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MSFVIAVPETIAAAATDLADLGSTIAGANAAAAANTTSLLAAGADEISAAIAALFGAHGRAYQAASAEAA AFHGRFVQALTTGGAPMRPPRPPP
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1790c | wag22a | - | 100% (94) | hypothetical protein Mb1790c |
| M. bovis AF2122 / 97 | Mb0286c | PE_PGRS3 | 7e-33 | 79.76% (84) | PE-PGRS family protein |
| M. bovis AF2122 / 97 | Mb0287c | PE_PGRS4 | 2e-32 | 79.76% (84) | PE-PGRS family protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. gilvum PYR-GCK | Mflv_0326 | - | 7e-05 | 34.78% (69) | PE domain-containing protein |
| M. tuberculosis H37Rv | Rv1759c | wag22 | 7e-41 | 100.00% (84) | PE-PGRS family protein |
| M. leprae Br4923 | MLBr_01183 | - | 4e-12 | 37.35% (83) | hypothetical protein MLBr_01183 |
| M. abscessus ATCC 19977 | MAB_0664 | - | 6e-07 | 40.58% (69) | PE family protein |
| M. marinum M | MMAR_0608 | - | 2e-27 | 69.41% (85) | PE-PGRS family protein |
| M. avium 104 | MAV_1346 | - | 2e-15 | 52.44% (82) | PE family protein |
| M. smegmatis MC2 155 | MSMEG_0618 | - | 9e-06 | 36.23% (69) | PE family protein |
| M. thermoresistible (build 8) | - | - | - | - | - |
| M. ulcerans Agy99 | MUL_0570 | - | 1e-27 | 69.41% (85) | PE_PGRS family protein |
| M. vanbaalenii PYR-1 | Mvan_0414 | - | 4e-05 | 34.78% (69) | PE domain-containing protein |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_0326|M.gilvum_PYR-GCK MT--LRVVPEGLTAASAAVEALTARMAAAHAAAAPLVTAVLPPAADAVSL
Mvan_0414|M.vanbaalenii_PYR-1 MT--LRVVPEGLTAAGAAVEALTARMAAAHAAAAPVVTAVLPPAADVVSL
MSMEG_0618|M.smegmatis_MC2_155 MT--LRVVPEGLTAASSAVEALTARLAAAHAAAAPMISTVLPPAADAVSL
MAB_0664|M.abscessus_ATCC_1997 MS--LNVVPEGLTAASAAVEALTARLAAVNAAAAPVIGAVMPPAADPVSM
Mb1790c|M.bovis_AF2122/97 MS-FVIAVPETIAAAATDLADLGSTIAGANAAAAANTTSLLAAGADEISA
Rv1759c|M.tuberculosis_H37Rv MS-FVIAVPETIAAAATDLADLGSTIAGANAAAAANTTSLLAAGADEISA
MMAR_0608|M.marinum_M MS-FVITAPEALTAAATDLASLGSTIGAANAAAVAPTTAVLAAGADEVSA
MUL_0570|M.ulcerans_Agy99 MS-FVITAPEALTAAATDLASLGSTIGAANAAAVAPTTAVLAAGADEVSA
MLBr_01183|M.leprae_Br4923 MPLFLNAEPQALTAAANTLEGLSAATVASNAAAAQLTTEIAPPAADDVSI
MAV_1346|M.avium_104 MS-FVTTRPEALLAVASMLEGLGSSMDAQNAAAAAPTTSIAPAAADEVSA
*. : . *: : *.. : * : . :***. : ...** :*
Mflv_0326|M.gilvum_PYR-GCK QTATGLSANGVEHQSIAARGVEELGRSGVGVGDSAASYVSGDAMAATSYL
Mvan_0414|M.vanbaalenii_PYR-1 QAATGFSARAAEHQSVAAQGVEELGRSGIAVGESAASYAGGDAMAASSYL
MSMEG_0618|M.smegmatis_MC2_155 QTAAGFSANGAQQSAVAAQGVEELGRSGVGVGESGVSYATGDAQAAASYL
MAB_0664|M.abscessus_ATCC_1997 QSAALFSAHGLERTGAGARAAYELGRSGVGATEAAASYTVGDIQAAATYL
Mb1790c|M.bovis_AF2122/97 AIAALFGAHGRAYQAASAEAAAFHGRFVQALTTGG---------------
Rv1759c|M.tuberculosis_H37Rv AIAALFGAHGRAYQAASAEAAAFHGRFVQALTTGGGAYAAAEAAAVTPLL
MMAR_0608|M.marinum_M AVAALFDAQGQAYQLLSARAATFHEQFLQALSGGGASYAAAEAAAVSPLL
MUL_0570|M.ulcerans_Agy99 AVAAMFDAQGQAYQLLSARAAAFHEQFLQALSGGGASYAAGEAAAVSPLL
MLBr_01183|M.leprae_Br4923 LLAHFFSGHGRQYQAHASQGATNHQDLIQSLLTSSSAYAGTETAN-----
MAV_1346|M.avium_104 LQAAQFSAYGTWYQQVSAQAKAIHQTLVQNLDTNADSYGATEAANRV---
* :.. . .:.. .
