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AAMETSTAPLDEPAGLTDADGFTPLRVKDVIRETTDAVSLILDVPELIEDRFRYTAGQFVTVKTTIRGEE HRRCYSMSSSPHVGPDLRITVKRDRDGVVSNWINDTAAAGDRLLTAPPDGRFVLTTADRDVVTFAGGSGV TPVFSLVNTTLATTGRRVRMFYANRDADSVIFRDALTRLTDSHSDRLHVHHHLDTRDGVVSARHITEFLG ASTVSTAEADFYICGPAPFMDTVERVLLDAGVPAQRVHLERFTVTPADPAVEAESAATEEVTIVLGRTTV TQPYRAGTTLLQTARLAGLKAPSSCEVGTCGTCIGQVVEGSARLLNNDALDDDEIAEGWVVTCQALPTSH TVKVVYE*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. smegmatis MC2 155 | MSMEG_0295 | - | - | 100% (358) | oxidoreductase, FAD-binding |
| M. smegmatis MC2 155 | MSMEG_6039 | - | 6e-57 | 37.71% (358) | oxidoreductase, electron transfer component |
| M. smegmatis MC2 155 | MSMEG_2893 | - | 2e-54 | 36.44% (343) | oxidoreductase, NAD/FAD-binding |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3602 | hmp | 2e-59 | 37.88% (359) | hemoglobine-like protein |
| M. gilvum PYR-GCK | Mflv_2468 | - | 1e-112 | 59.94% (342) | ferredoxin |
| M. tuberculosis H37Rv | Rv3571 | hmp | 2e-59 | 37.88% (359) | hemoglobine-like protein |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_3918c | - | 1e-62 | 38.53% (340) | putative oxidoreductase |
| M. marinum M | MMAR_5066 | hmp | 3e-59 | 38.16% (359) | flavodoxin reductase Hmp |
| M. avium 104 | MAV_3963 | - | 8e-79 | 56.30% (254) | 2Fe-2S iron-sulfur cluster binding domain-containing protein |
| M. thermoresistible (build 8) | TH_2828 | - | 1e-120 | 63.50% (337) | PUTATIVE ferredoxin |
| M. ulcerans Agy99 | MUL_4142 | hmp | 2e-59 | 38.16% (359) | flavodoxin reductase Hmp |
| M. vanbaalenii PYR-1 | Mvan_4186 | - | 1e-117 | 61.38% (347) | ferredoxin |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_2468|M.gilvum_PYR-GCK -MVEELS------------VDGFAPLRIKRVVRETSDAVSLVLDVPEDCS
Mvan_4186|M.vanbaalenii_PYR-1 -MAEELTDP----------AEGFAPLRIRRVVRETADAVSLVLDVPECCS
TH_2828|M.thermoresistible__bu -MSEETV--------------GFAPLRIKRVVRETRDAVSLVLDVPPECS
MSMEG_0295|M.smegmatis_MC2_155 MAAMETSTAPLDEPAGLTDADGFTPLRVKDVIRETTDAVSLILDVPELIE
MAV_3963|M.avium_104 -MAEQRT--------------------------ATHDGP-----------
Mb3602|M.bovis_AF2122/97 -MTEAIG-DEP------LG-DHVLELQIAEVVDETDEARSLVFAVPDGSD
Rv3571|M.tuberculosis_H37Rv -MTEAIG-DEP------LG-DHVLELQIAEVVDETDEARSLVFAVPDGSD
MMAR_5066|M.marinum_M -MTDAIP-DEP------LG-SHVLELQIAEVVAETDDARSLVFAVPDGSD
MUL_4142|M.ulcerans_Agy99 -MTDAIP-DEP------LG-SHVLELQIAEVVAETDDARSLVFAVPDGSD
MAB_3918c|M.abscessus_ATCC_199 -MTDSVLPDTPR----VTGNPHVHSLEVVEIIRETGDAVSLVFEVPDALV
* :.
