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TVASRTSADPLGPDSLTWKYFGDLRTGMMGVWIGAIQNMYPELGAGVEEHSILLREPLQRVARSVYPIMG VVYDGDRAAQTGQQIKGYHRTIKGVDAEGRRYHALNPDTFYWAHATFFMLVIKVAEYFCGGLTEAEKHQL FEEHVRWYRMYGMSMRPVPKSWEDFQDYWDRVCRDKLEINQATVDILQMRIPKPRFVLMPTPIWDQLFKP LIAGQRWIAAGLFDPAVREKAGMHWTPGDEVLLRVFGKVVELAFLAVPDEIRLHPRALAAYRRAAGRTRH DAPLVQAPGFMAPPRDRQGLPMHYFPPRSHRFTRSALDPAKALMERAGALVHSTLSLAGVRPARGPSRAA *
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. tuberculosis H37Rv | Rv1645c | - | - | 100% (351) | hypothetical protein Rv1645c |
| M. tuberculosis H37Rv | Rv0826 | - | 6e-98 | 57.53% (299) | hypothetical protein Rv0826 |
| M. tuberculosis H37Rv | Rv0276 | - | 1e-05 | 24.14% (174) | hypothetical protein Rv0276 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1672c | - | 0.0 | 100.00% (351) | hypothetical protein Mb1672c |
| M. gilvum PYR-GCK | Mflv_3536 | - | 1e-164 | 77.26% (343) | hypothetical protein Mflv_3536 |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_0757 | - | 7e-95 | 55.85% (299) | hypothetical protein MAB_0757 |
| M. marinum M | MMAR_2452 | - | 1e-180 | 84.81% (349) | hypothetical protein MMAR_2452 |
| M. avium 104 | MAV_3124 | - | 1e-177 | 82.82% (355) | hypothetical protein MAV_3124 |
| M. smegmatis MC2 155 | MSMEG_3781 | - | 1e-166 | 78.96% (347) | hypothetical protein MSMEG_3781 |
| M. thermoresistible (build 8) | TH_1589 | - | 1e-164 | 78.17% (339) | CONSERVED HYPOTHETICAL PROTEIN |
| M. ulcerans Agy99 | MUL_1631 | - | 1e-178 | 83.67% (349) | hypothetical protein MUL_1631 |
| M. vanbaalenii PYR-1 | Mvan_3322 | - | 1e-165 | 76.38% (343) | hypothetical protein Mvan_3322 |
CLUSTAL 2.0.9 multiple sequence alignment
Rv1645c|M.tuberculosis_H37Rv ------------MTVAS---------------------------------
Mb1672c|M.bovis_AF2122/97 ------------MTVAS---------------------------------
MMAR_2452|M.marinum_M ------------MTATS---------------------------------
MUL_1631|M.ulcerans_Agy99 ------------MTATS---------------------------------
MAV_3124|M.avium_104 ------------MTGRS---------------------------------
Mflv_3536|M.gilvum_PYR-GCK ------------MANDSLSPEGSETPEG------------------AAQP
