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MSFVIAAPETLVRAASDLANIGSTLGAANAAALGPTTELLAAGADEVSAAIASLFAAHGQAYQAVSAQMS AFHAQFVQTFTAGAGAYASAEAAAAAPLEGLLNIVNTPTQLLLGRPLIGNGANGAPGTGQAGGAGGLLYG NGGAGGSGAPGQAGGPGGAAGLFGNGGAGGAGGDGPGNGAAGGAGGAGGLLFGSGGAGGPGGVGNTGTGG LGGDGGAAGLFGAGGIGGAGGPGFNGGAGGAGGRSGLFEVLAAGGAGGTGGLSVNGGTGGTGGTGGGGGL FSNGGAGGAGGFGVSGSAGGNGGTGGDGGIFTGNGGTGGAGGTGTGNQLVGGEGGAGGAGGNAGILFGAG GIGGTGGTGLGAPDPGGTGGKGGVGGIGGAGALFGPGGAGGTGGFGASSADQMAGGIGGSGGSGGAAKLI GDGGAGGTGGDSVRGAAGSGGTGGTGGLIGDGGAGGAGGTGIEFGSVGGAGGAGGNAAGLSGAGGAGGAG GFGETAGDGGAGGNAGLLNGDGGAGGAGGLGIAGDGGNGGKGGKAGMVGNGGDGGAGGASVVANGGVGGS GGNATLIGNGGNGGNGGVGSAPGKGGAGGTAGLLGLNGSPGLS
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1360c | PE_PGRS24 | - | 100% (603) | PE-PGRS family protein |
| M. bovis AF2122 / 97 | Mb3538 | PE_PGRS54 | e-177 | 56.49% (632) | PE-PGRS family protein |
| M. bovis AF2122 / 97 | Mb3543 | PE_PGRS57 | e-176 | 53.26% (674) | PE-PGRS family protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. gilvum PYR-GCK | Mflv_5091 | - | 1e-120 | 45.53% (615) | triple helix repeat-containing collagen |
| M. tuberculosis H37Rv | Rv1325c | PE_PGRS24 | 0.0 | 99.83% (603) | PE-PGRS family protein |
| M. leprae Br4923 | MLBr_01183 | - | 3e-12 | 37.36% (91) | hypothetical protein MLBr_01183 |
| M. abscessus ATCC 19977 | MAB_4284c | - | 4e-46 | 29.51% (515) | hypothetical protein MAB_4284c |
| M. marinum M | MMAR_5044 | - | 0.0 | 55.62% (667) | PE-PGRS family protein |
| M. avium 104 | MAV_4827 | - | 3e-23 | 44.51% (164) | hypothetical protein MAV_4827 |
| M. smegmatis MC2 155 | MSMEG_0868 | - | 3e-96 | 41.12% (676) | hypothetical protein MSMEG_0868 |
| M. thermoresistible (build 8) | TH_3810 | - | 9e-42 | 40.82% (294) | PUTATIVE - |
| M. ulcerans Agy99 | MUL_0212 | - | 0.0 | 56.60% (652) | PE-PGRS family protein |
| M. vanbaalenii PYR-1 | Mvan_1264 | - | 1e-120 | 50.00% (536) | triple helix repeat-containing collagen |
CLUSTAL 2.0.9 multiple sequence alignment
Mb1360c|M.bovis_AF2122/97 --------------------------------------------------
Rv1325c|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_5044|M.marinum_M --------------------------------------------------
MUL_0212|M.ulcerans_Agy99 --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_1264|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_0868|M.smegmatis_MC2_155 MHERLRERAGGVRKTLSDFAEGAGLKPSDTDDTRSPLRKPKFPAALAPES
TH_3810|M.thermoresistible__bu --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 --------------------------------------------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_4827|M.avium_104 --------------------------------------------------
Mb1360c|M.bovis_AF2122/97 --------------------------------------------------
Rv1325c|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_5044|M.marinum_M --------------------------------------------------
MUL_0212|M.ulcerans_Agy99 --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_1264|M.vanbaalenii_PYR-1 -------------------MMFLAPPGGPGPISAAIQLTSTGSEATEP--
MSMEG_0868|M.smegmatis_MC2_155 PLPDLKPRWERPTTAPDSETPSITQPQGRDTAADPAEQQATSTNTTDQPT
TH_3810|M.thermoresistible__bu --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 --------------------------------------------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_4827|M.avium_104 --------------------------------------------------
Mb1360c|M.bovis_AF2122/97 ------------------------------------------MSFVIAAP
Rv1325c|M.tuberculosis_H37Rv ------------------------------------------MSFVIAAP
MMAR_5044|M.marinum_M ------------------------------------------MSYLIAAP
MUL_0212|M.ulcerans_Agy99 ------------------------------------------MSFVNVTP
Mflv_5091|M.gilvum_PYR-GCK --------------------------------------MVTFGGGATPTP
