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TEFVDVVIVGAGISGISAAWHLQDRCPGKSYVILERRDNLGGTWDLFKYPGIRSDSDMFTLGFRFKPWTS DKAIADGPDIMAYLNETVAEYGIDKHIRYGQNVKSADWSDADNRWTVRVDRAGEEVEISARYLMACSGYY NYDEGYSPDFPGSEDFEGTLIHPQHWPEDLDYAGKRIVVIGSGATAVTLIPALANSGAGHVTMLQRSPTF IAALPDVDPFTVATNKRLPAKVAYVLNRWKSILQQSVQYQVARKFPDFFRKQLLTMAKHRLPEGYDVNKH FNPRYNPWDERVCLAPNGDLFKTIRAGKADVVTDTIERFTKTGIQLASGRHLDADIIVTATGLNLQLFGG ATISRNGEAIELNDTMAYKGMLLTDMPNLAFTIGYTNASWTLKADLVSEFFCRIINYMDANSYDRVEPRH PGSSVDERPLMDFTPGYVLRALDYLPKAGSRAPWRLKQNYLMDLQLIRRGKVDDEALAFSRHPAQVTASA *
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. vanbaalenii PYR-1 | Mvan_5683 | - | - | 100% (491) | hypothetical protein Mvan_5683 |
| M. vanbaalenii PYR-1 | Mvan_1867 | - | e-140 | 48.16% (490) | FAD dependent oxidoreductase |
| M. vanbaalenii PYR-1 | Mvan_2671 | - | 8e-37 | 28.28% (442) | cyclohexanone monooxygenase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3884c | ethA | 0.0 | 66.12% (487) | monooxygenase ETHA |
| M. gilvum PYR-GCK | Mflv_1123 | - | 0.0 | 81.35% (488) | FAD dependent oxidoreductase |
| M. tuberculosis H37Rv | Rv3854c | ethA | 0.0 | 66.12% (487) | monooxygenase ETHA |
| M. leprae Br4923 | MLBr_00065 | - | 0.0 | 64.89% (487) | putative monooxygenase |
| M. abscessus ATCC 19977 | MAB_0103 | - | 1e-177 | 59.13% (482) | monooxygenase EthA |
| M. marinum M | MMAR_5404 | ethA | 0.0 | 65.30% (487) | monooxygenase EthA |
| M. avium 104 | MAV_0175 | - | 0.0 | 69.00% (471) | monooxygenase, flavin-binding family protein |
| M. smegmatis MC2 155 | MSMEG_6440 | - | 0.0 | 71.08% (491) | monooxygenase, flavin-binding family protein |
| M. thermoresistible (build 8) | TH_1149 | - | 0.0 | 74.73% (455) | MONOOXYGENASE ETHA |
| M. ulcerans Agy99 | MUL_5026 | ethA | 0.0 | 64.48% (487) | monooxygenase EthA |
CLUSTAL 2.0.9 multiple sequence alignment
Mb3884c|M.bovis_AF2122/97 -----MTEHLDVVIVGAGISGVSAAWHLQDRCPTKSYAILEKRESMGGTW
Rv3854c|M.tuberculosis_H37Rv -----MTEHLDVVIVGAGISGVSAAWHLQDRCPTKSYAILEKRESMGGTW
MMAR_5404|M.marinum_M -----MTEHLDVVIVGAGISGVSAAWHLQDRCPTKSYAILEKRAAMGGTW
MUL_5026|M.ulcerans_Agy99 -----MTEHLDVVIVGAGISGVSAAWHLQDRCPTKSYAILEKRAAMGGTW
MLBr_00065|M.leprae_Br4923 MVVMAETEYLDVVIVGAGISGVSAAWHLQDRCPNKSYVILEKRAGMGGTW
Mvan_5683|M.vanbaalenii_PYR-1 -----MTEFVDVVIVGAGISGISAAWHLQDRCPGKSYVILERRDNLGGTW
