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TEHLDVVIVGAGISGVSAAWHLQDRCPTKSYAILEKRAAMGGTWELFRYPGIRSDSDMHTLGFRFRPWTE RQAIADGKPILEYVKGTAAMYGIDKHIRLNQKVISADWSNAQNRWTLQIESNGAMSAVTCSFLFLCSGYY NYDQGYTPNFAGAQDFAGSIIHPQHWPEDLDYDGKNVVVIGSGASAVTLVPALANSGAKHVTMLQRSPTY IVSQPERDSIAERLNRWLPENMAYAMVRWKNVLRQAAVYGACRKWPRRMRKNFMGLAQRQLPEGYDVRKH FGPHYNPWDQRLCLVPNGDLFRAIRHGQVDVVTDTIDRFTPTGIRLNSGQQLPADIIVTATGLNLQLFGG AAVTVDGESVDLTKAMAYKGMMLSGLPNMAYTVGYTNASWTLKADLVSEFVCRLLNYMDANDYESVVVER PGSDVQECPFMEFTPGYVLRVIDELPKQGSRKPWRLNQDYLRDIHLIRRGKIDDEGLRFAKKPVAVPV*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. ulcerans Agy99 | MUL_5026 | ethA | - | 100% (489) | monooxygenase EthA |
| M. ulcerans Agy99 | MUL_4352 | - | e-144 | 51.23% (486) | monooxygenase-like flavoprotein |
| M. ulcerans Agy99 | MUL_4873 | - | 8e-36 | 26.61% (466) | monooxygenase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3884c | ethA | 0.0 | 84.66% (489) | monooxygenase ETHA |
| M. gilvum PYR-GCK | Mflv_0962 | - | 0.0 | 64.62% (489) | monooxygenase, flavin-binding family protein |
| M. tuberculosis H37Rv | Rv3854c | ethA | 0.0 | 84.66% (489) | monooxygenase ETHA |
| M. leprae Br4923 | MLBr_00065 | - | 0.0 | 78.07% (488) | putative monooxygenase |
| M. abscessus ATCC 19977 | MAB_0103 | - | 1e-180 | 60.29% (486) | monooxygenase EthA |
| M. marinum M | MMAR_5404 | ethA | 0.0 | 98.98% (489) | monooxygenase EthA |
| M. avium 104 | MAV_0175 | - | 0.0 | 65.96% (473) | monooxygenase, flavin-binding family protein |
| M. smegmatis MC2 155 | MSMEG_6440 | - | 0.0 | 65.30% (487) | monooxygenase, flavin-binding family protein |
| M. thermoresistible (build 8) | TH_1149 | - | 0.0 | 66.81% (455) | MONOOXYGENASE ETHA |
| M. vanbaalenii PYR-1 | Mvan_5683 | - | 0.0 | 64.48% (487) | hypothetical protein Mvan_5683 |
CLUSTAL 2.0.9 multiple sequence alignment
MUL_5026|M.ulcerans_Agy99 -----MTEHLDVVIVGAGISGVSAAWHLQDRCPTKSYAILEKRAAMGGTW
MMAR_5404|M.marinum_M -----MTEHLDVVIVGAGISGVSAAWHLQDRCPTKSYAILEKRAAMGGTW
Mb3884c|M.bovis_AF2122/97 -----MTEHLDVVIVGAGISGVSAAWHLQDRCPTKSYAILEKRESMGGTW
Rv3854c|M.tuberculosis_H37Rv -----MTEHLDVVIVGAGISGVSAAWHLQDRCPTKSYAILEKRESMGGTW
MLBr_00065|M.leprae_Br4923 MVVMAETEYLDVVIVGAGISGVSAAWHLQDRCPNKSYVILEKRAGMGGTW
