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MAYLTVFPDMLAGAAGDLVGIGSQLAAANTAAIGPTTTVLAAGADEVSAAIAAVFSGHGQAYQVLSAQVA AFHQRFVEALNAGAQSYVGAEAANATPLQTLEQDALGIINAPTQALVGRPLIGNGANGTAANPNGGDGGL LYGNGGNGFTQTGNNNVAGGNGGNAGLIGNGGAGGGGGTAFAGGNGGHGGLLYGNGGAGAIGGDGTGNGF GSLSGGGNGGSGGGAGLWGVGGAGGNGGAGGSPTVPGHAGGNGGSGGIGGAGGVFGNGGAGGNGGIGGTG GTGGNGGIGGNGAAGGAGGLWGDGGVGGNGAVGGNSGGGFGVMNDGGSGGHGGDARLFGNGGNGGAGAVG GAGGNGADGGIGGQFFGNGGDGGAGGIGTAGLAGSGGTGGSAVGLVGNGGTGGAGGLGPIGGAGGNGGGG GLIGNGGNGGAGGAASATVGTPAPGVGGNGGAAGLFGDGGNGGAGAPGLSGLGGAGGRGGYLIGSGGNGG AGAGGGDGGYLSGNGGNGGDGVIVGNGSAGGAGGNALGLFGHGGAGGAGGYDVTTQAGLTGGNGGVGGKL IGDGGLGGDGGIGLAGTGGNGGNGGDAVGVIGNGGVGGAGGVGAFGSGGTGGNGGAGGAVGNGGAGGDAG SSGNLSPAGGGKGGNAKLVGNGGDGGAGVFGGLGGDGGTGGQLFGNMGLNGPA
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. marinum M | MMAR_4186 | - | - | 100% (683) | PE-PGRS family protein |
| M. marinum M | MMAR_3316 | - | 0.0 | 52.28% (790) | PE-PGRS family protein |
| M. marinum M | MMAR_1207 | - | 0.0 | 51.33% (789) | PE-PGRS family protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1121 | PE_PGRS22 | 0.0 | 50.75% (800) | PE-PGRS family protein |
| M. gilvum PYR-GCK | Mflv_5091 | - | 1e-129 | 46.04% (632) | triple helix repeat-containing collagen |
| M. tuberculosis H37Rv | Rv1091 | PE_PGRS22 | 0.0 | 50.68% (803) | PE-PGRS family protein |
| M. leprae Br4923 | MLBr_01183 | - | 7e-13 | 38.04% (92) | hypothetical protein MLBr_01183 |
| M. abscessus ATCC 19977 | MAB_4284c | - | 8e-51 | 34.24% (517) | hypothetical protein MAB_4284c |
| M. avium 104 | MAV_4827 | - | 2e-22 | 43.53% (170) | hypothetical protein MAV_4827 |
| M. smegmatis MC2 155 | MSMEG_0868 | - | 1e-115 | 43.40% (712) | hypothetical protein MSMEG_0868 |
| M. thermoresistible (build 8) | TH_3810 | - | 6e-42 | 43.26% (282) | PUTATIVE - |
| M. ulcerans Agy99 | MUL_1145 | - | 1e-178 | 47.89% (852) | PE-PGRS family protein |
| M. vanbaalenii PYR-1 | Mvan_1264 | - | 1e-124 | 45.51% (646) | triple helix repeat-containing collagen |
CLUSTAL 2.0.9 multiple sequence alignment
TH_3810|M.thermoresistible__bu --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_1264|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_0868|M.smegmatis_MC2_155 MHERLRERAGGVRKTLSDFAEGAGLKPSDTDDTRSPLRKPKFPAALAPES
Mb1121|M.bovis_AF2122/97 --------------------------------------------------
Rv1091|M.tuberculosis_H37Rv --------------------------------------------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MUL_1145|M.ulcerans_Agy99 --------------------------------------------------
