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MSFVLAMPEVLGSAATDLAALGSVLGAADAAAAATTTGIVAAVQDEVSAAIAALFSAHGRAYQVASAQAA AVHAQFVEALSAGAGAYASAEAAGAAVLANPAQSVQQDLLAAVNAQSVALTGRPLIGNGANGAPGTGANG APGGWLLGNGGAGGSAAAGSGLPGGAGGAAGLFGTGGAGGAGGSSTVGDGGAGGAGGSGGWLLGTGGVGG VGGLGAGAGGAGGVGGAGGLLGAGGHGGAGGLGAVTGGVGGAGGAGGLLAGLLAGPGGAGGTGGRGFLND GGVGGAGGNAGLLFGAGGTGGSGGAGLGGDGGAGGAGGNAGVLFGNAGSGGTGGFGDTDGGAGGAGGDAG WLGSGGVGGAGGFGETGDGGVGGAGGKAGLLIGNGGAGGAGVLIGNGGNAGIGGTGPTAGDTGAGGISGL LLGADGFNAPASASPLHTLKQQALAAINAPTQTLTGRPLIGNGTPGAVGSGATGAPGGWLLGDGGAGGSG AAGSGAPGGAGGAAGLWGTGGAGGAGGWLLGDGGAGGIGGASTVLGGTGGGGGVGGLWGAGGAGGAGGTG LVGGDGGAGGAGGTGGLLAGLIGAGGGHGGTGGLNTNGDGGVGGAGGNAGMLAGPGGAGGAGGDGENLDT GGDGGAGGSAGLLFGSGGAGGAGGFGFLGGDGGAGGNAGLLLSSGGAGGFGGFGTAGGVGGAGGNAGWLG FGGAGGIGGIGGNANGGAGGNGGTGGQLWGSGGAGGEGGAALSVGDTGGAGGVGGSAGLIGTGGNGGNGG TGANAGSPGTGGAGGLLLGQNGLNGLP
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0767 | PE_PGRS9 | - | 100% (797) | PE-PGRS family protein |
| M. bovis AF2122 / 97 | Mb0286c | PE_PGRS3 | 0.0 | 57.33% (900) | PE-PGRS family protein |
| M. bovis AF2122 / 97 | Mb0768 | PE_PGRS10 | 0.0 | 55.79% (941) | PE-PGRS family protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. gilvum PYR-GCK | Mflv_5091 | - | 1e-137 | 45.74% (728) | triple helix repeat-containing collagen |
| M. tuberculosis H37Rv | Rv0746 | PE_PGRS9 | 0.0 | 88.19% (830) | PE-PGRS family protein |
| M. leprae Br4923 | MLBr_01183 | - | 2e-12 | 39.56% (91) | hypothetical protein MLBr_01183 |
| M. abscessus ATCC 19977 | MAB_4284c | - | 1e-44 | 36.16% (437) | hypothetical protein MAB_4284c |
| M. marinum M | MMAR_1195 | - | 0.0 | 63.39% (885) | PE-PGRS family protein, PE_PGRS9_4 |
| M. avium 104 | MAV_4827 | - | 8e-24 | 42.25% (187) | hypothetical protein MAV_4827 |
| M. smegmatis MC2 155 | MSMEG_0868 | - | 1e-112 | 36.28% (962) | hypothetical protein MSMEG_0868 |
| M. thermoresistible (build 8) | TH_3810 | - | 5e-40 | 41.20% (284) | PUTATIVE - |
| M. ulcerans Agy99 | MUL_3062 | - | 0.0 | 62.27% (864) | PE-PGRS family protein |
| M. vanbaalenii PYR-1 | Mvan_1264 | - | 1e-136 | 45.30% (755) | triple helix repeat-containing collagen |
CLUSTAL 2.0.9 multiple sequence alignment
Mb0767|M.bovis_AF2122/97 --------------------------------------------------
Rv0746|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_1195|M.marinum_M --------------------------------------------------
MUL_3062|M.ulcerans_Agy99 --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_1264|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_0868|M.smegmatis_MC2_155 MHERLRERAGGVRKTLSDFAEGAGLKPSDTDDTRSPLRKPKFPAALAPES
TH_3810|M.thermoresistible__bu --------------------------------------------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 --------------------------------------------------
MAV_4827|M.avium_104 --------------------------------------------------
Mb0767|M.bovis_AF2122/97 ------------------MSFVLAMPEVLGSAATDLAALGSVLG------
