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MTQDHSALLAQLDALKSADAGAVFAELIRAGLQALIEAEATEVIGAGRYQRTDGRATHRNGHRPKTVSTT AGDVEVQIPKLRAGSFFPSLLERRRRIDRALHAVIMEAYVHGVSTRSVDDLVAALGVGSGVSKSEVSRIC AGLDKEIDAFRTRSLNHTSFPYVFCDATFCKVRIGAHVVSQALVVATGVSIDGTREVLGTAVGDSESFEF WREFLASLKARGLSGVHLVISDAHAGLKAAVAQQFTGSSWQRCRVHFMRNLHGVVAAKHAPAVTAAVKTI FAHTDPVDVAAQWDQVADTLAASFPKVAAMMDEAKADVLAFTAFPRTHWQKIWSNNPIVICSAAVSVFYV DHEGSEWSVLRSGCGYLQPSMKQILEGRCACCEGGFTALVA
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. smegmatis MC2 155 | MSMEG_4154 | - | - | 100% (391) | transposase, Mutator family protein |
| M. smegmatis MC2 155 | MSMEG_4159 | - | 1e-31 | 29.51% (349) | IS6120, transposase |
| M. smegmatis MC2 155 | MSMEG_1731 | - | 1e-31 | 29.51% (349) | IS6120, transposase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3461c | - | 1e-143 | 89.93% (278) | transposase |
| M. gilvum PYR-GCK | Mflv_3191 | - | 1e-177 | 91.42% (338) | transposase, mutator type |
| M. tuberculosis H37Rv | Rv3431c | - | 1e-143 | 89.93% (278) | hypothetical protein Rv3431c |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | - | - | - | - | - |
| M. marinum M | - | - | - | - | - |
| M. avium 104 | MAV_5116 | - | 1e-109 | 58.28% (338) | transposase, Mutator family protein |
| M. thermoresistible (build 8) | TH_2000 | - | 1e-167 | 91.77% (316) | PROBABLE TRANSPOSASE |
| M. ulcerans Agy99 | MUL_4531 | - | 1e-32 | 29.19% (322) | transposase for IS2606 |
| M. vanbaalenii PYR-1 | Mvan_0585 | - | 1e-110 | 59.17% (338) | transposase, mutator type |
CLUSTAL 2.0.9 multiple sequence alignment
MAV_5116|M.avium_104 MVKRPRITTERNIAMALDQSALLEVLDALRT-------------------
Mvan_0585|M.vanbaalenii_PYR-1 --------------MALDQSALLEVLDALRT-------------------
Mflv_3191|M.gilvum_PYR-GCK --------------MTQDHSALLAQLDALRS-------------------
TH_2000|M.thermoresistible__bu --------------------------------------------------
Mb3461c|M.bovis_AF2122/97 --------------------------------------------------
Rv3431c|M.tuberculosis_H37Rv --------------------------------------------------
MSMEG_4154|M.smegmatis_MC2_155 --------------MTQDHSALLAQLDALKS-------------------
MUL_4531|M.ulcerans_Agy99 -MMTKTVVAVQPSQNHEDEAGAVAAIDVPSSRDVDELEVARELVRQAREA
MAV_5116|M.avium_104 ----ADAGERITQAAETIYQALIDAELTAFIGASPHERT-ETRSNQRNGS
Mvan_0585|M.vanbaalenii_PYR-1 ----ADAGERITQACEIVYQALIDAELTAKIGAALHERT-ETRSNQRNGS
Mflv_3191|M.gilvum_PYR-GCK ----ADAGAVFAELIRAGLQQLIEAEATAAIGAGRYQRT-DGRMVHRNGH
