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MHISLHGGKGFANLTRRRRPSSASVLLVAGFGAFLAFLDSTIVNIAFPDIQRSFPSYDIGSLSWILNGYN IVFAAFMVAAGRLADLLGRRRTFLSGVLVFTIASGLCAVAGSVEQLVAFRVLQGIGAAILVPASLALVVE GFDAARRAHAIGLWGAAAAIAAGLGPPIGGLLVEWAGWRWVLLVNVPLGIVAAIATKRMLVESRASGRRR MPDLRGALLLAVTLGLVTLGLVKGPDWGWLSVATVGSFLASVLTSVGFVHSSRSHPAPLVEPALLRSRSF VAGNLLTLVAAAGFYCYGLTHVLYLNYVWHYSLLKAGFAIAPAAVVAAVVAAALGRVAGRHGHRVIVLVG ALVWAGSLVWYLQRVGSEPDFLRVWLPGQLLQGIGVGATLPVLSSAALAEVAKGGSYATSSAVVSTTRQL GAVLGVAVMVILIGKPEHGTAEEALRRGWAMAAICFIAVAVAAAVLGRTNRNPVQMPAPEPAIAPRLEPP IPQPAAAPIEHWAAGDADPLGNLPLFAGLDAATLAQLGEHVEDVELEAGCYLFHEGDPSDSLYVIRTGRV QVLQDSIVLKELGRGEVLGELGLLIDAPRSATVRALRDTKLVRLTKAQFDEIADHGALAALVKVLATRLR EAPPPATDSTSPEVVVSVIGVSGDAPVPAVAAGLLTALSARLRAVDPGRVDRDGLDRAERVADKVVLHAA VEDAGWRDFCLRVADRIVLVAGDPNPQAARLPARARGADLVLAGPAASREHRRQWEELITPRSVHVVHYR RILENVRPLAARIAGRSIGLVLGGGGARGFAHLGVLDELERVGVTIDRFAGTSMGAVIAVFGACGMDAAT ADAYAYEYFIRHNPLSDYAFPVRGLVHGRRTLTLLEAAFGDRLVEELPKEFRCVSVDLLARRPVVHRRGR LVDVIGCSLRLPGIYPPQVYNGRLHVDGGVLDNLPVSTRASPDGPLIAVSIGLGGGGPGSARQDGSPKVP GIGDTLMRTMTIGSQRGADAALSLAQVVIRPDTGAVGLLEFHQIDAAREAGRVAAREAMPHIMALLNR
Operon Prediction Model: Genebank
Paralogs
species | id | gene | e-value | identity (len) | annotation |
M. bovis AF2122 / 97 | Mb3267c | - | - | 100% (1048) | transmembrane transport protein |
M. bovis AF2122 / 97 | Mb3755 | - | 0.0 | 63.96% (1046) | hypothetical protein Mb3755 |
M. bovis AF2122 / 97 | Mb2594 | - | 2e-75 | 35.89% (574) | hypothetical protein Mb2594 |
Closest Orthologs (e-value cutoff: 1e-4)
species | id | gene | e-value | identity (len) | annotation |
M. gilvum PYR-GCK | Mflv_0301 | - | 1e-56 | 33.41% (443) | EmrB/QacA family drug resistance transporter |
M. tuberculosis H37Rv | Rv3239c | - | 0.0 | 99.90% (1048) | transmembrane transport protein |
M. leprae Br4923 | MLBr_01562 | - | 8e-48 | 30.83% (412) | putative transmembrane efflux protein |
M. abscessus ATCC 19977 | MAB_0945 | - | 4e-51 | 31.35% (453) | EmrB/QacA family drug resistance transporter |
M. marinum M | MMAR_1306 | - | 0.0 | 80.13% (1047) | transmembrane transport protein |
M. avium 104 | MAV_3702 | - | 7e-47 | 32.05% (415) | transporter, major facilitator family protein |
M. smegmatis MC2 155 | MSMEG_5670 | - | 2e-55 | 30.79% (484) | efflux membrane protein |
M. thermoresistible (build 8) | TH_3965 | - | 2e-47 | 32.03% (409) | PUTATIVE drug transporter |
M. ulcerans Agy99 | MUL_3590 | - | 0.0 | 70.64% (1039) | transmembrane transport protein |
M. vanbaalenii PYR-1 | Mvan_4014 | - | 2e-51 | 31.01% (445) | EmrB/QacA family drug resistance transporter |
