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MSFVIAAPEVIAAAATDLASLESSIAAANAAAAANTTALLAAGADEVSTAVAALFGAHGQAYQALSAQAQ AFHAQFVQALTSGGGAYAAAEAAATSPLLAPINEFFLANTGRPLIGNGANGAPGTGADGAPGGWLIGNGG AGGSGAAGVNGGAGGNGGAGGLIGNGGAGGAGGRASTGTGGAGGAAGMLFGAAGVGGPGGFAAAFGATGG AGGAGGNGGLFADGGVGGAGGATDAGTGGAGGSGGNGGLFGAGGTGGPGGFGIFGGGAGGDGGSGGLFGA GGTGGSGGTSIINVGGNGGAGGDAGMLSLGAAGGAGGSGGSSPDGGGGAGGIGGDGGTLFGSGGAGGVGG LGFDAGGAGGAGGKAGLLSGAGGAGGAGGGSFAGAGGTGGAGGAPGLVGNAGNGGNGGASANGAGAAGGA GGSGVLIGNGGNGGSGGTGAPAGTAGAGGLGGQLLGRDGFNAPASTPLHTLQQQILNAINEPTQALTGRP LIGNGANGTPGTGADGGAGGWLFGNGGNGGHGATGADGGDGGSGGAGGILSGIGGTGGSGGIGTTGQGGT GGTGGAALLIGSGGTGGSGGFGLDTGGAGGRGGDAGLFLGAAGTGGQAALSQNFIGAGGTAGAGGTGGLF ANGGAGGFGANGGTGGNGLLFGAGGTGGAGTLGADGGAGGHGGLFGAGGTGGAGGSSGGTFGGNGGSGGN AGLLALGASGGAGGSGGSALNVGGTGGVGGNGGSGGSLFGFGGAGGTGGSSGIGSSGGTGGDGGTAGVFG NGGDGGAGGFGTGAGGTGGTGGNAVLIGNGGNGGNGGKAGGTPGAGGTSGLIIGENGLNGL
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0287c | PE_PGRS4 | - | 100% (831) | PE-PGRS family protein |
| M. bovis AF2122 / 97 | Mb0286c | PE_PGRS3 | 0.0 | 73.09% (888) | PE-PGRS family protein |
| M. bovis AF2122 / 97 | Mb0285c | PE_PGRS3a | 0.0 | 70.59% (891) | hypothetical protein Mb0285c |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. gilvum PYR-GCK | Mflv_5091 | - | 1e-156 | 45.68% (821) | triple helix repeat-containing collagen |
| M. tuberculosis H37Rv | Rv0279c | PE_PGRS4 | 0.0 | 97.37% (837) | PE-PGRS family protein |
| M. leprae Br4923 | MLBr_01183 | - | 3e-13 | 39.56% (91) | hypothetical protein MLBr_01183 |
| M. abscessus ATCC 19977 | MAB_4284c | - | 8e-45 | 29.75% (568) | hypothetical protein MAB_4284c |
| M. marinum M | MMAR_1850 | - | 0.0 | 59.25% (881) | PE-PGRS family protein |
| M. avium 104 | MAV_4827 | - | 8e-24 | 45.36% (183) | hypothetical protein MAV_4827 |
| M. smegmatis MC2 155 | MSMEG_0868 | - | 1e-120 | 35.83% (1069) | hypothetical protein MSMEG_0868 |
| M. thermoresistible (build 8) | TH_3810 | - | 1e-40 | 40.48% (294) | PUTATIVE - |
| M. ulcerans Agy99 | MUL_3062 | - | 0.0 | 56.58% (882) | PE-PGRS family protein |
| M. vanbaalenii PYR-1 | Mvan_1264 | - | 1e-151 | 46.68% (799) | triple helix repeat-containing collagen |
CLUSTAL 2.0.9 multiple sequence alignment
Mb0287c|M.bovis_AF2122/97 --------------------------------------------------
Rv0279c|M.tuberculosis_H37Rv --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_1264|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_0868|M.smegmatis_MC2_155 MHERLRERAGGVRKTLSDFAEGAGLKPSDTDDTRSPLRKPKFPAALAPES
TH_3810|M.thermoresistible__bu --------------------------------------------------
MMAR_1850|M.marinum_M --------------------------------------------------
MUL_3062|M.ulcerans_Agy99 --------------------------------------------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 --------------------------------------------------
MAV_4827|M.avium_104 --------------------------------------------------