TH_2000|M.thermoresistible__bu ---------VFAELIRAGLQQLIEAEATAAIGAGRYERT-DGRTVHRNGH
Mb3461c|M.bovis_AF2122/97 ---------MFAELIRAGLQALIEAEATEAIGAGRYERS-DGRIVHRNGH
Rv3431c|M.tuberculosis_H37Rv ---------MFAELIRAGLQALIEAEATEAIGAGRYERS-DGRIVHRNGH
MSMEG_4154|M.smegmatis_MC2_155 ----ADAGAVFAELIRAGLQALIEAEATEVIGAGRYQRT-DGRATHRNGH
MUL_4531|M.ulcerans_Agy99 GVGLTGPGGLLKAMTKTVIETALDEELSEHLGYDRHDRAGYGSGNSRNGT
: . : :: * : :* ::*: ***
MAV_5116|M.avium_104 RPRTLSTVAG-DLELRIPKLRTGSFFPALLERRRRVDQCLFAVVMEAYLH
Mvan_0585|M.vanbaalenii_PYR-1 RPRTLSTVAG-DLELRIPKLRSGSFFPALLERRRRVDQCLFAVVMEAYLH
Mflv_3191|M.gilvum_PYR-GCK RPKTVSTTSG-DIEVQIPKLRAGSFFPSLLERRRRIDKALHAVIMEAYVH
TH_2000|M.thermoresistible__bu RPKTVSTTSG-DIEVQIPKLRAGSFFPSLLERRRRIDRALHAVIMEAYVH
Mb3461c|M.bovis_AF2122/97 RPKTVSTTAG-DIEVQIPKLRAGSFFPSLLERRRRIDKALHAVIMEAYVH
Rv3431c|M.tuberculosis_H37Rv RPKTVSTTAG-DIEVQIPKLRAGSFFPSLLERRRRIDKALHAVIMEAYVH
MSMEG_4154|M.smegmatis_MC2_155 RPKTVSTTAG-DVEVQIPKLRAGSFFPSLLERRRRIDRALHAVIMEAYVH
MUL_4531|M.ulcerans_Agy99 RSKTVLTDACGSIEIDVPRDRAGTFEPKIVEKRQRRLTDVDEVVLSLYAR
*.:*: * : .:*: :*: *:*:* * ::*:*:* : *::. * :
MAV_5116|M.avium_104 GTSTRKVDDLVKALGTDTGISKSEVSRICKDLDTEVAAFRDRPLGDQRFP
Mvan_0585|M.vanbaalenii_PYR-1 GTSTRKVDDLVKALGADSGISKSEVSRICKDLDTEVGAFRDRPLGEQRFP
Mflv_3191|M.gilvum_PYR-GCK GVSTRSVDDLVAAMGVESGVSKSEVSRICAGLDIEIEAFRTRSLAHTEFP
TH_2000|M.thermoresistible__bu GVSTRSVDDLVTAMGVGSGVSKSEVSRICAGLDEEIEAFRIRSLAHTQFP
Mb3461c|M.bovis_AF2122/97 GVSTRSVDDLVAAMGVQAGVSKSEVSRICAGLDTEIEAFRTRSLTHTEFP
Rv3431c|M.tuberculosis_H37Rv GVSTRSVDDLVAAMGVQAGVSKSEVSRICAGLDTEIEAFRTRSLTHTEFP
MSMEG_4154|M.smegmatis_MC2_155 GVSTRSVDDLVAALGVGSGVSKSEVSRICAGLDKEIDAFRTRSLNHTSFP
MUL_4531|M.ulcerans_Agy99 GLTTGEISAHFAHI-YDAAVSKDTVSRITDRVLEEITAWHTRPLER-VYA
* :* .:. . : :.:**. **** : *: *:: *.* :.
MAV_5116|M.avium_104 YVFLDATYCKARVNHRVVSQAVVIATGVAADGRREVLGFEVG--DSEDGA
Mvan_0585|M.vanbaalenii_PYR-1 YVFLDATYCKARVNHRVVSQAVVIATGVAADGRREVLGFEVG--DSEDGA
Mflv_3191|M.gilvum_PYR-GCK YIFCDATFCKVRVGAHVVSQALVVATGVSIDGTREVLGTAVG--DSESFE
TH_2000|M.thermoresistible__bu YVFCDATFCKVRIGAHVVSQALVVATGVSIDGTREVLGTAVG--DSESFE
Mb3461c|M.bovis_AF2122/97 YVFCDATFCKVRVGAHVVSQALVVATGVSIDGTREVLGTAVG--DSESYE
Rv3431c|M.tuberculosis_H37Rv YVFCDATFCKVRVGAHVVSQALVVATGVSIDGTREVLGTAVG--DSESYE
MSMEG_4154|M.smegmatis_MC2_155 YVFCDATFCKVRIGAHVVSQALVVATGVSIDGTREVLGTAVG--DSESFE
MUL_4531|M.ulcerans_Agy99 AVFIDALHVKIRD-GQVGPRPVYAAVGVDLAGHRDVLGMWAGEGDGESAK
:* ** . * * :* .:.: *.** * *:*** .* *.*.
