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MVSTHAVVAGETLSALALRFYGDAELYRLIAAASGIADPDVVNVGQRLIMPDFTRYTVVAGDTLSALAAR FYGDASLYPLIAAVNGIADPGVIDVGQVLVIFIGRSDGFGLRIVDRNENDPRLWYYRFQTSAIGWNPGVN VLLPDDYRTSGRTYPVLYLFHGGGTDQDFRTFDFLGIRDLTAGKPIIIVMPDGGHAGWYSNPVSSFVGPR NWETFHIAQLLPWIEANFRTYAEYDGRAVAGFSMGGFGALKYAAKYYGHFASASSHSGPASLRRDFGLVV HWANLSSAVLDLGGGTVYGAPLWDQARVSADNPVERIDSYRNKRIFLVAGTSPDPANWFDSVNETQVLAG QREFRERLSNAGIPHESHEVPGGHVFRPDMFRLDLDGIVARLRPASIGAAAERAD
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1319 | - | - | 100% (405) | hypothetical protein Mb1319 |
| M. bovis AF2122 / 97 | Mb3833c | fbpD | 1e-08 | 25.95% (262) | secreted MPT51/MPB51 antigen protein FBPD (MPT51/MPB51 |
| M. bovis AF2122 / 97 | Mb3834c | fbpA | 9e-08 | 30.47% (128) | secreted antigen 85-A FBPA (Mycolyl transferase 85A) |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. gilvum PYR-GCK | Mflv_4459 | - | 1e-09 | 32.81% (128) | putative esterase |
| M. tuberculosis H37Rv | Rv1288 | - | 0.0 | 98.75% (401) | hypothetical protein Rv1288 |
| M. leprae Br4923 | MLBr_02028 | fbpB | 5e-08 | 30.71% (127) | antigen 85A, mycolyltransferase |
| M. abscessus ATCC 19977 | MAB_4806c | - | 0.0 | 82.96% (399) | hypothetical protein MAB_4806c |
| M. marinum M | MMAR_3773 | - | 3e-09 | 58.70% (46) | hypothetical protein MMAR_3773 |
| M. avium 104 | MAV_0215 | - | 2e-07 | 25.63% (199) | antigen 85-C |
| M. smegmatis MC2 155 | MSMEG_3437 | - | 0.0 | 77.18% (447) | putative esterase family protein |
| M. thermoresistible (build 8) | TH_1961 | fbpA | 2e-09 | 28.02% (182) | SECRETED ANTIGEN 85-A FBPA (MYCOLYL TRANSFERASE 85A) |
| M. ulcerans Agy99 | MUL_3720 | - | 1e-09 | 45.07% (71) | hypothetical protein MUL_3720 |
| M. vanbaalenii PYR-1 | Mvan_1902 | - | 8e-10 | 32.81% (128) | putative esterase |
CLUSTAL 2.0.9 multiple sequence alignment
Mb1319|M.bovis_AF2122/97 MVSTHAVVAGETLSALALRFYGDAELYRLIAAAS----------------
Rv1288|M.tuberculosis_H37Rv MVSTHAVVAGETLSALALRFYGDAELYRLIAAASGIADPDVVNVGQRLIM
MAB_4806c|M.abscessus_ATCC_199 MVRTHTVVAGDTLWQLALRFYGDAELYRLIATASGISDPGAIGVGRRLVI
MSMEG_3437|M.smegmatis_MC2_155 MVRTHTVAAGETLSGLALRFYGEADLYPLIATASGIPDPGVIAVGQRLIF
MMAR_3773|M.marinum_M --------------------------------------------------
MUL_3720|M.ulcerans_Agy99 --------------------------------------------------
Mflv_4459|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_1902|M.vanbaalenii_PYR-1 --------------------------------------------------
MLBr_02028|M.leprae_Br4923 --------------------------------------------------
TH_1961|M.thermoresistible__bu --------------------------------------------------
