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M. ulcerans Agy99 MUL_4584 (-)

annotation: transposase for IS2606
coordinates: 5082945 - 5084279
length: 444

MMTKTVVAVQPSQNHEDEAGAVAAIDVPSSRDVDELEVARELVRQAREAGVGLTGPGGLLKAMTKTVIET
ALDEELSEHLGYDRHDRAGYGNGNSRNGTRSKTVLTDACGSIEIDVPRDRAGTFEPKIVEKRQRRLTDVD
EVVLSLYARGLTTGEISAHFAHIYDAAVSKDTVSRITDRVLEEMTAWHTRPLERVYAAVFIDALHVKIRD
GQVGPRPVYAAVGVDLAGHRDVLGMWAGEGDGESAKYWLAVLTELKNRGVADIFFLVCDGLKGLPDSVSA
VFPDTVVQTCIIHLIRGTFRYAGRQHHTAIARALKPIYTAVNAAAAAEALDAFDTEWGHRYPAAIRLWRN
AWNEFIPFLDYDTEIRKVICSTNAIESLNARYRRAIRARGHFPTEQSALKCLYLVTRSLDPTGTGQKRWT
MRWKPALNAFAITFADRMPGSETT
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. ulcerans Agy99MUL_4584--100% (444)transposase for IS2606
M. ulcerans Agy99MUL_4465-0.0100.00% (444) transposase for IS2606
M. ulcerans Agy99MUL_1495-0.0100.00% (444) transposase for IS2606

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb0944c-1e-17971.26% (435) putative transposase
M. gilvum PYR-GCKMflv_3191-3e-3328.24% (347) transposase, mutator type
M. tuberculosis H37RvRv0920c-1e-17971.03% (435) transposase
M. leprae Br4923-----
M. abscessus ATCC 19977-----
M. marinum M-----
M. avium 104MAV_3254-1e-11548.26% (431) transposase, Mutator family protein
M. smegmatis MC2 155MSMEG_4154-4e-3228.88% (322) transposase, Mutator family protein
M. thermoresistible (build 8)TH_3008-1e-9041.67% (420) PUTATIVE transposase, mutator type
M. vanbaalenii PYR-1Mvan_5974-1e-11347.91% (430) transposase, mutator type

CLUSTAL 2.0.9 multiple sequence alignment


Mb0944c|M.bovis_AF2122/97           MDAAQVIEPAHAGQDVDEA-AVAARELSG----AERALVGDLVRQARAEG
Rv0920c|M.tuberculosis_H37Rv        MDAAQVIEPAHAGQDVDEA-AVAARELSG----AERALVGDLVRQARAEG
MUL_4584|M.ulcerans_Agy99           MMTKTVVAVQPSQNHEDEAGAVAAIDVPSSRDVDELEVARELVRQAREAG
MAV_3254|M.avium_104                -----MSRSD---SSRDEAAKQLAQVLPP-------AALDALLADAEASG
Mvan_5974|M.vanbaalenii_PYR-1       -----MSRSE---SSADEAAAKLAQVLPA-------AAVDALLADAEATG
TH_3008|M.thermoresistible__bu      -----MTMTDEKGTSSTTGNELVAQLQAS-------GALDELFAKIDSGE
Mflv_3191|M.gilvum_PYR-GCK          ------------------------------------MTQDHSALLAQLDA
MSMEG_4154|M.smegmatis_MC2_155      ------------------------------------MTQDHSALLAQLDA
                                                                                      

