For questions or suggestions e-mail us at: ioerger@cs.tamu.edu

M. vanbaalenii PYR-1 Mvan_0585 (-)

annotation: transposase, mutator type
coordinates: 626263 - 627495
length: 410

MALDQSALLEVLDALRTADAGERITQACEIVYQALIDAELTAKIGAALHERTETRSNQRNGSRPRTLSTV
AGDLELRIPKLRSGSFFPALLERRRRVDQCLFAVVMEAYLHGTSTRKVDDLVKALGADSGISKSEVSRIC
KDLDTEVGAFRDRPLGEQRFPYVFLDATYCKARVNHRVVSQAVVIATGVAADGRREVLGFEVGDSEDGAF
WTAFLRSLKSRGLAGVQLVISDAHAGLRAAIDAVLIGSAWQRCRVHFLRNVLAQVPKGSAEMVAAAIRTI
FAQPDAEHVREQLDTIAGMLGRQFPKVETMLREAAEDITAFADFPAAHWKKIWSTNPLERLNKEIKRRTD
VVGVFPNPAALLRLAGSVLVEAHDEWQVADKRYLSETSLALLDTGEQDTQTVAPTAALTA
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. vanbaalenii PYR-1Mvan_0585--100% (410)transposase, mutator type
M. vanbaalenii PYR-1Mvan_0581-0.0100.00% (410) transposase, mutator type
M. vanbaalenii PYR-1Mvan_0550-0.0100.00% (410) transposase, mutator type

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb3664c-1e-13460.81% (393) putative transposase
M. gilvum PYR-GCKMflv_3191-1e-13160.15% (389) transposase, mutator type
M. tuberculosis H37RvRv3640c-1e-13460.81% (393) transposase
M. leprae Br4923-----
M. abscessus ATCC 19977-----
M. marinum M-----
M. avium 104MAV_5116-0.094.39% (410) transposase, Mutator family protein
M. smegmatis MC2 155MSMEG_4154-1e-11059.17% (338) transposase, Mutator family protein
M. thermoresistible (build 8)TH_2000-1e-12661.90% (357) PROBABLE TRANSPOSASE
M. ulcerans Agy99MUL_4029-1e-3831.75% (337) transposase for IS2606

CLUSTAL 2.0.9 multiple sequence alignment


Mvan_0585|M.vanbaalenii_PYR-1       ----------------------------MALDQSALLEVLDALRTA----
MAV_5116|M.avium_104                --------------MVKRPRITTERNIAMALDQSALLEVLDALRTA----
Mb3664c|M.bovis_AF2122/97           ----------------------------MALPQSALSELLDAFRTG----
Rv3640c|M.tuberculosis_H37Rv        ----------------------------MALPQSALSELLDAFRTG----
Mflv_3191|M.gilvum_PYR-GCK          ----------------------------MTQDHSALLAQLDALRSA----
TH_2000|M.thermoresistible__bu      --------------------------------------------------
MSMEG_4154|M.smegmatis_MC2_155      ----------------------------MTQDHSALLAQLDALKSA----
MUL_4029|M.ulcerans_Agy99           MMTKTVVVVQPSQNHEDEAGAVAAIDVPSSRDVDELEVARELVRQAREAG
                                                                                      

Mvan_0585|M.vanbaalenii_PYR-1       ----DAGERITQACEIVYQALIDAELTAKIGAALHERT-ETRSNQRNGSR
MAV_5116|M.avium_104                ----DAGERITQAAETIYQALIDAELTAFIGASPHERT-ETRSNQRNGSR
Mb3664c|M.bovis_AF2122/97           ----DGVDLIRDAVRLVLQELSELEATERIGAARYERS-DTRVTDRNGAR
Rv3640c|M.tuberculosis_H37Rv        ----DGVDLIRDAVRLVLQELSELEATERIGAARYERS-DTRVTDRNGAR
Mflv_3191|M.gilvum_PYR-GCK          ----DAGAVFAELIRAGLQQLIEAEATAAIGAGRYQRT-DGRMVHRNGHR
TH_2000|M.thermoresistible__bu      --------VFAELIRAGLQQLIEAEATAAIGAGRYERT-DGRTVHRNGHR
MSMEG_4154|M.smegmatis_MC2_155      ----DAGAVFAELIRAGLQALIEAEATEVIGAGRYQRT-DGRATHRNGHR
MUL_4029|M.ulcerans_Agy99           VGLTGPGGLLKAMTKTVIETALDEELSEHLGYDRHDRAGYGSGNSRNGTR
                                             :    .   :   : * :  :*   ::*:       *** *