Rv0746|M.tuberculosis_H37Rv ------------------MSFVLAMPEVLGSAATDLAALGSVLG------
MMAR_1195|M.marinum_M ------------------MSFVIAVPEVVGSAASEVAGIGSALG------
MUL_3062|M.ulcerans_Agy99 ------------------MAFVLAVPDMVAEAAADLAGVGSVID------
Mflv_5091|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_1264|M.vanbaalenii_PYR-1 -------------------MMFLAPPGGPGPISAAIQLTSTGSEATEP--
MSMEG_0868|M.smegmatis_MC2_155 PLPDLKPRWERPTTAPDSETPSITQPQGRDTAADPAEQQATSTNTTDQPT
TH_3810|M.thermoresistible__bu --------------------------------------------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 ---------------MSIIDFILNLFRDPVEAASYVADPEAALAN-----
MAV_4827|M.avium_104 ------------------MNIVLGVSMAPSSIQMVVLEGEYADG------
Mb0767|M.bovis_AF2122/97 ---------------------------------------AADAAAAATTT
Rv0746|M.tuberculosis_H37Rv ---------------------------------------AADAAAAATTT
MMAR_1195|M.marinum_M ---------------------------------------EATAAAAAPTV
MUL_3062|M.ulcerans_Agy99 ---------------------------------------AANTAAAGSTT
Mflv_5091|M.gilvum_PYR-GCK --------------------------------------MVTFGGGATPTP
Mvan_1264|M.vanbaalenii_PYR-1 ------------------------------------WYVVSFGGSGAPTP
MSMEG_0868|M.smegmatis_MC2_155 SDSLGAQPTAQVARQVQAPATDPAPAAPSLRPISGLLSVVTLGTTLIPNA
TH_3810|M.thermoresistible__bu --------------------------------------------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 ---------------------------------------AGLSAVSAAQV
MAV_4827|M.avium_104 ---------------------------------------ATVEEDAIDVT
Mb0767|M.bovis_AF2122/97 GIVAAVQDEVSAAIAALFSAHGRAYQVASAQAAAVHAQFVEALSAGAGAY
Rv0746|M.tuberculosis_H37Rv GIVAAAQDEVSAAIAALFSAHGRAYQVASAQAAAVHAQFVEALSAGAGAY
MMAR_1195|M.marinum_M QVLAAAQDEVSQAIAAVFSTHAQAYQAASAQAQSLGQRFAQALAAGAGSY
MUL_3062|M.ulcerans_Agy99 GIVAAAEDEVSAAIAALFSGHGQAYQQISTRVAEFHAQFERVFAAGVQAY
Mflv_5091|M.gilvum_PYR-GCK ----------------------------------------TSLGAAAVDL
Mvan_1264|M.vanbaalenii_PYR-1 ----------------------------------------NNLAASLVDL
MSMEG_0868|M.smegmatis_MC2_155 PTEPADMPGVWAVMAWARRQPMYSDPAMRTTVNPQAQLPVPTVASAVLDP
TH_3810|M.thermoresistible__bu --------------------------------------------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 GAVMPVVAESVASNYGYQSQWVNTGNPIHDLSGNLQNYYAAQPDGPSILS
MAV_4827|M.avium_104 GADDAATASAPDRVISAILGTREGAADAGLQLSSIGVTWTDQLEAAALRD
Mb0767|M.bovis_AF2122/97 AS-----------------------AEAAGAAVLANPAQSVQQDLLAAVN
Rv0746|M.tuberculosis_H37Rv AS-----------------------AEAAGAAVLANPAQSVQQDLLAAVN
MMAR_1195|M.marinum_M SS-----------------------AEAAAAAVLANPAQVVSGDLLAAIN
MUL_3062|M.ulcerans_Agy99 SG-----------------------AEAANASFLQDPLQTA----LNATN
Mflv_5091|M.gilvum_PYR-GCK S------------------------GTSCG----------LICNGQDGTG
Mvan_1264|M.vanbaalenii_PYR-1 S------------------------GTSCG----------LICNGQDGTG
MSMEG_0868|M.smegmatis_MC2_155 TQIVNWLIYQPLHAAGQQFWVVSPIGSTLGGVINTISGQYLIGNGINGTA