Mflv_0326|M.gilvum_PYR-GCK IARG----------------------------------------------
Mvan_0414|M.vanbaalenii_PYR-1 IARG----------------------------------------------
MSMEG_0618|M.smegmatis_MC2_155 TARGL---------------------------------------------
MAB_0664|M.abscessus_ATCC_1997 PGIA----------------------------------------------
Mb1790c|M.bovis_AF2122/97 ----APMRPPRPPP------------------------------------
Rv1759c|M.tuberculosis_H37Rv NSINAPVLAATGRPLIGNGANGAPGTGANGGDAGWLIGNGGAGGSGAKGA
MMAR_0608|M.marinum_M DAINAPVLAATGRPLIGNGANGAPGTGADGGAAGWLIGNGGAGGSGTP--
MUL_0570|M.ulcerans_Agy99 DAINAPVLADTGRPLIGNGAN--------GGAAGWLIGNGGAGGSGTP--
MLBr_01183|M.leprae_Br4923 -----------------------------HDSL-----------------
MAV_1346|M.avium_104 -NTSAAALQGLAPNVIPNAAPAADPPPAGTTSLGTSIG------------
Mflv_0326|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_0414|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_0618|M.smegmatis_MC2_155 --------------------------------------------------
MAB_0664|M.abscessus_ATCC_1997 --------------------------------------------------
Mb1790c|M.bovis_AF2122/97 --------------------------------------------------
Rv1759c|M.tuberculosis_H37Rv NGGAGGPGGAAGLFGNGGAGGAGGTATANNGIGGAGGAGGSAMLFGAGGA
MMAR_0608|M.marinum_M -----------------------GTASVAGGNGGNGGAGG--LLFGTGGA
MUL_0570|M.ulcerans_Agy99 -----------------------GTASVAGGNGGNGGAGG--LLFGTGGA
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_1346|M.avium_104 ------------------------------------------------WA
Mflv_0326|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_0414|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_0618|M.smegmatis_MC2_155 --------------------------------------------------
MAB_0664|M.abscessus_ATCC_1997 --------------------------------------------------
Mb1790c|M.bovis_AF2122/97 --------------------------------------------------
Rv1759c|M.tuberculosis_H37Rv GGAGGAATSLVGGI-GGTGGTGGNAGMLAGAAGAGGAGGFSFSTAGGAGG
MMAR_0608|M.marinum_M GGAGGTASSLVGAIPGGNGGYGGDGGLLFGRGGAGGAGGFGNNTTGGIGG
MUL_0570|M.ulcerans_Agy99 GGAGGTASSLVGAIPGGNGGYGGDGGLLFGRGGAGGAGGFGNNTTGGIGG
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_1346|M.avium_104 QNVGAAASDFITLGEGQFAPVPGAAGIPNFNPGLTAATTAGPPAPAAPAA
Mflv_0326|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_0414|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_0618|M.smegmatis_MC2_155 --------------------------------------------------
MAB_0664|M.abscessus_ATCC_1997 --------------------------------------------------
Mb1790c|M.bovis_AF2122/97 --------------------------------------------------
Rv1759c|M.tuberculosis_H37Rv AGGAGGLFTTGGVGGAGGQGHTGGAGGAGGAGGLFGAGGMGGAGGFGDHG
MMAR_0608|M.marinum_M LGGAGGLFGAGGDGGVGGFGTFAGNGGDGGTG-LFAAGGDGGAGGS---G
MUL_0570|M.ulcerans_Agy99 LGGAGGLFGAGGDGGVGGFGTFAGNGGDGGTG-LFAAGGDSGAGG-----
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_1346|M.avium_104 AAGAPVLASMGRGPSIGGLSVPPSWAPGGVAP------------------
Mflv_0326|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_0414|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_0618|M.smegmatis_MC2_155 --------------------------------------------------
MAB_0664|M.abscessus_ATCC_1997 --------------------------------------------------
Mb1790c|M.bovis_AF2122/97 --------------------------------------------------
Rv1759c|M.tuberculosis_H37Rv TLGTGGAGGDGGGGGLFGAGGDGGAGGSGLTTGGAAGNGGNAGTLSLGAA
MMAR_0608|M.marinum_M LTQGGDGGIGGAALGLFGAGGAGGTGGEGGLFGGAGGMGGSAGML-----
MUL_0570|M.ulcerans_Agy99 --------------------------------------------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_1346|M.avium_104 --------------------------------------------------
Mflv_0326|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_0414|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_0618|M.smegmatis_MC2_155 --------------------------------------------------
MAB_0664|M.abscessus_ATCC_1997 --------------------------------------------------
Mb1790c|M.bovis_AF2122/97 --------------------------------------------------