Mvan_0585|M.vanbaalenii_PYR-1       PR-TLSTVAGDLELRIPKLRSGSFFPALLERRRRVDQCLFAVVMEAYLHG
MAV_5116|M.avium_104                PR-TLSTVAGDLELRIPKLRTGSFFPALLERRRRVDQCLFAVVMEAYLHG
Mb3664c|M.bovis_AF2122/97           SR-VLSTQAGDVELRIPKLRKGSFFPAILEPRRRIDQALYAVVMEAYVHG
Rv3640c|M.tuberculosis_H37Rv        SR-VLSTQAGDVELRIPKLRKGSFFPAILEPRRRIDQALYAVVMEAYVHG
Mflv_3191|M.gilvum_PYR-GCK          PK-TVSTTSGDIEVQIPKLRAGSFFPSLLERRRRIDKALHAVIMEAYVHG
TH_2000|M.thermoresistible__bu      PK-TVSTTSGDIEVQIPKLRAGSFFPSLLERRRRIDRALHAVIMEAYVHG
MSMEG_4154|M.smegmatis_MC2_155      PK-TVSTTAGDVEVQIPKLRAGSFFPSLLERRRRIDRALHAVIMEAYVHG
MUL_4029|M.ulcerans_Agy99           SKTVLTDACGSIEIDVPRDRAGTFEPKIVEKRQRRLTDVDEVVLSLYARG
                                    .: .::  .*.:*: :*: * *:* * ::* *:*    :  *::. * :*

Mvan_0585|M.vanbaalenii_PYR-1       TSTRKVDDLVKALGADSGISKSEVSRICKDLDTEVGAFRDRPLGEQRFPY
MAV_5116|M.avium_104                TSTRKVDDLVKALGTDTGISKSEVSRICKDLDTEVAAFRDRPLGDQRFPY
Mb3664c|M.bovis_AF2122/97           ISTRAVDDLVEAMGVETGISKSEVSRICAGLDEIVGAFRTRTLGHIEFPY
Rv3640c|M.tuberculosis_H37Rv        ISTRAVDDLVEAMGVETGISKSEVSRICAGLDEIVGAFRTRTLGHIEFPY
Mflv_3191|M.gilvum_PYR-GCK          VSTRSVDDLVAAMGVESGVSKSEVSRICAGLDIEIEAFRTRSLAHTEFPY
TH_2000|M.thermoresistible__bu      VSTRSVDDLVTAMGVGSGVSKSEVSRICAGLDEEIEAFRIRSLAHTQFPY
MSMEG_4154|M.smegmatis_MC2_155      VSTRSVDDLVAALGVGSGVSKSEVSRICAGLDKEIDAFRTRSLNHTSFPY
MUL_4029|M.ulcerans_Agy99           LTTGEISAHFAHI-YDAAVSKDTVSRITDRVLEEMTAWHTRPLER-VYAA
                                     :*  :.  .  :   :.:**. ****   :   : *:: *.*    :. 

Mvan_0585|M.vanbaalenii_PYR-1       VFLDATYCKAR-VNHRVVSQAVVIATGVAADGRREVLGFEVG--DSEDGA
MAV_5116|M.avium_104                VFLDATYCKAR-VNHRVVSQAVVIATGVAADGRREVLGFEVG--DSEDGA
Mb3664c|M.bovis_AF2122/97           VYLDATYLNVRNGTGQVVSMAVIVASGIAADGSREILGLDVG--DSEDET
Rv3640c|M.tuberculosis_H37Rv        VYLDATYLNVRNGTGQVVSMAVIVASGIAADGSREILGLDVG--DSEDET
Mflv_3191|M.gilvum_PYR-GCK          IFCDATFCKVR-VGAHVVSQALVVATGVSIDGTREVLGTAVG--DSESFE
TH_2000|M.thermoresistible__bu      VFCDATFCKVR-IGAHVVSQALVVATGVSIDGTREVLGTAVG--DSESFE
MSMEG_4154|M.smegmatis_MC2_155      VFCDATFCKVR-IGAHVVSQALVVATGVSIDGTREVLGTAVG--DSESFE
MUL_4029|M.ulcerans_Agy99           VFIDALHVKIR--DGQVGPRPVYAAVGVDLAGHRDVLGMWAGEGDGESAK
                                    :: ** . : *    :* . .:  * *:   * *::**  .*  *.*.  

Mvan_0585|M.vanbaalenii_PYR-1       FWTAFLRSLKSRGLAGVQLVISDAHAGLRAAIDAVLIGSAWQRCRVHFLR
MAV_5116|M.avium_104                FWTAFLRSLKSRGLAGVQLVISDAHAGLRSAIDAVLIGAAWQRCRVHFLR
Mb3664c|M.bovis_AF2122/97           FWRGFLTSLKGRGLGGVRLVISDQHAGLVKALKRCFQGAGHQRCRVHFAR
Rv3640c|M.tuberculosis_H37Rv        FWRGFLTSLKGRGLGGVRLVISDQHAGLVKALKRCFQGAGHQRCRVHFAR
Mflv_3191|M.gilvum_PYR-GCK          FWREFLASLKARGLTGVHLVISDAHVGLKTAVAQQFTNSSWQRCRVHFMR
TH_2000|M.thermoresistible__bu      FWREFLASLKARGLSGVHLVVSDAHAGLKAAVAQQFTNSSWQRCRVHFMR
MSMEG_4154|M.smegmatis_MC2_155      FWREFLASLKARGLSGVHLVISDAHAGLKAAVAQQFTGSSWQRCRVHFMR
MUL_4029|M.ulcerans_Agy99           YWLAVLTELKNRGVADIFFLVCDGLKGLPDSVSAVFPDTVVQTCIIHLIR
                                    :*  .* .** **: .: :::.*   **  ::   : .:  * * :*: *

