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M. bovis AF2122 / 97 Mb3553 (-)

annotation: acetyl-CoA acetyltransferase
coordinates: 3902744 - 3903928
length: 394

MAGKLAAVLGTGQTKYVAKRQDVSMNGLVREAIDRALADSGSTFDDIDAVVVGKAPDFFEGVMMPELFMA
DAMGATGKPLIRVHTAGSVGGSTGVVAASLVQSGKYRRVLALAWEKQSESNAMWALSIPVPFTKPVGAGA
GGYFAPHVRAYIRRSGAPAHIGAMVAVKDRLNGSRNPLAHLQQPDITLEKVMASQMLWDPIRFDETCPSS
DGACAVVVGDEEIADARLAQGHPVAWIHGTALRTEPLAFAGRDQVNPQAGRDAAAALWKAAGITSPIDEI
DAAEIYVPFSWFEPMWLENLGFAREGEGWKLTEAGETAIGGRLPVNPSGGVLSANPIGASGLIRFAEAAI
QVMGKAEARQVPGARKALGHAYGGGSQYFSMWVVGCEKPKQAAA
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb3553--100% (394)acetyl-CoA acetyltransferase
M. bovis AF2122 / 97Mb2813cltp12e-3029.90% (388) lipid-transfer protein
M. bovis AF2122 / 97Mb0938c-1e-2130.17% (401) acetyl-CoA acetyltransferase

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. gilvum PYR-GCKMflv_1536-0.087.31% (386) acetyl-CoA acetyltransferase
M. tuberculosis H37RvRv3523ltp30.0100.00% (394) acetyl-CoA acetyltransferase
M. leprae Br4923-----
M. abscessus ATCC 19977MAB_4169-0.086.75% (385) acetyl-CoA acetyltransferase
M. marinum MMMAR_5008ltp30.091.07% (392) lipid carrier protein or keto acyl-CoA thiolase Ltp3
M. avium 104MAV_0636-0.091.33% (392) acetyl-CoA acetyltransferase
M. smegmatis MC2 155MSMEG_5923-0.089.06% (384) acetyl-CoA acetyltransferase
M. thermoresistible (build 8)TH_0379-1e-11787.95% (224) PROBABLE LIPID CARRIER PROTEIN OR KETO ACYL-COA THIOLASE LTP3
M. ulcerans Agy99MUL_4082ltp30.090.82% (392) acetyl-CoA acetyltransferase
M. vanbaalenii PYR-1Mvan_5222-0.087.82% (386) acetyl-CoA acetyltransferase

