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M. vanbaalenii PYR-1 Mvan_4014 (-)

annotation: EmrB/QacA family drug resistance transporter
coordinates: 4293940 - 4295454
length: 504

SQHRPHDAIAAEPTDDHPFRALWVMMVGFFLIVVDSTVIAVANPVLKNDFDVEYHSVIWVTSGYLLAFAA
FLLIGGRLGDRFGSKPVYLVGLTLFAAASVWCGLSTSVGMLIAARVAQGVGAALLTPQIMSTITRTFPPQ
RHGMAMSVWGATAGVGMLAGPLIGGVLLAGLGWQWIFFVNAPIGAIGIALAVRLVPNLPGRPVRIDVVGA
LLSGAGICLIVLGLQEGQHERWSWWIWVAIAGGLVSITAFLRWQTVHADEPLIPMSLMSHRNFVLSTAGI
ALVSFVFVSFGVPLMIYLQEVCGLSPVHAALLTAPMAVATAVLAPVVGRIVDRAHPRPVVGFGFGLLTAG
LIWLAVEMTPDTPAWRLALPLTMVGAAGAFTWEPLSAIATRGLTSELAGAGSAVCNTARHVGAALSSAGI
AALMAVLLGDEHAEEAGARHETLAPLVDSLKDPFAGAMAQSMLLPAAAAAMGVLTALFLVGGDATARAAP
LSLRPWGDASVSS*
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. vanbaalenii PYR-1Mvan_4014--100% (504)EmrB/QacA family drug resistance transporter
M. vanbaalenii PYR-1Mvan_4474-e-15657.86% (477) EmrB/QacA family drug resistance transporter
M. vanbaalenii PYR-1Mvan_0523-3e-5430.49% (410) EmrB/QacA family drug resistance transporter

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb1282-1e-14151.23% (488) drug-transport integral membrane protein
M. gilvum PYR-GCKMflv_2221-1e-15557.50% (480) EmrB/QacA family drug resistance transporter
M. tuberculosis H37RvRv1250-1e-14051.02% (488) drug-transport integral membrane protein
M. leprae Br4923MLBr_01562-3e-4328.39% (398) putative transmembrane efflux protein
M. abscessus ATCC 19977MAB_1396-1e-12847.08% (480) EmrB/QacA family drug resistance transporter
M. marinum MMMAR_4192-1e-13850.21% (480) drug-transport integral membrane protein
M. avium 104MAV_1387-1e-14955.27% (474) drug transporter
M. smegmatis MC2 155MSMEG_5046-1e-15054.91% (479) drug transporter
M. thermoresistible (build 8)TH_3965-1e-14653.99% (476) PUTATIVE drug transporter
M. ulcerans Agy99MUL_0911-1e-5130.85% (470) integral membrane transport protein

CLUSTAL 2.0.9 multiple sequence alignment


Mb1282|M.bovis_AF2122/97            -------------------------MTTAIRRAAG-----------SSYF
Rv1250|M.tuberculosis_H37Rv         -------------------------MTTAIRRAAG-----------SSYF
MMAR_4192|M.marinum_M               -------------------------MTAVTSRVLD-----------NGYS
MAV_1387|M.avium_104                --------------------------------------------------
Mflv_2221|M.gilvum_PYR-GCK          ------------------------MFDTVTSRAA--------------GT
MSMEG_5046|M.smegmatis_MC2_155      ------------------------MPSSLNARIAGLLPSRVGALRPQDGT
TH_3965|M.thermoresistible__bu      -------------------------VTSVDAGRS-TMSEVFTAYAPRSAA
MAB_1396|M.abscessus_ATCC_1997      ---------------------------------------------MRPEY
Mvan_4014|M.vanbaalenii_PYR-1       -------------------------MSQHRPHDAIA---------AEPTD
MUL_0911|M.ulcerans_Agy99           ------------------------------------------MRIQPVFR
MLBr_01562|M.leprae_Br4923          MVTLYDHERAVHNWTAARSDRPAPSRLTQQVEPASERTSKYPTLLPSGRF
                                                                                      