Mflv_1123|M.gilvum_PYR-GCK -----MTEEVDVVVVGAGISGISAAWHLQNRCPGKSYVILEGRDDLGGTW
TH_1149|M.thermoresistible__bu ---VVMTEHLDVLIVGAGISGISAAWHLQDRCPSKSYAILERRDNLGGTW
MAV_0175|M.avium_104 ---------------------MSAAWHLQNRCPTKSYAILERRADLGGTW
MSMEG_6440|M.smegmatis_MC2_155 -----MTEHFDVVIVGAGISGISTAWHLQDRCPTKSYVILERRANIGGTW
MAB_0103|M.abscessus_ATCC_1997 -----MSEHFDVLIVGAGISGISAAWHIQDRCPTKTYAVLEARDDMGGTW
:*:***:*:*** *:*.:** * :****
Mb3884c|M.bovis_AF2122/97 DLFRYPGIRSDSDMYTLGFRFRPWTGRQAIADGKPILEYVKSTAAMYGID
Rv3854c|M.tuberculosis_H37Rv DLFRYPGIRSDSDMYTLGFRFRPWTGRQAIADGKPILEYVKSTAAMYGID
MMAR_5404|M.marinum_M DLFRYPGIRSDSDMHTLGFRFRPWTERQAIADGKPILEYVKGTAAMYGID
MUL_5026|M.ulcerans_Agy99 ELFRYPGIRSDSDMHTLGFRFRPWTERQAIADGKPILEYVKGTAAMYGID
MLBr_00065|M.leprae_Br4923 DLFRYPGIRSDSDMYTLGFRFRPWTKCQAIADGKPILEYIKSTAVMHGID
Mvan_5683|M.vanbaalenii_PYR-1 DLFKYPGIRSDSDMFTLGFRFKPWTSDKAIADGPDIMAYLNETVAEYGID
Mflv_1123|M.gilvum_PYR-GCK DLFRYPGIRSDSDMFTLGFRFKPWTSEKAIADAPSIMAYLRETVAEFGID
TH_1149|M.thermoresistible__bu DLFKYPGIRSDSDMFTLGFRFKPWTDPKAIADGPDILAYLKETAEEFGID
MAV_0175|M.avium_104 DLFKYPGIRSDSDMFTLGFRFKPWRSAKSIADGASIKAYIKEAAVENRIE
MSMEG_6440|M.smegmatis_MC2_155 DLFKYPGIRSDSDMFTLGFRFKPWTSAKSIADGPSIWNYINEAAQENGID
MAB_0103|M.abscessus_ATCC_1997 NLFKYPGIRSDSDMYTLGFRFSPWNDSRTLADGPSILDYVHKTAANAGID
:**:**********.****** ** :::**. * *:. :. *:
Mb3884c|M.bovis_AF2122/97 RHIRFHHKVISADWSTAENRWTVHIQSHGTLSALTCEFLFLCSGYYNYDE
Rv3854c|M.tuberculosis_H37Rv RHIRFHHKVISADWSTAENRWTVHIQSHGTLSALTCEFLFLCSGYYNYDE
MMAR_5404|M.marinum_M KHIRLNQKVISADWSNAQNRWTLQIESNGATSAVTCSFLFLCSGYYNYDQ
MUL_5026|M.ulcerans_Agy99 KHIRLNQKVISADWSNAQNRWTLQIESNGAMSAVTCSFLFLCSGYYNYDQ
MLBr_00065|M.leprae_Br4923 KYIRLNHKVTGADWSSIENRWTVQVENNGTPRMISCSFLFLCSGYYNYEQ
Mvan_5683|M.vanbaalenii_PYR-1 KHIRYGQNVKSADWSDADNRWTVRVDRAGEEVEISARYLMACSGYYNYDE
Mflv_1123|M.gilvum_PYR-GCK RHIRYGHRMVAADWSDADNRWTVHVERGGERVEISARYLMACSGYYDYDR
TH_1149|M.thermoresistible__bu EHIRYRHRVVSANWSDPDNKWILQVERDGEQVEMTCSFLFACSGYYNYDE
MAV_0175|M.avium_104 PHIRYRHRVVAADWSDADNRWTVTVEHDGQRSEITCSFLFACTGYYNYDE
MSMEG_6440|M.smegmatis_MC2_155 KHIRTNHRVLGADWSDAENRWTITVEADGEQKQITASFLSVCSGYYNYDQ
MAB_0103|M.abscessus_ATCC_1997 GHVRYRQKVVGAAWNTETQQWTVEVDHDGKTIEYTCSFLFCCSGYYDYDQ
::* :.: .* *. ::* : :: * :. :* *:***:*:.
