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VTPLLNSINAPVLAATGRPLIGNGANGAPGTGANGGDAGWLIGNGGAGGSGAKGANGGAGGPGGAAGLFG NGGAGGAGGTATANNGIGGAGGAGGSAMLFGAGGAGGAGGAATSLVGGIGGTGGTGGNAGMLAGAAGAGG AGGFSFSTAGGAGGAGGAGGLFTTGGVGGAGGQGHTGGAGGAGGAGGLFGAGGMGGAGGFGDHGTLGTGG AGGDGGGGGLFGAGGDGGAGGSGLTTGGAAGNGGNAGTLSLGAAGGAGGTGGAGGTVFGGGKGGAGGAGG NAGMLFGSGGGGGTGGFGFAAGGQGGVGGSAGMLSGSGGSGGAGGSGGPAGTAAGGAGGAGGAPGLIGNG GNGGNGGESGGTGGVGGAGGNAVLIGNGGEGGIGALAGKSGFGGFGGLLLGADGYNAPESTSPWHNLQQD ILSFINEPTEALTGRPLIGNGDSGTPGTGDDGGAGGWLFGNGGNGGAGAAGTNGSAGGAGGAGGILFGTG GAGGAGGVGTAGAGGAGGAGGSAFLIGSGGTGGVGGAATTTGGVGGAGGNAGLLIGAAGLGGCGGGAFTA GVTTGGAGGTGGAAGLFANGGAGGAGGTGSTAGGAGGAGGAGGLYAHGGTGGPGGNGGSTGAGGTGGAGG PGGLYGAGGSGGAGGHGGMAGGGGGVGGNAGSLTLNASGGAGGSGGSSLSGKAGAGGAGGSAGLFYGSGG AGGNGGYSLNGTGGDGGTGGAGQITGLRSGFGGAGGAGGASDTGAGGNGGAGGKAGLYGNGGDGGAGGDG ATSGKGGAGGNAVVIGNGGNGGNAGKAGGTAGAGGAGGLVLGRDGQHGLT
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1789c | wag22b | - | 100% (820) | hypothetical protein Mb1789c |
| M. bovis AF2122 / 97 | Mb0768 | PE_PGRS10 | 0.0 | 68.16% (851) | PE-PGRS family protein |
| M. bovis AF2122 / 97 | Mb0286c | PE_PGRS3 | 0.0 | 65.79% (836) | PE-PGRS family protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. gilvum PYR-GCK | Mflv_5091 | - | 1e-164 | 44.98% (836) | triple helix repeat-containing collagen |
| M. tuberculosis H37Rv | Rv1759c | wag22 | 0.0 | 100.00% (820) | PE-PGRS family protein |
| M. leprae Br4923 | MLBr_01556 | infB | 5e-08 | 40.82% (98) | translation initiation factor IF-2 |
| M. abscessus ATCC 19977 | MAB_4284c | - | 2e-46 | 36.87% (377) | hypothetical protein MAB_4284c |
| M. marinum M | MMAR_0755 | - | 0.0 | 53.88% (915) | PE-PGRS family protein |
| M. avium 104 | MAV_4827 | - | 6e-24 | 44.94% (158) | hypothetical protein MAV_4827 |
| M. smegmatis MC2 155 | MSMEG_0868 | - | 1e-130 | 36.46% (1067) | hypothetical protein MSMEG_0868 |
| M. thermoresistible (build 8) | TH_3810 | - | 1e-41 | 41.14% (299) | PUTATIVE - |
| M. ulcerans Agy99 | MUL_3062 | - | 0.0 | 54.03% (844) | PE-PGRS family protein |
| M. vanbaalenii PYR-1 | Mvan_1264 | - | 1e-163 | 45.01% (822) | triple helix repeat-containing collagen |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_5091|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_1264|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_0868|M.smegmatis_MC2_155 MHERLRERAGGVRKTLSDFAEGAGLKPSDTDDTRSPLRKPKFPAALAPES
Mb1789c|M.bovis_AF2122/97 --------------------------------------------------
Rv1759c|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_0755|M.marinum_M --------------------------------------------------
MUL_3062|M.ulcerans_Agy99 --------------------------------------------------
TH_3810|M.thermoresistible__bu --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 --------------------------------------------------
MAV_4827|M.avium_104 --------------------------------------------------
MLBr_01556|M.leprae_Br4923 --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_1264|M.vanbaalenii_PYR-1 -------------------MMFLAPPGGPGPISAAIQLTSTGSEATEP--
MSMEG_0868|M.smegmatis_MC2_155 PLPDLKPRWERPTTAPDSETPSITQPQGRDTAADPAEQQATSTNTTDQPT
Mb1789c|M.bovis_AF2122/97 --------------------------------------------------
Rv1759c|M.tuberculosis_H37Rv --------MSFVIAVPETIAAAATDLADLGSTIAGANAAAAAN--TTSLL
MMAR_0755|M.marinum_M --------MSYLIATPDLLSAAATDLAGIGNTIGQASYAAAAP--TTAVI
MUL_3062|M.ulcerans_Agy99 --------MAFVLAVPDMVAEAAADLAGVGSVIDAANTAAAGS--TTGIV
TH_3810|M.thermoresistible__bu --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 --------------------------------------------------
