For questions or suggestions e-mail us at: ioerger@cs.tamu.edu
MAYLTVFPDMLAGAAGDLVGIGSQLAAANTAAIGPTTTVLAAGADEVSAAIAAVFSGHGQAYQVLSAQVA AFHQRFVEALNAGAQSYVGAEAANATPLQTLEQDALGIINAPTQALVGRPLIGNGANGTAANPNGGDGGL LYGNGGNGFAQTGNNNVAGGDGGNAGLIGNGGAGGGGGTAFAGGKGGHGGLLYGNGGAGGIGGDGTGNGF GSLSGGGNGGAGAPGLSGLGGAGGRGGYLIGSGGNGGAGAGGGDGGYLSGNGGNGGDGVIAGNGSAGGAG GNALGLFGHGGAGGAGGYDVTTQAGLTGGNGGVGGKLIGDGGLGGDGGIGLAGTGGNGGNGGDAVGVIGN GGVGGAGGVGAFGSGGTGGNGGAGGAVGNGGAGGDAGSSGNLSPAGDGKGGNAKLVGNGGDGGAGVFGGL GGDGGTGGQLFGNMGLNGPA
Operon Prediction Model: Genebank
Paralogs
species | id | gene | e-value | identity (len) | annotation |
M. ulcerans Agy99 | MUL_4489 | - | - | 100% (440) | PE-PGRS family protein |
M. ulcerans Agy99 | MUL_3507 | - | e-126 | 51.47% (509) | PE-PGRS family protein |
M. ulcerans Agy99 | MUL_4399 | - | e-123 | 52.34% (491) | PE-PGRS family protein |
Closest Orthologs (e-value cutoff: 1e-4)
species | id | gene | e-value | identity (len) | annotation |
M. bovis AF2122 / 97 | Mb2186c | PE_PGRS38 | 1e-124 | 51.50% (501) | hypothetical protein Mb2186c |
M. gilvum PYR-GCK | Mflv_5091 | - | 1e-70 | 40.17% (458) | triple helix repeat-containing collagen |
M. tuberculosis H37Rv | Rv0124 | PE_PGRS2 | 1e-126 | 54.99% (471) | PE-PGRS family protein |
M. leprae Br4923 | MLBr_01183 | - | 4e-13 | 38.04% (92) | hypothetical protein MLBr_01183 |
M. abscessus ATCC 19977 | MAB_4284c | - | 5e-36 | 33.58% (408) | hypothetical protein MAB_4284c |
M. marinum M | MMAR_4186 | - | 0.0 | 69.31% (492) | PE-PGRS family protein |
M. avium 104 | MAV_4827 | - | 4e-20 | 38.82% (170) | hypothetical protein MAV_4827 |
M. smegmatis MC2 155 | MSMEG_0868 | - | 4e-66 | 46.65% (328) | hypothetical protein MSMEG_0868 |
M. thermoresistible (build 8) | TH_3810 | - | 5e-38 | 39.80% (294) | PUTATIVE - |
M. vanbaalenii PYR-1 | Mvan_1264 | - | 2e-70 | 42.70% (452) | triple helix repeat-containing collagen |
CLUSTAL 2.0.9 multiple sequence alignment Mflv_5091|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_1264|M.vanbaalenii_PYR-1 -------------------------------------------------- MSMEG_0868|M.smegmatis_MC2_155 MHERLRERAGGVRKTLSDFAEGAGLKPSDTDDTRSPLRKPKFPAALAPES TH_3810|M.thermoresistible__bu -------------------------------------------------- MUL_4489|M.ulcerans_Agy99 -------------------------------------------------- MMAR_4186|M.marinum_M -------------------------------------------------- Mb2186c|M.bovis_AF2122/97 -------------------------------------------------- Rv0124|M.tuberculosis_H37Rv -------------------------------------------------- MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAB_4284c|M.abscessus_ATCC_199 -------------------------------------------------- MAV_4827|M.avium_104 -------------------------------------------------- Mflv_5091|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_1264|M.vanbaalenii_PYR-1 -------------------MMFLAPPGGPGPISAAIQLTSTGSEATEP-- MSMEG_0868|M.smegmatis_MC2_155 PLPDLKPRWERPTTAPDSETPSITQPQGRDTAADPAEQQATSTNTTDQPT TH_3810|M.thermoresistible__bu -------------------------------------------------- MUL_4489|M.ulcerans_Agy99 -------------------------------------------------- MMAR_4186|M.marinum_M -------------------------------------------------- Mb2186c|M.bovis_AF2122/97 -------------------------------------------------- Rv0124|M.tuberculosis_H37Rv -------------------------------------------------- MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAB_4284c|M.abscessus_ATCC_199 -------------------------------------------------- MAV_4827|M.avium_104 -------------------------------------------------- Mflv_5091|M.gilvum_PYR-GCK --------------------------------------MVTFGGGATPTP Mvan_1264|M.vanbaalenii_PYR-1 ------------------------------------WYVVSFGGSGAPTP MSMEG_0868|M.smegmatis_MC2_155 SDSLGAQPTAQVARQVQAPATDPAPAAPSLRPISGLLSVVTLGTTLIPNA TH_3810|M.thermoresistible__bu -------------------------------------------------- MUL_4489|M.ulcerans_Agy99 -------------------------------------------------- MMAR_4186|M.marinum_M -------------------------------------------------- Mb2186c|M.bovis_AF2122/97 -------------------------------------------------- Rv0124|M.tuberculosis_H37Rv -------------------------------------------------- MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAB_4284c|M.abscessus_ATCC_199 -------------------------------------------------- MAV_4827|M.avium_104 -------------------------------------------------- Mflv_5091|M.gilvum_PYR-GCK ----------------------------------------TSLGAAAVDL Mvan_1264|M.vanbaalenii_PYR-1 ----------------------------------------NNLAASLVDL MSMEG_0868|M.smegmatis_MC2_155 PTEPADMPGVWAVMAWARRQPMYSDPAMRTTVNPQAQLPVPTVASAVLDP TH_3810|M.thermoresistible__bu -------------------------------------------------- MUL_4489|M.ulcerans_Agy99 -------------------------------------------------- MMAR_4186|M.marinum_M -------------------------------------------------- Mb2186c|M.bovis_AF2122/97 -------------------------------------------------- Rv0124|M.tuberculosis_H37Rv -------------------------------------------------- MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAB_4284c|M.abscessus_ATCC_199 -------------------------------------------------- MAV_4827|M.avium_104 -------------------------------------------------- Mflv_5091|M.gilvum_PYR-GCK S------------------------GTSCG----------LICNGQDGTG Mvan_1264|M.vanbaalenii_PYR-1 S------------------------GTSCG----------LICNGQDGTG MSMEG_0868|M.smegmatis_MC2_155 TQIVNWLIYQPLHAAGQQFWVVSPIGSTLGGVINTISGQYLIGNGINGTA TH_3810|M.thermoresistible__bu -------------------------------------------------- MUL_4489|M.ulcerans_Agy99 -------------------------------------------------- MMAR_4186|M.marinum_M -------------------------------------------------- Mb2186c|M.bovis_AF2122/97 -------------------------------------------------- Rv0124|M.tuberculosis_H37Rv -------------------------------------------------- MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAB_4284c|M.abscessus_ATCC_199 -------------------------------------------------- MAV_4827|M.avium_104 -------------------------------------------MNIVLGV Mflv_5091|M.gilvum_PYR-GCK QN-----GGILFGNGGSGWNSDVVGMDGGNGGNGGLFGGNGGNGGNGLGG Mvan_1264|M.vanbaalenii_PYR-1 QN-----GGILFGNGGSGWNSEIAGVSGGNGGNAGLFGGNGGNGGNGLGS MSMEG_0868|M.smegmatis_MC2_155 