TH_3810|M.thermoresistible__bu --------------------------------------------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 PS----------------------LLSPRDNDFLSHNDTDFASHNPIASG
MAV_4827|M.avium_104 AL------------------------AARRIDNVMLVSAFLAAAALAQNV
Mb0767|M.bovis_AF2122/97 AQSVALTGRPLIGNGANGAPG-----TGANGAPGGWLLGNGGAGGSAAAG
Rv0746|M.tuberculosis_H37Rv AQSVALTGRPLIGNGANGAPG-----TGANGAPGGWLLGNGGAGGSAAAG
MMAR_1195|M.marinum_M APVLSLTGRPLIGNGANGAPG-----TGANGAAGGWLLGDGGAGGSGAP-
MUL_3062|M.ulcerans_Agy99 KPVQDLTGRPLVGNGANGVPG-----TGANGAAGGWLLGNGGAGGSGAA-
Mflv_5091|M.gilvum_PYR-GCK QN-----GGILFGNGGSGWNSDVVGMDGGNGGNGGLFGGNGGNGGNGLGG
Mvan_1264|M.vanbaalenii_PYR-1 QN-----GGILFGNGGSGWNSEIAGVSGGNGGNAGLFGGNGGNGGNGLGS
MSMEG_0868|M.smegmatis_MC2_155 DNPNGGTGGLLFGDGGHGYDGSAAGLAGGNGGNAGLFG-NGGNGGVGWAG
TH_3810|M.thermoresistible__bu ------------------------------------------------VD
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 NQVMSPSGNVDSFNRGPLLDLSFGDLQFGNRDTTAIGDGAVAVGGSNSGP
MAV_4827|M.avium_104 GGAMGYERTAVLLVEPDTATLAVVETSDGSIPDVYKQQIRAESYGDAAGQ
Mb0767|M.bovis_AF2122/97 -SGLPGGAGGAAGLFGTGGAGGAGGSS---TVGDGG--AGGAGGSGGWLL
Rv0746|M.tuberculosis_H37Rv -SGLPGGAGGAAGLFGTGGAGGAGGSS---TVGDGE--AGGAGGSGGWLL
MMAR_1195|M.marinum_M --GMAGGNGGAAGLWGTGGAGGAGGRT---FNGDGG--NGGAGGAGGWLM
MUL_3062|M.ulcerans_Agy99 --GQAGGDGGAAGLIGAGGAGGAGGNSPLRNTANGG--NGGTGGAGGLLF
Mflv_5091|M.gilvum_PYR-GCK GNGGNGGNAGAFALFGNGGNGGNGGVGVVGATGAVG--APGVAGATGATG
Mvan_1264|M.vanbaalenii_PYR-1 GDGGNGGDAGLFSLFGRGGNGGNGGVGIAGATGAVG--APGVAGATGATG
MSMEG_0868|M.smegmatis_MC2_155 LDGGNGGSGG--LLMGIGGAGGAGGVGADGTSAHVDGGTGGTGGTGGGTG
TH_3810|M.thermoresistible__bu GDGGSGGRTGLFSKLSRGGDGGDGGLG-------------GNGGHGGGTG
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 IASGQGSTAVNGDVRDSNIINADHGSNVGVDQSQTRVGGDYTNVSGHGSA
MAV_4827|M.avium_104 LSAMVAGLEKLESLPGGLLLVGSGVDVAPLKQVLQTTTFLDVSVAEEPET
Mb0767|M.bovis_AF2122/97 GTGGVGGVGGLG----AGAGGAGGVGGAGGLLGAGGHGGAG---------
Rv0746|M.tuberculosis_H37Rv GTGGVGGVGGLG----AGAGGAGGVGGAGGLLGAGGHGGAG---------
MMAR_1195|M.marinum_M GTGGAGGAGGAGGFSGTGDGGSGGAGGAGGLLGGGGVGGAG---------
MUL_3062|M.ulcerans_Agy99 GPGGVGGAGGAS----FLTGGTGGDGGAGGLFGAGGLGGVG---------
Mflv_5091|M.gilvum_PYR-GCK VTSGVVGGNGED----AVGYGATGAAGAAGAAGAAGAAG-----------
Mvan_1264|M.vanbaalenii_PYR-1 VTSNVTGGNGAD----AVGYGATGAAGAAGAAGAAGKAG-----------
MSMEG_0868|M.smegmatis_MC2_155 GTGGIGGTGGGL----FGLLGHSGSTGAAGAAGNGGDGGNGGFGYVLIAG
TH_3810|M.thermoresistible__bu IIS------------------------LLSLAGNGGNGG-----------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 DIDKSVTVVDDHSQRNTTNINDSFNTDRSTNIGSGNTTN-----------
MAV_4827|M.avium_104 ALARGAALAAAN------APLFASSTAALAYAQDPGTG------------
Mb0767|M.bovis_AF2122/97 ---GLG-AVTGGVGGAGGAGGLL---------------------------
Rv0746|M.tuberculosis_H37Rv ---GLG-AVTGGVGGTGGAGGLL---------------------------
MMAR_1195|M.marinum_M ---GFSNGGTGGVGGTGGAGGVLSGVVGAGGGHGGTGGYGAFDGGAGGVG
MUL_3062|M.ulcerans_Agy99 ---GSG--NVGGNGGAGGAGGLLAGLVGAGGGDGGSGGLG-AAGGDGGNG