Mflv_0962|M.gilvum_PYR-GCK -----MSDHFDVVIVGAGISGISTAWHLQQRCPDKSYVILERRENIGGTW
MSMEG_6440|M.smegmatis_MC2_155 -----MTEHFDVVIVGAGISGISTAWHLQDRCPTKSYVILERRANIGGTW
MAV_0175|M.avium_104 ---------------------MSAAWHLQNRCPTKSYAILERRADLGGTW
TH_1149|M.thermoresistible__bu ---VVMTEHLDVLIVGAGISGISAAWHLQDRCPSKSYAILERRDNLGGTW
Mvan_5683|M.vanbaalenii_PYR-1 -----MTEFVDVVIVGAGISGISAAWHLQDRCPGKSYVILERRDNLGGTW
MAB_0103|M.abscessus_ATCC_1997 -----MSEHFDVLIVGAGISGISAAWHIQDRCPTKTYAVLEARDDMGGTW
:*:***:*:*** *:*.:** * :****
MUL_5026|M.ulcerans_Agy99 ELFRYPGIRSDSDMHTLGFRFRPWTERQAIADGKPILEYVKGTAAMYGID
MMAR_5404|M.marinum_M DLFRYPGIRSDSDMHTLGFRFRPWTERQAIADGKPILEYVKGTAAMYGID
Mb3884c|M.bovis_AF2122/97 DLFRYPGIRSDSDMYTLGFRFRPWTGRQAIADGKPILEYVKSTAAMYGID
Rv3854c|M.tuberculosis_H37Rv DLFRYPGIRSDSDMYTLGFRFRPWTGRQAIADGKPILEYVKSTAAMYGID
MLBr_00065|M.leprae_Br4923 DLFRYPGIRSDSDMYTLGFRFRPWTKCQAIADGKPILEYIKSTAVMHGID
Mflv_0962|M.gilvum_PYR-GCK DLFKYPGIRSDSDMFTLGFRFKPWPSARSIADGPSIWNYINEAAQENGID
MSMEG_6440|M.smegmatis_MC2_155 DLFKYPGIRSDSDMFTLGFRFKPWTSAKSIADGPSIWNYINEAAQENGID
MAV_0175|M.avium_104 DLFKYPGIRSDSDMFTLGFRFKPWRSAKSIADGASIKAYIKEAAVENRIE
TH_1149|M.thermoresistible__bu DLFKYPGIRSDSDMFTLGFRFKPWTDPKAIADGPDILAYLKETAEEFGID
Mvan_5683|M.vanbaalenii_PYR-1 DLFKYPGIRSDSDMFTLGFRFKPWTSDKAIADGPDIMAYLNETVAEYGID
MAB_0103|M.abscessus_ATCC_1997 NLFKYPGIRSDSDMYTLGFRFSPWNDSRTLADGPSILDYVHKTAANAGID
:**:**********.****** ** :::*** * *:: :. *:
MUL_5026|M.ulcerans_Agy99 KHIRLNQKVISADWSNAQNRWTLQIESNGAMSAVTCSFLFLCSGYYNYDQ
MMAR_5404|M.marinum_M KHIRLNQKVISADWSNAQNRWTLQIESNGATSAVTCSFLFLCSGYYNYDQ
Mb3884c|M.bovis_AF2122/97 RHIRFHHKVISADWSTAENRWTVHIQSHGTLSALTCEFLFLCSGYYNYDE
Rv3854c|M.tuberculosis_H37Rv RHIRFHHKVISADWSTAENRWTVHIQSHGTLSALTCEFLFLCSGYYNYDE
MLBr_00065|M.leprae_Br4923 KYIRLNHKVTGADWSSIENRWTVQVENNGTPRMISCSFLFLCSGYYNYEQ
Mflv_0962|M.gilvum_PYR-GCK KHIRVKHQVLAANWSDAENRWELTVDHDGEQKQITCSFLSVCSGYYNYDQ
MSMEG_6440|M.smegmatis_MC2_155 KHIRTNHRVLGADWSDAENRWTITVEADGEQKQITASFLSVCSGYYNYDQ
MAV_0175|M.avium_104 PHIRYRHRVVAADWSDADNRWTVTVEHDGQRSEITCSFLFACTGYYNYDE
TH_1149|M.thermoresistible__bu EHIRYRHRVVSANWSDPDNKWILQVERDGEQVEMTCSFLFACSGYYNYDE
Mvan_5683|M.vanbaalenii_PYR-1 KHIRYGQNVKSADWSDADNRWTVRVDRAGEEVEISARYLMACSGYYNYDE
MAB_0103|M.abscessus_ATCC_1997 GHVRYRQKVVGAAWNTETQQWTVEVDHDGKTIEYTCSFLFCCSGYYDYDQ