MAV_4827|M.avium_104 --------------------------------------------------
MLBr_01556|M.leprae_Br4923 -------------------------MAGKARVHELAKELGVTSKEVLARL
Mflv_5091|M.gilvum_PYR-GCK --------------------------------------MVTFGGGATPTP
Mvan_1264|M.vanbaalenii_PYR-1 ------------------------------------WYVVSFGGSGAPTP
MSMEG_0868|M.smegmatis_MC2_155 SDSLGAQPTAQVARQVQAPATDPAPAAPSLRPISGLLSVVTLGTTLIPNA
Mb1789c|M.bovis_AF2122/97 --------------------------------------------------
Rv1759c|M.tuberculosis_H37Rv AAGADEISAAIAALFGAHGRAYQAASAEAAAFHGRFVQALTTGGGAYAAA
MMAR_0755|M.marinum_M SAAADEISMQIAALFGAHGQSFQAVSSQAALFHDQFVQALTTGASSYASA
MUL_3062|M.ulcerans_Agy99 AAAEDEVSAAIAALFSGHGQAYQQISTRVAEFHAQFERVFAAGVQAYSGA
TH_3810|M.thermoresistible__bu --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 ----------------------------------MSIIDFILNLFRDP--
MAV_4827|M.avium_104 -------------------------------------MNIVLGVSMAPSS
MLBr_01556|M.leprae_Br4923 NEQGEFVKSASSTVEAPVARRLRESFGGIKPAADKGAEQVATKAQAKRLG
Mflv_5091|M.gilvum_PYR-GCK ----------------------------------------TSLGAAAVDL
Mvan_1264|M.vanbaalenii_PYR-1 ----------------------------------------NNLAASLVDL
MSMEG_0868|M.smegmatis_MC2_155 PTEPADMPGVWAVMAWARRQPMYSDPAMRTTVNPQAQLPVPTVASAVLDP
Mb1789c|M.bovis_AF2122/97 -----------------------------------MTPLLNSINAPVLAA
Rv1759c|M.tuberculosis_H37Rv ------------------------EAA-------AVTPLLNSINAPVLAA
MMAR_0755|M.marinum_M ------------------------EAA-------SQN-LLNLVNAPTQAL
MUL_3062|M.ulcerans_Agy99 ------------------------EAANASFLQDPLQTALNATNKPVQDL
TH_3810|M.thermoresistible__bu --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 ------------------------------------VEAASYVADPEAAL
MAV_4827|M.avium_104 ------------------------------------------IQMVVLEG
MLBr_01556|M.leprae_Br4923 ---------------------------------ESLDQTLDRALDKAVAG
Mflv_5091|M.gilvum_PYR-GCK S------------------------GTSCG----------LICNGQDGTG
Mvan_1264|M.vanbaalenii_PYR-1 S------------------------GTSCG----------LICNGQDGTG
MSMEG_0868|M.smegmatis_MC2_155 TQIVNWLIYQPLHAAGQQFWVVSPIGSTLGGVINTISGQYLIGNGINGTA
Mb1789c|M.bovis_AF2122/97 TG-----------------------RPLIGNG----------ANGAPGTG
Rv1759c|M.tuberculosis_H37Rv TG-----------------------RPLIGNG----------ANGAPGTG
MMAR_0755|M.marinum_M LN-----------------------RPLIGNG----------ANGAAGTG
MUL_3062|M.ulcerans_Agy99 TG-----------------------RPLVGNG----------ANGVPGTG
TH_3810|M.thermoresistible__bu --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 AN------------------------------------------------
MAV_4827|M.avium_104 EY------------------------------------------------
MLBr_01556|M.leprae_Br4923 NG----------------------------------------ATTAAPVQ
Mflv_5091|M.gilvum_PYR-GCK QN-----GGILFGNGGSGWNS--DVVGMDGGNGGNGGLFGGNGGNGGNGL
Mvan_1264|M.vanbaalenii_PYR-1 QN-----GGILFGNGGSGWNS--EIAGVSGGNGGNAGLFGGNGGNGGNGL
MSMEG_0868|M.smegmatis_MC2_155 DNPNGGTGGLLFGDGGHGYDG--SAAGLAGGNGGNAGLFG-NGGNGGVGW
Mb1789c|M.bovis_AF2122/97 AN--GGDAGWLIGNGGAGGSGAKGANGGAGGPGGAAGLFG-NGGAGGAGG
Rv1759c|M.tuberculosis_H37Rv AN--GGDAGWLIGNGGAGGSGAKGANGGAGGPGGAAGLFG-NGGAGGAGG
MMAR_0755|M.marinum_M AS--GGDGGILIGNGGAGGSGATGLTGGAGGNGGAAGLLAGTAGAGGSGG
MUL_3062|M.ulcerans_Agy99 AN--GAAGGWLLGNGGAGGS---GAAGQAGGDGGAAGLIG----------
TH_3810|M.thermoresistible__bu ----------VDGDGGSGGRTGLFSKLSRGGDGGDGGLGG----------
MAB_4284c|M.abscessus_ATCC_199 ------AGLSAVSAAQVGAVMPVVAESVASNYGYQSQWVNTGNPIHDLSG
MAV_4827|M.avium_104 ------ADGATVEEDAIDVTGADDAATASAPDRVISAILG----------
MLBr_01556|M.leprae_Br4923 VDHSAAVVPIVAGEGPSTAHREELAPPAGQPSEQPGVPLPGQQGTPAAPH
.