MMAR_4186|M.marinum_M --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 --------------------------------------------------
MAV_4827|M.avium_104 --------------------------------------------------
TH_3810|M.thermoresistible__bu --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_1264|M.vanbaalenii_PYR-1 -------------------MMFLAPPGGPGPISAAIQLTSTGSEATEP--
MSMEG_0868|M.smegmatis_MC2_155 PLPDLKPRWERPTTAPDSETPSITQPQGRDTAADPAEQQATSTNTTDQPT
Mb1121|M.bovis_AF2122/97 --------------------------------------------------
Rv1091|M.tuberculosis_H37Rv --------------------------------------------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MUL_1145|M.ulcerans_Agy99 --------------------------------------------------
MMAR_4186|M.marinum_M --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 --------------------------------------------------
MAV_4827|M.avium_104 --------------------------------------------------
TH_3810|M.thermoresistible__bu --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK --------------------------------------MVTFGGGATPTP
Mvan_1264|M.vanbaalenii_PYR-1 ------------------------------------WYVVSFGGSGAPTP
MSMEG_0868|M.smegmatis_MC2_155 SDSLGAQPTAQVARQVQAPATDPAPAAPSLRPISGLLSVVTLGTTLIPNA
Mb1121|M.bovis_AF2122/97 -----------------------------------------MS-FVIAAP
Rv1091|M.tuberculosis_H37Rv -----------------------------------------MS-FVIAAP
MLBr_01183|M.leprae_Br4923 -----------------------------------------MPLFLNAEP
MUL_1145|M.ulcerans_Agy99 -----------------------------------------MS-YVVASP
MMAR_4186|M.marinum_M -----------------------------------------MA-YLTVFP
MAB_4284c|M.abscessus_ATCC_199 ------------------------------------MSIIDFILNLFRDP
MAV_4827|M.avium_104 -------------------------------------MNIVLGVSMAPSS
TH_3810|M.thermoresistible__bu -------------------------------------VDGDGGSGGR---
Mflv_5091|M.gilvum_PYR-GCK ----------------------------------------TSLGAAAVDL
Mvan_1264|M.vanbaalenii_PYR-1 ----------------------------------------NNLAASLVDL
MSMEG_0868|M.smegmatis_MC2_155 PTEPADMPGVWAVMAWARRQPMYSDPAMRTTVNPQAQLPVPTVASAVLDP
Mb1121|M.bovis_AF2122/97 ----------------------------------------EALVAVASDL
Rv1091|M.tuberculosis_H37Rv ----------------------------------------EALVAVASDL
MLBr_01183|M.leprae_Br4923 ----------------------------------------QALTAAANTL
MUL_1145|M.ulcerans_Agy99 ----------------------------------------EYVAAAASDL
MMAR_4186|M.marinum_M ----------------------------------------DMLAGAAGDL
MAB_4284c|M.abscessus_ATCC_199 ----------------------------------------VEAASYVADP
MAV_4827|M.avium_104 ----------------------------------------IQMVVLEGEY
