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M. gilvum PYR-GCK Mflv_1353 (-)

annotation: oxidoreductase FAD-binding subunit
coordinates: 1408358 - 1410904
length: 848

TETYSVALSFEDGVTRFINCRPDQTVADASYRQRINIPLDCRDGACGTCKALCETGSYDGGTYIDDALAP
DEAAAGYVLPCSMKPRSDLVLQIAATSDSAKTEAATYQGTLTLLERLSPTTVKIGIEIPNRGELAFLPGQ
YVNIAVPGTDQTRSYSFSNAPHEELLTFLVKLSPGGAMSDYLAHRAQVGDAVTFTGPNGSFFLREAQRPV
LLLAGGTGLAPILAMLRTMRAAGSTRTTHLIYGVSSDDDLTAVDEIEEIGAQLPSFTWDYCVSDPASSAP
NRGPDRAYVTSLIAPHHLHDGDLAIYLCGPPPMVEAVRTHLNTAGVEPTGFYYEKFGLATTRPTASSASL
PTPTADSPAIDAEALLPVPDARSVAGQVVLRPADLRPVQNRPTLVDDGAIRRLAGQTVFGPLAEPADDAT
VVSDDGYQIGEEHPEVRESDAIFEARSALELGALELTMGRLSSAQLAGYRLLAESTLPYVDGDRFVDAEQ
YTETNAAFHDYLFTLTRNDRLLQAYQALGVKGRMSEVLRHATWCHPRCAQDHVDIVAAFEAGDRDAARSL
IAAHAERSKQTMRRAMAETAEASAPVFVTPGRFAGKVVVVTGAAQGIGERTARRIHAEGGVLVLADRSEL
VKELADELAATSAAVAVTADLEHHEGAESVVQQALSAFGRIDVLINNVGGAINFKPFTEFTAAEVRAEID
RSLMTTLYSCHAALPSMVSRGRGVIVNVSSAATRGIHRIPYSAAKGGINAITASLAMEYADAGIRVVATA
PGGTAAPPRRISRGTPVPRDETEQAWFDAHITQTLDSSLLKRYGTLDEQAAAICFLASDEAAYITGTVLP
VAGGDLG*
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. gilvum PYR-GCKMflv_1353--100% (848)oxidoreductase FAD-binding subunit
M. gilvum PYR-GCKMflv_0661-1e-3339.61% (255) short-chain dehydrogenase/reductase SDR
M. gilvum PYR-GCKMflv_0566-1e-3339.61% (255) short-chain dehydrogenase/reductase SDR

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb1972-3e-5035.74% (333) oxygenase
M. tuberculosis H37RvRv1937-3e-5035.74% (333) oxygenase
M. leprae Br4923MLBr_01807fabG17e-1625.27% (281) 3-oxoacyl-
M. abscessus ATCC 19977MAB_1219-2e-2433.08% (260) short chain dehydrogenase
M. marinum MMMAR_2865-2e-5133.61% (357) oxygenase
M. avium 104MAV_0942-2e-2733.07% (251) 3-oxoacyl-(acyl-carrier-protein) reductase, putative
M. smegmatis MC2 155MSMEG_1906-0.069.35% (907) toluate 1,2-dioxygenase electron transfer component
M. thermoresistible (build 8)TH_4266-4e-2734.24% (257) PUTATIVE short-chain dehydrogenase/reductase SDR
M. ulcerans Agy99MUL_2889-1e-5133.61% (357) oxygenase
M. vanbaalenii PYR-1Mvan_4003-6e-5636.08% (352) oxidoreductase FAD-binding subunit

