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MPAGLIAAAVRTIVNLGSFGQQFVGVNDPKFTNPEYLAASATGMASDGLTAVFGQTWVPQALAKRVGHSQ LTSLASSKAAQGASAILWTINIVEVLETLMGFGPPAEGDELLVGSTQFAKAQAQLGSALPDNSWQGSASY AYASQNTALQNRGQALAELDVKFAALVKDQAEWVTHGRLGIAILKNLLLAAFAVEMALMFAVPAGPAMAR SFGFTVSGLGIAIAMGLLSTVLTYSVENSKKADVLTANYQDLTPDPYQGADPSMPVAANMPASAESTISS FAASGTAFTAEAAGSLGRASGAADESAFYSAAADEAVPLEDAPSATSAFTMPTLAQLMAISGQGAKFSGH VSQHANLANQAMGQVQQVASMAQQGKGTAPAEDTAQAEATTVEDVEGAGADSAGAAAGRAPIEAAAADTP PAQQPIFAQQVV
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. marinum M | MMAR_1325 | - | - | 100% (432) | hypothetical protein MMAR_1325 |
| M. marinum M | MMAR_5415 | - | 7e-24 | 27.55% (363) | hypothetical protein MMAR_5415 |
| M. marinum M | MMAR_5421 | - | 2e-22 | 28.95% (342) | hypothetical protein MMAR_5421 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3646c | - | 6e-15 | 25.73% (377) | hypothetical protein Mb3646c |
| M. gilvum PYR-GCK | Mflv_0157 | - | 6e-16 | 24.55% (330) | hypothetical protein Mflv_0157 |
| M. tuberculosis H37Rv | Rv3616c | - | 3e-15 | 25.99% (377) | hypothetical protein Rv3616c |
| M. leprae Br4923 | MLBr_00405 | - | 3e-13 | 25.13% (378) | hypothetical protein MLBr_00405 |
| M. abscessus ATCC 19977 | MAB_4336 | - | 9e-05 | 24.15% (207) | acyl-CoA dehydrogenase FadE |
| M. avium 104 | - | - | - | - | - |
| M. smegmatis MC2 155 | MSMEG_0055 | - | 8e-12 | 24.17% (360) | hypothetical protein MSMEG_0055 |
| M. thermoresistible (build 8) | TH_2666 | - | 2e-06 | 26.09% (115) | PUTATIVE putative hypothetical protein MSMEG_0078 |
| M. ulcerans Agy99 | MUL_2554 | - | 0.0 | 99.07% (432) | hypothetical protein MUL_2554 |
| M. vanbaalenii PYR-1 | Mvan_5688 | - | 5e-06 | 27.15% (151) | hypothetical protein Mvan_5688 |
CLUSTAL 2.0.9 multiple sequence alignment
MMAR_1325|M.marinum_M --------------------------------------------------
MUL_2554|M.ulcerans_Agy99 --------------------------------------------------
Mb3646c|M.bovis_AF2122/97 --------------------------------------------------
Rv3616c|M.tuberculosis_H37Rv --------------------------------------------------
MLBr_00405|M.leprae_Br4923 --------------------------------------------------
Mflv_0157|M.gilvum_PYR-GCK --------------------------------------------------
TH_2666|M.thermoresistible__bu --------------------------------------------------
MSMEG_0055|M.smegmatis_MC2_155 --------------------------------------------------
Mvan_5688|M.vanbaalenii_PYR-1 --------------------------------------------------
MAB_4336|M.abscessus_ATCC_1997 MPIAINSEHVALADSAHAFVERVVPTELLHETLETPLPWPPPFWKSAADQ
MMAR_1325|M.marinum_M -------------------------------------------MPAGLIA
MUL_2554|M.ulcerans_Agy99 -------------------------------------------MPAGLIA
Mb3646c|M.bovis_AF2122/97 -------------------------------------------MSRAFII
Rv3616c|M.tuberculosis_H37Rv -------------------------------------------MSRAFII
