSALLEVLDALRT-------------------
Mflv_0678|M.gilvum_PYR-GCK          --------------MTQDHSALLAQLDALRS-------------------
TH_2000|M.thermoresistible__bu      --------------------------------------------------
Mb3461c|M.bovis_AF2122/97           --------------------------------------------------
Rv3431c|M.tuberculosis_H37Rv        --------------------------------------------------
MSMEG_4154|M.smegmatis_MC2_155      --------------MTQDHSALLAQLDALKS-------------------
MUL_4584|M.ulcerans_Agy99           -MMTKTVVAVQPSQNHEDEAGAVAAIDVPSSRDVDELEVARELVRQAREA
                                                                                      

MAV_5116|M.avium_104                ----ADAGERITQAAETIYQALIDAELTAFIGASPHERT-ETRSNQRNGS
Mvan_0585|M.vanbaalenii_PYR-1       ----ADAGERITQACEIVYQALIDAELTAKIGAALHERT-ETRSNQRNGS
Mflv_0678|M.gilvum_PYR-GCK          ----ADAGAVFAELIRAGLQQLIEAEATAAIGAGRYQRT-DGRMVHRNGH
TH_2000|M.thermoresistible__bu      ---------VFAELIRAGLQQLIEAEATAAIGAGRYERT-DGRTVHRNGH
Mb3461c|M.bovis_AF2122/97           ---------MFAELIRAGLQALIEAEATEAIGAGRYERS-DGRIVHRNGH
Rv3431c|M.tuberculosis_H37Rv        ---------MFAELIRAGLQALIEAEATEAIGAGRYERS-DGRIVHRNGH
MSMEG_4154|M.smegmatis_MC2_155      ----ADAGAVFAELIRAGLQALIEAEATEVIGAGRYQRT-DGRATHRNGH
MUL_4584|M.ulcerans_Agy99           GVGLTGPGGLLKAMTKTVIETALDEELSEHLGYDRHDRAGYGNGNSRNGT
                                              :    .   :  :: * :  :*   ::*:   .   *** 

MAV_5116|M.avium_104                RPRTLSTVAG-DLELRIPKLRTGSFFPALLERRRRVDQCLFAVVMEAYLH
Mvan_0585|M.vanbaalenii_PYR-1       RPRTLSTVAG-DLELRIPKLRSGSFFPALLERRRRVDQCLFAVVMEAYLH
Mflv_0678|M.gilvum_PYR-GCK          RPKTVSTTSG-DIEVQIPKLRAGSFFPSLLERRRRIDKALHAVIMEAYVH
TH_2000|M.thermoresistible__bu      RPKTVSTTSG-DIEVQIPKLRAGSFFPSLLERRRRIDRALHAVIMEAYVH
Mb3461c|M.bovis_AF2122/97           RPKTVSTTAG-DIEVQIPKLRAGSFFPSLLERRRRIDKALHAVIMEAYVH
Rv3431c|M.tuberculosis_H37Rv        RPKTVSTTAG-DIEVQIPKLRAGSFFPSLLERRRRIDKALHAVIMEAYVH
MSMEG_4154|M.smegmatis_MC2_155      RPKTVSTTAG-DVEVQIPKLRAGSFFPSLLERRRRIDRALHAVIMEAYVH
MUL_4584|M.ulcerans_Agy99           RSKTVLTDACGSIEIDVPRDRAGTFEPKIVEKRQRRLTDVDEVVLSLYAR
                                    *.:*: * :  .:*: :*: *:*:* * ::*:*:*    :  *::. * :