Mvan_3322|M.vanbaalenii_PYR-1 ------------MADS---------------------------------P
MSMEG_3781|M.smegmatis_MC2_155 ------------MATR-------------------------------ATS
TH_1589|M.thermoresistible__bu -VTEQLGLCEVPMAAKSTTSRNRRSDAGGAGAQDFPADTPRPEPRPGPSG
MAB_0757|M.abscessus_ATCC_1997 MVNDMSELAKVQPAAESGAFVSGCPVSHG--------------------T
:
Rv1645c|M.tuberculosis_H37Rv -RTSADPLGPDSLTWKYFGDLRTGMMGVWIGAIQNMYPELGAGVEEHSIL
Mb1672c|M.bovis_AF2122/97 -RTSADPLGPDSLTWKYFGDLRTGMMGVWIGAIQNMYPELGAGVEEHSIL
MMAR_2452|M.marinum_M -PPAANPLGPDSLTWKYFGDLRTGMMGVWIGAIQNMYPELGAGVTEHSIL
MUL_1631|M.ulcerans_Agy99 -PPAANPLGPDSLTWKYFGDLRIGMMGVWIGAIQNMYPELGAGVTEHSIL
MAV_3124|M.avium_104 -TTAADPLGPDSLTWKYFGDLRTGMMGVWIGAIQNMYPELGAGVQEHSIL
Mflv_3536|M.gilvum_PYR-GCK QAPGAFPLGPDSLTWKYFGDVRTGILGVWIGAIQNMYPQLGAGVEDHSIL
Mvan_3322|M.vanbaalenii_PYR-1 PAAGADPLGPDSLTWKYFGDVRTGMLGVWVGAIQNMYPQLGAGVEDHSIL
MSMEG_3781|M.smegmatis_MC2_155 TDTASDPLGLDSLTWKYFGDLRTGMLGVWIGAIQNMYPELGAGVEEHSIL
TH_1589|M.thermoresistible__bu TTPAAQPLGPDSLTWKYFGDLRTGLLGVWIGAIQNMYPELGAGVTDHSIV
MAB_0757|M.abscessus_ATCC_1997 GKSMPVPLGPESLTWKYFGDWRGMLQGPYAGSMQNMHPQLGAAVEQHSQF
. . *** :********* * : * : *::***:*:***.* :** .
Rv1645c|M.tuberculosis_H37Rv LREPLQRVARSVYPIMGVVYDGDRAAQTGQQIKGYHRTIKGVDAEGRRYH
Mb1672c|M.bovis_AF2122/97 LREPLQRVARSVYPIMGVVYDGDRAAQTGQQIKGYHRTIKGVDAEGRRYH
MMAR_2452|M.marinum_M LREPLQRVARSVYPIMGVVYDGDRAAQTGQQIKGYHRTIKGVDADGRRYH
MUL_1631|M.ulcerans_Agy99 LREPLQRVARSVYPIMGVVYDGDRAAQTGQQIKGYHRTIKGVDADGRRYH
MAV_3124|M.avium_104 LREPLQRVARSVYPIMGVVYDGDRAPQTGRQITSYHHTIKGTDASGRRYH
Mflv_3536|M.gilvum_PYR-GCK MREPLQRVARSVYPIMGVVYDGDRAAQTGAQIRGYHKTIKGVDADGRRYH
Mvan_3322|M.vanbaalenii_PYR-1 LREPLQRVARSVYPIMGVVYDGDRAAQTGAQIRGFHKTIKGADSDGRRYH
MSMEG_3781|M.smegmatis_MC2_155 LREPLQRVARSVYPIMGVVYDGDRAPETGAQIKGFHKTIKGVDSSGRRYH
TH_1589|M.thermoresistible__bu LQEPLQRVARSVYPIMGVVYDGDRAPLTGAQIKSYHRDIKGVDAAGRRYH
MAB_0757|M.abscessus_ATCC_1997 FRERWQRLLRSLYPIGGVVFDGDRAPMTGAEVRDYHVNIKGVDDQGRRYS
::* **: **:*** ***:*****. ** :: .:* ***.* ****
Rv1645c|M.tuberculosis_H37Rv ALNPDTFYWAHATFFMLVIKVAEYFCGGLTEAEKHQLFEEHVRWYRMYGM
Mb1672c|M.bovis_AF2122/97 ALNPDTFYWAHATFFMLVIKVAEYFCGGLTEAEKHQLFEEHVRWYRMYGM