Mflv_2468|M.gilvum_PYR-GCK H------RFRYKAGQFLTVRVS-VDGRDLRRCYSMSSAPVEE-ELRITVK
Mvan_4186|M.vanbaalenii_PYR-1 H------RFQYKAGQFLTLRVS-VGGRDLRRCYSMSSAPVED-ELRITVK
TH_2828|M.thermoresistible__bu D------RFRYRAGQFLTLQVE-IAGGRHRRCYSMSSSPHNGSDLQITVK
MSMEG_0295|M.smegmatis_MC2_155 D------RFRYTAGQFVTVKTT-IRGEEHRRCYSMSSSPHVGPDLRITVK
MAV_3963|M.avium_104 ----------------ATVTAP-ESGG-----------------------
Mb3602|M.bovis_AF2122/97 DPEIPPRRLRYAPGQFLTLRVPSERTGSVARCYSLCSSPYTDDALAVTVK
Rv3571|M.tuberculosis_H37Rv DPEIPPRRLRYAPGQFLTLRVPSERTGSVARCYSLCSSPYTDDALAVTVK
MMAR_5066|M.marinum_M DPRIPPERLRYAPGQFLTLRVPSERTGSVARCYSLCSSPFTDDALTVTVK
MUL_4142|M.ulcerans_Agy99 DPRIPPERLRYAPGQFLTLRVPSERTGSVARCYSLCSSPFTDDALTVTVK
MAB_3918c|M.abscessus_ATCC_199 D------AFRYRPGQFLTLKIPSEQTGSVARCYSLSSSPHLDDDLVVTVK
*:
Mflv_2468|M.gilvum_PYR-GCK RDPGGLVSNWINDTAAEGDELHASPPEGRFTLAEGVSSPRPLIAFAGGSG
Mvan_4186|M.vanbaalenii_PYR-1 RDPGGVVSNWINDTAAAGDELHAAPPEGRFTLTESDSSPRELVAFAGGSG
TH_2828|M.thermoresistible__bu RDPGGLVSNYLNDTAAAGVEIYASPPDGRFVLG---AADRDVVAFAGGSG
MSMEG_0295|M.smegmatis_MC2_155 RDRDGVVSNWINDTAAAGDRLLTAPPDGRFVLT---TADRDVVTFAGGSG
MAV_3963|M.avium_104 -----------TDTAGPGGRLYALPPRGRFVLT---DTDRQLVAFAGGSG
Mb3602|M.bovis_AF2122/97 RTADGYASNWLCDHAQVGMRIHVLAPSGNFVPT---TLDADFLLLAAGSG
Rv3571|M.tuberculosis_H37Rv RTADGYASNWLCDHAQVGMRIHVLAPSGNFVPT---TLDADFLLLAAGSG
MMAR_5066|M.marinum_M RTADGYASNWLCDNAHQGMRIHVLAPSGNFVPK---TLDDDFLLLAAGSG
MUL_4142|M.ulcerans_Agy99 RTADGYASNWLCDNAHQGMRIHVLAPSGNFVPK---TLDDDFLLLAAGSG
MAB_3918c|M.abscessus_ATCC_199 RTDGGYASNWLCDNVGVGDHITVLTPSGVFVPR---SLDSDFLLIAAGSG
* . * .: . .* * *. .: :*.***
Mflv_2468|M.gilvum_PYR-GCK ITPIMSLVRAALADTARPVRLFYANRARGSVIFSEPLARLTEQHADRLTV
Mvan_4186|M.vanbaalenii_PYR-1 ITPIMSLVRAALAGSDRTVKLFYANRGRDSVIFSEPLARLAEQHADRLTV
TH_2828|M.thermoresistible__bu ITPVYSLIEYALATTDRRVKLFYANRSRDSVIFGAALEELVAAHPRRLSI
MSMEG_0295|M.smegmatis_MC2_155 VTPVFSLVNTTLATTGRRVRMFYANRDADSVIFRDALTRLTDSHSDRLHV
MAV_3963|M.avium_104 ITPVFSLLRTALTAGTRRARLFYANRSRDAVIFDEDLADLQRRHAERFTL
Mb3602|M.bovis_AF2122/97 ITPIMSICKSALAEGGGQVTLLYANRDDRSVIFGDALRELAAKYPDRLTV
Rv3571|M.tuberculosis_H37Rv ITPIMSICKSALAEGGGQVTLLYANRDDRSVIFGDALRELAAKYPDRLTV
MMAR_5066|M.marinum_M ITPIMSICKSTLAEGSGQVTLLYANRDERSVIFADALRELSAKYPDRLTV
MUL_4142|M.ulcerans_Agy99 ITPIMSICKSALAEGGGQVTLLYANRDERSVIFADALRELSAKYPDRLTV
MAB_3918c|M.abscessus_ATCC_199 ITPMLSIAKSVLLGGAGTVYLFYANRDAQSVIFGAEIDDIMVEFPDRLRV
:**: *: . .* . ::**** :*** : : .. *: :
Mflv_2468|M.gilvum_PYR-GCK AHHFDEDAGVVTATAVASF--AESAG--DADYYICGPAPFMDTVEASLLD
Mvan_4186|M.vanbaalenii_PYR-1 EHHYDEDAGVVTASAVESF--AARVG--DADFYVCGPTPFMDTVETALLG
TH_2828|M.thermoresistible__bu VHHFDDESGVVRPAAVEAF--AEAVGGDGADFYICGPGPFMDTVEQTLVN