MAV_5116|M.avium_104 FWTAFLRSLKSRGLAGVQLVISDAHAGLRSAIDAVLIGAAWQRCRVHFLR
Mvan_0585|M.vanbaalenii_PYR-1 FWTAFLRSLKSRGLAGVQLVISDAHAGLRAAIDAVLIGSAWQRCRVHFLR
Mflv_3191|M.gilvum_PYR-GCK FWREFLASLKARGLTGVHLVISDAHVGLKTAVAQQFTNSSWQRCRVHFMR
TH_2000|M.thermoresistible__bu FWREFLASLKARGLSGVHLVVSDAHAGLKAAVAQQFTNSSWQRCRVHFMR
Mb3461c|M.bovis_AF2122/97 FWREFLASLKARGLTGVHLVISDAHAGLKAAVAQQFSGASWQRCRVHFMR
Rv3431c|M.tuberculosis_H37Rv FWREFLASLKARGLTGVHLVISDAHAGLKAAVAQQFSGASWQRCRVHFMR
MSMEG_4154|M.smegmatis_MC2_155 FWREFLASLKARGLSGVHLVISDAHAGLKAAVAQQFTGSSWQRCRVHFMR
MUL_4531|M.ulcerans_Agy99 YWLAVLTELKNRGVADIFFLVCDGLKGLPDSVSAVFPDTVVQTCIIHLIR
:* .* .** **::.: :::.*. ** :: : .: * * :*::*
MAV_5116|M.avium_104 NVLAQVPKGSAEMVAAAIRTVFAQPDAEHVREQLDTIAGMLGRQFPKVET
Mvan_0585|M.vanbaalenii_PYR-1 NVLAQVPKGSAEMVAAAIRTIFAQPDAEHVREQLDTIAGMLGRQFPKVET
Mflv_3191|M.gilvum_PYR-GCK NLHTAVAAKHAPAVTAAVKTIFAHTDPVEVAAQWDRVADTLAPSFPKVAA
TH_2000|M.thermoresistible__bu NLHTAVAAKHAPAVTAAVKTIFAHTDPDEVAAQWDRVADTLAGSFPKVAA
Mb3461c|M.bovis_AF2122/97 NLYTAVAAKHAPAVTVAVKTIFAHTDPEEVGAQWDRVADPLCQP------
Rv3431c|M.tuberculosis_H37Rv NLYTAVAAKHAPAVTVAVKTIFAHTDPEEVGAQWDRVADPLCQP------
MSMEG_4154|M.smegmatis_MC2_155 NLHGVVAAKHAPAVTAAVKTIFAHTDPVDVAAQWDQVADTLAASFPKVAA
MUL_4531|M.ulcerans_Agy99 GTFRYAGRQHHTAIARALKPIYTAVNAAAAAEALDAFDTEWGHRYPAAIR
. . :: *::.::: :. . * .
MAV_5116|M.avium_104 MLREAAADITAFADFPVAHWKKIWSTNPLERLNKEIKRRTDVVGVFPNPA
Mvan_0585|M.vanbaalenii_PYR-1 MLREAAEDITAFADFPAAHWKKIWSTNPLERLNKEIKRRTDVVGVFPNPA
Mflv_3191|M.gilvum_PYR-GCK MMGEAKTDVLAFTAFPRAHWQKIWSNNPIERLNKEIKRRADVVEIFPNPA
TH_2000|M.thermoresistible__bu MMGEAKTDVLAFTAFPRAHWQKIWSNNPIERLNKEIKRRADVVEIFPNPA
Mb3461c|M.bovis_AF2122/97 --------------------------------------------------
Rv3431c|M.tuberculosis_H37Rv --------------------------------------------------
MSMEG_4154|M.smegmatis_MC2_155 MMDEAKADVLAFTAFPRTHWQKIWSNNPIVIC-------SAAVSVFY---
MUL_4531|M.ulcerans_Agy99 LWRNAWNEFIPFLDYDTEIRKVICSTNAIEWLNARYRRAIRARGHFPTEQ
MAV_5116|M.avium_104 ALLRLAGSVLVEAHDEWQVADKRYLSETSLALLDVSD-QSAETIAPTAAL
Mvan_0585|M.vanbaalenii_PYR-1 ALLRLAGSVLVEAHDEWQVADKRYLSETSLALLDTGE-QDTQTVAPTAAL
Mflv_3191|M.gilvum_PYR-GCK AFLRLATAVVIEAHDEWQVTRRYLSDISMDELRVVIEKKHAAAALAKQHQ
TH_2000|M.thermoresistible__bu AFLRLATAVVIEAHDEWQVTRRYLSDVSMDELRIVIEKKHAAAALAKQHQ
Mb3461c|M.bovis_AF2122/97 --------------------------------------------------
Rv3431c|M.tuberculosis_H37Rv --------------------------------------------------
MSMEG_4154|M.smegmatis_MC2_155 ---------VDHEGSEWSVLR-SGCGYLQPSMKQILEGRCACCEGGFTAL
MUL_4531|M.ulcerans_Agy99 SALKCLYLVTRSLDPTGTGQKRWTMRWKPALNAFAITFADRMPGSETT--
MAV_5116|M.avium_104 TA
Mvan_0585|M.vanbaalenii_PYR-1 TA
Mflv_3191|M.gilvum_PYR-GCK IT
TH_2000|M.thermoresistible__bu IA
Mb3461c|M.bovis_AF2122/97 --
Rv3431c|M.tuberculosis_H37Rv --
MSMEG_4154|M.smegmatis_MC2_155 VA
MUL_4531|M.ulcerans_Agy99 --