Mflv_5091|M.gilvum_PYR-GCK GGGN----GGNGGNAGAFALFGNGGNG-----------GNGGVGVVGATG
Mvan_1264|M.vanbaalenii_PYR-1 GSGD----GGNGGDAGLFSLFGRGGNG-----------GNGGVGIAGATG
MSMEG_0868|M.smegmatis_MC2_155 AGLD----GGNGGSGG--LLMGIGGAG-----------GAGGVGADGTSA
Mb1789c|M.bovis_AF2122/97 TATANNGIGGAGGAGGSAMLFGAGGAGGAGGAATSLVGGIGGTGGTGGNA
Rv1759c|M.tuberculosis_H37Rv TATANNGIGGAGGAGGSAMLFGAGGAGGAGGAATSLVGGIGGTGGTGGNA
MMAR_0755|M.marinum_M LGAA--GAGGAGGQGGTGGLFSAGGAGGTGG-----VGASGGTGGAGGLG
MUL_3062|M.ulcerans_Agy99 -------AGGAGGAGGNSPLRNT---------------ANGGNGGTGGAG
TH_3810|M.thermoresistible__bu -------NGGHGGGTGIISLLSLAGNG-----------GNGGNGYR----
MAB_4284c|M.abscessus_ATCC_199 NLQNYYAAQPDGPSILSPSLLSPRDND----------FLSHNDTDFASHN
MAV_4827|M.avium_104 ------TREGAADAGLQLSSIGVTWTD--------QLEAAALRDALAARR
MLBr_01556|M.leprae_Br4923 PGHPGMPTGPHPGPAPKPGGRPPRVGN----------NPFSSAQSVARPI
Mflv_5091|M.gilvum_PYR-GCK AVG--APGVAGATGATGVTSGVVGGNGEDAVGYGATGAAGAAGAAGAAGA
Mvan_1264|M.vanbaalenii_PYR-1 AVG--APGVAGATGATGVTSNVTGGNGADAVGYGATGAAGAAGAAGAAGK
MSMEG_0868|M.smegmatis_MC2_155 HVDGGTGGTGGTGGGTGGTGGIGGTGGGLFGLLGHSGSTGAAGAAGNGGD
Mb1789c|M.bovis_AF2122/97 GMLAGAAGAGGAGGFSFSTAGGAGGAGGAGGLFTTGGVGGAGGQGHTGG-
Rv1759c|M.tuberculosis_H37Rv GMLAGAAGAGGAGGFSFSTAGGAGGAGGAGGLFTTGGVGGAGGQGHTGG-
MMAR_0755|M.marinum_M --LFGAGGAGGAGGMANATVGGTGGAGGASLLFGNGGAGGLGGGGATAGG
MUL_3062|M.ulcerans_Agy99 GLLFGPGGVGGAGGASFLTGG-TGGDGGAGGLFGAGGLGGVGGSGNVGG-
TH_3810|M.thermoresistible__bu ------------TTDNNALDGGHGGNGGNVGFFSLFNLGGAGG-------
MAB_4284c|M.abscessus_ATCC_199 PIASGNQVMSPSGNVDSFNRGPLLDLSFGDLQFGNRDTTAIGDGAVAVGG
MAV_4827|M.avium_104 IDNVMLVSAFLAAAALAQNVGGAMGYERTAVLLVEPDTATLAVVETSDGS
MLBr_01556|M.leprae_Br4923 PRPPAPRPSASPSSMSPRPGGAVGGGGPRPPRTGVPRPGGGRPGAPVGGR
.
Mflv_5091|M.gilvum_PYR-GCK AG--------------AVGSAGAAGEAGETGTWG--NAGLPGKAGDAGGA
Mvan_1264|M.vanbaalenii_PYR-1 AG--------------AVGSAGTAGSAGAPGVWG--NAGLPGAAGAAGGA
MSMEG_0868|M.smegmatis_MC2_155 GGNGGFGYVLIAGPNVTVGSETRGGTGGAGGTGGQSTAAGPGKGGGGGGG
Mb1789c|M.bovis_AF2122/97 AGGAGG----------AGGLFGAGGMGGAGGFGDHGTLGTGGAGGDGGGG
Rv1759c|M.tuberculosis_H37Rv AGGAGG----------AGGLFGAGGMGGAGGFGDHGTLGTGGAGGDGGGG
MMAR_0755|M.marinum_M AGGQGGD---------AGTFYGDGGVGGAGGAGGNIPGSSGGAGGAGGNA
MUL_3062|M.ulcerans_Agy99 NGGAGGA---------GGLLAGLVGAGGGDG-GSGGLGAAGGDGGNGGRA
TH_3810|M.thermoresistible__bu --------------------WGGSGVDGVDVVGGNPDGGTPG--------
MAB_4284c|M.abscessus_ATCC_199 SN--------------SGPIASGQGSTAVNGDVRDSNIINADHGSNVGVD
MAV_4827|M.avium_104 IP---------------DVYKQQIRAESYGDAAGQLSAMVAGLEKLESLP
MLBr_01556|M.leprae_Br4923 SD-------------AGGGNYRGGGVGALPGGGSGGFRGRPGGGGHGGGG
. .
