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FAELIRAGLQALIEAEATEAIGAGRYERSDGRIVHRNGHRPKTVSTTAGDIEVQIPKLRAGSFFPSLLER RRRIDKALHAVIMEAYVHGVSTRSVDDLVAAMGVQAGVSKSEVSRICAGLDTEIEAFRTRSLTHTEFPYV FCDATFCKVRVGAHVVSQALVVATGVSIDGTREVLGTAVGDSESYEFWREFLASLKARGLTGVHLVISDA HAGLKAAVAQQFSGASWQRCRVHFMRNLYTAVAAKHAPAVTVAVKTIFAHTDPEEVGAQWDRVADPLCQP *
Operon Prediction Model: Genebank
Paralogs
species | id | gene | e-value | identity (len) | annotation |
M. tuberculosis H37Rv | Rv3431c | - | - | 100% (281) | POSSIBLE TRANSPOSASE (FRAGMENT) |
M. tuberculosis H37Rv | Rv3640c | - | 3e-89 | 60.87% (276) | transposase |
M. tuberculosis H37Rv | Rv3115 | - | 3e-56 | 45.09% (275) | transposase |
Closest Orthologs (e-value cutoff: 1e-4)
species | id | gene | e-value | identity (len) | annotation |
M. bovis AF2122 / 97 | Mb3461c | - | 1e-159 | 100.00% (281) | transposase |
M. gilvum PYR-GCK | Mflv_3191 | - | 1e-146 | 92.09% (278) | transposase, mutator type |
M. leprae Br4923 | - | - | - | - | - |
M. abscessus ATCC 19977 | - | - | - | - | - |
M. marinum M | - | - | - | - | - |
M. avium 104 | MAV_1238 | - | 9e-93 | 63.06% (268) | transposase, Mutator family protein |
M. smegmatis MC2 155 | MSMEG_4154 | - | 1e-143 | 89.93% (278) | transposase, Mutator family protein |
M. thermoresistible (build 8) | TH_2000 | - | 1e-144 | 91.01% (278) | PROBABLE TRANSPOSASE |
M. ulcerans Agy99 | MUL_4531 | - | 6e-31 | 33.86% (254) | transposase for IS2606 |
M. vanbaalenii PYR-1 | Mvan_0585 | - | 3e-90 | 61.57% (268) | transposase, mutator type |
CLUSTAL 2.0.9 multiple sequence alignment MAV_1238|M.avium_104 --------------MVKRPRITTERNIAMALDQSALLEVLDALRNADAA- Mvan_0585|M.vanbaalenii_PYR-1 ----------------------------MALDQSALLEVLDALRTADAG- Mflv_3191|M.gilvum_PYR-GCK ----------------------------MTQDHSALLAQLDALRSADAG- TH_2000|M.thermoresistible__bu -------------------------------------------------- Rv3431c|M.tuberculosis_H37Rv -------------------------------------------------- Mb3461c|M.bovis_AF2122/97 -------------------------------------------------- MSMEG_4154|M.smegmatis_MC2_155 ----------------------------MTQDHSALLAQLDALKSADAG- MUL_4531|M.ulcerans_Agy99 MMTKTVVAVQPSQNHEDEAGAVAAIDVPSSRDVDELEVARELVRQAREAG MAV_1238|M.avium_104 -------DRIKQAAETIYQALIDAELTAVIGAGPHERS-ASRTNQRNGSR Mvan_0585|M.vanbaalenii_PYR-1 -------ERITQACEIVYQALIDAELTAKIGAALHERT-ETRSNQRNGSR Mflv_3191|M.gilvum_PYR-GCK -------AVFAELIRAGLQQLIEAEATAAIGAGRYQRT-DGRMVHRNGHR TH_2000|M.thermoresistible__bu --------VFAELIRAGLQQLIEAEATAAIGAGRYERT-DGRTVHRNGHR Rv3431c|M.tuberculosis_H37Rv --------MFAELIRAGLQALIEAEATEAIGAGRYERS-DGRIVHRNGHR Mb3461c|M.bovis_AF2122/97 --------MFAELIRAGLQALIEAEATEAIGAGRYERS-DGRIVHRNGHR MSMEG_4154|M.smegmatis_MC2_155 -------AVFAELIRAGLQALIEAEATEVIGAGRYQRT-DGRATHRNGHR MUL_4531|M.ulcerans_Agy99 VGLTGPGGLLKAMTKTVIETALDEELSEHLGYDRHDRAGYGSGNSRNGTR : . : :: * : :* ::*: *** * MAV_1238|M.avium_104 PRTLSTIAG-DLELRIPKLRSGSFFPALLERRRRVDQCLFAVVMEAYLHG Mvan_0585|M.vanbaalenii_PYR-1 PRTLSTVAG-DLELRIPKLRSGSFFPALLERRRRVDQCLFAVVMEAYLHG Mflv_3191|M.gilvum_PYR-GCK PKTVSTTSG-DIEVQIPKLRAGSFFPSLLERRRRIDKALHAVIMEAYVHG TH_2000|M.thermoresistible__bu PKTVSTTSG-DIEVQIPKLRAGSFFPSLLERRRRIDRALHAVIMEAYVHG Rv3431c|M.tuberculosis_H37Rv PKTVSTTAG-DIEVQIPKLRAGSFFPSLLERRRRIDKALHAVIMEAYVHG Mb3461c|M.bovis_AF2122/97 PKTVSTTAG-DIEVQIPKLRAGSFFPSLLERRRRIDKALHAVIMEAYVHG MSMEG_4154|M.smegmatis_MC2_155 PKTVSTTAG-DVEVQIPKLRAGSFFPSLLERRRRIDRALHAVIMEAYVHG MUL_4531|M.ulcerans_Agy99 SKTVLTDACGSIEIDVPRDRAGTFEPKIVEKRQRRLTDVDEVVLSLYARG .:*: * : .:*: :*: *:*:* * ::*:*:* : *::. * :* MAV_1238|M.avium_104 TSTRKVDDLVKALGADAGISKSEVSRICADLDTEVGAFRDRPLSEQHFPY Mvan_0585|M.vanbaalenii_PYR-1 TSTRKVDDLVKALGADSGISKSEVSRICKDLDTEVGAFRDRPLGEQRFPY Mflv_3191|M.gilvum_PYR-GCK VSTRSVDDLVAAMGVESGVSKSEVSRICAGLDIEIEAFRTRSLAHTEFPY TH_2000|M.thermoresistible__bu VSTRSVDDLVTAMGVGSGVSKSEVSRICAGLDEEIEAFRIRSLAHTQFPY Rv3431c|M.tuberculosis_H37Rv VSTRSVDDLVAAMGVQAGVSKSEVSRICAGLDTEIEAFRTRSLTHTEFPY Mb3461c|M.bovis_AF2122/97 VSTRSVDDLVAAMGVQAGVSKSEVSRICAGLDTEIEAFRTRSLTHTEFPY MSMEG_4154|M.smegmatis_MC2_155 VSTRSVDDLVAALGVGSGVSKSEVSRICAGLDKEIDAFRTRSLNHTSFPY MUL_4531|M.ulcerans_Agy99 LTTGEISAHFAHI-YDAAVSKDTVSRITDRVLEEITAWHTRPLER-VYAA :* .:. . : :.:**. **** : *: *:: *.* . :. MAV_1238|M.avium_104 VFLDATYCKARVNHRVVSQAVVIATGVAVDGRREVLGFDVG--DSEDGAF Mvan_0585|M.vanbaalenii_PYR-1 VFLDATYCKARVNHRVVSQAVVIATGVAADGRREVLGFEVG--DSEDGAF Mflv_3191|M.gilvum_PYR-GCK IFCDATFCKVRVGAHVVSQALVVATGVSIDGTREVLGTAVG--DSESFEF TH_2000|M.thermoresistible__bu VFCDATFCKVRIGAHVVSQALVVATGVSIDGTREVLGTAVG--DSESFEF Rv3431c|M.tuberculosis_H37Rv VFCDATFCKVRVGAHVVSQALVVATGVSIDGTREVLGTAVG--DSESYEF Mb3461c|M.bovis_AF2122/97 VFCDATFCKVRVGAHVVSQALVVATGVSIDGTREVLGTAVG--DSESYEF MSMEG_4154|M.smegmatis_MC2_155 VFCDATFCKVRIGAHVVSQALVVATGVSIDGTREVLGTAVG--DSESFEF MUL_4531|M.ulcerans_Agy99 VFIDALHVKIRD-GQVGPRPVYAAVGVDLAGHRDVLGMWAGEGDGESAKY :* ** . * * :* .:.: *.** * *:*** .* *.