CLUSTAL 2.0.9 multiple sequence alignment Mb3267c|M.bovis_AF2122/97 -----------------------------------MHISLHGGKGFANLT Rv3239c|M.tuberculosis_H37Rv -----------------------------------MHISLHGGKGFANLT MMAR_1306|M.marinum_M ---------MSGVSISSFEKVTSRHSKRPGATPARTHLAGHARKGFANLT MUL_3590|M.ulcerans_Agy99 -----------------------------------MHLSAPAER--SALT TH_3965|M.thermoresistible__bu ------------------------------VTSVDAGRSTMSEVFTAYAP Mvan_4014|M.vanbaalenii_PYR-1 --------------------------------------MSQHRPHDAIAA MAB_0945|M.abscessus_ATCC_1997 --------------------------------------------MEAAVG MSMEG_5670|M.smegmatis_MC2_155 --------------------------------------------MNETVG Mflv_0301|M.gilvum_PYR-GCK --------------------------------------------MTGLRM MLBr_01562|M.leprae_Br4923 MVTLYDHERAVHNWTAARSDRPAPSRLTQQVE----PASERTSKYPTLLP MAV_3702|M.avium_104 MTALNDSERAVQNWTSARPDRPAPVRSTPPAETAPKPAAETAVKRTSKYY Mb3267c|M.bovis_AF2122/97 RRRRPSSASVLLVAGFG--AFLAFLDSTIVNIAFPDIQRSFPSYDIGSLS Rv3239c|M.tuberculosis_H37Rv RRRRPSSASVLLVAGFG--AFLAFLDSTIVNIAFPDIQRSFPSYDIGSLS MMAR_1306|M.marinum_M HRRQPSSAAVLLVAAFG--AFLAFLDSTIVNIAFPDIQKSFPSYDLGSLS MUL_3590|M.ulcerans_Agy99 SRRQPSATAVLLVASFG--AFLAFLDSTIVNIAFPHIQRSFPSYDISSLS TH_3965|M.thermoresistible__bu RSAAANPWHALWAMLIG--FFMILVDATIVPVANLEIMADLG-ADYTAVI Mvan_4014|M.vanbaalenii_PYR-1 EPTDDHPFRALWVMMVG--FFLIVVDSTVIAVANPVLKNDFD-VEYHSVI MAB_0945|M.abscessus_ATCC_1997 ALSERRKIVILGSCCLS--LLIVSMDSTIVNVALPTIRADFG-ATTSQLQ MSMEG_5670|M.smegmatis_MC2_155 ALSARRKAIILVSCCLS--LLIVSMDATIVNVAIPSIRSDLG-ASPSQLQ Mflv_0301|M.gilvum_PYR-GCK GTAAGR--WVLLATVLG--SGIVMVDATVVNVALPHIAADLG-GGFGDLQ MLBr_01562|M.leprae_Br4923 SGRFPSGRFIAAVIVIGGMQLLATMDSTVAIVALPKIQNELSLSDAG-RS MAV_3702|M.avium_104 PAWLPSRRFIAAVIAIGGMQLLATMDSTVAIVALPRIQNELSLSDAG-RS .. : :*:*: :* : .: Mb3267c|M.bovis_AF2122/97 WILNGYNIVFAAFMVAAGRLADLLGRRRTFLSGVLVFTIASGLCAVAGSV Rv3239c|M.tuberculosis_H37Rv WILNGYNIVFAAFMVAAGRLADLLGRRRTFLSGVLVFTIASGLCAVAGSV MMAR_1306|M.marinum_M WILNAYNIVFAAFLVAAGRMADLLGRRRTFTFGVVIFTIASGLCAVAGSV MUL_3590|M.ulcerans_Agy99 WILNGYNIVFAAFLVASGRLADVLGRKRMFVFGVVLFTIASGLCAVAGDV TH_3965|M.thermoresistible__bu WVTSAYLLAYAVPLLIAGRLGDRFGPRTMYLIGLAIFTAASLWCGLAGTI Mvan_4014|M.vanbaalenii_PYR-1 WVTSGYLLAFAAFLLIGGRLGDRFGSKPVYLVGLTLFAAASVWCGLSTSV MAB_0945|M.abscessus_ATCC_1997 WVIDIYTLGLASLLMLSGAAGDRLGRRKVFHLGLSIFAIGSLLCSVAPTV MSMEG_5670|M.smegmatis_MC2_155 WVIDVYTLVLASLLLLAGATGDRFGRRRTFHLGLTVFAVASLLCSVAPNI Mflv_0301|M.gilvum_PYR-GCK WVVNAYTLTLASLILLGGSLGDHFGRRKVFVLGVVWFALASIACGLAPSI MLBr_01562|M.leprae_Br4923 WGITAYVLTFGGLMLLGGRLGDTIGRKRTFIVGVALFTISSVLCAVAWDE MAV_3702|M.avium_104 WVITAYVLTFGGLMLLGGRLGDTIGRKRTFIVGVALFTISSVLCAVAWDE * * : . :: .* .* :* : : *: *: .