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SFVIAVPDFIGSAATDLTGIGSTLSAANAAAAIPTTEILAAAEDEISTAIAALFSGHAQAYQAASAQAAA FGSRFVQALTSGAGAYTSAEAASAASIADPLLAAINAPALALTGRPLIGNGANGTPGTGADGAAGGWLLG NGGAGGSGAAGSGQNGGAGGAAGLFGSGGAGGTGGSSSTGNGGAGGAGGAGGLLLGNAGTGGAGGYSNFL TASGGVGGTGGTGGLFGAGGLGGTGGASGMDTGGDGGAGGAGGLLAGLFGSGGGNGGNGGFGSVNGGAGG DGGDGGALAGPGGSGGSGAFGGTLGGDGGAGGAAGLLFGPGGSGGAGGATFSGTGGVGGAGGHAGLFGDG GAGAVGGFSSVDGGAGGAGGDAGWFGNGGIGGAGGAGYFSSGGVGGGGGTGGVLFGNGGAGGNGGTASTG GAGGGGGAGVLIGNGGNAGIGGAGVTVGGTGVGGTSGLLLGLDGFNAPASASPIHALQQQALTAINGPIQ TLTGRPLIGNGTPAAAGSGADGAAGGWLLGDGGAGGSAPLFTAQDAGAGGAAGLWGTGGTGGAGGTSTGG LGGAGGEGGAGGFLAGTGGAGGAGGFSPATGTGAGGVGGAGGAGGLFGGGGGGGVGGGSLAGPGGGGGAG GAGGPLSGLVGAGGGAGGHGGPGDTDGGDGGAGGNGGLLGGAGGAGGTGGYSDDAPSSNGGAGGNAGLLF GNGGHGGSGGASRGFAGTGGAGGNAGLLFGSGGFGGFGGFGSGGGSGGNGGNAGLFGSGGDGGAGGFGVF IDGGSGGSGGSGGPLLGTGGSGGAGGECDLGGFGDGGDGGDGGGAMLIGNGGNGGNGAAGATAGTDGKGG AGGTGGTLLGEDGLNGLT*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. marinum M | MMAR_1850 | - | - | 100% (859) | PE-PGRS family protein |
| M. marinum M | MMAR_2695 | - | 0.0 | 66.18% (887) | PE-PGRS family protein, PE_PGRS9_1 |
| M. marinum M | MMAR_4399 | - | 0.0 | 64.60% (921) | PE-PGRS family protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0767 | PE_PGRS9 | 0.0 | 60.39% (876) | PE-PGRS family protein |
| M. gilvum PYR-GCK | Mflv_5091 | - | 1e-144 | 45.31% (768) | triple helix repeat-containing collagen |
| M. tuberculosis H37Rv | Rv0746 | PE_PGRS9 | 0.0 | 62.55% (817) | PE-PGRS family protein |
| M. leprae Br4923 | MLBr_01183 | - | 1e-12 | 38.54% (96) | hypothetical protein MLBr_01183 |
| M. abscessus ATCC 19977 | MAB_4284c | - | 7e-42 | 34.69% (441) | hypothetical protein MAB_4284c |
| M. avium 104 | MAV_4827 | - | 2e-24 | 41.71% (199) | hypothetical protein MAV_4827 |
| M. smegmatis MC2 155 | MSMEG_0868 | - | 1e-123 | 37.89% (921) | hypothetical protein MSMEG_0868 |
| M. thermoresistible (build 8) | TH_3810 | - | 1e-41 | 40.00% (335) | PUTATIVE - |
| M. ulcerans Agy99 | MUL_3062 | - | 0.0 | 62.25% (898) | PE-PGRS family protein |
| M. vanbaalenii PYR-1 | Mvan_1264 | - | 1e-141 | 43.67% (790) | triple helix repeat-containing collagen |
CLUSTAL 2.0.9 multiple sequence alignment
Mb0767|M.bovis_AF2122/97 --------------------------------------------------
Rv0746|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_1850|M.marinum_M --------------------------------------------------
MUL_3062|M.ulcerans_Agy99 --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_1264|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_0868|M.smegmatis_MC2_155 MHERLRERAGGVRKTLSDFAEGAGLKPSDTDDTRSPLRKPKFPAALAPES
TH_3810|M.thermoresistible__bu --------------------------------------------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 --------------------------------------------------
MAV_4827|M.avium_104 --------------------------------------------------
Mb0767|M.bovis_AF2122/97 ------------------MSFVLAMPEVLGSAATDLAALGS---------