Mb0287c|M.bovis_AF2122/97 ----------MSFVIAAPEVIAAAATDLASLESSIAAANAAAAANTTALL
Rv0279c|M.tuberculosis_H37Rv ----------MSFVIAAPEVIAAAATDLASLESSIAAANAAAAANTTALL
Mflv_5091|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_1264|M.vanbaalenii_PYR-1 -------------------MMFLAPPGGPGPISAAIQLTSTGSEATEP--
MSMEG_0868|M.smegmatis_MC2_155 PLPDLKPRWERPTTAPDSETPSITQPQGRDTAADPAEQQATSTNTTDQPT
TH_3810|M.thermoresistible__bu --------------------------------------------------
MMAR_1850|M.marinum_M ----------MSFVIAVPDFIGSAATDLTGIGSTLSAANAAAAIPTTEIL
MUL_3062|M.ulcerans_Agy99 ----------MAFVLAVPDMVAEAAADLAGVGSVIDAANTAAAGSTTGIV
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 --------------MSIIDFILNLFRDPVEAASYVADPEAALANAGLSAV
MAV_4827|M.avium_104 --------------MNIVLGVSMAPSSIQMVVLEGEYADGATVEEDAIDV
Mb0287c|M.bovis_AF2122/97 AAGADEVSTAVAALFGAHGQAYQALSAQAQAFHAQFVQALTSGGGAYAAA
Rv0279c|M.tuberculosis_H37Rv AAGADEVSTAVAALFGAHGQAYQALSAQAQAFHAQFVQALTSGGGAYAAA
Mflv_5091|M.gilvum_PYR-GCK --------------------------------------MVTFGGGATPTP
Mvan_1264|M.vanbaalenii_PYR-1 ------------------------------------WYVVSFGGSGAPTP
MSMEG_0868|M.smegmatis_MC2_155 SDSLGAQPTAQVARQVQAPATDPAPAAPSLRPISGLLSVVTLGTTLIPNA
TH_3810|M.thermoresistible__bu --------------------------------------------------
MMAR_1850|M.marinum_M AAAEDEISTAIAALFSGHAQAYQAASAQAAAFGSRFVQALTSGAGAYTS-
MUL_3062|M.ulcerans_Agy99 AAAEDEVSAAIAALFSGHGQAYQQISTRVAEFHAQFERVFAAGVQAYSG-
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 SAAQVGAVMPVVAESVASNYGYQSQWVNTGNPIHDLSGNLQNYYAAQPDG
MAV_4827|M.avium_104 TGADDAATASAPDRVISAILGTREGAADAGLQLSSIGVTWTDQLEAAALR
Mb0287c|M.bovis_AF2122/97 ----------------------------------------EAAATSP---
Rv0279c|M.tuberculosis_H37Rv ----------------------------------------EAAATSP---
Mflv_5091|M.gilvum_PYR-GCK ----------------------------------------TSLGAAAVDL
Mvan_1264|M.vanbaalenii_PYR-1 ----------------------------------------NNLAASLVDL
MSMEG_0868|M.smegmatis_MC2_155 PTEPADMPGVWAVMAWARRQPMYSDPAMRTTVNPQAQLPVPTVASAVLDP
TH_3810|M.thermoresistible__bu --------------------------------------------------
MMAR_1850|M.marinum_M -----------------------------------AEAASAASIADP---
MUL_3062|M.ulcerans_Agy99 -----------------------------------AEAANASFLQDP---
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 ----------------------------------------PSILSPSLLS
MAV_4827|M.avium_104 ----------------------------------------DALAARR---
Mb0287c|M.bovis_AF2122/97 -----------------------------------------LLAPINEFF
Rv0279c|M.tuberculosis_H37Rv -----------------------------------------LLAPINEFF
Mflv_5091|M.gilvum_PYR-GCK S------------------------GTSCG----------LICNGQDGTG
Mvan_1264|M.vanbaalenii_PYR-1 S------------------------GTSCG----------LICNGQDGTG
MSMEG_0868|M.smegmatis_MC2_155 TQIVNWLIYQPLHAAGQQFWVVSPIGSTLGGVINTISGQYLIGNGINGTA
TH_3810|M.thermoresistible__bu --------------------------------------------------
MMAR_1850|M.marinum_M -----------------------------------------LLAAINA--