MAV_5116|M.avium_104                GTSTRKVDDLVKALGTDTGISKSEVSRICKDLDTEVAAFRDRPLGDQRFP
Mvan_0585|M.vanbaalenii_PYR-1       GTSTRKVDDLVKALGADSGISKSEVSRICKDLDTEVGAFRDRPLGEQRFP
Mflv_0678|M.gilvum_PYR-GCK          GVSTRSVDDLVAAMGVESGVSKSEVSRICAGLDIEIEAFRTRSLAHTEFP
TH_2000|M.thermoresistible__bu      GVSTRSVDDLVTAMGVGSGVSKSEVSRICAGLDEEIEAFRIRSLAHTQFP
Mb3461c|M.bovis_AF2122/97           GVSTRSVDDLVAAMGVQAGVSKSEVSRICAGLDTEIEAFRTRSLTHTEFP
Rv3431c|M.tuberculosis_H37Rv        GVSTRSVDDLVAAMGVQAGVSKSEVSRICAGLDTEIEAFRTRSLTHTEFP
MSMEG_4154|M.smegmatis_MC2_155      GVSTRSVDDLVAALGVGSGVSKSEVSRICAGLDKEIDAFRTRSLNHTSFP
MUL_4584|M.ulcerans_Agy99           GLTTGEISAHFAHI-YDAAVSKDTVSRITDRVLEEMTAWHTRPLER-VYA
                                    * :* .:.  .  :   :.:**. ****   :  *: *:: *.*    :.

MAV_5116|M.avium_104                YVFLDATYCKARVNHRVVSQAVVIATGVAADGRREVLGFEVG--DSEDGA
Mvan_0585|M.vanbaalenii_PYR-1       YVFLDATYCKARVNHRVVSQAVVIATGVAADGRREVLGFEVG--DSEDGA
Mflv_0678|M.gilvum_PYR-GCK          YIFCDATFCKVRVGAHVVSQALVVATGVSIDGTREVLGTAVG--DSESFE
TH_2000|M.thermoresistible__bu      YVFCDATFCKVRIGAHVVSQALVVATGVSIDGTREVLGTAVG--DSESFE
Mb3461c|M.bovis_AF2122/97           YVFCDATFCKVRVGAHVVSQALVVATGVSIDGTREVLGTAVG--DSESYE
Rv3431c|M.tuberculosis_H37Rv        YVFCDATFCKVRVGAHVVSQALVVATGVSIDGTREVLGTAVG--DSESYE
MSMEG_4154|M.smegmatis_MC2_155      YVFCDATFCKVRIGAHVVSQALVVATGVSIDGTREVLGTAVG--DSESFE
MUL_4584|M.ulcerans_Agy99           AVFIDALHVKIRD-GQVGPRPVYAAVGVDLAGHRDVLGMWAGEGDGESAK
                                     :* ** . * *   :* .:.:  *.**   * *:***  .*  *.*.  

MAV_5116|M.avium_104                FWTAFLRSLKSRGLAGVQLVISDAHAGLRSAIDAVLIGAAWQRCRVHFLR
Mvan_0585|M.vanbaalenii_PYR-1       FWTAFLRSLKSRGLAGVQLVISDAHAGLRAAIDAVLIGSAWQRCRVHFLR
Mflv_0678|M.gilvum_PYR-GCK          FWREFLASLKARGLTGVHLVISDAHVGLKTAVAQQFTNSSWQRCRVHFMR
TH_2000|M.thermoresistible__bu      FWREFLASLKARGLSGVHLVVSDAHAGLKAAVAQQFTNSSWQRCRVHFMR
Mb3461c|M.bovis_AF2122/97           FWREFLASLKARGLTGVHLVISDAHAGLKAAVAQQFSGASWQRCRVHFMR
Rv3431c|M.tuberculosis_H37Rv        FWREFLASLKARGLTGVHLVISDAHAGLKAAVAQQFSGASWQRCRVHFMR
MSMEG_4154|M.smegmatis_MC2_155      FWREFLASLKARGLSGVHLVISDAHAGLKAAVAQQFTGSSWQRCRVHFMR
MUL_4584|M.ulcerans_Agy99           YWLAVLTELKNRGVADIFFLVCDGLKGLPDSVSAVFPDTVVQTCIIHLIR
                                    :*  .* .** **::.: :::.*.  **  ::   : .:  * * :*::*