Mvan_1264|M.vanbaalenii_PYR-1 ------------------------------------WYVVSFGGSGAPTP
MSMEG_0868|M.smegmatis_MC2_155 SDSLGAQPTAQVARQVQAPATDPAPAAPSLRPISGLLSVVTLGTTLIPNA
TH_3810|M.thermoresistible__bu --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 ------------------------------------MSIIDFILNLFRDP
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_4827|M.avium_104 -------------------------------------MNIVLGVSMAPSS
Mb1360c|M.bovis_AF2122/97 ----------------------------------------ETLVRAASDL
Rv1325c|M.tuberculosis_H37Rv ----------------------------------------ETLVRAASDL
MMAR_5044|M.marinum_M ----------------------------------------ELMQSAAADL
MUL_0212|M.ulcerans_Agy99 ----------------------------------------EAVAAAASDL
Mflv_5091|M.gilvum_PYR-GCK ----------------------------------------TSLGAAAVDL
Mvan_1264|M.vanbaalenii_PYR-1 ----------------------------------------NNLAASLVDL
MSMEG_0868|M.smegmatis_MC2_155 PTEPADMPGVWAVMAWARRQPMYSDPAMRTTVNPQAQLPVPTVASAVLDP
TH_3810|M.thermoresistible__bu --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 ------------------------------------VEAASYVADPEAAL
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_4827|M.avium_104 ----------------------------------------IQMVVLEGEY
Mb1360c|M.bovis_AF2122/97 AN----------------------IGSTLG-----------AANAAALGP
Rv1325c|M.tuberculosis_H37Rv AN----------------------IGSTLG-----------AANAAALGP
MMAR_5044|M.marinum_M AG----------------------IESALS-----------AANVSAAVP
MUL_0212|M.ulcerans_Agy99 TG----------------------IGSVLG-----------EANAVAARA
Mflv_5091|M.gilvum_PYR-GCK S------------------------GTSCG----------LICNGQDGTG
Mvan_1264|M.vanbaalenii_PYR-1 S------------------------GTSCG----------LICNGQDGTG
MSMEG_0868|M.smegmatis_MC2_155 TQIVNWLIYQPLHAAGQQFWVVSPIGSTLGGVINTISGQYLIGNGINGTA
TH_3810|M.thermoresistible__bu --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 AN----------------------AGLSAVS----------AAQVGAVMP
MLBr_01183|M.leprae_Br4923 ----------------------------MP--------------------
MAV_4827|M.avium_104 AD-----------------------GATVEED---------AIDVTGADD
Mb1360c|M.bovis_AF2122/97 TT-------ELLAAGADEVSAAIASLFAAHGQAYQAVSAQMSAFHAQFVQ
Rv1325c|M.tuberculosis_H37Rv TT-------ELLAAGADEVSAAIASLFAAHGQAYQAVSAQMSAFHAQFVQ
MMAR_5044|M.marinum_M TT-------QILAAGADEVSAAIAALFGAHAQAYQALGSHVTAFHQEFVQ
MUL_0212|M.ulcerans_Agy99 TT-------TVLAAGGDEVSAAIAALFSFHGQSYQTLGAQAEAFHAQFAQ
Mflv_5091|M.gilvum_PYR-GCK QN-----GGILFGNGGSGWNSDVVGMDGGNGGNGGLFGGNGGNGGNGLGG
Mvan_1264|M.vanbaalenii_PYR-1 QN-----GGILFGNGGSGWNSEIAGVSGGNGGNAGLFGGNGGNGGNGLGS
MSMEG_0868|M.smegmatis_MC2_155 DNPNGGTGGLLFGDGGHGYDGSAAGLAGGNGGNAGLFG-NGGNGGVGWAG
TH_3810|M.thermoresistible__bu -------------VDGDGGSGGRTGLFSKLSR-----GGDGGDGGLGGNG
MAB_4284c|M.abscessus_ATCC_199 VVAESVASNYGYQSQWVNTGNPIHDLSGNLQNYYAAQPDGPSILSPSLLS
MLBr_01183|M.leprae_Br4923 ---------LFLNAEPQALTAAANTLEG-LSAATVASNAAAAQLTTEIAP
MAV_4827|M.avium_104 AATASAPDRVISAILGTREGAADAGLQLSSIGVTWTDQLEAAALRDALAA
:
Mb1360c|M.bovis_AF2122/97 TFTAGAGAYASAEAAAAAPLEGLLNIVNTPTQLLLG--RPLIG--NGANG
Rv1325c|M.tuberculosis_H37Rv TFTAGAGAYASAEAAAAAPLEGLLNIVNTPTQLLLG--RPLIG--NGANG
MMAR_5044|M.marinum_M ALNSGAASYANAEAASIAPLQALYDLVNAPTQALLG--RPLIG--NGANG
MUL_0212|M.ulcerans_Agy99 LMANGAGTYASAEAANAAPFQGLLGAVNAPVQTLTG--RPLIG--NGANG
Mflv_5091|M.gilvum_PYR-GCK GNGGNGGNAGAFALFGNGGNGGNGGVGVVGATGAVG--APGVAGATGATG
Mvan_1264|M.vanbaalenii_PYR-1 GDGGNGGDAGLFSLFGRGGNGGNGGVGIAGATGAVG--APGVAGATGATG
MSMEG_0868|M.smegmatis_MC2_155 LDGGNGGSGG--LLMGIGGAGGAGGVGADGTSAHVDGGTGGTGGTGGGTG
TH_3810|M.thermoresistible__bu GHGGGTGIISLLSLAGNGGNGGN-GYRTTDNNALDG------G--HGGNG
MAB_4284c|M.abscessus_ATCC_199 PRDNDFLSHNDTDFASHNPIASGNQVMSPSGNVDSFNRGPLLDLSFGDLQ
MLBr_01183|M.leprae_Br4923 PAADDVSILLAHFFSGHGR-----QYQAHASQGATN--------------
MAV_4827|M.avium_104 RRIDNVMLVSAFLAAAALAQNVGGAMGYERTAVLLVEPDTATLAVVETSD
.