MAV_0215|M.avium_104 --------------------------------------------------
Mb1319|M.bovis_AF2122/97 -----------------------------------GIADPDVVNVGQRLI
Rv1288|M.tuberculosis_H37Rv PDFTRYTVVAGDTLSALALRFYGDAELNWLIAAASGIADPDVVNVGQRLI
MAB_4806c|M.abscessus_ATCC_199 PDVTRYTVVAGDTLSALALRFYGDAELYRLIAAVNGISDPGAIGVGRRLV
MSMEG_3437|M.smegmatis_MC2_155 PDFVRHTVVPGETLSDVAARFYADAALAPLIAAASGIAPTTDAEAGQRLV
MMAR_3773|M.marinum_M ------------------------------------MPMSDTLTEGQQLV
MUL_3720|M.ulcerans_Agy99 --------------------------------------MSDTLTEGQQLV
Mflv_4459|M.gilvum_PYR-GCK -------------------------------------MRLLDRIRGPWAR
Mvan_1902|M.vanbaalenii_PYR-1 -------------------------------------MRLLDRIRGPWAR
MLBr_02028|M.leprae_Br4923 ------------------------------------MIDVSGKIR-AWGR
TH_1961|M.thermoresistible__bu -------------------------MNQVKMSGQEKAMNFSAKPRRNGSY
MAV_0215|M.avium_104 -------------------------------------MDMT-VVR---GV
Mb1319|M.bovis_AF2122/97 MPDFTRYTVVAGDTLSALAARFYGDASLYPLIAAVNGIADPGVIDVGQVL
Rv1288|M.tuberculosis_H37Rv MPDFTRYTVVAGDTLSALAARFYGDASLYPLIAAVNGIADPGVIDVGQVL
MAB_4806c|M.abscessus_ATCC_199 IPDVTRYTVVAGDTLSALALRFYGDAELYRLIAAVNGIADPTALDAGRVL
MSMEG_3437|M.smegmatis_MC2_155 IPDITRYPVVAGDTLSALATRFYGDSAFYPLIAAVNGIPNPNVIEVGRVL
MMAR_3773|M.marinum_M P----GESLVSKNGAYTLTLQDDGN-----LVLASRGTPLWATATNGQQV
MUL_3720|M.ulcerans_Agy99 P----GESLVSKNGAYTLTLQDDGN-----LVLASRGTPLWASATNGQQV
Mflv_4459|M.gilvum_PYR-GCK RLGIATLAALLLPGVVGLTGGSVTAGAFSRPGLPVEYLMVPSPSMGRDIK
Mvan_1902|M.vanbaalenii_PYR-1 RLGIAALAAVLLPGVVGLTGGSATAGAFSRPGLPVEYLMVPSPSMGRDIK
MLBr_02028|M.leprae_Br4923 WLLVG--AAATLPSLISLAGGAATASAFSRPGLPVEYLQVPSEAMGRSIK
TH_1961|M.thermoresistible__bu RHWFRR-LGAVIAALVLLPALTAVVGAMPRAQAAPETLMVPSPSMGRDIP
MAV_0215|M.avium_104 SALLRVFCIAVLAAGLGVALQPAAVTGAAR-AAGYESLMVPSAAMGRDIP
:. .
Mb1319|M.bovis_AF2122/97 VIFIGRSDGFGLRIVDRNENDPRLWYYRFQTSAIGWNPGVNVLLPDDYRT
Rv1288|M.tuberculosis_H37Rv VIFIGRSDGFGLRIVDRNENDPRLWYYRFQTSAIGWNPGVNVLLPDDYRT
MAB_4806c|M.abscessus_ATCC_199 LIFRGRSDGFGLTIVDRNEDDPRLWYYRFQTDAIGWNPGVNVLLPDDYRT
MSMEG_3437|M.smegmatis_MC2_155 LIFAGRSDGFGLRIVDRNESDPRLWYYRFQTAAVGWNPGINVLLPDDYRT
MMAR_3773|M.marinum_M VRAEVQRDGN---FVVYTADKP-----VWHTDTKGKKN-VRLVLQDD---
MUL_3720|M.ulcerans_Agy99 VRAEVQRDGN---FVVYTADKP-----VWHTDTKGKKN-VRLVLQDD---
Mflv_4459|M.gilvum_PYR-GCK VQFQSGGPNSPALYLLDG--------LRAQDDFNGWDINTQAFEWYL---
Mvan_1902|M.vanbaalenii_PYR-1 IQFQSGGPNSPALYLLDG--------LRAQDDFNGWDINTQAFEWYL---
MLBr_02028|M.leprae_Br4923 VQFQNGGNGSPAVYLLDG--------LRAQDDYNGWDINTSAFEWYY---
TH_1961|M.thermoresistible__bu VQFQGGGEK--AVYLLDG--------MRARDDRNGWDIETGAFSWFE---
MAV_0215|M.avium_104 VAFLAGGPH--AVYLLDA--------FNAAPDVSNWVTAGNAMNTLG---
: : . .