Mb0944c|M.bovis_AF2122/97           VALTGPDGLLKALTKTVLEAALQEEMTEHLGYDRHAAAGRGSGNSRNGSR
Rv0920c|M.tuberculosis_H37Rv        VALTGPDGLLKALTKTVLEAALQEEMTEHLGYDRHAAAGRGSGNSRNGSR
MUL_4584|M.ulcerans_Agy99           VGLTGPGGLLKAMTKTVIETALDEELSEHLGYDRHDRAGYGNGNSRNGTR
MAV_3254|M.avium_104                TPIDGPDGLLAQITKSVLERALDVEIADHLGYEHGDPAGNGSGNSRNGHG
Mvan_5974|M.vanbaalenii_PYR-1       TPIDGPDGLLAQITKSVLERALDVEIADHLGYEHGDPAGNGSGNSRNGHG
TH_3008|M.thermoresistible__bu      VEITGSDGLLPALLKTTLERGLQAELTGHLGYEKGEPAPAKRPNARNGTT
Mflv_3191|M.gilvum_PYR-GCK          LRSADAGAVFAELIRAGLQQLIEAEATAAIGAGRYQRT-DGRMVHRNGHR
MSMEG_4154|M.smegmatis_MC2_155      LKSADAGAVFAELIRAGLQALIEAEATEVIGAGRYQRT-DGRATHRNGHR
                                        ....::  : :: ::  :: * :  :*  :   :       ***  

Mb0944c|M.bovis_AF2122/97           NKKVITDACGQVEIAVPRDRNGTFEPVIVGKRKRRVTDVDRVVLSLYAKG
Rv0920c|M.tuberculosis_H37Rv        NKKVITDACGQVEIAVPRDRNGTFEPVIVGKRKRRVTDVDRVVLSLYAKG
MUL_4584|M.ulcerans_Agy99           SKTVLTDACGSIEIDVPRDRAGTFEPKIVEKRQRRLTDVDEVVLSLYARG
MAV_3254|M.avium_104                RKTVLT-TAGPVDLEVPRDRNGTFDPVIVPKRKRRLGQVEDMILSLYARG
Mvan_5974|M.vanbaalenii_PYR-1       RKAVLT-TAGPVDLEVPRDRNGTFDPQIVPKRKRRLGQVEDMILSLYARG
TH_3008|M.thermoresistible__bu      SKTIES-EVGSFTIDVPRDRAGTFTPRLIRKGQRRLDGLDDMIISLYAGG
Mflv_3191|M.gilvum_PYR-GCK          PKTVST-TSGDIEVQIPKLRAGSFFPSLLERRRRIDKALHAVIMEAYVHG
MSMEG_4154|M.smegmatis_MC2_155      PKTVST-TAGDVEVQIPKLRAGSFFPSLLERRRRIDRALHAVIMEAYVHG
                                     * : :   * . : :*: * *:* * :: : :*    :. :::. *. *

Mb0944c|M.bovis_AF2122/97           LTTGEIAAHFADV-YGVSVSKDTISRITDRVIEEMQAWWSRPLEK-VYAA
Rv0920c|M.tuberculosis_H37Rv        LTTGEIAAHFADV-YGVSVSKDTISRITDRVIEEMQAWWSRPLEK-VYAA
MUL_4584|M.ulcerans_Agy99           LTTGEISAHFAHI-YDAAVSKDTVSRITDRVLEEMTAWHTRPLER-VYAA
MAV_3254|M.avium_104                MSTRDITEHLAEV-YGASVSAATVSRVTEVVADEIAAWQSRPVDP-VYPI
Mvan_5974|M.vanbaalenii_PYR-1       MSTRDITEHLGEV-YGATVSAATISRVTDVVADEIAAWQSRPVDP-VYPI
TH_3008|M.thermoresistible__bu      MTVREIEHHLATT-IGVELSAGTISAITDAVADAVLQWQNRPLEE-FYPV
Mflv_3191|M.gilvum_PYR-GCK          VSTRSVDDLVAAMGVESGVSKSEVSRICAGLDIEIEAFRTRSLAHTEFPY
MSMEG_4154|M.smegmatis_MC2_155      VSTRSVDDLVAALGVGSGVSKSEVSRICAGLDKEIDAFRTRSLNHTSFPY
                                    ::. .:   ..       :*   :* :   :   :  : .*.:    :. 