MUL_3062|M.ulcerans_Agy99 -----------------------------------------LQTALNATN
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 P----------------------------------------RDNDFLSHN
MAV_4827|M.avium_104 -------------------------------------------IDNVMLV
Mb0287c|M.bovis_AF2122/97 LAN---TGRPLIGNGANGAPG-----TGADGAPGGWLIGNGGAGGSGAAG
Rv0279c|M.tuberculosis_H37Rv LAN---TGRPLIGNGTNGAPG-----TGANGGDGGWLIGNGGAGGSGAAG
Mflv_5091|M.gilvum_PYR-GCK QN-----GGILFGNGGSGWNSDVVGMDGGNGGNGGLFGGNGGNGGNGLGG
Mvan_1264|M.vanbaalenii_PYR-1 QN-----GGILFGNGGSGWNSEIAGVSGGNGGNAGLFGGNGGNGGNGLGS
MSMEG_0868|M.smegmatis_MC2_155 DNPNGGTGGLLFGDGGHGYDGSAAGLAGGNGGNAGLFG-NGGNGGVGWAG
TH_3810|M.thermoresistible__bu ------------------------------------------------VD
MMAR_1850|M.marinum_M -PALALTGRPLIGNGANGTPG-----TGADGAAGGWLLGNGGAGGSGAAG
MUL_3062|M.ulcerans_Agy99 KPVQDLTGRPLVGNGANGVPG-----TGANGAAGGWLLGNGGAGGSGAAG
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 DTDFASHNPIASGNQVMSPSGNVDSFNRGPLLDLSFGDLQFGNRDTTAIG
MAV_4827|M.avium_104 SAFLAAAALAQNVGGAMGYERTAVLLVEPDTATLAVVETSDGSIPDVYKQ
Mb0287c|M.bovis_AF2122/97 --VNGGAGGNGGAGGLIGNGGAGGAGGRASTGTGGAG-----GAAGMLFG
Rv0279c|M.tuberculosis_H37Rv --VNGGAGGNGGAGGLIGNGGAGGAGGRASTGTGGAGG--AGGAAGMLFG
Mflv_5091|M.gilvum_PYR-GCK --GNGGNGGNAGAFALFGNGGNGGNGGVGVVGATGAVG--APGVAGATGA
Mvan_1264|M.vanbaalenii_PYR-1 --GDGGNGGDAGLFSLFGRGGNGGNGGVGIAGATGAVG--APGVAGATGA
MSMEG_0868|M.smegmatis_MC2_155 --LDGGNGGSGG--LLMGIGGAGGAGGVGADGTSAHVDGGTGGTGGTGGG
TH_3810|M.thermoresistible__bu --GDGGSGGRTGLFSKLSRGGDGGDGGLG-------------GNGGHGGG
MMAR_1850|M.marinum_M SGQNGGAGGAAGLFGSGGAGGTGGSS---STGNGGAGG--AGGAGGLLLG
MUL_3062|M.ulcerans_Agy99 --QAGGDGGAAGLIGAGGAGGAGGNSPLRNTANGGNGG--TGGAGGLLFG
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 ----DGAVAVGGSNSGPIASGQGSTAVNGDVRDSNIIN----ADHGSNVG
MAV_4827|M.avium_104 QIRAESYGDAAGQLSAMVAGLEKLESLPGG-----------LLLVGSGVD
Mb0287c|M.bovis_AF2122/97 AAGVGGPGGFAAAFGATGGAGGAGGNGGLFADGGVGG-------------
Rv0279c|M.tuberculosis_H37Rv AAGVGGPGGFAAAFGATGGAGGAGGNGGLFADGGVGG-------------
Mflv_5091|M.gilvum_PYR-GCK TGVTSGVVGGNGEDAVGYGATGAAGAAGAAGAAGAAG-------------
Mvan_1264|M.vanbaalenii_PYR-1 TGVTSNVTGGNGADAVGYGATGAAGAAGAAGAAGKAG-------------
MSMEG_0868|M.smegmatis_MC2_155 TGGTGGIGGTGGGLFGLLGHSGSTGAAGAAGNGGDGGNGGFGYVLIAGPN
TH_3810|M.thermoresistible__bu TGIIS--------------------LLSLAGNGGNGG-------------
MMAR_1850|M.marinum_M NAGTGGAGGYSNFLTASGGVGGTGGTGGLFGAGGLGG------------T
MUL_3062|M.ulcerans_Agy99 PGGVGGAGGAS-FLTG--GTGGDGGAGGLFGAGGLGG------------V
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 VDQSQTRVGGDYTNVSGHGSADIDKSVTVVDDHSQRN-------------
MAV_4827|M.avium_104 VAPLKQVLQTTTFLDVSVAEEPETALARGAALAAANAP------------
Mb0287c|M.bovis_AF2122/97 --AGGATDAGTGGAGGSGG--NGGLFGAGGTGGPGG--------------
Rv0279c|M.tuberculosis_H37Rv --AGGATDAGTGGAGGSGG--NGGLFGAGGTGGPGG--------------
Mflv_5091|M.gilvum_PYR-GCK -AVGSAGAAGEAGETGTWG--NAGLPGKAGDAGGAG--------------
