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ATDAEGVAVGWSTRELADLAGTSLRTVRHYHDVGLLGEPERRPNGYKSYGVAHLVRVLQIKRLTGLGLSL KQIAEMDEADENQQEALRALDAELAATIDRLQGVRDELAQIFSSEIAADLPREFGAAAVDMNFSETDRSL AFVMSRVLGPAGLQAFVGMFLDQQDRALDHELENLPADAGERTRADLAERMSLHAKRLYADHPGMLNSTA DAPRGQRFAESTVARALLDLFNPAQLDVLIRVGAAVRSEPGEG*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. abscessus ATCC 19977 | MAB_4723c | - | - | 100% (254) | MerR family transcriptional regulator |
| M. abscessus ATCC 19977 | MAB_4270c | - | 8e-05 | 34.44% (90) | heat shock protein transcriptional regulator HspR |
| M. abscessus ATCC 19977 | MAB_2246 | - | 8e-05 | 29.69% (128) | thiol-specific antioxidant related protein/peroxidoxin BcpB |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3367 | - | 1e-07 | 33.66% (101) | MerR family transcriptional regulator |
| M. gilvum PYR-GCK | Mflv_0148 | - | 2e-08 | 28.21% (234) | MerR family transcriptional regulator |
| M. tuberculosis H37Rv | Rv3334 | - | 1e-07 | 33.66% (101) | MerR family transcriptional regulator |
| M. leprae Br4923 | - | - | - | - | - |
| M. marinum M | MMAR_0009 | - | 1e-06 | 24.77% (222) | transcriptional regulator |
| M. avium 104 | - | - | - | - | - |
| M. smegmatis MC2 155 | MSMEG_4397 | - | 2e-08 | 39.33% (89) | transcriptional regulator, MerR family protein |
| M. thermoresistible (build 8) | TH_3036 | - | 1e-05 | 35.44% (79) | PUTATIVE putative transcriptional regulator, MerR family |
| M. ulcerans Agy99 | MUL_0011 | - | 1e-06 | 24.32% (222) | transcriptional regulator |
| M. vanbaalenii PYR-1 | Mvan_1919 | - | 2e-07 | 25.47% (212) | MerR family transcriptional regulator |
CLUSTAL 2.0.9 multiple sequence alignment
Mb3367|M.bovis_AF2122/97 ------------------MKISEVAALTNTSTKTLRFYENSGLLPPPART
Rv3334|M.tuberculosis_H37Rv ------------------MKISEVAALTNTSTKTLRFYENSGLLPPPART
MMAR_0009|M.marinum_M ---------------MDGLTVGQVAERFGITVRTLHHYDEIGLLIPSRRA
MUL_0011|M.ulcerans_Agy99 ---------------MDGLTVGQVAERFGITVRTLHHYDEIGLLIPSRRA
Mvan_1919|M.vanbaalenii_PYR-1 MTSGTTLTYVTQEMQVDELTVGEVAERFGITVRTLHHYDEIGLLTPGRRC
Mflv_0148|M.gilvum_PYR-GCK ---------MTQETRMEELTVGEVAKRFGITIRTLHHYDHIGLLTPEQRN
MSMEG_4397|M.smegmatis_MC2_155 ------------------MRIGELAERTGVSRRQLRYYEEQGLLMPN-RA
MAB_4723c|M.abscessus_ATCC_199 -------MATDAEGVAVGWSTRELADLAGTSLRTVRHYHDVGLLGEPERR
TH_3036|M.thermoresistible__bu ---------------LTEYRLEELAEISGVSPRNIRAYRERGLLGAPRRQ
::* . : : :: * . *** *
Mb3367|M.bovis_AF2122/97 ASGYRNYGPEIVDRLRFIHRGQAAGLALQEVRQILAIHD----------R
Rv3334|M.tuberculosis_H37Rv ASGYRNYGPEIVDRLRFIHRGQAAGLALQEVRQILAIHD----------R
MMAR_0009|M.marinum_M ASGYRVYTSADLTRLSQVIVYRRLELPLDEIARLLDEGNAVSHLVRQRER
MUL_0011|M.ulcerans_Agy99 ASGYRVYTSADLTRLSQVIVYRRLELPLDEIARLLDEGNAVSHLVRQRER
Mvan_1919|M.vanbaalenii_PYR-1 ASGYRVYTPADLTRLSQVIVYRRLDFSLDEIASLLDEGNEVSHLIRQRER
Mflv_0148|M.gilvum_PYR-GCK ASGYRVYTSADLTRLSQIIVYRRLEMSLDEIASVLDEGDEISHLRRQRER
MSMEG_4397|M.smegmatis_MC2_155 ANGYREYGEAHVHVVLQIAGLLDAGLPTRIIEQLLPCLD-----------
MAB_4723c|M.abscessus_ATCC_199 PNGYKSYGVAHLVRVLQIKRLTGLGLSLKQIAEMDEADENQQEALRALDA
TH_3036|M.thermoresistible__bu GR-SAFYNDAHLAQLRMIDRLLRRGFNSVHIAEFFAAVREGKDLADVLEL
* : : : : : .