CLUSTAL 2.0.9 multiple sequence alignment


Mflv_1353|M.gilvum_PYR-GCK          -----------------MTETYSVALSFEDGVTRFINCRPDQTVADASYR
MSMEG_1906|M.smegmatis_MC2_155      MTVMIDRNSAQHPNTPEGDETFSVALSFEDGVTRFITCRADQTVADASYR
MAB_1219|M.abscessus_ATCC_1997      --------------------------------------------------
TH_4266|M.thermoresistible__bu      --------------------------------------------------
MLBr_01807|M.leprae_Br4923          --------------------------------------------------
MAV_0942|M.avium_104                --------------------------------------------------
Mb1972|M.bovis_AF2122/97            ------------------MAVRQVTVGYSDGTHKTMPVRCDQTVLDAAEE
Rv1937|M.tuberculosis_H37Rv         ------------------MAVRQVTVGYSDGTHKTMPVRCDQTVLDAAEE
MMAR_2865|M.marinum_M               ------------------MTVRHVTVGYSDGTHKTMPVRPDQSILEAAEE
MUL_2889|M.ulcerans_Agy99           ------------------MTVRHVTVGYSDGTHKTMPVRPDQSILEAAEE
Mvan_4003|M.vanbaalenii_PYR-1       ------------------MVVRQVTVGYSDGTHAAMPVKPEQTILEAAEE
                                                                                      

Mflv_1353|M.gilvum_PYR-GCK          QRINIPLDCRDGACGTCKALCETGSYDGGTYIDDALAPDEAAAGYVLPCS
MSMEG_1906|M.smegmatis_MC2_155      QRINIPLDCRDGACGTCKALCESGRYDAGTYIDDALAPDEAERGYVLPCS
MAB_1219|M.abscessus_ATCC_1997      --------------------------------------------------
TH_4266|M.thermoresistible__bu      --------------------------------------------------
MLBr_01807|M.leprae_Br4923          --------------------------------------------------
MAV_0942|M.avium_104                --------------------------------------------------
Mb1972|M.bovis_AF2122/97            HGVAIVNECQSGICGTCVATCTAGRYQMG--RTEGLSDVERAARKILTCQ
Rv1937|M.tuberculosis_H37Rv         HGVAIVNECQSGICGTCVATCTAGRYQMG--RTEGLSDVERAARKILTCQ
MMAR_2865|M.marinum_M               HGVAIVNECQSGICGTCVATCTAGRYDMG--RTEGLSDVERAARKILTCQ
MUL_2889|M.ulcerans_Agy99           HGVAIVNECQSGICGTCVATCTAGRYDMG--RTEGLSDVERAARKILTCQ
Mvan_4003|M.vanbaalenii_PYR-1       HGIAIVNECQSGICGTCVATCSSGDYEMG--RTEGLSDVERDARKVLTCQ
                                                                                      

Mflv_1353|M.gilvum_PYR-GCK          MKPRSDLVLQIAATSDSAKTEAATYQGTLTLLERLSPTTVKIGIEIPNRG
MSMEG_1906|M.smegmatis_MC2_155      MKPRSDLVLQIAGTSDIAKTQATRYTGTIVELTRLSATTVRFTVEIPDRA
MAB_1219|M.abscessus_ATCC_1997      --------------------------------------------------
TH_4266|M.thermoresistible__bu      --------------------------------------------------
MLBr_01807|M.leprae_Br4923          --------------------------------------------------
MAV_0942|M.avium_104                --------------------------------------------------
Mb1972|M.bovis_AF2122/97            TFVTSDCRIELQYPVDDNAALLVTGDGVVTAVELVSPSTAILRVDTSGMA
Rv1937|M.tuberculosis_H37Rv         TFVTSDCRIELQYPVDDNAALLVTGDGVVTAVELVSPSTAILRVDTSGMA
MMAR_2865|M.marinum_M               TFAESDCEIELQYPVDDNAALLVSGDGVVTGVDMVSPGTAVLRVDVSAMA
MUL_2889|M.ulcerans_Agy99           TLAESDCEIELQYPVDDNAALLVSGDGVVTGVDMVSPGTAVLRVDVSAMA
Mvan_4003|M.vanbaalenii_PYR-1       TFARTDCRIELQYPADDNAARLVTGHGTVTGIDRVSSSTALLRIDISEMG
                                                                                      