*. : MAV_1238|M.avium_104 WTAFLRSLKTRGLSGVQLVISDAHTGLRSAIEAILIGASWQRCRVHFLRN Mvan_0585|M.vanbaalenii_PYR-1 WTAFLRSLKSRGLAGVQLVISDAHAGLRAAIDAVLIGSAWQRCRVHFLRN Mflv_3191|M.gilvum_PYR-GCK WREFLASLKARGLTGVHLVISDAHVGLKTAVAQQFTNSSWQRCRVHFMRN TH_2000|M.thermoresistible__bu WREFLASLKARGLSGVHLVVSDAHAGLKAAVAQQFTNSSWQRCRVHFMRN Rv3431c|M.tuberculosis_H37Rv WREFLASLKARGLTGVHLVISDAHAGLKAAVAQQFSGASWQRCRVHFMRN Mb3461c|M.bovis_AF2122/97 WREFLASLKARGLTGVHLVISDAHAGLKAAVAQQFSGASWQRCRVHFMRN MSMEG_4154|M.smegmatis_MC2_155 WREFLASLKARGLSGVHLVISDAHAGLKAAVAQQFTGSSWQRCRVHFMRN MUL_4531|M.ulcerans_Agy99 WLAVLTELKNRGVADIFFLVCDGLKGLPDSVSAVFPDTVVQTCIIHLIRG * .* .** **::.: :::.*. ** :: : .: * * :*::*. MAV_1238|M.avium_104 VLAQVPKGSAEMVAAAIRTIFAQPDAEHVREQLDTIAGMLGRQLPKVETM Mvan_0585|M.vanbaalenii_PYR-1 VLAQVPKGSAEMVAAAIRTIFAQPDAEHVREQLDTIAGMLGRQFPKVETM Mflv_3191|M.gilvum_PYR-GCK LHTAVAAKHAPAVTAAVKTIFAHTDPVEVAAQWDRVADTLAPSFPKVAAM TH_2000|M.thermoresistible__bu LHTAVAAKHAPAVTAAVKTIFAHTDPDEVAAQWDRVADTLAGSFPKVAAM Rv3431c|M.tuberculosis_H37Rv LYTAVAAKHAPAVTVAVKTIFAHTDPEEVGAQWDRVADPLCQP------- Mb3461c|M.bovis_AF2122/97 LYTAVAAKHAPAVTVAVKTIFAHTDPEEVGAQWDRVADPLCQP------- MSMEG_4154|M.smegmatis_MC2_155 LHGVVAAKHAPAVTAAVKTIFAHTDPVDVAAQWDQVADTLAASFPKVAAM MUL_4531|M.ulcerans_Agy99 TFRYAGRQHHTAIARALKPIYTAVNAAAAAEALDAFDTEWGHRYPAAIRL . :: *::.*:: :. . * . MAV_1238|M.avium_104 LREAADDITAFADFPVLHWKKIWSTNPLERLNKEIKRRTDVVGVFPNPAA Mvan_0585|M.vanbaalenii_PYR-1 LREAAEDITAFADFPAAHWKKIWSTNPLERLNKEIKRRTDVVGVFPNPAA Mflv_3191|M.gilvum_PYR-GCK MGEAKTDVLAFTAFPRAHWQKIWSNNPIERLNKEIKRRADVVEIFPNPAA TH_2000|M.thermoresistible__bu MGEAKTDVLAFTAFPRAHWQKIWSNNPIERLNKEIKRRADVVEIFPNPAA Rv3431c|M.tuberculosis_H37Rv -------------------------------------------------- Mb3461c|M.bovis_AF2122/97 -------------------------------------------------- MSMEG_4154|M.smegmatis_MC2_155 MDEAKADVLAFTAFPRTHWQKIWSNNPIVIC-------SAAVSVFY---- MUL_4531|M.ulcerans_Agy99 WRNAWNEFIPFLDYDTEIRKVICSTNAIEWLNARYRRAIRARGHFPTEQS MAV_1238|M.avium_104 LLRLAGSVLVEAHDEWQVAEKRYLS--ETTLALLHP-RSDSGAMIRTCG- Mvan_0585|M.vanbaalenii_PYR-1 LLRLAGSVLVEAHDEWQVADKRYLS--ETSLALLDTGEQDTQTVAPTAAL Mflv_3191|M.gilvum_PYR-GCK FLRLATAVVIEAHDEWQVTRRYLSDISMDELRVVIEKKHAAAALAKQHQI TH_2000|M.thermoresistible__bu FLRLATAVVIEAHDEWQVTRRYLSDVSMDELRIVIEKKHAAAALAKQHQI Rv3431c|M.tuberculosis_H37Rv -------------------------------------------------- Mb3461c|M.bovis_AF2122/97 -------------------------------------------------- MSMEG_4154|M.smegmatis_MC2_155 --------VDHEGSEWSVLR-SGCGYLQPSMKQILEGRCACCEGGFTALV MUL_4531|M.ulcerans_Agy99 ALK-CLYLVTRSLDPTGTGQKRWTMRWKPALNAFAITFADRMPGSETT-- MAV_1238|M.avium_104 -- Mvan_0585|M.vanbaalenii_PYR-1 TA Mflv_3191|M.gilvum_PYR-GCK T- TH_2000|M.thermoresistible__bu A- Rv3431c|M.tuberculosis_H37Rv -- Mb3461c|M.bovis_AF2122/97 -- MSMEG_4154|M.smegmatis_MC2_155 A- MUL_4531|M.ulcerans_Agy99 --