Mvan_1264|M.vanbaalenii_PYR-1 -AVGSAGTAGSAGAPGVWG--NAGLPGAAGAAGGAG--------------
MSMEG_0868|M.smegmatis_MC2_155 VTVGSETRGGTGGAGGTGGQSTAAGPGKGGGGGGGGGGAILIGANGGTVD
TH_3810|M.thermoresistible__bu --NGYRTTDNNALDGGHGG-------------------------------
MMAR_1850|M.marinum_M GGASGMDTGGDGGAGGAGG-LLAGLFGSGGGNGGNG--------------
MUL_3062|M.ulcerans_Agy99 GGSG--NVGGNGGAGGAGG-LLAGLVGAGGGDGGSG--------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 -TTNINDSFNTDRSTNIGS-------------------------------
MAV_4827|M.avium_104 LFASSTAALAYAQDPGTGAVDQYSLP------------------------
Mb0287c|M.bovis_AF2122/97 -----------------FGIFGGGAGGDG-----------------GSGG
Rv0279c|M.tuberculosis_H37Rv -----------------FGIFGGGAGGDG-----------------GSGG
Mflv_5091|M.gilvum_PYR-GCK --AVGAAGAAG------TVGTAGATGGTG---------------TGANGG
Mvan_1264|M.vanbaalenii_PYR-1 --AIGTAGVAG------AAGTAGATGGTG---------------VGGNGG
MSMEG_0868|M.smegmatis_MC2_155 GHAIGGNGGNGGNGSTTAAGGNGGTGGTGRVIAEGTGSTAEGTATGGDGG
TH_3810|M.thermoresistible__bu --------------------------------------------NGGNVG
MMAR_1850|M.marinum_M ----------------GFGSVNGGAGGDG----------------GDGGA
MUL_3062|M.ulcerans_Agy99 ----------------GLG-AAGGDGGNG----------------GRAGL
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 -----------------GNTTNTEIGSHN------------------QAN
MAV_4827|M.avium_104 -----------------------------------------------DYL
Mb0287c|M.bovis_AF2122/97 LFGAGGTGGSGGTSIIN-----------VGGNGGAGGDAGMLSLGAAGGA
Rv0279c|M.tuberculosis_H37Rv LFGAGGTGGSGGTSIIN-----------VGGNGGAGGDAGMLSLGAAGGA
Mflv_5091|M.gilvum_PYR-GCK AGGVGGVGGTGAAG--------------AAGGAGGLGETGTT--GGAGGV
Mvan_1264|M.vanbaalenii_PYR-1 AGQAGGIGGTGAAG--------------AAGQAGTAGETGVT--GGVGGI
MSMEG_0868|M.smegmatis_MC2_155 HSTGTGIGGNGGIGSVYAYGNNGAVSGTATGGRGGDGIDGGT--GGAGGM
TH_3810|M.thermoresistible__bu FFSLFNLGG--------------------AGGWGGSGVDG----------
MMAR_1850|M.marinum_M LAGPGGSGGSGAFG------------GTLGGDGGAGGAAGLL--FGPGGS
MUL_3062|M.ulcerans_Agy99 FGGAGGAGGMGATG------------GHSGGDGGAGGDAGLL--FGTGGA
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 IGTSTSAGGSAAVG----------------GNAGLAGNAGLAG-------
MAV_4827|M.avium_104 YVPVDPEPGDDELAYS-----------AVGEEDAESPTVVIEKLFLPEDS
Mb0287c|M.bovis_AF2122/97 GGSGGSSPDGGGGAGGIGGDGGTLFGSGGAGGVG----------------
Rv0279c|M.tuberculosis_H37Rv GGSGGSNPDGGGGAGGIGGDGGTLFGSGGAGGVC----------------
Mflv_5091|M.gilvum_PYR-GCK GGQ--GTAGGTGGVGGIGGAGSTGAVGGVGGKG----IQGGQG-------
Mvan_1264|M.vanbaalenii_PYR-1 GGQ--GTEGGTGGVGGVGGVGATGGAGGVGGKG----IQGGQG-------
MSMEG_0868|M.smegmatis_MC2_155 GEIYSGADGEATGISAGGDGGSATGADSLGGRGGTSWVQAGYGPTTGGKA
TH_3810|M.thermoresistible__bu -------------VDVVGGNP-----------------------------
MMAR_1850|M.marinum_M GGAGGATFSGTGGVGGAGGHAG-LFGDGGAGAVG----------------
MUL_3062|M.ulcerans_Agy99 GGAGGHAFDGDGGAGGAGGNAGLMFSSGGSGGVG----------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 -------NAGLAGNAGLAGNAGLAGNAGLAGNAG----------------