Mb1282|M.bovis_AF2122/97            RNPWPALWAMMVG--FFMIMLDSTVVAIANPTIMAQLRIGYATVVWVTSA
Rv1250|M.tuberculosis_H37Rv         RNPWPALWAMMVG--FFMIMLDSTVVAIANPTIMAQLRIGYATVVWVTSA
MMAR_4192|M.marinum_M               GNPWNALSAMMIG--FFMIMLDSTIVSIANPTIMAELHIGYADVVWVTSA
MAV_1387|M.avium_104                ---------MMIG--FFMIMVDSTIVAIANPTIMADLHIGYDTVVWVTSA
Mflv_2221|M.gilvum_PYR-GCK          TNPWPALWALLIG--FFMILVDATIVAVANPAIMASLNAGYDAVIWVTSA
MSMEG_5046|M.smegmatis_MC2_155      GNPWNALWAMMFG--FFMILVDATIVSVANPTIMVELGADYDGVIWVTSA
TH_3965|M.thermoresistible__bu      ANPWHALWAMLIG--FFMILVDATIVPVANLEIMADLGADYTAVIWVTSA
MAB_1396|M.abscessus_ATCC_1997      PRPWITLWVVLFG--LFMILLDSTIVSVANPAIKAGFGADYSSTVWVTSA
Mvan_4014|M.vanbaalenii_PYR-1       DHPFRALWVMMVG--FFLIVVDSTVIAVANPVLKNDFDVEYHSVIWVTSG
MUL_0911|M.ulcerans_Agy99           DHPILALAVICLS--VFVISVDATIVNVALPTLSRELGADTAQLQWIVDA
MLBr_01562|M.leprae_Br4923          PSGRFIAAVIVIGGMQLLATMDSTVAIVALPKIQNELSLSDAGRSWGITA
                                             : ..   ::  :*:*:  :*   :   :        *   .

Mb1282|M.bovis_AF2122/97            YLLAYAVPMLVAGRLGDRFGPKNLYLIGLGVFTVASLGCGLSSGAGMLIA
Rv1250|M.tuberculosis_H37Rv         YLLAYAVPMLVAGRLGDRFGPKNLYLIGLGVFTVASLGCGLSSGAGMLIA
MMAR_4192|M.marinum_M               YLLGYAVVLLVAGRLGDRFGPKNLYLIGLSVFTAASMWCGLAGTAAMLIA
MAV_1387|M.avium_104                YLLGYAVVLLVAGRLGDRFGTKNLYLIGLAVFTVASVWCGLAGSAAMLIA
Mflv_2221|M.gilvum_PYR-GCK          YLLAYAVPLLVSGRLGDRYGPKNVYMVGLTVFTVASLWCGLSDSIGMLIA
MSMEG_5046|M.smegmatis_MC2_155      YLLAYAVPLLVTGRLGDMYGPKNLYLLGLGVFTAASLWCGLAGSIEMLIA
TH_3965|M.thermoresistible__bu      YLLAYAVPLLIAGRLGDRFGPRTMYLIGLAIFTAASLWCGLAGTIGMLIA
MAB_1396|M.abscessus_ATCC_1997      YLLGYAVPLLITGRLGDQFGPRSMYLSGLAVFTAASLWCGLAGSIGWLIA
Mvan_4014|M.vanbaalenii_PYR-1       YLLAFAAFLLIGGRLGDRFGSKPVYLVGLTLFAAASVWCGLSTSVGMLIA
MUL_0911|M.ulcerans_Agy99           YTLVMSGLLLSAGSLSDRYGRRGWLSAGLILFALTSALAAQVNSADTLVA
MLBr_01562|M.leprae_Br4923          YVLTFGGLMLLGGRLGDTIGRKRTFIVGVALFTISSVLCAVAWDEVTLVI
                                    * *  .  :*  * *.*  * :     *: :*: :*  ..       *: 