::* :.* .* *. ::* : :: * :. :* *:***:*::
MUL_5026|M.ulcerans_Agy99 GYTPNFAGAQDFAGSIIHPQHWPEDLDYDGKNVVVIGSGASAVTLVPALA
MMAR_5404|M.marinum_M GYTPNFAGAQDFAGSIIHPQHWPEDLDYDGKNVVVIGSGATAVTLVPALA
Mb3884c|M.bovis_AF2122/97 GYSPRFAGSEDFVGPIIHPQHWPEDLDYDAKNIVVIGSGATAVTLVPALA
Rv3854c|M.tuberculosis_H37Rv GYSPRFAGSEDFVGPIIHPQHWPEDLDYDAKNIVVIGSGATAVTLVPALA
MLBr_00065|M.leprae_Br4923 GYAPTFLGSEDFTGPIIHPQHWPEDLDYAAKNIVVIGSGATAVTLVPALA
Mflv_0962|M.gilvum_PYR-GCK GYSPEFPGADDFAGQIIHPQHWPEDLDYTGKRIVVIGSGATAVTLIPSLV
MSMEG_6440|M.smegmatis_MC2_155 GYSPEFPGADDFAGQIIHPQHWPEDLDYAGKKIVVIGSGATAVTLIPSLV
MAV_0175|M.avium_104 GYSPTFPGAEDFGGTIVHPQHWPEDLDYAGKRIVVIGSGATAITLIPALV
TH_1149|M.thermoresistible__bu GYSPEFPGADDFEGTIVHPQHWPEDLDYAGKRIVVIGSGATAVTLIPALA
Mvan_5683|M.vanbaalenii_PYR-1 GYSPDFPGSEDFEGTLIHPQHWPEDLDYAGKRIVVIGSGATAVTLIPALA
MAB_0103|M.abscessus_ATCC_1997 GYSPEFPGVADFKGTVVHPQHWPEDLDYKGKKVVVIGSGATAVTLVPAMA
**:* * * ** * ::*********** .*.:*******:*:**:*::.
MUL_5026|M.ulcerans_Agy99 NSGAKHVTMLQRSPTYIVSQPERDSIAERLNRWLPENMAYAMVRWKNVLR
MMAR_5404|M.marinum_M NSGAKHVTMLQRSPTYIVSQPERDSIAERLNRWLPENMAYAMVRWKNVLR
Mb3884c|M.bovis_AF2122/97 DSGAKHVTMLQRSPTYIVSQPDRDGIAEKLNRWLPETMAYTAVRWKNVLR
Rv3854c|M.tuberculosis_H37Rv DSGAKHVTMLQRSPTYIVSQPDRDGIAEKLNRWLPETMAYTAVRWKNVLR
MLBr_00065|M.leprae_Br4923 NSGAKHVTMLQRSPTYIVSQPAKDKIAARLNRWLPDKYAYTAVRWKNILR
Mflv_0962|M.gilvum_PYR-GCK AGGAGHVTMLQRSPTYIGSLPLVDPIAEKANKYLPGSLAHFVNRWKAISF
MSMEG_6440|M.smegmatis_MC2_155 NGGAAHVTMLQRSPTYIGSLPLVDPVAEKTNKYLPKNLAHFVNRWKAIAF
MAV_0175|M.avium_104 NSGAGHVTMLQRSPTYIGSLPGVDPFAERANRLLPDRLAHMANRWKAIAF
TH_1149|M.thermoresistible__bu ETGAGHVTMLQRSPTYIGSLPLVDPIAVKVNKYLPPKMASVVNRWKAIIF
Mvan_5683|M.vanbaalenii_PYR-1 NSGAGHVTMLQRSPTFIAALPDVDPFTVATNKRLPAKVAYVLNRWKSILQ
MAB_0103|M.abscessus_ATCC_1997 P-DTGHITMLQRSPTYIMSLPNENPIINGLRKILPPKVAYPIARWINIGQ
.: *:********:* : * : . .: ** * ** :
MUL_5026|M.ulcerans_Agy99 QAAVYGACRKWPRRMRKNFMGLAQRQLPEGYDVRKHFGPHYNPWDQRLCL
MMAR_5404|M.marinum_M QAAVYGACRKWPRRMRKNFMGLAQRQLPEGYDVRKHFGPHYNPWDQRLCL
Mb3884c|M.bovis_AF2122/97 QAAVYSACQKWPRRMRKMFLSLIQRQLPEGYDVRKHFGPHYNPWDQRLCL
Rv3854c|M.tuberculosis_H37Rv QAAVYSACQKWPRRMRKMFLSLIQRQLPEGYDVRKHFGPHYNPWDQRLCL
MLBr_00065|M.leprae_Br4923 QSALYGACQKWPQRMRNILLGHVARRLPKGYDVQKHFGPHYNPWEQRLCL