MAV_4827|M.avium_104 EPRRRPVLLVGSGLAVVGISAVLALEIALAIGIR----------------
Mb0287c|M.bovis_AF2122/97 --------GLGFDAGGAGGAGGKAGLLSG---------------------
Rv0279c|M.tuberculosis_H37Rv --------GLGFDAGGAGGAGGKAGLLIG---------------------
Mflv_5091|M.gilvum_PYR-GCK ------LQGGKGGDGGAGGKGGDADSMGS------------------AGA
Mvan_1264|M.vanbaalenii_PYR-1 ------LQGGQGGDGGTGGTGGDATSMGE------------------AGA
MSMEG_0868|M.smegmatis_MC2_155 SGTAKAGHGGKASDGGKGGNGGDALVMAAGATGVATGNTAIGGNGGAASA
TH_3810|M.thermoresistible__bu -------------DGGTPG------------------------------A
MMAR_1850|M.marinum_M --------GFSSVDGGAGGAGGDAGWFGN-------------------GG
MUL_3062|M.ulcerans_Agy99 --------GAGSIDGGAGGAGGDAGWLGG-------------------GG
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 -------------LAGNAGLAGNAGLAGN---------------------
MAV_4827|M.avium_104 ------------TTGTVALQPTPNQHLIVP-------------------T
Mb0287c|M.bovis_AF2122/97 AGGAGGAGGGSFAG-------------------AGGTGGAGGAPG-----
Rv0279c|M.tuberculosis_H37Rv AGGAGGAGGGSFAG-------------------AGGTGGAGGAPG-----
Mflv_5091|M.gilvum_PYR-GCK TGGKGGNGGNGGRGGLFG---------------KGGNAGNGAD-------
Mvan_1264|M.vanbaalenii_PYR-1 TGGKGGNGGNGGRGSLFG---------------RGGNAGNGGN-------
MSMEG_0868|M.smegmatis_MC2_155 NGAVGGNGGFTNIAAIHGSITDSSATSGHGGAAQGGNGGNGGNGWVQAYD
TH_3810|M.thermoresistible__bu HGESHTPGVYTDRQ------------------------------------
MMAR_1850|M.marinum_M IGGAGGAGYFSSGG-------------------VGGGGGTGGV-------
MUL_3062|M.ulcerans_Agy99 AGGAGGFGTISDGG-------------------AGGRGGGGGQ-------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 AGLAGNAGLAGNAG------------------------------------
MAV_4827|M.avium_104 EQAPAPPPVQASAP------------------------------------
Mb0287c|M.bovis_AF2122/97 --------------LVGNAGNGGNGGASANGAGAAGGAGG----------
Rv0279c|M.tuberculosis_H37Rv --------------LVGNAGNGGNGGASANGAGAAGGAGG----------
Mflv_5091|M.gilvum_PYR-GCK ---------------GGTGGAGGAGGTGG--TGGAGGTGG----------
Mvan_1264|M.vanbaalenii_PYR-1 ---------------GGTGGNGGNGGTGG--TGGNGGTGG----------
MSMEG_0868|M.smegmatis_MC2_155 PNGPAGTTIDKGKAAGGNGGDGGFNGTGGA-TGGRGGDGAGASVWKANGQ
TH_3810|M.thermoresistible__bu -------------------GEDGEDGTGTG-IGGRGGNGG----------
MMAR_1850|M.marinum_M --------------LFGNGGAGGNGGTAS--TGGAGGGGG----------
MUL_3062|M.ulcerans_Agy99 --------------LLGNGGAGGAGGQGGN-DGGAGGLGG----------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 --------------LAGNAGLAGNAGLAGN--AGLAGNAG----------
MAV_4827|M.avium_104 ---------------------QPKISVPEPVAAPKPLSPP----------
Mb0287c|M.bovis_AF2122/97 -------SGVLIGNGGNGGSGGTGAPAGTAGAGGLGGQLLGRDGFNAPAS
Rv0279c|M.tuberculosis_H37Rv -------SGVLIGNGGNGGSGGTGAPAGTAGAGGLGGQLLGRDGFNAPAS
Mflv_5091|M.gilvum_PYR-GCK -------TGGTGGIGGAGSTGGTGGTGGTGGTGGTGGTG-GTGGTGGTGG
Mvan_1264|M.vanbaalenii_PYR-1 -------TGGTGGIGGAGSTGGTGGTGGTGGTGGTGGTG-GTGGTGGTGG
MSMEG_0868|M.smegmatis_MC2_155 HSTGQTDTGGNGGRGGDGGTFVNAGANGNGGAGGAGGVSEGEGGTGGHGG
TH_3810|M.thermoresistible__bu ------SSSGTHPMAEDG--------EHVKALDGRPGLD---GGNGSHGG