TH_3810|M.thermoresistible__bu -------------------------------------------TGLFSKL
Mflv_5091|M.gilvum_PYR-GCK S------------------------GTSCG----------LICNGQDGTG
Mvan_1264|M.vanbaalenii_PYR-1 S------------------------GTSCG----------LICNGQDGTG
MSMEG_0868|M.smegmatis_MC2_155 TQIVNWLIYQPLHAAGQQFWVVSPIGSTLGGVINTISGQYLIGNGINGTA
Mb1121|M.bovis_AF2122/97 AG----------------------------------------IGSALAEA
Rv1091|M.tuberculosis_H37Rv AG----------------------------------------IGSALAEA
MLBr_01183|M.leprae_Br4923 EG----------------------------------------LSAATVAS
MUL_1145|M.ulcerans_Agy99 AG----------------------------------------IGSALSTA
MMAR_4186|M.marinum_M VG----------------------------------------IGSQLAAA
MAB_4284c|M.abscessus_ATCC_199 EA-----------------------------------------ALANAGL
MAV_4827|M.avium_104 AD-----------------------------------------GATVEED
TH_3810|M.thermoresistible__bu SRGGDGGDGGLGGNGGHGGGTGIISLLSLAGNGGNGGNGYRTTDNNALDG
Mflv_5091|M.gilvum_PYR-GCK QN-----GGILFGNGGSGWNSDVVGMDGGNGGNGGLFGGNGGNGGNGLGG
Mvan_1264|M.vanbaalenii_PYR-1 QN-----GGILFGNGGSGWNSEIAGVSGGNGGNAGLFGGNGGNGGNGLGS
MSMEG_0868|M.smegmatis_MC2_155 DNPNGGTGGLLFGDGGHGYDGSAAGLAGGNGGNAGLFG-NGGNGGVGWAG
Mb1121|M.bovis_AF2122/97 NAAALAPTTALLAAGADEVSAAIAALFGAHGQAYQTVSAQASAFHAQFVQ
Rv1091|M.tuberculosis_H37Rv NAAALAPTTALLAAGADEVSAAIAALFGAHGQAYQTVSAQASAFHAQFVQ
MLBr_01183|M.leprae_Br4923 NAAAAQLTTEIAPPAADDVSILLAHFFSGHGRQYQAHASQGATNHQDLIQ
MUL_1145|M.ulcerans_Agy99 NAAAAAPTIEVLAAGADEVSAAIAAFFGAHAQAYQALSEQASAFHLQFVQ
MMAR_4186|M.marinum_M NTAAIGPTTTVLAAGADEVSAAIAAVFSGHGQAYQVLSAQVAAFHQRFVE
MAB_4284c|M.abscessus_ATCC_199 SAVSAAQVGAVMPVVAESVASNYGYQSQWVNTGNPIHDLSGNLQNYYAAQ
MAV_4827|M.avium_104 AIDVTGADDAATASAPDRVISAILGTREGAADAGLQLSSIGVTWTDQLEA
TH_3810|M.thermoresistible__bu GHGGNGGNVGFFSLFNLGGAGGWGGSGVDGVDVVGGNPDGGTPGAHGESH
Mflv_5091|M.gilvum_PYR-GCK GNGGNGGNAGAFALFGNGGNGGNGGVGVVGATGAVG--APGVAGATGATG
Mvan_1264|M.vanbaalenii_PYR-1 GDGGNGGDAGLFSLFGRGGNGGNGGVGIAGATGAVG--APGVAGATGATG
MSMEG_0868|M.smegmatis_MC2_155 LDGGNGGSGG--LLMGIGGAGGAGGVGADGTSAHVDGGTGGTGGTGGGTG
Mb1121|M.bovis_AF2122/97 ALTGGGGAYAAAEAANVSAAQSTDQRLLDLINGPTQALLGRPLIGDGANG
Rv1091|M.tuberculosis_H37Rv ALTGGGGAYAAAEAANVSAAQSTDQRLLDLINGPTQALLGRPLIGDGANG
MLBr_01183|M.leprae_Br4923 SLLTSSSAYAGTETANHDSL------------------------------
MUL_1145|M.ulcerans_Agy99 AMTAGAGAYAGAEAVNASPLQ----AALDVLNAPAQALFGRPLIGDGAGG
MMAR_4186|M.marinum_M ALNAGAQSYVGAEAANATPLQTLEQDALGIINAPTQALVGRPLIGNGANG
MAB_4284c|M.abscessus_ATCC_199 PDGPSILSPSLLSPRDNDFLSHNDTDFASHNPIASGNQVMSPSGNVDSFN
MAV_4827|M.avium_104 AALRDALAARRIDNVMLVSAFLAAAALAQNVGGAMGYERTAVLLVEPDTA
.