Rv0746|M.tuberculosis_H37Rv ------------------MSFVLAMPEVLGSAATDLAALGS---------
MMAR_1850|M.marinum_M ------------------MSFVIAVPDFIGSAATDLTGIGS---------
MUL_3062|M.ulcerans_Agy99 ------------------MAFVLAVPDMVAEAAADLAGVGS---------
Mflv_5091|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_1264|M.vanbaalenii_PYR-1 -------------------MMFLAPPGGPGPISAAIQLTSTGSEATEP--
MSMEG_0868|M.smegmatis_MC2_155 PLPDLKPRWERPTTAPDSETPSITQPQGRDTAADPAEQQATSTNTTDQPT
TH_3810|M.thermoresistible__bu --------------------------------------------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 -----------MSIIDFILNLFRDPVEAASYVADPEAALAN---------
MAV_4827|M.avium_104 ------------------MNIVLGVSMAPSSIQMVVLEGEYADG------
Mb0767|M.bovis_AF2122/97 -----------------------------------VLGAADAAAAATTTG
Rv0746|M.tuberculosis_H37Rv -----------------------------------VLGAADAAAAATTTG
MMAR_1850|M.marinum_M -----------------------------------TLSAANAAAAIPTTE
MUL_3062|M.ulcerans_Agy99 -----------------------------------VIDAANTAAAGSTTG
Mflv_5091|M.gilvum_PYR-GCK --------------------------------------MVTFGGGATPTP
Mvan_1264|M.vanbaalenii_PYR-1 ------------------------------------WYVVSFGGSGAPTP
MSMEG_0868|M.smegmatis_MC2_155 SDSLGAQPTAQVARQVQAPATDPAPAAPSLRPISGLLSVVTLGTTLIPNA
TH_3810|M.thermoresistible__bu --------------------------------------------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 --------------------------------------AGLSAVSAAQVG
MAV_4827|M.avium_104 ----------------------------------ATVEEDAIDVTGADDA
Mb0767|M.bovis_AF2122/97 IVAAVQDEVSAAIAALFSAHGRAYQVASAQAAAVHAQFVEALSAGAGAYA
Rv0746|M.tuberculosis_H37Rv IVAAAQDEVSAAIAALFSAHGRAYQVASAQAAAVHAQFVEALSAGAGAYA
MMAR_1850|M.marinum_M ILAAAEDEISTAIAALFSGHAQAYQAASAQAAAFGSRFVQALTSGAGAYT
MUL_3062|M.ulcerans_Agy99 IVAAAEDEVSAAIAALFSGHGQAYQQISTRVAEFHAQFERVFAAGVQAYS
Mflv_5091|M.gilvum_PYR-GCK ----------------------------------------TSLGAAAVDL
Mvan_1264|M.vanbaalenii_PYR-1 ----------------------------------------NNLAASLVDL
MSMEG_0868|M.smegmatis_MC2_155 PTEPADMPGVWAVMAWARRQPMYSDPAMRTTVNPQAQLPVPTVASAVLDP
TH_3810|M.thermoresistible__bu --------------------------------------------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 AVMPVVAESVASNYGYQSQWVNTGNPIHDLSGNLQNYYAAQPDGPSILSP
MAV_4827|M.avium_104 ATASAPDRVISAILGTREGAADAGLQLSSIGVTWTDQLEAAALRDALAAR
Mb0767|M.bovis_AF2122/97 S------------------------AEAAGAAVLANPAQSVQQDLLAAVN
Rv0746|M.tuberculosis_H37Rv S------------------------AEAAGAAVLANPAQSVQQDLLAAVN
MMAR_1850|M.marinum_M S------------------------AEAASAASIADP-------LLAAIN
MUL_3062|M.ulcerans_Agy99 G------------------------AEAANASFLQDP----LQTALNATN
Mflv_5091|M.gilvum_PYR-GCK S------------------------GTSCG----------LICNGQDGTG
Mvan_1264|M.vanbaalenii_PYR-1 S------------------------GTSCG----------LICNGQDGTG
MSMEG_0868|M.smegmatis_MC2_155 TQIVNWLIYQPLHAAGQQFWVVSPIGSTLGGVINTISGQYLIGNGINGTA
TH_3810|M.thermoresistible__bu --------------------------------------------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 S-------------------------------------------LLSPRD
