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MNSEQFDAVIVGAGFAGIGTAIQLKRSGIENFVILDREDDLGGTWYVNHYPGLAVDVPTTTYSYFFEPNP NWSRLFSTGDEIKQYADHVADKYDVRRHIRFGVTVEGARWDEDATLWRVSLADGTTLSSRYLLTATGFLS QPHMPDIPGITEFEGRVIHTTAWDDSYDPSGEKIAVIGTGATAVQLIPELAKKAADLTVYQRTPIWVVPK VDFRFSERAKRLFARVPQTQRVLRWLTDSIYEVMVSVAVRHYGMFRGRFNISAADLAKIHRFVTIRDKDL RRRLTPDYDFGCKRPTFSNSYYRTFTKPHVHLQDTGIARVESDGIVAGDGTKTVIDTLVLATGFDLWEAN FPAIEVIGRDGRNLGKWWRETRFQAYQGVSIPYFPNYLSLASPYAFIGLNFFNTMEYQMRLMDRLFGELR RRGATTFEVTEEANAEFLDRMTDLLGESLFTIGNCASARSYYFNPAGEPTLLRPTSTETAIREATEFPVT DYSFG
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. gilvum PYR-GCK | Mflv_0184 | - | - | 100% (495) | FAD-dependent pyridine nucleotide-disulphide oxidoreductase |
| M. gilvum PYR-GCK | Mflv_3372 | - | 0.0 | 65.38% (494) | FAD-dependent pyridine nucleotide-disulphide oxidoreductase |
| M. gilvum PYR-GCK | Mflv_3377 | - | 0.0 | 63.49% (493) | FAD dependent oxidoreductase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1428c | - | 1e-105 | 39.34% (488) | monoxygenase |
| M. tuberculosis H37Rv | Rv1393c | - | 1e-105 | 39.34% (488) | monoxygenase |
| M. leprae Br4923 | MLBr_00065 | - | 1e-30 | 30.25% (367) | putative monooxygenase |
| M. abscessus ATCC 19977 | MAB_2477c | - | 0.0 | 61.89% (488) | monooxygenase |
| M. marinum M | MMAR_3138 | - | 1e-107 | 40.16% (498) | monooxygenase |
| M. avium 104 | MAV_2172 | - | 0.0 | 71.02% (490) | FAD dependent oxidoreductase, putative |
| M. smegmatis MC2 155 | MSMEG_0816 | - | 0.0 | 76.43% (488) | flavin-binding monooxygenase |
| M. thermoresistible (build 8) | TH_4080 | - | 5e-83 | 35.24% (471) | PUTATIVE conserved hypothetical protein |
| M. ulcerans Agy99 | MUL_1793 | - | 1e-104 | 40.29% (489) | monoxygenase |
| M. vanbaalenii PYR-1 | Mvan_0721 | - | 0.0 | 85.16% (492) | FAD-dependent pyridine nucleotide-disulphide oxidoreductase |
CLUSTAL 2.0.9 multiple sequence alignment
Mb1428c|M.bovis_AF2122/97 ------------------MMPDYHALIVGAGFSGIGAAIKLD-RAGFSDY
Rv1393c|M.tuberculosis_H37Rv ------------------MMPDYHALIVGAGFSGIGAAIKLD-RAGFSDY
MUL_1793|M.ulcerans_Agy99 -------------------------MIVGAGFSGIGAAISLD-KAGFGDY
MMAR_3138|M.marinum_M --------------MGSESGQHYEIVIVGAGFSGIGTAISLL-KAGFADF
Mflv_0184|M.gilvum_PYR-GCK -----------------MNSEQFDAVIVGAGFAGIGTAIQLK-RSGIENF
Mvan_0721|M.vanbaalenii_PYR-1 -----------------MISEHFDAVIVGAGFAGIGAAIQFK-RMGIENF
MSMEG_0816|M.smegmatis_MC2_155 -----------------MRPVVHDAVIVGAGFAGLGAAIQLK-KMSFDDF
MAV_2172|M.avium_104 -----------------MVTDRFDAIIVGAGFGGIGAAIQLK-RLGFDNI
MAB_2477c|M.abscessus_ATCC_199 ------------------MTTQFDAVIVGAGFGGMGAAIQLK-ELGLTNL
TH_4080|M.thermoresistible__bu MTVTEPSADITPANTPTQPPVRTRALIVGTGFSGLGMAIALQ-RRGID-F
MLBr_00065|M.leprae_Br4923 -------------MVVMAETEYLDVVIVGAGISGVSAAWHLQDRCPNKSY
:***:*:.*:. * : .