Mb3884c|M.bovis_AF2122/97 GYSPRFAGSEDFVGPIIHPQHWPEDLDYDAKNIVVIGSGATAVTLVPALA
Rv3854c|M.tuberculosis_H37Rv GYSPRFAGSEDFVGPIIHPQHWPEDLDYDAKNIVVIGSGATAVTLVPALA
MMAR_5404|M.marinum_M GYTPNFAGAQDFAGSIIHPQHWPEDLDYDGKNVVVIGSGATAVTLVPALA
MUL_5026|M.ulcerans_Agy99 GYTPNFAGAQDFAGSIIHPQHWPEDLDYDGKNVVVIGSGASAVTLVPALA
MLBr_00065|M.leprae_Br4923 GYAPTFLGSEDFTGPIIHPQHWPEDLDYAAKNIVVIGSGATAVTLVPALA
Mvan_5683|M.vanbaalenii_PYR-1 GYSPDFPGSEDFEGTLIHPQHWPEDLDYAGKRIVVIGSGATAVTLIPALA
Mflv_1123|M.gilvum_PYR-GCK GYSPEFAGAQDFEGPIIHPQHWPEDLDYTGKRVVVIGSGATAVTLVPALA
TH_1149|M.thermoresistible__bu GYSPEFPGADDFEGTIVHPQHWPEDLDYAGKRIVVIGSGATAVTLIPALA
MAV_0175|M.avium_104 GYSPTFPGAEDFGGTIVHPQHWPEDLDYAGKRIVVIGSGATAITLIPALV
MSMEG_6440|M.smegmatis_MC2_155 GYSPEFPGADDFAGQIIHPQHWPEDLDYAGKKIVVIGSGATAVTLIPSLV
MAB_0103|M.abscessus_ATCC_1997 GYSPEFPGVADFKGTVVHPQHWPEDLDYKGKKVVVIGSGATAVTLVPAMA
**:* * * ** * ::*********** .*.:*******:*:**:*::.
Mb3884c|M.bovis_AF2122/97 DSGAKHVTMLQRSPTYIVSQPDRDGIAEKLNRWLPETMAYTAVRWKNVLR
Rv3854c|M.tuberculosis_H37Rv DSGAKHVTMLQRSPTYIVSQPDRDGIAEKLNRWLPETMAYTAVRWKNVLR
MMAR_5404|M.marinum_M NSGAKHVTMLQRSPTYIVSQPERDSIAERLNRWLPENMAYAMVRWKNVLR
MUL_5026|M.ulcerans_Agy99 NSGAKHVTMLQRSPTYIVSQPERDSIAERLNRWLPENMAYAMVRWKNVLR
MLBr_00065|M.leprae_Br4923 NSGAKHVTMLQRSPTYIVSQPAKDKIAARLNRWLPDKYAYTAVRWKNILR
Mvan_5683|M.vanbaalenii_PYR-1 NSGAGHVTMLQRSPTFIAALPDVDPFTVATNKRLPAKVAYVLNRWKSILQ
Mflv_1123|M.gilvum_PYR-GCK DSGAGHVTMLQRSPTYIGALPDVDPFTVRTNKTLPTGAAYVVNRWKSILF
TH_1149|M.thermoresistible__bu ETGAGHVTMLQRSPTYIGSLPLVDPIAVKVNKYLPPKMASVVNRWKAIIF
MAV_0175|M.avium_104 NSGAGHVTMLQRSPTYIGSLPGVDPFAERANRLLPDRLAHMANRWKAIAF
MSMEG_6440|M.smegmatis_MC2_155 NGGAAHVTMLQRSPTYIGSLPLVDPVAEKTNKYLPKNLAHFVNRWKAIAF
MAB_0103|M.abscessus_ATCC_1997 P-DTGHITMLQRSPTYIMSLPNENPIINGLRKILPPKVAYPIARWINIGQ
.: *:********:* : * : . .: ** * ** :
Mb3884c|M.bovis_AF2122/97 QAAVYSACQKWPRRMRKMFLSLIQRQLPEGYDVRKHFGPHYNPWDQRLCL
Rv3854c|M.tuberculosis_H37Rv QAAVYSACQKWPRRMRKMFLSLIQRQLPEGYDVRKHFGPHYNPWDQRLCL
MMAR_5404|M.marinum_M QAAVYGACRKWPRRMRKNFMGLAQRQLPEGYDVRKHFGPHYNPWDQRLCL
MUL_5026|M.ulcerans_Agy99 QAAVYGACRKWPRRMRKNFMGLAQRQLPEGYDVRKHFGPHYNPWDQRLCL
MLBr_00065|M.leprae_Br4923 QSALYGACQKWPQRMRNILLGHVARRLPKGYDVQKHFGPHYNPWEQRLCL
