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M. tuberculosis H37Rv Rv3431c (-)

annotation: POSSIBLE TRANSPOSASE (FRAGMENT)
coordinates: 3849294 - 3850139
length: 281

FAELIRAGLQALIEAEATEAIGAGRYERSDGRIVHRNGHRPKTVSTTAGDIEVQIPKLRAGSFFPSLLER
RRRIDKALHAVIMEAYVHGVSTRSVDDLVAAMGVQAGVSKSEVSRICAGLDTEIEAFRTRSLTHTEFPYV
FCDATFCKVRVGAHVVSQALVVATGVSIDGTREVLGTAVGDSESYEFWREFLASLKARGLTGVHLVISDA
HAGLKAAVAQQFSGASWQRCRVHFMRNLYTAVAAKHAPAVTVAVKTIFAHTDPEEVGAQWDRVADPLCQP
*
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. tuberculosis H37RvRv3431c--100% (281)POSSIBLE TRANSPOSASE (FRAGMENT)
M. tuberculosis H37RvRv3640c-3e-8960.87% (276) transposase
M. tuberculosis H37RvRv3115-3e-5645.09% (275) transposase

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb3461c-1e-159100.00% (281) transposase
M. gilvum PYR-GCKMflv_3191-1e-14692.09% (278) transposase, mutator type
M. leprae Br4923-----
M. abscessus ATCC 19977-----
M. marinum M-----
M. avium 104MAV_1238-9e-9363.06% (268) transposase, Mutator family protein
M. smegmatis MC2 155MSMEG_4154-1e-14389.93% (278) transposase, Mutator family protein
M. thermoresistible (build 8)TH_2000-1e-14491.01% (278) PROBABLE TRANSPOSASE
M. ulcerans Agy99MUL_4531-6e-3133.86% (254) transposase for IS2606
M. vanbaalenii PYR-1Mvan_0585-3e-9061.57% (268) transposase, mutator type

CLUSTAL 2.0.9 multiple sequence alignment


MAV_1238|M.avium_104                --------------MVKRPRITTERNIAMALDQSALLEVLDALRNADAA-
Mvan_0585|M.vanbaalenii_PYR-1       ----------------------------MALDQSALLEVLDALRTADAG-
Mflv_3191|M.gilvum_PYR-GCK          ----------------------------MTQDHSALLAQLDALRSADAG-
TH_2000|M.thermoresistible__bu      --------------------------------------------------
Rv3431c|M.tuberculosis_H37Rv        --------------------------------------------------
Mb3461c|M.bovis_AF2122/97           --------------------------------------------------
MSMEG_4154|M.smegmatis_MC2_155      ----------------------------MTQDHSALLAQLDALKSADAG-
MUL_4531|M.ulcerans_Agy99           MMTKTVVAVQPSQNHEDEAGAVAAIDVPSSRDVDELEVARELVRQAREAG
                                                                                      

MAV_1238|M.avium_104                -------DRIKQAAETIYQALIDAELTAVIGAGPHERS-ASRTNQRNGSR
Mvan_0585|M.vanbaalenii_PYR-1       -------ERITQACEIVYQALIDAELTAKIGAALHERT-ETRSNQRNGSR
Mflv_3191|M.gilvum_PYR-GCK          -------AVFAELIRAGLQQLIEAEATAAIGAGRYQRT-DGRMVHRNGHR
TH_2000|M.thermoresistible__bu      --------VFAELIRAGLQQLIEAEATAAIGAGRYERT-DGRTVHRNGHR
Rv3431c|M.tuberculosis_H37Rv        --------MFAELIRAGLQALIEAEATEAIGAGRYERS-DGRIVHRNGHR
Mb3461c|M.bovis_AF2122/97           --------MFAELIRAGLQALIEAEATEAIGAGRYERS-DGRIVHRNGHR
MSMEG_4154|M.smegmatis_MC2_155      -------AVFAELIRAGLQALIEAEATEVIGAGRYQRT-DGRATHRNGHR
MUL_4531|M.ulcerans_Agy99           VGLTGPGGLLKAMTKTVIETALDEELSEHLGYDRHDRAGYGSGNSRNGTR
                                             :    .   :  :: * :  :*   ::*:       *** *