TH_3810|M.thermoresistible__bu TPGVYTDRQGEDGEDGTGTG------------------------------
Mflv_5091|M.gilvum_PYR-GCK VTSGVVGGNGEDAVGYGATGAAGAAGAAGAAGAAG--------------A
Mvan_1264|M.vanbaalenii_PYR-1 VTSNVTGGNGADAVGYGATGAAGAAGAAGAAGKAG--------------A
MSMEG_0868|M.smegmatis_MC2_155 GTGGIGGTGGGLFGLLGHSGSTGAAGAAGNGGDGGNGGFGYVLIAGPNVT
Mb1121|M.bovis_AF2122/97 -GPGQDGGPGGLLYGNGGNGGTSTTAG-VAGGNGG---------------
Rv1091|M.tuberculosis_H37Rv -GPGQDGGPGGLLYGNGGNGGTSTTAG-VAGGNGG---------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MUL_1145|M.ulcerans_Agy99 -APGQSGGDGGLLYGNGGNGGNGGVG--QAGGAGG---------------
MMAR_4186|M.marinum_M TAANPNGGDGGLLYGNGGNGFTQTGNNNVAGGNGG---------------
MAB_4284c|M.abscessus_ATCC_199 RGPLLDLSFGDLQFGNRDTTAIGDGAVAVGGSNSG---------------
MAV_4827|M.avium_104 TLAVVETSDGSIPDVYKQQIRAESYG------------------------
TH_3810|M.thermoresistible__bu --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK VGSAGAAGEAGETGTWG--NAGLPGKAGDAGGAG----------------
Mvan_1264|M.vanbaalenii_PYR-1 VGSAGTAGSAGAPGVWG--NAGLPGAAGAAGGAG----------------
MSMEG_0868|M.smegmatis_MC2_155 VGSETRGGTGGAGGTGGQSTAAGPGKGGGGGGGGGGAILIGANGGTVDGH
Mb1121|M.bovis_AF2122/97 --AAGLIGNGGAGGGGG---AGAAGGNGGAGGWLYG--------------
Rv1091|M.tuberculosis_H37Rv --AAGLIGNGGAGGGGG---AGAAGGNGGAGGWLYG--------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MUL_1145|M.ulcerans_Agy99 --AAGLIGNGGSGGIGGPGTTGLAGGAGGSGGWLFG--------------
MMAR_4186|M.marinum_M --NAGLIGNGGAGGGGG---TAFAGGNGGHGGLLYG--------------
MAB_4284c|M.abscessus_ATCC_199 ---PIASGQGSTAVNGDVRDSNIINADHGSN-------------------
MAV_4827|M.avium_104 ----DAAGQLSAMVAGLEKLESLPGGLLLVG-------------------
TH_3810|M.thermoresistible__bu -IGGRGGNGG----------------------------------------
Mflv_5091|M.gilvum_PYR-GCK AVGAAGAAG------TVGTAGATGGTG---------------TGANGGAG
Mvan_1264|M.vanbaalenii_PYR-1 AIGTAGVAG------AAGTAGATGGTG---------------VGGNGGAG
MSMEG_0868|M.smegmatis_MC2_155 AIGGNGGNGGNGSTTAAGGNGGTGGTGRVIAEGTGSTAEGTATGGDGGHS
Mb1121|M.bovis_AF2122/97 -NGGAGGAGGTSVIPGVAGGNGGAGGS----AGLWGTGGAGGDGGNGRSG
Rv1091|M.tuberculosis_H37Rv -NGGAGGAGGTSVIPGVAGGNGGAGGS----AGLWGTGGAGGDGGNGRSG
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MUL_1145|M.ulcerans_Agy99 -NGGTGGRGGI-GTTGIGGIGGTGGDA----VGLFGHGGTGGTGGNGPDI
MMAR_4186|M.marinum_M -NGGAGAIGGD-GTG------------------------------NGFGS
MAB_4284c|M.abscessus_ATCC_199 -VGVDQSQTR----------------------------------------
MAV_4827|M.avium_104 -SGVDVAP------------------------------------------
TH_3810|M.thermoresistible__bu --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK GVGGVGGTGAAG--------------AAGGAGGLGETGTTGGAGGVGGQ-