MMAR_1850|M.marinum_M -------AGVLIGNGGNAGIGGAGVTVGGTGVGGTSGLLLGLDGFNAPAS
MUL_3062|M.ulcerans_Agy99 -------NGVLIGNGGNGGVGGVGETPGGDGGGGISGLLLGADGFNAPAG
MLBr_01183|M.leprae_Br4923 -----------------------------------------MPLFLNAEP
MAB_4284c|M.abscessus_ATCC_199 -------LAGNAGLAGNAGLAGNAGLAGNAGLAGNAGLAGNAAVAGNAAV
MAV_4827|M.avium_104 -------VAAPLPAAPPPAAPPLPEAPPIPAAPPVVPVPVVVPPVPVPVP
Mb0287c|M.bovis_AF2122/97 -TPLHTLQQQILNAINEPTQALTGRPLIGNGANGTPGTGADGGAGG----
Rv0279c|M.tuberculosis_H37Rv -TPLHTLQQQILNAINEPTQALTGRPLIGNGANGTPGTGADGGAGG----
Mflv_5091|M.gilvum_PYR-GCK ---------TGGKGGTGGTGGAGGTG----GDGGTGGTGGTGGTG-----
Mvan_1264|M.vanbaalenii_PYR-1 ---------TGGKGGTGGTGGDGGTG----GTGGTGGTGGTGGTG-----
MSMEG_0868|M.smegmatis_MC2_155 ---------DGGRGGDGALGGNGGTGGVGLGNGGKGGNGGNGGNGGTYVD
TH_3810|M.thermoresistible__bu ---------NGGHGGRGGFLGIGGSG-------GWGGHGGNGGD------
MMAR_1850|M.marinum_M ASPIHALQQQALTAINGPIQTLTGRPLIGNGTPAAAGSGADGAAGG----
MUL_3062|M.ulcerans_Agy99 SSPVHALQQQALAAINAPVQELTGRPLIGNGLPGSAGSGAAGAPGG----
MLBr_01183|M.leprae_Br4923 ---------QALTAAANTLEGLSAAT-----------VASN---------
MAB_4284c|M.abscessus_ATCC_199 AG-------NAAVAGNAAVGGVLNTG----VSGAIGGSSHVGGAIN----
MAV_4827|M.avium_104 VRIPVPDPVSPPQLLAPPRLSVPQPVQPPVRVPQPPSPPQVGGTVP----
Mb0287c|M.bovis_AF2122/97 ----WLFGNGGNGGHG------------ATGADGGDGG------------
Rv0279c|M.tuberculosis_H37Rv ----WLFGNGGNGGHG------------ATGADGGDGG------------
Mflv_5091|M.gilvum_PYR-GCK ----GTGGTGGTGGAG-----------DGTGGTGGTGG----TGGQGGQG
Mvan_1264|M.vanbaalenii_PYR-1 ----GTGGTGGTGGAG-----------DGLGGTGGTGG----TGGFGGQG
MSMEG_0868|M.smegmatis_MC2_155 PSHTGAGGNGGNGGAGRIRVNNGTATGTATGGNGGNGGNGDADGHRGGKG
TH_3810|M.thermoresistible__bu -----TDADGGNGGDG---------------GNGGSAG------------
MMAR_1850|M.marinum_M ----WLLGDGGAGGSAPLFT-------AQDAGAGGAAGLWGTGGTGGAGG
MUL_3062|M.ulcerans_Agy99 ----WLLGDGGAGGSAAATP-------GAAGGAGGAAGLVGAGGAGGAGA
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 ------ESLGGSGSVG---------------GSTAVGG------------
MAV_4827|M.avium_104 ------QSPPQHQTPP---------------GEGTPPK------------
Mb0287c|M.bovis_AF2122/97 ---------------------SGGAGGILSGIGGTGGSG-----------
Rv0279c|M.tuberculosis_H37Rv ---------------------SGGAGGILSGIGGTGGSG-----------
Mflv_5091|M.gilvum_PYR-GCK GQGG-----------------TGGTGGQGG-LGGGGGTG-----------
Mvan_1264|M.vanbaalenii_PYR-1 GQGG-----------------TGGTGGQGG-LGGVGGTG-----------
MSMEG_0868|M.smegmatis_MC2_155 GDGGEALIRATVIGSNASGTATGGDGGNGGTLGATNGTGGAATIVAYNVV
TH_3810|M.thermoresistible__bu ---------------------RGGTGGLRGVFGINGGNG-----------
MMAR_1850|M.marinum_M TSTGGL-------------GGAGGEGGAGGFLAGTGGAG-----------
MUL_3062|M.ulcerans_Agy99 NTGISN-------------PGFGGAGGAGG--AGAGAGG-----------
MLBr_01183|M.leprae_Br4923 ----------------------AAAAQLTTEIAPPAADD-----------
MAB_4284c|M.abscessus_ATCC_199 ----------------------GAHTGVGGGVSTGVGVG-----------
MAV_4827|M.avium_104 ---------------------PDGPGNYGGGHVPTPGAG-----------
. . .
