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M. thermoresistible (build 8) TH_1149 ()

annotation: MONOOXYGENASE ETHA
coordinates: 2223944 - 2225431
length: 496

aa seq not available

Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. thermoresistible (build 8)TH_1149-100% (496)MONOOXYGENASE ETHA
M. thermoresistible (build 8)TH_2757-e-12849.13% (458) PUTATIVE FAD dependent oxidoreductase
M. thermoresistible (build 8)TH_2696-7e-3726.95% (449) PUTATIVE putative FAD dependent oxidoreductase

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb3884cethA0.067.69% (455) monooxygenase ETHA
M. gilvum PYR-GCKMflv_0962-0.075.82% (455) monooxygenase, flavin-binding family protein
M. tuberculosis H37RvRv3854cethA0.067.69% (455) monooxygenase ETHA
M. leprae Br4923MLBr_00065-0.065.64% (454) putative monooxygenase
M. abscessus ATCC 19977MAB_0103-1e-18061.57% (484) monooxygenase EthA
M. marinum MMMAR_5404ethA0.067.47% (455) monooxygenase EthA
M. avium 104MAV_0175-0.074.72% (439) monooxygenase, flavin-binding family protein
M. smegmatis MC2 155MSMEG_6440-0.076.26% (455) monooxygenase, flavin-binding family protein
M. ulcerans Agy99MUL_5026ethA0.066.81% (455) monooxygenase EthA
M. vanbaalenii PYR-1Mvan_5683-0.074.73% (455) hypothetical protein Mvan_5683

CLUSTAL 2.0.9 multiple sequence alignment


Mb3884c|M.bovis_AF2122/97           -----MTEHLDVVIVGAGISGVSAAWHLQDRCPTKSYAILEKRESMGGTW
Rv3854c|M.tuberculosis_H37Rv        -----MTEHLDVVIVGAGISGVSAAWHLQDRCPTKSYAILEKRESMGGTW
MMAR_5404|M.marinum_M               -----MTEHLDVVIVGAGISGVSAAWHLQDRCPTKSYAILEKRAAMGGTW
MUL_5026|M.ulcerans_Agy99           -----MTEHLDVVIVGAGISGVSAAWHLQDRCPTKSYAILEKRAAMGGTW
MLBr_00065|M.leprae_Br4923          MVVMAETEYLDVVIVGAGISGVSAAWHLQDRCPNKSYVILEKRAGMGGTW
Mflv_0962|M.gilvum_PYR-GCK          -----MSDHFDVVIVGAGISGISTAWHLQQRCPDKSYVILERRENIGGTW
MSMEG_6440|M.smegmatis_MC2_155      -----MTEHFDVVIVGAGISGISTAWHLQDRCPTKSYVILERRANIGGTW
MAV_0175|M.avium_104                ---------------------MSAAWHLQNRCPTKSYAILERRADLGGTW
TH_1149|M.thermoresistible__bu      ---VVMTEHLDVLIVGAGISGISAAWHLQDRCPSKSYAILERRDNLGGTW
Mvan_5683|M.vanbaalenii_PYR-1       -----MTEFVDVVIVGAGISGISAAWHLQDRCPGKSYVILERRDNLGGTW
MAB_0103|M.abscessus_ATCC_1997      -----MSEHFDVLIVGAGISGISAAWHIQDRCPTKTYAVLEARDDMGGTW
                                                         :*:***:*:*** *:*.:** *  :****