MAV_1238|M.avium_104                PRTLSTIAG-DLELRIPKLRSGSFFPALLERRRRVDQCLFAVVMEAYLHG
Mvan_0585|M.vanbaalenii_PYR-1       PRTLSTVAG-DLELRIPKLRSGSFFPALLERRRRVDQCLFAVVMEAYLHG
Mflv_3191|M.gilvum_PYR-GCK          PKTVSTTSG-DIEVQIPKLRAGSFFPSLLERRRRIDKALHAVIMEAYVHG
TH_2000|M.thermoresistible__bu      PKTVSTTSG-DIEVQIPKLRAGSFFPSLLERRRRIDRALHAVIMEAYVHG
Rv3431c|M.tuberculosis_H37Rv        PKTVSTTAG-DIEVQIPKLRAGSFFPSLLERRRRIDKALHAVIMEAYVHG
Mb3461c|M.bovis_AF2122/97           PKTVSTTAG-DIEVQIPKLRAGSFFPSLLERRRRIDKALHAVIMEAYVHG
MSMEG_4154|M.smegmatis_MC2_155      PKTVSTTAG-DVEVQIPKLRAGSFFPSLLERRRRIDRALHAVIMEAYVHG
MUL_4531|M.ulcerans_Agy99           SKTVLTDACGSIEIDVPRDRAGTFEPKIVEKRQRRLTDVDEVVLSLYARG
                                    .:*: * :  .:*: :*: *:*:* * ::*:*:*    :  *::. * :*

MAV_1238|M.avium_104                TSTRKVDDLVKALGADAGISKSEVSRICADLDTEVGAFRDRPLSEQHFPY
Mvan_0585|M.vanbaalenii_PYR-1       TSTRKVDDLVKALGADSGISKSEVSRICKDLDTEVGAFRDRPLGEQRFPY
Mflv_3191|M.gilvum_PYR-GCK          VSTRSVDDLVAAMGVESGVSKSEVSRICAGLDIEIEAFRTRSLAHTEFPY
TH_2000|M.thermoresistible__bu      VSTRSVDDLVTAMGVGSGVSKSEVSRICAGLDEEIEAFRIRSLAHTQFPY
Rv3431c|M.tuberculosis_H37Rv        VSTRSVDDLVAAMGVQAGVSKSEVSRICAGLDTEIEAFRTRSLTHTEFPY
Mb3461c|M.bovis_AF2122/97           VSTRSVDDLVAAMGVQAGVSKSEVSRICAGLDTEIEAFRTRSLTHTEFPY
MSMEG_4154|M.smegmatis_MC2_155      VSTRSVDDLVAALGVGSGVSKSEVSRICAGLDKEIDAFRTRSLNHTSFPY
MUL_4531|M.ulcerans_Agy99           LTTGEISAHFAHI-YDAAVSKDTVSRITDRVLEEITAWHTRPLER-VYAA
                                     :* .:.  .  :   :.:**. ****   :  *: *:: *.* .  :. 

MAV_1238|M.avium_104                VFLDATYCKARVNHRVVSQAVVIATGVAVDGRREVLGFDVG--DSEDGAF
Mvan_0585|M.vanbaalenii_PYR-1       VFLDATYCKARVNHRVVSQAVVIATGVAADGRREVLGFEVG--DSEDGAF
Mflv_3191|M.gilvum_PYR-GCK          IFCDATFCKVRVGAHVVSQALVVATGVSIDGTREVLGTAVG--DSESFEF
TH_2000|M.thermoresistible__bu      VFCDATFCKVRIGAHVVSQALVVATGVSIDGTREVLGTAVG--DSESFEF
Rv3431c|M.tuberculosis_H37Rv        VFCDATFCKVRVGAHVVSQALVVATGVSIDGTREVLGTAVG--DSESYEF
Mb3461c|M.bovis_AF2122/97           VFCDATFCKVRVGAHVVSQALVVATGVSIDGTREVLGTAVG--DSESYEF
MSMEG_4154|M.smegmatis_MC2_155      VFCDATFCKVRIGAHVVSQALVVATGVSIDGTREVLGTAVG--DSESFEF
MUL_4531|M.ulcerans_Agy99           VFIDALHVKIRD-GQVGPRPVYAAVGVDLAGHRDVLGMWAGEGDGESAKY
                                    :* ** . * *   :* .:.:  *.**   * *:***  .*  *.*.  :

MAV_1238|M.avium_104                WTAFLRSLKTRGLSGVQLVISDAHTGLRSAIEAILIGASWQRCRVHFLRN
Mvan_0585|M.vanbaalenii_PYR-1       WTAFLRSLKSRGLAGVQLVISDAHAGLRAAIDAVLIGSAWQRCRVHFLRN
Mflv_3191|M.gilvum_PYR-GCK          WREFLASLKARGLTGVHLVISDAHVGLKTAVAQQFTNSSWQRCRVHFMRN
TH_2000|M.thermoresistible__bu      WREFLASLKARGLSGVHLVVSDAHAGLKAAVAQQFTNSSWQRCRVHFMRN
Rv3431c|M.tuberculosis_H37Rv        WREFLASLKARGLTGVHLVISDAHAGLKAAVAQQFSGASWQRCRVHFMRN
Mb3461c|M.bovis_AF2122/97           WREFLASLKARGLTGVHLVISDAHAGLKAAVAQQFSGASWQRCRVHFMRN
MSMEG_4154|M.smegmatis_MC2_155      WREFLASLKARGLSGVHLVISDAHAGLKAAVAQQFTGSSWQRCRVHFMRN
MUL_4531|M.ulcerans_Agy99           WLAVLTELKNRGVADIFFLVCDGLKGLPDSVSAVFPDTVVQTCIIHLIRG
                                    *  .* .** **::.: :::.*.  **  ::   : .:  * * :*::*.