Mb1360c|M.bovis_AF2122/97 APG--TGQAGGAGGLLYGNGGAGGSGAPGQAGGPG---------------
Rv1325c|M.tuberculosis_H37Rv APG--TGQAGGAGGLLYGNGGAGGSGAPGQAGGPG---------------
MMAR_5044|M.marinum_M APG--TGQNGGDGGLLFGNGGAGGSGADGQNGGAG---------------
MUL_0212|M.ulcerans_Agy99 APG--TGANGGAGGWLIGNGGAGGSGAPGLNGGAG---------------
Mflv_5091|M.gilvum_PYR-GCK VTSGVVGGNGEDAVGYGATGAAGAAGAAGAAGAAG--------------A
Mvan_1264|M.vanbaalenii_PYR-1 VTSNVTGGNGADAVGYGATGAAGAAGAAGAAGKAG--------------A
MSMEG_0868|M.smegmatis_MC2_155 GTGGIGGTGGGLFGLLGHSGSTGAAGAAGNGGDGGNGGFGYVLIAGPNVT
TH_3810|M.thermoresistible__bu ------GNVG--FFSLFNLGGAGGWGGSGVDG------------------
MAB_4284c|M.abscessus_ATCC_199 FGNRDTTAIGDGAVAVGGSNSGPIASGQGSTAVNG--------------D
MLBr_01183|M.leprae_Br4923 -------HQDLIQSLLTSSSAYAGTETANHDSL-----------------
MAV_4827|M.avium_104 GSIPDVYKQQIRAESYGDAAGQLSAMVAGLEKLES--------------L
. .
Mb1360c|M.bovis_AF2122/97 -GAAGLFGNGGAGGAGGDG---PGNGAAGGAGGAGG--------------
Rv1325c|M.tuberculosis_H37Rv -GAAGLFGNGGAGGAGGDG---PGNGAAGGAGGAGG--------------
MMAR_5044|M.marinum_M -GNAGFFGSGGAGGAGGNTDLFGNNGAVGGAGGAGG--------------
MUL_0212|M.ulcerans_Agy99 -GAAGLIGTGGAGGAGGSSSTVN--GGLGGTGGAGG--------------
Mflv_5091|M.gilvum_PYR-GCK VGSAGAAGEAGETGTWG---NAGLPGKAGDAGGAG---------------
Mvan_1264|M.vanbaalenii_PYR-1 VGSAGTAGSAGAPGVWG---NAGLPGAAGAAGGAG---------------
MSMEG_0868|M.smegmatis_MC2_155 VGSETRGGTGGAGGTGGQS-TAAGPGKGGGGGGGGGGAILIGANGGTVDG
TH_3810|M.thermoresistible__bu VDVVGGNPDGGTPGAHGES---HTPGVYTDRQGEDG--------------
MAB_4284c|M.abscessus_ATCC_199 VRDSNIINADHGSNVGVDQSQTRVGGDYTNVSGHGSADIDKS-------V
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_4827|M.avium_104 PGGLLLVGSGVDVAPLKQVLQTTTFLDVSVAEEPET--------------
Mb1360c|M.bovis_AF2122/97 LLFGSGGAGGPGG-------------------------------------
Rv1325c|M.tuberculosis_H37Rv LLFGSGGAGGPGG-------------------------------------
MMAR_5044|M.marinum_M WLIGSGGAGGTGGIGAFNGGAGGAGGSAWLFGTGGVGGTGGIGTLGVGGA
MUL_0212|M.ulcerans_Agy99 WLLGNGGAGGAG------------GASAIPLGP-----------------
Mflv_5091|M.gilvum_PYR-GCK -AVGAAGAAG------TVGTAGATGGTG----------------------
Mvan_1264|M.vanbaalenii_PYR-1 -AIGTAGVAG------AAGTAGATGGTG----------------------
MSMEG_0868|M.smegmatis_MC2_155 HAIGGNGGNGGNGSTTAAGGNGGTGGTGRVIAEGTGSTAEGTA-------
TH_3810|M.thermoresistible__bu -EDGTG--------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 TVVDDHSQRNTTNIN-----------------------------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_4827|M.avium_104 -ALARGAALAAAN-------------------------------------
Mb1360c|M.bovis_AF2122/97 ------------------------------------VGNTGTGGLGGDGG
Rv1325c|M.tuberculosis_H37Rv ------------------------------------VGNTGTGGLGGDGG
MMAR_5044|M.marinum_M GGAGGGSGVLSFADGGAGGFGGSGANAGGVGGSGGAAGIFGTGGAGGTGG
MUL_0212|M.ulcerans_Agy99 -------------------------------------DLIGKGGAGGPG-
Mflv_5091|M.gilvum_PYR-GCK --------------------------------TGANGGAGGVGGVGGTGA
Mvan_1264|M.vanbaalenii_PYR-1 --------------------------------VGGNGGAGQAGGIGGTGA
MSMEG_0868|M.smegmatis_MC2_155 --------------------------------TGGDGGHSTGTGIGGNGG
TH_3810|M.thermoresistible__bu ---------------------------------------TGIGGRGGNGG
MAB_4284c|M.abscessus_ATCC_199 --------------------------------DSFNTDRSTNIGSGNTTN
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_4827|M.avium_104 --------------------------------APLFASSTAALAYAQDPG
Mb1360c|M.bovis_AF2122/97 --------------------------------------------------
Rv1325c|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_5044|M.marinum_M AGGTNGLEIGQVSVGGAGGDGGRGGWLLGIGGSGGFGGFGQGPSGGIGGD
MUL_0212|M.ulcerans_Agy99 --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK AG----------------------------------------AAGGAGGL
Mvan_1264|M.vanbaalenii_PYR-1 AG----------------------------------------AAGQAGTA
MSMEG_0868|M.smegmatis_MC2_155 IGSVYAY--------------------------GNNGAVSGTATGGRGGD