MLBr_00405|M.leprae_Br4923 -------------------------------------------MSGAFII
Mflv_0157|M.gilvum_PYR-GCK --------------------------------------------------
TH_2666|M.thermoresistible__bu --------------------------------------------------
MSMEG_0055|M.smegmatis_MC2_155 ------------------------------------------MGVLSDVA
Mvan_5688|M.vanbaalenii_PYR-1 -----------------------------------MSLFDDVSGVVGNVV
MAB_4336|M.abscessus_ATCC_1997 GLTSVHLAESVGGQGFGALELAIVVAEFGRGAVPGPFVPSVIASALISAH
MMAR_1325|M.marinum_M AAVRTIVNLGSFGQQFVG-VNDPKFTNPEYLAASATGMASDGLTAVF-GQ
MUL_2554|M.ulcerans_Agy99 AAVRTIVNLGSFGQQFVG-VNDPKFTNPEYLAASATGMASDGLTAVF-GQ
Mb3646c|M.bovis_AF2122/97 DPTISAIDG---LYDLLG-IGIPNQGGILYSSLEYFEKALEELAAAFPGD
Rv3616c|M.tuberculosis_H37Rv DPTISAIDG---LYDLLG-IGIPNQGGILYSSLEYFEKALEELAAAFPGD
MLBr_00405|M.leprae_Br4923 DPTLKAIEA---WHALLG-IGVPNDGGVLYSSLSFFEKALEHLAAAFPGD
Mflv_0157|M.gilvum_PYR-GCK ---MALGKLWVDANYFYG-VADHANMMSSDPALGSAAIATD-AAILMQSL
TH_2666|M.thermoresistible__bu -----MLDAYSTLNWGKS-VVEHPMSAKDHTGWGIAGTGAD-FVTLMQGM
MSMEG_0055|M.smegmatis_MC2_155 DFGKDVIDDRDKWADRFK-KVGHFIERNAKGDRLERVAKFGRALGDFSGK
Mvan_5688|M.vanbaalenii_PYR-1 DVVEGSVGTVESGVDFVGSVLDGDVTGATRDAYEFVDNARDVLGGVRDLG
MAB_4336|M.abscessus_ATCC_1997 DPDHPLLSDLASGASIATFSSTSSFTATPAGDGLSVDGQARSVLSATSAT
MMAR_1325|M.marinum_M TWVPQALAKRVG---HSQLTSLASSKAAQGASAILWTINIVEVLETLMGF
MUL_2554|M.ulcerans_Agy99 TWVPQALAKRVG---HSQLTSLASSKAAQGASAILWTINIVEVLETLMGF
Mb3646c|M.bovis_AF2122/97 GWLGSAADKYAGK--NRNHVNFFQELADLDRQLISLIHDQANAVQTTR--
Rv3616c|M.tuberculosis_H37Rv GWLGSAADKYAGK--NRNHVNFFQELADLDRQLISLIHDQANAVQTTR--
MLBr_00405|M.leprae_Br4923 GWLGSAADKYAGQ--NRKRVDIFQELAELDKELIELIHNQANSVQTTR--
Mflv_0157|M.gilvum_PYR-GCK AAVGGSTMGATGL--ATSVATPIINAGLMTLTAASNTLGFGRPEDGER--
TH_2666|M.thermoresistible__bu TEAG-SGLDQGRL--AKAAATPIIRAALLAMMVMSNTCGVGTPEKGDR--
MSMEG_0055|M.smegmatis_MC2_155 FTDFFESNLGKRM--VKAARSPILAAGQHVITGMKLTTGVGDPENGRR--
Mvan_5688|M.vanbaalenii_PYR-1 VSIGRVPSRFVDNPILELANSPPIELAQRVIAGMRLTTGSGDPVDGEE--
MAB_4336|M.abscessus_ATCC_1997 YVVAPVAIDSDRRWVVLSADDVTLDSQQSVDPLRPVAHVTATAVQVPADR
.
MMAR_1325|M.marinum_M GPP--------------------AEGDELLVGSTQFAKAQAQLGSALPD-
MUL_2554|M.ulcerans_Agy99 GPP--------------------AEGDELLVGSTQFAKAQAQLGSALPD-
Mb3646c|M.bovis_AF2122/97 ---------------------------DILEGAKKGLEFVRPVAVDLTY-
Rv3616c|M.tuberculosis_H37Rv ---------------------------DILEGAKKGLEFVRPVAVDLTY-
MLBr_00405|M.leprae_Br4923 ---------------------------GILDGAKKALLFVRPVAIDLNY-
Mflv_0157|M.gilvum_PYR-GCK ----------------------------FTDGARQFSEANDELQQAVPP-
TH_2666|M.thermoresistible__bu ----------------------------FEEGAQAFEAAGEALGATKSP-
MSMEG_0055|M.smegmatis_MC2_155 ----------------------------FGEGADHMSAAGRTLDSAYPT-
Mvan_5688|M.vanbaalenii_PYR-1 ----------------------------FKNAAKLMQEALELLIDAAPHG
MAB_4336|M.abscessus_ATCC_1997 VLSNLTDARATSIISTIVSAEAVGVARWATDTASEYAKVREQFGRPIGQF
: .
