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MIDVSGKIRAWGRWLLVGAAATLPSLISLAGGAATASAFSRPGLPVEYLQVPSEAMGRSIKVQFQNGGNG SPAVYLLDGLRAQDDYNGWDINTSAFEWYYQSGLSVVMPVGGQSSFYSDWYSPACGKAGCTTYKWETFLT SELPKWLSANRSVKSTGSAVVGLSMAGSSALILAAYHPDQFIYAGSLSALMDSSQGIEPQLIGLAMGDAG GYKAADMWGPPNDPAWQRNDPILQAGKLVANNTHLWVYCGNGTPSELGGTNVPAEFLENFVHGSNLKFQD AYNGAGGHNAVFNLNADGTHSWEYWGAQLNAMKPDLQNTLMAVPRSG
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. leprae Br4923 | MLBr_02028 | fbpB | - | 100% (327) | antigen 85A, mycolyltransferase |
| M. leprae Br4923 | MLBr_00097 | fbpA | e-138 | 71.65% (321) | antigen 85A, mycolytransferase |
| M. leprae Br4923 | MLBr_02655 | fbpC2 | e-115 | 63.07% (306) | secreted antigen 85A, mycolyltransferase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1918c | fbpB | 1e-162 | 83.02% (324) | secreted antigen 85-B fbpB (85B) (antigen 85 complex B) |
| M. gilvum PYR-GCK | Mflv_4459 | - | 1e-124 | 66.24% (314) | putative esterase |
| M. tuberculosis H37Rv | Rv1886c | fbpB | 1e-162 | 83.02% (324) | secreted antigen 85-B fbpB (85B) (antigen 85 complex B) |
| M. abscessus ATCC 19977 | MAB_0176 | - | 1e-103 | 59.80% (306) | antigen 85-A precursor |
| M. marinum M | MMAR_2777 | fbpB | 1e-161 | 82.10% (324) | secreted antigen 85-B FbpB |
| M. avium 104 | MAV_2816 | - | 1e-161 | 81.76% (329) | antigen 85-B |
| M. smegmatis MC2 155 | MSMEG_2078 | - | 1e-127 | 67.71% (319) | antigen 85-C |
| M. thermoresistible (build 8) | TH_2078 | fbpA | 1e-119 | 64.20% (324) | SECRETED ANTIGEN 85-A FBPA (MYCOLYL TRANSFERASE 85A) |
| M. ulcerans Agy99 | MUL_2970 | fbpB | 1e-159 | 80.86% (324) | secreted antigen 85-B FbpB |
| M. vanbaalenii PYR-1 | Mvan_1902 | - | 1e-126 | 66.24% (314) | putative esterase |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_4459|M.gilvum_PYR-GCK ---MRLLD-RIRGPWARRLGIATLAALLLPGVVGLTGG---SVTAGAFSR
Mvan_1902|M.vanbaalenii_PYR-1 ---MRLLD-RIRGPWARRLGIAALAAVLLPGVVGLTGG---SATAGAFSR
MSMEG_2078|M.smegmatis_MC2_155 ---MTFID-KIRGHWARRMTVAAVAALLLPGLVGVVGG---SATAGAFSR
Mb1918c|M.bovis_AF2122/97 ---MTDVS-RKIRAWGRRLMIGTAAAVVLPGLVGLAGG---AATAGAFSR
Rv1886c|M.tuberculosis_H37Rv ---MTDVS-RKIRAWGRRLMIGTAAAVVLPGLVGLAGG---AATAGAFSR
MMAR_2777|M.marinum_M ---MTDVS-GKIRTWGRRLLIGAAAAITLPGLVGLAGG---APAAKAFSR