Mb3884c|M.bovis_AF2122/97           DLFRYPGIRSDSDMYTLGFRFRPWTGRQAIADGKPILEYVKSTAAMYGID
Rv3854c|M.tuberculosis_H37Rv        DLFRYPGIRSDSDMYTLGFRFRPWTGRQAIADGKPILEYVKSTAAMYGID
MMAR_5404|M.marinum_M               DLFRYPGIRSDSDMHTLGFRFRPWTERQAIADGKPILEYVKGTAAMYGID
MUL_5026|M.ulcerans_Agy99           ELFRYPGIRSDSDMHTLGFRFRPWTERQAIADGKPILEYVKGTAAMYGID
MLBr_00065|M.leprae_Br4923          DLFRYPGIRSDSDMYTLGFRFRPWTKCQAIADGKPILEYIKSTAVMHGID
Mflv_0962|M.gilvum_PYR-GCK          DLFKYPGIRSDSDMFTLGFRFKPWPSARSIADGPSIWNYINEAAQENGID
MSMEG_6440|M.smegmatis_MC2_155      DLFKYPGIRSDSDMFTLGFRFKPWTSAKSIADGPSIWNYINEAAQENGID
MAV_0175|M.avium_104                DLFKYPGIRSDSDMFTLGFRFKPWRSAKSIADGASIKAYIKEAAVENRIE
TH_1149|M.thermoresistible__bu      DLFKYPGIRSDSDMFTLGFRFKPWTDPKAIADGPDILAYLKETAEEFGID
Mvan_5683|M.vanbaalenii_PYR-1       DLFKYPGIRSDSDMFTLGFRFKPWTSDKAIADGPDIMAYLNETVAEYGID
MAB_0103|M.abscessus_ATCC_1997      NLFKYPGIRSDSDMYTLGFRFSPWNDSRTLADGPSILDYVHKTAANAGID
                                    :**:**********.****** **   :::***  *  *:: :.    *:

Mb3884c|M.bovis_AF2122/97           RHIRFHHKVISADWSTAENRWTVHIQSHGTLSALTCEFLFLCSGYYNYDE
Rv3854c|M.tuberculosis_H37Rv        RHIRFHHKVISADWSTAENRWTVHIQSHGTLSALTCEFLFLCSGYYNYDE
MMAR_5404|M.marinum_M               KHIRLNQKVISADWSNAQNRWTLQIESNGATSAVTCSFLFLCSGYYNYDQ
MUL_5026|M.ulcerans_Agy99           KHIRLNQKVISADWSNAQNRWTLQIESNGAMSAVTCSFLFLCSGYYNYDQ
MLBr_00065|M.leprae_Br4923          KYIRLNHKVTGADWSSIENRWTVQVENNGTPRMISCSFLFLCSGYYNYEQ
Mflv_0962|M.gilvum_PYR-GCK          KHIRVKHQVLAANWSDAENRWELTVDHDGEQKQITCSFLSVCSGYYNYDQ
MSMEG_6440|M.smegmatis_MC2_155      KHIRTNHRVLGADWSDAENRWTITVEADGEQKQITASFLSVCSGYYNYDQ
MAV_0175|M.avium_104                PHIRYRHRVVAADWSDADNRWTVTVEHDGQRSEITCSFLFACTGYYNYDE
TH_1149|M.thermoresistible__bu      EHIRYRHRVVSANWSDPDNKWILQVERDGEQVEMTCSFLFACSGYYNYDE
Mvan_5683|M.vanbaalenii_PYR-1       KHIRYGQNVKSADWSDADNRWTVRVDRAGEEVEISARYLMACSGYYNYDE
MAB_0103|M.abscessus_ATCC_1997      GHVRYRQKVVGAAWNTETQQWTVEVDHDGKTIEYTCSFLFCCSGYYDYDQ
                                     ::*  :.* .* *.   ::* : ::  *     :. :*  *:***:*::

Mb3884c|M.bovis_AF2122/97           GYSPRFAGSEDFVGPIIHPQHWPEDLDYDAKNIVVIGSGATAVTLVPALA
Rv3854c|M.tuberculosis_H37Rv        GYSPRFAGSEDFVGPIIHPQHWPEDLDYDAKNIVVIGSGATAVTLVPALA
MMAR_5404|M.marinum_M               GYTPNFAGAQDFAGSIIHPQHWPEDLDYDGKNVVVIGSGATAVTLVPALA
MUL_5026|M.ulcerans_Agy99           GYTPNFAGAQDFAGSIIHPQHWPEDLDYDGKNVVVIGSGASAVTLVPALA
MLBr_00065|M.leprae_Br4923          GYAPTFLGSEDFTGPIIHPQHWPEDLDYAAKNIVVIGSGATAVTLVPALA
Mflv_0962|M.gilvum_PYR-GCK          GYSPEFPGADDFAGQIIHPQHWPEDLDYTGKRIVVIGSGATAVTLIPSLV
MSMEG_6440|M.smegmatis_MC2_155      GYSPEFPGADDFAGQIIHPQHWPEDLDYAGKKIVVIGSGATAVTLIPSLV
MAV_0175|M.avium_104                GYSPTFPGAEDFGGTIVHPQHWPEDLDYAGKRIVVIGSGATAITLIPALV
TH_1149|M.thermoresistible__bu      GYSPEFPGADDFEGTIVHPQHWPEDLDYAGKRIVVIGSGATAVTLIPALA
Mvan_5683|M.vanbaalenii_PYR-1       GYSPDFPGSEDFEGTLIHPQHWPEDLDYAGKRIVVIGSGATAVTLIPALA
MAB_0103|M.abscessus_ATCC_1997      GYSPEFPGVADFKGTVVHPQHWPEDLDYKGKKVVVIGSGATAVTLVPAMA
                                    **:* * *  ** * ::*********** .*.:*******:*:**:*::.