Mb1319|M.bovis_AF2122/97 SGRTYPVLYLFHGGGTDQDFRTFDFLGIRDLTAGKPIIIVMPDGGHAGWY
Rv1288|M.tuberculosis_H37Rv SGRTYPVLYLFHGGGTDQDFRTFDFLGIRDLTAGKPIIIVMPDGGHAGWY
MAB_4806c|M.abscessus_ATCC_199 SGRTYPVLYMLHGG--AADFRQFDFLGIRDLTAGRPIIVVMPDGGQAGWY
MSMEG_3437|M.smegmatis_MC2_155 SGKTYPVLYLLHGGG-DQDFRTFDFLGIRNWTAGKPIIVVMPDGGHAGWY
MMAR_3773|M.marinum_M ----------------------------------RNLVLYAADG------
MUL_3720|M.ulcerans_Agy99 ----------------------------------RNLVLYAADG------
Mflv_4459|M.gilvum_PYR-GCK ---------------------------------DSGISVVMPVGGQSSFY
Mvan_1902|M.vanbaalenii_PYR-1 ---------------------------------DSGISVIMPVGGQSSFY
MLBr_02028|M.leprae_Br4923 ---------------------------------QSGLSVVMPVGGQSSFY
TH_1961|M.thermoresistible__bu ---------------------------------GSGLSVVAPVGGMSSFY
MAV_0215|M.avium_104 ---------------------------------GKGISVVAPAGGAWSMY
: : . *
Mb1319|M.bovis_AF2122/97 SNPVSSFVGP-----RNWETFHIAQLLPWIEANFRTYAEYDGRAVAGFSM
Rv1288|M.tuberculosis_H37Rv SNPVSSFVGP-----RNWETFHIAQLLPWIEANFRTYAEYDGRAVAGFSM
MAB_4806c|M.abscessus_ATCC_199 CNPVGSFVGP-----RNWETFHMAQLIPWIEANFRTYAEYDGRAVSGFSM
MSMEG_3437|M.smegmatis_MC2_155 SNPVASFVGP-----RNWETFHIAQLLPWVEANFRTYAEYDGRAVAGFSM
MMAR_3773|M.marinum_M ---------------PAWSTHTETDAPPPPEP------------------
MUL_3720|M.ulcerans_Agy99 ---------------PAWSTHTETDAPPPPEP------------------
Mflv_4459|M.gilvum_PYR-GCK SNWYKPACGKNGCLTYNWETFLTQELPAWLQAN--RDVRPTNNAAVGLSM
Mvan_1902|M.vanbaalenii_PYR-1 SNWYKPACGKSGCLTYNWETFLTQELPGWLQAN--RDVKPTGSAAVGLSM
MLBr_02028|M.leprae_Br4923 SDWYSPACGKAGCTTYKWETFLTSELPKWLSAN--RSVKSTGSAVVGLSM
TH_1961|M.thermoresistible__bu TDWYGPAVGNGRTQTYKWETFLTSELPAWLAEN--RGVSPSGNAVVGVSM
MAV_0215|M.avium_104 TNWEQDGSKQ-------WDTFLSSELPDWLAAN--KGLAPGGHAAVGASQ
*.*. :
Mb1319|M.bovis_AF2122/97 GGFGALKYAAKYYGHFASASSHSGPASLRRDFGLVVHWANLSSAVLDLGG
Rv1288|M.tuberculosis_H37Rv GGFGALKYAAKYYGHFASASSHSGPASLRRDFGLVVHWANLSSAVLDLGG
MAB_4806c|M.abscessus_ATCC_199 GGFGALKYAAKYYGHFASVSSHSGPASLRRDGGLVVHWANLSSAAVELGG
MSMEG_3437|M.smegmatis_MC2_155 GGFGALKYAAKYYGHFASVSSHSGPASLRRDFGLVVHWANLTSAVLDLGG
MMAR_3773|M.marinum_M ----------------TAAAEATASDTAQR--------------------
MUL_3720|M.ulcerans_Agy99 ----------------TAAAEATASDTAQR--------------------
Mflv_4459|M.gilvum_PYR-GCK AGGSSLVLAAHHPGQFSYAGSMSGFLNPSEGWWPGLINISMGDAG-GYKA
Mvan_1902|M.vanbaalenii_PYR-1 AGGSSLVLAAHHPGQFVWAGSMSGFLNPSEGWWPGLINISMGDAG-GYKA
MLBr_02028|M.leprae_Br4923 AGSSALILAAYHPDQFIYAGSLSALMDSSQGIEPQLIGLAMGDAG-GYKA
TH_1961|M.thermoresistible__bu SGSSALILAAYHPGQFSYAGSLSGYLNLSEDYWPLLIAVAMADAG-GFNA
MAV_0215|M.avium_104 GGYGAMALAAFHPDRFGFAGSLSGFLYPSSTNYNGAILAGLQQYG-GVDG
... :.