MMAR_1325|M.marinum_M -------------------NSWQGSASYAYASQNTALQNRGQALAELDVK
MUL_2554|M.ulcerans_Agy99 -------------------NSWQGSASYAYASQNTALQNRGQALAELDVK
Mb3646c|M.bovis_AF2122/97 -------------------IPVVG--------------------HALSAA
Rv3616c|M.tuberculosis_H37Rv -------------------IPVVG--------------------HALSAA
MLBr_00405|M.leprae_Br4923 -------------------IPLVG--------------------SVMSAS
Mflv_0157|M.gilvum_PYR-GCK -------------------PDWQG----------------DASDAYGLRN
TH_2666|M.thermoresistible__bu -------------------ESWQG----------------KASNTYTDRN
MSMEG_0055|M.smegmatis_MC2_155 -------------------SDWDS----------------AASDAYLSQN
Mvan_5688|M.vanbaalenii_PYR-1 -------------------DHWSG----------------AASEQYAGAN
MAB_4336|M.abscessus_ATCC_1997 QGIKHKCATMAAVTERATAAVWDAARALDDADENPGVVEFAASVAATLAP
.
MMAR_1325|M.marinum_M FAALVKDQAEWVTHGRLGIAILKNLLLAAFAVEMALMFAVPAGPAMARSF
MUL_2554|M.ulcerans_Agy99 FAALVKDQAEWATHGRLGIAILKNLLLATFAVEMALMFAVPAGPAMARSF
Mb3646c|M.bovis_AF2122/97 FQAPFCAGAMAVVGGALAYLAVKTLINATQLLKLLAKLAELVAAAIAD--
Rv3616c|M.tuberculosis_H37Rv FQAPFCAGAMAVVGGALAYLVVKTLINATQLLKLLAKLAELVAAAIAD--
MLBr_00405|M.leprae_Br4923 IQAQACAAAMAAVSGGLAYLLVQTAIHTAKFVALLARLAHLLASAVAD--
Mflv_0157|M.gilvum_PYR-GCK TEQQQRAGSMATFDGQIQEVLAEEAGQVQDTRDFVSTRQVMLAAAIPA--
TH_2666|M.thermoresistible__bu DEQRARAERMAAIDRTVKEILDAEAHQVDVARKMLDRCQTVLSLSIPA--
MSMEG_0055|M.smegmatis_MC2_155 NGQVTRAEALVHADQVVAAVLSREAEQIATTREVLDSEADWLGDMSLV--
Mvan_5688|M.vanbaalenii_PYR-1 TQNRRATSGVQVADWNIADFLEAEAEQVMRTRKTLDDINEYLFQFALS--
MAB_4336|M.abscessus_ATCC_1997 AAAQQCAQDCIQVHGGIGYTWEHDAHIYYRRALGLTAALGRSGGAPATVV
:
MMAR_1325|M.marinum_M --------------GFTVSGLGIAIAMGLLSTVLTYSVENSKKADVLTAN
MUL_2554|M.ulcerans_Agy99 --------------GFTVSGLGIAIAMGLLSTVLTYSVENSKKADVLTAN
Mb3646c|M.bovis_AF2122/97 -----------------IISDVADIIKGILGEVWEFITNALNGLKELWDK
Rv3616c|M.tuberculosis_H37Rv -----------------IISDVADIIKGTLGEVWEFITNALNGLKELWDK
MLBr_00405|M.leprae_Br4923 -----------------VVSDGVAIIKGIVDHLWHFIAGALTGLKDIVEK
Mflv_0157|M.gilvum_PYR-GCK -----------------AITAKLIPPGGAAAAMAIELAAVAATVPFAMQR
TH_2666|M.thermoresistible__bu -----------------AIAAKAIPFKGPAISTAIEVAAVAGTAPLASLR
MSMEG_0055|M.smegmatis_MC2_155 -----------------TMATGLIPYVGRAAQTAAEIAMVTKAVGASTDQ
Mvan_5688|M.vanbaalenii_PYR-1 ------------------TAWMNGIPGGRAAKLVVDATAAAGGALSAERA
MAB_4336|M.abscessus_ATCC_1997 RTAVEHGLRKVDIDLAPETEALRAEIRAEVAALKEIPSGKRNTAIAEGGW
.