Mflv_5091|M.gilvum_PYR-GCK G----------------AVGAAGAAG-------TVGTAGATGGTG-----
Mvan_1264|M.vanbaalenii_PYR-1 G----------------AIGTAGVAG-------AAGTAGATGGTG-----
MSMEG_0868|M.smegmatis_MC2_155 GGGAILIGANGGTVDGHAIGGNGGNGGNGST-TAAGGNGGTGGTGRVIAE
Mb1789c|M.bovis_AF2122/97 G----------------LFG-AGGDGGAGGSGLTTGGAAGNGGNAGTLS-
Rv1759c|M.tuberculosis_H37Rv G----------------LFG-AGGDGGAGGSGLTTGGAAGNGGNAGTLS-
MMAR_0755|M.marinum_M G----------------LFHGDGGAGGTGGVATSAGGAGGAGGNAADLVG
MUL_3062|M.ulcerans_Agy99 G----------------LFGGAGGAGGMGATGGHSGGDGGAGGDAGLLF-
TH_3810|M.thermoresistible__bu --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 Q-------------------------------------------------
MAV_4827|M.avium_104 G-------------------------------------------------
MLBr_01556|M.leprae_Br4923 R--------------------PGQRGGAAGAFGRPGGAPRRGRKSKRQK-
Mflv_5091|M.gilvum_PYR-GCK ----------TGANGGAGGVGGVGGTGAAG---------------AAGGA
Mvan_1264|M.vanbaalenii_PYR-1 ----------VGGNGGAGQAGGIGGTGAAG---------------AAGQA
MSMEG_0868|M.smegmatis_MC2_155 GTGSTAEGTATGGDGGHSTGTGIGGNGGIGS-VYAYGNNGAVSGTATGGR
Mb1789c|M.bovis_AF2122/97 ---LGAAG-------GAGGTGGAGGTVFGGG-----------KGGAGGAG
Rv1759c|M.tuberculosis_H37Rv ---LGAAG-------GAGGTGGAGGTVFGGG-----------KGGAGGAG
MMAR_0755|M.marinum_M TGGVGGAGGTSFDAGGAGGIGGSAGALFGAGGAGGAGGFGQVSGGAGGAG
MUL_3062|M.ulcerans_Agy99 ---------------GTGGAGGAGGHAFDGD------------GGAGGAG
TH_3810|M.thermoresistible__bu ---------------------------------------------AHGES
MAB_4284c|M.abscessus_ATCC_199 ---------------SQTRVGGDYTNVSGHG--------------SADID
MAV_4827|M.avium_104 ------------------GLLLVGSGVDVAP--------------LKQVL
MLBr_01556|M.leprae_Br4923 ----------------RQEYDSMQAPVVGGVR------------LPHGNG
Mflv_5091|M.gilvum_PYR-GCK GGLGETGTTGGAGGVGGQ--GTAGGTGGVGGIGGAGSTGAVGGVGGKG--
Mvan_1264|M.vanbaalenii_PYR-1 GTAGETGVTGGVGGIGGQ--GTEGGTGGVGGVGGVGATGGAGGVGGKG--
MSMEG_0868|M.smegmatis_MC2_155 GGDGIDGGTGGAGGMGEIYSGADGEATGISAGGDGGSATGADSLGGRGGT
Mb1789c|M.bovis_AF2122/97 GNAGMLFGSGGGGGTGGFG-FAAGGQGGVG--GSAGMLSGSGGSGG----
Rv1759c|M.tuberculosis_H37Rv GNAGMLFGSGGGGGTGGFG-FAAGGQGGVG--GSAGMLSGSGGSGG----
MMAR_0755|M.marinum_M GNSGMVYGDGGAGGAGGIGGAAAGGKGGDG--GDAATLFGSGGTGGHGAA
MUL_3062|M.ulcerans_Agy99 GNAGLMFSSGGSGGVGGAG-SIDGGAGGAG--GDAGWLGG-GGAGG----
TH_3810|M.thermoresistible__bu HTPGVYTDRQGEDGEDGTG-------TGIG--------------------
MAB_4284c|M.abscessus_ATCC_199 KSVTVVDDHSQRNTTNINDSFNTDRSTNIGSGNTTNTEIGSHNQANIG--
MAV_4827|M.avium_104 QTTTFLDVSVAEEPETALARGAALAAANAPLFASSTAALAYAQDPG----
MLBr_01556|M.leprae_Br4923 ETIRLARGASLSDFAEKIDANPAALVQALFNLGEMVTATQSVGDETLELL
Mflv_5091|M.gilvum_PYR-GCK --IQGGQG-------------LQGGKGGDGGAGGKGG-------------
Mvan_1264|M.vanbaalenii_PYR-1 --IQGGQG-------------LQGGQGGDGGTGGTGG-------------
MSMEG_0868|M.smegmatis_MC2_155 SWVQAGYGPTTGGKASGTAKAGHGGKASDGGKGGNGG-------------
Mb1789c|M.bovis_AF2122/97 ---AGGSG------------GPAGTAAG--GAGGAGG-------------
Rv1759c|M.tuberculosis_H37Rv ---AGGSG------------GPAGTAAG--GAGGAGG-------------
MMAR_0755|M.marinum_M GAVAGGDG------------GRGGTGGGLAGSGGTGGNGAVGTVSGVGGD
MUL_3062|M.ulcerans_Agy99 ---AGGFG------------TISDGGAG--GRGGGGG-------------
TH_3810|M.thermoresistible__bu ------------------------------GRGGNGG-------------
MAB_4284c|M.abscessus_ATCC_199 ---------------------TSTSAGGSAAVGGNAG-------------
MAV_4827|M.avium_104 -----------------------------TGAVDQYS-------------
MLBr_01556|M.leprae_Br4923 GSEMNYNVQVVSPEDEDRELLEPFDLTYGEDQGDEDE-------------
.
