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MDGTTGVWILGGYQSDFARNLTKENRDFADLTAEVVPGTLAAAQIEAADIGVVHVANAFGEMFAGQGHLG AMPATVSDGLWDTPASRHEAACASGSVATLAAIADLRSGFYNSALVVGLELEKTVPGDTAAQYLGAAGWT GHEGAEARYLWPSVFTQVADEYDRRYGLDDTHLHSIAQLNYANARRNPNAQTRGWTIPDPITDDDATNPI TEGRLRRLDCSQMTDGGAGLVLVNDAYLRDHPGARPIGRIDGWGHCTVGLGLQQKLDRPAQGESGQYVLP HVRKAALDALRRAHVSLDDLNGYEVHDCFTPSEYLAIDHIGLTGPGESWKAIENGEIEIGGRLPINPSGG LIGGGHPVGASGVRMLLDAAKQVSGAAGDYQVENATKFGTLNFGGSTATTVSFVVSTTKDA
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. marinum M | MMAR_4613 | - | - | 100% (411) | lipid carrier protein or keto acyl-CoA thiolase |
| M. marinum M | MMAR_1918 | ltp1 | 6e-33 | 27.14% (409) | lipid-transfer protein Ltp1 |
| M. marinum M | MMAR_0142 | ltp1_1 | 1e-28 | 28.64% (405) | lipid-transfer protein Ltp1_1 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0938c | - | 0.0 | 87.47% (407) | acetyl-CoA acetyltransferase |
| M. gilvum PYR-GCK | Mflv_1808 | - | 1e-180 | 75.12% (402) | acetyl-CoA acetyltransferase |
| M. tuberculosis H37Rv | Rv0914c | - | 0.0 | 87.47% (407) | acetyl-CoA acetyltransferase |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_2951c | - | 7e-33 | 28.91% (384) | lipid-transfer protein |
| M. avium 104 | MAV_5079 | - | 5e-37 | 31.87% (364) | acetyl-CoA acetyltransferase |
| M. smegmatis MC2 155 | MSMEG_5608 | - | 0.0 | 77.48% (404) | acetyl-CoA acetyltransferase |
| M. thermoresistible (build 8) | TH_3699 | - | 1e-38 | 32.17% (401) | PUTATIVE thiolase |
| M. ulcerans Agy99 | MUL_2143 | ltp1 | 2e-33 | 27.38% (409) | lipid-transfer protein |
| M. vanbaalenii PYR-1 | Mvan_4939 | - | 0.0 | 75.56% (405) | acetyl-CoA acetyltransferase |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_1808|M.gilvum_PYR-GCK --MRSADDVWILGGYQSDFACNYHRD-----GRGFSELTAEVVESTLRDA
Mvan_4939|M.vanbaalenii_PYR-1 ---MSSTGVWILGGYQSDFARNYDRE-----GLDFAGLTAEVVEATLEAS
Mb0938c|M.bovis_AF2122/97 --MD--DGVWILGGYQSDFARNLSKE-----NRDFADLTREVVDGTLTAA
Rv0914c|M.tuberculosis_H37Rv --MD--DGVWILGGYQSDFARNLSKE-----NRDFADLTREVVDGTLTAA
MMAR_4613|M.marinum_M --MDGTTGVWILGGYQSDFARNLTKE-----NRDFADLTAEVVPGTLAAA
MSMEG_5608|M.smegmatis_MC2_155 --MEN---VWVLGGYQSDFARNLTRE-----NLDFADLTREVVENTLAHA