Mb1428c|M.bovis_AF2122/97 LVVEAGDGVGGTWHWNTYPGIAVDIPSFSYQFSFEQSRHWSRTYAPGHEL
Rv1393c|M.tuberculosis_H37Rv LVVEAGDGVGGTWHWNTYPGIAVDIPSFSYQFSFEQSRHWSRTYAPGHEL
MUL_1793|M.ulcerans_Agy99 LVIEAGDAVGGTWFWNTYPGIAVDIPSFSYQFSFEQSPDWSRSYAPGREL
MMAR_3138|M.marinum_M LIVDDADGVGGTWHWNTYPGIAVDIPSYSYQFSYEMRTSWSRTYAHGDEL
Mflv_0184|M.gilvum_PYR-GCK VILDREDDLGGTWYVNHYPGLAVDVPTTTYSYFFEPNPNWSRLFSTGDEI
Mvan_0721|M.vanbaalenii_PYR-1 VILEREDDLGGTWYVNHYPGLAVDVPTTTYSYFFEPNPNWSRLFSTGAEI
MSMEG_0816|M.smegmatis_MC2_155 VILEREDDLGGTWYVNHYPGLAVDVPTTTYSYFFEPNPSWSRLFSTGREI
MAV_2172|M.avium_104 VILDREDDLGGTWHVNHYPGIAVDIPSTTYSYWFEPNPGWSRLFAPGGEV
MAB_2477c|M.abscessus_ATCC_199 AILDREDDLGGTWHVNHYPGLAVDIPSATYSYSFEPNPYWSRLFAPGSEL
TH_4080|M.thermoresistible__bu LMLEKADDIGGTWRDNTYPGCACDIPSHLYSFSFEPKADWRHLFSYQDEI
MLBr_00065|M.leprae_Br4923 VILEKRAGMGGTWDLFRYPGIRSDSDMYTLGFRFRPWTKCQAIAD-GKPI
::: :**** *** * : :. :
Mb1428c|M.bovis_AF2122/97 KAYAEHCVDKYGIRSRIRLNTKVLAAEFDDEHSLWRVQTDPGGE---ITA
Rv1393c|M.tuberculosis_H37Rv KAYAEHCVDKYGIRSRIRLNTKVLAAEFDDEHSLWRVQTDPGGE---ITA
MUL_1793|M.ulcerans_Agy99 RAYAEHCADKYGIRPRIRFNTKVLGAELDDERSLWRLQTDPGGD---LIT
MMAR_3138|M.marinum_M KAYAERCVEKYGLQNYIRFNTTVDEACFDEGAALWRLSCSSGQN---LTA
Mflv_0184|M.gilvum_PYR-GCK KQYADHVADKYDVRRHIRFGVTVEGARWDEDATLWRVSLADGTT---LSS
Mvan_0721|M.vanbaalenii_PYR-1 KQYADDVADKYDVRRHIRFGVTVGGARWDDDAQLWRVNLADGET---VDA
MSMEG_0816|M.smegmatis_MC2_155 KRYADDVADKYDVRRHIRFGTTVTGARWDEDDNVWQVSLTDGEQ---LQA
MAV_2172|M.avium_104 KQYAADVADKYDVRRHMRFNTTVEGAQWDEDAEVWRVALAGGES---LTT
MAB_2477c|M.abscessus_ATCC_199 KQYASHVADKHDLRKYMRFNTPVSGARWDEEHQHWVVATESGDT---VTG
TH_4080|M.thermoresistible__bu QEYLQGVTAKYGLRRYIHFDSLVDRAHWDDTEHRWHVFTADGRE---YIA
MLBr_00065|M.leprae_Br4923 LEYIKSTAVMHGIDKYIRLNHKVTGADWSSIENRWTVQVENNGTPRMISC
* . :.: :::. * * .. * : .