Mflv_1353|M.gilvum_PYR-GCK          ELAFLPG-QYVNIAVPGTDQTRSYSFSNAPHEEL-LTFLVKLSPGGAMSD
MSMEG_1906|M.smegmatis_MC2_155      DLAFLPG-QYVNITVPGTDITRSYSFSNPPDEAL-LTFLVKLVPGGAMSE
MAB_1219|M.abscessus_ATCC_1997      --------------------------------------------------
TH_4266|M.thermoresistible__bu      --------------------------------------------------
MLBr_01807|M.leprae_Br4923          --------------------------------------------------
MAV_0942|M.avium_104                --------------------------------------------------
Mb1972|M.bovis_AF2122/97            GALRYRAGQFAQLQVPGTNVWRNYSYAHPADGRGECEFIIRLLPDGVMSN
Rv1937|M.tuberculosis_H37Rv         GALRYRAGQFAQLQVPGTNVWRNYSYAHPADGRGECEFIIRLLPDGVMSN
MMAR_2865|M.marinum_M               GTIGYRAGQFAQLQVPGSDQWRNYSYAHPADGGGELEFIIRLLPDGAMSN
MUL_2889|M.ulcerans_Agy99           GTIGYRAGQFAQLQVPGSDQWRNYSYAHPADGGGDLEFIIRLLPDGAMSN
Mvan_4003|M.vanbaalenii_PYR-1       -AIDFMPGQFAQLQVPGTDVWRNYSYAHPADGRTELEFIIRLLPDGVMSN
                                                                                      

Mflv_1353|M.gilvum_PYR-GCK          YLAHRAQVGDAVTFTGPNGSFFLREAQRPVLLLAGGTGLAPILAMLRTMR
MSMEG_1906|M.smegmatis_MC2_155      YLSRRAVVGDAVSFTGPHGSFFLREAERPILLLAGGTGLAPVLSMLGKLR
MAB_1219|M.abscessus_ATCC_1997      --------------------------------------------------
TH_4266|M.thermoresistible__bu      --------------------------------------------------
MLBr_01807|M.leprae_Br4923          --------------------------------------------------
MAV_0942|M.avium_104                --------------------------------------------------
Mb1972|M.bovis_AF2122/97            YLRDRAQPGDHIALRCSKGSFYLRPIVRPVILVAGGTGLSAILAMAQSLD
Rv1937|M.tuberculosis_H37Rv         YLRDRAQPGDHIALRCSKGSFYLRPIVRPVILVAGGTGLSAILAMAQSLD
MMAR_2865|M.marinum_M               YLRDHAKQGDRIALRGSKGNFYLRPIVRPVVLVAGGTGLSAILAMAQSLP
MUL_2889|M.ulcerans_Agy99           YLRDHAKQGDRIALRGSKGNFYLRPIVRPVVLVAGGTGLSAILAMAQSLP
Mvan_4003|M.vanbaalenii_PYR-1       YLRDRAKPGDRIALRCSKGGFHLRPVVRPVVLVAGGTGLSAILAMAQSLD
                                                                                      

Mflv_1353|M.gilvum_PYR-GCK          AAGSTRTTHLIYGVSSDDDLTAVDEIEEIGAQLPSFTWDYCVSDPASSAP
MSMEG_1906|M.smegmatis_MC2_155      SDGSTRTAHLIYGVSSDADLVELDRIDEFASQLPAFTWSHCVSDPSSTSA
MAB_1219|M.abscessus_ATCC_1997      --------------------------------------------------
TH_4266|M.thermoresistible__bu      --------------------------------------------------
MLBr_01807|M.leprae_Br4923          --------------------------------------------------
MAV_0942|M.avium_104                --------------------------------------------------
Mb1972|M.bovis_AF2122/97            ADVAH-PVYLLYGVERTEDLCKLDELTELRRRVGRLEVHVVVARPDP---
Rv1937|M.tuberculosis_H37Rv         ADVAH-PVYLLYGVERTEDLCKLDELTELRRRVGRLEVHVVVARPDP---
MMAR_2865|M.marinum_M               ADPGQ-PVSLLYGVTSAEDLCKLDELEQLEHRVAGLQVHVIVARRDD---
MUL_2889|M.ulcerans_Agy99           ADPGQ-PVSLLYGVTSAEDLCKLDELEQLEHRVAGLQVHVTVARRDE---
Mvan_4003|M.vanbaalenii_PYR-1       AAIGQ-PIHLLYGVTGVEDLCKQHELAELERRIPGLQVHVVVARPDP---
                                                                                      