Mb3367|M.bovis_AF2122/97 GEAPCAHVRQLLSTRIDEVRAQIAELIALEGHLQTLLDH-----------
Rv3334|M.tuberculosis_H37Rv GEAPCAHVRQLLSTRIDEVRAQIAELIALEGHLQTLLDH-----------
MMAR_0009|M.marinum_M VMARLDEMKDLVEAIDQALEKAMTNTPMTDDDMRELFGDGFDDYRAETEQ
MUL_0011|M.ulcerans_Agy99 VMARLDEMKDLVEAIDLALEKAMTNTPMTDDDMRELFGDGFDDYRVETEQ
Mvan_1919|M.vanbaalenii_PYR-1 VMSRLDEMKDLVAAIDQALEKAMTNTPMTDDDMRELFGDGFDDYQAEAEQ
Mflv_0148|M.gilvum_PYR-GCK VMSRLDELTELVGAIDQALENAMTNTPMTDDDMRELFGDSFDDYQAEAEQ
MSMEG_4397|M.smegmatis_MC2_155 -QPQTIYVPNVTPEMVATLQREQARLTERIECLAR---------------
MAB_4723c|M.abscessus_ATCC_199 ELAATIDRLQGVRDELAQIFSSEIAADLPREFGAAAVDMNFSETDRSLAF
TH_3036|M.thermoresistible__bu DRSVLESPRLASQDAAAAILDLDPMGAEAHRLVEYGLARRVQDGRREGIV
. :
Mb3367|M.bovis_AF2122/97 ---------------ASYG-------------------------------
Rv3334|M.tuberculosis_H37Rv ---------------ASYG-------------------------------
MMAR_0009|M.marinum_M KWGETTEWKESQRRTRSYGKDEWVRIKAEGQAVEKTLSDAFRAGLPADSE
MUL_0011|M.ulcerans_Agy99 KWGETAEWKESQRRTKSYGKDEWVRIKAEGQAIEKALSDAFRAGLPADSE
Mvan_1919|M.vanbaalenii_PYR-1 KWGETAEWKESQRRTKSYGKDEWVQIKSEGEAVEKALSDAFRAGLPPDSA
Mflv_0148|M.gilvum_PYR-GCK KWGETAEWKESQRRATSYGKDDWVRIKAEGQAVEKALADAFRAGLPADSE
MSMEG_4397|M.smegmatis_MC2_155 --------------------------------------------------
MAB_4723c|M.abscessus_ATCC_199 VMSRVLGPAGLQAFVGMFLDQQDRALDHELENLPADAGERTR--------
TH_3036|M.thermoresistible__bu LTDPVLADVVRHSPVSHLGYVHVLLRVFEAVR------------------
Mb3367|M.bovis_AF2122/97 ----PPTEHDHSTVCWILES--------------------------DLDE
Rv3334|M.tuberculosis_H37Rv ----PPTEHDHSTVCWILES--------------------------DLDE
MMAR_0009|M.marinum_M EAMNAAEQHRRHVNRWFYDCPPAFHRSLGDMYVSDPRYIATYDESFGLPG
MUL_0011|M.ulcerans_Agy99 EAMNAAEQHRRHVNRWFYDCPPAFHRNLGDMYVSDPRYIATYDESFGLPG
Mvan_1919|M.vanbaalenii_PYR-1 EAMNAAEQHRLHVNRWFYDCPPAFHRKLGDMYVSDPRYVATYDESFGLPG
Mflv_0148|M.gilvum_PYR-GCK EAMNAAEQHRHHVNRWFYDCPPAFHRTLGDMYVSDPRYVATYDESFGLPG
MSMEG_4397|M.smegmatis_MC2_155 ----NRDAIAAYLDT-------------------------------VLSV
MAB_4723c|M.abscessus_ATCC_199 --ADLAERMSLHAKRLYADHPGMLNSTADAPRGQRFAESTVARALLDLFN
TH_3036|M.thermoresistible__bu ---EGVDRLAAAAGAAPAATVDAGRNGGATVAPGASRVERVLADYRRLVG
*
Mb3367|M.bovis_AF2122/97 PTAIEVSDIHA----------
Rv3334|M.tuberculosis_H37Rv PTAIEVSDIHA----------
MMAR_0009|M.marinum_M LAAYCREAIHANANRTGG---
MUL_0011|M.ulcerans_Agy99 LAAYCREAIHANANRAGG---
Mvan_1919|M.vanbaalenii_PYR-1 LAAYCREAIHANADRAGQ---
Mflv_0148|M.gilvum_PYR-GCK LARYCRDAIHANADRS-----
MSMEG_4397|M.smegmatis_MC2_155 RSANLARERQGS---------
MAB_4723c|M.abscessus_ATCC_199 PAQLDVLIRVGAAVRSEPGEG
TH_3036|M.thermoresistible__bu RVVSRYLDEVSARLPVSRPRP
.