Mb1428c|M.bovis_AF2122/97 RFLISACGILTVPK--LPDIDGVDSFEGVTMHTARWDHTQDLTGKRVGII
Rv1393c|M.tuberculosis_H37Rv RFLISACGILTVPK--LPDIDGVDSFEGVTMHTARWDHTQDLTGKRVGII
MUL_1793|M.ulcerans_Agy99 RFIINASGVLTVPK--LPDIAGVDSFAGVTMHTARWDHSQELTGKRVGII
MMAR_3138|M.marinum_M RFVINCSGVLSRPK--WPDIPGVRDFAGVTLHTARWDHTKDLTGKRVAVI
Mflv_0184|M.gilvum_PYR-GCK RYLLTATGFLSQPH--MPDIPGITEFEGRVIHTTAWDDSYDPSGEKIAVI
Mvan_0721|M.vanbaalenii_PYR-1 RYLVTATGFLSQPH--MPDIPGIAEFDGRVIHTTAWDDSYDPTGEKIGII
MSMEG_0816|M.smegmatis_MC2_155 RFLITATGFLSQPH--TPDIPGITEFDGKVIHTTDWDDGCSLYGRRAAVV
MAV_2172|M.avium_104 RFLITATGFLSQPH--TPDIPGIGSFGGKVVHTTAWDHDYRYQGRRIAVI
MAB_2477c|M.abscessus_ATCC_199 KYLLTATGYLSQPK--MPDIEGIESFAGKVIHTTKWDNSYRAAGHRIGLI
TH_4080|M.thermoresistible__bu QFLISCAGALHIPS--IPDFPGRDQFAGPAFHSAQWDHSVDLTGKRVAVI
MLBr_00065|M.leprae_Br4923 SFLFLCSGYYNYEQGYAPTFLGSEDFTGPIIHPQHWPEDLDYAAKNIVVI
::. . * * : * .* * .*. * . ... ::
Mb1428c|M.bovis_AF2122/97 GTGASAVQVIPEMAPI-VSHLTVFQRTPIWCFPKFDVPLPTAVRWAMR-I
Rv1393c|M.tuberculosis_H37Rv GTGASAVQVIPEMAPI-VSHLTVFQRTPIWCFPKFDVPLPTAVRWAMR-I
MUL_1793|M.ulcerans_Agy99 GTGASAVQVIPEIAPI-VKHLTVFQRTPIWCFPKFDFPLPAALRWAMR-I
MMAR_3138|M.marinum_M GTGASAVQLIPEVAKI-ASSLTVFQRTPIYCLPKPDFSIPSWAATVMRLV
Mflv_0184|M.gilvum_PYR-GCK GTGATAVQLIPELAKK-AADLTVYQRTPIWVVPKVDFRFSERAKRLFARV
Mvan_0721|M.vanbaalenii_PYR-1 GTGATAVQLIPELAEK-AADLTVYQRTPIWVVPKIDFRFSERAKQLFARI
MSMEG_0816|M.smegmatis_MC2_155 GTGATAVQLIPELAER-VAELTVYQRTPIWVVPKVDVRFPPAVRALFARV
MAV_2172|M.avium_104 GTGASAVQVVPELAKE-AEELTVYQRTATHVLPKVDFEFDPAVRRLFARV
MAB_2477c|M.abscessus_ATCC_199 GTGATAVQLIPELAKD-AQHLTVYQRTPIWVVPKADAKVPGVVKKLFAKV
TH_4080|M.thermoresistible__bu GTGASAIQIVPEIIDR-VAQLQLYQRTPAWVVPRTNDELPAWLRRALENI
MLBr_00065|M.leprae_Br4923 GSGATAVTLVPALANSGAKHVTMLQRSPTYIVSQPAKDKIAARLNRWLPD
*:**:*: ::* : . : : **:. ..:
Mb1428c|M.bovis_AF2122/97 PGGKAVHRLLSQAFVEATFPIAAHYFAVFP--LAKHMESAGRRYLRQQVH
Rv1393c|M.tuberculosis_H37Rv PGGKAVHRLLSQAFVEATFPIAAHYFAVFP--LAKHMESAGRRYLRQQVH
MUL_1793|M.ulcerans_Agy99 PGGKALQRLLSQAYVEATFPISAHYFTVFP--LARWSAVLGRRYLRQRVD
MMAR_3138|M.marinum_M PGAQLMTRTASQAFVEFTFPIAAHFHSLIP--VSDLMEEAAKRYMRRAVD
Mflv_0184|M.gilvum_PYR-GCK PQTQRVLRWLTDSIYEVMVSVAVRHYGMFRGRFNISAADLAKIHRFVTIR
Mvan_0721|M.vanbaalenii_PYR-1 PLTQRLIRVITDTIYELMVWVAVLHNRQTRGRFNIAAGDLAKMHRFATIR