Mb3884c|M.bovis_AF2122/97           DSGAKHVTMLQRSPTYIVSQPDRDGIAEKLNRWLPETMAYTAVRWKNVLR
Rv3854c|M.tuberculosis_H37Rv        DSGAKHVTMLQRSPTYIVSQPDRDGIAEKLNRWLPETMAYTAVRWKNVLR
MMAR_5404|M.marinum_M               NSGAKHVTMLQRSPTYIVSQPERDSIAERLNRWLPENMAYAMVRWKNVLR
MUL_5026|M.ulcerans_Agy99           NSGAKHVTMLQRSPTYIVSQPERDSIAERLNRWLPENMAYAMVRWKNVLR
MLBr_00065|M.leprae_Br4923          NSGAKHVTMLQRSPTYIVSQPAKDKIAARLNRWLPDKYAYTAVRWKNILR
Mflv_0962|M.gilvum_PYR-GCK          AGGAGHVTMLQRSPTYIGSLPLVDPIAEKANKYLPGSLAHFVNRWKAISF
MSMEG_6440|M.smegmatis_MC2_155      NGGAAHVTMLQRSPTYIGSLPLVDPVAEKTNKYLPKNLAHFVNRWKAIAF
MAV_0175|M.avium_104                NSGAGHVTMLQRSPTYIGSLPGVDPFAERANRLLPDRLAHMANRWKAIAF
TH_1149|M.thermoresistible__bu      ETGAGHVTMLQRSPTYIGSLPLVDPIAVKVNKYLPPKMASVVNRWKAIIF
Mvan_5683|M.vanbaalenii_PYR-1       NSGAGHVTMLQRSPTFIAALPDVDPFTVATNKRLPAKVAYVLNRWKSILQ
MAB_0103|M.abscessus_ATCC_1997      P-DTGHITMLQRSPTYIMSLPNENPIINGLRKILPPKVAYPIARWINIGQ
                                      .: *:********:* : *  : .    .: **   *    **  :  

Mb3884c|M.bovis_AF2122/97           QAAVYSACQKWPRRMRKMFLSLIQRQLPEGYDVRKHFGPHYNPWDQRLCL
Rv3854c|M.tuberculosis_H37Rv        QAAVYSACQKWPRRMRKMFLSLIQRQLPEGYDVRKHFGPHYNPWDQRLCL
MMAR_5404|M.marinum_M               QAAVYGACRKWPRRMRKNFMGLAQRQLPEGYDVRKHFGPHYNPWDQRLCL
MUL_5026|M.ulcerans_Agy99           QAAVYGACRKWPRRMRKNFMGLAQRQLPEGYDVRKHFGPHYNPWDQRLCL
MLBr_00065|M.leprae_Br4923          QSALYGACQKWPQRMRNILLGHVARRLPKGYDVQKHFGPHYNPWEQRLCL
Mflv_0962|M.gilvum_PYR-GCK          STLQYQLSQRFPKYMRKTLMTMAQRRLPEGYDVEKHFGPRYNPWDERLCL
MSMEG_6440|M.smegmatis_MC2_155      STAQYQLARKFPNYMRKTLMTMAQRRLPEGFDVQKHFGPRYNPWDERLCL
MAV_0175|M.avium_104                STFQYQLSRKAPAYMRKTLMTMAKRRLPEGYDVEKHFGPRYNVWDERLCL
TH_1149|M.thermoresistible__bu      STFQYQLSRKFPNYMRRTLMRMAERRLPPGYDVEKHFGPRYNPWDERLCL
Mvan_5683|M.vanbaalenii_PYR-1       QSVQYQVARKFPDFFRKQLLTMAKHRLPEGYDVNKHFNPRYNPWDERVCL
MAB_0103|M.abscessus_ATCC_1997      LIFSYQASRKFPRAARRIIMQQAKLQLPKGFDYKTHFGPKYNPWDERLCV
                                        *  .:: *   *. ::     :** *:* ..**.*:** *::*:*:

Mb3884c|M.bovis_AF2122/97           VPNGDLFRAIRHGKVEVVTDTIERFTATGIRLNSGRELPADIIITATGLN
Rv3854c|M.tuberculosis_H37Rv        VPNGDLFRAIRHGKVEVVTDTIERFTATGIRLNSGRELPADIIITATGLN
MMAR_5404|M.marinum_M               VPNGDLFRAIRHGQVDVVTDTIDRFTPTGIRLNSGQQLPADIIVTATGLN
MUL_5026|M.ulcerans_Agy99           VPNGDLFRAIRHGQVDVVTDTIDRFTPTGIRLNSGQQLPADIIVTATGLN
MLBr_00065|M.leprae_Br4923          VPDGDLFRAIRKGTVDMVTDAIDRFTSTGIRLKSGNELRADIIVTATGLN
Mflv_0962|M.gilvum_PYR-GCK          APNGDLFKTIRAGKADVVTDTIDRFTETGIRLNSGEELAADIIITATGLN
MSMEG_6440|M.smegmatis_MC2_155      APNGDLFKTIRAGKADVVTDTIAKFTETGIKLTSGEELTADIIITATGLN
MAV_0175|M.avium_104                APDGDFFRTIRHGKADVVTDTIDRFTTTGIRLNSGEELPADIIVTATGLN
TH_1149|M.thermoresistible__bu      APNGDLFRAIRHGKADVVTDTIDTFTKTGIRLTSGTELEADIIITATGLN
Mvan_5683|M.vanbaalenii_PYR-1       APNGDLFKTIRAGKADVVTDTIERFTKTGIQLASGRHLDADIIVTATGLN
MAB_0103|M.abscessus_ATCC_1997      VPNGDLYKAIRKGKADIVTDHIETFDETGIKLKSGKHLDADIIITATGLN
                                    .*:**::::** * .::*** *  *  ***:* ** .* ****:******

Mb3884c|M.bovis_AF2122/97           LQLFGGATATIDGQQVDITTTMAYKGMMLSGIPNMAYTVGYTNASWTLKA
Rv3854c|M.tuberculosis_H37Rv        LQLFGGATATIDGQQVDITTTMAYKGMMLSGIPNMAYTVGYTNASWTLKA
MMAR_5404|M.marinum_M               LQLFGGAAVTVDGESVDLTKAMAYKGMMLSGLPNMAYTVGYTNASWTLKA
MUL_5026|M.ulcerans_Agy99           LQLFGGAAVTVDGESVDLTKAMAYKGMMLSGLPNMAYTVGYTNASWTLKA
MLBr_00065|M.leprae_Br4923          LQLFGGAVATVDGQPVDLAQTMSYKGMMLSGLPNMIYTVGYTNASWTLKA
Mflv_0962|M.gilvum_PYR-GCK          MQLFGGATATRNGEPIDLTKTMTYKGLMLSGVPNMAITFGYTNASWTLKA
MSMEG_6440|M.smegmatis_MC2_155      MQLFGGASLTRNGQEVDLTETMTYKGLMLSGVPNMAITFGYTNASWTLKA
MAV_0175|M.avium_104                MQLLGGVTPTRNGDPVDLTSLMTYKGLMFSGMPNFAITFGYTNASWTLKA
TH_1149|M.thermoresistible__bu      LQLFGGAEIKRNGQPVELTETMAYKGMMLSGMPNMAFTIGYTNASWTLKA
Mvan_5683|M.vanbaalenii_PYR-1       LQLFGGATISRNGEAIELNDTMAYKGMLLTDMPNLAFTIGYTNASWTLKA
MAB_0103|M.abscessus_ATCC_1997      LKFFSGVIPTVDGVPVDLPAQTVYKGAMLTGIPNMAFTIGYTNASWTLKA
                                    ::::.*.  . :*  :::     *** :::.:**:  *.***********