DNPNGGTGGLLFGDGGHGYDGSAAGLAGGNGGNAGLFG-NGGNGGVGWAG TH_3810|M.thermoresistible__bu ------------------------------------------------VD MUL_4489|M.ulcerans_Agy99 -----------MAYLTVFPDMLAGAAGDLVGIGSQLAAANTAAIGPTTTV MMAR_4186|M.marinum_M -----------MAYLTVFPDMLAGAAGDLVGIGSQLAAANTAAIGPTTTV Mb2186c|M.bovis_AF2122/97 -----------MSFVIAAPEVMAAAATDLANIGSSISAASAAAAGPTMGI Rv0124|M.tuberculosis_H37Rv -----------MSFVSVAPEIVVAAATDLAGIGSAISAANAAAAAPTTAV MLBr_01183|M.leprae_Br4923 ----------MPLFLNAEPQALTAAANTLEGLSAATVASNAAAAQLTTEI MAB_4284c|M.abscessus_ATCC_199 ---MSIIDFILNLFRDPVEAASYVADPEAALANAGLSAVSAAQVGAVMPV MAV_4827|M.avium_104 SMAPSSIQMVVLEGEYADGATVEEDAIDVTGADDAATASAPDRVISAILG Mflv_5091|M.gilvum_PYR-GCK GNGGNGGNAGAFALFGNGGNGGNGGVGVVGATGAVG--APGVAGATGATG Mvan_1264|M.vanbaalenii_PYR-1 GDGGNGGDAGLFSLFGRGGNGGNGGVGIAGATGAVG--APGVAGATGATG MSMEG_0868|M.smegmatis_MC2_155 LDGGNGGSGG--LLMGIGGAGGAGGVGADGTSAHVDGGTGGTGGTGGGTG TH_3810|M.thermoresistible__bu GDGGSGGRTGLFSKLSRGGDGGDGGLG-------------GNGGHGGGTG MUL_4489|M.ulcerans_Agy99 LAAGADEVSAAIAAVFSGHGQAYQVLSAQVAAFHQRFVEALNAGAQSYVG MMAR_4186|M.marinum_M LAAGADEVSAAIAAVFSGHGQAYQVLSAQVAAFHQRFVEALNAGAQSYVG Mb2186c|M.bovis_AF2122/97 LAAGADEVSVAISALFGSHAQGYQTLSAQLAAYHNQFVRALNAGAGSYAS Rv0124|M.tuberculosis_H37Rv LAAGADEVSAAIAALFSGHAQAYQALSAQAAAFHQQFVQTLAGGAGAYAA MLBr_01183|M.leprae_Br4923 APPAADDVSILLAHFFSGHGRQYQAHASQGATNHQDLIQSLLTSSSAYAG MAB_4284c|M.abscessus_ATCC_199 VAESVASNYGYQSQWVNTGNPIHDLSGNLQNYYAAQPDGPSILSPSLLSP MAV_4827|M.avium_104 TREGAADAGLQLSSIGVTWTDQLEAAALRDALAARRIDNVMLVSAFLAAA . . . Mflv_5091|M.gilvum_PYR-GCK VTSGVVGGNGEDAVGYGATGAAGAAGAAGAAGAAG--------------A Mvan_1264|M.vanbaalenii_PYR-1 VTSNVTGGNGADAVGYGATGAAGAAGAAGAAGKAG--------------A MSMEG_0868|M.smegmatis_MC2_155 GTGGIGGTGGGLFGLLGHSGSTGAAGAAGNGGDGGNGGFGYVLIAGPNVT TH_3810|M.thermoresistible__bu IIS--------------------LLSLAGNGGNGG--------------- MUL_4489|M.ulcerans_Agy99 AEAANATPLQTLEQDALGIINAPTQALVGRPLIGN--------------- MMAR_4186|M.marinum_M AEAANATPLQTLEQDALGIINAPTQALVGRPLIGN--------------- Mb2186c|M.bovis_AF2122/97 AEAAN------VQQTLLNAINAPTQTLLGRPLIGN--------------- Rv0124|M.tuberculosis_H37Rv AEAQ-------VEQQLLAAINAPTQALLGRPLIGN--------------- MLBr_01183|M.leprae_Br4923 TETAN--------HDSL--------------------------------- MAB_4284c|M.abscessus_ATCC_199 RDNDFLSHNDTDFASHNPIASGNQVMSPSGNVDSFNRGPLLDLSFGDLQF MAV_4827|M.avium_104 ALAQNVGGAMGYERTAVLLVEPDTATLAVVETSDGS------------IP Mflv_5091|M.gilvum_PYR-GCK VGSAGAAGEAGETGTWG--NAGLPGKAGDAGGAG---------------- Mvan_1264|M.vanbaalenii_PYR-1 VGSAGTAGSAGAPGVWG--NAGLPGAAGAAGGAG---------------- MSMEG_0868|M.smegmatis_MC2_155 VGSETRGGTGGAGGTGGQSTAAGPGKGGGGGGGGGGAILIGANGGTVDGH TH_3810|M.thermoresistible__bu NGYRTTDNNALDGGHGG--------------------------------- MUL_4489|M.ulcerans_Agy99 -GANGTA-ANPNGGDGGLLYGNGGNGFAQTGNNNVA-------------- MMAR_4186|M.marinum_M -GANGTA-ANPNGGDGGLLYGNGGNGFTQTGNNNVA-------------- Mb2186c|M.bovis_AF2122/97 -GADGGP--GQNGGPGGLLYGNGGNGGAGD-TANPN-------------- Rv0124|M.tuberculosis_H37Rv -GADGAPGTGQAGGAGGILYGNGGNGGSG--AAGQA-------------- MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAB_4284c|M.abscessus_ATCC_199 