TH_3810|M.thermoresistible__bu S-------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 --------------------------------------------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_4827|M.avium_104 TG------------------------------------------------
Mb1360c|M.bovis_AF2122/97 --AAGLFGAGGIG-------------------------------------
Rv1325c|M.tuberculosis_H37Rv --AAGLFGAGGIG-------------------------------------
MMAR_5044|M.marinum_M GGDAGLFGVGGIGGTGGTGFSGVGGNAGAGGDGGLLWGSGGAGARGGQGG
MUL_0212|M.ulcerans_Agy99 ----GLFGAGGLG-------------------------------------
Mflv_5091|M.gilvum_PYR-GCK GETGTTGGAGGVGGQ--------------GTAGGTGGVGGIGGAGSTGAV
Mvan_1264|M.vanbaalenii_PYR-1 GETGVTGGVGGIGGQ--------------GTEGGTGGVGGVGGVGATGGA
MSMEG_0868|M.smegmatis_MC2_155 GIDGGTGGAGGMGEIY------------SGADGEATGISAGGDGGSATGA
TH_3810|M.thermoresistible__bu -----SSGTHPMAE------------------------------------
MAB_4284c|M.abscessus_ATCC_199 -TEIGSHNQANIGTS-----------------------------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_4827|M.avium_104 --AVDQYSLPDYLYVP---------------------------------V
Mb1360c|M.bovis_AF2122/97 -GAGGPG------FNGG-----------------AGGAGGRS--------
Rv1325c|M.tuberculosis_H37Rv -GAGGPG------FNGG-----------------AGGAGGRS--------
MMAR_5044|M.marinum_M AGAGGIGG-----AGGGGGLFGGDGGAGGVGGTGAGGPGGAGGVGGDAGL
MUL_0212|M.ulcerans_Agy99 -GAGGFGG-----SGGG-----------------AGGQGGAG--------
Mflv_5091|M.gilvum_PYR-GCK GGVGGKG----IQGGQG-------------LQGGKGGDGGAGGKGGDADS
Mvan_1264|M.vanbaalenii_PYR-1 GGVGGKG----IQGGQG-------------LQGGQGGDGGTGGTGGDATS
MSMEG_0868|M.smegmatis_MC2_155 DSLGGRGGTSWVQAGYGPTTGGKASGTAKAGHGGKASDGGKGGNGGDALV
TH_3810|M.thermoresistible__bu ---DG---------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 TSAGGSAAVG----------------------GNAGLAGNAG--------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_4827|M.avium_104 DPEPGDDE---------------------LAYSAVGEEDAESP-------
Mb1360c|M.bovis_AF2122/97 ----------------------------------GLFEVLAAGGA-----
Rv1325c|M.tuberculosis_H37Rv ----------------------------------GLFEVLAAGGA-----
MMAR_5044|M.marinum_M FGVGGAGGVGGTGVGFPTDPGLSFGGQGGAGGRGGLLIGLGGNGGTGGFS
MUL_0212|M.ulcerans_Agy99 ----------------------------------GLLSGLVGAGG-----
Mflv_5091|M.gilvum_PYR-GCK MGS------------------------------AGATGGKGGNGGNGGRG
Mvan_1264|M.vanbaalenii_PYR-1 MGE------------------------------AGATGGKGGNGGNGGRG
MSMEG_0868|M.smegmatis_MC2_155 MAAGATGVATGNTA------------IGGNGGAASANGAVGGNGGFTNIA
TH_3810|M.thermoresistible__bu ----------------------------------EHVKALDGRPG-----
MAB_4284c|M.abscessus_ATCC_199 ---------------------------------LAGNAGLAGNAG-----
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_4827|M.avium_104 -----------------------------TVVIEKLFLPEDSEPRRRP--
Mb1360c|M.bovis_AF2122/97 -----------------------GGTGGLS--------------------
Rv1325c|M.tuberculosis_H37Rv -----------------------GGTGGLS--------------------
MMAR_5044|M.marinum_M GPLSAGAGGGDGGAGGGVGLIGFGGAGGFGGASGF---------------
MUL_0212|M.ulcerans_Agy99 ---------------------GHGGTGGYG--------------------
Mflv_5091|M.gilvum_PYR-GCK GLFG---------------KGGNAGNGAD---------------------
Mvan_1264|M.vanbaalenii_PYR-1 SLFG---------------RGGNAGNGGN---------------------
MSMEG_0868|M.smegmatis_MC2_155 AIHGSITDSSATSGHGGAAQGGNGGNGGNGWVQAYDPNGPAGTTIDKGKA
TH_3810|M.thermoresistible__bu --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 ----------------------LAGNAGLAG-------------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_4827|M.avium_104 --------------------------------------------------
Mb1360c|M.bovis_AF2122/97 -----VNGGTGGTG------------------GTGGGGGL----------
Rv1325c|M.tuberculosis_H37Rv -----VNGGTGGTG------------------GTGGGGGL----------
MMAR_5044|M.marinum_M --GTGGAGGVGGAGGALFGVGGVGGNGAWGAGGIGGDGGVGGA-------
MUL_0212|M.ulcerans_Agy99 ----GGAGGAGATG---------GGN----TGGIGGDGGS----------
Mflv_5091|M.gilvum_PYR-GCK -GGTGGAGGAGGTGG---------------TGGAGGTGG-----------
Mvan_1264|M.vanbaalenii_PYR-1 -GGTGGNGGNGGTGG---------------TGGNGGTGG-----------
MSMEG_0868|M.smegmatis_MC2_155 AGGNGGDGGFNGTGGA--------------TGGRGGDGAGASVWKANGQH