MUL_2970|M.ulcerans_Agy99 ---MTDVS-GKIRTWGRRLLIGAAAAITLPGLVGVAGG---APAAKAFSR
MAV_2816|M.avium_104 ---MTDLS-EKVRAWGRRLLVGAAAAVTLPGLIGLAGG---AATANAFSR
MLBr_02028|M.leprae_Br4923 ---MIDVS-GKIRAWGRWLLVGAAA--TLPSLISLAGG---AATASAFSR
TH_2078|M.thermoresistible__bu MKLVAKLR-GAARALPRRLTVAALAAALLPGLVGAFGG---SATAGAFSR
MAB_0176|M.abscessus_ATCC_1997 MKLFSKMRGALARQSARRIAVAATAVAVLPGVAGIVGGTALTPVAGAFSR
. : * : :.: * **.: . ** : .* ****
Mflv_4459|M.gilvum_PYR-GCK PGLPVEYLMVPSPSMGRDIKVQFQSGGPNSPALYLLDGLRAQDDFNGWDI
Mvan_1902|M.vanbaalenii_PYR-1 PGLPVEYLMVPSPSMGRDIKIQFQSGGPNSPALYLLDGLRAQDDFNGWDI
MSMEG_2078|M.smegmatis_MC2_155 PGLPVEYLMVPSPSMGRDIKVQFQSGGPGSHAVYLLDGLRAQDDFNGWDI
Mb1918c|M.bovis_AF2122/97 PGLPVEYLQVPSPSMGRDIKVQFQSGGNNSPAVYLLDGLRAQDDYNGWDI
Rv1886c|M.tuberculosis_H37Rv PGLPVEYLQVPSPSMGRDIKVQFQSGGNNSPAVYLLDGLRAQDDYNGWDI
MMAR_2777|M.marinum_M PGLPVEYLQVPSAAMGRSIKVQFQSGGDNSPAVYLLDGLRAQDDYNGWDI
MUL_2970|M.ulcerans_Agy99 PGLPVEYLQVPSAAMGRSIKVQFQSGGDNSPAVYLLDGLRAQDDYNGWDI
MAV_2816|M.avium_104 PGLPVEYLQVPSAGMGRDIKVQFQSGGNGSPAVYLLDGLRAQDDYNGWDI
MLBr_02028|M.leprae_Br4923 PGLPVEYLQVPSEAMGRSIKVQFQNGGNGSPAVYLLDGLRAQDDYNGWDI
TH_2078|M.thermoresistible__bu PGLPVEYLMVPSAAMGRDIKVQFQSGGEGSPGVYLLDGLRARDDFNGWDI
MAB_0176|M.abscessus_ATCC_1997 PGLPVEYLQVPSASMGREIKVQFQPGG--AKAVYLLDGLRARDDFSGWDI
******** *** .***.**:*** ** : .:********:**:.****
Mflv_4459|M.gilvum_PYR-GCK NTQAFEWYLDSGISVVMPVGGQSSFYSNWYKPACGKNGCLTYNWETFLTQ
Mvan_1902|M.vanbaalenii_PYR-1 NTQAFEWYLDSGISVIMPVGGQSSFYSNWYKPACGKSGCLTYNWETFLTQ
MSMEG_2078|M.smegmatis_MC2_155 NTNAFEMFLDSGLSVVMPVGGQSSFYSDWYQPACGNNGCVTYKWETFLTS
Mb1918c|M.bovis_AF2122/97 NTPAFEWYYQSGLSIVMPVGGQSSFYSDWYSPACGKAGCQTYKWETFLTS
Rv1886c|M.tuberculosis_H37Rv NTPAFEWYYQSGLSIVMPVGGQSSFYSDWYSPACGKAGCQTYKWETFLTS
MMAR_2777|M.marinum_M NTPAFEWYYQSGLSVIMPVGGQSSFYANWYQPACGKAGCSTYKWETFLTS
MUL_2970|M.ulcerans_Agy99 NTPAFEWYYQSGLSVIMPVGGQSSFYANWYQPACGKSGCSTYKWETFLTS
MAV_2816|M.avium_104 NTPAFEWYYQSGLSVIMPVGGQSSFYADWYQPACGKAGCSTYKWETFLTS
MLBr_02028|M.leprae_Br4923 NTSAFEWYYQSGLSVVMPVGGQSSFYSDWYSPACGKAGCTTYKWETFLTS
TH_2078|M.thermoresistible__bu ETAAFEWYYESGLSVIMPVGGQSSFYSDWYSPACGNNGCQTYKWETFLTQ
MAB_0176|M.abscessus_ATCC_1997 ETTAFEDYYQSGISMVMPVGGQSSFYTDWYNPAKGKDGVWTYKWETFTTQ
:* *** : :**:*::**********::**.** *: * **:**** *.