MAV_4827|M.avium_104 R--------------------------------------------IDNVM
Mb0767|M.bovis_AF2122/97 AQSVALTGRPLIGNGANGAPG-----TGANGAPGGWLLGNGGAGGSA-AA
Rv0746|M.tuberculosis_H37Rv AQSVALTGRPLIGNGANGAPG-----TGANGAPGGWLLGNGGAGGSA-AA
MMAR_1850|M.marinum_M APALALTGRPLIGNGANGTPG-----TGADGAAGGWLLGNGGAGGSG-AA
MUL_3062|M.ulcerans_Agy99 KPVQDLTGRPLVGNGANGVPG-----TGANGAAGGWLLGNGGAGGSG-AA
Mflv_5091|M.gilvum_PYR-GCK QN-----GGILFGNGGSGWNSDVVGMDGGNGGNGGLFGGNGGNGGNGLGG
Mvan_1264|M.vanbaalenii_PYR-1 QN-----GGILFGNGGSGWNSEIAGVSGGNGGNAGLFGGNGGNGGNGLGS
MSMEG_0868|M.smegmatis_MC2_155 DNPNGGTGGLLFGDGGHGYDGSAAGLAGGNGGNAGLFG-NGGNGGVGWAG
TH_3810|M.thermoresistible__bu ------------------------------------------------VD
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 NDFLSHNDTDFASHNPIASGNQVMSPSGNVDSFNRGPLLDLSFGDLQFGN
MAV_4827|M.avium_104 LVSAFLAAAALAQNVG----------GAMGYERTAVLLVEPDTATLAVVE
Mb0767|M.bovis_AF2122/97 GSGLPGGAGGAAGLFGTGGAGGAGGSS---TVGDGGAGGAGGSGGWLLGT
Rv0746|M.tuberculosis_H37Rv GSGLPGGAGGAAGLFGTGGAGGAGGSS---TVGDGEAGGAGGSGGWLLGT
MMAR_1850|M.marinum_M GSGQNGGAGGAAGLFGSGGAGGTGGSS---STGNGGAGGAGGAGGLLLGN
MUL_3062|M.ulcerans_Agy99 G--QAGGDGGAAGLIGAGGAGGAGGNSPLRNTANGGNGGTGGAGGLLFGP
Mflv_5091|M.gilvum_PYR-GCK GNGGNGGNAGAFALFGNGGNGGNGGVGVVGATGAVG---APGVAGATGAT
Mvan_1264|M.vanbaalenii_PYR-1 GDGGNGGDAGLFSLFGRGGNGGNGGVGIAGATGAVG---APGVAGATGAT
MSMEG_0868|M.smegmatis_MC2_155 LDGGNGGSGG--LLMGIGGAGGAGGVGADGTSAHVDGG-TGGTGGTGGGT
TH_3810|M.thermoresistible__bu GDGGSGGRTGLFSKLSRGGDGGDGGLG--------------GNGGHGGGT
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 RDTTAIGDGAVAVGGSNSGPIASGQGSTAVNGDVRDSNIINADHGSNVGV
MAV_4827|M.avium_104 TSDGSIPDVYKQQIRAESYGDAAGQLSAMVAGLEKLESLPGGLLLVGSGV
Mb0767|M.bovis_AF2122/97 GGVGGVGGLG---AGAGGAGGVGGAGGLLGAGGHGGAG------------
Rv0746|M.tuberculosis_H37Rv GGVGGVGGLG---AGAGGAGGVGGAGGLLGAGGHGGAG------------
MMAR_1850|M.marinum_M AGTGGAGGYSNFLTASGGVGGTGGTGGLFGAGGLGGTG------------
MUL_3062|M.ulcerans_Agy99 GGVGGAGGAS---FLTGGTGGDGGAGGLFGAGGLGGVG------------
Mflv_5091|M.gilvum_PYR-GCK GVTSGVVGGNGEDAVGYGATGAAGAAGAAGAAGAAG--------------
Mvan_1264|M.vanbaalenii_PYR-1 GVTSNVTGGNGADAVGYGATGAAGAAGAAGAAGKAG--------------
MSMEG_0868|M.smegmatis_MC2_155 GGTGGIGGTGGGLFGLLGHSGSTGAAGAAGNGGDGGNGGFGYVLIAGPNV
TH_3810|M.thermoresistible__bu GIIS--------------------LLSLAGNGGNGG--------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 DQSQTRVGGDYTNVSGHGSADIDKSVTVVDDHSQRNTTN-----------
MAV_4827|M.avium_104 DVAPLKQVLQTTTFLDVSVAEEPETALARGAALAAANAP----------L
Mb0767|M.bovis_AF2122/97 GLG-AVTGGVGGAGGAGGLLAGLLAGPGGAGGTGGRGFLND---------
Rv0746|M.tuberculosis_H37Rv GLG-AVTGGVGGTGGAGGLLAGLLAGPGGAGGTGGRGFLNN---------
MMAR_1850|M.marinum_M GASGMDTGGDGGAGGAGGLLAGLFGSGGGNGGNGGFGSVNGGAGGDGGDG
MUL_3062|M.ulcerans_Agy99 GSG--NVGGNGGAGGAGGLLAGLVGAGGGDGGSGGLGAAGGD-GGNGGRA
Mflv_5091|M.gilvum_PYR-GCK AVGSAGAAGEAGETGTWG--NAGLPGKAGDAGGAG---------------
Mvan_1264|M.vanbaalenii_PYR-1 AVGSAGTAGSAGAPGVWG--NAGLPGAAGAAGGAG---------------