Mvan_1264|M.vanbaalenii_PYR-1 QAGGIGGTGAAG--------------AAGQAGTAGETGVTGGVGGIGGQ-
MSMEG_0868|M.smegmatis_MC2_155 TGTGIGGNGGIGSVYAYGNNGAVSGTATGGRGGDGIDGGTGGAGGMGEIY
Mb1121|M.bovis_AF2122/97 PVNVAGSAGGNG----------------GAGGAAG-LFGDAGAGGN----
Rv1091|M.tuberculosis_H37Rv PVNVAGSAGGNG----------------GAGGAAG-LFGDAGAGGN----
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MUL_1145|M.ulcerans_Agy99 FI-----AGGAG----------------GSGGTGGLLFGNGGAGGGAPWG
MMAR_4186|M.marinum_M LS-----GGGNG----------------GSGGGAG-LWGVGGAGG-----
MAB_4284c|M.abscessus_ATCC_199 -----------------------------VGGDYTNVSGHGSADIDKSVT
MAV_4827|M.avium_104 ----------------------------LKQVLQTTTFLDVSVAEEPETA
TH_3810|M.thermoresistible__bu -SSSGTHPMAEDGEHVKALD------------------------------
Mflv_5091|M.gilvum_PYR-GCK -GTAGGTGGVGGIGGAGSTGAVGGVGGKG----IQGGQG-----------
Mvan_1264|M.vanbaalenii_PYR-1 -GTEGGTGGVGGVGGVGATGGAGGVGGKG----IQGGQG-----------
MSMEG_0868|M.smegmatis_MC2_155 SGADGEATGISAGGDGGSATGADSLGGRGGTSWVQAGYGPTTGGKASGTA
Mb1121|M.bovis_AF2122/97 GGKGGAGGAAFSINFTAGDGGAGGAGGSGGHALLWG--------------
Rv1091|M.tuberculosis_H37Rv GGKGGAGGAAFSINFTAGDGGAGGAGGSGGHALLWG--------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MUL_1145|M.ulcerans_Agy99 GADGGAGGDARLIGNGGGGGYEGSLGVLSGGTAGPGGDG-----------
MMAR_4186|M.marinum_M --NGGAGGSPTVPGHAGGNGGSGGIGGAGG--------------------
MAB_4284c|M.abscessus_ATCC_199 VVDDHSQRNTTNINDSFNTDRSTNIGSGNTTNTEIGSHN-----------
MAV_4827|M.avium_104 LARGAALAAANAPLFASSTAALAYAQDPGTGAVDQYSLP-----------
TH_3810|M.thermoresistible__bu ----------GRPGLDG----------------------------GNGSH
Mflv_5091|M.gilvum_PYR-GCK --LQGGKGGDGGAGGKGGDADSMGS------------------AGATGGK
Mvan_1264|M.vanbaalenii_PYR-1 --LQGGQGGDGGTGGTGGDATSMGE------------------AGATGGK
MSMEG_0868|M.smegmatis_MC2_155 KAGHGGKASDGGKGGNGGDALVMAAGATGVATGNTAIGGNGGAASANGAV
Mb1121|M.bovis_AF2122/97 ---AGGAGGNGGSGGTG------------------------GAGGSTAGA
Rv1091|M.tuberculosis_H37Rv ---AGGAGGNGGSGGTG------------------------GAGGSTAGA
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MUL_1145|M.ulcerans_Agy99 -GNAVGLIGNGGAGGAG------------------------AAG-LSGVT
MMAR_4186|M.marinum_M ------VFGNGGAGGNG------------------------GIG-GTGGT
MAB_4284c|M.abscessus_ATCC_199 ------QANIGTSTSAG----------------------------GSAAV
MAV_4827|M.avium_104 --DYLYVPVDPEPGDDE---------------------------LAYSAV
TH_3810|M.thermoresistible__bu GGNGGHGGRGGFLG------------------------------------
Mflv_5091|M.gilvum_PYR-GCK GGNGGNGGRGGLFG---------------KGGNAGNGAD-----------
Mvan_1264|M.vanbaalenii_PYR-1 GGNGGNGGRGSLFG---------------RGGNAGNGGN-----------
MSMEG_0868|M.smegmatis_MC2_155 GGNGGFTNIAAIHGSITDSSATSGHGGAAQGGNGGNGGNGWVQAYDPNGP