Mflv_5091|M.gilvum_PYR-GCK ---AVGSAGAAGEAGETGTWG--NAGLPGKAGDAGGAG------------
Mvan_1264|M.vanbaalenii_PYR-1 ---AVGSAGTAGSAGAPGVWG--NAGLPGAAGAAGGAG------------
MSMEG_0868|M.smegmatis_MC2_155 PNVTVGSETRGGTGGAGGTGGQSTAAGPGKGGGGGGGGGGAILIGANGGT
TH_3810|M.thermoresistible__bu ----NGYRTTDNNALDGGHGG-----------------------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 --TEIGSHNQANIGTSTSAGG-----------------------------
MAV_4827|M.avium_104 ---AVDQYSLPDYLYVPVDPE-----------------------------
Mb0767|M.bovis_AF2122/97 --AGLLAGPGGAGGTGGRGFLN-DGGVGGAG----------------GNA
Rv0746|M.tuberculosis_H37Rv --AGLLAGPGGAGGTGGRGFLN-NGGVGGAG----------------GNA
MMAR_1195|M.marinum_M GHAGLLGGPGGAGGDGGDTFGGGSGGAGGAG----------------GDG
MUL_3062|M.ulcerans_Agy99 GRAGLFGGAGGAGGMG--ATGGHSGGDGGAG----------------GDA
Mflv_5091|M.gilvum_PYR-GCK ----AVGAAGAAG------TVGTAGATGGTG---------------TGAN
Mvan_1264|M.vanbaalenii_PYR-1 ----AIGTAGVAG------AAGTAGATGGTG---------------VGGN
MSMEG_0868|M.smegmatis_MC2_155 VDGHAIGGNGGNGGNGSTTAAGGNGGTGGTGRVIAEGTGSTAEGTATGGD
TH_3810|M.thermoresistible__bu ----------------------------------------------NGGN
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 ----------------SAAVGGNAGLAGNAG---------------LAGN
MAV_4827|M.avium_104 ----------------------------------------------PGDD
Mb0767|M.bovis_AF2122/97 GLLFGAGGTGGSGGAGLGGD------------GGAGGAGGNAGVLFGNAG
Rv0746|M.tuberculosis_H37Rv GLLFGAGGTGGSGGAGLGGD------------GGAGGAGGNTGVLFGNAG
MMAR_1195|M.marinum_M GWAFGSGGTGGTG--GYGGA------------GGAGGSGGDAGLLFSNGG
MUL_3062|M.ulcerans_Agy99 GLLFGTGGAGGAGGHAFDGD------------GGAGGAGGNAGLMFSSGG
Mflv_5091|M.gilvum_PYR-GCK GGAGGVGGVGGTGAAG--------------AAGGAGGLGETGTTGGAGGV
Mvan_1264|M.vanbaalenii_PYR-1 GGAGQAGGIGGTGAAG--------------AAGQAGTAGETGVTGGVGGI
MSMEG_0868|M.smegmatis_MC2_155 GGHSTGTGIGGNGGIGSVYAYGNNGAVSGTATGGRGGDGIDGGTGGAGGM
TH_3810|M.thermoresistible__bu VGFFSLFNLGG--------------------AGGWGGSGVDG--------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 AGLAGNAGLAGNAGLAGNAG----------LAGNAGLAGNAGLAGNAGLA
MAV_4827|M.avium_104 ELAYSAVGEEDAESPTVVIEK----------LFLPEDSEPRRRPVLLVGS
Mb0767|M.bovis_AF2122/97 SGGTGGFGDTDGGAGGAGGDAGWLGSGGVGGAGG----------------
Rv0746|M.tuberculosis_H37Rv SGGTGGFGDTDGGAGGAGGDAGWLGSGGVGGAGG----------------
MMAR_1195|M.marinum_M AGGTGGFGET-GGEGGAGGGAGWLGDGGAGGTGG----------------
MUL_3062|M.ulcerans_Agy99 SGGVGGAGSIDGGAGGAGGDAGWLGGGGAGGAGG----------------
Mflv_5091|M.gilvum_PYR-GCK GGQ--GTAGGTGGVGGIGGAGSTGAVGGVGGKG----IQGGQG-------
Mvan_1264|M.vanbaalenii_PYR-1 GGQ--GTEGGTGGVGGVGGVGATGGAGGVGGKG----IQGGQG-------
MSMEG_0868|M.smegmatis_MC2_155 GEIYSGADGEATGISAGGDGGSATGADSLGGRGGTSWVQAGYGPTTGGKA
TH_3810|M.thermoresistible__bu -------------VDVVGGNP-----------------------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 GNAGLAGNAGLAGNAGLAGNAGLAGNAGLAGNAG----------------
MAV_4827|M.avium_104 GLAVVGISAVLALEIALAIGIRTTGTVALQPTPN----------------