Mflv_5091|M.gilvum_PYR-GCK ---DADSMGS------------------AGATGGKGGNGGNGGRGGLFG-
Mvan_1264|M.vanbaalenii_PYR-1 ---DATSMGE------------------AGATGGKGGNGGNGGRGSLFG-
MSMEG_0868|M.smegmatis_MC2_155 ---DALVMAAGATGVATGNTAIGGNGGAASANGAVGGNGGFTNIAAIHGS
Mb1789c|M.bovis_AF2122/97 ---APGLIGNGGNG----------GNGGES--GGTGGVGGAGGNAVLIG-
Rv1759c|M.tuberculosis_H37Rv ---APGLIGNGGNG----------GNGGES--GGTGGVGGAGGNAVLIG-
MMAR_0755|M.marinum_M GGNAAGLFGDGGTG----------GNGGLATAGGAGGDGGAGGKAALIG-
MUL_3062|M.ulcerans_Agy99 -----QLLGNGGAG----------GAGGQG--GNDGGAGGLGGNGVLIG-
TH_3810|M.thermoresistible__bu ---------------------------------SSSGTHPMAEDG-----
MAB_4284c|M.abscessus_ATCC_199 ----------------------------LAGNAGLAGNAGLAGNAGLAG-
MAV_4827|M.avium_104 ----------------------------LPDYLYVPVDPEPGDDELAYS-
MLBr_01556|M.leprae_Br4923 -------------------------LQVRPPVVTVMGHVDHGKTRLLDT-
Mflv_5091|M.gilvum_PYR-GCK --------------KGGNAGNGAD----------------------GGTG
Mvan_1264|M.vanbaalenii_PYR-1 --------------RGGNAGNGGN----------------------GGTG
MSMEG_0868|M.smegmatis_MC2_155 ITDSSATSGHGGAAQGGNGGNGGNGWVQAYDPNGPAGTTIDKGKAAGGNG
Mb1789c|M.bovis_AF2122/97 --------------NGGEGGIG----------------------ALAGKS
Rv1759c|M.tuberculosis_H37Rv --------------NGGEGGIG----------------------ALAGKS
MMAR_0755|M.marinum_M --------------SGGNGGAGGS--------------------GTVDPG
MUL_3062|M.ulcerans_Agy99 --------------NGGNGGVGG---------------------VGETPG
TH_3810|M.thermoresistible__bu --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 --------------NAGLAGN-------------------------AGLA
MAV_4827|M.avium_104 --------------------------------------------AVGEED
MLBr_01556|M.leprae_Br4923 --------------------------------------------IRKANV
Mflv_5091|M.gilvum_PYR-GCK GAGGAGGTGG-TGGAG-------------GTGG-----------------
Mvan_1264|M.vanbaalenii_PYR-1 GNGGNGGTGG-TGGNG-------------GTGG-----------------
MSMEG_0868|M.smegmatis_MC2_155 GDGGFNGTGGATGGRG-------------GDGAGASVWKANGQHSTGQTD
Mb1789c|M.bovis_AF2122/97 GFGGFGG--LLLGADGYN-----------APESTSP-WHNLQQDILSFIN
Rv1759c|M.tuberculosis_H37Rv GFGGFGG--LLLGADGYN-----------APESTSP-WHNLQQDILSFIN
MMAR_0755|M.marinum_M GNGGRGGDAQLFGTGGNGGNPGLGVPAGTAGEAGAPGLATSNQALLDVIN
MUL_3062|M.ulcerans_Agy99 GDGGGGISGLLLGADGFN-----------APAGSSP-VHALQQQALAAIN
TH_3810|M.thermoresistible__bu --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 GNAGLAGNAGLAGNAG----------------------------------
MAV_4827|M.avium_104 AESPTVVIEKLFLP-----------------------------------E
MLBr_01556|M.leprae_Br4923 REAEAGGITQHIGAYQVG------------------VDLDGSERLITFID
Mflv_5091|M.gilvum_PYR-GCK TGGTGGIGGAGSTGGTGGTGGTGGTGGTGGTG-GTGGTGGTGGTGGKGGT
Mvan_1264|M.vanbaalenii_PYR-1 TGGTGGIGGAGSTGGTGGTGGTGGTGGTGGTG-GTGGTGGTGGTGGKGGT
MSMEG_0868|M.smegmatis_MC2_155 TGGNGGRGGDGGTFVNAGANGNGGAGGAGGVSEGEGGTGGHGGDGGRGGD
Mb1789c|M.bovis_AF2122/97 EPTEALTGRPLIGNGDSGTPGTGDDGGAGGWLFGNGGNGGAGAAG---TN
Rv1759c|M.tuberculosis_H37Rv EPTEALTGRPLIGNGDSGTPGTGDDGGAGGWLFGNGGNGGAGAAG---TN
MMAR_0755|M.marinum_M APTQALLDRPLIGNGANGAAGTGANGGDGGILFGNGGAGGSGAVNGL-GT
MUL_3062|M.ulcerans_Agy99 APVQELTGRPLIGNGLPGSAGSGAAGAPGGWLLGDGGAGGSAAAT----P
TH_3810|M.thermoresistible__bu EHVKALDGRPGLDGGNGSHGGNGGHGGRGGFL-GIGGSGG----------
MAB_4284c|M.abscessus_ATCC_199 LAGNAGLAGNAGLAGNAGLAGNAGLAGNAGLAGNAGLAGNAGLAGNAGLA
MAV_4827|M.avium_104 DSEPRRRPVLLVGSGLAVVGISAVLALEIALAIGIRTTGTVALQPTPNQH
MLBr_01556|M.leprae_Br4923 TPGHEAFTAMRARGAKATDIAILVVAADDGVMPQTVEAINHAQAADVPIV
. .