MAV_5079|M.avium_104 ----------MPSNGIAGKVAVVAMG-----CSHFGERWDASTEDLILEA
TH_3699|M.thermoresistible__bu ----------MASNGIAGKVAVVGMG-----CTRFGERWDASADDLILEA
MAB_2951c|M.abscessus_ATCC_199 MAN----RVYVVGVGMTKFEKPGRRLNDDGSAWDYPDMARESGTKALADA
MUL_2143|M.ulcerans_Agy99 MPNNGSNRVFVIGVGMTKFEKPGRRE-----GWDYPDMARESGTNALNDA
: . : : : :
Mflv_1808|M.gilvum_PYR-GCK CVDARDIG---VVHVANAFGELFAHQGHLGAMPATVVDGLWDTPATRHEA
Mvan_4939|M.vanbaalenii_PYR-1 GVDAADIG---VVHVANAFGGLFARQGHLGAMPATVNDGLWGTPAVRHEA
Mb0938c|M.bovis_AF2122/97 KVDAADLAAAGVVHVANAFGEMFARQGHLGAMPATVCDDLWDTPATRHEA
Rv0914c|M.tuberculosis_H37Rv KVDAADLAAAGVVHVANAFGEMFARQGHLGAMPATVCDDLWDTPATRHEA
MMAR_4613|M.marinum_M QIEAADIG---VVHVANAFGEMFAGQGHLGAMPATVSDGLWDTPASRHEA
MSMEG_5608|M.smegmatis_MC2_155 KIDASDIG---VVHVANAFGELFARQGHLGAMPATVHEGLWDTPSSRHEA
MAV_5079|M.avium_104 YQECLDSVPNLGADDVDAFWLGTLSSG-LGGLTLSRAIGNDDKPVTRVEN
TH_3699|M.thermoresistible__bu YAEALDSAG-ISRDDIDAYWLGTLSSG-LGGLTLSRAIGSDDKPVTRVEN
MAB_2951c|M.abscessus_ATCC_199 GIG---------YDLVEQAYVGYVYGESTSGQRAVYELGMSGIPVVNVNN
MUL_2143|M.ulcerans_Agy99 GIE---------YREVEHAYVGYVYGESTSGQRAVYELGMTGIPVVNVNN
: .. . . * . :
Mflv_1808|M.gilvum_PYR-GCK ACASGSVAALAAIADLRSGAYRTALVVGVELEKTVPG-----DTATSILG
Mvan_4939|M.vanbaalenii_PYR-1 ACASGSVAALAAIADLRSGAYTSALVVGVELEKTVPG-----DEATSILG
Mb0938c|M.bovis_AF2122/97 ACASGSVATLAAMADLRSGAYRVALVVGLELEKTVPG-----DTAAEHLS
Rv0914c|M.tuberculosis_H37Rv ACASGSVATLAAMADLRSGAYRVALVVGLELEKTVPG-----DTAAEHLS
MMAR_4613|M.marinum_M ACASGSVATLAAIADLRSGFYNSALVVGLELEKTVPG-----DTAAQYLG
MSMEG_5608|M.smegmatis_MC2_155 ACASGSVAALAAIADLRSGAYDTALVVGVELEKTVPG-----DDAAANLG
MAV_5079|M.avium_104 FCATGSEAFRNACYAVAAGAYDVAMALGVEKLKDS--------GYSGLLR
TH_3699|M.thermoresistible__bu FCATGSEAFRNACYAVASGAYDIAMAVGVEKLKDS--------GYSGLLR
MAB_2951c|M.abscessus_ATCC_199 NCSTGSTALYLAAQSIRGGLADCALALGFEKMNPGSLGAMYDDRAQPMEK
MUL_2143|M.ulcerans_Agy99 NCSTGSTALFLAAQAIRGGLADCTVALGFEKMKPGSLSSSYDDRTQPMDK
*::** * * : .* ::.:*.* :
Mflv_1808|M.gilvum_PYR-GCK AAAWTGHEGRDAKFMWPHMFNAVADEYDRRYGLDESHLRAIADLNFTNAR
Mvan_4939|M.vanbaalenii_PYR-1 SAAWTGHEGQQAKYMWPYMFETVAAEYDRRYGLDESHLHAIASLNFANAK
Mb0938c|M.bovis_AF2122/97 AAAWTGHEGAEARYLWPSMFAQVADEYDRRYGLDDTHLRAIAQLNFANAR