Mflv_1353|M.gilvum_PYR-GCK          NRGPDRAYVTSLIAPHHLHDGDLAIYLCGPPPMVEAVRTHLNTAGVEPTG
MSMEG_1906|M.smegmatis_MC2_155      N----KVRIPELISSEHLYGGDVAVYLCGPPPMVEAVRTHLTNSGVTPTG
MAB_1219|M.abscessus_ATCC_1997      --------------------------------------------------
TH_4266|M.thermoresistible__bu      --------------------------------------------------
MLBr_01807|M.leprae_Br4923          --------------------------------------------------
MAV_0942|M.avium_104                --------------------------------------------------
Mb1972|M.bovis_AF2122/97            DWDGRTGLVTDLLDERMLASGDADVYLCGPVAMVDAARTWLDHNGFHRVG
Rv1937|M.tuberculosis_H37Rv         DWDGRTGLVTDLLDERMLASGDADVYLCGPVAMVDAARTWLDHNGFHRVG
MMAR_2865|M.marinum_M               DWSGRTGLVTDLLDEAMLAGGDADVYLCGPAAMVEATRTWLSANGFHRAG
MUL_2889|M.ulcerans_Agy99           DWSGRTGLVTDLLDEAMLAGGDANVYLCGPAAMVEATRTWLSANGFHRAG
Mvan_4003|M.vanbaalenii_PYR-1       TWDGAVGLVTDLLDTGMLG-GDADVYLCGPGPMIEATRNWLDEHGIHGVG
                                                                                      

Mflv_1353|M.gilvum_PYR-GCK          FYYEKFGLATTRPTASSASLPTPTADSPAIDAEALLPVPDARSVAGQVVL
MSMEG_1906|M.smegmatis_MC2_155      FYFEKFGLTRAGAPDAPADR-SPAEESAAGPVENLLTAPDADAICGQQIP
MAB_1219|M.abscessus_ATCC_1997      --------------------------------------------------
TH_4266|M.thermoresistible__bu      --------------------------------------------------
MLBr_01807|M.leprae_Br4923          --------------------------------------------------
MAV_0942|M.avium_104                --------------------------------------------------
Mb1972|M.bovis_AF2122/97            LYYEKFVASGAARRRTPARLDYAGVDIAEVCRRGRGTAVVIGGSIAG---
Rv1937|M.tuberculosis_H37Rv         LYYEKFVASGAARRRTPARLDYAGVDIAEVCRRGRGTAVVIGGSIAG---
MMAR_2865|M.marinum_M               LYHEKFVASGAARRRTPARLDYSALDLAAVRRSGRGIAVVIGGSIAG---
MUL_2889|M.ulcerans_Agy99           LYHEKFVASGAARRRTPARLDYSALDLAAVRRSGRGIAVVIGGSIAG---
Mvan_4003|M.vanbaalenii_PYR-1       LYYEKFVASGSGPRRSRPHLDYATLDLADVRRCGHGTAVVVGGSIAG---
                                                                                      

Mflv_1353|M.gilvum_PYR-GCK          RPADLRPVQN---RP-------------------------TLVDDG----
MSMEG_1906|M.smegmatis_MC2_155      SSIDMAPAEQTASRPGHDHADNARRIAGQLIAPAAPGTATPLDDDGGALR
MAB_1219|M.abscessus_ATCC_1997      --------------------------------------------------
TH_4266|M.thermoresistible__bu      --------------------------------------------------
MLBr_01807|M.leprae_Br4923          --------------------------------------------------
MAV_0942|M.avium_104                --------------------------------------------------
Mb1972|M.bovis_AF2122/97            --------------------------------------------------
Rv1937|M.tuberculosis_H37Rv         --------------------------------------------------
MMAR_2865|M.marinum_M               --------------------------------------------------
MUL_2889|M.ulcerans_Agy99           --------------------------------------------------
Mvan_4003|M.vanbaalenii_PYR-1       --------------------------------------------------
                                                                                      