CLUSTAL 2.0.9 multiple sequence alignment


Mb3553|M.bovis_AF2122/97            MAG----KLAAVLGTGQTKYVAKRQDVSMNGLVREAIDRALADSGSTFDD
Rv3523|M.tuberculosis_H37Rv         MAG----KLAAVLGTGQTKYVAKRQDVSMNGLVREAIDRALADSGSTFDD
MMAR_5008|M.marinum_M               MAGA-RAQLAAVLGTGQTKYVAKRQDVSMNGLVREAIDRALQDSGSTFDD
MUL_4082|M.ulcerans_Agy99           MAGA-RAQLAAVLGTGQTKYVAKRQDVSMNGLVREAIDRALQDSGSTFDD
MAV_0636|M.avium_104                MAGA-GPNIAAVLGTGQTKYVAKRQDVSMNGLVREAIDRALADSGCTFDD
MAB_4169|M.abscessus_ATCC_1997      -MGA-SKNLAAVIGTGQTKYVAKRQDVSMNGLVREAIDRAMTDAGVDWDD
Mflv_1536|M.gilvum_PYR-GCK          MASTTGKKLAAVLGTGQTKYVAKRKDVSMNGLVREAIDRALDDAGVTLAD
Mvan_5222|M.vanbaalenii_PYR-1       MAS---KKLAAVLGTGQTKYVAKRKDVSMNGLVREAIDRALEDAGVTLAD
MSMEG_5923|M.smegmatis_MC2_155      MAVN-----AAVLGTGQTKYVAKRTDVSMNGLVREAIDRALADSGSTMAD
TH_0379|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mb3553|M.bovis_AF2122/97            IDAVVVGKAPDFFEGVMMPELFMADAMGATGKPLIRVHTAGSVGGSTGVV
Rv3523|M.tuberculosis_H37Rv         IDAVVVGKAPDFFEGVMMPELFMADAMGATGKPLIRVHTAGSVGGSTGVV
MMAR_5008|M.marinum_M               IDAVVVGKAPDFFEGVMMPELFMADAMGASGKPLIRVHTAGSVGGSTGVV
MUL_4082|M.ulcerans_Agy99           IDAVVVGKAPDFFEGVMMPELFMADAMGASGKPLIRVHTAGSVGGSTGVV
MAV_0636|M.avium_104                IDAVVVGKAPDFFEGVMMPELFMADAVGATGKPLIRVHTAGSVGGSTGVV
MAB_4169|M.abscessus_ATCC_1997      IDAVVVGKAPDFFEGVMMPELFMADAIGATGKPMIRVHTAGSVGGSTGVV
Mflv_1536|M.gilvum_PYR-GCK          IDAVVVGKAPDFFEGVMMPELFMADATGATGKPLIRVHTAGSVGGSTAIV
Mvan_5222|M.vanbaalenii_PYR-1       IDAVVVGKAPDFFEGVMMPELFMADATGATGKPLIRVHTAGSVGGSTAIV
MSMEG_5923|M.smegmatis_MC2_155      IDAVVVGKAPDFFEGVMMPELFMADAVGATGKPLIRVHTAGSVGGSTAIV
TH_0379|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mb3553|M.bovis_AF2122/97            AASLVQSGKYRRVLALAWEKQSESNAMWALSIPVPFTKPVGAGAGGYFAP
Rv3523|M.tuberculosis_H37Rv         AASLVQSGKYRRVLALAWEKQSESNAMWALSIPVPFTKPVGAGAGGYFAP
MMAR_5008|M.marinum_M               AASLVQSGKYRRVLAMAWEKQSESNAMWALSIPIPFIKPVGAGAGGYFAP
MUL_4082|M.ulcerans_Agy99           AASLVQSGKYRRVLAMAWEKQSESNAMWALSIPIPFIKPVGAGAGGYFAP
MAV_0636|M.avium_104                AASLVQSGKYRRVLAMAWEKQSESNAMWALSIPVPFIKPVGAGAGGYFAP
MAB_4169|M.abscessus_ATCC_1997      AASLVQSGKYRRVLALAWEKQSESNAMWALSIPVPFSVPVGAGAGGYFAP
Mflv_1536|M.gilvum_PYR-GCK          AASLVQSGKYRRVLTMAWEKQSESNAMWALSIPVPFTKPVGAGAGGYFAP
Mvan_5222|M.vanbaalenii_PYR-1       AASLVQSGKYRRVLTMAWEKQSESNAMWALSIPVPFTKPVGAGAGGYFAP
MSMEG_5923|M.smegmatis_MC2_155      AASLVKSGRYRRVLTMAWEKQSESNAMWALSIPVPFTKPVGAGAGGYFAP
TH_0379|M.thermoresistible__bu      ---------------MSRESRSSAETRFRLLFFEVCHXXX----------
                                                   :: *.:*.::: : * :                  