GNRDTTAIGDGAVAVGGSNSGPIASGQGSTAVNGDVR------------- MAV_4827|M.avium_104 DVYKQQIRAESYGDAAGQLSAMVAGLEKLESLPGGLLLVG---------- Mflv_5091|M.gilvum_PYR-GCK AVGAAGAAG------TVGTAGATGGTG---------------TGANGGAG Mvan_1264|M.vanbaalenii_PYR-1 AIGTAGVAG------AAGTAGATGGTG---------------VGGNGGAG MSMEG_0868|M.smegmatis_MC2_155 AIGGNGGNGGNGSTTAAGGNGGTGGTGRVIAEGTGSTAEGTATGGDGGHS TH_3810|M.thermoresistible__bu ------------------------------------------NGGNVGFF MUL_4489|M.ulcerans_Agy99 -------------------------------------------GGDGGNA MMAR_4186|M.marinum_M -------------------------------------------GGNGGNA Mb2186c|M.bovis_AF2122/97 -------------------------------------------GGNGGSA Rv0124|M.tuberculosis_H37Rv -------------------------------------------GGAGGPA MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAB_4284c|M.abscessus_ATCC_199 --------------------------------------DSNIINADHGSN MAV_4827|M.avium_104 -----------------------SGVDVAPLKQVLQTTTFLDVSVAEEPE Mflv_5091|M.gilvum_PYR-GCK GVGGVGGTGAAG--------------AAGGAGGLGETGTTGGAGGVGGQ- Mvan_1264|M.vanbaalenii_PYR-1 QAGGIGGTGAAG--------------AAGQAGTAGETGVTGGVGGIGGQ- MSMEG_0868|M.smegmatis_MC2_155 TGTGIGGNGGIGSVYAYGNNGAVSGTATGGRGGDGIDGGTGGAGGMGEIY TH_3810|M.thermoresistible__bu SLFNLGG--------------------AGGWGGSGVDG------------ MUL_4489|M.ulcerans_Agy99 GLIGNGGAGGGGG-------------TAFAGGKGGHGGLLYGNGGAGGIG MMAR_4186|M.marinum_M GLIGNGGAGGGGG-------------TAFAGGNGGHGGLLYGNGGAGAIG Mb2186c|M.bovis_AF2122/97 GLIGNGGAGGAGA-------------ATGAGGAGGNGGWLYGNGGPGGAA Rv0124|M.tuberculosis_H37Rv GLIGHGGSGGAGG-------------SGAAGGAGGHGGWLWGNGGVGGSG MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAB_4284c|M.abscessus_ATCC_199 VGVDQSQTRVGGDYTN-----------VSGHGSADIDKSVTVVDDHSQRN MAV_4827|M.avium_104 TALARGAALAAAN-APLFASSTAALAYAQDPGTGAVDQYSLPDYLYVPVD Mflv_5091|M.gilvum_PYR-GCK -GTAGGTGGVGGIGGAGSTGAVGGVGGKG----IQGGQG----------- Mvan_1264|M.vanbaalenii_PYR-1 -GTEGGTGGVGGVGGVGATGGAGGVGGKG----IQGGQG----------- MSMEG_0868|M.smegmatis_MC2_155 SGADGEATGISAGGDGGSATGADSLGGRGGTSWVQAGYGPTT-------- TH_3810|M.thermoresistible__bu ---------VDVVGGNP--------------------------------- MUL_4489|M.ulcerans_Agy99 GDGTGNGFGSLSGGGNGG-------------------------------- MMAR_4186|M.marinum_M GDGTGNGFGSLSGGGNGGSGGGAGLWGVGGAGGNGGAGGSPTVPGHAGGN Mb2186c|M.bovis_AF2122/97 GLGTAGGVSP-AGGAGG--------------------------------- Rv0124|M.tuberculosis_H37Rv GAGVGAGVAGGHGGAGG--------------------------------- MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAB_4284c|M.abscessus_ATCC_199 TTNINDSFNTDRSTNIGSGNTTNTEIGSHN-------------------- MAV_4827|M.avium_104 PEPGDDELAYSAVGEEDAESPTVVIEKLFLP------------------- Mflv_5091|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_1264|M.vanbaalenii_PYR-1 -------------------------------------------------- MSMEG_0868|M.smegmatis_MC2_155 -------------------------------------------------- TH_3810|M.thermoresistible__bu -------------------------------------------------- MUL_4489|M.ulcerans_Agy99 -------------------------------------------------- MMAR_4186|M.marinum_M GGSGGIGGAGGVFGNGGAGGNGGIGGTGGTGGNGGIGGNGAAGGAGGLWG Mb2186c|M.bovis_AF2122/97 -------------------------------------------------- Rv0124|M.tuberculosis_H37Rv -------------------------------------------------- MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAB_4284c|M.abscessus_ATCC_199 -------------------------------------------------- MAV_4827|M.avium_104 -------------------------------------------------- Mflv_5091|M.gilvum_PYR-GCK ---------------------------------------LQGGKGGDGGA Mvan_1264|M.vanbaalenii_PYR-1 ---------------------------------------LQGGQGGDGGT MSMEG_0868|M.smegmatis_MC2_155 -----------------------------GGKASGTAKAGHGGKASDGGK TH_3810|M.thermoresistible__bu ----------------------------------------------DGGT MUL_4489|M.ulcerans_Agy99 -------------------------------------------------- MMAR_4186|M.marinum_M DGGVGGNGAVGGNSGGGFGVMNDGGSGGHGGDARLFGNGGNGGAGAVGGA Mb2186c|M.bovis_AF2122/97 -------------------------------------------------- Rv0124|M.tuberculosis_H37Rv -------------------------------------------------- MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAB_4284c|M.abscessus_ATCC_199 -------------------------------------------------- MAV_4827|M.avium_104 -------------------------------------------------- Mflv_5091|M.gilvum_PYR-GCK GGKGGDADSMGS------------------AGATGGKGGNGGNGGRGGLF Mvan_1264|M.vanbaalenii_PYR-1 GGTGGDATSMGE------------------AGATGGKGGNGGNGGRGSLF MSMEG_0868|M.smegmatis_MC2_155 GGNGGDALVMAAGATGVATGNTAIGGNGGAASANGAVGGNGGFTNIAAIH TH_3810|M.thermoresistible__bu PG------------------------------AHGESHTPGVYTDRQ--- MUL_4489|M.ulcerans_Agy99 -------------------------------------------------- MMAR_4186|M.marinum_M GGNGADGGIGGQFFGNGGDGGAGGIGTAGLAGSGGTGGSAVGLVGNGGTG Mb2186c|M.bovis_AF2122/97 -------------------------------------------------- Rv0124|M.tuberculosis_H37Rv -------------------------------------------------- MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAB_4284c|M.abscessus_ATCC_199 -------------------------------------------------- MAV_4827|M.avium_104 -------------------------------EDSEPRRRPVLLVGSG--- Mflv_5091|M.gilvum_PYR-GCK G---------------KGGNAGNGAD----------------------GG Mvan_1264|M.vanbaalenii_PYR-1 G---------------RGGNAGNGGN----------------------GG MSMEG_0868|M.smegmatis_MC2_155 GSITDSSATSGHGGAAQGGNGGNGGNGWVQAYDPNGPAGTTIDKGKAAGG TH_3810|M.thermoresistible__bu -------------------------------------------------- MUL_4489|M.ulcerans_Agy99 -------------------------------------------------- MMAR_4186|M.marinum_M GAGGLGPIGGAGGNGGGGGLIGNGGNGGAGGAASATVGTPAPGVGGNGGA Mb2186c|M.bovis_AF2122/97 -------------------------------------------------- Rv0124|M.tuberculosis_H37Rv -------------------------------------------------- MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAB_4284c|M.abscessus_ATCC_199 -------------------------------------------------- MAV_4827|M.avium_104 -----------------------------------------------LAV Mflv_5091|M.gilvum_PYR-GCK TGGAGGAGGTGG-TGGAGGTGG-----------------TGGTGGIGGAG Mvan_1264|M.vanbaalenii_PYR-1 TGGNGGNGGTGG-TGGNGGTGG-----------------TGGTGGIGGAG MSMEG_0868|M.smegmatis_MC2_155 NGGDGGFNGTGGATGGRGGDGAGASVWKANGQHSTGQTDTGGNGGRGGDG TH_3810|M.thermoresistible__bu --GEDGEDGTGTGIGGRGGNGG----------------SSSGTHPMAEDG