Mb1121|M.bovis_AF2122/97 GGNGGAGGGGGTGGLLFGNGGAGGHGAAAGNGLAAGNGVS----------
Rv1091|M.tuberculosis_H37Rv GGNGGAGGGGGTGGLLFGNGGAGGHGAAAGNGLAAGNGVS----------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MUL_1145|M.ulcerans_Agy99 GGIGGNGGNGAQLFGNGGAGGAGGQSQLASGGTGGSGGMA----------
MMAR_4186|M.marinum_M GGNGGIGGNG-------AAGGAGG-----LWGDGGVGGNG----------
MAB_4284c|M.abscessus_ATCC_199 GGNAGLAGNAGLAG---------------NAGLAGNAGLAG---------
MAV_4827|M.avium_104 GEEDAESPTVVIEKLFLPEDSEPRRRP-----------------------
TH_3810|M.thermoresistible__bu --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK -----------GGTGGAGGAGGTGG-TGGAGGTGG---------------
Mvan_1264|M.vanbaalenii_PYR-1 -----------GGTGGNGGNGGTGG-TGGNGGTGG---------------
MSMEG_0868|M.smegmatis_MC2_155 AGTTIDKGKAAGGNGGDGGFNGTGGATGGRGGDGAGASVWKANGQHSTGQ
Mb1121|M.bovis_AF2122/97 --------SSGGGGAGGTG---GAGGDGGAGGAGGNAR------------
Rv1091|M.tuberculosis_H37Rv --------SSGGGGAGGTG---GAGGDGGAGGAGGNAR------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MUL_1145|M.ulcerans_Agy99 --------ALFGNGGAGGAAGVSLSGAPGTGGNGGSAQ------------
MMAR_4186|M.marinum_M --------AVGGNSGGG----FGVMNDGGSGGHGGDAR------------
MAB_4284c|M.abscessus_ATCC_199 --------------------NAGLAGNAGLAGNAG---------------
MAV_4827|M.avium_104 --------------------------------------------------
TH_3810|M.thermoresistible__bu --IGGSGGWGGHGGNGGDTDADGGN-------------------------
Mflv_5091|M.gilvum_PYR-GCK --TGGTGGIGGAGSTGGTGGTGGTGGTGGTGGTG-GTGGTGGTG-GTGGK
Mvan_1264|M.vanbaalenii_PYR-1 --TGGTGGIGGAGSTGGTGGTGGTGGTGGTGGTG-GTGGTGGTG-GTGGK
MSMEG_0868|M.smegmatis_MC2_155 TDTGGNGGRGGDGGTFVNAGANGNGGAGGAGGVSEGEGGTGGHG-GDGGR
Mb1121|M.bovis_AF2122/97 --LWGVGGAGGAGGDGGAGGAGGKGGSGLSGNANGGAGGDSGRG-GTGGA
Rv1091|M.tuberculosis_H37Rv --LWGVGGAGGAGGDGGAGGAGGKGGSGLSGNANGGAGGDSGRG-GTGGA
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MUL_1145|M.ulcerans_Agy99 --FMGDGDSGGLGDSGGSAGAAGAGGLIGNPLDVVNAPTEALLGRPLIGD
MMAR_4186|M.marinum_M --LFGNGGNGGAGAVGGAGGNGADGGIGG----------------QFFGN
MAB_4284c|M.abscessus_ATCC_199 --LAGNAGLAGNAGLAGNAGLAGNAGLAGNAG------------------
MAV_4827|M.avium_104 --VLLVGSGLAVVGISAVLALEIALAIG----------------------
TH_3810|M.thermoresistible__bu ----------------GGDGGNGGSAGRGGTGGLRGVFGINGGNGRAGLG
Mflv_5091|M.gilvum_PYR-GCK GGTGGTGGAGGTG----GDGGTGGTGGTGGTG---------GTGGTGGTG
Mvan_1264|M.vanbaalenii_PYR-1 GGTGGTGGDGGTG----GTGGTGGTGGTGGTG---------GTGGTGGTG
MSMEG_0868|M.smegmatis_MC2_155 GGDGALGGNGGTGGVGLGNGGKGGNGGNGGNGGTYVDPSHTGAGGNGGNG
Mb1121|M.bovis_AF2122/97 GGEGGAAGLLVGTGGHGGDGGAGGAAVKGGDGGAAAGTGIAGAGGRGGAG