Mflv_4459|M.gilvum_PYR-GCK ELPAWLQANRDVRPTNNAAVGLSMAGGSSLVLAAHHPGQFSYAGSMSGFL
Mvan_1902|M.vanbaalenii_PYR-1 ELPGWLQANRDVKPTGSAAVGLSMAGGSSLVLAAHHPGQFVWAGSMSGFL
MSMEG_2078|M.smegmatis_MC2_155 ELPEWLAANRDVAATGNAAIGLSMAGSAALILAAYHPDRFIYAGSMSGFL
Mb1918c|M.bovis_AF2122/97 ELPQWLSANRAVKPTGSAAIGLSMAGSSAMILAAYHPQQFIYAGSLSALL
Rv1886c|M.tuberculosis_H37Rv ELPQWLSANRAVKPTGSAAIGLSMAGSSAMILAAYHPQQFIYAGSLSALL
MMAR_2777|M.marinum_M ELPEWLSANRSVKPTGSAAVGISMSGSSAMILAVYHPQQFVYAGSLSALL
MUL_2970|M.ulcerans_Agy99 ELPEWLSANRSVKPTGSAAIGISMSGSSAMILAVYHPQQFVYAGSLSALL
MAV_2816|M.avium_104 ELPSYLASNKGVKRTGSAAVGISMSGSSAMILAVNHPDQFIYAGSLSALL
MLBr_02028|M.leprae_Br4923 ELPKWLSANRSVKSTGSAVVGLSMAGSSALILAAYHPDQFIYAGSLSALM
TH_2078|M.thermoresistible__bu ELPAYLASNYGVDRNRNAAVGLSMAGSAALVLAIYYPQQFQYAASLSGFL
MAB_0176|M.abscessus_ATCC_1997 ELPAYLAANKGISQTGNAVVGLSMGASAALTLSIYHPQLFVYAGALSGFL
*** :* :* : . .*.:*:**...::: *: :* * :*.::*.::
Mflv_4459|M.gilvum_PYR-GCK NPSEGWWPGLINISMGDAGGYKANDMWGPAET-DPAWQYNDPMVQIPNLV
Mvan_1902|M.vanbaalenii_PYR-1 NPSEGWWPGLINISMGDAGGYKANDMWGPAET-DPAWQYNDPMVQIPRLV
MSMEG_2078|M.smegmatis_MC2_155 NPSEGWWPFLINISMGDAGGYKANDMWGPTEDPNSAWKRNDPMVQIPRLV
Mb1918c|M.bovis_AF2122/97 DPSQGMGPSLIGLAMGDAGGYKAADMWGPSSD--PAWERNDPTQQIPKLV
Rv1886c|M.tuberculosis_H37Rv DPSQGMGPSLIGLAMGDAGGYKAADMWGPSSD--PAWERNDPTQQIPKLV
MMAR_2777|M.marinum_M DPSQGMGPSLIGLAMGDAGGYKAGDMWGPSSD--PAWQRNDPTIQIPALV
MUL_2970|M.ulcerans_Agy99 DPSQGMGPFLIGLAMGDAGGYKAGDMWGPSSD--PAWQRNDPTIQIPALV
MAV_2816|M.avium_104 DPSQGMGPSLIGLAMGDAGGYKADAMWGPSSD--PAWQRNDPSLHIPELV
MLBr_02028|M.leprae_Br4923 DSSQGIEPQLIGLAMGDAGGYKAADMWGPPND--PAWQRNDPILQAGKLV
TH_2078|M.thermoresistible__bu NLSEGWWPMLVGLAMGDAGGYDPNDMWGRTEDPNSAWKRNDPMVNIDKLV
MAB_0176|M.abscessus_ATCC_1997 NPSD--MKFQIGLAMGDAGGFSASDMWGPDSD--PAWQRNDPFLNIQKII