MMAR_2452|M.marinum_M ALNPETFYWAHATFFMLVVKVAEYFCGGLTEAEKRQLFDEHVQWYRMYGM
MUL_1631|M.ulcerans_Agy99 ALNPETFYWAHATFFMLVVKVAEYFCGGLTEAEKRQLFDEYVQWYRMYGM
MAV_3124|M.avium_104 ALNPDTFYWAHATFFMLIIKVAEYFCGGLTEAEKRQLFDEHVQWYRMYGM
Mflv_3536|M.gilvum_PYR-GCK ALNPETFYWAHATFFMLIIKTAEYFCGGLTEAEKEQLFDEHVQWYRMYGM
Mvan_3322|M.vanbaalenii_PYR-1 ALNPETFYWAHATFFMLIIKTAEYFCGGLTEAEKRQLFDEHVQWYRMYGM
MSMEG_3781|M.smegmatis_MC2_155 ALNPETFYWAHATFFMLIIKTAEYFCGGLTEAEKRQLFDEHVQWYRMYGM
TH_1589|M.thermoresistible__bu ALNPETFYWAHATFFMLILKTAEYFCGGLTEAEKHQLFDEHVRWYRMYGM
MAB_0757|M.abscessus_ATCC_1997 ALNPDVFYWAHATFFMGTIIVAERFCGGITEAEKRQLFDEHITWYQMYGM
****:.********** : .** ****:*****.***:*:: **:****
Rv1645c|M.tuberculosis_H37Rv SMRPVPKSWEDFQDYWDRVCRDKLEINQATVDILQMR-IPKPRFV-LMPT
Mb1672c|M.bovis_AF2122/97 SMRPVPKSWEDFQDYWDRVCRDKLEINQATVDILQMR-IPKPRFV-LMPT
MMAR_2452|M.marinum_M SMRPVPETWEDFQDFWERVGRDELEINQATLDIFNMR-IPKPKFV-LMPT
MUL_1631|M.ulcerans_Agy99 SMRPVPETWEDFQDFWERVGRDELEINQATLDIFNMR-IPKPKFV-LMPI
MAV_3124|M.avium_104 SMRPVPKSWEEFQEYWERTGREVLEINQATLDIFRMR-IPKPKFV-LMPT
Mflv_3536|M.gilvum_PYR-GCK SMAPVPESWQAFCEYWDRKCREELEINSATLDILSMR-IPKPWFV-LMPT
Mvan_3322|M.vanbaalenii_PYR-1 SMQPVPESWEAFCEYWDRKCREELEINKATLDIFSMR-IPKPWFV-MMPT
MSMEG_3781|M.smegmatis_MC2_155 SMRPVPQTWEEFQDYWDAKCRDELEINRATLDIFSIR-IPKPWFV-LMPT
TH_1589|M.thermoresistible__bu SMRPVPRTWEEFCEYWDRTCREQLEINQAALDILHIR-IPKPWFV-LMPT
MAB_0757|M.abscessus_ATCC_1997 SMRPVPKSWEEFQEYWDHMCTNVLEDNKATRDVLDLTTLAVPPFAPWIPK
** ***.:*: * ::*: : ** * *: *:: : :. * *. :*
Rv1645c|M.tuberculosis_H37Rv PIWDQLFKPLIAGQRWIAAGLFDPAVREKAGMHWTPGDEVLLRVFGKVVE
Mb1672c|M.bovis_AF2122/97 PIWDQLFKPLIAGQRWIAAGLFDPAVREKAGMHWTPGDEVLLRVFGKVVE
MMAR_2452|M.marinum_M GIWDQLFRPLVAGQRWIAAGLFEPAVREKAGMHWTQGDEVLLRLFGKAVE
MUL_1631|M.ulcerans_Agy99 GIWDQLFRPLVAGQRWIAAGLFEPAVREKAGMHWTQGDEVLLRLFGKAVE
MAV_3124|M.avium_104 PLWDQLFRPLVAGQRWIAAGLFEPAVREKAGMHWTPGDEVLLRLFGKIVE
Mflv_3536|M.gilvum_PYR-GCK PVWDQMFKPMIGAQRWIAAGVFDPVVRERAGMRWTPGDEIVLRLFGKMVE
Mvan_3322|M.vanbaalenii_PYR-1 PLWDQIFKPMVGAQRWIAAGVFDPVVRERAGMRWTPGDEIVLRLFGKLVE
MSMEG_3781|M.smegmatis_MC2_155 PIWDQLFKPLVGAQRWIAAGLFDPVVREKAGMRWTPGDEVLLRIFGKAVE