Mb0944c|M.bovis_AF2122/97           VFIDAIMVKIRDG-QVRNRPVYAAIGVDLDGHKDILGMWAGEGDGESAKF
Rv0920c|M.tuberculosis_H37Rv        VFIDAIMVKIRDG-QVRNRPVYAAIGVDLDGHKDILGMWAGEGDGESAKF
MUL_4584|M.ulcerans_Agy99           VFIDALHVKIRDG-QVGPRPVYAAVGVDLAGHRDVLGMWAGEGDGESAKY
MAV_3254|M.avium_104                LYIDAIRLKIRDGGVVSNKAAHVVIGVDVEGIKQVLGVWIQQTEG--AKF
Mvan_5974|M.vanbaalenii_PYR-1       LYIDAIRLKIRDGGVVANKAAHVVIGVDVDGIKQVLGVWIQQTEG--AKF
TH_3008|M.thermoresistible__bu      IYLDAIRIKVRQDHRVVGRSAYIAVGVDLEGIKHVLGIWVQDTEG--ASF
Mflv_3191|M.gilvum_PYR-GCK          IFCDATFCKVRVGAHVVSQALVVATGVSIDGTREVLGTAVGDSES--FEF
MSMEG_4154|M.smegmatis_MC2_155      VFCDATFCKVRIGAHVVSQALVVATGVSIDGTREVLGTAVGDSES--FEF
                                    :: **   *:* .  *  :.   . **.: * :.:**    : :.   .:

Mb0944c|M.bovis_AF2122/97           WLAVLTELRNRGVKDIFFLVCDGLKGLPDSVSAAFPLATVQTCIIHLIRN
Rv0920c|M.tuberculosis_H37Rv        WLAVLTDLRNRGVKDIFFLVCDGLKGLPDSVSAAFPLATVQTCIIHLIRN
MUL_4584|M.ulcerans_Agy99           WLAVLTELKNRGVADIFFLVCDGLKGLPDSVSAVFPDTVVQTCIIHLIRG
MAV_3254|M.avium_104                WHGVLTELRNRGCRDALFVCCDGLAGLPESIAAVWPQAVIQTCVVHLLRA
Mvan_5974|M.vanbaalenii_PYR-1       WHGVLTELRNRGCRDALFVCCDGLTGLPESITAVWPQAIIQTCVVHLLRA
TH_3008|M.thermoresistible__bu      WAHVCADLANRGVRDVLIVCCDGLAGLPEAIEATWPDSMVQTCVVHLIRA
Mflv_3191|M.gilvum_PYR-GCK          WREFLASLKARGLTGVHLVISDAHVGLKTAVAQQFTNSSWQRCRVHFMRN
MSMEG_4154|M.smegmatis_MC2_155      WREFLASLKARGLSGVHLVISDAHAGLKAAVAQQFTGSSWQRCRVHFMRN
                                    *  . :.*  **  .  :: .*.  **  ::   :. :  * * :*::* 

Mb0944c|M.bovis_AF2122/97           TFRYASRKYWDKISVDLKPIYTAASAAEARLRYEEFAE-KWGKPYPAITR
Rv0920c|M.tuberculosis_H37Rv        TFRYASRKYWDKISVDLKPIYTAASAAEARLRYEEFAE-KWGKPYPAITR
MUL_4584|M.ulcerans_Agy99           TFRYAGRQHHTAIARALKPIYTAVNAAAAAEALDAFDT-EWGHRYPAAIR
MAV_3254|M.avium_104                SMRYASYTDRKKMAAALRPIYTAATEQAAAVALEQFRT-EWKAKSPGAVA
Mvan_5974|M.vanbaalenii_PYR-1       SMRYASYTDRKKMAAALRPIYTAATEEAAKLALEEFRA-EWKTKSPGAVA
TH_3008|M.thermoresistible__bu      SMRFVSYGDRKKVAAELKKIYTAPNEETALAALAEFEASAWGAKYPQTVA
Mflv_3191|M.gilvum_PYR-GCK          LHTAVAAKHAPAVTAAVKTIFAHTDPVEVAAQWDRVAD-TLAPSFPKVAA
MSMEG_4154|M.smegmatis_MC2_155      LHGVVAAKHAPAVTAAVKTIFAHTDPVDVAAQWDQVAD-TLAASFPKVAA
                                        ..      ::  :: *::      .      .         *    