* *.:: Mb3267c|M.bovis_AF2122/97 EQLVAFRVLQGIGAAILVPASLALVVEGFDA-ARRAHAIGLWGAAAAIAA Rv3239c|M.tuberculosis_H37Rv EQLVAFRVLQGIGAAILVPASLALVVEGFDA-ARRAHAIGLWGAAAAIAA MMAR_1306|M.marinum_M EWLVAFRVLQGIGAAVLVPASLALVVEGFEP-ARRAHAVGLWGAAAAIAS MUL_3590|M.ulcerans_Agy99 EQLVGFRVLQGIGAAVLVPASLALVVEGFDA-SHRAHAVGLWGAAAAVAS TH_3965|M.thermoresistible__bu GMLIAARVLQGLGAALLTPQTLSMITRIFPA-DRRGVPMGVWGATAGVAT Mvan_4014|M.vanbaalenii_PYR-1 GMLIAARVAQGVGAALLTPQIMSTITRTFPP-QRHGMAMSVWGATAGVGM MAB_0945|M.abscessus_ATCC_1997 GLLIAARLLQAVGGSMLNPVALSIISQVFTGRVERARALGFWGAVVGISM MSMEG_5670|M.smegmatis_MC2_155 ETLIAARLLQAIGGSMLNPVAMSIITQVFTGRVERARAIGVWGSVVGISM Mflv_0301|M.gilvum_PYR-GCK EVLIVARALQGVGGALLTPGSLALISAAFAS-GDRGAAVGAWSGLGGIAG MLBr_01562|M.leprae_Br4923 VTLVIARLLQGIGSAIASPTGLALVATTFSKGSARNTATAVFAAMTAIGS MAV_3702|M.avium_104 ATMVIARLSQGVGSAIASPTGLALVATTFPKGPARNFATAVFAAMTAVGS :: * *.:*.:: * :: : * : . . :.. .:. Mb3267c|M.bovis_AF2122/97 GLGPPIGGLLVEWAGWRWVLLVNVPLGIVAAIATKRMLVESRASGRRRMP Rv3239c|M.tuberculosis_H37Rv GLGPPIGGLLVEWAGWRWVLLVNVPLGIVAAIATKRMLVESRASGRRRMP MMAR_1306|M.marinum_M GLGPPIGGMLVDWASWRWVFLVNIPLGVVAVLATSRALVESRAAGRRRKP MUL_3590|M.ulcerans_Agy99 GLGPPVGGMLVEASSWRLVFLVNIPLGIVAVLVAGRVLTESRASGRRRVP TH_3965|M.thermoresistible__bu LIGPLAGGVLVDGLGWQWIFIVNVPIGIAGLVLGARLMP--RLPRQDQGF Mvan_4014|M.vanbaalenii_PYR-1 LAGPLIGGVLLAGLGWQWIFFVNAPIGAIGIALAVRLVP--NLPGRPVRI MAB_0945|M.abscessus_ATCC_1997 ALGPIVGGLLIQWVGWRAVFWINLPVCVLAFVLTAVFVPETKSATMRDID MSMEG_5670|M.smegmatis_MC2_155 ALGPLVGGALIEYVDWRAVFWINLPICALAILLTAIFVRESKSSTMRDVD Mflv_0301|M.gilvum_PYR-GCK AIGPFLGGALVEWN-WRAAFLINVPLAAFVIAVTLLRVPESRDPSASRRL MLBr_01562|M.leprae_Br4923 VMGLVVGGALTEVS-WRLAFLVNVPIGLVMIYLARTALHETHKER--MKL MAV_3702|M.avium_104 VMGLVVGGALTEVS-WRLAFLVNVPIGLVMMYLARTALRETNRER--MKL * ** * *: : :* *: : . Mb3267c|M.bovis_AF2122/97 DLRGALLLAVTLGLVTLGLVKGPDWGWLSVATVGSFLASVLTSVGFVHSS Rv3239c|M.tuberculosis_H37Rv DLRGALLLAVTLGLVTLGLVKGPDWGWLSVATVGSFLASVLTSVGFVHSS MMAR_1306|M.marinum_M DLRGATLLAGALGLLTLALVKGPDWGWVSVPTLAVFAASAITLVGFVLSS MUL_3590|M.ulcerans_Agy99 DLRGAMLLGVALGLMTLGLVKGPEWGWISTATIGSFVASSVALVAFVASS TH_3965|M.thermoresistible__bu DVLGMVLSAVGLFLIVFALQEAQTHRWAPWIWGTLAGGAGVMAMFVIWQS Mvan_4014|M.vanbaalenii_PYR-1 DVVGALLSGAGICLIVLGLQEGQHERWSWWIWVAIAGGLVSITAFLRWQT MAB_0945|M.abscessus_ATCC_1997 PVGQALAVLFLFGIVFALIEGPSLGWATPGLIVVLAVALAAFAVFLRYES MSMEG_5670|M.smegmatis_MC2_155 PVGQGLGVAFLFGVVFVLIEGPGMGWTDPRTLAVAATALVAFLAFLRYES Mflv_0301|M.gilvum_PYR-GCK DVGGAVLTVVGLGALTFGLTELGNRGASPAAVVSVGGGLVALVVFVLVEQ MLBr_01562|M.leprae_Br4923 DAAGAILATLACTAAVFAFSMGPEKGWISLTTIGSGLVALVAAIAFAVVE MAV_3702|M.avium_104 DATGAVLATLACTAAVFAFSMGPEKGWISLTTISSGVVALGAALAFVIVE : . Mb3267c|M.bovis_AF2122/97 RSHPAPLVEPALLRSRSFVAGNLLTLVAAAGFYCYGLTHVLYLNYVWHYS Rv3239c|M.tuberculosis_H37Rv RSHPAPLVEPALLRSRSFVAGNLLTLVAAAGFYCYGLTHVLYLNYVWHYS MMAR_1306|M.marinum_M MAAPVPLVEPAYLRSRPFVVGNVLTLVAAAGFYCYVLTHVLYLNYVWGYS MUL_3590|M.ulcerans_Agy99 RSHPTPLIDPAFLRVRSFVAGNLLTLVAAAGFYCYVLTHVLYLNYVWHYS TH_3965|M.thermoresistible__bu ANRRHPLVPLQIFADRNFMLANVGVATIGFVVTAMVLPAMFFAQAVCGLS Mvan_4014|M.vanbaalenii_PYR-1 