Mflv_5091|M.gilvum_PYR-GCK GGTGGAGGTG----GDGGTGGTGGTGGTG---------GTGGTGGTGGAG
Mvan_1264|M.vanbaalenii_PYR-1 GGTGGDGGTG----GTGGTGGTGGTGGTG---------GTGGTGGTGGAG
MSMEG_0868|M.smegmatis_MC2_155 GALGGNGGTGGVGLGNGGKGGNGGNGGNGGTYVDPSHTGAGGNGGNGGAG
Mb1789c|M.bovis_AF2122/97 GSAGGAGGAGGILFGTGGAGGAGGVGTAG----------AGGAGGAGGSA
Rv1759c|M.tuberculosis_H37Rv GSAGGAGGAGGILFGTGGAGGAGGVGTAG----------AGGAGGAGGSA
MMAR_0755|M.marinum_M GQAGGNGGAAGLLSGGAGVGGTGGIG-AV----------LGGAGGTGGMA
MUL_3062|M.ulcerans_Agy99 GAAGGAGGAAG-LVGAGGAGGAGANTGIS----------NPGFGGAG---
TH_3810|M.thermoresistible__bu ---------------WGGHGGNGGDTDAD---------------------
MAB_4284c|M.abscessus_ATCC_199 GNAGLAGNAG--LAGNAGLAGNAGLAGNA---------------------
MAV_4827|M.avium_104 LIVPTEQAPAPPPVQASAPQPKISVPEPV---------------------
MLBr_01556|M.leprae_Br4923 VAVNKIDKEGADPAKIRGQLTEYGLVAEDFG---------GDTMFIDIS-
. .
Mflv_5091|M.gilvum_PYR-GCK -----------DGTGGTGGTGG------TGGQG-----GQGGQGG-----
Mvan_1264|M.vanbaalenii_PYR-1 -----------DGLGGTGGTGG------TGGFG-----GQGGQGG-----
MSMEG_0868|M.smegmatis_MC2_155 RIRVNNGTATGTATGGNGGNGGNGDA--DGHRG-----GKGGDGGEALIR
Mb1789c|M.bovis_AF2122/97 FL---------IGSGGTGGVGGAATT--TGGVG-----GAGGNAG-----
Rv1759c|M.tuberculosis_H37Rv FL---------IGSGGTGGVGGAATT--TGGVG-----GAGGNAG-----
MMAR_0755|M.marinum_M GL---------FGAGGAGGEGGGGQSGGAGGAGGVGLFGAGGNGGTG---
MUL_3062|M.ulcerans_Agy99 ------------GAGGAGAGAG-------GGVG-----EAGGAGG-----
TH_3810|M.thermoresistible__bu --------------GGNGGDGG-----------------NGGSAG-----
MAB_4284c|M.abscessus_ATCC_199 ------------AVAGNAAVAG-----------------NAAVAG-----
MAV_4827|M.avium_104 --------------AAPKPLSP-------PVAAPLP--------------
MLBr_01556|M.leprae_Br4923 ------------AKVGTNIEALLEAVLLTADAALDLRANSGMEAQG----
. .
Mflv_5091|M.gilvum_PYR-GCK ------------TGGTG-----------GQGG-LGGGGGTG---------
Mvan_1264|M.vanbaalenii_PYR-1 ------------TGGTG-----------GQGG-LGGVGGTG---------
MSMEG_0868|M.smegmatis_MC2_155 ATVIGSNASGTATGGDG-----------GNGGTLGATNGTGGAATIVAYN
Mb1789c|M.bovis_AF2122/97 ----------LLIGAAG----------LGGCGGGAFTAGVT---------
Rv1759c|M.tuberculosis_H37Rv ----------LLIGAAG----------LGGCGGGAFTAGVT---------
MMAR_0755|M.marinum_M -------GFSLVTGGAGGAGGASLLSGNGGAGGAGGIGGTG---------
MUL_3062|M.ulcerans_Agy99 -----------LLGAGG---------TGGGGGVAPSLVDGG---------
TH_3810|M.thermoresistible__bu --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 ------------------------------NAAVGGVLNTG---------
MAV_4827|M.avium_104 ------------------------------AAPPPAAPPLP---------
MLBr_01556|M.leprae_Br4923 ----------VAIEAHLD---------RGRGPVATVLVQRG---------
Mflv_5091|M.gilvum_PYR-GCK --------------GQGGTGGTGGQGG-TGGTGGTGGTG--------GTG
Mvan_1264|M.vanbaalenii_PYR-1 --------------GTGGTGGTGGQGG-TGGTGGTGGTG--------GTG
MSMEG_0868|M.smegmatis_MC2_155 VVQANPQASGTATDGHGGSGINGGHGG-NGGQGTIEANGPSAVASGIGAG
Mb1789c|M.bovis_AF2122/97 ------------TGGAGGTGGAAGLFA-NGGAGGAGGTG-------STAG
Rv1759c|M.tuberculosis_H37Rv ------------TGGAGGTGGAAGLFA-NGGAGGAGGTG-------STAG
MMAR_0755|M.marinum_M ------------AGGAGGDGGAAGAFSGNGGAGGAGGIAPA-----GTEG