Mb1282|M.bovis_AF2122/97            ARVVQGVGAGLLTPQTLSTITRIFPAHR-RGVALGAWGTVASVASLVGPL
Rv1250|M.tuberculosis_H37Rv         ARVVQGVGAGLLTPQTLSTITRIFPAHR-RGVALGAWGTVASVASLVGPL
MMAR_4192|M.marinum_M               ARTVQGIGAGLLTPQTLSTITRIFPATR-RGAALSLWGAAAGVASLVGPL
MAV_1387|M.avium_104                ARVVQGVGAGVMTPQTLSTITRIFPAER-RGVAVSVWSATAGAASLAGPL
Mflv_2221|M.gilvum_PYR-GCK          ARVVQGVGAALLTPQTMTVITRTFPAHR-RGVAMSVWGATAGVATLVGPL
MSMEG_5046|M.smegmatis_MC2_155      ARVVQGIGAALLTPQTLSAITRIFPANR-RGVAMSVWGATAGVATLVGPL
TH_3965|M.thermoresistible__bu      ARVLQGLGAALLTPQTLSMITRIFPADR-RGVPMGVWGATAGVATLIGPL
MAB_1396|M.abscessus_ATCC_1997      ARVVQGIGAAMLTPQTLTVVQRVFPPER-RGTAMGVWGAVAGIATLVGPV
Mvan_4014|M.vanbaalenii_PYR-1       ARVAQGVGAALLTPQIMSTITRTFPPQR-HGMAMSVWGATAGVGMLAGPL
MUL_0911|M.ulcerans_Agy99           ARAAMGVGAAVIFPTTLGLITNIFTDPVPRAKAIGLWTAMVGVGVAVGPI
MLBr_01562|M.leprae_Br4923          ARLLQGIGSAIASPTGLALVATTFSKGSARNTATAVFAAMTAIGSVMGLV
                                    **   *:*:.:  *  :  :   *.    :  . . : : .. .   * :

Mb1282|M.bovis_AF2122/97            AGGALVDSMGWEWIFFVNVPVGVIGLILAAYLIPALP-HHPHRFDWFGVG
Rv1250|M.tuberculosis_H37Rv         AGGALVDSMGWEWIFFVNVPVGVIGLILAAYLIPALP-HHPHRFDWFGVG
MMAR_4192|M.marinum_M               IGGVLVSGLGWEWIFFVNIPIGLAGLVVAYLLVPDLP-VHAQRFDLIGVG
MAV_1387|M.avium_104                AGGVLVDGLGWQWIFFVNVPIGVLGLVLAYWLVPVLP-TQSHRFDLVGVG
Mflv_2221|M.gilvum_PYR-GCK          AGGVLVDSLGWQWIFIVNVPVGIVGLVMALRLVPALPNPVRQGFDVPGVV
MSMEG_5046|M.smegmatis_MC2_155      AGGVLVGGLGWQWIFFVNVPVGIVGIALAVWLVPTLP-TTRHHFDIPGIV
TH_3965|M.thermoresistible__bu      AGGVLVDGLGWQWIFIVNVPIGIAGLVLGARLMPRLP-RQDQGFDVLGMV
MAB_1396|M.abscessus_ATCC_1997      AGGLLVDGWGWQWIFYVNVPVGVLGIILGAIYIPRMP-THRHRLDLLGMA
Mvan_4014|M.vanbaalenii_PYR-1       IGGVLLAGLGWQWIFFVNAPIGAIGIALAVRLVPNLP-GRPVRIDVVGAL
MUL_0911|M.ulcerans_Agy99           TGGWLLEHFSWGSIFLVNVPIAVAAMAGAILFVPTSRDPAAPRVDVPGLM
MLBr_01562|M.leprae_Br4923          VGGALTEVS-WRLAFLVNVPIGLVMIYLARTALHETH-KERMKLDAAGAI
                                     ** *     *   * ** *:.   :  .   :          .*  *  