MMAR_1325|M.marinum_M YQDLTPDPYQGADPSMP-V--------------------------AANMP
MUL_2554|M.ulcerans_Agy99 YQDLTPDPYQGADPSMP-M--------------------------AANMP
Mb3646c|M.bovis_AF2122/97 LTGWVTGLFSRGWSNLESF--------------------------FAGVP
Rv3616c|M.tuberculosis_H37Rv LTGWVTGLFSRGWSNLESF--------------------------FAGVP
MLBr_00405|M.leprae_Br4923 IIHWFFGLFSHWWSRLHSF--------------------------FGGIP
Mflv_0157|M.gilvum_PYR-GCK VTEMVSHSADN---------------------------------------
TH_2666|M.thermoresistible__bu YNELTRAVIRN---------------------------------------
MSMEG_0055|M.smegmatis_MC2_155 FMMMRDKADENAAEVRDAIGKYEAVAGDADDTTADDTAGDAPESEPTAAE
Mvan_5688|M.vanbaalenii_PYR-1 LLTLVADSVERGGK------------------------------------
MAB_4336|M.abscessus_ATCC_1997 VLPYLPTPWGRAASPVEQVIISQEFLTGKVRRPQLGIATWLVPSIVAYGT
MMAR_1325|M.marinum_M ASAESTISSFAASGTAFTAEAAGSLGRASGAADESAFYSAAAD-----EA
MUL_2554|M.ulcerans_Agy99 ASAESTISSFAASGTAFTAEAAGSLGRASGAADESAFYSAAAD-----EA
Mb3646c|M.bovis_AF2122/97 GLTG------ATSGLSQVTGLFGAAGLSASSGLAHADSLASSA-----SL
Rv3616c|M.tuberculosis_H37Rv GLTG------ATSGLSQVTGLFGAAGLSASSGLAHADSLASSA-----SL
MLBr_00405|M.leprae_Br4923 GLSG------ATSGLSQVTGLFGVPGLAGSSGLLSGESLLSTE-----NL
Mflv_0157|M.gilvum_PYR-GCK -----------ADRIRQIGSHYGVVDESAQMPGG--LSGAQSG-----TP
TH_2666|M.thermoresistible__bu -----------AARMTQAAGEYSSVASAANPS------------------
MSMEG_0055|M.smegmatis_MC2_155 DSSETSKEDGQSRHENPVAAPSGGGGGATSGGGGGAPSSASSA-----GP
Mvan_5688|M.vanbaalenii_PYR-1 ----------IRDQFNLYEGAANQERKLDDPTCDGPFVPAKVD-----RS
MAB_4336|M.abscessus_ATCC_1997 EEQKQRFLPPTFRGEMMWCQLFSEPGAGSDLAGLSTKAVKVEGGWRLTGQ
.
MMAR_1325|M.marinum_M VPLEDAPSATSAFTMPTLAQLMAISGQGAKFS------------------
MUL_2554|M.ulcerans_Agy99 VPLEDAPSATSAFTMPTLAQLMAISGQGAKFS------------------
Mb3646c|M.bovis_AF2122/97 PALAGIGGGSGFGGLPSLAQVHAASTRQALRP------------------
Rv3616c|M.tuberculosis_H37Rv PALAGIGGGSGFGGLPSLAQVHAASTRQALRP------------------
MLBr_00405|M.leprae_Br4923 PSLAGVGAGLGLGSLPQLAQLHAASTRQGTRS------------------
Mflv_0157|M.gilvum_PYR-GCK APLRVSESIRGTAGIQQNVAATIDSARSAPDG------------------
TH_2666|M.thermoresistible__bu --------------------------------------------------
MSMEG_0055|M.smegmatis_MC2_155 AGTPQVPSPPGFGAANTPTDAQPGAAAASDAAGMLGSVMGAMLGPLGGIV
Mvan_5688|M.vanbaalenii_PYR-1 DAGRPGRFDNPHYTVPTPVEPPQHGPAATPYIG-----------------
MAB_4336|M.abscessus_ATCC_1997 KIWTSVAQFADWGACLARTDPSAPKHNGITYFLVDMKSEGVTVRPLREMT
MMAR_1325|M.marinum_M GHVSQHANLANQAMGQVQQVASMAQQGKGTAPAEDTAQAEATTVED----
MUL_2554|M.ulcerans_Agy99 GHVSQHANLANQAMGQVQQVASMAQQGKGTAPAEDTAQTEATTVED----
Mb3646c|M.bovis_AF2122/97 RADGPVGAAAEQVGGQSQLVSAQGSQGMGGPVGMGGMHPSSGASKG----
Rv3616c|M.tuberculosis_H37Rv RADGPVGAAAEQVGGQSQLVSAQGSQGMGGPVGMGGMHPSSGASKG----