Mflv_1353|M.gilvum_PYR-GCK          --AIRRLAGQTVFGP--LAEPADDATV---------------VSDDGYQI
MSMEG_1906|M.smegmatis_MC2_155      ASGARSLAGQEVFAARAVAAPASVVEVPDDVPEPVHVQPPQPVAPDGYQI
MAB_1219|M.abscessus_ATCC_1997      --------------------------------------------------
TH_4266|M.thermoresistible__bu      --------------------------------------------------
MLBr_01807|M.leprae_Br4923          --------------------------------------------------
MAV_0942|M.avium_104                --------------------------------------------------
Mb1972|M.bovis_AF2122/97            -----------------------------------------IAAAKMLSE
Rv1937|M.tuberculosis_H37Rv         -----------------------------------------IAAAKMLSE
MMAR_2865|M.marinum_M               -----------------------------------------IAAAKVCSD
MUL_2889|M.ulcerans_Agy99           -----------------------------------------IAAAKVCSD
Mvan_4003|M.vanbaalenii_PYR-1       -----------------------------------------IAAAKVLSE
                                                                                      

Mflv_1353|M.gilvum_PYR-GCK          GEEHPEVRESDAIFEARSALELGALELTMGRLSSAQLAGYRLLAESTLPY
MSMEG_1906|M.smegmatis_MC2_155      GEEHPELHESDALFEARQALELGALELTIGRLSTAQLAGYRLLAESTLPY
MAB_1219|M.abscessus_ATCC_1997      --------------------------------------------------
TH_4266|M.thermoresistible__bu      --------------------------------------------------
MLBr_01807|M.leprae_Br4923          --------------------------------------------------
MAV_0942|M.avium_104                --------------------------------------------------
Mb1972|M.bovis_AF2122/97            TFDRVIVLEKDGPHRRREGRPGAAQGWHLHHLLTAGQIELERIFPGIVDD
Rv1937|M.tuberculosis_H37Rv         TFDRVIVLEKDGPHRRREGRPGAAQGWHLHHLLTAGQIELERIFPGIVDD
MMAR_2865|M.marinum_M               TFDRVIVLEKDDPHRRREGRPGAAQGWHLHHLLTAGQIELERFFPGIVDD
MUL_2889|M.ulcerans_Agy99           TFDRVIVLEKDDPHRRREGRPGAAQGWHLHHLLTAGQIELERFFPGIVDD
Mvan_4003|M.vanbaalenii_PYR-1       SFERVVVLEKDEPHRRREGRSGAAQGWHLHHLLTAGRIELERLFPGIIDD
                                                                                      

Mflv_1353|M.gilvum_PYR-GCK          VDGDRFVDAEQYTETNAAFHDYLFTLTRNDRLLQAYQALGVKGRMSEVLR
MSMEG_1906|M.smegmatis_MC2_155      VDGDRFVDAARYTETNAAFHDYLFTLTGNEHLLQAYQALDVKGRMSEVLR
MAB_1219|M.abscessus_ATCC_1997      --------------------------------------------------
TH_4266|M.thermoresistible__bu      --------------------------------------------------
MLBr_01807|M.leprae_Br4923          --------------------------------------------------
MAV_0942|M.avium_104                --------------------------------------------------
Mb1972|M.bovis_AF2122/97            MVREGAFKVDMAAQYRIRLGGTWKKPGTSDIEIVCAGRPLLEWCVRRRLD
Rv1937|M.tuberculosis_H37Rv         MVREGAFKVDMAAQYRIRLGGTWKKPGTSDIEIVCAGRPLLEWCVRRRLD
MMAR_2865|M.marinum_M               MVREGAFKVDMAAQYRIRLGGTWKKPGTSDIEIVCAGRPLLEWCVRRRLD
MUL_2889|M.ulcerans_Agy99           MVREGAFKVDMAAQYRIRLGGTWKKPGTSDIEIVCAGRPLLEWCVRRRLD
Mvan_4003|M.vanbaalenii_PYR-1       MVREGAFDVDMAAQYRIRLGGSWKKPGTGDIQIVCAGRPLLEWCVRRRLD
                                                                                      