Mb1282|M.bovis_AF2122/97            LSGAGMFLIVFGLQQGQSANWQP-WIWAVIVGGIGFMSLFVYWQARNARE
Rv1250|M.tuberculosis_H37Rv         LSGAGMFLIVFGLQQGQSANWQP-WIWAVIVGGIGFMSLFVYWQARNARE
MMAR_4192|M.marinum_M               LSGAGMFLLVFGLQEGQAADWAP-WIWAVLVAGVGFMAMFVYWQALNHRA
MAV_1387|M.avium_104                LSGVGMLLIVFGLQQGQAAHWQP-WIWALIVAGVGFVTVFVFWQSVNVRE
Mflv_2221|M.gilvum_PYR-GCK          LSGVGLFLIVFALQEGQSHGWAL-WIWATVLAGVAVMAAFVYWQSINTAG
MSMEG_5046|M.smegmatis_MC2_155      LSAVGMFLIVFALQEGQSKDWAP-WVWGTATLGVGVMAAFFFWQSVNTRE
TH_3965|M.thermoresistible__bu      LSAVGLFLIVFALQEAQTHRWAP-WIWGTLAGGAGVMAMFVIWQSANRRH
MAB_1396|M.abscessus_ATCC_1997      LSAVGMFAFVFALQEGESFQWAP-GVWAMMAAGLVVLGVFVWWQSANRGE
Mvan_4014|M.vanbaalenii_PYR-1       LSGAGICLIVLGLQEGQHERWSW-WIWVAIAGGLVSITAFLRWQTVHADE
MUL_0911|M.ulcerans_Agy99           LSAVGITALVYTIIEAPNWGWTSTRASGGFIAAAIVLVGFALWERRSS-H
MLBr_01562|M.leprae_Br4923          LATLACTAAVFAFSMGPEKGWISLTTIGSGLVALVAAIAFAVVE-RTAEN
                                    *:  .    *  :  .    *           .      *   :      

Mb1282|M.bovis_AF2122/97            PLIPLEVFNDRNFSLSNLGIAIIAFAGTGMMLPVTFYAQAVCGLSPTHTA
Rv1250|M.tuberculosis_H37Rv         PLIPLEVFNDRNFSLSNLRIAIIAFAGTGMMLPVTFYAQAVCGLSPTHTA
MMAR_4192|M.marinum_M               PLISLAIFRDWEFSLCNIGVGITAFATTAPMLPLTFYAQSVCGLSPARAA
MAV_1387|M.avium_104                PLIPLVIFSDRDFSLCNIGVAIISFAATAMMLPLTFYAQAVCGLSPTRSA
Mflv_2221|M.gilvum_PYR-GCK          ALIPLVIFRDRNFSMSNLGVATIGFVATGMILPLMFFAQAVCGLTPTRAA
MSMEG_5046|M.smegmatis_MC2_155      PLIPLRVFADRDFTLANIGVAVIGFAVTAMILPLMFYLQTVCGLSPIRSA
TH_3965|M.thermoresistible__bu      PLVPLQIFADRNFMLANVGVATIGFVVTAMVLPAMFFAQAVCGLSPTGSA
MAB_1396|M.abscessus_ATCC_1997      PLIPLRLFADRNFSLAGVGIASMSFCVISTGLPMMFYTQLALGFSPTKAA
Mvan_4014|M.vanbaalenii_PYR-1       PLIPMSLMSHRNFVLSTAGIALVSFVFVSFGVPLMIYLQEVCGLSPVHAA
MUL_0911|M.ulcerans_Agy99           PMLDVSVFANRRFSGGSLAVTAGFLTLFGFIFVITQYFQFIKDYTALQTG
MLBr_01562|M.leprae_Br4923          PVVPFDLFRDRNRLVTFIAIFLAGGVIFSLTVSIGLYIQDILGYSALRAG
                                    .:: . :: .         :        .  .    : *   . :.  :.