VHADEPLIPMSLMSHRNFVLSTAGIALVSFVFVSFGVPLMIYLQEVCGLS MAB_0945|M.abscessus_ATCC_1997 R-RRHPFIDLRFFRSIPFASATLTAICACMAWSAFLFTMSLYLQGQRHFS MSMEG_5670|M.smegmatis_MC2_155 R-RHDPFIDLRFFRSVPFASATLVAVCAFAAYGAFLFMMSLYLQSERGYS Mflv_0301|M.gilvum_PYR-GCK R-SSHPLMSPKLFADRNFGVANAVTLLIYGALGAVFLLLVLQLQTVSGFS MLBr_01562|M.leprae_Br4923 RTAENPVVPFDLFRDRNRLVTFIAIFLAGGVIFSLTVSIGLYIQDILGYS MAV_3702|M.avium_104 RTAENPVVPFDLFRDRNRLVTFIAIFLAGGVMFTLTVCIGLYVQDILGYS *.: : . : : * Mb3267c|M.bovis_AF2122/97 LLKAGFAIAPAAVVAAVVAAALGRVAGRHGHRVIVLVGALVWAGSLVWYL Rv3239c|M.tuberculosis_H37Rv LLKAGFAIAPAAVVAAVVAAALGRVAGRHGHRVIVLVGALVWAGSLVWYL MMAR_1306|M.marinum_M LLKAGFAIAPAALVAAVVAALLGRVADRHGHRLIVTLGALVWAGSLFWYL MUL_3590|M.ulcerans_Agy99 LLKAGFAIAPAALIAAVVAAVLGRIADQRGHRLVVMAGAIIWAGSLVWYL TH_3965|M.thermoresistible__bu PTGSALLIAPMAVASGVLAPMAGRIVDRSHPTPVVGFGFSVVAVGLTWLA Mvan_4014|M.vanbaalenii_PYR-1 PVHAALLTAPMAVATAVLAPVVGRIVDRAHPRPVVGFGFGLLTAGLIWLA MAB_0945|M.abscessus_ATCC_1997 AMHTGLIYLPIAVGALVFSPISGRMVGRFGARPSLLAAGTLFLTASLLLT MSMEG_5670|M.smegmatis_MC2_155 AMFTGLIYLPIAIGALIFSPLSGRMVGRFGSRPSLVSAGVLITAATVMLA Mflv_0301|M.gilvum_PYR-GCK PVAAGTALLPFTIVMLLFSSRAGALSGRIGPRLPMTVGPVLAGLGLLLML MLBr_01562|M.leprae_Br4923 ALRAGIGFIPFVIAMGIGLGVSSQLVSRFSPRVLTIGGGWLLMVAMLYGW MAV_3702|M.avium_104 ALRAGVGFIPFVIAMGIGLGVSSQLVARFSPRVLTIAGGYLLVLAMLYGW :. * .: : . : : . : . Mb3267c|M.bovis_AF2122/97 QRVGSEPDFLRVWLPGQLLQGIGVGATLPVLSSAALAEVAKGGSYATSSA Rv3239c|M.tuberculosis_H37Rv QRVGSEPDFLRVWLPGQLLQGIGVGATLPVLSSAALAEVAKGGSYATSSA MMAR_1306|M.marinum_M QRVGTEPDFLRRWLPGQLLQGIGVGATLPVLSSAALTGVAKGGSYATTSA MUL_3590|M.ulcerans_Agy99 QRVGTEPNFLREWLPGQLLQGIGVGATLPVLGSAALAGLTKGGSYATASA TH_3965|M.thermoresistible__bu VEMAPTTPIWRLVLP-FVAVGVGMAFIWSPLATTATRQLP-LHLSGAGSG Mvan_4014|M.vanbaalenii_PYR-1 VEMTPDTPAWRLALP-LTMVGAAGAFTWEPLSAIATRGLT-SELAGAGSA MAB_0945|M.abscessus_ATCC_1997 RVSEATP-IWELLVT-FAIFGAGFAMVNAPITNAAVSGMP-LDRAGAASA MSMEG_5670|M.smegmatis_MC2_155 QMTATTP-VWLLLVI-FAVFGIGFALVNAPITTAAVSGMP-LDRAGAASA Mflv_0301|M.gilvum_PYR-GCK RIGEDASWVFDVAPA-ALVFGAGMVLVVAPLTATVLDAAP-EHMAGSASG MLBr_01562|M.leprae_Br4923 AFMNRGVPYFPNLLAPIVVGGIGIGMAVVPLTLSAIAGVG-FDRIGPVSA MAV_3702|M.avium_104 WCMHRGVPYFPNLVLPIVVGGIGIGMAVVPLTLSAIAGVG-FDQIGPVSA * . : . .. *. Mb3267c|M.bovis_AF2122/97 VVSTTRQLGAVLGVAVMVILIGKPEHGTAEEALRRGWAMAAICFIAVAVA Rv3239c|M.tuberculosis_H37Rv VVSTTRQLGAVLGVAVMVILIGKPEHGTAEEALRRGWAMAAICFIAVAVA MMAR_1306|M.marinum_M VVSTTRQLGAVIGVAALVILIGKPEHGAAADALRRGWAMAAICFVVVAIA MUL_3590|M.ulcerans_Agy99 VVSTTRQLGAVIGVALLVILIGKPAPGTGVEALRHGWVLAAVCFAAVAVL TH_3965|M.thermoresistible__bu VYNTTRQIGSVLGSAGMAAFLTGRLSAELPFGATAVPAGEQTRVLPEFLH Mvan_4014|M.vanbaalenii_PYR-1 VCNTARHVGAALSSAGIAALMAVLLGDEHAEEAGAR--HETLAPLVDSLK MAB_0945|M.abscessus_ATCC_1997 VTSTSRQVGVSIGVALCGSIG------------------TPALWFMCAGL MSMEG_5670|M.smegmatis_MC2_155 