Mflv_1353|M.gilvum_PYR-GCK          HATWCHPRCAQDHVDIVAAFEAGDRDAARSLIAAHAERSKQTMRRAMAET
MSMEG_1906|M.smegmatis_MC2_155      HATWCHPLCAQDHVRIVEAFEAHDRAAAKTLIMAHAECAKQTMRRALADQ
MAB_1219|M.abscessus_ATCC_1997      --------------------------------------------------
TH_4266|M.thermoresistible__bu      --------------------------------------------------
MLBr_01807|M.leprae_Br4923          --------------------------------------------------
MAV_0942|M.avium_104                --------------------------------------------------
Mb1972|M.bovis_AF2122/97            DEPRIDFRYESEVADLAFDRANNAIVGVAVDNGDADGGDGLQVVPAEFVV
Rv1937|M.tuberculosis_H37Rv         DEPRIDFRYESEVADLAFDRANNAIVGVAVDNGDADGGDGLQVVPAEFVV
MMAR_2865|M.marinum_M               DEPRIDFRYESEVTDLVFDRATNAVIGVAVP---GDGGE-PEVIPAEFVV
MUL_2889|M.ulcerans_Agy99           DEPRIDFRYESEVTDLVFDRATNAVIGVAVP---GDGGE-PEVIPAEFVL
Mvan_4003|M.vanbaalenii_PYR-1       DEPRISFLYESEVADLVYDRDNNTVVGVAVD----RGGPELEVIPAEFVV
                                                                                      

Mflv_1353|M.gilvum_PYR-GCK          AEAS--------APVFVTPGRFAGKVVVVTGAAQGIGERTARRIHAEGGV
MSMEG_1906|M.smegmatis_MC2_155      EQAEREKVRAARTPRFISPGRFRGKVVVVTGAAQGIGEHTARRINAEDGR
MAB_1219|M.abscessus_ATCC_1997      ------------------MGEFDNKVAIVTGAAQGIGEAYAHALAREGAA
TH_4266|M.thermoresistible__bu      ---------------VDDRFSMAGRVAVITGGGTGIGRASALVLAEYGAD
MLBr_01807|M.leprae_Br4923          ---MTDAAAKVSAAPGRGKPAFVSRSILVTGGNRGIGLAVARRLVADGHR
MAV_0942|M.avium_104                -----------------------MKTAVVTGGGSGIGLAVVERLRADGLN
Mb1972|M.bovis_AF2122/97            DASGKNTRVPEFLERLGVGAPEAEQDIINCFYSTMQHRVPPERRWQDKVM
Rv1937|M.tuberculosis_H37Rv         DASGKNTRVPEFLERLGVGAPEAEQDIINCFYSTMQHRVPPERRWQDKVM
MMAR_2865|M.marinum_M               DASGKNTHVPEFLERIGIGAPEVEQDMINCFYSTMQHQVPPERQWQDKVM
MUL_2889|M.ulcerans_Agy99           DASGKNTHVPEFLERIGIGAPEVEQDIINCFYSTMQHQVPPERQWQDKVM
Mvan_4003|M.vanbaalenii_PYR-1       DASGKNTHVPEFLDRVGVGAPEVEQDIINCFYSTMYHRVPPERQWDDKVM
                                                            :  :                      

Mflv_1353|M.gilvum_PYR-GCK          LVLADRSE-LVKELADELAAT-SAAVAVTADLEHHEGAESVVQQALSAFG
MSMEG_1906|M.smegmatis_MC2_155      VVMVDRAE-LVHDLADELSQTGPATLAVTADLEHPDGAETVVRQAIRKFG
MAB_1219|M.abscessus_ATCC_1997      VVVADINAEMGEGVAKQIVADGGRAIFAGVDVSDPDSAIAMADKAVSEFG
TH_4266|M.thermoresistible__bu      IVLAGRRPEPLKKTAAEIEALGRRALAVPTDVTAPDECRALVDATVGEFG
MLBr_01807|M.leprae_Br4923          VAVTHRAS-----------VVPDWFFGVECDVTDNDAIGAAFKAVEEHQG
MAV_0942|M.avium_104                VASIDLRP-----------SDAELAF--TADVTDRSQVDAALSAIRAQLG
Mb1972|M.bovis_AF2122/97            VICYAYRPFEDTYAAQYYTDSSRTILSTSLVAYNCYSPPRTAREFRAFAD
Rv1937|M.tuberculosis_H37Rv         VICYAYRPFEDTYAAQYYTDSSRTILSTSLVAYNCYSPPRTAREFRAFAD
MMAR_2865|M.marinum_M               VICYAYRPYEDTYAAQYYTDSSRTILSTSLVAYNCYSPPRTAREFREFAD
MUL_2889|M.ulcerans_Agy99           VICYAYRPYEDTYAAQYYTDSSRTILSTSLVAYNCYSPLRTVREFREFAD
Mvan_4003|M.vanbaalenii_PYR-1       MICYAYRPYEDTYAAQYYTDSSRTILSTTLVAYNCYSPPRTAREFREFAD
                                    :                        .                       .