Mvan_5683|M.vanbaalenii_PYR-1 QSVQYQVARKFPDFFRKQLLTMAKHRLPEGYDVNKHFNPRYNPWDERVCL
Mflv_1123|M.gilvum_PYR-GCK QSVQYQLSRRFPRFMRRTLMTMAQRRLPEGYDIARHFGPSYNPWDQRLCL
TH_1149|M.thermoresistible__bu STFQYQLSRKFPNYMRRTLMRMAERRLPPGYDVEKHFGPRYNPWDERLCL
MAV_0175|M.avium_104 STFQYQLSRKAPAYMRKTLMTMAKRRLPEGYDVEKHFGPRYNVWDERLCL
MSMEG_6440|M.smegmatis_MC2_155 STAQYQLARKFPNYMRKTLMTMAQRRLPEGFDVQKHFGPRYNPWDERLCL
MAB_0103|M.abscessus_ATCC_1997 LIFSYQASRKFPRAARRIIMQQAKLQLPKGFDYKTHFGPKYNPWDERLCV
* .:: * *. :: :** *:* **.* ** *::*:*:
Mb3884c|M.bovis_AF2122/97 VPNGDLFRAIRHGKVEVVTDTIERFTATGIRLNSGRELPADIIITATGLN
Rv3854c|M.tuberculosis_H37Rv VPNGDLFRAIRHGKVEVVTDTIERFTATGIRLNSGRELPADIIITATGLN
MMAR_5404|M.marinum_M VPNGDLFRAIRHGQVDVVTDTIDRFTPTGIRLNSGQQLPADIIVTATGLN
MUL_5026|M.ulcerans_Agy99 VPNGDLFRAIRHGQVDVVTDTIDRFTPTGIRLNSGQQLPADIIVTATGLN
MLBr_00065|M.leprae_Br4923 VPDGDLFRAIRKGTVDMVTDAIDRFTSTGIRLKSGNELRADIIVTATGLN
Mvan_5683|M.vanbaalenii_PYR-1 APNGDLFKTIRAGKADVVTDTIERFTKTGIQLASGRHLDADIIVTATGLN
Mflv_1123|M.gilvum_PYR-GCK APNGDLFETIRTGRADVVTDTIERFDRTGITLSSGQHLDADIIVTATGLN
TH_1149|M.thermoresistible__bu APNGDLFRAIRHGKADVVTDTIDTFTKTGIRLTSGTELEADIIITATGLN
MAV_0175|M.avium_104 APDGDFFRTIRHGKADVVTDTIDRFTTTGIRLNSGEELPADIIVTATGLN
MSMEG_6440|M.smegmatis_MC2_155 APNGDLFKTIRAGKADVVTDTIAKFTETGIKLTSGEELTADIIITATGLN
MAB_0103|M.abscessus_ATCC_1997 VPNGDLYKAIRKGKADIVTDHIETFDETGIKLKSGKHLDADIIITATGLN
.*:**::.:** * .::*** * * *** * ** .* ****:******
Mb3884c|M.bovis_AF2122/97 LQLFGGATATIDGQQVDITTTMAYKGMMLSGIPNMAYTVGYTNASWTLKA
Rv3854c|M.tuberculosis_H37Rv LQLFGGATATIDGQQVDITTTMAYKGMMLSGIPNMAYTVGYTNASWTLKA
MMAR_5404|M.marinum_M LQLFGGAAVTVDGESVDLTKAMAYKGMMLSGLPNMAYTVGYTNASWTLKA
MUL_5026|M.ulcerans_Agy99 LQLFGGAAVTVDGESVDLTKAMAYKGMMLSGLPNMAYTVGYTNASWTLKA
MLBr_00065|M.leprae_Br4923 LQLFGGAVATVDGQPVDLAQTMSYKGMMLSGLPNMIYTVGYTNASWTLKA
Mvan_5683|M.vanbaalenii_PYR-1 LQLFGGATISRNGEAIELNDTMAYKGMLLTDMPNLAFTIGYTNASWTLKA
Mflv_1123|M.gilvum_PYR-GCK LRLFGGAVISRNGEVIELSETMAYKGMLLTGMPNLAFTIGYTNASWTLKA
TH_1149|M.thermoresistible__bu LQLFGGAEIKRNGQPVELTETMAYKGMMLSGMPNMAFTIGYTNASWTLKA
MAV_0175|M.avium_104 MQLLGGVTPTRNGDPVDLTSLMTYKGLMFSGMPNFAITFGYTNASWTLKA
MSMEG_6440|M.smegmatis_MC2_155 MQLFGGASLTRNGQEVDLTETMTYKGLMLSGVPNMAITFGYTNASWTLKA
MAB_0103|M.abscessus_ATCC_1997 LKFFSGVIPTVDGVPVDLPAQTVYKGAMLTGIPNMAFTIGYTNASWTLKA