VASTSRQVGVSIGVALCGSVAGTALA--GTGVDFAA--ASRPLWLICTAL Mflv_0301|M.gilvum_PYR-GCK VNNAVARAGGLLAVAVLPGVAGISGNDYADPAAFSA--GFHTAVVISAVL MLBr_01562|M.leprae_Br4923 IALMLQSLGGPLVLAVIQAVITSRTLYLGGTTGPVKFMNDAQLRALDHGY MAV_3702|M.avium_104 VTLMLQSLGGPLVLAVIQAVITSRTLYLGGTTGPVKTMNDAQLQALDHGY : * : * . Mb3267c|M.bovis_AF2122/97 AAVLGRTNRNPVQMPAPEPAIA---PRLEPPIPQPAAAPIEH-WAAGDAD Rv3239c|M.tuberculosis_H37Rv AAVLGRTNRNPVQMPAPEPAIA---PRLEPPIPQPAAAPIEH-WAAGDAD MMAR_1306|M.marinum_M AVLLGRTNSKPGQELEPEPAAA---ARAAPTTTEPAAALIAN-RATDEAD MUL_3590|M.ulcerans_Agy99 AGFLGRTQQGADVAGAPESGVARAPARPQPVTPRPAAAPARPPQTTADGD TH_3965|M.thermoresistible__bu APYAA--------------------------------------------- Mvan_4014|M.vanbaalenii_PYR-1 DPFAG--------------------------------------------- MAB_0945|M.abscessus_ATCC_1997 GLLIA--------------------------------------------- MSMEG_5670|M.smegmatis_MC2_155 GVVIV--------------------------------------------- Mflv_0301|M.gilvum_PYR-GCK MVAAA--------------------------------------------- MLBr_01562|M.leprae_Br4923 TYGLLW-------------------------------------------- MAV_3702|M.avium_104 TYGLLW-------------------------------------------- Mb3267c|M.bovis_AF2122/97 PLGNLPLFAGLDAATLAQLGEHVEDVELEAGCYLFHEGDPSDSLYVIRTG Rv3239c|M.tuberculosis_H37Rv PLGNLPLFAGLDAATLAQLGEHVEDVELEAGCYLFHEGDPSDSLYVIRTG MMAR_1306|M.marinum_M LLGNLPLFAGLDAAALAELADRVEEVELQAGSYLFLAGDASDSLYVIRRG MUL_3590|M.ulcerans_Agy99 LLRQLPLFAGLPAATMAELRHHTDEIELQAGSYLFHEVDPSDALYVVRSG TH_3965|M.thermoresistible__bu ------------------------------------------AMAQSMLL Mvan_4014|M.vanbaalenii_PYR-1 ------------------------------------------AMAQSMLL MAB_0945|M.abscessus_ATCC_1997 ------------------------------------------TLGIVSTS MSMEG_5670|M.smegmatis_MC2_155 ------------------------------------------AIGIVSTS Mflv_0301|M.gilvum_PYR-GCK ------------------------------------------VLAAIGIR MLBr_01562|M.leprae_Br4923 ------------------------------------------VAGAVVIV MAV_3702|M.avium_104 ------------------------------------------VAGAAVIV Mb3267c|M.bovis_AF2122/97 RVQVLQDSIVLKELGRGEVLGELGLLIDAPRSATVRALRDTKLVRLTKAQ Rv3239c|M.tuberculosis_H37Rv RVQVLQDSIVLKELGRGEVLGELGLLIDAPRSATVRALRDTKLVRLTKAQ MMAR_1306|M.marinum_M RVQVLHGDIVIKELGRGEVLGELGLLIDAPRSASVRALRDSRLVRLTKAQ MUL_3590|M.ulcerans_Agy99 RLRVVQRDLVLRELGRGEVVGELGLLIDAPRSASVQAMRDFVLIRLSKAQ TH_3965|M.thermoresistible__bu PAFVALFGVLAAIFLAGIVLSTPQPDADAQYLDEHDDYLVIELARPDPNP Mvan_4014|M.vanbaalenii_PYR-1 PAAAAAMGVLTALFLVG---------GDAT-------------ARAAP-- MAB_0945|M.abscessus_ATCC_1997 PAAVRSAQRLAPLI-EGTTAREMSRVG----------------------- MSMEG_5670|M.smegmatis_MC2_155 PWALRSAERLAPLIGQHHRPAEVAHAR----------------------- Mflv_0301|M.gilvum_PYR-GCK RAPARSDERMAVENCTHCAITGLPAHPAAETR------------------ MLBr_01562|M.leprae_Br4923 GVAALFIGYTPEQVAYAQEVKEAVDAGEL--------------------- MAV_3702|M.avium_104 