Mb3553|M.bovis_AF2122/97            HVRAYIRRSGAPAHIGAMVAVKDRLNGSRNPLAHLQQPDITLEKVMASQM
Rv3523|M.tuberculosis_H37Rv         HVRAYIRRSGAPAHIGAMVAVKDRLNGSRNPLAHLQQPDITLEKVMASQM
MMAR_5008|M.marinum_M               HVRAYIRRSGAPSNIGAMVAVKDRLNGSRNPLAHLQQPDITLDKVMQSPM
MUL_4082|M.ulcerans_Agy99           HVRAYIRRSGAPSNIGAMVAVKDRLNGSRNPLAHLQQPDITLDEVMQSPM
MAV_0636|M.avium_104                HVRAYIRRSGAPTHIGAMVAVKDRLNGCRNPLAHLHQPDITLEKVMESPM
MAB_4169|M.abscessus_ATCC_1997      HVRAYIQRSKAPLDTGAMVAVKDRLNAAKNPLAHLHQPDITVEKVMSSPM
Mflv_1536|M.gilvum_PYR-GCK          HVRAYIRRSGAPTYIGAMVAVKDRLNGAKNPLAHLHQPDITLEKVMESPM
Mvan_5222|M.vanbaalenii_PYR-1       HVRAYIRRSGAPTHIGAMVAVKDRLNGAKNPLAHLHQPDITLEKVMESPM
MSMEG_5923|M.smegmatis_MC2_155      HVRAYIRRSGAPTHIGAMVAVKDRLNGAKNPLAHLHQPDITLEKVLSSQM
TH_0379|M.thermoresistible__bu      -------------------AVKDRLNGARNPLAHLQQPDITLEKVLDSQM
                                                       *******..:******:*****:::*: * *

Mb3553|M.bovis_AF2122/97            LWDPIRFDETCPSSDGACAVVVGDEEIADARLAQGHPVAWIHGTALRTEP
Rv3523|M.tuberculosis_H37Rv         LWDPIRFDETCPSSDGACAVVVGDEEIADARLAQGHPVAWIHGTALRTEP
MMAR_5008|M.marinum_M               LWDPIRYDETCPSSDGACAVVIGNEEIADTRVADGHPVAWIHATALRTEP
MUL_4082|M.ulcerans_Agy99           LWDPIRYDETCPSSDGACAVVVGNEEIADARVADGHPVAWIHATALRTEP
MAV_0636|M.avium_104                LWDPIRYDETCPSSDGACAVVIGNEEAAEARLAQGNPVAWIHATALRTEP
MAB_4169|M.abscessus_ATCC_1997      LWDPIRFDETCPSSDGACAIVVGDEQTADRRIKEGHAVAWVHATALRTEP
Mflv_1536|M.gilvum_PYR-GCK          LWDPIRYDETCPSSDGAAALVIGDEASADARVAEGHPVAWIHATALRTEP
Mvan_5222|M.vanbaalenii_PYR-1       LWDPIRYDETCPSSDGAAAMVIGDEASADARVAEGHPVAWIHATALRTEP
MSMEG_5923|M.smegmatis_MC2_155      LWDPIRFDETCPSSDGACAMVIGDDHIADARVAEGHPVAWIHATALRTEP
TH_0379|M.thermoresistible__bu      LWDPIRFDETCPSSDGACAVVIGDEATADARVADGHPVAWIHATALRTEP
                                    ******:**********.*:*:*::  *: *: :*:.***:*.*******

Mb3553|M.bovis_AF2122/97            LAFAGRDQVNPQAGRDAAAALWKAAGITSPIDEIDAAEIYVPFSWFEPMW
Rv3523|M.tuberculosis_H37Rv         LAFAGRDQVNPQAGRDAAAALWKAAGITSPIDEIDAAEIYVPFSWFEPMW
MMAR_5008|M.marinum_M               LAYSGRDQVSPQAGRDAAAALWKAAGITSPIDEIDAAEIYVPFSWFEPMW
MUL_4082|M.ulcerans_Agy99           LAYSGRDQVSPQAGRDTAAALWKAAGITSPIDEIDAAEIYVPFSWFEPMW
MAV_0636|M.avium_104                LAYAGRDQVSPQAGRDAAAALWKAAGIKSPIDEIDAAEIYVPFSWFEPMW
MAB_4169|M.abscessus_ATCC_1997      LDYTGRDRVNPQAGRDAAAALWKDAGITSPIDEIDVAEIYVPFSWFEPMW
Mflv_1536|M.gilvum_PYR-GCK          LAYAGRDQVNPQASRDAAAALWKSAGISSPIDEIDVAEVYVPFSWYEPMW
Mvan_5222|M.vanbaalenii_PYR-1       LAYAGRDQVNPQASRDAAAALWKSAGITSPIDEIDVAEVYVPFSWYEPMW
MSMEG_5923|M.smegmatis_MC2_155      LAYAGRDQVNPQAGRDAAKALWRDAGITSPIDEIDVAEVYVPFSWFEPMW
TH_0379|M.thermoresistible__bu      LAYAGRDQVNPQAGRDAAKALWEAAGITNPLEEIDVAEIYVPFSWFEPMW
                                    * ::***:*.***.**:* ***. ***..*::***.**:******:****