Mb0767|M.bovis_AF2122/97 --------FGETGDGGVGGAGGKAGLLIG---------------------
Rv0746|M.tuberculosis_H37Rv --------FGETGDGGVGGAGGKAGLLIG---------------------
MMAR_1195|M.marinum_M --------AANIGSGGDGGGGGTGGTLLG---------------------
MUL_3062|M.ulcerans_Agy99 --------FGTISDGGAGGRGGGGGQLLG---------------------
Mflv_5091|M.gilvum_PYR-GCK ------LQGGKGGDGGAGGKGGDADSMGS------------------AGA
Mvan_1264|M.vanbaalenii_PYR-1 ------LQGGQGGDGGTGGTGGDATSMGE------------------AGA
MSMEG_0868|M.smegmatis_MC2_155 SGTAKAGHGGKASDGGKGGNGGDALVMAAGATGVATGNTAIGGNGGAASA
TH_3810|M.thermoresistible__bu -------------DGGTPG------------------------------A
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 ----------LAGNAGLAGNAGLAGN------------------------
MAV_4827|M.avium_104 ------QHLIVPTEQAPAPPPVQASAPQP-----------------KISV
Mb0767|M.bovis_AF2122/97 NGGAGGAG------------------------------VLIGN-------
Rv0746|M.tuberculosis_H37Rv NGGAGGAGGQGAVTGGTG--------------GAGGDGVLIGN-------
MMAR_1195|M.marinum_M NGGAGGAGGHGPTDGGAG--------------GTGGNAVVVGN-------
MUL_3062|M.ulcerans_Agy99 NGGAGGAGGQGGNDGGAG--------------GLGGNGVLIGN-------
Mflv_5091|M.gilvum_PYR-GCK TGGKGGNGGNGGRGGLFG---------------KGGNAGNGAD-------
Mvan_1264|M.vanbaalenii_PYR-1 TGGKGGNGGNGGRGSLFG---------------RGGNAGNGGN-------
MSMEG_0868|M.smegmatis_MC2_155 NGAVGGNGGFTNIAAIHGSITDSSATSGHGGAAQGGNGGNGGNGWVQAYD
TH_3810|M.thermoresistible__bu HGESHTPGVYTDRQ------------------------------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 -AGLAGNAGLAGNAGLAG--------------------------------
MAV_4827|M.avium_104 PEPVAAPKPLSPPVAAPLP-------------------------------
Mb0767|M.bovis_AF2122/97 ------------------GGNAGIGGTGPTAGDTGAGGISGLLLGADG--
Rv0746|M.tuberculosis_H37Rv ------------------GGNAGIGGTGPTAGDTGAGGISGLLLGADG--
MMAR_1195|M.marinum_M ------------------GGNGGIGGTGPTTGTTGAGGIGGLLLGLDG--
MUL_3062|M.ulcerans_Agy99 ------------------GGNGGVGGVGETPGGDGGGGISGLLLGADG--
Mflv_5091|M.gilvum_PYR-GCK ---------------GGTGGAGGAGGTGG-TGGAGGTGG-----------
Mvan_1264|M.vanbaalenii_PYR-1 ---------------GGTGGNGGNGGTGG-TGGNGGTGG-----------
MSMEG_0868|M.smegmatis_MC2_155 PNGPAGTTIDKGKAAGGNGGDGGFNGTGGATGGRGGDGAGASVWKANGQH
TH_3810|M.thermoresistible__bu -------------------GEDGEDGTGTGIGGRGGNGG-----------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 --------------------NAGLAGNAAVAGNAAVAGN-----------
MAV_4827|M.avium_104 --------------------AAPPPAAPPLPEAPPIPAAPPVVPVPVVVP
Mb0767|M.bovis_AF2122/97 ---FNAPASASPLHTLKQQALAAINAPTQTLTGRPLIGNGTPGAVGSGAT
Rv0746|M.tuberculosis_H37Rv ---FNTPASASPLHTLKQQALAAINAPTQTLTGRPLIGNGTPGAVGSGAT
MMAR_1195|M.marinum_M ---YNAPTSTSPIHVAQQQALVAINSPVQDLTGRPLIGNGTPAPAGSGAD
MUL_3062|M.ulcerans_Agy99 ---FNAPAGSSPVHALQQQALAAINAPVQELTGRPLIGNGLPGSAGSGAA
Mflv_5091|M.gilvum_PYR-GCK ------TGGTGGIGGAGSTGGTGGTGGTGGTGGTGGTG-GTGGTGGTGGT
Mvan_1264|M.vanbaalenii_PYR-1 ------TGGTGGIGGAGSTGGTGGTGGTGGTGGTGGTG-GTGGTGGTGGT
MSMEG_0868|M.smegmatis_MC2_155 STGQTDTGGNGGRGGDGGTFVNAGANGNGGAGGAGGVSEGEGGTGGHGGD