::::.*. . :* ::: *** :::.:**: *.***********
Mb3884c|M.bovis_AF2122/97 DLVSEFVCRLLNYMDDNGFDTVVVERPGSDVEERPFMEFTPGYVLRSLDE
Rv3854c|M.tuberculosis_H37Rv DLVSEFVCRLLNYMDDNGFDTVVVERPGSDVEERPFMEFTPGYVLRSLDE
MMAR_5404|M.marinum_M DLVSEFVCRLLNYMDANDYDSVVVERPGSDVQECPFMEFTPGYVLRVIDE
MUL_5026|M.ulcerans_Agy99 DLVSEFVCRLLNYMDANDYESVVVERPGSDVQECPFMEFTPGYVLRVIDE
MLBr_00065|M.leprae_Br4923 DLVSEFFCRLLNYMNANDFDTVAVEYPGSDVEERPFMDFTPGYVLRSLDA
Mvan_5683|M.vanbaalenii_PYR-1 DLVSEFFCRIINYMDANSYDRVEPRHPGSSVDERPLMDFTPGYVLRALDY
Mflv_1123|M.gilvum_PYR-GCK DLVSEFFCRIINYMDEHSYTRMEPRHPGGGVDERPLLDFTPGYVLRALDH
TH_1149|M.thermoresistible__bu DLVSEFVCRVLNHMDEHGYDVVEPQHPGDSVEERPLLDFTPGYVLRALDR
MAV_0175|M.avium_104 DLVSEFVCRLLNYMDAKGFDFVEPQHPGEDVDALPFMDFTPGYFRRSMHL
MSMEG_6440|M.smegmatis_MC2_155 DLVSEFICRVLNYMDDNGFDRVEPQHPGDAVDALPFMDFNPGYFRRAMDS
MAB_0103|M.abscessus_ATCC_1997 DLVSEYVSRLLNYMDENGYVTAVPELADETLEKQPFMDFTPGYVLRALDE
*****:..*::*:*: :.: . .. :: *:::*.***. * :.
Mb3884c|M.bovis_AF2122/97 LPKQG-SRTPW-RLNQNYLRDIRLIRRGKIDDEGLRFAKRPAPVGV----
Rv3854c|M.tuberculosis_H37Rv LPKQG-SRTPW-RLNQNYLRDIRLIRRGKIDDEGLRFAKRPAPVGV----
MMAR_5404|M.marinum_M LPKQG-SRKPW-RLNQNYLRDIHLIRRGKIDDEGLRFAKKPVAVPV----
MUL_5026|M.ulcerans_Agy99 LPKQG-SRKPW-RLNQDYLRDIHLIRRGKIDDEGLRFAKKPVAVPV----
MLBr_00065|M.leprae_Br4923 LPKQG-SRTPW-RLNQNYLRDIRLIRRGKVADEGLLFAKKTTPVTV----
Mvan_5683|M.vanbaalenii_PYR-1 LPKAG-SRAPW-RLKQNYLMDLQLIRRGKVDDEALAFSRHPAQVTASA--
Mflv_1123|M.gilvum_PYR-GCK LPKAG-SRAPW-RLKQNYLLDLQLIRRGRVDDEALEFGQSAVTTTIPSSS
TH_1149|M.thermoresistible__bu LPPPXXXRMWWTRCRRSRFAAGPPAWRSTTRRRSSRPRPGRWGSTGCG--
MAV_0175|M.avium_104 LPKSG-SRAPW-RLKQNYFFDMRTIRRGRVDDEGLKFAKKRAPVAV----
MSMEG_6440|M.smegmatis_MC2_155 LPKSG-SRAPW-RLKQNYFFDLRMIRYDKVDEESLHFTKHRAAVSASSS-
MAB_0103|M.abscessus_ATCC_1997 LPKQG-NKHPW-RLKQNYAYDIGMMRRSRVT-EGMRFGRKKTAAAPASES
** : * * .:. . ..
Mb3884c|M.bovis_AF2122/97 -----
Rv3854c|M.tuberculosis_H37Rv -----
MMAR_5404|M.marinum_M -----
MUL_5026|M.ulcerans_Agy99 -----
MLBr_00065|M.leprae_Br4923 -----
Mvan_5683|M.vanbaalenii_PYR-1 -----
Mflv_1123|M.gilvum_PYR-GCK L----
TH_1149|M.thermoresistible__bu -----
MAV_0175|M.avium_104 -----
MSMEG_6440|M.smegmatis_MC2_155 -----
MAB_0103|M.abscessus_ATCC_1997 VAVNS