Mflv_0962|M.gilvum_PYR-GCK STLQYQLSQRFPKYMRKTLMTMAQRRLPEGYDVEKHFGPRYNPWDERLCL
MSMEG_6440|M.smegmatis_MC2_155 STAQYQLARKFPNYMRKTLMTMAQRRLPEGFDVQKHFGPRYNPWDERLCL
MAV_0175|M.avium_104 STFQYQLSRKAPAYMRKTLMTMAKRRLPEGYDVEKHFGPRYNVWDERLCL
TH_1149|M.thermoresistible__bu STFQYQLSRKFPNYMRRTLMRMAERRLPPGYDVEKHFGPRYNPWDERLCL
Mvan_5683|M.vanbaalenii_PYR-1 QSVQYQVARKFPDFFRKQLLTMAKHRLPEGYDVNKHFNPRYNPWDERVCL
MAB_0103|M.abscessus_ATCC_1997 LIFSYQASRKFPRAARRIIMQQAKLQLPKGFDYKTHFGPKYNPWDERLCV
* .:: * *. :: :** *:* ..**.*:** *::*:*:
MUL_5026|M.ulcerans_Agy99 VPNGDLFRAIRHGQVDVVTDTIDRFTPTGIRLNSGQQLPADIIVTATGLN
MMAR_5404|M.marinum_M VPNGDLFRAIRHGQVDVVTDTIDRFTPTGIRLNSGQQLPADIIVTATGLN
Mb3884c|M.bovis_AF2122/97 VPNGDLFRAIRHGKVEVVTDTIERFTATGIRLNSGRELPADIIITATGLN
Rv3854c|M.tuberculosis_H37Rv VPNGDLFRAIRHGKVEVVTDTIERFTATGIRLNSGRELPADIIITATGLN
MLBr_00065|M.leprae_Br4923 VPDGDLFRAIRKGTVDMVTDAIDRFTSTGIRLKSGNELRADIIVTATGLN
Mflv_0962|M.gilvum_PYR-GCK APNGDLFKTIRAGKADVVTDTIDRFTETGIRLNSGEELAADIIITATGLN
MSMEG_6440|M.smegmatis_MC2_155 APNGDLFKTIRAGKADVVTDTIAKFTETGIKLTSGEELTADIIITATGLN
MAV_0175|M.avium_104 APDGDFFRTIRHGKADVVTDTIDRFTTTGIRLNSGEELPADIIVTATGLN
TH_1149|M.thermoresistible__bu APNGDLFRAIRHGKADVVTDTIDTFTKTGIRLTSGTELEADIIITATGLN
Mvan_5683|M.vanbaalenii_PYR-1 APNGDLFKTIRAGKADVVTDTIERFTKTGIQLASGRHLDADIIVTATGLN
MAB_0103|M.abscessus_ATCC_1997 VPNGDLYKAIRKGKADIVTDHIETFDETGIKLKSGKHLDADIIITATGLN
.*:**::::** * .::*** * * ***:* ** .* ****:******
MUL_5026|M.ulcerans_Agy99 LQLFGGAAVTVDGESVDLTKAMAYKGMMLSGLPNMAYTVGYTNASWTLKA
MMAR_5404|M.marinum_M LQLFGGAAVTVDGESVDLTKAMAYKGMMLSGLPNMAYTVGYTNASWTLKA
Mb3884c|M.bovis_AF2122/97 LQLFGGATATIDGQQVDITTTMAYKGMMLSGIPNMAYTVGYTNASWTLKA
Rv3854c|M.tuberculosis_H37Rv LQLFGGATATIDGQQVDITTTMAYKGMMLSGIPNMAYTVGYTNASWTLKA
MLBr_00065|M.leprae_Br4923 LQLFGGAVATVDGQPVDLAQTMSYKGMMLSGLPNMIYTVGYTNASWTLKA
Mflv_0962|M.gilvum_PYR-GCK MQLFGGATATRNGEPIDLTKTMTYKGLMLSGVPNMAITFGYTNASWTLKA
MSMEG_6440|M.smegmatis_MC2_155 MQLFGGASLTRNGQEVDLTETMTYKGLMLSGVPNMAITFGYTNASWTLKA
MAV_0175|M.avium_104 MQLLGGVTPTRNGDPVDLTSLMTYKGLMFSGMPNFAITFGYTNASWTLKA
TH_1149|M.thermoresistible__bu LQLFGGAEIKRNGQPVELTETMAYKGMMLSGMPNMAFTIGYTNASWTLKA
Mvan_5683|M.vanbaalenii_PYR-1 LQLFGGATISRNGEAIELNDTMAYKGMLLTDMPNLAFTIGYTNASWTLKA