MSMEG_0295|M.smegmatis_MC2_155 HHHLDTRDGVVSARHITEFLGASTVSTAEADFYICGPAPFMDTVERVLLD
MAV_3963|M.avium_104 HHHLDDQRGFATQEDISAF--IATAG--DADFYVCGPNEFMDTVCTALRD
Mb3602|M.bovis_AF2122/97 LHWLESLQGLPSASALAKL----VAPYTDRPVFICGPGPFMQAARDALAA
Rv3571|M.tuberculosis_H37Rv LHWLESLQGLPSASALAKL----VAPYTDRPVFICGPGPFMQAARDALAA
MMAR_5066|M.marinum_M VHWLESLQGLPSATALAQL----AAPFTGRTAFICGPGPFMEAARVALQT
MUL_4142|M.ulcerans_Agy99 VHWLESLQGLPSATALAQL----AAPFTGRTAFICGPGPFMEAARVALQT
MAB_3918c|M.abscessus_ATCC_199 VHWLEAERGLPTRDAMSEL----FAAYTRYSTYLCGPAPFMEEARAALSA
* : *. : : . ::*** **: . *
Mflv_2468|M.gilvum_PYR-GCK SGVPKQRLNLERFTIAE----VPPGVTDNTDDACEEIVIELDRQKVTAAY
Mvan_4186|M.vanbaalenii_PYR-1 AGVPKQRLHLERFTVAA----APDTVTDGDAQACEEVVIELQRQKVTAAY
TH_2828|M.thermoresistible__bu RGVPRDRLHLERFELTP----ASGAAIQ-AGEQTEEVIIELDRKTTTAPY
MSMEG_0295|M.smegmatis_MC2_155 AGVPAQRVHLERFTVTP----ADP-AVEAESAATEEVTIVLGRTTVTQPY
MAV_3963|M.avium_104 AGIAAERVHVEHFDVTD----VGAAAPAEGQVQPGEVTIVLDGATTTAPY
Mb3602|M.bovis_AF2122/97 LKVPAQQVHIEVFKSLESDPFAAVKVDDSGDEAPATAVVELDGQTHTVSW
Rv3571|M.tuberculosis_H37Rv LKVPAQQVHIEVFKSLESDPFAAVKVDDSGDEAPATAVVELDGQTHTVSW
MMAR_5066|M.marinum_M LDVPAGQVHIEVFKSLESDPFAAVTVEDSAAEPPATAVVELDGQTHTVSW
MUL_4142|M.ulcerans_Agy99 LDVPAGQVHIEVFKSLESDPFAAVTVEDSAAEPPATAVVELDGQTHTVSW
MAB_3918c|M.abscessus_ATCC_199 VGMPANHIHLEHYQSLSGDPFADIVIPQGGADA-AQATVELDGTRVTVEW
:. ::::* : . : * * :
Mflv_2468|M.gilvum_PYR-GCK RQGETLLQTARQKGLKAPASCETGSCGTCMARIVEGSARMRINDALDEDE
Mvan_4186|M.vanbaalenii_PYR-1 RQGDTLLQTARLQGLKAPSSCETGSCGTCMARIVEGSARMLNNDALEPDE
TH_2828|M.thermoresistible__bu RSGNTLLQTARIAGLRAPSSCETGSCGTCMARLVAGSARMLNNDALDGDE
MSMEG_0295|M.smegmatis_MC2_155 RAGTTLLQTARLAGLKAPSSCEVGTCGTCIGQVVEGSARLLNNDALDDDE
MAV_3963|M.avium_104 QAGNTLLQTARMAGLRAPSSCEIGSCGTCMARLTQGSARMINNDALDPEE
Mb3602|M.bovis_AF2122/97 PRTAKLLDVLLAAGLDAPFSCREGHCGACACTLRAGKVNMGVNDVLEQQD
Rv3571|M.tuberculosis_H37Rv PRTAKLLDVLLAAGLDAPFSCREGHCGACACTLRAGKVNMGVNDVLEQQD
MMAR_5066|M.marinum_M PRSAKLLDVLLAAGLDAPFSCREGHCGACAATLRSGKVNMEVNDVLEQQD
MUL_4142|M.ulcerans_Agy99 PRSAKLLDVLLAAGLDAPFSCREGHCGACAATLRSGKVNMEVNDVLEQQD
MAB_3918c|M.abscessus_ATCC_199 PRNTPLLDVLLARGIDAPYSCREGACSACACTVRRGEVRMLRNDTLVDAD
**:. *: ** **. * *.:* : *...: **.* :
Mflv_2468|M.gilvum_PYR-GCK VEEGWVLTCQSLPTSRKVHVVYE-
Mvan_4186|M.vanbaalenii_PYR-1 VEEGWVVTCQALPTSSKVHMIYE-
TH_2828|M.thermoresistible__bu VAEGWVLTCQALPTSRSVHVRYE-
MSMEG_0295|M.smegmatis_MC2_155 IAEGWVVTCQALPTSHTVKVVYE-
MAV_3963|M.avium_104 VDDGWVLTCQALPTSPTVRVVYE-
Mb3602|M.bovis_AF2122/97 LDEGLILACQSRPESDSVEVTYDE
Rv3571|M.tuberculosis_H37Rv LDEGLILACQSRPESDSVEVTYDE
MMAR_5066|M.marinum_M LDDGLILACQSHPESDSVEVTYDE
MUL_4142|M.ulcerans_Agy99 LDDGLILACQSHPESDSVEVTYDE
MAB_3918c|M.abscessus_ATCC_199 LAMGLTLACQAVPVTDSVDIAFDQ
: * ::**: * : .* : ::