Mb1282|M.bovis_AF2122/97            VLFAPTAIVGGVLAPFVGMIIDRSHPLCVLGFGFSVLAIAMTWLLCEMAP
Rv1250|M.tuberculosis_H37Rv         VLFAPTAIVGGVLAPFVGMIIDRSHPLCVLGFGFSVLAIAMTWLLCEMAP
MMAR_4192|M.marinum_M               VLIAPVALASGVLAPVVGMLVDRSHPLPVLGFGFSALAISMTWLSIEMVP
MAV_1387|M.avium_104                LLIAPMAIANGVFAPFVGKIVDRYHPRPVLGFGFSLLAIALTWLTFEMSP
Mflv_2221|M.gilvum_PYR-GCK          LLTAPMAVATGVLAPFVGKLVDRAHPRSVVGFGFSLMAIGVTWLSIEMTP
MSMEG_5046|M.smegmatis_MC2_155      LVTAPTAIASGVLAPFVGRIVDRVHPMPVIGFGFSAMAIGLTWLSIEMAP
TH_3965|M.thermoresistible__bu      LLIAPMAVASGVLAPMAGRIVDRSHPTPVVGFGFSVVAVGLTWLAVEMAP
MAB_1396|M.abscessus_ATCC_1997      LTQAPTAIVSGILAPLAGWLVDRVRPSILIGGGIALMIASTLWWTLLMRP
Mvan_4014|M.vanbaalenii_PYR-1       LLTAPMAVATAVLAPVVGRIVDRAHPRPVVGFGFGLLTAGLIWLAVEMTP
MUL_0911|M.ulcerans_Agy99           VRLLPVAFSIALAAILGPRLVERVGTTAVVAAGLAVFAAALAWASTADA-
MLBr_01562|M.leprae_Br4923          IGFIPFVIAMGIGLGVSSQLVSRFSPRVLTIGGGWLLMVAMLYGWAFMNR
                                    :   * ..  .:   .   ::.*  .  :   *   .  .  :       

Mb1282|M.bovis_AF2122/97            GTPIWR-LVLPFIALGVAGAFVWSPLTVTATRNLRPHLAGASSGVFNAVR
Rv1250|M.tuberculosis_H37Rv         GTPIWR-LVLPFIALGVAGAFVWSPLTVTATRNLRPHLAGASSGVFNAVR
MMAR_4192|M.marinum_M               ETPVWR-LVLPFAAMGAGMAFVWSPLAATATRNLPAHLAGAGSGVYNATR
MAV_1387|M.avium_104                ATPIWR-LVLPFFAMGVGMAFVWSPLTATATRNLSAQLAGAGSAVYNSVR
Mflv_2221|M.gilvum_PYR-GCK          TTPIWR-LLLPLTAMGAAMAFIWSPLAATATRNLPPHLAGAGSGVYNTTR
MSMEG_5046|M.smegmatis_MC2_155      TTPIWR-LLLPQLLMGIGMAFIWSPLAATATRHLPPDLAGAGSGVYNTTR
TH_3965|M.thermoresistible__bu      TTPIWR-LVLPFVAVGVGMAFIWSPLATTATRQLPLHLSGAGSGVYNTTR
MAB_1396|M.abscessus_ATCC_1997      ETQMWQ-LMLPAAGIGAAMACIWGPLATTATRNLPPSVAGAGSGVYNTLR
Mvan_4014|M.vanbaalenii_PYR-1       DTPAWR-LALPLTMVGAAGAFTWEPLSAIATRGLTSELAGAGSAVCNTAR
MUL_0911|M.ulcerans_Agy99           TTPYTQ-ITLQMLLLGGGLGLTTAPATEAIMGSLPADRAGVGSAVNDTTR
MLBr_01562|M.leprae_Br4923          GVPYFPNLLAPIVVGGIGIGMAVVPLTLSAIAGVGFDRIGPVSAIALMLQ
                                     .     :       * . .    * :      :     *  *.:    :