MSMEG_0868|M.smegmatis_MC2_155 TVGSETRGGTGGAGGTGGQSTAAGPGKGGGGGGGGGGAILIGANGGTVDG
TH_3810|M.thermoresistible__bu -NGYRTTDNNALDGGHGG--------------------------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 -INDSFNTDRSTNIGSGNTTNTEIGSHNQANIGTS---------------
MAV_4827|M.avium_104 FASSTAALAYAQDPGTGAVDQYSLPDYLYVPVDPE---------------
Mb0767|M.bovis_AF2122/97 ---------------------GGVGGAG----------------GNAGLL
Rv0746|M.tuberculosis_H37Rv ---------------------GGVGGAG----------------GNAGLL
MMAR_1850|M.marinum_M GALAGPGGSGGSGA--FGGTLGGDGGAG----------------GAAGLL
MUL_3062|M.ulcerans_Agy99 GLFGGAGGAGGMGA--TGGHSGGDGGAG----------------GDAGLL
Mflv_5091|M.gilvum_PYR-GCK -AVGAAGAAG------TVGTAGATGGTG---------------TGANGGA
Mvan_1264|M.vanbaalenii_PYR-1 -AIGTAGVAG------AAGTAGATGGTG---------------VGGNGGA
MSMEG_0868|M.smegmatis_MC2_155 HAIGGNGGNGGNGSTTAAGGNGGTGGTGRVIAEGTGSTAEGTATGGDGGH
TH_3810|M.thermoresistible__bu -------------------------------------------NGGNVGF
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 ------------------TSAGGSAAVG----------------GNAGLA
MAV_4827|M.avium_104 -------------------------------------------PGDDELA
Mb0767|M.bovis_AF2122/97 FGAGGTGGSGGAGLG------------GDGGAGGAGGNAGVLFGNAGSGG
Rv0746|M.tuberculosis_H37Rv FGAGGTGGSGGAGLG------------GDGGAGGAGGNTGVLFGNAGSGG
MMAR_1850|M.marinum_M FGPGGSGGAGGATFS------------GTGGVGGAGGHAG-LFGDGGAGA
MUL_3062|M.ulcerans_Agy99 FGTGGAGGAGGHAFD------------GDGGAGGAGGNAGLMFSSGGSGG
Mflv_5091|M.gilvum_PYR-GCK GGVGGVGGTGAAG--------------AAGGAGGLGETGTTGGAGGVGGQ
Mvan_1264|M.vanbaalenii_PYR-1 GQAGGIGGTGAAG--------------AAGQAGTAGETGVTGGVGGIGGQ
MSMEG_0868|M.smegmatis_MC2_155 STGTGIGGNGGIGSVYAYGNNGAVSGTATGGRGGDGIDGGTGGAGGMGEI
TH_3810|M.thermoresistible__bu FSLFNLGG--------------------AGGWGGSGVDG-----------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 GNAGLAGNAGLAGNAG-----------LAGNAGLAGNAGLAGNAGLAGNA
MAV_4827|M.avium_104 YSAVGEEDAESPTVVIEK----------LFLPEDSEPRRRPVLLVGSGLA
Mb0767|M.bovis_AF2122/97 TGGFGDTDGGAGGAGGDAGWLGSGGVGGAGG-------------------
Rv0746|M.tuberculosis_H37Rv TGGFGDTDGGAGGAGGDAGWLGSGGVGGAGG-------------------
MMAR_1850|M.marinum_M VGGFSSVDGGAGGAGGDAGWFGNGGIGGAGG-------------------
MUL_3062|M.ulcerans_Agy99 VGGAGSIDGGAGGAGGDAGWLGGGGAGGAGG-------------------
Mflv_5091|M.gilvum_PYR-GCK --GTAGGTGGVGGIGGAGSTGAVGGVGGKG----IQGGQG----------
Mvan_1264|M.vanbaalenii_PYR-1 --GTEGGTGGVGGVGGVGATGGAGGVGGKG----IQGGQG----------
MSMEG_0868|M.smegmatis_MC2_155 YSGADGEATGISAGGDGGSATGADSLGGRGGTSWVQAGYGPTTGGKASGT
TH_3810|M.thermoresistible__bu ----------VDVVGGNP--------------------------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 GLAGNAGLAGNAGLAGNAGLAGNAGLAGNAG-------------------
MAV_4827|M.avium_104 VVGISAVLALEIALAIGIRTTGTVALQPTPN-------------------
Mb0767|M.bovis_AF2122/97 -----FGETGDGGVGGAGGKAGLLIG---------------------NGG
Rv0746|M.tuberculosis_H37Rv -----FGETGDGGVGGAGGKAGLLIG---------------------NGG
MMAR_1850|M.marinum_M -----AGYFSSGGVGGGGGTGGVLFG---------------------NGG
MUL_3062|M.ulcerans_Agy99 -----FGTISDGGAGGRGGGGGQLLG---------------------NGG