MSMEG_0816|M.smegmatis_MC2_155 PLTQRVVRAITDAIYAFMVDTAVLKHRYFR-RLNIAAADLGRLHLAASIR
MAV_2172|M.avium_104 PAAQRALRWVTDVLLEIIMIVGALHFKESRGRGNISASDLAKINRFRWIR
MAB_2477c|M.abscessus_ATCC_199 PRTQKIARTVGSAILEVIMVGGVLHFRQFR-QANHGASLLAKAHLFAQVR
TH_4080|M.thermoresistible__bu PGLRLALRGGIYALQEALAVGMTKYPGMLR-----IGHLLGKWNINRSVK
MLBr_00065|M.leprae_Br4923 KYAYTAVRWKNILRQSALYGACQKWPQRMR---NILLGHVARRLPKGYDV
* .:
Mb1428c|M.bovis_AF2122/97 DPVVREQLTPRYAVGCKRPGFHNTYLSTFNRDNVRLVTEPIDKITPTAVA
Rv1393c|M.tuberculosis_H37Rv DPVVREQLTPRYAVGCKRPGFHNTYLSTFNRDNVRLVTEPIDKITPTAVA
MUL_1793|M.ulcerans_Agy99 DPVVRDQLTPRYAVDCKRPGFHNGYLSTFNRDNVQLVTEPIEKITPTSVA
MMAR_3138|M.marinum_M DPVTRDQLIPRYSLGCKRPSFHNSYLATYNRRNVSLETSGITHVDHASVH
Mflv_0184|M.gilvum_PYR-GCK DKDLRRRLTPDYDFGCKRPTFSNSYYRTFTKPHVHLQDTGIARVESDGIV
Mvan_0721|M.vanbaalenii_PYR-1 DKELRAKLTPDYDFGCKRPTFSNSYYRTFTKPHVHLQDSGIARIESDGIV
MSMEG_0816|M.smegmatis_MC2_155 DPDLRSKLTPDYDFGCKRPTFSNSYYRTFTKPHVHLQADGIDHVEPDGIV
MAV_2172|M.avium_104 DKELRAKLTPDYDCGCKRPTFSNSFYRVLTQPNVHLETNPIERIEPDGIV
MAB_2477c|M.abscessus_ATCC_199 DRELRRKLTPDYDFGCKRPTFSNTYFRAFTKKNVSLETASIARIEADGIV
TH_4080|M.thermoresistible__bu DPQLRAKLTPDYRLGCKRILNSSTYYPAVADPRTEVITESIDRITTDGIV
MLBr_00065|M.leprae_Br4923 QKHFGPHYNPWEQRLCLVP--DGDLFRAIRKGTVDMVTDAIDRFTSTGIR
: : * * . . . : * :. .:
Mb1428c|M.bovis_AF2122/97 TTDGASHEIDVLVLATGFKVLDTDSIPTYAVTGTGGASLSRFWDEHRLQA
Rv1393c|M.tuberculosis_H37Rv TTDGASHEIDVLVLATGFKVLDTDSIPTYAVTGTGGASLSRFWDEHRLQA
MUL_1793|M.ulcerans_Agy99 TDDGTDHEIDVLILATGFKVLDTDDVLTYPVIGRAGRSLSQFWEEHRAQA
MMAR_3138|M.marinum_M TEDGKSYPIDVMVLATGFKVMESGNMPTYVLKGRGGVEQSAWWDEHRLQA
Mflv_0184|M.gilvum_PYR-GCK AGDGTKTVIDTLVLATGFDLWEAN-FPAIEVIGRDGRNLGKWWRETRFQA
Mvan_0721|M.vanbaalenii_PYR-1 GNDGTKTPIDTLVLATGFDLWEAN-FPAIEVIGRDGRNLGKWWRETRFQA
MSMEG_0816|M.smegmatis_MC2_155 NADGSKTVIDTLVLATGFDLWEAN-FPAIEVIGRQGRDLGKWWRETRFQA
MAV_2172|M.avium_104 TADGRKNVIDTLVLATGFDLWEAN-FPAIEVIGRKGRNLGKWWRETRFQA
MAB_2477c|M.abscessus_ATCC_199 TADGRKTVIDTLVLATGFNLWEST-FPAFEVIGREDYNLGKFWRDNRFQA
TH_4080|M.thermoresistible__bu TSDGTERAVDVIVYATGFHVSDSY--KYVQIKGLNGEDIVDRFNREGPMA
MLBr_00065|M.leprae_Br4923 LKSGNELRADIIVTATGLNLQLFG--------GAVATVDGQPVDLAQTMS
.* . * :: ***:.: * :
Mb1428c|M.bovis_AF2122/97 YEGVSVPGYPNFFTVFGPYGYVGS-SYFALIETQAHHIIRCLKRARRTGA
Rv1393c|M.tuberculosis_H37Rv YEGVSVPGYPNFFTVFGPYGYVGS-SYFALIETQAHHIIRCLKRARRTGA