Mb0287c|M.bovis_AF2122/97 -------------GIGTTGQGGTGGTGGAALLIGSG--------GTGGSG
Rv0279c|M.tuberculosis_H37Rv -------------GIGTTGQGGTGGTGGAALLIGSG--------GTGGSG
Mflv_5091|M.gilvum_PYR-GCK ------------GQGGTGGTGGQGGTGGTGGTGGTG--------GTGGAG
Mvan_1264|M.vanbaalenii_PYR-1 ------------GTGGTGGTGGQGGTGGTGGTGGTG--------GTGGAG
MSMEG_0868|M.smegmatis_MC2_155 QANPQASGTATDGHGGSGINGGHGGNGGQGTIEANGPSAVASGIGAGGNG
TH_3810|M.thermoresistible__bu -------------RAGLGGRGXXXXGGGVGAAVRSG--------------
MMAR_1850|M.marinum_M ----GAGGFSPATGTGAGGVGGAGGAGGLFGGGGGG--------GVGGGS
MUL_3062|M.ulcerans_Agy99 ----GVG--------EAGGAGGLLGAG---GTGGGG--------GVAPSL
MLBr_01183|M.leprae_Br4923 --------------VSILLAHFFSGHGRQYQAHASQ--------------
MAB_4284c|M.abscessus_ATCC_199 ------------SHVGGGISESLGGSGSVGGSTAVG--------------
MAV_4827|M.avium_104 --------------GSGGSGGGHVPTPGAGGSGGSG--------------
Mb0287c|M.bovis_AF2122/97 GFGLDTGGAG-GRGGDAGLFLGAAGTGGQAALSQNFIG--AGGTAGAGGT
Rv0279c|M.tuberculosis_H37Rv GFGLDTGGAG-GRGGDAGLFLGAAGTGGQAALSQNFIG--AGGTAGAGGT
Mflv_5091|M.gilvum_PYR-GCK GDGGLGGLGGFGGSGGTGGQGGLGGPGGSTGGAGGAGG--QAGTAGKGGL
Mvan_1264|M.vanbaalenii_PYR-1 GDGGLGGLGGFGGVGGTGGQGGQGGPGGSTGGAGGAGG--QAGVAGKGGL
MSMEG_0868|M.smegmatis_MC2_155 GDGIDGGLGGNGGDGVVNTTANAANPGSATGTATGGDGGKATGTASQGGN
TH_3810|M.thermoresistible__bu -NGVFSGGGGTPSAGFGVPTTIQFPAGSCTSRAVSREG------------
MMAR_1850|M.marinum_M LAG-PGGGGGAGGAG--GPLSGLVGAGGGAGGHGGPG----DTDGGDGGA
MUL_3062|M.ulcerans_Agy99 VDGGTGGAGGAGGAG--GLFGGIFGAGGGDGGAGGFTGG-IDGAGGVGGA
MLBr_01183|M.leprae_Br4923 ------GATNHQDLIQSLLTSSSAYAGTETANHDSL--------------
MAB_4284c|M.abscessus_ATCC_199 -GGAHTGVGGGVSTGVGVGSHVGGGISESLGGSGSVGGSTAVGGGAHTGV
MAV_4827|M.avium_104 --GGHVPTPGTGGPGGTGGSGGGHVPTPGAGTPGGSGG------------
. . .
Mb0287c|M.bovis_AF2122/97 GG-----LFANGGAG---GFGANGGTGGNGLLFGAGGTGG------AGTL
Rv0279c|M.tuberculosis_H37Rv GG-----LFANGGAGGAGGFGANGGTGGNGLLFGAGGTGG------AGTL
Mflv_5091|M.gilvum_PYR-GCK FG----GSGSAGKAGATGAAGASGGKGAQGATGAQGATG------AQGAT
Mvan_1264|M.vanbaalenii_PYR-1 FG----GSGSAGTAGVTGASGASGGKGAQGATGAQGATG------AQGAT
MSMEG_0868|M.smegmatis_MC2_155 GGPSWVQSGYGSTLGGNATGTATAGKGGEASNGGVAGNGGNALVMAAGTT
TH_3810|M.thermoresistible__bu ------------IMPSSRAASARAG-------------------------
MMAR_1850|M.marinum_M GGNGGLLGGAGGAGGTGG-----YSDDAPSSNGGAGGNAG--LLFGNGGH
MUL_3062|M.ulcerans_Agy99 GGNTGLLGGPGGSGGSGGDGIAKLGFNVDGGAGGAGVNGG--FLFGSGGT
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 GG----------GVNTGVGVGSHVGGGISESLGGSGSVGG----------
MAV_4827|M.avium_104 -----------GHLPFPGAGSTPGGSGGGHLPTPGAGTPG----------
Mb0287c|M.bovis_AF2122/97 GADGGAGGHGGLFGAGGTGGAGGSSG----------------GTFGGNGG
Rv0279c|M.tuberculosis_H37Rv GADGGAGGHGGLFGAGGTGGAGGSSG----------------GTFGGNGG
Mflv_5091|M.gilvum_PYR-GCK G-ATGAAGKAGATGAAGAAGAAGSAG-----------TTGAQGSAGTNGA
Mvan_1264|M.vanbaalenii_PYR-1 G-ATGASGAQGSAGSAGSAGVAGSAG-----------TTGAQGSAGTNGA
MSMEG_0868|M.smegmatis_MC2_155 GVATGNTATGGDGGAATTAGATGGAGGFSNIAAIHGAITDSTAISGHGGA
TH_3810|M.thermoresistible__bu --AACASSTSRSRRSFCCSRA-----------------------------
MMAR_1850|M.marinum_M GGSG-----GASRGFAGTGGAGGNAG--------LLFGSGGFGGFGGFGS