Mb1282|M.bovis_AF2122/97            QLGAVLGSASMAAFMTSRIAAEMPGGVDALTGPAGQDATVLQLPEFVREP
Rv1250|M.tuberculosis_H37Rv         QLGAVLGSASMAAFMTSRIAAEMPGGVDALTGPAGQDATVLQLPEFVREP
MMAR_4192|M.marinum_M               QLGAVLGSASMAAFMTWRITAEMPPGFDADRGFSGGDG-GLQLPEVVRTP
MAV_1387|M.avium_104                QLGAVLGSAGMAAFMTWRIGAEMPG----QPGGGGEDSAGPVLPEFLRGP
Mflv_2221|M.gilvum_PYR-GCK          QVGSVLGSAGMAALMSSELSTKIPG-ADAVPQSE---GEVAALPQFLREP
MSMEG_5046|M.smegmatis_MC2_155      QVGSVLGSAGIAAFMTWRITDEVPGMQDAAPAGES-GGAVEQLPEFLREP
TH_3965|M.thermoresistible__bu      QIGSVLGSAGMAAFLTGRLSAELPFGATAVPAGE----QTRVLPEFLHAP
MAB_1396|M.abscessus_ATCC_1997      QVGGVVGSSAMGALMTARLTATMPAMPPGSGSTP-----EAALPPGLRAP
Mvan_4014|M.vanbaalenii_PYR-1       HVGAALSSAGIAALMAVLLGDEHAEEAGARHETL------APLVDSLKDP
MUL_0911|M.ulcerans_Agy99           ELGGTLGVAIAGSVFASVYSGQLGSASALATLPS-------DVRSAMKGS
MLBr_01562|M.leprae_Br4923          SLGGPLVLAVIQAVITSR-TLYLGGTTGPVKFMN----------DAQLRA
                                     :*. :  :   :.::                                 .

Mb1282|M.bovis_AF2122/97            FAAAMSQSMLLPA--FVALFGIVAALFLVDFTGAAVAKEPLP--------
Rv1250|M.tuberculosis_H37Rv         FAAAMSQSMLLPA--FVALFGIVAALFLVDFTGAAVAKEPLP--------
MMAR_4192|M.marinum_M               FSAAMSQSMLLPA--FIAVFGIIAALFLVRSRTAPVRAHDRASHADDDHV
MAV_1387|M.avium_104                FAAAMSQSVLLPA--FIALFGIVAALFLVGFRPWAHRDGGTDAFGPDD--
Mflv_2221|M.gilvum_PYR-GCK          FALAMSQSMLLPA--FVALFGVIAALFLFDLLGDRDAAAPPAPDVEPLE-
MSMEG_5046|M.smegmatis_MC2_155      FSAAMSQAMLLPA--FIALFGVVAALFLLGFGSNRAAGHP----------
TH_3965|M.thermoresistible__bu      YAAAMAQSMLLPA--FVALFGVLAAIFLAGIVLS----TP----------
MAB_1396|M.abscessus_ATCC_1997      FSAAMAQSMLLGI--AALALGLVAALFMR---------------------
Mvan_4014|M.vanbaalenii_PYR-1       FAGAMAQSMLLPA--AAAAMGVLTALFLVG--------------------
MUL_0911|M.ulcerans_Agy99           MAVAHKVIDQLPAGPAAGVRDAVNHAFLDGLQVATLVCAG----------
MLBr_01562|M.leprae_Br4923          LDHGYTYGLLWVAG--AVVIVGVAALFIG---------------------
                                       .                  :   *:                      

Mb1282|M.bovis_AF2122/97            -----------ESD--GDADD-DDYVEYILRREPEEDCD-----------
Rv1250|M.tuberculosis_H37Rv         -----------ESD--GDADD-DDYVEYILRREPEEDCD-----------
MMAR_4192|M.marinum_M               DRGDYGYGDYGEQDDFGEQDDYDDYVEFVLRPEPAVGTHRHTE-------
MAV_1387|M.avium_104                ----------YGGDYHDDYDDDDAYVELILVREPEPEAQQR---------
Mflv_2221|M.gilvum_PYR-GCK          --------PFDPDHPLDWADGEDDYVEYEVSREEFDRLATDGTADGAAYN
MSMEG_5046|M.smegmatis_MC2_155      ----------EPEHAGDYPD-DDEYVEIILSSD-----------------
TH_3965|M.thermoresistible__bu      ----------QPDADAQYLDEHDDYLVIELARP-----------------
MAB_1396|M.abscessus_ATCC_1997      --------------------------------------------------
Mvan_4014|M.vanbaalenii_PYR-1       --------------------------------------------------
MUL_0911|M.ulcerans_Agy99           --------------------------------------------------
MLBr_01562|M.leprae_Br4923          --------------------------------------------------
                                                                                      