GAAALFIGYTPEQVAHAQEVKEAMDAGEL--------------------- Mb3267c|M.bovis_AF2122/97 FDEIADHGALAALVKVLATRLREAPPPATDS-TSPEVVVSVIGVSGDAPV Rv3239c|M.tuberculosis_H37Rv FDEIADHGALAALVKVLATRLREAPPPATDS-TSPEVVVSVIGVSGDAPV MMAR_1306|M.marinum_M FDQIANRGVLAALVRVLATRLREAPPPAVHT-TSPGVVVSVVGVGADAPV MUL_3590|M.ulcerans_Agy99 FNRIADRGVLAALVGTLATRLHTAPPPTVDRPASPEAVIAVIGLGAAVPV TH_3965|M.thermoresistible__bu RTDIAVTAVIPALRPTLRPTLRPSLGPPGGPVVQPNNTAALR-------- Mvan_4014|M.vanbaalenii_PYR-1 ----------------------LSLRPWGDASVSS--------------- MAB_0945|M.abscessus_ATCC_1997 -------------------------------------------------- MSMEG_5670|M.smegmatis_MC2_155 -------------------------------------------------- Mflv_0301|M.gilvum_PYR-GCK -------------------------------------------------- MLBr_01562|M.leprae_Br4923 -------------------------------------------------- MAV_3702|M.avium_104 -------------------------------------------------- Mb3267c|M.bovis_AF2122/97 PAVAAGLLTALSARLRAVDPGRVDRDGLDRAERVADKVVLHAAVEDAGWR Rv3239c|M.tuberculosis_H37Rv PAVAAGLLTALSARLRAVDPGRVDRDGLDRAERVADKVVLHAAVEDAGWR MMAR_1306|M.marinum_M QSVAAGLLTALSKQLRVVDPGRVDIDGLDRAERGADKVLLHAGAQDADWR MUL_3590|M.ulcerans_Agy99 RPVALALLNALSARVTAVDPGRVDRAGLERAEASADKVVLDASANDTGWR TH_3965|M.thermoresistible__bu -------------------------------------------------- Mvan_4014|M.vanbaalenii_PYR-1 -------------------------------------------------- MAB_0945|M.abscessus_ATCC_1997 -------------------------------------------------- MSMEG_5670|M.smegmatis_MC2_155 -------------------------------------------------- Mflv_0301|M.gilvum_PYR-GCK -------------------------------------------------- MLBr_01562|M.leprae_Br4923 -------------------------------------------------- MAV_3702|M.avium_104 -------------------------------------------------- Mb3267c|M.bovis_AF2122/97 DFCLRVADRIVLVAGDPNPQAARLPARARGADLVLAGPAASREHRRQWEE Rv3239c|M.tuberculosis_H37Rv DFCLRVADRIVLVAGDPNPQAARLPARARGADLVLAGPAASREHRRQWEE MMAR_1306|M.marinum_M DFCLRVADRIVLVTGDPDPGAAALPARAQGADLVLAGPTASREQRRSWEE MUL_3590|M.ulcerans_Agy99 DFCLRAADRIVLVSEGPAPRDTQLPARAVGADLVLIGAPASQEDRSRWEE TH_3965|M.thermoresistible__bu -------------------------------------------------- Mvan_4014|M.vanbaalenii_PYR-1 -------------------------------------------------- MAB_0945|M.abscessus_ATCC_1997 -------------------------------------------------- MSMEG_5670|M.smegmatis_MC2_155 -------------------------------------------------- Mflv_0301|M.gilvum_PYR-GCK -------------------------------------------------- MLBr_01562|M.leprae_Br4923 -------------------------------------------------- MAV_3702|M.avium_104 -------------------------------------------------- Mb3267c|M.bovis_AF2122/97 LITPRSVHVVHYRRILENVRPLAARIAGRSIGLVLGGGGARGFAHLGVLD Rv3239c|M.tuberculosis_H37Rv