Mb3553|M.bovis_AF2122/97            LENLGFAREGEGWKLTEAGETAIGGRLPVNPSGGVLSANPIGASGLIRFA
Rv3523|M.tuberculosis_H37Rv         LENLGFAREGEGWKLTEAGETAIGGRLPVNPSGGVLSANPIGASGLIRFA
MMAR_5008|M.marinum_M               LENLGFMPEGEGWKLTEAGETAIGGRLPVNPSGGVLSSNPIGASGLIRFA
MUL_4082|M.ulcerans_Agy99           LENLGFMPEGEGWKLTEAGETAIGGRLPVNPSGGVLSSNPIGASGLIRFA
MAV_0636|M.avium_104                LENLGFAPEGEGWKLTEAGETKIGGRLPVNPSGGVLSSNPIGASGLIRFA
MAB_4169|M.abscessus_ATCC_1997      LENLGFAAEGEGWKLTQAGETAIGGKIPVNASGGVLSSNPIGASGLIRFA
Mflv_1536|M.gilvum_PYR-GCK          LESLGFAPEGEGWKLTEAGETAIGGRIPFNPSGGVLSSNPIGASGMIRFA
Mvan_5222|M.vanbaalenii_PYR-1       LESLGFAPEGGGWKLTEAGETAIGGRIPFNPSGGVLSSNPIGASGMIRFA
MSMEG_5923|M.smegmatis_MC2_155      LENLGFAPEGEGWKLTEAGETAIGGRIPFNPSGGVLSSNPIGASGMIRFA
TH_0379|M.thermoresistible__bu      LENLGFAAEGEGWRLTEAGETAIGGKLPVNPSGGVLSSNPIGASGMIRFA
                                    **.***  ** **:**:**** ***::*.*.******:*******:****

Mb3553|M.bovis_AF2122/97            EAAIQVMGKAEARQVPGARKALGHAYGGGSQYFSMWVVGCEKPKQAAA
Rv3523|M.tuberculosis_H37Rv         EAAIQVMGKAEARQVPGARKALGHAYGGGSQYFSMWVVGCEKPKQAAA
MMAR_5008|M.marinum_M               EAAIQVMGKGGDHQVPNARKALGHAYGGGSQYYSMWVVGADKP-----
MUL_4082|M.ulcerans_Agy99           EAAIQVMGKGGDHQVPNARKTLGHAYGGGSQYYSMWVVGADKP-----
MAV_0636|M.avium_104                EAAIQVMGKGGDHQVPGARKALGHAYGGGSQYYSMWVVGADKPAAEKV
MAB_4169|M.abscessus_ATCC_1997      EAAIQVMGKAGDHQVPGAKKALGHAYGGGSQYYSMWVVGSEKPAGKEQ
Mflv_1536|M.gilvum_PYR-GCK          ESAIQVMNKAGEHQVPNARKALGHAYGGGAQYFSMWVVGSDKPGDKPA
Mvan_5222|M.vanbaalenii_PYR-1       ESAIQVMGKAGEHQVPGARKALGHAYGGGAQYFSMWVVSADKPA----
MSMEG_5923|M.smegmatis_MC2_155      ESAIQVMGKAGEHQVQGARKALGHAYGGGSQYFSMWVVSSDKPAAKP-
TH_0379|M.thermoresistible__bu      EAAIQVMGKAGDHQVEGARKALGHAYGGGSQYFSMWVVGADKPVLR--
                                    *:*****.*.  :** .*:*:********:**:*****..:**