MUL_3062|M.ulcerans_Agy99 ------------TGGAGGAGGAGGLFGGIFGAG----------------G
TH_3810|M.thermoresistible__bu ---------------RGGTGGLRGVFGINGGNG---------------RA
MAB_4284c|M.abscessus_ATCC_199 -----------VSGAIGGSSHVGGAINESLGGSG-------------SVG
MAV_4827|M.avium_104 --------------EAPPIPAAPPVVPVPVVVPPVPVPVP--------VR
MLBr_01556|M.leprae_Br4923 ------------TLRIGDSVVAGDAYGRVRRMVDEHGVD--------IEA
Mflv_5091|M.gilvum_PYR-GCK GAGGDGG-LGGLGGFGGSGGTGGQGGLGGPGGSTGGAGGAGG--QAGTAG
Mvan_1264|M.vanbaalenii_PYR-1 GAGGDGG-LGGLGGFGGVGGTGGQGGQGGPGGSTGGAGGAGG--QAGVAG
MSMEG_0868|M.smegmatis_MC2_155 GNGGDGI-DGGLGGNGGDGVVNTTANAANPGSATGTATGGDGGKATGTAS
Mb1789c|M.bovis_AF2122/97 GAGGAGG-AGGLYAHGGTGGPGGNGGSTG-AGGTGGAGGPGGLYGAGGSG
Rv1759c|M.tuberculosis_H37Rv GAGGAGG-AGGLYAHGGTGGPGGNGGSTG-AGGTGGAGGPGGLYGAGGSG
MMAR_0755|M.marinum_M GAGGAGGNAGVFSGTGGAGGAGGAGQTVGGAGGTG--GGAATLFGAGGAG
MUL_3062|M.ulcerans_Agy99 GDGGAGGFTGGIDGAGGVGGAGGNTGLLGGPGGSG---------GSGGDG
TH_3810|M.thermoresistible__bu GLGGRGX----XXXGGGVG--------------------------AAVRS
MAB_4284c|M.abscessus_ATCC_199 GSTAVGG--GAHTGVGGGVSTGVGVGSHVGGGISESLGGSGSVGGSTAVG
MAV_4827|M.avium_104 IPVPDPVSPPQLLAPPRLSVPQPVQPPVRVPQPPSPPQVGGTVPQSPPQH
MLBr_01556|M.leprae_Br4923 ALPSSPVQVIGFTSVPGAGDNFLVVDEDRIARQIADRRSARKRNALAARS
Mflv_5091|M.gilvum_PYR-GCK KGGLFG----GSGSAGKAGATGAAGASGGKGAQGATGAQGATG------A
Mvan_1264|M.vanbaalenii_PYR-1 KGGLFG----GSGSAGTAGVTGASGASGGKGAQGATGAQGATG------A
MSMEG_0868|M.smegmatis_MC2_155 QGGNGGPSWVQSGYGSTLGGNATGTATAGKGGEASNGGVAGNGGNALVMA
Mb1789c|M.bovis_AF2122/97 GAGGHG--------GMAGGGGGVGGNAGSLTLN-ASGGAGGSG------G
Rv1759c|M.tuberculosis_H37Rv GAGGHG--------GMAGGGGGVGGNAGSLTLN-ASGGAGGSG------G
MMAR_0755|M.marinum_M GAGAIG--------LDTGGAGGAGGSAGALSGTGGAGGAGGIG------V
MUL_3062|M.ulcerans_Agy99 IAKLGF--------NVDGGAGGAGVNGGFLFGSGGTGGFGGVGG-----V
TH_3810|M.thermoresistible__bu GNGVFS-----------GGGGTPSAGFGVPTTIQFPAGSCTSR------A
MAB_4284c|M.abscessus_ATCC_199 GGAHTG----------VGGGVSTGVGVGSHVGGGISESLGGSG------S
MAV_4827|M.avium_104 QTPPGE--------GTPPKPDGPGNYGGGHVPTPGAGGSGGSG-------
MLBr_01556|M.leprae_Br4923 RKRISLEDLDSALKETSQLNLILKGDNAGTVEALEEALMGIQVDD----E
.
Mflv_5091|M.gilvum_PYR-GCK QGATG-ATGAAGKAGATGAAGAAGAAGSAG-----------TTGAQGSAG
Mvan_1264|M.vanbaalenii_PYR-1 QGATG-ATGASGAQGSAGSAGSAGVAGSAG-----------TTGAQGSAG
MSMEG_0868|M.smegmatis_MC2_155 AGTTGVATGNTATGGDGGAATTAGATGGAGGFSNIAAIHGAITDSTAISG
Mb1789c|M.bovis_AF2122/97 SSLSG-KAGAGGAGGSAGLFYGSGGAGGNGG--------------YSLNG
Rv1759c|M.tuberculosis_H37Rv SSLSG-KAGAGGAGGSAGLFYGSGGAGGNGG--------------YSLNG
MMAR_0755|M.marinum_M GGGGG-GGGVGGAGGNAGVVYGDGGAGGAGGG--------GTVAAGAAGG
MUL_3062|M.ulcerans_Agy99 GTSTG-IGGAGGRGGNAGLLFSDAGVGGFGG----------------FGG
TH_3810|M.thermoresistible__bu VSREGIMPSSRAASARAGAACASSTSRSRRS----------------FCC
MAB_4284c|M.abscessus_ATCC_199 VGGSTAVGGGAHTGVGGGVNTGVGVGSHVGG---------------GISE
MAV_4827|M.avium_104 -GGHVPTPGAGGSGGSGGGHVPTPGTGGPGG----------------TGG
MLBr_01556|M.leprae_Br4923 VALRVIDRGVGGITETNVNLASASDAIIIGFN-------------VRAEG
.