Rv0914c|M.tuberculosis_H37Rv AAAWTGHEGAEARYLWPSMFAQVADEYDRRYGLDDTHLRAIAQLNFANAR
MMAR_4613|M.marinum_M AAGWTGHEGAEARYLWPSVFTQVADEYDRRYGLDDTHLHSIAQLNYANAR
MSMEG_5608|M.smegmatis_MC2_155 TAAWTGHEGADATYMWPWMFSKVADEYDRRYCLDPAHLRVIAAVNFANAR
MAV_5079|M.avium_104 QDPPGDGTAPELSMTAPAAFSMLDPAYCARHGVHPDEMRAAMTHVAWKNH
TH_3699|M.thermoresistible__bu QDPPGDGTAPEISMTAPAAFSMLDPAYCARYGVHPDEMRAAMTHVAWKNH
MAB_2951c|M.abscessus_ATCC_199 HILALAEISEVLFPPASWMFGAAGREHMQQYGSTAEHFAKIGHKNHKHSV
MUL_2143|M.ulcerans_Agy99 HVKALAQIAEFAFPVAPWMFGAAGREHMQQYGSTAEHFAKIGFKNHKHSV
. . * : :: .: :
Mflv_1808|M.gilvum_PYR-GCK ANPLAQTRDWSVPSPPTADDTSNPVVDGRLRRLDCSQLTDGGAGLVLVSD
Mvan_4939|M.vanbaalenii_PYR-1 TNPRAQTRTWAVPERVSADDTQNPVIEGRLRRLDCSQLTDGGAGVVLVSD
Mb0938c|M.bovis_AF2122/97 RNPNAQTRGWTIPDPITDDDATNPLTEGRLRRFDCSQMTDGGAGLVLVSD
Rv0914c|M.tuberculosis_H37Rv RNPNAQTRGWTIPDPITDDDATNPLTEGRLRRFDCSQMTDGGAGLVLVSD
MMAR_4613|M.marinum_M RNPNAQTRGWTIPDPITDDDATNPITEGRLRRLDCSQMTDGGAGLVLVND
MSMEG_5608|M.smegmatis_MC2_155 RNPNAQTRTWNVPDPLTDDDATNPVVEGRIRRFDCSQMTDGGAGVVLVTD
MAV_5079|M.avium_104 DNGTRNPKAQFRSPVSRDTIDNAPKVAGRLGVFDCSGISDGAACALIVPA
TH_3699|M.thermoresistible__bu DNGSRNPKAQFRSGVSKETIDKAVKVAGRLGVFDCSGVSDGAACAVIVPA
MAB_2951c|M.abscessus_ATCC_199 NNPYAQFQDEYT----LDDILNSRMIYDPLTKLQCSPTSDGSGAAILASE
MUL_2143|M.ulcerans_Agy99 NNPFAQFQEAYT----LDDILASRMIYEPLTKLRCSPTSDGSGAAILASE
* : : : : ** :**.. ::.
Mflv_1808|M.gilvum_PYR-GCK AWLRDNPAARPLGRIDGWGHRTVGLGLRQKLDH---SAGNPYVFPHVRSA
Mvan_4939|M.vanbaalenii_PYR-1 DWLRDHPTARPLGRIDGWGHRTVGLGLQQKLDH---SAGDPYVFPHVRAA
Mb0938c|M.bovis_AF2122/97 AYLRDHRDARPIGRIDGWGHRTVGLGLRQKLDRVAQGDSAPYLLPHVRAT
Rv0914c|M.tuberculosis_H37Rv AYLRDHRDARPIGRIDGWGHRTVGLGLRQKLDRVAQGDSAPYLLPHVRAT
MMAR_4613|M.marinum_M AYLRDHPGARPIGRIDGWGHCTVGLGLQQKLDRPAQGESGQYVLPHVRKA
MSMEG_5608|M.smegmatis_MC2_155 RWLRAHPGVTPQARIAGWGHRTVGLGLQQKIDR---ADADPYLLPHVRGA
MAV_5079|M.avium_104 ERAREYTDTPMYVEALSLIAGSARASMDPGYDFT--------TFPEVVKS
TH_3699|M.thermoresistible__bu DRAHEYTDTPMYVRALSLVSGSARGAVDAGYDYT--------TFPEVVRS
MAB_2951c|M.abscessus_ATCC_199 AFVDRHGLASQAVEIVGQAMTTDFQNSFDGTCKA------IIGYHMNVSA
MUL_2143|M.ulcerans_Agy99 SFVDSHGLAGRAVEIVGQAMTTDFASTFDGSAKN------LIGYDMNVQA
. . . : :
Mflv_1808|M.gilvum_PYR-GCK VQDAFGRARVT--LDEVDGFEVHDCFTPSEYLAIDHIGLTEPGQSWKAIE