Mb0944c|M.bovis_AF2122/97           LWDSAWEEFIPFLDYDVEIRRVPCSTNAIESLNARYRRAVRARGHFPNEQ
Rv0920c|M.tuberculosis_H37Rv        LWDSAWEEFIPFLDYDVEIRRVPCSTNAIESLNARYRRAVRARGHFPNEQ
MUL_4584|M.ulcerans_Agy99           LWRNAWNEFIPFLDYDTEIRKVICSTNAIESLNARYRRAIRARGHFPTEQ
MAV_3254|M.avium_104                VWDRSWAEFVPFLAFPVEIRKIIYTTNAIESLNYQLRKVTKARGSFPSDA
Mvan_5974|M.vanbaalenii_PYR-1       VWDRAWAEFVPFLAFPVEIRKIIYTTNAIESLNYQLRKVTKARGSFPSDA
TH_3008|M.thermoresistible__bu      TWTAAWERFTPFLQFPPMLRRVIYTTNSIESLNFQLRKVTKNRGHFPSTE
Mflv_3191|M.gilvum_PYR-GCK          MMGEAKTDVLAFTAFPRAHWQKIWSNNPIERLNKEIKRRADVVEIFPNPA
MSMEG_4154|M.smegmatis_MC2_155      MMDEAKADVLAFTAFPRTHWQKIWSNNPIVIC-------SAAVSVFY---
                                        :   . .*  :     :   :.*.*                *    

Mb0944c|M.bovis_AF2122/97           SALKTLYLVTRSLD-----------------PKGTG---QTKWAVRWKPA
Rv0920c|M.tuberculosis_H37Rv        SALKTLYLVTRSLD-----------------PKGTG---QTKWAVRWKPA
MUL_4584|M.ulcerans_Agy99           SALKCLYLVTRSLD-----------------PTGTG---QKRWTMRWKPA
MAV_3254|M.avium_104                AAMKLLYLAIRNIN----------------QKRGSA---QGQGTYRWTEA
Mvan_5974|M.vanbaalenii_PYR-1       AALKLLYLAIRNIN----------------QKRGSN---PGSGTYRWTEA
TH_3008|M.thermoresistible__bu      SAVKLLWLAICNIEDRRARERAAEKGKPAGQRRASGRLVEGQVTTNWKQA
Mflv_3191|M.gilvum_PYR-GCK          AFLRLATAVVIEAHD---------------EWQVTRRYLSDISMDELRVV
MSMEG_4154|M.smegmatis_MC2_155      ---------VDHEGS---------------EWSVLR-SGCGYLQPSMKQI
                                                                                      

Mb0944c|M.bovis_AF2122/97           LNALAITFADRMPAAEER
Rv0920c|M.tuberculosis_H37Rv        LNALAITFADRMPAAEER
MUL_4584|M.ulcerans_Agy99           LNAFAITFADRMPGSETT
MAV_3254|M.avium_104                LNAFAIQFPDRLPL----
Mvan_5974|M.vanbaalenii_PYR-1       LNAFAIQFPDRLPL----
TH_3008|M.thermoresistible__bu      LAQLAAAYPDRINPYL--
Mflv_3191|M.gilvum_PYR-GCK          IEKKHAAAALAKQHQIT-
MSMEG_4154|M.smegmatis_MC2_155      LEGRCACCEGGFTALVA-
                                    :