Mflv_5091|M.gilvum_PYR-GCK TNGA-NGANGSQGAAGKAGATGTTGATG--------AAGEDGDAGSGGSG
Mvan_1264|M.vanbaalenii_PYR-1 TNGA-NGANGSQGAAGKAGATGTTGATG--------AAGDAGDPGSEAVD
MSMEG_0868|M.smegmatis_MC2_155 HGGAGNGGNGGKGADGWVQAYDPAGPVGSKIANSSAVAGNGGDGGVNGTG
Mb1789c|M.bovis_AF2122/97 TGG-------DGGTGGAGQITGLRSGFG----------GAGGAGG--ASD
Rv1759c|M.tuberculosis_H37Rv TGG-------DGGTGGAGQITGLRSGFG----------GAGGAGG--ASD
MMAR_0755|M.marinum_M SGGNAAMLFGNGGAGGTGAVGAAVGGNG----------GTGGDGGGLSGS
MUL_3062|M.ulcerans_Agy99 TGGNAG-WLGSGGSGGAGGGSNGDGGAG----------GTGGSGGQIVGD
TH_3810|M.thermoresistible__bu SRA-----------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 SLGGSGSVGGSTAVGGGAHTSAINDALG----------GSGSVGGSTAVG
MAV_4827|M.avium_104 SGGGHVPTPGAGTPGGSGGGHLPFPGAG---------STPGGSGGGHLPT
MLBr_01556|M.leprae_Br4923 KATELASREGVEIRYYLVIYQAIDDIEKALRGMLKPIYEENQLGRAEIRA
Mflv_5091|M.gilvum_PYR-GCK -INGGAGGAGG-----------AGGEGGEGG-------DGGKGGAGAE--
Mvan_1264|M.vanbaalenii_PYR-1 -INGGAGGAGG-----------AGGEGGEGG-------AGGAGGDGSE--
MSMEG_0868|M.smegmatis_MC2_155 GASGGDGGNGGNTSVWKSGGQTADGEHNTGG-------NGGNGGDGSEPG
Mb1789c|M.bovis_AF2122/97 TGAGGNGGAGG-----------KAGLYGNGG-------DGGAGGDG----
Rv1759c|M.tuberculosis_H37Rv TGAGGNGGAGG-----------KAGLYGNGG-------DGGAGGDG----
MMAR_0755|M.marinum_M GGAGGNGAGGG-----------TGGTGGDGGRARGLLGDGGTGGDGGFGG
MUL_3062|M.ulcerans_Agy99 GGAGGAGGQGD-----------LLAAGGSGG-------DGGQGGDA-VLI
TH_3810|M.thermoresistible__bu --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 GGAHTSAINES----------------------------MNSSINASHSS
MAV_4827|M.avium_104 PGAGTPGGGLG----------------------------GFGGGHAPAPG
MLBr_01556|M.leprae_Br4923 LFRSSKVGIIAG--------------------------CIISSGVVRRNA
Mflv_5091|M.gilvum_PYR-GCK ------GGAGGGGGAGGSGAGGAG----------GAGGSGG---------
Mvan_1264|M.vanbaalenii_PYR-1 ------GGAGGSGGAGGSGTGGAG----------GAGGSGG---------
MSMEG_0868|M.smegmatis_MC2_155 PGGNGAGGAGGNGGTGGTTAGGSGNG--------GNGGNGG---------
Mb1789c|M.bovis_AF2122/97 -ATSGKGGAGGNAVVIGNGGNG------------GNAGKAG---------
Rv1759c|M.tuberculosis_H37Rv -ATSGKGGAGGNAVVIGNGGNG------------GNAGKAG---------
MMAR_0755|M.marinum_M -ITSGDGGNGGTGALIGDGGNGGAGGIGLGAAPGGDGGKGGDAQLVGTGG
MUL_3062|M.ulcerans_Agy99 -GTGGNGGNGASGVLAGIGGDGGSRG-----LLLGEDGVNG---------
TH_3810|M.thermoresistible__bu --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 SMNESFGSSMGSHGAAGTGFEAQG-------------HAQG---------
MAV_4827|M.avium_104 ---GGLGGGGGHAPAPGGGLGGFG------------GGHSG---------
MLBr_01556|M.leprae_Br4923 KVRLLRDNIVVTDNLTVTSLRREKDDVTEVREGFECGMTLG---------
Mflv_5091|M.gilvum_PYR-GCK ------------SGGSGGSGGSGGAAGDSDD---
Mvan_1264|M.vanbaalenii_PYR-1 ------------SGGSGGAGGSGGAAGDSD----
MSMEG_0868|M.smegmatis_MC2_155 ------------NGGADGTPGTAGTTGANNP---
Mb1789c|M.bovis_AF2122/97 -----------GTAGAGGAGGLVLGRDGQHGLT-
Rv1759c|M.tuberculosis_H37Rv -----------GTAGAGGAGGLVLGRDGQHGLT-
MMAR_0755|M.marinum_M NGGILGLGLPPGTAGTGGTGGTLIGENGHDGA--
MUL_3062|M.ulcerans_Agy99 ------------EAAPPMTHIVLLGGDFPAAAS-
TH_3810|M.thermoresistible__bu ----------------------------------
MAB_4284c|M.abscessus_ATCC_199 -------------HASETAHTTLPGAEHH-----
MAV_4827|M.avium_104 ----------------GGLGGLGGGHK-------
MLBr_01556|M.leprae_Br4923 -------------YSDIKEGDVIESYELVEKQRA