Mflv_5091|M.gilvum_PYR-GCK ---LQGGKGGDGGAGGKGGDADSMGS------------------AGATGG
Mvan_1264|M.vanbaalenii_PYR-1 ---LQGGQGGDGGTGGTGGDATSMGE------------------AGATGG
MSMEG_0868|M.smegmatis_MC2_155 AKAGHGGKASDGGKGGNGGDALVMAAGATGVATGNTAIGGNGGAASANGA
TH_3810|M.thermoresistible__bu ----------DGGTPG------------------------------AHGE
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 ----LAGNAGLAGNAGLAGNAGLAGN----------------------AG
MAV_4827|M.avium_104 -----QHLIVPTEQAPAPPPVQASAP---------------------QPK
Mb0767|M.bovis_AF2122/97 AGGAG---------------------------------------------
Rv0746|M.tuberculosis_H37Rv AGGAGGQGAVTGGTGGAGGDG-----------------------------
MMAR_1850|M.marinum_M AGGNGG-TASTGGAGGGGGAG-----------------------------
MUL_3062|M.ulcerans_Agy99 AGGAGGQGGNDGGAGGLGGNG-----------------------------
Mflv_5091|M.gilvum_PYR-GCK KGGNGGNGGRGGLFG---------------KGGNAGNGAD----------
Mvan_1264|M.vanbaalenii_PYR-1 KGGNGGNGGRGSLFG---------------RGGNAGNGGN----------
MSMEG_0868|M.smegmatis_MC2_155 VGGNGGFTNIAAIHGSITDSSATSGHGGAAQGGNGGNGGNGWVQAYDPNG
TH_3810|M.thermoresistible__bu SHTPGVYTDRQ---------------------------------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 LAGNAGLAGNAGLAGN----------------------------------
MAV_4827|M.avium_104 ISVPEPVAAPKPLSPP----------------------------------
Mb0767|M.bovis_AF2122/97 ----------VLIGNGGNAGIGGTGPTAGDTGAGGISGLLLGADG-----
Rv0746|M.tuberculosis_H37Rv ----------VLIGNGGNAGIGGTGPTAGDTGAGGISGLLLGADG-----
MMAR_1850|M.marinum_M ----------VLIGNGGNAGIGGAGVTVGGTGVGGTSGLLLGLDG-----
MUL_3062|M.ulcerans_Agy99 ----------VLIGNGGNGGVGGVGETPGGDGGGGISGLLLGADG-----
Mflv_5091|M.gilvum_PYR-GCK ------------GGTGGAGGAGGTGG-TGGAGGTGG--------------
Mvan_1264|M.vanbaalenii_PYR-1 ------------GGTGGNGGNGGTGG-TGGNGGTGG--------------
MSMEG_0868|M.smegmatis_MC2_155 PAGTTIDKGKAAGGNGGDGGFNGTGGATGGRGGDGAGASVWKANGQHSTG
TH_3810|M.thermoresistible__bu ----------------GEDGEDGTGTGIGGRGGNGG--------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 ------------AGLAGNAGLAGNAAVAGNAAVAGN--------------
MAV_4827|M.avium_104 -----------VAAPLPAAPPPAAPPLPEAPPIPAAP-------------
Mb0767|M.bovis_AF2122/97 FNAPASASPLHTLKQQALAAINAPTQTLTGRPLIGNGTPGAVGSGATGAP
Rv0746|M.tuberculosis_H37Rv FNTPASASPLHTLKQQALAAINAPTQTLTGRPLIGNGTPGAVGSGATGAP
MMAR_1850|M.marinum_M FNAPASASPIHALQQQALTAINGPIQTLTGRPLIGNGTPAAAGSGADGAA
MUL_3062|M.ulcerans_Agy99 FNAPAGSSPVHALQQQALAAINAPVQELTGRPLIGNGLPGSAGSGAAGAP
Mflv_5091|M.gilvum_PYR-GCK ---TGGTGGIGGAGSTGGTGGTGGTGGTGGTGGTG-GTGGTGGTGGTGGK
Mvan_1264|M.vanbaalenii_PYR-1 ---TGGTGGIGGAGSTGGTGGTGGTGGTGGTGGTG-GTGGTGGTGGTGGK
MSMEG_0868|M.smegmatis_MC2_155 QTDTGGNGGRGGDGGTFVNAGANGNGGAGGAGGVSEGEGGTGGHGGDGGR
TH_3810|M.thermoresistible__bu --SSSGTHPMAEDG--------EHVKALDGRPGLD---GGNGSHGGNGGH
MLBr_01183|M.leprae_Br4923 ------MPLFLNAEPQALTAAANTLEGLSAATVASNAAAAQLTTEIAP--
MAB_4284c|M.abscessus_ATCC_199 -AAVAGNAAVGGVLNTGVSGAIGGSSHVGGAINESLGGSGSVGGSTAVGG
MAV_4827|M.avium_104 ---PVVPVPVVVPPVPVPVPVRIPVPDPVSPPQLLAPPRLSVPQPVQPPV
.