Mvan_4939|M.vanbaalenii_PYR-1 VLDAFGRAEVT--LDDVDGFEVHDCFTPSEYLAIDHIGLTAPGESWKAIE
Mb0938c|M.bovis_AF2122/97 VLDALRRARVT--LDDLDGIEVHDCFTPSEYLAIDHIGLTGPGESWKAIE
Rv0914c|M.tuberculosis_H37Rv VLDALRRARVT--LDDLDGIEVHDCFTPSEYLAIDHIGLTGPGESWKAIE
MMAR_4613|M.marinum_M ALDALRRAHVS--LDDLNGYEVHDCFTPSEYLAIDHIGLTGPGESWKAIE
MSMEG_5608|M.smegmatis_MC2_155 VQDAFGRAQVT--LDDIDGFEVHDCFTPSEYLAIDHIGLTGPGESWKAIE
MAV_5079|M.avium_104 AKDAYTQAGIEHPARELSLAEVHDCFTPTEIVLMEDLGFSVAGNAWKDVL
TH_3699|M.thermoresistible__bu ARDAYAQAGIDDPATQLSFAEVHDCFTPTEIVLMEDLGFTEPGRAYKDVL
MAB_2951c|M.abscessus_ATCC_199 ARQVYDQSGLG--AEDFQVIELHDCFSANEFLLYEALGLCGEGEAGKLID
MUL_2143|M.ulcerans_Agy99 ARRVYQQSGLG--PEDFQVIELHDCFSANELLLYEALGLCGQGEAPKLID
. . :: : :.. *:****:..* : : :*: *.: * :
Mflv_1808|M.gilvum_PYR-GCK HGEIAIGGRLPVNPSGGLIGGGHPVGASGVRMLLDAARQVSDTAGDYQVE
Mvan_4939|M.vanbaalenii_PYR-1 HGEIALGGTLPINPSGGLIGGGHPVGASGVRMLLDAARQVSDTAGDYQVD
Mb0938c|M.bovis_AF2122/97 NGEIEIGGRLPINPSGGLIGGGHPVGASGVRMLLDAAKQVSGIAGDYQVE
Rv0914c|M.tuberculosis_H37Rv NGEIEIGGRLPINPSGGLIGGGHPVGASGVRMLLDAAKQVSGIAGDYQVE
MMAR_4613|M.marinum_M NGEIEIGGRLPINPSGGLIGGGHPVGASGVRMLLDAAKQVSGAAGDYQVE
MSMEG_5608|M.smegmatis_MC2_155 NGEIEISGRLPINPSGGLIGGGHPVGASGVRMLLDATKQVSASAGEYQVE
MAV_5079|M.avium_104 SGEFDADGRLPVNPDGGLKSFGHPVGASGLRMLYEAWLQFGGRAGARQLS
TH_3699|M.thermoresistible__bu SGEFDADGRLPVNIDGGLKSFGHPVGASGLRMLYEAWLQFRGAAGERQLA
MAB_2951c|M.abscessus_ATCC_199 NGDTTYGGRWVVNPSGGLISKGHPLGATGLAQCAELTWQLRGAADKRQVD
MUL_2143|M.ulcerans_Agy99 NGDTTYGGRWVVNPSGGLISKGHPLGATGLAQCCELTWQLRGTADRRQVD
*: .* :* .*** . ***:**:*: : *. *. *:
Mflv_1808|M.gilvum_PYR-GCK GAKTFGTLNFGGSTATTVSFVVGSTP------
Mvan_4939|M.vanbaalenii_PYR-1 GAKTFGTLNFGGSTATTVSFVVGRTP------
Mb0938c|M.bovis_AF2122/97 NAEAFGTLNFGGSTATTVSFVVSTTRGS----
Rv0914c|M.tuberculosis_H37Rv NAEAFGTLNFGGSTATTVSFVVSTTRGS----
MMAR_4613|M.marinum_M NATKFGTLNFGGSTATTVSFVVSTTKDA----
MSMEG_5608|M.smegmatis_MC2_155 AAKTFGTLNFGGSTATTVSFVVTAGKE-----
MAV_5079|M.avium_104 DPHTALTHNLGGRPGGCVSFVSIVSRTRRKRV
TH_3699|M.thermoresistible__bu EPHTALTHNLGGRPGGCVSFVSVVGRDR----
MAB_2951c|M.abscessus_ATCC_199 RVDAALQHNIGLGGAAVITAYQRAER------
MUL_2143|M.ulcerans_Agy99 NVTAALQHNIGLGGAAVVTAYQRAER------
*:* . ::