MLBr_00405|M.leprae_Br4923 QAGVSAELSTEQFGGQQEPVSAQGSQGMGGSQGMGGMTPASTKSKKD---
Mflv_0157|M.gilvum_PYR-GCK SAGDVFKTHGVVCTSTAAALKSAELARRSAAEKMHLISTDLSAKLG----
TH_2666|M.thermoresistible__bu --------------------------------------------------
MSMEG_0055|M.smegmatis_MC2_155 GGVVQAAGQALQAATQAGAQAAQLAGQAAAAPDVDRADTDEDTDKDPDAE
Mvan_5688|M.vanbaalenii_PYR-1 GGSSVPMPAPQSTSRTAHPQGSAPRPWAGTNPTAAPASPTPQPTGAP---
MAB_4336|M.abscessus_ATCC_1997 GGALFNEVFIDDVFVPDELVVGEVNRGWEVSRNTLTAERVSIGSSDLPFL
MMAR_1325|M.marinum_M --VEGAGADSAGAAAGRAPIEAAAADTPP-AQQPIFAQQVV---------
MUL_2554|M.ulcerans_Agy99 --VEGAGADSAGAAAGRAPIEAAAADTPP-AQQPIFAQQVV---------
Mb3646c|M.bovis_AF2122/97 ---TTTKKYSEGAAAGTEDAERAPVEADAGGGQKVLVRNVV---------
Rv3616c|M.tuberculosis_H37Rv ---TTTKKYSEGAAAGTEDAERAPVEADAGGGQKVLVRNVV---------
MLBr_00405|M.leprae_Br4923 --ERKKKKYSEGAAAGTDDAERAPIEVQSGGGKRALAQHVV---------
Mflv_0157|M.gilvum_PYR-GCK ---SSATEYSHTEQQNADAVDRQMPPR-----------------------
TH_2666|M.thermoresistible__bu --------------------------------------------------
MSMEG_0055|M.smegmatis_MC2_155 GDKDSDKRDGEGKEDGTAPRDRESTDAMGADDDDRNAHPQAGSGTDSAGE
Mvan_5688|M.vanbaalenii_PYR-1 ---GTRTGSLPGQGAGNRGAAPLRVTARPTSDDKSQEIPT----------
MAB_4336|M.abscessus_ATCC_1997 ASLDDLVAFVGTHDLGEVARDRAGQLIAEGHGVKLLNLRSTLLTLAGGDP
MMAR_1325|M.marinum_M --------------------------------------------------
MUL_2554|M.ulcerans_Agy99 --------------------------------------------------
Mb3646c|M.bovis_AF2122/97 --------------------------------------------------
Rv3616c|M.tuberculosis_H37Rv --------------------------------------------------
MLBr_00405|M.leprae_Br4923 --------------------------------------------------
Mflv_0157|M.gilvum_PYR-GCK --------------------------------------------------
TH_2666|M.thermoresistible__bu --------------------------------------------------
MSMEG_0055|M.smegmatis_MC2_155 DDKKPAMTLPPDLQAASALDTGAGSAPVHVGADFEHSQLRTVAAATLDHG
Mvan_5688|M.vanbaalenii_PYR-1 --------------------------------------------------
MAB_4336|M.abscessus_ATCC_1997 MPSAAVSKLLGMRTGQGYAEFVVNHFGQDGAIGDSEQEQGRWADYLLASR
MMAR_1325|M.marinum_M ---------------------------
MUL_2554|M.ulcerans_Agy99 ---------------------------
Mb3646c|M.bovis_AF2122/97 ---------------------------
Rv3616c|M.tuberculosis_H37Rv ---------------------------
MLBr_00405|M.leprae_Br4923 ---------------------------
Mflv_0157|M.gilvum_PYR-GCK ---------------------------
TH_2666|M.thermoresistible__bu ---------------------------
MSMEG_0055|M.smegmatis_MC2_155 IPGSAAARGA-----------------
Mvan_5688|M.vanbaalenii_PYR-1 ---------------------------
MAB_4336|M.abscessus_ATCC_1997 ATTIYGGTSEVQLNIIAERLLGLPRDP