Mb0767|M.bovis_AF2122/97 GG--WLLGDGGAGGS--GAAGSGAPGGAGGAAG---------LWGTGGAG
Rv0746|M.tuberculosis_H37Rv GG--WLLGDGGAGGS--GAAGSGAPGGAGGAAG---------LWGTGGAG
MMAR_1850|M.marinum_M GG--WLLGDGGAGGS--APLFTAQDAGAGGAAG---------LWGTGGTG
MUL_3062|M.ulcerans_Agy99 GG--WLLGDGGAGGS--AAATPGAAGGAGGAAG---------LVGAGGAG
Mflv_5091|M.gilvum_PYR-GCK GGTGGTGGAGGTG----GDGGTGGTGGTGGTG---------GTGGTGGTG
Mvan_1264|M.vanbaalenii_PYR-1 GGTGGTGGDGGTG----GTGGTGGTGGTGGTG---------GTGGTGGTG
MSMEG_0868|M.smegmatis_MC2_155 GGDGALGGNGGTGGVGLGNGGKGGNGGNGGNGGTYVDPSHTGAGGNGGNG
TH_3810|M.thermoresistible__bu GGRGGFLGIGGSG-------GWGGHGGNGGD-----------TDADGGNG
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 GAHTGVGGGVSTGVGVGSHVGGGISESLGGSGS------------VGGST
MAV_4827|M.avium_104 RVPQPPSPPQVGGTVPQSPPQHQTPPGEGTPPK-----------------
Mb0767|M.bovis_AF2122/97 ---------------------GAGGWLLGDGGAGGIGGAS----------
Rv0746|M.tuberculosis_H37Rv GAGGSSAGGGG-----AGGAGGAGGWLLGDGGAGGIGGAS----------
MMAR_1850|M.marinum_M GAGGTSTGGLGG----AGGEGGAGGFLAGTGGAGGAGGFSP---------
MUL_3062|M.ulcerans_Agy99 GAG-----------------ANTGISNPGFGGAGGAGGAG----------
Mflv_5091|M.gilvum_PYR-GCK GAG-----------DGTGGTGGTGG----TGGQGGQGGQGG---------
Mvan_1264|M.vanbaalenii_PYR-1 GAG-----------DGLGGTGGTGG----TGGFGGQGGQGG---------
MSMEG_0868|M.smegmatis_MC2_155 GAGRIRVNNGTATGTATGGNGGNGGNGDADGHRGGKGGDGGEALIRATVI
TH_3810|M.thermoresistible__bu GDG---------------GNGGSAG-------------------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 AVG-----------------------------------------------
MAV_4827|M.avium_104 --------------------------------------------------
Mb0767|M.bovis_AF2122/97 ------TVLGGTGGGGGVGGLWGAGG------------------------
Rv0746|M.tuberculosis_H37Rv ------TVLGGTGGGGGVGGLWGAGG------------------------
MMAR_1850|M.marinum_M ---ATGTGAGGVGGAGGAGGLFGGGG------------------------
MUL_3062|M.ulcerans_Agy99 -----AGAGGGVGEAGGAGGLLGAGG------------------------
Mflv_5091|M.gilvum_PYR-GCK --------TGGTGGQGG-LGGGGGTG-----------------------G
Mvan_1264|M.vanbaalenii_PYR-1 --------TGGTGGQGG-LGGVGGTG-----------------------G
MSMEG_0868|M.smegmatis_MC2_155 GSNASGTATGGDGGNGGTLGATNGTGGAATIVAYNVVQANPQASGTATDG
TH_3810|M.thermoresistible__bu --------RGGTGGLRGVFGINGGNG------------------------
MLBr_01183|M.leprae_Br4923 --------PAADDVSILLAHFFSGHG------------------------
MAB_4284c|M.abscessus_ATCC_199 --------GGAHTGVGGGVSTGVGVG-----------------------S
MAV_4827|M.avium_104 --------PDGPGNYGGGHVPTPGAG------------------------
. . *
Mb0767|M.bovis_AF2122/97 AGGAGGTG---LVGGDGGAGGAG-------------GTGGLLAGLIGAGG
Rv0746|M.tuberculosis_H37Rv AGGAGGTG---LVGGDGGAGGAG-------------GTGGLLAGLIGAGG
MMAR_1850|M.marinum_M GGGVGGGS---LAG-PGGGGGAG-------------GAGGPLSGLVGAGG