TH_3810|M.thermoresistible__bu -----SSSGTHPMAEDG--------EHVKALDGRPGLD---GGNGSHGGN
MLBr_01183|M.leprae_Br4923 ---------MPLFLNAEPQALTAAANTLEGLSAATVASNAAAAQLTTEIA
MAB_4284c|M.abscessus_ATCC_199 ----AAVAGNAAVGGVLNTGVSGAIGGSSHVGG--AINESLGGSGSVGGS
MAV_4827|M.avium_104 PVPVPVPVRIPVPDPVSPPQLLAPPRLSVPQPVQPPVRVPQPPSPPQVGG
Mb0767|M.bovis_AF2122/97 GAPGG--WLLGDGGAGGS--GAAGSGAPGGAGGAAG---------LWGTG
Rv0746|M.tuberculosis_H37Rv GAPGG--WLLGDGGAGGS--GAAGSGAPGGAGGAAG---------LWGTG
MMAR_1195|M.marinum_M GTPGG--WLLGDGGAGGS--AVAGSDGAGGSGGAAG---------LWGTG
MUL_3062|M.ulcerans_Agy99 GAPGG--WLLGDGGAGGS--AAATPGAAGGAGGAAG---------LVGAG
Mflv_5091|M.gilvum_PYR-GCK GGKGGTGGTGGAGGTG----GDGGTGGTGGTGGTG---------GTGGTG
Mvan_1264|M.vanbaalenii_PYR-1 GGKGGTGGTGGDGGTG----GTGGTGGTGGTGGTG---------GTGGTG
MSMEG_0868|M.smegmatis_MC2_155 GGRGGDGALGGNGGTGGVGLGNGGKGGNGGNGGNGGTYVDPSHTGAGGNG
TH_3810|M.thermoresistible__bu GGHGGRGGFLGIGGSG-------GWGGHGGNGGD-----------TDADG
MLBr_01183|M.leprae_Br4923 PPAADDVSILLAHFFS-------GHGRQ-----------------YQAHA
MAB_4284c|M.abscessus_ATCC_199 TAVGGGAHTGVGGGVSTG----VGVGSHVGGGISES---------LGGSG
MAV_4827|M.avium_104 TVPQSPPQHQTPPGEGTPP-KPDGPGNYGGGHVP-----------TPGAG
. . . . .
Mb0767|M.bovis_AF2122/97 GAG---------------------GAGGWLLGDGGAGGIGGASTVLG---
Rv0746|M.tuberculosis_H37Rv GAGGAGG-----SSAGGGGAGGAGGAGGWLLGDGGAGGIGGASTVLG---
MMAR_1195|M.marinum_M GTGGAGAR----STTGNGGAGGAGGAGGWLSGDGGTGGTGGAATFNG---
MUL_3062|M.ulcerans_Agy99 GAGGAG-----------------ANTGISNPGFGGAGGAGGAGAGAGG--
Mflv_5091|M.gilvum_PYR-GCK GTGGAG-----------DGTGGTGGTGG----TGGQGGQGGQGG------
Mvan_1264|M.vanbaalenii_PYR-1 GTGGAG-----------DGLGGTGGTGG----TGGFGGQGGQGG------
MSMEG_0868|M.smegmatis_MC2_155 GNGGAGRIRVNNGTATGTATGGNGGNGGNGDADGHRGGKGGDGGEALIRA
TH_3810|M.thermoresistible__bu GNGGDG---------------GNGGSAG----------------------
MLBr_01183|M.leprae_Br4923 SQGATN--------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 SVGGSTAVG-----------------------------------------
MAV_4827|M.avium_104 GSGGSG--------------------------------------------
. *
Mb0767|M.bovis_AF2122/97 ----------GTGGGGG---VGGLWGAGGAGG------------------
Rv0746|M.tuberculosis_H37Rv ----------GTGGGGG---VGGLWGAGGAGG------------------
MMAR_1195|M.marinum_M ----------ATGGNGGDAGNGGLFGAGGNGG------------------
MUL_3062|M.ulcerans_Agy99 ----------GVGEAGG---AGGLLGAGGTGG------------------
Mflv_5091|M.gilvum_PYR-GCK -----------TGGTGG---QGG-LGGGGGTG------------------
Mvan_1264|M.vanbaalenii_PYR-1 -----------TGGTGG---QGG-LGGVGGTG------------------
MSMEG_0868|M.smegmatis_MC2_155 TVIGSNASGTATGGDGG---NGGTLGATNGTGGAATIVAYNVVQANPQAS
TH_3810|M.thermoresistible__bu -----------RGGTGG---LRGVFGINGGNG------------------
MLBr_01183|M.leprae_Br4923 --------------------HQDLIQSLLTSS------------------
MAB_4284c|M.abscessus_ATCC_199 -----------GGAHTG---VGGGVSTGVGVG------------------
MAV_4827|M.avium_104 ---------------------GGHVPTPGAGG------------------
. .