Rv1759c|M.tuberculosis_H37Rv GGAGGTGGAGGTVFGGGKGGAGGAGGNAGMLFGSGGGGGTGGFGFAAGGQ
MMAR_0608|M.marinum_M FGNGGDGGAGAAATIGNAAGNGGAGGNAGMLIGAGGAGGNGGFGFSASDG
MUL_0570|M.ulcerans_Agy99 --------------------------------------------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_1346|M.avium_104 --------------------------------------------------
Mflv_0326|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_0414|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_0618|M.smegmatis_MC2_155 --------------------------------------------------
MAB_0664|M.abscessus_ATCC_1997 --------------------------------------------------
Mb1790c|M.bovis_AF2122/97 --------------------------------------------------
Rv1759c|M.tuberculosis_H37Rv GGVGGSAGMLSGSGGSGGAGGSGGPAGTAAGGAGGAGGAPGLIGNGGNGG
MMAR_0608|M.marinum_M GAGGAGGNAGFLYGAGGAGGAGGDSVGGADGGDGGNGGKAGLVGQGGDGG
MUL_0570|M.ulcerans_Agy99 -----------------------DSVGGADGGDGGNGGKAGLVGQGGDGG
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_1346|M.avium_104 ---------------------------------AANATPAQLVGAGFTSA
Mflv_0326|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_0414|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_0618|M.smegmatis_MC2_155 --------------------------------------------------
MAB_0664|M.abscessus_ATCC_1997 --------------------------------------------------
Mb1790c|M.bovis_AF2122/97 --------------------------------------------------
Rv1759c|M.tuberculosis_H37Rv NGGESGGTGGVGGAGGNAVLIGNGGEGGIGALAGKSGFGGFGGLLLGADG
MMAR_0608|M.marinum_M AGGNN-----------------------------NSGFG-----------
MUL_0570|M.ulcerans_Agy99 AGGNN-----------------------------NSGFG-----------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_1346|M.avium_104 APDTAP--------------------------------------------
Mflv_0326|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_0414|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_0618|M.smegmatis_MC2_155 --------------------------------------------------
MAB_0664|M.abscessus_ATCC_1997 --------------------------------------------------
Mb1790c|M.bovis_AF2122/97 --------------------------------------------------
Rv1759c|M.tuberculosis_H37Rv YNAPESTSPWHNLQQDILSFINEPTEALTGRPLIGNGDSGTPGTGDDGGA
MMAR_0608|M.marinum_M --------------------------------------------------
MUL_0570|M.ulcerans_Agy99 --------------------------------------------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_1346|M.avium_104 --------------------------------------------------
Mflv_0326|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_0414|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_0618|M.smegmatis_MC2_155 --------------------------------------------------
MAB_0664|M.abscessus_ATCC_1997 --------------------------------------------------
Mb1790c|M.bovis_AF2122/97 --------------------------------------------------
Rv1759c|M.tuberculosis_H37Rv GGWLFGNGGNGGAGAAGTNGSAGGAGGAGGILFGTGGAGGAGGVGTAGAG
MMAR_0608|M.marinum_M ------------------------------------------------TG
MUL_0570|M.ulcerans_Agy99 ------------------------------------------------TG
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_1346|M.avium_104 ------------------------------------------------VT
Mflv_0326|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_0414|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_0618|M.smegmatis_MC2_155 --------------------------------------------------
MAB_0664|M.abscessus_ATCC_1997 --------------------------------------------------
Mb1790c|M.bovis_AF2122/97 --------------------------------------------------
Rv1759c|M.tuberculosis_H37Rv GAGGAGGSAFLIGSGGTGGVGGAATTTGGVGGAGGNAGLLIGAAGLGGCG
MMAR_0608|M.marinum_M GSGGKGGDAVLIGNGGNGGNAGSGGVGPGIAGAAGIGGLLIGEDGMAGLT
MUL_0570|M.ulcerans_Agy99 GSGGKGGDAVLIGNGGNGGNAGSGGVGPGIAGAAGIGGLLIGEDGMAGLT
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_1346|M.avium_104 AVPGGVPSMATAGRGGYGLGAPRYGVKPTVMPKPAI--------------