MUL_3062|M.ulcerans_Agy99 TGGGGGVAPSLVDGGTGGAGGAG-------------GAGGLFGGIFGAGG
Mflv_5091|M.gilvum_PYR-GCK QGGTGGTGGQGGTGGTGGTGGTG--------GTGGAGGDGGLGGLGGFGG
Mvan_1264|M.vanbaalenii_PYR-1 TGGTGGTGGQGGTGGTGGTGGTG--------GTGGAGGDGGLGGLGGFGG
MSMEG_0868|M.smegmatis_MC2_155 HGGSGINGGHGGNGGQGTIEANGPSAVASGIGAGGNGGDGIDGGLGGNGG
TH_3810|M.thermoresistible__bu RAGLGGRGXXXXGGGVGAAVRSG---------------NGVFSGGGGTPS
MLBr_01183|M.leprae_Br4923 -------RQYQAHASQGATNHQD-------------LIQSLLTSSSAYAG
MAB_4284c|M.abscessus_ATCC_199 HVGGGISESLGGSGSVGGSTAVG---------------GGAHTGVGGGVN
MAV_4827|M.avium_104 -GSGGSGGGHVPTPGAGGSGGSG-------------GGHVPTPGTGGPGG
* . . . .
Mb0767|M.bovis_AF2122/97 GHGGTGGLN--TNGDGGVGGAGGNAGMLAGPGGAGGAGGDG-------EN
Rv0746|M.tuberculosis_H37Rv GHGGTGGLS--TNGDGGVGGAGGNAGMLAGPGGAGGAGGDG-------EN
MMAR_1850|M.marinum_M GAGGHGGP---GDTDGGDGGAGGNGGLLGGAGGAGGTGGYS-------DD
MUL_3062|M.ulcerans_Agy99 GDGGAGGFTGGIDGAGGVGGAGGNTGLLGGPGGSGGSGGDGI------AK
Mflv_5091|M.gilvum_PYR-GCK SGGTGGQGGLGGPGGSTGGAGGAGG--QAGTAGKGGLFG----GSGSAGK
Mvan_1264|M.vanbaalenii_PYR-1 VGGTGGQGGQGGPGGSTGGAGGAGG--QAGVAGKGGLFG----GSGSAGT
MSMEG_0868|M.smegmatis_MC2_155 DGVVNTTANAANPGSATGTATGGDGGKATGTASQGGNGGPSWVQSGYGST
TH_3810|M.thermoresistible__bu AGFGVPTTIQFPAGSCTSRAVSREG------------------------I
MLBr_01183|M.leprae_Br4923 TETANHDSL-----------------------------------------
MAB_4284c|M.abscessus_ATCC_199 TGVGVGSHVGGGISESLGGSGSVGGSTAVGGGAHTSAIN---------DA
MAV_4827|M.avium_104 TGGSGGGHVPTPGAGTPGGSGGGHLPFPGAGSTPGGSGG---------GH
Mb0767|M.bovis_AF2122/97 LDTGGDGGAGGS---AGLLFGSGGAGGAG-----GFG-FLGGDGGAGGNA
Rv0746|M.tuberculosis_H37Rv LDTGGDGGAGGS---AGLLFGSGGAGGAG-----GFG-FLGGDGGAGGNA
MMAR_1850|M.marinum_M APSS-NGGAGGN---AGLLFGNGGHGGSG-----GASRGFAGTGGAGGNA
MUL_3062|M.ulcerans_Agy99 LGFNVDGGAGGAGVNGGFLFGSGGTGGFGGVGGVGTSTGIGGAGGRGGNA
Mflv_5091|M.gilvum_PYR-GCK AGATGAAGASGGKGAQGATGAQGATG------AQGATG-ATGAAGKAGAT
Mvan_1264|M.vanbaalenii_PYR-1 AGVTGASGASGGKGAQGATGAQGATG------AQGATG-ATGASGAQGSA
MSMEG_0868|M.smegmatis_MC2_155 LGGNATGTATAGKGGEASNGGVAGNGGNALVMAAGTTGVATGNTATGGDG
TH_3810|M.thermoresistible__bu MPSSRAASARAG---------------------------AACASSTSRSR
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 LGGSGSVGGSTAVG--------------------GGAHTSAINESMNSSI
MAV_4827|M.avium_104 LPTPGAGTPGGGLGGFG-----------------GGHAPAPGGGLGGGGG
Mb0767|M.bovis_AF2122/97 GLLLSSGGAGGFG-----------------------GFGTAGGVGGAGGN
Rv0746|M.tuberculosis_H37Rv GLLLSSGGAGGFG-----------------------GFGTAGGVGGAGGN
MMAR_1850|M.marinum_M GLLFGSGGFGGFG-----------------------GFGSGGGSGGNGGN
MUL_3062|M.ulcerans_Agy99 GLLFSDAGVGGFG-----------------------GFG------GTGGN
Mflv_5091|M.gilvum_PYR-GCK GAAGAAGAAGSAG-----------TTGAQGSAGTNGA-NGANGSQGAAGK
Mvan_1264|M.vanbaalenii_PYR-1 GSAGSAGVAGSAG-----------TTGAQGSAGTNGA-NGANGSQGAAGK