TH_3810|M.thermoresistible__bu -----LDGGNGSHG------------------------------------
MAB_4284c|M.abscessus_ATCC_199 --NAGLAGNAGLAGN----------------AGLAGNAG-----------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_4827|M.avium_104 --VLLVGSGLAVVGIS---------------AVLALEIALAIG-------
Mb1360c|M.bovis_AF2122/97 -------FSNGGAGGAGGFGVSGSAGGNGGTGGDGGIFTGNGGTGGAGGT
Rv1325c|M.tuberculosis_H37Rv -------FSNGGAGGAGGFGVSGSAGGNGGTGGDGGIFTGNGGTGGTGGT
MMAR_5044|M.marinum_M --GSALGFGLGGAGGAGGASGLG-DGGAGGTGGAGGLLGGNGGGGGAGGA
MUL_0212|M.ulcerans_Agy99 ---AGMLFSNSGAGGAGGASELA-DGGAGGAGGNGGWLLSNGGVGGAGGA
Mflv_5091|M.gilvum_PYR-GCK ------TGGTGGIGGAGSTGGTGGTGGTGGTGGTGGTG-GTGGTGGTGGT
Mvan_1264|M.vanbaalenii_PYR-1 ------TGGTGGIGGAGSTGGTGGTGGTGGTGGTGGTG-GTGGTGGTGGT
MSMEG_0868|M.smegmatis_MC2_155 STGQTDTGGNGGRGGDGGTFVNAGANGNGGAGGAGGVSEGEGGTGGHGGD
TH_3810|M.thermoresistible__bu --------GNGGHGGRGGFLGIGGSGGWGGHGGNGGDTDADGGNGGDGGN
MAB_4284c|M.abscessus_ATCC_199 ------LAGNAGLAGNAGLAGNAGLAGNAGLAGNAGLAGNAGLAGNAGLA
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_4827|M.avium_104 ----IRTTGTVALQPTPNQHLIVPTEQAPAPPPVQASAPQPKISVPEPVA
Mb1360c|M.bovis_AF2122/97 G-----TGNQLVGGEGGAGGAGGNAGILFGAGGIGGTGGTG---------
Rv1325c|M.tuberculosis_H37Rv G-----TGNQLVGGEGGAGGAGGNAGILFGAGGIGGTGGTG---------
MMAR_5044|M.marinum_M G--AVGFLDNTADGAGGAGGAGGSGGLLFGDGGVGGAGGAGGISTSSSVN
MUL_0212|M.ulcerans_Agy99 GADAVGPPFGIPAGSGSGGGAGGAGGVFFGNGGAGGAG------------
Mflv_5091|M.gilvum_PYR-GCK G---------GKGGTGGTGGAGGTG----GDGGTGGTGGTGGTG------
Mvan_1264|M.vanbaalenii_PYR-1 G---------GKGGTGGTGGDGGTG----GTGGTGGTGGTGGTG------
MSMEG_0868|M.smegmatis_MC2_155 G---------GRGGDGALGGNGGTGGVGLGNGGKGGNGGNGGNGGTY---
TH_3810|M.thermoresistible__bu G------------GSAGRGGTGGLRGVFGINGGNGRAG------------
MAB_4284c|M.abscessus_ATCC_199 G-------NAGLAGNAGLAGNAGLAGNAGLAGNAGLAGNAAVAG------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_4827|M.avium_104 APKPLSPPVAAPLPAAPPPAAPPLPEAPPIPAAPPVVPVPVVVP------
Mb1360c|M.bovis_AF2122/97 ---------------------------------LGAPDPGG---------
Rv1325c|M.tuberculosis_H37Rv ---------------------------------LGAPDPGG---------
MMAR_5044|M.marinum_M NGGAGGAGGNAGGLFGSGGAGGIGGAVGTGGTVAGAGGDGGGAGWVGNAG
MUL_0212|M.ulcerans_Agy99 ----------------------------------GTGGDGG---------
Mflv_5091|M.gilvum_PYR-GCK ----------------------------------GTGGTGGTGGAG----
Mvan_1264|M.vanbaalenii_PYR-1 ----------------------------------GTGGTGGTGGAG----
MSMEG_0868|M.smegmatis_MC2_155 ----------------------------VDPSHTGAGGNGGNGGAGRIRV
TH_3810|M.thermoresistible__bu --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 ----------------------------------NAAVAGN---------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_4827|M.avium_104 --------------------------------------------------
Mb1360c|M.bovis_AF2122/97 ---------TGGKGGVGG----IGGAGALFGPGG----------------
Rv1325c|M.tuberculosis_H37Rv ---------TGGKGGVGG----IGGAGALFGPGG----------------
MMAR_5044|M.marinum_M NGGAGGDGWTNGNGGDGG----DGGDAVLVGNGG----------------
MUL_0212|M.ulcerans_Agy99 -----------GTGGAGG----AAGNGVLIGNGG----------------
Mflv_5091|M.gilvum_PYR-GCK -------DGTGGTGGTGG----TGGQGGQGGQGG----------------
Mvan_1264|M.vanbaalenii_PYR-1 -------DGLGGTGGTGG----TGGFGGQGGQGG----------------
MSMEG_0868|M.smegmatis_MC2_155 NNGTATGTATGGNGGNGGNGDADGHRGGKGGDGGEALIRATVIGSNASGT
TH_3810|M.thermoresistible__bu ------------LGGRGX-----------XXXGG----------------
MAB_4284c|M.abscessus_ATCC_199 -------AAVAGNAAVGG----VLNTGVSGAIGG----------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_4827|M.avium_104 --------PVPVPVPVRIPVPDPVSPPQLLAPPR----------------
Mb1360c|M.bovis_AF2122/97 -AGGTGGFG-----------------------------------------
Rv1325c|M.tuberculosis_H37Rv -AGGTGGFG-----------------------------------------
MMAR_5044|M.marinum_M -NGGNGGTGLVAGSTGTGGTSGFLLGLDGFNASGSTSPLHILQQQTLNAI
MUL_0212|M.ulcerans_Agy99 -NGGIG--------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK -TGGTGGQGG-LGGGGGTG-------------------------------