MAV_1238|M.avium_104                VLAQVPKGSAEMVAAAIRTIFAQPDAEHVREQLDTIAGMLGRQLPKVETM
Mvan_0585|M.vanbaalenii_PYR-1       VLAQVPKGSAEMVAAAIRTIFAQPDAEHVREQLDTIAGMLGRQFPKVETM
Mflv_3191|M.gilvum_PYR-GCK          LHTAVAAKHAPAVTAAVKTIFAHTDPVEVAAQWDRVADTLAPSFPKVAAM
TH_2000|M.thermoresistible__bu      LHTAVAAKHAPAVTAAVKTIFAHTDPDEVAAQWDRVADTLAGSFPKVAAM
Rv3431c|M.tuberculosis_H37Rv        LYTAVAAKHAPAVTVAVKTIFAHTDPEEVGAQWDRVADPLCQP-------
Mb3461c|M.bovis_AF2122/97           LYTAVAAKHAPAVTVAVKTIFAHTDPEEVGAQWDRVADPLCQP-------
MSMEG_4154|M.smegmatis_MC2_155      LHGVVAAKHAPAVTAAVKTIFAHTDPVDVAAQWDQVADTLAASFPKVAAM
MUL_4531|M.ulcerans_Agy99           TFRYAGRQHHTAIARALKPIYTAVNAAAAAEALDAFDTEWGHRYPAAIRL
                                        .       :: *::.*::  :.  .    * .              

MAV_1238|M.avium_104                LREAADDITAFADFPVLHWKKIWSTNPLERLNKEIKRRTDVVGVFPNPAA
Mvan_0585|M.vanbaalenii_PYR-1       LREAAEDITAFADFPAAHWKKIWSTNPLERLNKEIKRRTDVVGVFPNPAA
Mflv_3191|M.gilvum_PYR-GCK          MGEAKTDVLAFTAFPRAHWQKIWSNNPIERLNKEIKRRADVVEIFPNPAA
TH_2000|M.thermoresistible__bu      MGEAKTDVLAFTAFPRAHWQKIWSNNPIERLNKEIKRRADVVEIFPNPAA
Rv3431c|M.tuberculosis_H37Rv        --------------------------------------------------
Mb3461c|M.bovis_AF2122/97           --------------------------------------------------
MSMEG_4154|M.smegmatis_MC2_155      MDEAKADVLAFTAFPRTHWQKIWSNNPIVIC-------SAAVSVFY----
MUL_4531|M.ulcerans_Agy99           WRNAWNEFIPFLDYDTEIRKVICSTNAIEWLNARYRRAIRARGHFPTEQS
                                                                                      

MAV_1238|M.avium_104                LLRLAGSVLVEAHDEWQVAEKRYLS--ETTLALLHP-RSDSGAMIRTCG-
Mvan_0585|M.vanbaalenii_PYR-1       LLRLAGSVLVEAHDEWQVADKRYLS--ETSLALLDTGEQDTQTVAPTAAL
Mflv_3191|M.gilvum_PYR-GCK          FLRLATAVVIEAHDEWQVTRRYLSDISMDELRVVIEKKHAAAALAKQHQI
TH_2000|M.thermoresistible__bu      FLRLATAVVIEAHDEWQVTRRYLSDVSMDELRIVIEKKHAAAALAKQHQI
Rv3431c|M.tuberculosis_H37Rv        --------------------------------------------------
Mb3461c|M.bovis_AF2122/97           --------------------------------------------------
MSMEG_4154|M.smegmatis_MC2_155      --------VDHEGSEWSVLR-SGCGYLQPSMKQILEGRCACCEGGFTALV
MUL_4531|M.ulcerans_Agy99           ALK-CLYLVTRSLDPTGTGQKRWTMRWKPALNAFAITFADRMPGSETT--
                                                                                      

MAV_1238|M.avium_104                --
Mvan_0585|M.vanbaalenii_PYR-1       TA
Mflv_3191|M.gilvum_PYR-GCK          T-
TH_2000|M.thermoresistible__bu      A-
Rv3431c|M.tuberculosis_H37Rv        --
Mb3461c|M.bovis_AF2122/97           --
MSMEG_4154|M.smegmatis_MC2_155      A-
MUL_4531|M.ulcerans_Agy99           --