LITPRSVHVVHYRRILENVRPLAARIAGRSIGLVLGGGGARGFAHLGVLD MMAR_1306|M.marinum_M LITPRSVHAVHYRRVVQDLRPLAARLAGRSIGLVLGGGGARGFAHLGILE MUL_3590|M.ulcerans_Agy99 LIPPRSVHSVSYRSLKDDVRPLAARITGGSIGLVLGGGGARAFAHLGVLD TH_3965|M.thermoresistible__bu -------------------------------------------------- Mvan_4014|M.vanbaalenii_PYR-1 -------------------------------------------------- MAB_0945|M.abscessus_ATCC_1997 -------------------------------------------------- MSMEG_5670|M.smegmatis_MC2_155 -------------------------------------------------- Mflv_0301|M.gilvum_PYR-GCK -------------------------------------------------- MLBr_01562|M.leprae_Br4923 -------------------------------------------------- MAV_3702|M.avium_104 -------------------------------------------------- Mb3267c|M.bovis_AF2122/97 ELERVGVTIDRFAGTSMGAVIAVFGACGMDAATADAYAYEYFIRHNPLSD Rv3239c|M.tuberculosis_H37Rv ELERVGVTIDRFAGTSMGAVIAVFGACGMDAATADAYAYEYFIRHNPLSD MMAR_1306|M.marinum_M ELEQAGVAIDRFAGTSMGAVIASLGASGLDAATADAYAYEYFIRNNPLRD MUL_3590|M.ulcerans_Agy99 ELEAAGIVVDRFAGTSMGAVIAALAASGLDAAGVDAHVFEYLVRHNPLGD TH_3965|M.thermoresistible__bu -------------------------------------------------- Mvan_4014|M.vanbaalenii_PYR-1 -------------------------------------------------- MAB_0945|M.abscessus_ATCC_1997 -------------------------------------------------- MSMEG_5670|M.smegmatis_MC2_155 -------------------------------------------------- Mflv_0301|M.gilvum_PYR-GCK -------------------------------------------------- MLBr_01562|M.leprae_Br4923 -------------------------------------------------- MAV_3702|M.avium_104 -------------------------------------------------- Mb3267c|M.bovis_AF2122/97 YAFPVRGLVHGRRTLTLLEAAFGDRLVEELPKEFRCVSVDLLARRPVVHR Rv3239c|M.tuberculosis_H37Rv YAFPVRGLVRGRRTLTLLEAAFGDRLVEELPKEFRCVSVDLLARRPVVHR MMAR_1306|M.marinum_M YAVPIKGLVRGRRTLTLLEAAFGDRLVEELPKEFRCVSVDLIARQPVVHR MUL_3590|M.ulcerans_Agy99 YTLPSKGLVRGRRTMGLLREAYSGRMVEELPKEFRCVSVDLLARQAVVHR TH_3965|M.thermoresistible__bu -------------------------------------------------- Mvan_4014|M.vanbaalenii_PYR-1 -------------------------------------------------- MAB_0945|M.abscessus_ATCC_1997 -------------------------------------------------- MSMEG_5670|M.smegmatis_MC2_155 -------------------------------------------------- Mflv_0301|M.gilvum_PYR-GCK -------------------------------------------------- MLBr_01562|M.leprae_Br4923 -------------------------------------------------- MAV_3702|M.avium_104 -------------------------------------------------- Mb3267c|M.bovis_AF2122/97 RGRLVDVIGCSLRLPGIYPPQVYNGRLHVDGGVLDNLPVSTRASPDGPLI Rv3239c|M.tuberculosis_H37Rv RGRLVDVIGCSLRLPGIYPPQVYNGRLHVDGGVLDNLPVSTRASPDGPLI MMAR_1306|M.marinum_M RGRLVDVVGCSLRLPGIYPPQVYQGRLHVDGGVLDNLPVSTLATSDGPLI MUL_3590|M.ulcerans_Agy99 RGPVAEVVGCSLRVPGLYPPQIYNGQLHVDGGVLNNLPVTALTRAEGPMI