Mvan_1264|M.vanbaalenii_PYR-1 -TGGTGGQGG-LGGVGGTG-------------------------------
MSMEG_0868|M.smegmatis_MC2_155 ATGGDGGNGGTLGATNGTGGAATIVAYNVVQANPQASGT-----------
TH_3810|M.thermoresistible__bu --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 --------------------------------------------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_4827|M.avium_104 --------------------------------------------------
Mb1360c|M.bovis_AF2122/97 --------------------------------------------------
Rv1325c|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_5044|M.marinum_M NAPFDALTGRPLIGNGTPGAAGSGADGTAGGWLLGNGGAGGSGADGQNGG
MUL_0212|M.ulcerans_Agy99 --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_1264|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_0868|M.smegmatis_MC2_155 --------------------------------------------------
TH_3810|M.thermoresistible__bu --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 --------------------------------------------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_4827|M.avium_104 --------------------------------------------------
Mb1360c|M.bovis_AF2122/97 --------------------------------------------------
Rv1325c|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_5044|M.marinum_M AGGNAGFFGSGGAGGAGGNTDLFGNNGAVGGAGGAGGWLIGSGGAGGTGG
MUL_0212|M.ulcerans_Agy99 --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_1264|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_0868|M.smegmatis_MC2_155 --------------------------------------------------
TH_3810|M.thermoresistible__bu --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 --------------------------------------------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_4827|M.avium_104 --------------------------------------------------
Mb1360c|M.bovis_AF2122/97 --------------------------------------------------
Rv1325c|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_5044|M.marinum_M IGAFNGGAGGAGGSAWLFGTGGVGGTGGIGTLGVGGAGGAGGGSGVLSFA
MUL_0212|M.ulcerans_Agy99 --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_1264|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_0868|M.smegmatis_MC2_155 --------------------------------------------------
TH_3810|M.thermoresistible__bu --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 --------------------------------------------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_4827|M.avium_104 --------------------------------------------------
Mb1360c|M.bovis_AF2122/97 ---------------------ASSADQMAGGIGGSGGSGGA---------
Rv1325c|M.tuberculosis_H37Rv ---------------------ASSADQMAGGIGGSGGSGGA---------
MMAR_5044|M.marinum_M DGGAGGFGGSGANAGGVGGSGGAAGIFGTGGAGGTGGAGGTNGLEIGQVS
MUL_0212|M.ulcerans_Agy99 ---------------------GAAGLWGTGGTGGSGGSGGT---------
Mflv_5091|M.gilvum_PYR-GCK ---------------------GQGGTGGTGGQGGTGGTGGTGGTG-----
Mvan_1264|M.vanbaalenii_PYR-1 ---------------------GTGGTGGTGGQGGTGGTGGTGGTG-----
MSMEG_0868|M.smegmatis_MC2_155 ------------------ATDGHGGSGINGGHGGNGGQGTIEANGPSAVA
TH_3810|M.thermoresistible__bu ------------------------------GVGAAVRS-GN---------
MAB_4284c|M.abscessus_ATCC_199 --------------------SSHVGGAINESLGGSGSVGGSTAVG-----
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_4827|M.avium_104 ----------------LSVPQPVQPPVRVPQPPSPPQVGGTVPQS-----
Mb1360c|M.bovis_AF2122/97 --------------------------------------------------
Rv1325c|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_5044|M.marinum_M VGGAGGDGGRGGWLLGIGGSGGFGGFGQGPSGGIGGDGGDAGLFGVGGIG
MUL_0212|M.ulcerans_Agy99 -------------------------------------------------G
Mflv_5091|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_1264|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_0868|M.smegmatis_MC2_155 SG-----------------------------------------------I
TH_3810|M.thermoresistible__bu --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 --------------------------------------------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_4827|M.avium_104 --------------------------------------------------