MUL_4489|M.ulcerans_Agy99 -----------AGAPGLSGLGG------------------AGGRGGYLIG MMAR_4186|M.marinum_M AGLFGDGGNGGAGAPGLSGLGG------------------AGGRGGYLIG Mb2186c|M.bovis_AF2122/97 -------------AAGLWGHGG------------------AGGAGGSASG Rv0124|M.tuberculosis_H37Rv -------------AAGLWGAGG------------------GGGNGGNGAD MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAB_4284c|M.abscessus_ATCC_199 -QANIGTSTSAGGSAAVGGNAG-----------------LAGNAGLAGNA MAV_4827|M.avium_104 VGISAVLALEIALAIGIRTTGTVALQPTPNQHLIVPTEQAPAPPPVQASA Mflv_5091|M.gilvum_PYR-GCK STGGTGGTGGTGGTGGTGGTG-GTGGTGGTGGTGGKGGTGGTGGAGGTG- Mvan_1264|M.vanbaalenii_PYR-1 STGGTGGTGGTGGTGGTGGTG-GTGGTGGTGGTGGKGGTGGTGGDGGTG- MSMEG_0868|M.smegmatis_MC2_155 GTFVNAGANGNGGAGGAGGVSEGEGGTGGHGGDGGRGGDGALGGNGGTGG TH_3810|M.thermoresistible__bu --------EHVKALDGRPGLD---GGNGSHGGNGGHGGRGGFLGIGGSG- MUL_4489|M.ulcerans_Agy99 S----GGNGGAGAGGGDGGYLSGNGGNGGDG------VIAGNGSAGGAGG MMAR_4186|M.marinum_M S----GGNGGAGAGGGDGGYLSGNGGNGGDG------VIVGNGSAGGAGG Mb2186c|M.bovis_AF2122/97 A----PGAGGAGGDGGRGGLLYGDGGAGGAGGNGSNGVTGVHGGNGGAGG Rv0124|M.tuberculosis_H37Rv ANIVSGGDGGLGGAGGGGGWLYGDGGAGGHGGQGAIGLGGGAGGDGGQGG MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAB_4284c|M.abscessus_ATCC_199 GLAGNAGLAGNAGLAGNAGLAGNAGLAGNAGLAGNAGLAGNAGLAGNAG- MAV_4827|M.avium_104 PQPKISVPEPVAAPKPLSPPVAAPLPAAPPPAAPPLPEAPPIPAAPPVVP Mflv_5091|M.gilvum_PYR-GCK ---GDGGTGGTGGTGGTG---------GTGGTGGTGGAG----------- Mvan_1264|M.vanbaalenii_PYR-1 ---GTGGTGGTGGTGGTG---------GTGGTGGTGGAG----------- MSMEG_0868|M.smegmatis_MC2_155 VGLGNGGKGGNGGNGGNGGTYVDPSHTGAGGNGGNGGAGRIRVNNGTATG TH_3810|M.thermoresistible__bu ------GWGGHGGNGGD-----------TDADGGNGGDG----------- MUL_4489|M.ulcerans_Agy99 NALGLFGHGGAGGAGGYDVT------TQAGLTGGNGGVGG---------- MMAR_4186|M.marinum_M NALGLFGHGGAGGAGGYDVT------TQAGLTGGNGGVGG---------- Mb2186c|M.bovis_AF2122/97 AA-GLIGNGGAGGDGGNGG------LSNTGASGGAGGAGGA--------- Rv0124|M.tuberculosis_H37Rv AGRGLWGTGGAGGHGGQGGGTGGPPLPGQAGMGAAGGAGG---------- MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAB_4284c|M.abscessus_ATCC_199 -LAGNAGLAGNAGLAGNAGLAGNAGLAGNAGLAGNAGLAGN--------- MAV_4827|M.avium_104 VPVVVPPVPVPVPVRIPVPDPVSPPQLLAPPRLSVPQPVQPPVRVPQPPS Mflv_5091|M.gilvum_PYR-GCK DGTGGTGGTGG----TGGQGGQGGQGG-----------------TGGTGG Mvan_1264|M.vanbaalenii_PYR-1 DGLGGTGGTGG----TGGFGGQGGQGG-----------------TGGTGG MSMEG_0868|M.smegmatis_MC2_155 TATGGNGGNGGNGDADGHRGGKGGDGGEALIRATVIGSNASGTATGGDGG TH_3810|M.thermoresistible__bu ----GNGGSAG---------------------------------RGGTGG MUL_4489|M.ulcerans_Agy99 -KLIGDGGLG------------------------------------GDGG MMAR_4186|M.marinum_M -KLIGDGGLG------------------------------------GDGG Mb2186c|M.bovis_AF2122/97 -ALIGNGGDGG---------------------------------HGGNGG Rv0124|M.tuberculosis_H37Rv --LIGNGGAG------------------------------------GDGG MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAB_4284c|M.abscessus_ATCC_199 AGLAGNAGLAG---------------------------------NAGLAG MAV_4827|M.avium_104 PPQVGGTVPQSP------------------------------PQHQTPPG Mflv_5091|M.gilvum_PYR-GCK QGG-LGGGGGTG-----------------------GQGGTGGTGGQGGTG Mvan_1264|M.vanbaalenii_PYR-1 