TH_1589|M.thermoresistible__bu PVWDQLFRPLLAGQRWVAAGVFEPVLREKAGMRWTPGDEVLLRLFGKLVE
MAB_0757|M.abscessus_ATCC_1997 WLWALQRRMLSPFFVWFTVGLYDPPVRKRLGYTWSDRDEWLHRSFGRLVN
:* : : *.:.*:::* :*:: * *: ** : * **: *:
Rv1645c|M.tuberculosis_H37Rv LAFLAVPDEIRLHPRALAAYRRAAGRTRHDAPLVQAPGFMAPPRDRQGLP
Mb1672c|M.bovis_AF2122/97 LAFLAVPDEIRLHPRALAAYRRAAGRTRHDAPLVQAPGFMAPPRDRQGLP
MMAR_2452|M.marinum_M LAFLAVPDEIRLHPRALAAYRRAEGRVKRDAPLVEAPSFMAPPSDRRGLP
MUL_1631|M.ulcerans_Agy99 LAFLAVPDEIRLHPRALAAYRRAEGRVKRDAPLVEAPSFMAPPSDRRGLP
MAV_3124|M.avium_104 LAFLAVPDEIRLHPRALAAYRREQGRLPSDAPLVEAPPFMAPPRDRRGLP
Mflv_3536|M.gilvum_PYR-GCK LAFVAVPDEIRLHPRAVAAYRRAEGKVPADAPLVEAPAFMAPPRDRRSMP
Mvan_3322|M.vanbaalenii_PYR-1 LAFLAVPDEIRLHPRAVAAYRRAEGKIPADAPLVEAPAFMAPPRDRRHMP
MSMEG_3781|M.smegmatis_MC2_155 LAFLAVPDEIRLHPRAVSAYRRAKGRIPADAPLVEAPGFTAPPKDRRGLP
TH_1589|M.thermoresistible__bu LAFVAVPDEIRLHPRALSAYRRASGRIPADAPLVEAPAFTGPPGDRRGLP
MAB_0757|M.abscessus_ATCC_1997 VVFRFVPERFRRHPRARAGWDRALGRIPADAPLPQTPDRNLPPLDTWGSP
:.* **:.:* **** :.: * *: **** ::* ** * *
Rv1645c|M.tuberculosis_H37Rv MHYFPPRSHRFTRSALDPAKALMERAGALVHSTLSLAGVRPARGPSRAA-
Mb1672c|M.bovis_AF2122/97 MHYFPPRSHRFTRSALDPAKALMERAGALVHSTLSLAGVRPARGPSRAA-
MMAR_2452|M.marinum_M MHYFPPRAH--------PAKVLLERAGSLVHSTLSIAGLRPARGRSRTTT
MUL_1631|M.ulcerans_Agy99 MHYFPPRAH--------PAKVLLERAGSLVHSTLSIAGLQPARGRSRTTT
MAV_3124|M.avium_104 MHYFPPPPRLPFDPALQPARALMERAGSLVHTTLSLAGLRAGRGRPKRPV
Mflv_3536|M.gilvum_PYR-GCK MHYLP------------PRKTLLDRVGSLVHSTFSLAGRRPARGTG---K
Mvan_3322|M.vanbaalenii_PYR-1 MHYLP------------PQKSLLDRVGSLVHTTFSLAGVRPARKPG---K
MSMEG_3781|M.smegmatis_MC2_155 MHYLP------------QRRSLLDRAGALVHSTLSLPALRPAKKSSPRRS
TH_1589|M.thermoresistible__bu MHYVP------------RRRSLIERAGALVHSTFSLAGLRPARGSAA---
MAB_0757|M.abscessus_ATCC_1997 NHYNP---------------------------KVS---------------
** * ..*
Rv1645c|M.tuberculosis_H37Rv ---
Mb1672c|M.bovis_AF2122/97 ---
MMAR_2452|M.marinum_M AA-
MUL_1631|M.ulcerans_Agy99 AA-
MAV_3124|M.avium_104 RAA
Mflv_3536|M.gilvum_PYR-GCK AA-
Mvan_3322|M.vanbaalenii_PYR-1 AA-
MSMEG_3781|M.smegmatis_MC2_155 AA-
TH_1589|M.thermoresistible__bu ---
MAB_0757|M.abscessus_ATCC_1997 ---