MUL_3062|M.ulcerans_Agy99 GGFGGVGGVGTSTGIGGAGGRGGNAG--------LLFSDAGVGGFGGFG-
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 --STAVGGGAHTSAINDALGGSGSVG----------------GSTAVGGG
MAV_4827|M.avium_104 ---GGLGGFGGGHAPAPGGGLGGGGG------------------------
Mb0287c|M.bovis_AF2122/97 SGGNAGLLALGASGGAGGSGGSALN-------VGGTGGVGGNGGSGGSLF
Rv0279c|M.tuberculosis_H37Rv SGGNAGLLALGASGGAGGSGGSALN-------VGGTGGVGGNGGSGGSLF
Mflv_5091|M.gilvum_PYR-GCK -NGANGSQGAAGKAGATGTTGATG--------AAGEDGDAGSGGSG-ING
Mvan_1264|M.vanbaalenii_PYR-1 -NGANGSQGAAGKAGATGTTGATG--------AAGDAGDPGSEAVD-ING
MSMEG_0868|M.smegmatis_MC2_155 GNGGNGGKGADGWVQAYDPAGPVGSKIANSSAVAGNGGDGGVNGTGGASG
TH_3810|M.thermoresistible__bu --------------------------------------------------
MMAR_1850|M.marinum_M GGGSGGNGGNAGLFGSGGDGGAGGF------GVFIDGGSGGSGGSGGPLL
MUL_3062|M.ulcerans_Agy99 -----GTGGNAGWLGSGGSGGAGG-------GSNGDGGAGGTGGSGGQIV
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 AHTSAINESMNSSINASHSSSMNES-------FGSSMGSHGAAGTGFEAQ
MAV_4827|M.avium_104 ---------------------------------HAPAPGGGLGGFG----
Mb0287c|M.bovis_AF2122/97 GFGGAGG-----------TGGSSGIGSSGGTGGDGGTAGVFGNGGDGGAG
Rv0279c|M.tuberculosis_H37Rv GFGGAGG-----------TGGSSGIGSSGGTGGDGGTAGVFGNGGDGGAG
Mflv_5091|M.gilvum_PYR-GCK GAGGAGG-----------AGGEGGEGGDGGKGGAGAE--------GGAGG
Mvan_1264|M.vanbaalenii_PYR-1 GAGGAGG-----------AGGEGGEGGAGGAGGDGSE--------GGAGG
MSMEG_0868|M.smegmatis_MC2_155 GDGGNGGNTSVWKSGGQTADGEHNTGGNGGNGGDGSEPGPGGNGAGGAGG
TH_3810|M.thermoresistible__bu --------------------------------------------------
MMAR_1850|M.marinum_M GTGGSGG-----------AGGECDLGGFG-DGGDGGDGGGAMLIGNGGNG
MUL_3062|M.ulcerans_Agy99 GDGGAGG-----------AGGQGDLLAAGGSGGDGGQGGDAVLIGTGGNG
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 G----------------HAQGHASETAHTTLPGAEHH-------------
MAV_4827|M.avium_104 --------------------GGHSGGGLGGLGGGHK--------------
Mb0287c|M.bovis_AF2122/97 GFGTGAGGTGGTGGNAVLIGNGGNGGNGGKAGGTPGAGGTSGLIIGENGL
Rv0279c|M.tuberculosis_H37Rv GFGADTGGNSSSVPNAVLIGNGGNGGNGGKAGGTPGAGGTSGLIIGENGL
Mflv_5091|M.gilvum_PYR-GCK ----GGGAGGSGAGGAG--GAGGSGGSGG-SGGSGGSGGAAGDSDD----
Mvan_1264|M.vanbaalenii_PYR-1 ----SGGAGGSGTGGAG--GAGGSGGSGG-SGGAGGSGGAAGDSD-----
MSMEG_0868|M.smegmatis_MC2_155 ----NGGTGGTTAGGSGNGGNGGNGGNGG-ADGTPGTAGTTGANNP----
TH_3810|M.thermoresistible__bu --------------------------------------------------
MMAR_1850|M.marinum_M ----GNGAAGATAGTDGKGGAGGTGGTLL-GEDGLNGLT-----------
MUL_3062|M.ulcerans_Agy99 ----GNGASGVLAG---IGGDGGSRGLLL-GEDGVNGEAAPPMTHIVLLG
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 --------------------------------------------------
MAV_4827|M.avium_104 --------------------------------------------------
Mb0287c|M.bovis_AF2122/97 NGL-----
Rv0279c|M.tuberculosis_H37Rv NGL-----
Mflv_5091|M.gilvum_PYR-GCK --------
Mvan_1264|M.vanbaalenii_PYR-1 --------
MSMEG_0868|M.smegmatis_MC2_155 --------
TH_3810|M.thermoresistible__bu --------
MMAR_1850|M.marinum_M --------
MUL_3062|M.ulcerans_Agy99 GDFPAAAS
MLBr_01183|M.leprae_Br4923 --------
MAB_4284c|M.abscessus_ATCC_199 --------
MAV_4827|M.avium_104 --------