Mb0767|M.bovis_AF2122/97 ------AGGTG--LVG-GDGGAGGAGGTG------GLLAGLIGAGGGHGG
Rv0746|M.tuberculosis_H37Rv ------AGGTG--LVG-GDGGAGGAGGTG------GLLAGLIGAGGGHGG
MMAR_1195|M.marinum_M ------AGGAG--LGNPGFGGAGGNGGAG------GLLSGLVGAGGGHGG
MUL_3062|M.ulcerans_Agy99 ------GGGVAPSLVDGGTGGAGGAGGAG------GLFGGIFGAGGGDGG
Mflv_5091|M.gilvum_PYR-GCK -----GQGGTGGTGGQGGTGGTGGTGGTG--------GTGGAGGDGGLGG
Mvan_1264|M.vanbaalenii_PYR-1 -----GTGGTGGTGGQGGTGGTGGTGGTG--------GTGGAGGDGGLGG
MSMEG_0868|M.smegmatis_MC2_155 GTATDGHGGSGINGGHGGNGGQGTIEANGPSAVASGIGAGGNGGDGIDGG
TH_3810|M.thermoresistible__bu ------RAGLGGRGXXXXGGGVGAAVRSG---------------NGVFSG
MLBr_01183|M.leprae_Br4923 ----------------SAYAGTETANHDSL--------------------
MAB_4284c|M.abscessus_ATCC_199 -----SHVGGGISESLGGSGSVGGSTAVG---------------GGAHTG
MAV_4827|M.avium_104 -----SGGSGGGHVPTPGTGGPGGTGGSG----------------GGHVP
.. .
Mb0767|M.bovis_AF2122/97 TGGLNTN-------GDGGVGGAGGNAGMLAG--PGGAGGAGGDG----EN
Rv0746|M.tuberculosis_H37Rv TGGLSTN-------GDGGVGGAGGNAGMLAG--PGGAGGAGGDG----EN
MMAR_1195|M.marinum_M AGGLGVSPSTPAALAGGGIGGAGGDAGLLGG--AGGAGGTGGSGAF--DV
MUL_3062|M.ulcerans_Agy99 AGGFTGG-----IDGAGGVGGAGGNTGLLGG--PGGSGGSGGDGIAKLGF
Mflv_5091|M.gilvum_PYR-GCK LGGFGGSGGTGGQGGLGGPGGSTGGAGGAGG--QAGTAGKGGLFG----G
Mvan_1264|M.vanbaalenii_PYR-1 LGGFGGVGGTGGQGGQGGPGGSTGGAGGAGG--QAGVAGKGGLFG----G
MSMEG_0868|M.smegmatis_MC2_155 LGGNGGDGVVNTTANAANPGSATGTATGGDGGKATGTASQGGNGGPSWVQ
TH_3810|M.thermoresistible__bu GGGTPSAGFGVPTTIQFPAGSCTSRAVSREG-------------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 VGGGVNTGVGVGSHVGGGISESLGGSGSVGG-------------------
MAV_4827|M.avium_104 TPG------------AGTPGGSGGGHLPFPG-------------------
Mb0767|M.bovis_AF2122/97 LDTGGDGGAGGSAGLLFGSGGAGGAGGFGFLG---------------GDG
Rv0746|M.tuberculosis_H37Rv LDTGGDGGAGGSAGLLFGSGGAGGAGGFGFLG---------------GDG
MMAR_1195|M.marinum_M TSTGGTGGAGGNAGFLFGSGGIGGPGGFAVAAS--------------GNG
MUL_3062|M.ulcerans_Agy99 NVDGGAGGAGVNGGFLFGSGGTGGFGGVGGVGTS---------TGIGGAG
Mflv_5091|M.gilvum_PYR-GCK SGSAGKAGATGAAGASGGKGAQGATGAQGATG------AQGATG-ATGAA
Mvan_1264|M.vanbaalenii_PYR-1 SGSAGTAGVTGASGASGGKGAQGATGAQGATG------AQGATG-ATGAS
MSMEG_0868|M.smegmatis_MC2_155 SGYGSTLGGNATGTATAGKGGEASNGGVAGNGGNALVMAAGTTGVATGNT
TH_3810|M.thermoresistible__bu -----IMPSSRAASARAG---------------------------AACAS
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 --STAVGGGAHTSAINDALGGSGSVGGSTAVG---------------GGA
MAV_4827|M.avium_104 ---AGSTPGGSGGGHLPTPGAGTPGGGLGGFG---------------GGH
Mb0767|M.bovis_AF2122/97 GAGGNAGLLLSSGGAGGFGGFGTAG----GVGGAGGNAGWLGFGGAGGIG
Rv0746|M.tuberculosis_H37Rv GAGGNAGLLLSSGGAGGFGGFGTAG----GVGGAGGNAGWLGFGGAG---
MMAR_1195|M.marinum_M GQGGHAGLLWSSGGAGGAGAFSVSGP--AGAGGHGGDAGWLGNGGAGGTG
MUL_3062|M.ulcerans_Agy99 GRGGNAGLLFSDAGVGGFGGF----------GGTGGNAGWLGSGGSGGAG