MSMEG_0868|M.smegmatis_MC2_155 GAATTAGATGGAGGFSNIAAIHGAITDSTAISGHGGAGNGGNGGKGADGW
TH_3810|M.thermoresistible__bu RSFCCSRA------------------------------------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 NASHSSSMNESFG-------------------------------------
MAV_4827|M.avium_104 HAPAPGGGLGGFG-------------------------------------
Mb0767|M.bovis_AF2122/97 AGWLGFGGAGGIGGIGGNANGGAGGNGGTGGQLWGSGGAGGEG-------
Rv0746|M.tuberculosis_H37Rv AGWLGFGGAG----------------------------------------
MMAR_1850|M.marinum_M AGLFGSGGDGGAGGFGVFIDGGSGGSGGSGGPLLGTGGSGGAGG------
MUL_3062|M.ulcerans_Agy99 AGWLGSGGSGGAGG-GSNGDGGAGGTGGSGGQIVGDGGAGGAGGQ-----
Mflv_5091|M.gilvum_PYR-GCK AGATGTTGATG--------AAGEDGDAGSGGSG-INGGAGGAGG------
Mvan_1264|M.vanbaalenii_PYR-1 AGATGTTGATG--------AAGDAGDPGSEAVD-INGGAGGAGG------
MSMEG_0868|M.smegmatis_MC2_155 VQAYDPAGPVGSKIANSSAVAGNGGDGGVNGTGGASGGDGGNGGNTSVWK
TH_3810|M.thermoresistible__bu --------------------------------------------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 --------------------------------------------------
MAV_4827|M.avium_104 --------------------------------------------------
Mb0767|M.bovis_AF2122/97 ------GAALSVGDTGGAGGVGGS--------AGLIGTGGNGGNGGTGAN
Rv0746|M.tuberculosis_H37Rv -------------------GVGGS--------AGLIGTGGNGGNGGTGAN
MMAR_1850|M.marinum_M ------ECDLGGFGDGGDGGDGGG--------AMLIGNGGNGGNGAAGAT
MUL_3062|M.ulcerans_Agy99 ------GDLLAAGGSGGDGGQGGD--------AVLIGTGGNGGNGASGVL
Mflv_5091|M.gilvum_PYR-GCK -----AGGEGGEGGDGGKGGAGAE--------GGAGGGGGAGGSGAGGAG
Mvan_1264|M.vanbaalenii_PYR-1 -----AGGEGGEGGAGGAGGDGSE--------GGAGGSGGAGGSGTGGAG
MSMEG_0868|M.smegmatis_MC2_155 SGGQTADGEHNTGGNGGNGGDGSEPGPGGNGAGGAGGNGGTGGTTAGGSG
TH_3810|M.thermoresistible__bu --------------------------------------------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 --------------------------------------SSMGSHGAAGTG
MAV_4827|M.avium_104 --------------------------------------GGHSGGGLGGLG
Mb0767|M.bovis_AF2122/97 AGSPGTGGAG---GLLLGQNGLNGLP-------------------
Rv0746|M.tuberculosis_H37Rv AGSPGTGGAG---GLLLGQNGLNGLP-------------------
MMAR_1850|M.marinum_M AGTDGKGGAGGTGGTLLGEDGLNGLT-------------------
MUL_3062|M.ulcerans_Agy99 AGIGGDGGSR---GLLLGEDGVNGEAAPPMTHIVLLGGDFPAAAS
Mflv_5091|M.gilvum_PYR-GCK --GAGGSGGSGGSGGSGGSGGAAGDSDD-----------------
Mvan_1264|M.vanbaalenii_PYR-1 --GAGGSGGSGGSGGAGGSGGAAGDSD------------------
MSMEG_0868|M.smegmatis_MC2_155 NGGNGGNGGNGGADGTPGTAGTTGANNP-----------------
TH_3810|M.thermoresistible__bu ---------------------------------------------
MLBr_01183|M.leprae_Br4923 ---------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 FEAQGHAQGHASETAHTTLPGAEHH--------------------
MAV_4827|M.avium_104 GGHK-----------------------------------------