Mb1319|M.bovis_AF2122/97 GTVYGAPLWDQARVSADNPVERIDSYRNKRIFLVAGTSPDPAN-------
Rv1288|M.tuberculosis_H37Rv GTVYGAPLWDQARVSADNPVERIDSYRNKRIFLVAGTSPDPAN-------
MAB_4806c|M.abscessus_ATCC_199 ATVYGVP-WDEARVSADNPVERIESYRNKRIFTVAGTSPDPVN-------
MSMEG_3437|M.smegmatis_MC2_155 GTVYGAPLWDQARVSADNPVERIESYRNKRVFLVAGTSPDPLN-------
MMAR_3773|M.marinum_M --VDTTPEPVAAAVAEPAPPEPAAEPAPRTYTVVSGDT------------
MUL_3720|M.ulcerans_Agy99 --VDTTPEAVAAAVAEPAPPEPAAEPAPRTYTVVSGDT------------
Mflv_4459|M.gilvum_PYR-GCK NDMWGPAETDPAWQYNDPMVQIPNLVANNSRIWVYCGNGTPNE----LGG
Mvan_1902|M.vanbaalenii_PYR-1 NDMWGPAETDPAWQYNDPMVQIPRLVANNSRIWVYCGNGQPNE----LGG
MLBr_02028|M.leprae_Br4923 ADMWGPPN-DPAWQRNDPILQAGKLVANNTHLWVYCGNGTPSE----LGG
TH_1961|M.thermoresistible__bu LDMWGPYG-GPAWQRNDPMLQVGRLVANGTRIWVYTGNGNPTELDAGLGD
MAV_0215|M.avium_104 NGMWGAPQ-LGRWKWHDPYVHASLLAQNNTRVWVWS----PTN----MGG
: . *
Mb1319|M.bovis_AF2122/97 --WFDSVNETQVLAGQREFRERLSNAGIPHESHEVPGGHVFRPDMFRLDL
Rv1288|M.tuberculosis_H37Rv --WFDSVNETQVLAGQREFRERLSNAGIPHESHEVPGGHVFRPDMFRLDL
MAB_4806c|M.abscessus_ATCC_199 --WFDTVQETQVLAGQREFRGRLSDAGIPHEFREEPGGHVFRPDMFVLDL
MSMEG_3437|M.smegmatis_MC2_155 --WFDSVNETQVLAGQREFRERLRAAGIPHEAHEVPGGHIFRPEMFIRDL
MMAR_3773|M.marinum_M ---LWAIAERFYGDGSK-YQVIAEASGVANPDLIHPGEVLTIP-------
MUL_3720|M.ulcerans_Agy99 ---LWAIAERFYGDGSK-YQVIAEASGVANPDLIHPGEVLTIP-------
Mflv_4459|M.gilvum_PYR-GCK GDLPATFLEGLTIRTNRTFQDNYLAAGGKNGVFNFPNNGTHNWAYWGREL
Mvan_1902|M.vanbaalenii_PYR-1 GDLPATFLEGLTIRTNRTFQDNYIAAGGTNGVFNFPNNGTHNWAYWGREL
MLBr_02028|M.leprae_Br4923 TNVPAEFLENFVHGSNLKFQDAYNGAGGHNAVFNLNADGTHSWEYWGAQL
TH_1961|M.thermoresistible__bu AQIPAQFLEGLTVRTSREFQRAYQRAGGTNAVFNFPASGTHSWGYWGGQL
MAV_0215|M.avium_104 DDAAMIGQAGAAMGSSREFYQQYRSNGGHNGHFDFPGGGDNGWGSWAGQL
. : * :
Mb1319|M.bovis_AF2122/97 DGIVARLRPASIGAAAERAD
Rv1288|M.tuberculosis_H37Rv DGIVARLRPASIGAAAERAD
MAB_4806c|M.abscessus_ATCC_199 DGIIARLRPASASVAV----
MSMEG_3437|M.smegmatis_MC2_155 DGIIARLRPAAAVEV-----
MMAR_3773|M.marinum_M --------------------
MUL_3720|M.ulcerans_Agy99 --------------------
Mflv_4459|M.gilvum_PYR-GCK QAMKPDLQAHLLG-------
Mvan_1902|M.vanbaalenii_PYR-1 QAMKPDLQAHLL--------
MLBr_02028|M.leprae_Br4923 NAMKPDLQNTLMAVPRSG--
TH_1961|M.thermoresistible__bu QAMIPDIQRTLGAAPAE---
MAV_0215|M.avium_104 GAMSGDIVGAIR--------