Mflv_1353|M.gilvum_PYR-GCK          RIDVLINNVG--GAINFKPFTEFTAAEVRAEIDRSLMTTLYSCHAALPSM
MSMEG_1906|M.smegmatis_MC2_155      HIDVLINNVG--GAINFKPFTQFTADEIQAEITRSLMTTLYACRAALPAM
MAB_1219|M.abscessus_ATCC_1997      GIDYLVNNAAIYGGMKLDLLLSVPWDYYKKFMSVNQDGALVCTRAVYKHI
TH_4266|M.thermoresistible__bu      RLDVLVNNA---GGGATKPLMKWTDDEWHEVLNLNLSSAWYLSRAAAKPM
MLBr_01807|M.leprae_Br4923          PVEVLVANA---GITSDMLIMRMSEEQFQKVIDVNLTGVFRVAKLASRNM
MAV_0942|M.avium_104                PVTVLVNAA---GLDGFKKFNNITFEDWQRVIDVNLNGVFHTTQAVLPDM
Mb1972|M.bovis_AF2122/97            LMPSPVIGENIDGLEPASPIYNFRYPNMLRLRYEKKRNLPRALLAVGDAY
Rv1937|M.tuberculosis_H37Rv         LMPSPVIGENIDGLEPASPIYNFRYPNMLRLRYEKKRNLPRALLAVGDAY
MMAR_2865|M.marinum_M               LMPSPVIGENIDGLQPASPIYNFRYPNMLRLHYEKKRNLPRALLAVGDAY
MUL_2889|M.ulcerans_Agy99           LMPSPVIGENIDGLQPASPIYNFRYPNMLRLHYEKKRNLPRALLAVGDAY
Mvan_4003|M.vanbaalenii_PYR-1       LMPSPVVGENIDGLEPASPIYNFRYPNMLRLHYEKKRNLPRALLVVGDAY
                                     :   :      *      :              .          .    

Mflv_1353|M.gilvum_PYR-GCK          VSRG--RGVIVNVSSAATRGIHR--IPYSAAK--------GGINAITASL
MSMEG_1906|M.smegmatis_MC2_155      VEQG--HGVIVNVSSAATRGIHR--IPYSAAK--------GGINAITASL
MAB_1219|M.abscessus_ATCC_1997      AQRG--GGAIVNQSSTAAWLYS---GFYGLAK--------VGINGLTQQL
TH_4266|M.thermoresistible__bu      IDQG--RGAIVNISSGAGLLAMPQAPVYAAAK--------AGLNNLTGSM
MLBr_01807|M.leprae_Br4923          IKQR--FGRYIFMGSVVGLSGVPGQANYAASK--------SGLIGMARSL
MAV_0942|M.avium_104                IEAG--WGRIVNISSSSTHSGAPYMSHYVAAK--------SAVNGLTKSL
Mb1972|M.bovis_AF2122/97            TSADPVSGLGMSLALKEVREMQALLAKYGAGHRDLPRRYYRAIAKMADTA
Rv1937|M.tuberculosis_H37Rv         TSADPVSGLGMSLALKEVREMQALLAKYGAGHRDLPRRYYRAIAKMADTA
MMAR_2865|M.marinum_M               TSADPVSGLGMSLALKEVREMQLLLSKYGPTHRELPRKYYRTIAKMADTA
MUL_2889|M.ulcerans_Agy99           TSADPVSGLGMSLALKEVREMQLLLSKYGPTHRELPRKYYRTIAKMADTA
Mvan_4003|M.vanbaalenii_PYR-1       TSADPVSGLGMTLALKEVREMALLLAKYGPGHPELPRRYFRRIAKMADTA
                                     .     *  :  .             *   :          :  ::   