MAV_5116|M.avium_104                NVLAQVPKGSAEMVAAAIRTVFAQPDAEHVREQLDTIAGMLGRQFPKVET
Mvan_0585|M.vanbaalenii_PYR-1       NVLAQVPKGSAEMVAAAIRTIFAQPDAEHVREQLDTIAGMLGRQFPKVET
Mflv_0678|M.gilvum_PYR-GCK          NLHTAVAAKHAPAVTAAVKTIFAHTDPVEVAAQWDRVADTLAPSFPKVAA
TH_2000|M.thermoresistible__bu      NLHTAVAAKHAPAVTAAVKTIFAHTDPDEVAAQWDRVADTLAGSFPKVAA
Mb3461c|M.bovis_AF2122/97           NLYTAVAAKHAPAVTVAVKTIFAHTDPEEVGAQWDRVADPLCQP------
Rv3431c|M.tuberculosis_H37Rv        NLYTAVAAKHAPAVTVAVKTIFAHTDPEEVGAQWDRVADPLCQP------
MSMEG_4154|M.smegmatis_MC2_155      NLHGVVAAKHAPAVTAAVKTIFAHTDPVDVAAQWDQVADTLAASFPKVAA
MUL_4584|M.ulcerans_Agy99           GTFRYAGRQHHTAIARALKPIYTAVNAAAAAEALDAFDTEWGHRYPAAIR
                                    .    .       :: *::.:::  :.  .    * .             

MAV_5116|M.avium_104                MLREAAADITAFADFPVAHWKKIWSTNPLERLNKEIKRRTDVVGVFPNPA
Mvan_0585|M.vanbaalenii_PYR-1       MLREAAEDITAFADFPAAHWKKIWSTNPLERLNKEIKRRTDVVGVFPNPA
Mflv_0678|M.gilvum_PYR-GCK          MMGEAKTDVLAFTAFPRAHWQKIWSNNPIERLNKEIKRRADVVEIFPNPA
TH_2000|M.thermoresistible__bu      MMGEAKTDVLAFTAFPRAHWQKIWSNNPIERLNKEIKRRADVVEIFPNPA
Mb3461c|M.bovis_AF2122/97           --------------------------------------------------
Rv3431c|M.tuberculosis_H37Rv        --------------------------------------------------
MSMEG_4154|M.smegmatis_MC2_155      MMDEAKADVLAFTAFPRTHWQKIWSNNPIVIC-------SAAVSVFY---
MUL_4584|M.ulcerans_Agy99           LWRNAWNEFIPFLDYDTEIRKVICSTNAIESLNARYRRAIRARGHFPTEQ
                                                                                      

MAV_5116|M.avium_104                ALLRLAGSVLVEAHDEWQVADKRYLSETSLALLDVSD-QSAETIAPTAAL
Mvan_0585|M.vanbaalenii_PYR-1       ALLRLAGSVLVEAHDEWQVADKRYLSETSLALLDTGE-QDTQTVAPTAAL
Mflv_0678|M.gilvum_PYR-GCK          AFLRLATAVVIEAHDEWQVTRRYLSDISMDELRVVIEKKHAAAALAKQHQ
TH_2000|M.thermoresistible__bu      AFLRLATAVVIEAHDEWQVTRRYLSDVSMDELRIVIEKKHAAAALAKQHQ
Mb3461c|M.bovis_AF2122/97           --------------------------------------------------
Rv3431c|M.tuberculosis_H37Rv        --------------------------------------------------
MSMEG_4154|M.smegmatis_MC2_155      ---------VDHEGSEWSVLR-SGCGYLQPSMKQILEGRCACCEGGFTAL
MUL_4584|M.ulcerans_Agy99           SALKCLYLVTRSLDPTGTGQKRWTMRWKPALNAFAITFADRMPGSETT--
                                                                                      

MAV_5116|M.avium_104                TA
Mvan_0585|M.vanbaalenii_PYR-1       TA
Mflv_0678|M.gilvum_PYR-GCK          IT
TH_2000|M.thermoresistible__bu      IA
Mb3461c|M.bovis_AF2122/97           --
Rv3431c|M.tuberculosis_H37Rv        --
MSMEG_4154|M.smegmatis_MC2_155      VA
MUL_4584|M.ulcerans_Agy99           --