Mflv_5091|M.gilvum_PYR-GCK GKAGATGAAGAAGAAGSAG-----------TTGAQGSAGTNGA-NGANGS
Mvan_1264|M.vanbaalenii_PYR-1 GAQGSAGSAGSAGVAGSAG-----------TTGAQGSAGTNGA-NGANGS
MSMEG_0868|M.smegmatis_MC2_155 ATGGDGGAATTAGATGGAGGFSNIAAIHGAITDSTAISGHGGAGNGGNGG
TH_3810|M.thermoresistible__bu STSRSRRSFCCSRA------------------------------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 HTSAINESMNSSINASHSSSMN----------------------------
MAV_4827|M.avium_104 APAPGGGLGGGGGHAPAPG-------------------------------
Mb0767|M.bovis_AF2122/97 GIGGNANGGAGGNGGTGGQLWGSGGAGGEGGAALSVGDT--GGAGGVGGS
Rv0746|M.tuberculosis_H37Rv ---------------------------------------------GVGGS
MMAR_1195|M.marinum_M GISRNGNGGDGGAGGSGGELLGVGGAGGQGGQANAGGGTGTGGEGGDGGD
MUL_3062|M.ulcerans_Agy99 G-GSNGDGGAGGTGGSGGQIVGDGGAGGAGGQGDLLAAGGSGGDGGQGGD
Mflv_5091|M.gilvum_PYR-GCK QGAAGKAGATGTTGATG--------AAGEDGDAGSGGSG-INGGAGGAGG
Mvan_1264|M.vanbaalenii_PYR-1 QGAAGKAGATGTTGATG--------AAGDAGDPGSEAVD-INGGAGGAGG
MSMEG_0868|M.smegmatis_MC2_155 KGADGWVQAYDPAGPVGSKIANSSAVAGNGGDGGVNGTGGASGGDGGNGG
TH_3810|M.thermoresistible__bu --------------------------------------------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 --------------------------------------------------
MAV_4827|M.avium_104 --------------------------------------------------
Mb0767|M.bovis_AF2122/97 ------------AGLIGTGGNGGNGGTGAN--------AGSPGTGGAGGL
Rv0746|M.tuberculosis_H37Rv ------------AGLIGTGGNGGNGGTGAN--------AGSPGTGGAGGL
MMAR_1195|M.marinum_M ------------AGLIGDGGNGGNAGTDTDGTP-----TGDPGTGGTGGT
MUL_3062|M.ulcerans_Agy99 ------------AVLIGTGGNGGNGASGVL--------AGIGGDGGSRGL
Mflv_5091|M.gilvum_PYR-GCK -----------AGGEGGEGGDGGKGGAGAE--------GGAGGGGGAGGS
Mvan_1264|M.vanbaalenii_PYR-1 -----------AGGEGGEGGAGGAGGDGSE--------GGAGGSGGAGGS
MSMEG_0868|M.smegmatis_MC2_155 NTSVWKSGGQTADGEHNTGGNGGNGGDGSEPGPGGNGAGGAGGNGGTGGT
TH_3810|M.thermoresistible__bu --------------------------------------------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 ------------ESFGSSMGSHGAAGTGFEAQG-----HAQGHASETAHT
MAV_4827|M.avium_104 ------------------GGLGGFGG---------------GHSGGGLGG
Mb0767|M.bovis_AF2122/97 LLGQNGLNGLP-----------------------
Rv0746|M.tuberculosis_H37Rv LLGQNGLNGLP-----------------------
MMAR_1195|M.marinum_M LLGANGNAGMG-----------------------
MUL_3062|M.ulcerans_Agy99 LLGEDGVNGEAAPPMTHIVLLGGDFPAAAS----
Mflv_5091|M.gilvum_PYR-GCK GAGGAG--GAGGSGGSGGSGGSGGSGGAAGDSDD
Mvan_1264|M.vanbaalenii_PYR-1 GTGGAG--GAGGSGGSGGSGGAGGSGGAAGDSD-
MSMEG_0868|M.smegmatis_MC2_155 TAGGSGNGGNGGNGGNGGADGTPGTAGTTGANNP
TH_3810|M.thermoresistible__bu ----------------------------------
MLBr_01183|M.leprae_Br4923 ----------------------------------
MAB_4284c|M.abscessus_ATCC_199 TLPGAEHH--------------------------
MAV_4827|M.avium_104 LGGGHK----------------------------