: *: :.::******:.. *** . .**: *** : ::
Mflv_4459|M.gilvum_PYR-GCK ANNSRIWVYCGNGTPNELG-----GGDLPATFLEGLTIRTNRTFQDNYLA
Mvan_1902|M.vanbaalenii_PYR-1 ANNSRIWVYCGNGQPNELG-----GGDLPATFLEGLTIRTNRTFQDNYIA
MSMEG_2078|M.smegmatis_MC2_155 ANNTRIWVYCGNGQPNELG-----GGDLPATFLEGLTIRTNETFRDNYIA
Mb1918c|M.bovis_AF2122/97 ANNTRLWVYCGNGTPNELG-----GANIPAEFLENFVRSSNLKFQDAYNA
Rv1886c|M.tuberculosis_H37Rv ANNTRLWVYCGNGTPNELG-----GANIPAEFLENFVRSSNLKFQDAYNA
MMAR_2777|M.marinum_M SNNTRLWVYCGNGTPSELG-----GANLPAEFLENFVRSSNLKFQDAYNA
MUL_2970|M.ulcerans_Agy99 SNNTRLWVYCGNGTPSELG-----GASLPAEFLENFVRSSNLKFQDAYNA
MAV_2816|M.avium_104 GHNTRLWVYCGNGTPSELG-----GANMPAEFLENFVRSSNLKFQDAYNG
MLBr_02028|M.leprae_Br4923 ANNTHLWVYCGNGTPSELG-----GTNVPAEFLENFVHGSNLKFQDAYNG
TH_2078|M.thermoresistible__bu ANNTRIWVFCGDGTPADIGAGVPEGDNFNAKFLESFTLRTNKTFQQEYIA
MAB_0176|M.abscessus_ATCC_1997 DNGTRLWIYCGTGDSTDLDATRNGFENFTGGFLEGMAIGSNKKFVEAYTA
:.:::*::** * . ::. .. . ***.:. :* .* : * .
Mflv_4459|M.gilvum_PYR-GCK AGGKNGVFNFPNNGTHNWAYWGRELQAMKPDLQAHLLG------
Mvan_1902|M.vanbaalenii_PYR-1 AGGTNGVFNFPNNGTHNWAYWGRELQAMKPDLQAHLL-------
MSMEG_2078|M.smegmatis_MC2_155 AGGNNGVFNFPNNGTHNWAYWGRELQAMVPDLQRVLG-------
Mb1918c|M.bovis_AF2122/97 AGGHNAVFNFPPNGTHSWEYWGAQLNAMKGDLQSSLGAG-----
Rv1886c|M.tuberculosis_H37Rv AGGHNAVFNFPPNGTHSWEYWGAQLNAMKGDLQSSLGAG-----
MMAR_2777|M.marinum_M AGGHNAVFNFNDNGTHSWEYWGAQLNAMKGDLQASLGAA-----
MUL_2970|M.ulcerans_Agy99 AGGHNAVFNFNDNGTHSWEYWGAQLNAMKGDLQTSLGAA-----
MAV_2816|M.avium_104 AGGHNAVFNFNANGTHSWEYWGAQLNAMKPDLQGTLGASPGGGG
MLBr_02028|M.leprae_Br4923 AGGHNAVFNLNADGTHSWEYWGAQLNAMKPDLQNTLMAVPRSG-
TH_2078|M.thermoresistible__bu AGGKNGVFNFPDAGTHSWGYWGQQLQQMKPDIQRVLGVSAA---
MAB_0176|M.abscessus_ATCC_1997 AGGKNAHIEFPPGGIHNWTYWGQQLRAMKPDMVAYLQSH-----
*** *. ::: * *.* *** :*. * *: *