Mb3884c|M.bovis_AF2122/97           DLVSEFVCRLLNYMDDNGFDTVVVERPGSDVEERPFMEFTPGYVLRSLDE
Rv3854c|M.tuberculosis_H37Rv        DLVSEFVCRLLNYMDDNGFDTVVVERPGSDVEERPFMEFTPGYVLRSLDE
MMAR_5404|M.marinum_M               DLVSEFVCRLLNYMDANDYDSVVVERPGSDVQECPFMEFTPGYVLRVIDE
MUL_5026|M.ulcerans_Agy99           DLVSEFVCRLLNYMDANDYESVVVERPGSDVQECPFMEFTPGYVLRVIDE
MLBr_00065|M.leprae_Br4923          DLVSEFFCRLLNYMNANDFDTVAVEYPGSDVEERPFMDFTPGYVLRSLDA
Mflv_0962|M.gilvum_PYR-GCK          DLVSEFICRLLNYMDDNGFDRVEAQHPGDSVEEKPFMDFSPGYFRRAMDT
MSMEG_6440|M.smegmatis_MC2_155      DLVSEFICRVLNYMDDNGFDRVEPQHPGDAVDALPFMDFNPGYFRRAMDS
MAV_0175|M.avium_104                DLVSEFVCRLLNYMDAKGFDFVEPQHPGEDVDALPFMDFTPGYFRRSMHL
TH_1149|M.thermoresistible__bu      DLVSEFVCRVLNHMDEHGYDVVEPQHPGDSVEERPLLDFTPGYVLRALDR
Mvan_5683|M.vanbaalenii_PYR-1       DLVSEFFCRIINYMDANSYDRVEPRHPGSSVDERPLMDFTPGYVLRALDY
MAB_0103|M.abscessus_ATCC_1997      DLVSEYVSRLLNYMDENGYVTAVPELADETLEKQPFMDFTPGYVLRALDE
                                    *****:..*::*:*: :.:  .  . ... ::  *:::*.***. * :. 

Mb3884c|M.bovis_AF2122/97           LPKQGSRTPWR--LNQNYLRDIRLIRRGKIDDEGLRFAKRPAPVGV----
Rv3854c|M.tuberculosis_H37Rv        LPKQGSRTPWR--LNQNYLRDIRLIRRGKIDDEGLRFAKRPAPVGV----
MMAR_5404|M.marinum_M               LPKQGSRKPWR--LNQNYLRDIHLIRRGKIDDEGLRFAKKPVAVPV----
MUL_5026|M.ulcerans_Agy99           LPKQGSRKPWR--LNQDYLRDIHLIRRGKIDDEGLRFAKKPVAVPV----
MLBr_00065|M.leprae_Br4923          LPKQGSRTPWR--LNQNYLRDIRLIRRGKVADEGLLFAKKTTPVTV----
Mflv_0962|M.gilvum_PYR-GCK          LPKSGSEAPWR--LKQNYFIDLRTIRYGKVDEESLRFTKHGAPVALSS--
MSMEG_6440|M.smegmatis_MC2_155      LPKSGSRAPWR--LKQNYFFDLRMIRYDKVDEESLHFTKHRAAVSASSS-
MAV_0175|M.avium_104                LPKSGSRAPWR--LKQNYFFDMRTIRRGRVDDEGLKFAKKRAPVAV----
TH_1149|M.thermoresistible__bu      LPPPXXXRMWWTRCRRSRFAAGPPAWRSTTRRRSSRPRPGRWGSTGCG--
Mvan_5683|M.vanbaalenii_PYR-1       LPKAGSRAPWR--LKQNYLMDLQLIRRGKVDDEALAFSRHPAQVTASA--
MAB_0103|M.abscessus_ATCC_1997      LPKQGNKHPWR--LKQNYAYDIGMMRRSRVT-EGMRFGRKKTAAAPASES
                                    **       *    .:.          .    ..                

Mb3884c|M.bovis_AF2122/97           -----
Rv3854c|M.tuberculosis_H37Rv        -----
MMAR_5404|M.marinum_M               -----
MUL_5026|M.ulcerans_Agy99           -----
MLBr_00065|M.leprae_Br4923          -----
Mflv_0962|M.gilvum_PYR-GCK          -----
MSMEG_6440|M.smegmatis_MC2_155      -----
MAV_0175|M.avium_104                -----
TH_1149|M.thermoresistible__bu      -----
Mvan_5683|M.vanbaalenii_PYR-1       -----
MAB_0103|M.abscessus_ATCC_1997      VAVNS