TH_3965|M.thermoresistible__bu -------------------------------------------------- Mvan_4014|M.vanbaalenii_PYR-1 -------------------------------------------------- MAB_0945|M.abscessus_ATCC_1997 -------------------------------------------------- MSMEG_5670|M.smegmatis_MC2_155 -------------------------------------------------- Mflv_0301|M.gilvum_PYR-GCK -------------------------------------------------- MLBr_01562|M.leprae_Br4923 -------------------------------------------------- MAV_3702|M.avium_104 -------------------------------------------------- Mb3267c|M.bovis_AF2122/97 AVSIGLGGGG-PGSARQDGSPKVPGIGDTLMRTMTIGSQRGADAALSLAQ Rv3239c|M.tuberculosis_H37Rv AVSIGLGGGG-PGSARQDGSPKVPGIGDTLMRTMTIGSQRGADAALSLAQ MMAR_1306|M.marinum_M AVSLASGEVP-GAPLQPDGPPRVPGIGDTLIRTMTIGSQRGADVALGLAQ MUL_3590|M.ulcerans_Agy99 AVSVGFGGNPSGGQPRRSGPIQVPGIGDTLMRTMMMGSRTVADAAQAEAL TH_3965|M.thermoresistible__bu -------------------------------------------------- Mvan_4014|M.vanbaalenii_PYR-1 -------------------------------------------------- MAB_0945|M.abscessus_ATCC_1997 -------------------------------------------------- MSMEG_5670|M.smegmatis_MC2_155 -------------------------------------------------- Mflv_0301|M.gilvum_PYR-GCK -------------------------------------------------- MLBr_01562|M.leprae_Br4923 -------------------------------------------------- MAV_3702|M.avium_104 -------------------------------------------------- Mb3267c|M.bovis_AF2122/97 VVIRPDTGAVGLLEFHQIDAAREAGRVAAREAMPHIMALLNR-------- Rv3239c|M.tuberculosis_H37Rv VVIRPDTGAVGLLEFHQIDAAREAGRVAAREAMPHIMALLNR-------- MMAR_1306|M.marinum_M VVIRPDTSAVGLLEFHQIDAAREAGRAAARESMPQIMALLNQRR------ MUL_3590|M.ulcerans_Agy99 VVIRPDTRAVGLLEFHQIDAAREAGRAAARAALPQIIPLLRSGPAGQTTG TH_3965|M.thermoresistible__bu -------------------------------------------------- Mvan_4014|M.vanbaalenii_PYR-1 -------------------------------------------------- MAB_0945|M.abscessus_ATCC_1997 -------------------------------------------------- MSMEG_5670|M.smegmatis_MC2_155 -------------------------------------------------- Mflv_0301|M.gilvum_PYR-GCK -------------------------------------------------- MLBr_01562|M.leprae_Br4923 -------------------------------------------------- MAV_3702|M.avium_104 -------------------------------------------------- Mb3267c|M.bovis_AF2122/97 ------------------ Rv3239c|M.tuberculosis_H37Rv ------------------ MMAR_1306|M.marinum_M ------------------ MUL_3590|M.ulcerans_Agy99 RAIDRSARALRTDARRPA TH_3965|M.thermoresistible__bu ------------------ Mvan_4014|M.vanbaalenii_PYR-1 ------------------ MAB_0945|M.abscessus_ATCC_1997 ------------------ MSMEG_5670|M.smegmatis_MC2_155 ------------------ Mflv_0301|M.gilvum_PYR-GCK ------------------ MLBr_01562|M.leprae_Br4923 ------------------ MAV_3702|M.avium_104 ------------------