Mvan_0585|M.vanbaalenii_PYR-1       NVLAQVPKGSAEMVAAAIRTIFAQPDAEHVREQLDTIAGMLGRQFPKVET
MAV_5116|M.avium_104                NVLAQVPKGSAEMVAAAIRTVFAQPDAEHVREQLDTIAGMLGRQFPKVET
Mb3664c|M.bovis_AF2122/97           NLLAHVPKDKADMVASMFRMIFSAPDAEAVHATWEEVRDRLAASFPKIGP
Rv3640c|M.tuberculosis_H37Rv        NLLAHVPKDKADMVASMFRMIFSAPDAEAVHATWEGVRDRLAASFPKIGP
Mflv_3191|M.gilvum_PYR-GCK          NLHTAVAAKHAPAVTAAVKTIFAHTDPVEVAAQWDRVADTLAPSFPKVAA
TH_2000|M.thermoresistible__bu      NLHTAVAAKHAPAVTAAVKTIFAHTDPDEVAAQWDRVADTLAGSFPKVAA
MSMEG_4154|M.smegmatis_MC2_155      NLHGVVAAKHAPAVTAAVKTIFAHTDPVDVAAQWDQVADTLAASFPKVAA
MUL_4029|M.ulcerans_Agy99           GTLRYPGRQHHTAIARALKPIYTAVNAAAAAEALDAFDTEWGHRYPAAIR
                                    .            ::  .: :::  :.  .    : .    .  :*    

Mvan_0585|M.vanbaalenii_PYR-1       MLREAAEDITAFADFPAAHWKKIWSTNPLERLNKEIKRRTDVVGVFPNPA
MAV_5116|M.avium_104                MLREAAADITAFADFPVAHWKKIWSTNPLERLNKEIKRRTDVVGVFPNPA
Mb3664c|M.bovis_AF2122/97           LMDDARAEVLAFTAFPKAHWQKIWSTNPLERINKEIKRRSRVVGIFPNPA
Rv3640c|M.tuberculosis_H37Rv        LMDDARAEVLAFTAFPKAHWQKIWSTNPLERINKEIKRRSRVVGIFPNPA
Mflv_3191|M.gilvum_PYR-GCK          MMGEAKTDVLAFTAFPRAHWQKIWSNNPIERLNKEIKRRADVVEIFPNPA
TH_2000|M.thermoresistible__bu      MMGEAKTDVLAFTAFPRAHWQKIWSNNPIERLNKEIKRRADVVEIFPNPA
MSMEG_4154|M.smegmatis_MC2_155      MMDEAKADVLAFTAFPRTHWQKIWSNNPIVIC-------SAAVSVFY---
MUL_4029|M.ulcerans_Agy99           LWRTAWNEFIPFLDYDTEIRKVICSTNAIESLNARYRRAIRARGHFPTEQ
                                    :   *  :. .*  :     : * *.*.:            .   *    

Mvan_0585|M.vanbaalenii_PYR-1       ALLRLAGSVLVEAHDEWQVADKRYLSETSLALLDTGEQDTQTVAPTAALT
MAV_5116|M.avium_104                ALLRLAGSVLVEAHDEWQVADKRYLSETSLALLDVSDQSAETIAPTAALT
Mb3664c|M.bovis_AF2122/97           AVIRLVGAVLADMHDEWQASERRYLSEASMALLYPDSDNAVVAAISGGQ-
Rv3640c|M.tuberculosis_H37Rv        AVIRLVGAVLADMHDEWQASERRYLSEASMALLYPDSDNAVVAAISGGQ-
Mflv_3191|M.gilvum_PYR-GCK          AFLRLATAVVIEAHDEWQVTRR-YLSDISMDELRVVIEKKHAAAALAKQH
TH_2000|M.thermoresistible__bu      AFLRLATAVVIEAHDEWQVTRR-YLSDVSMDELRIVIEKKHAAAALAKQH
MSMEG_4154|M.smegmatis_MC2_155      ---------VDHEGSEWSVLR--SGCGYLQPSMKQILEGRCACCEGGFTA
MUL_4029|M.ulcerans_Agy99           SALKCLYLVTRSLDPTGTGQKR--WTMRWKPALNAFAITFADRMPGSETT
                                                                    :             .   

Mvan_0585|M.vanbaalenii_PYR-1       A--
MAV_5116|M.avium_104                A--
Mb3664c|M.bovis_AF2122/97           ---
Rv3640c|M.tuberculosis_H37Rv        ---
Mflv_3191|M.gilvum_PYR-GCK          QIT
TH_2000|M.thermoresistible__bu      QIA
MSMEG_4154|M.smegmatis_MC2_155      LVA
MUL_4029|M.ulcerans_Agy99           ---