QGG-LGGVGGTG-----------------------GTGGTGGTGGQGGTG MSMEG_0868|M.smegmatis_MC2_155 NGGTLGATNGTGGAATIVAYNVVQANPQASGTATDGHGGSGINGGHGGNG TH_3810|M.thermoresistible__bu LRGVFGINGGNG------------------------RAGLGGRGXXXXGG MUL_4489|M.ulcerans_Agy99 IGLAGTGGNGGN---------------------------GGDAVGVIGNG MMAR_4186|M.marinum_M IGLAGTGGNGGN---------------------------GGDAVGVIGNG Mb2186c|M.bovis_AF2122/97 HGNSGGAGGAGG---------------------------AGGHVGLIGNG Rv0124|M.tuberculosis_H37Rv VGASGGVAGVGG---------------------------AGGNAMLIGHG MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAB_4284c|M.abscessus_ATCC_199 NAGLAGNAAVAG------------------------NAAVAGNAAVAGNA MAV_4827|M.avium_104 EGTPPKPDGPGN--------------------------YGGGHVPTPGAG Mflv_5091|M.gilvum_PYR-GCK GTGGTGGTG--------GTGGAGGDGGLGG-----LGGFGGSGGTGGQGG Mvan_1264|M.vanbaalenii_PYR-1 GTGGTGGTG--------GTGGAGGDGGLGG-----LGGFGGVGGTGGQGG MSMEG_0868|M.smegmatis_MC2_155 GQGTIEANGPSAVASGIGAGGNGGDGIDGG-----LGGNGGDGVVNTTAN TH_3810|M.thermoresistible__bu GVGAAVRSG---------------NGVFSG-----GGGTPSAGFGVPTTI MUL_4489|M.ulcerans_Agy99 GVGGAGGVG------AFGSGGTGGNGGAGG-----AVGNGGAGGDAGSSG MMAR_4186|M.marinum_M GVGGAGGVG------AFGSGGTGGNGGAGG-----AVGNGGAGGDAGSSG Mb2186c|M.bovis_AF2122/97 GNGGAGGNGGNDNSSTLADAGSGGAGAAGGNG-GLFYGNGGVGGRGGNGG Rv0124|M.tuberculosis_H37Rv GAGGAGGD------SSFANGAAGGAGGAGG----HLFGNGGSGGHGG-AV MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAB_4284c|M.abscessus_ATCC_199 AVGGVLNTG--------VSGAIGGSSHVGGAINESLGGSGSVGGSTAVGG MAV_4827|M.avium_104 GSGGSGGGH-------VPTPGAGGSGGSGG-GHVPTPGTGGPGGTGGSGG Mflv_5091|M.gilvum_PYR-GCK LGGPGGSTGGAGGAGG--QAGTAGKGGLFG----GSGSAGKAGATGAAGA Mvan_1264|M.vanbaalenii_PYR-1 QGGPGGSTGGAGGAGG--QAGVAGKGGLFG----GSGSAGTAGVTGASGA MSMEG_0868|M.smegmatis_MC2_155 AANPGSATGTATGGDGGKATGTASQGGNGGPSWVQSGYGSTLGGNATGTA TH_3810|M.thermoresistible__bu QFPAGSCTSRAVSREG------------------------IMPSSRAASA MUL_4489|M.ulcerans_Agy99 NLSPAG----DGKGGNAKLVGNGGDGGAG-----------VFGGLGGDGG MMAR_4186|M.marinum_M NLSPAG----GGKGGNAKLVGNGGDGGAG-----------VFGGLGGDGG Mb2186c|M.bovis_AF2122/97 QAPTPGNAGDGGAGGNARLIGDGGRGGNGGEG--GDGPPGVKGD-GGNGG Rv0124|M.tuberculosis_H37Rv TAGNTGIGGAGGVGGDARLIGHGGAGGAGGDR--AGALVGRDGGPGGNGG MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAB_4284c|M.abscessus_ATCC_199 GAHTGVGGGVSTGVGVGSHVGGGISESLGGSG--SVGGSTAVGGGAHTGV MAV_4827|M.avium_104 GHVPTPGAGTPGGSGGGHLPFPGAGSTPGGSGGGHLPTPGAGTPGGGLGG Mflv_5091|M.gilvum_PYR-GCK SGGKGAQGATGAQGATG------AQGATG-ATGAAGKAGATGAAGAAGAA Mvan_1264|M.vanbaalenii_PYR-1 SGGKGAQGATGAQGATG------AQGATG-ATGASGAQGSAGSAGSAGVA MSMEG_0868|M.smegmatis_MC2_155 TAGKGGEASNGGVAGNGGNALVMAAGTTGVATGNTATGGDGGAATTAGAT TH_3810|M.thermoresistible__bu RAG---------------------------AACASSTSRSRRSFCCSRA- MUL_4489|M.ulcerans_Agy99 TGG------------------------------QLFGNMGLNGPA----- MMAR_4186|M.marinum_M TGG------------------------------QLFGNMGLNGPA----- Mb2186c|M.bovis_AF2122/97 NGGNAVVIGNGGNGGAGGFGIPVGSGGAGGSRGVLFGTPGANGADG---- Rv0124|M.tuberculosis_H37Rv AGG--QLYGNGGDGAPGTGGTLQAA--VSGLVTALFGAPGQPGDTGQPG- MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAB_4284c|M.abscessus_ATCC_199 