MUL_1793|M.ulcerans_Agy99 YQGVSVPGYRNFFAVFGPYGYVGS-SYFALIETQTHHILRCLKRARRDGA
MMAR_3138|M.marinum_M FEGVSVPGFPNHFNIFGPYGYNGS-SYFTLIEAQSRHIVRCLRRARTLKA
Mflv_0184|M.gilvum_PYR-GCK YQGVSIPYFPNYLSLASPYAFIGL-NFFNTMEYQMRLMDRLFGELRRRGA
Mvan_0721|M.vanbaalenii_PYR-1 YQGVSMPHFPNFLSLASPFAFLGL-NFFNTVEYQMRHMDRLFGELRRRGA
MSMEG_0816|M.smegmatis_MC2_155 YQGVSMPYFPNYLSLAGPYAFLGL-NFFNTMEYQMRLMERLLGEVARRDA
MAV_2172|M.avium_104 YQGVSMPYFPNYLSLASPFAFSGL-SFFHTIEYQMRHMDRLLGEVKRRGA
MAB_2477c|M.abscessus_ATCC_199 FEGIAVPKFPNLLTLNGPYSYSGL-SYFDTIESQMRHIKRLFAEMARTGT
TH_4080|M.thermoresistible__bu HRGTAVADLPNAYLLLGPNTGLGHNSMVYMIESQINYVIEAIKAVDKAGA
MLBr_00065|M.leprae_Br4923 YKGMMLSGLPNMIYTVGYTNASWTLKADLVSEFFCRLLNYMNANDFDTVA
..* :. * . . * . : :
Mb1428c|M.bovis_AF2122/97 TRIEVTEEANARYFAEVMRRRHRQVFWQDSCRLANSYYFDKNGD-VPLRP
Rv1393c|M.tuberculosis_H37Rv TRIEVTEEANARYFAEVMRRRHRQVFWQDSCRLANSYYFDKNGD-VPLRP
MUL_1793|M.ulcerans_Agy99 TRVEVTEEANARYFAEMMRRRYRQVFWQDSCRRANSYYFDKNGD-VPLRP
MMAR_3138|M.marinum_M DYVEVRQQANDRYFGDMVSRRHRQVFWQPSCSNANSYYFDKHGD-VPLRP
Mflv_0184|M.gilvum_PYR-GCK TTFEVTEEANAEFLDRMTDLLGESLFTIGNCASARSYYFNPAGEPTLLRP
Mvan_0721|M.vanbaalenii_PYR-1 TTFEITEEANARYLARMTALLGDSLFTNGSCATARSYYFNPSGEPTLLRP
MSMEG_0816|M.smegmatis_MC2_155 RTFEVTEEANRRYLDRMTDALGDSLFTLGNCASARSYYFNPSGEATLLRP
MAV_2172|M.avium_104 TTFEVTEEANDRFMERMTKLLDNSVFYAGNCATSRSYYFSPSGEASLLRP
MAB_2477c|M.abscessus_ATCC_199 EVFEVTDEANTEFLDRMTRNLDNSVFYLGSCQTSRSYYFNQHGEAALLRP
TH_4080|M.thermoresistible__bu QALAPTREAQDRYNAELQARLGRSVWNTGGCR---SWYLDEHGNNRVLWG
MLBr_00065|M.leprae_Br4923 VEYPGSDVEERPFMDFTPGYVLRSLDALPKQGSRTPWRLN-QNYLRDIRL
: : .: .: :. . :
Mb1428c|M.bovis_AF2122/97 TTTVEAYWRSRRFDLGDYRISS--------
Rv1393c|M.tuberculosis_H37Rv TTTVEAYWRSRRFDLGDYRISS--------
MUL_1793|M.ulcerans_Agy99 TTTVEAYWRGRHFDLDDYRFGR--------
MMAR_3138|M.marinum_M STTLETYWRSRTFRLSDYRFERRAESVGAR
Mflv_0184|M.gilvum_PYR-GCK TSTETAIREATEFPVTDYSFG---------
Mvan_0721|M.vanbaalenii_PYR-1 TSTRAAIREATDFPIDDYRIV---------
MSMEG_0816|M.smegmatis_MC2_155 MTTRRAVAEASRFPLSDYTFA---------
MAV_2172|M.avium_104 TSTLNSIREASSFPLSDYVIA---------
MAB_2477c|M.abscessus_ATCC_199 TSTASAYKEQESFPLEAYQLA---------
TH_4080|M.thermoresistible__bu GFTWQYRLATRTLDPAEYRFWG--------
MLBr_00065|M.leprae_Br4923 IRRGKVADEGLLFAKKTTPVTV--------
: .