Mb1360c|M.bovis_AF2122/97 --------------------------------------------------
Rv1325c|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_5044|M.marinum_M GTGGTGFSGVGGNAGAGGDGGLLWGSGGAGARGGQGGAGAGGIGGAGGGG
MUL_0212|M.ulcerans_Agy99 ATG--GFSGL----------------------------------------
Mflv_5091|M.gilvum_PYR-GCK GTGGAGGDGG---------------------------------------L
Mvan_1264|M.vanbaalenii_PYR-1 GTGGAGGDGG---------------------------------------L
MSMEG_0868|M.smegmatis_MC2_155 GAGGNGGDGI---------------------------------------D
TH_3810|M.thermoresistible__bu --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 -------------------------------------------------G
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_4827|M.avium_104 -------------------------------------------------P
Mb1360c|M.bovis_AF2122/97 AKLIGDGGAGGTG-------------------------------------
Rv1325c|M.tuberculosis_H37Rv AKLIGDGGAGGTG-------------------------------------
MMAR_5044|M.marinum_M GLFGGDGGAGGVGGTGAGGPGGAGGVGGDAGLFGVGGAGGVGGTGVGFPT
MUL_0212|M.ulcerans_Agy99 -LASGDGGAGGAG-------------------------------------
Mflv_5091|M.gilvum_PYR-GCK GGLGGFGGSGGTGG------------------------------------
Mvan_1264|M.vanbaalenii_PYR-1 GGLGGFGGVGGTGG------------------------------------
MSMEG_0868|M.smegmatis_MC2_155 GGLGGNGGDGVVNT------------------------------------
TH_3810|M.thermoresistible__bu GVFSGGGGTPSAG-------------------------------------
MAB_4284c|M.abscessus_ATCC_199 GAHTGVGGGVSTGVG-----------------------------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_4827|M.avium_104 PQHQTPPGEGTPPK------------------------------------
Mb1360c|M.bovis_AF2122/97 ---------------GDSVRGAAG---------------SGGTGGTGG--
Rv1325c|M.tuberculosis_H37Rv ---------------GDSVRGAAG---------------SGGTGGTGG--
MMAR_5044|M.marinum_M DPGLSFGGQGGAGGRGGLLIGLGGNGGTGGFSGPLSAGAGGGDGGAGGGV
MUL_0212|M.ulcerans_Agy99 ----------GAGGAGGLLDGLVG--------------AGGGDGGAGG--
Mflv_5091|M.gilvum_PYR-GCK --------QGGLGGPGGSTGGAGGAGG------------QAGTAGKGGLF
Mvan_1264|M.vanbaalenii_PYR-1 --------QGGQGGPGGSTGGAGGAGG------------QAGVAGKGGLF
MSMEG_0868|M.smegmatis_MC2_155 --------TANAANPGSATGTATGGDGG----------KATGTASQGGNG
TH_3810|M.thermoresistible__bu --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 --------------VGSHVGGGISES-------------LGGSGSVGG--
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_4827|M.avium_104 ---------------------------------------PDGPGNYGG--
Mb1360c|M.bovis_AF2122/97 -------------------------------LIGDGGAGGA---------
Rv1325c|M.tuberculosis_H37Rv -------------------------------LIGDGGAGGA---------
MMAR_5044|M.marinum_M GLIGFGGAGGFGGASGFGTGGAGGVGGAGGALFGVGGVGGNGAWGAGGIG
MUL_0212|M.ulcerans_Agy99 ---------------------------NAGTLFGSGGVGGD---------
Mflv_5091|M.gilvum_PYR-GCK G------------------------GSGSAGKAGATGAAGAS--------
Mvan_1264|M.vanbaalenii_PYR-1 G------------------------GSGSAGTAGVTGASGAS--------
MSMEG_0868|M.smegmatis_MC2_155 GP--------------------SWVQSGYGSTLGGNATGTAT--------
TH_3810|M.thermoresistible__bu --------------------------------FGVPTTIQFP--------
MAB_4284c|M.abscessus_ATCC_199 -----------------------------STAVGGGAHTGVG--------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_4827|M.avium_104 ------------------------------GHVPTPGAGGSG--------
Mb1360c|M.bovis_AF2122/97 -----------------------GGTGIE--FGSVGGAG--------GAG
Rv1325c|M.tuberculosis_H37Rv -----------------------GGTGIE--FGSVGGAG--------GAG
MMAR_5044|M.marinum_M GDGGVGGAGSALGFGLGGAGGAGGASGLG--DGGAGGTG--------GAG
MUL_0212|M.ulcerans_Agy99 -----------------------GGSGHG--NGGDGGGG--------GNA
Mflv_5091|M.gilvum_PYR-GCK -----------------------GGKGAQGATGAQGATG------AQGAT
Mvan_1264|M.vanbaalenii_PYR-1 -----------------------GGKGAQGATGAQGATG------AQGAT
MSMEG_0868|M.smegmatis_MC2_155 -----------------------AGKGGEASNGGVAGNGGNALVMAAGTT
TH_3810|M.thermoresistible__bu -----------------------AG----------------------SCT
MAB_4284c|M.abscessus_ATCC_199 -----------------------GGVSTGVGVGSHVGGG---ISESLGGS