GGGVSTGVGVGSHVGGG-------------ISESLGGSGSVGGSTAVGGG MAV_4827|M.avium_104 FGGGHAPAPGGGLGGGGG-----HAPAPGGGLGGFGGGHSGGGLGGLGGG Mflv_5091|M.gilvum_PYR-GCK GSAG-----------TTGAQGSAGTNGA-NGANGSQGAAGKAGATGTTGA Mvan_1264|M.vanbaalenii_PYR-1 GSAG-----------TTGAQGSAGTNGA-NGANGSQGAAGKAGATGTTGA MSMEG_0868|M.smegmatis_MC2_155 GGAGGFSNIAAIHGAITDSTAISGHGGAGNGGNGGKGADGWVQAYDPAGP TH_3810|M.thermoresistible__bu -------------------------------------------------- MUL_4489|M.ulcerans_Agy99 -------------------------------------------------- MMAR_4186|M.marinum_M -------------------------------------------------- Mb2186c|M.bovis_AF2122/97 -------------------------------------------------- Rv0124|M.tuberculosis_H37Rv -------------------------------------------------- MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAB_4284c|M.abscessus_ATCC_199 -----------------------AHTGVGGGVNTGVGVGSHVGGG----- MAV_4827|M.avium_104 HK------------------------------------------------ Mflv_5091|M.gilvum_PYR-GCK TG--------AAGEDGDAGSGGSG-INGGAGGAGG-----------AGGE Mvan_1264|M.vanbaalenii_PYR-1 TG--------AAGDAGDPGSEAVD-INGGAGGAGG-----------AGGE MSMEG_0868|M.smegmatis_MC2_155 VGSKIANSSAVAGNGGDGGVNGTGGASGGDGGNGGNTSVWKSGGQTADGE TH_3810|M.thermoresistible__bu -------------------------------------------------- MUL_4489|M.ulcerans_Agy99 -------------------------------------------------- MMAR_4186|M.marinum_M -------------------------------------------------- Mb2186c|M.bovis_AF2122/97 -------------------------------------------------- Rv0124|M.tuberculosis_H37Rv -------------------------------------------------- MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAB_4284c|M.abscessus_ATCC_199 ----------ISESLGGSGSVGGSTAVGGGAHTSAINDALGGSGSVGGST MAV_4827|M.avium_104 -------------------------------------------------- Mflv_5091|M.gilvum_PYR-GCK GGEGGDGGKGGAGAE--------GGAGGGGGAGGSGAGGAG--GAGGSGG Mvan_1264|M.vanbaalenii_PYR-1 GGEGGAGGAGGDGSE--------GGAGGSGGAGGSGTGGAG--GAGGSGG MSMEG_0868|M.smegmatis_MC2_155 HNTGGNGGNGGDGSEPGPGGNGAGGAGGNGGTGGTTAGGSGNGGNGGNGG TH_3810|M.thermoresistible__bu -------------------------------------------------- MUL_4489|M.ulcerans_Agy99 -------------------------------------------------- MMAR_4186|M.marinum_M -------------------------------------------------- Mb2186c|M.bovis_AF2122/97 -------------------------------------------------- Rv0124|M.tuberculosis_H37Rv -------------------------------------------------- MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAB_4284c|M.abscessus_ATCC_199 AVGGGAHTSAINESMNSSINASHSSSMNESFGSSMGSHGAAGTGFEAQGH MAV_4827|M.avium_104 -------------------------------------------------- Mflv_5091|M.gilvum_PYR-GCK SGGSGGSGGSGGAAGDSDD Mvan_1264|M.vanbaalenii_PYR-1 SGGSGGAGGSGGAAGDSD- MSMEG_0868|M.smegmatis_MC2_155 NGGADGTPGTAGTTGANNP TH_3810|M.thermoresistible__bu ------------------- MUL_4489|M.ulcerans_Agy99 ------------------- MMAR_4186|M.marinum_M ------------------- Mb2186c|M.bovis_AF2122/97 ------------------- Rv0124|M.tuberculosis_H37Rv ------------------- MLBr_01183|M.leprae_Br4923 ------------------- MAB_4284c|M.abscessus_ATCC_199 AQGHASETAHTTLPGAEHH MAV_4827|M.avium_104 -------------------