Mb1282|M.bovis_AF2122/97            ------TQPLRASR---PAAAAASRSGAGGPLAVSWSTSAQGMPP-----
Rv1250|M.tuberculosis_H37Rv         ------TQPLRASR---PAAAAASRSGAGGPLAVSWSTSAQGMPP-----
MMAR_4192|M.marinum_M               -----IRRPLSGASGNGPAVAGRGQQPHSARFEKWRDDAADGHAAPIEHN
MAV_1387|M.avium_104                -----AGQPRRPQPTPAPPADVRRRDPVESRRSVLDERPAQVQPIGFAHN
Mflv_2221|M.gilvum_PYR-GCK          ITEDFTEDITDVLDTVVEAPPAPADSTPSQQWRDLVDQLLDVSSPPGAPR
MSMEG_5046|M.smegmatis_MC2_155      ------------------PPEDPPTDPQDDRWQHILDRLMQDAPP-----
TH_3965|M.thermoresistible__bu      ------------------DPNPRTDIAVTAVIPALRPTLRPTLRPSLGPP
MAB_1396|M.abscessus_ATCC_1997      -------------------------PGGSQVGAVPLDDVVSVED------
Mvan_4014|M.vanbaalenii_PYR-1       --------------------GDATARAAPLSLRPWGDASVSS--------
MUL_0911|M.ulcerans_Agy99           -----------------IALAAAIVVGWLLPARAGQPTPAQTEPALAQV-
MLBr_01562|M.leprae_Br4923          ------------------------YTPEQVAYAQEVKEAVDAGEL-----
                                                                                      

Mb1282|M.bovis_AF2122/97            --GPPGRRAWQ--------------------ADTESTAPSAL--------
Rv1250|M.tuberculosis_H37Rv         --GPPGRRAWQ--------------------ADTESTAPSAL--------
MMAR_4192|M.marinum_M               GARVDARRRFRPVAD------------FLPAPDQDDAAGSGHSLP-----
MAV_1387|M.avium_104                GSHVDGGKRLRQVAVRRAPKPGPPADRFTRPPRRHHPGPAGHHLGEGESL
Mflv_2221|M.gilvum_PYR-GCK          NGVGSA--------------------------DAEHPGGGPRV-------
MSMEG_5046|M.smegmatis_MC2_155      --------------------------------EDPLPGRGPQRR------
TH_3965|M.thermoresistible__bu      GG------------------------------PVVQPNNTAALR------
MAB_1396|M.abscessus_ATCC_1997      --------------------------------------------------
Mvan_4014|M.vanbaalenii_PYR-1       --------------------------------------------------
MUL_0911|M.ulcerans_Agy99           --------------------------------------------------
MLBr_01562|M.leprae_Br4923          --------------------------------------------------
                                                                                      

Mb1282|M.bovis_AF2122/97            -----------------------
Rv1250|M.tuberculosis_H37Rv         -----------------------
MMAR_4192|M.marinum_M               -----------------------
MAV_1387|M.avium_104                RGQHHRPDPDDDPTGYGRHSSGN
Mflv_2221|M.gilvum_PYR-GCK          -----------------------
MSMEG_5046|M.smegmatis_MC2_155      -----------------------
TH_3965|M.thermoresistible__bu      -----------------------
MAB_1396|M.abscessus_ATCC_1997      -----------------------
Mvan_4014|M.vanbaalenii_PYR-1       -----------------------
MUL_0911|M.ulcerans_Agy99           -----------------------
MLBr_01562|M.leprae_Br4923          -----------------------