MAB_0103|M.abscessus_ATCC_1997 LKFFSGVIPTVDGVPVDLPAQTVYKGAMLTGIPNMAFTIGYTNASWTLKA
::::.*. . :* ::: *** :::.:**: *.***********
MUL_5026|M.ulcerans_Agy99 DLVSEFVCRLLNYMDANDYESVVVERPGSDVQECPFMEFTPGYVLRVIDE
MMAR_5404|M.marinum_M DLVSEFVCRLLNYMDANDYDSVVVERPGSDVQECPFMEFTPGYVLRVIDE
Mb3884c|M.bovis_AF2122/97 DLVSEFVCRLLNYMDDNGFDTVVVERPGSDVEERPFMEFTPGYVLRSLDE
Rv3854c|M.tuberculosis_H37Rv DLVSEFVCRLLNYMDDNGFDTVVVERPGSDVEERPFMEFTPGYVLRSLDE
MLBr_00065|M.leprae_Br4923 DLVSEFFCRLLNYMNANDFDTVAVEYPGSDVEERPFMDFTPGYVLRSLDA
Mflv_0962|M.gilvum_PYR-GCK DLVSEFICRLLNYMDDNGFDRVEAQHPGDSVEEKPFMDFSPGYFRRAMDT
MSMEG_6440|M.smegmatis_MC2_155 DLVSEFICRVLNYMDDNGFDRVEPQHPGDAVDALPFMDFNPGYFRRAMDS
MAV_0175|M.avium_104 DLVSEFVCRLLNYMDAKGFDFVEPQHPGEDVDALPFMDFTPGYFRRSMHL
TH_1149|M.thermoresistible__bu DLVSEFVCRVLNHMDEHGYDVVEPQHPGDSVEERPLLDFTPGYVLRALDR
Mvan_5683|M.vanbaalenii_PYR-1 DLVSEFFCRIINYMDANSYDRVEPRHPGSSVDERPLMDFTPGYVLRALDY
MAB_0103|M.abscessus_ATCC_1997 DLVSEYVSRLLNYMDENGYVTAVPELADETLEKQPFMDFTPGYVLRALDE
*****:..*::*:*: :.: . . ... :: *:::*.***. * :.
MUL_5026|M.ulcerans_Agy99 LPKQGSRKPWR--LNQDYLRDIHLIRRGKIDDEGLRFAKKPVAVPV----
MMAR_5404|M.marinum_M LPKQGSRKPWR--LNQNYLRDIHLIRRGKIDDEGLRFAKKPVAVPV----
Mb3884c|M.bovis_AF2122/97 LPKQGSRTPWR--LNQNYLRDIRLIRRGKIDDEGLRFAKRPAPVGV----
Rv3854c|M.tuberculosis_H37Rv LPKQGSRTPWR--LNQNYLRDIRLIRRGKIDDEGLRFAKRPAPVGV----
MLBr_00065|M.leprae_Br4923 LPKQGSRTPWR--LNQNYLRDIRLIRRGKVADEGLLFAKKTTPVTV----
Mflv_0962|M.gilvum_PYR-GCK LPKSGSEAPWR--LKQNYFIDLRTIRYGKVDEESLRFTKHGAPVALSS--
MSMEG_6440|M.smegmatis_MC2_155 LPKSGSRAPWR--LKQNYFFDLRMIRYDKVDEESLHFTKHRAAVSASSS-
MAV_0175|M.avium_104 LPKSGSRAPWR--LKQNYFFDMRTIRRGRVDDEGLKFAKKRAPVAV----
TH_1149|M.thermoresistible__bu LPPPXXXRMWWTRCRRSRFAAGPPAWRSTTRRRSSRPRPGRWGSTGCG--
Mvan_5683|M.vanbaalenii_PYR-1 LPKAGSRAPWR--LKQNYLMDLQLIRRGKVDDEALAFSRHPAQVTASA--
MAB_0103|M.abscessus_ATCC_1997 LPKQGNKHPWR--LKQNYAYDIGMMRRSRVT-EGMRFGRKKTAAAPASES
** * .:. . ..
MUL_5026|M.ulcerans_Agy99 -----
MMAR_5404|M.marinum_M -----
Mb3884c|M.bovis_AF2122/97 -----
Rv3854c|M.tuberculosis_H37Rv -----
MLBr_00065|M.leprae_Br4923 -----
Mflv_0962|M.gilvum_PYR-GCK -----
MSMEG_6440|M.smegmatis_MC2_155 -----
MAV_0175|M.avium_104 -----
TH_1149|M.thermoresistible__bu -----
Mvan_5683|M.vanbaalenii_PYR-1 -----
MAB_0103|M.abscessus_ATCC_1997 VAVNS