Mflv_0326|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_0414|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_0618|M.smegmatis_MC2_155 --------------------------------------------------
MAB_0664|M.abscessus_ATCC_1997 --------------------------------------------------
Mb1790c|M.bovis_AF2122/97 --------------------------------------------------
Rv1759c|M.tuberculosis_H37Rv GGAFTAGVTTGGAGGTGGAAGLFANGGAGGAGGTGSTAGGAGGAGGAGGL
MMAR_0608|M.marinum_M P-------------------------------------------------
MUL_0570|M.ulcerans_Agy99 P-------------------------------------------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_1346|M.avium_104 --------------------------------------------------
Mflv_0326|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_0414|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_0618|M.smegmatis_MC2_155 --------------------------------------------------
MAB_0664|M.abscessus_ATCC_1997 --------------------------------------------------
Mb1790c|M.bovis_AF2122/97 --------------------------------------------------
Rv1759c|M.tuberculosis_H37Rv YAHGGTGGPGGNGGSTGAGGTGGAGGPGGLYGAGGSGGAGGHGGMAGGGG
MMAR_0608|M.marinum_M --------------------------------------------------
MUL_0570|M.ulcerans_Agy99 --------------------------------------------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_1346|M.avium_104 --------------------------------------------------
Mflv_0326|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_0414|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_0618|M.smegmatis_MC2_155 --------------------------------------------------
MAB_0664|M.abscessus_ATCC_1997 --------------------------------------------------
Mb1790c|M.bovis_AF2122/97 --------------------------------------------------
Rv1759c|M.tuberculosis_H37Rv GVGGNAGSLTLNASGGAGGSGGSSLSGKAGAGGAGGSAGLFYGSGGAGGN
MMAR_0608|M.marinum_M --------------------------------------------------
MUL_0570|M.ulcerans_Agy99 --------------------------------------------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_1346|M.avium_104 --------------------------------------------------
Mflv_0326|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_0414|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_0618|M.smegmatis_MC2_155 --------------------------------------------------
MAB_0664|M.abscessus_ATCC_1997 --------------------------------------------------
Mb1790c|M.bovis_AF2122/97 --------------------------------------------------
Rv1759c|M.tuberculosis_H37Rv GGYSLNGTGGDGGTGGAGQITGLRSGFGGAGGAGGASDTGAGGNGGAGGK
MMAR_0608|M.marinum_M --------------------------------------------------
MUL_0570|M.ulcerans_Agy99 --------------------------------------------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_1346|M.avium_104 --------------------------------------------------
Mflv_0326|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_0414|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_0618|M.smegmatis_MC2_155 --------------------------------------------------
MAB_0664|M.abscessus_ATCC_1997 --------------------------------------------------
Mb1790c|M.bovis_AF2122/97 --------------------------------------------------
Rv1759c|M.tuberculosis_H37Rv AGLYGNGGDGGAGGDGATSGKGGAGGNAVVIGNGGNGGNAGKAGGTAGAG
MMAR_0608|M.marinum_M --------------------------------------------------
MUL_0570|M.ulcerans_Agy99 --------------------------------------------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_1346|M.avium_104 --------------------------------------------------
Mflv_0326|M.gilvum_PYR-GCK ----------------
Mvan_0414|M.vanbaalenii_PYR-1 ----------------
MSMEG_0618|M.smegmatis_MC2_155 ----------------
MAB_0664|M.abscessus_ATCC_1997 ----------------
Mb1790c|M.bovis_AF2122/97 ----------------
Rv1759c|M.tuberculosis_H37Rv GAGGLVLGRDGQHGLT
MMAR_0608|M.marinum_M ----------------
MUL_0570|M.ulcerans_Agy99 ----------------
MLBr_01183|M.leprae_Br4923 ----------------
MAV_1346|M.avium_104 ----------------