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_4827|M.avium_104 -----------------------GSGGGHVPTPGAGGSG--------GSG
Mb1360c|M.bovis_AF2122/97 GNAAGLSGAGGAGGAGGFG-------ETAGDG----------------GA
Rv1325c|M.tuberculosis_H37Rv GNAAGLSGAGGAGGAGGFG-------ETAGDG----------------GA
MMAR_5044|M.marinum_M GLLGGNGGGGGAGGAGAVGFLDNTADGAGGAG----------------GA
MUL_0212|M.ulcerans_Agy99 GLLFSDAGGGGFGGFGLA--------GGGGTG----------------GS
Mflv_5091|M.gilvum_PYR-GCK G-ATGAAGKAGATGAAGAAG------AAGSAG-----------TTGAQGS
Mvan_1264|M.vanbaalenii_PYR-1 G-ATGASGAQGSAGSAGSAG------VAGSAG-----------TTGAQGS
MSMEG_0868|M.smegmatis_MC2_155 GVATGNTATGGDGGAATTAG------ATGGAGGFSNIAAIHGAITDSTAI
TH_3810|M.thermoresistible__bu SRAVSREGIMPSSRAASAR-------------------------------
MAB_4284c|M.abscessus_ATCC_199 GSVGGSTAVGGGAHTGVGGG------VNTGVG-------------VGSHV
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_4827|M.avium_104 GGHVPTPGTGGPGGTGGSGG----------------------------GH
Mb1360c|M.bovis_AF2122/97 GGNAGLLNGD----GGAGGAGGLGIAG-----------DGGNGGKGGKAG
Rv1325c|M.tuberculosis_H37Rv GGNAGLLNGD----GGAGGAGGLGIAG-----------DGGNGGKGGKAG
MMAR_5044|M.marinum_M GGSGGLLFGDGG-VGGAGGAGGISTSSSVN--------NGGAGGAGGNAG
MUL_0212|M.ulcerans_Agy99 GGDAGWLGS-----GGAGGAGGISVNG-----------DAGAGGAGGTSG
Mflv_5091|M.gilvum_PYR-GCK AGTNGA-NGANGSQGAAGKAGATGTTGATG--------AAGEDGDAGSGG
Mvan_1264|M.vanbaalenii_PYR-1 AGTNGA-NGANGSQGAAGKAGATGTTGATG--------AAGDAGDPGSEA
MSMEG_0868|M.smegmatis_MC2_155 SGHGGAGNGGNGGKGADGWVQAYDPAGPVGSKIANSSAVAGNGGDGGVNG
TH_3810|M.thermoresistible__bu ----------------AGAACASSTSR--------------------SRR
MAB_4284c|M.abscessus_ATCC_199 GGGISESLGGSGSVGGSTAVGGGAHTSAIN---------DALGGSGSVGG
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_4827|M.avium_104 VPTPGAGTPGGSGGGHLPFPGAGSTPG------------GSGGGHLPTPG
Mb1360c|M.bovis_AF2122/97 -MVGNGGDG------GAGGAS-------VVANG-----------------
Rv1325c|M.tuberculosis_H37Rv -MVGNGGDG------GAGGAS-------VVANG-----------------
MMAR_5044|M.marinum_M GLFGSGGAGGIGGAVGTGGTV-------AGAGGDGGGAGWVGNAGNGGAG
MUL_0212|M.ulcerans_Agy99 QLLGDGGAG------GAGGEA-------ELAAG-----------------
Mflv_5091|M.gilvum_PYR-GCK SG-INGGAG------GAGG-----------AGGEG---------------
Mvan_1264|M.vanbaalenii_PYR-1 VD-INGGAG------GAGG-----------AGGEG---------------
MSMEG_0868|M.smegmatis_MC2_155 TGGASGGDG------GNGGNTSVWKSGGQTADGEH---------------
TH_3810|M.thermoresistible__bu SFCCSRA-------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 STAVGGGAH-------------------TSAIN-----------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_4827|M.avium_104 AGTPGGGLG-----------------------------------------
Mb1360c|M.bovis_AF2122/97 ---------GVGGSGGNATLIGNGGNG-----GNGGVG-------SAPGK
Rv1325c|M.tuberculosis_H37Rv ---------GVGGSGGNATLIGNGGNG-----GNGGVG-------SAPGK
MMAR_5044|M.marinum_M GDGWTNGNGGDGGDGGDVGLFGAGGNG-----GNGGTG-------VTAGT
MUL_0212|M.ulcerans_Agy99 ------GAGGSGGVGGDAVLIGAGGNG-----GNGGPG-------TAKGD
Mflv_5091|M.gilvum_PYR-GCK ------GEGGDGGKGGAGAEGGAGGGGGAGGSGAGGAG-------GAGGS
Mvan_1264|M.vanbaalenii_PYR-1 ------GEGGAGGAGGDGSEGGAGGSGGAGGSGTGGAG-------GAGGS
MSMEG_0868|M.smegmatis_MC2_155 ------NTGGNGGNGGDGSEPGPGGNGAGGAGGNGGTGGTTAGGSGNGGN
TH_3810|M.thermoresistible__bu --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 ------ESMNSSINASHSSSMNESFGSSMGSHGAAGTG--------FEAQ
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_4827|M.avium_104 ---------GFGGGHAPAPGGGLGGGGGHAPAPGGGLG----------GF
Mb1360c|M.bovis_AF2122/97 GGAGGTAGLLGLNGSPGLS-----
Rv1325c|M.tuberculosis_H37Rv GGAGGTAGLLGLNGSPGLS-----
MMAR_5044|M.marinum_M GGTGGSGGLLGPDGINGS------
MUL_0212|M.ulcerans_Agy99 PGSGGAGGLLGVDGLNGLS-----
Mflv_5091|M.gilvum_PYR-GCK GGSGGSGGSGGSGGAAGDSDD---
Mvan_1264|M.vanbaalenii_PYR-1 GGSGGSGGAGGSGGAAGDSD----
MSMEG_0868|M.smegmatis_MC2_155 GGNGGNGGADGTPGTAGTTGANNP
TH_3810|M.thermoresistible__bu ------------------------
MAB_4284c|M.abscessus_ATCC_199 GHAQGHASETAHTTLPGAEHH---
MLBr_01183|M.leprae_Br4923 ------------------------
MAV_4827|M.avium_104 GGGHSGGGLGGLGGGHK-------