Mflv_1353|M.gilvum_PYR-GCK          AMEYADAGIRVVATAPGGTAAPPRRISRGTPVPRDETEQAWF-DAHITQT
MSMEG_1906|M.smegmatis_MC2_155      AMEYADAGIRVVATAPGGTDAPPRRISRGTPAPADDTERAWF-QAHIDQT
MAB_1219|M.abscessus_ATCC_1997      SRELGGQKIRINAIAPG---------PTDTEATRGTVPEQ----FRSELV
TH_4266|M.thermoresistible__bu      AAAWTRKGVRVNCIACG---------AIRTPGLEADAKRQG---FDIDMI
MLBr_01807|M.leprae_Br4923          ARELGSRSITANVVAPG---------FIDTEMTRAMDSK-----YQEAAL
MAV_0942|M.avium_104                ALEYGPKGITVNAVPPG---------FIDTPMLRAAEKNGFL-GDIEETI
Mb1972|M.bovis_AF2122/97            WFVIREQNLRFDWMKDVDKKRPFYFGVLTWYMDRVLELVHDDLDAYREFL
Rv1937|M.tuberculosis_H37Rv         WFVIREQNLRFDWMKDVDKKRPFYFGVLTWYMDRVLELVHDDLDAYREFL
MMAR_2865|M.marinum_M               WFVIREQNLRFNWLKDVDKKRPFYFGALTWYMDRLLELVHDDLDAYREFL
MUL_2889|M.ulcerans_Agy99           WFVIREQNLRLNWLKDVDKKRPFYFGALTWYMDRLLELVHDDLDAYREFL
Mvan_4003|M.vanbaalenii_PYR-1       WFVIREQNLRFDWLKDVDKKRPFYFRALTWYMDRVMELVHDDPDTYGEFL
                                            :                                         

Mflv_1353|M.gilvum_PYR-GCK          LDSSLLKRYGTLDEQAAAICFLASDEAAYITGTVLPVAGGDLG-------
MSMEG_1906|M.smegmatis_MC2_155      LASSLMHRYGTLDEQAAAICFLASDEASYITGSVLPVAGGDLG-------
MAB_1219|M.abscessus_ATCC_1997      KNIPLS-RMGTVDDMVGMCLFLLSDKASWITGQVFNVDGGQIIRS-----
TH_4266|M.thermoresistible__bu      GQTNGSGRIAEPDEIGYGVLFFASDASSYCSGQTLYMHGGPGPAGV----
MLBr_01807|M.leprae_Br4923          QAIPLG-RIGAVEEIAGAVSFLASEDAGYISGAVIPVDGGLGMGH-----
MAV_0942|M.avium_104                ARTPVR-RMGTPQDIAAACAFLVSEEAGYITGQILGVNGGRNT-------
Mb1972|M.bovis_AF2122/97            AVVHLVKPPSALMRPRIASRVLGKWARTRLSGQKTLIARNYENHPIPAEP
Rv1937|M.tuberculosis_H37Rv         AVVHLVKPPSALMRPRIASRVLGKWARTRLSGQKTLIARNYENHPIPAEP
MMAR_2865|M.marinum_M               AVVHLVKPPLALMKPGIASRVIGKWARTRLSGQKTLIARNYENHTAPAEP
MUL_2889|M.ulcerans_Agy99           AVVHLVKPPLALMKPGIASRVIGKWARTRLSGQKTLIARNYENHTAPAEP
Mvan_4003|M.vanbaalenii_PYR-1       AVVHLVRPPAALMTPKVAGKVLGKWARTRLSGQKTLIARNYENRTVP--P
                                                        .: .      :*    :  .          

Mflv_1353|M.gilvum_PYR-GCK          --------------------
MSMEG_1906|M.smegmatis_MC2_155      --------------------
MAB_1219|M.abscessus_ATCC_1997      --------------------
TH_4266|M.thermoresistible__bu      --------------------
MLBr_01807|M.leprae_Br4923          --------------------
MAV_0942|M.avium_104                --------------------
Mb1972|M.bovis_AF2122/97            ADQLVNA-------------
Rv1937|M.tuberculosis_H37Rv         ADQLVNA-------------
MMAR_2865|M.marinum_M               ADQLVTVGDLR---------
MUL_2889|M.ulcerans_Agy99           ADQLVTVGDLR---------
Mvan_4003|M.vanbaalenii_PYR-1       VDHLVRTEELSVGLVGTRTH