Rv1091|M.tuberculosis_H37Rv GGEGGAAGLLVGTGGHGGDGGAGGAAVKGGDGGAAAGTGIAGAGGRGGAG
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MUL_1145|M.ulcerans_Agy99 GADGAPGESGQDGGLLYGNGGNGGNGLSGQAGGAGGAAGLIGNGGNGGIG
MMAR_4186|M.marinum_M GGDG-------------GAGGIGTAGLAGSGGTGGSAVGLVGNGGTGGAG
MAB_4284c|M.abscessus_ATCC_199 ---------------LAGNAGLAGNAGLAGNAGLAGNAGLAGNAGLAGNA
MAV_4827|M.avium_104 ----------------IRTTGTVALQPTPNQHLIVPTEQAPAPPPVQASA
TH_3810|M.thermoresistible__bu GRGX-------------------------XXXGGGVGAAVR---------
Mflv_5091|M.gilvum_PYR-GCK GAG-----------DGTGGTGGTGG----TGGQGGQGGQGG---------
Mvan_1264|M.vanbaalenii_PYR-1 GAG-----------DGLGGTGGTGG----TGGFGGQGGQGG---------
MSMEG_0868|M.smegmatis_MC2_155 GAGRIRVNNGTATGTATGGNGGNGGNGDADGHRGGKGGDGGEALIRATVI
Mb1121|M.bovis_AF2122/97 GSG----------GSGGDGGGGAAGPAGWLFGDGGAGGNGG---------
Rv1091|M.tuberculosis_H37Rv GSG----------GSGGDGGGGAAGPAGWLFGDGGAGGNGG---------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MUL_1145|M.ulcerans_Agy99 GPG----------TTGMSGGAGGAG--GWLIGNGGHGGIGG---------
MMAR_4186|M.marinum_M GLG----------PIGGAGGNGGGG--GLIGNGGNGGAGGA---------
MAB_4284c|M.abscessus_ATCC_199 GLAG---------NAGLAGNAGLAG----NAGLAGNAAVAG---------
MAV_4827|M.avium_104 PQPK----------ISVPEPVAAPKPLSPPVAAPLPAAPPP---------
TH_3810|M.thermoresistible__bu --------SGNGVFSGGGGTPSAGFG------------------------
Mflv_5091|M.gilvum_PYR-GCK --------TGGTGGQGG-LGGGGGTG-----------------------G
Mvan_1264|M.vanbaalenii_PYR-1 --------TGGTGGQGG-LGGVGGTG-----------------------G
MSMEG_0868|M.smegmatis_MC2_155 GSNASGTATGGDGGNGGTLGATNGTGGAATIVAYNVVQANPQASGTATDG
Mb1121|M.bovis_AF2122/97 --AAAAGGAGGQAGGGGGNGGNGGNG-----------------------G
Rv1091|M.tuberculosis_H37Rv --AAAAGGAGGQAGGGGGNGGNGGNG-----------------------G
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MUL_1145|M.ulcerans_Agy99 --LGIG--IGDSGGAGGAGGAAIGLF-----------------------G
MMAR_4186|M.marinum_M --ASAT--VGTPAPGVGGNGGAAGLF-----------------------G
MAB_4284c|M.abscessus_ATCC_199 ---------NAAVAGNAAVAGNAAVG-----------------------G
MAV_4827|M.avium_104 --------AAPPLPEAPPIPAAPPVVP-----------------------
TH_3810|M.thermoresistible__bu --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK QGGTGGTGGQGGTGGTGGTGGTG--------GTGGAGGDGGLGGLGGFGG
Mvan_1264|M.vanbaalenii_PYR-1 TGGTGGTGGQGGTGGTGGTGGTG--------GTGGAGGDGGLGGLGGFGG
MSMEG_0868|M.smegmatis_MC2_155 HGGSGINGGHGGNGGQGTIEANGPSAVASGIGAGGNGGDGIDGGLGGNGG
Mb1121|M.bovis_AF2122/97 NGGNGGNGATGGWLYGNGGAGGQGATAGAGGAGANGVSSTNGG---GNGG
Rv1091|M.tuberculosis_H37Rv NGGNGGNGATGGWLYGNGGAGGQGATAGAGGAGANGVSSTNGGGTGGNGG
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MUL_1145|M.ulcerans_Agy99 NGGTGGTGGYNQAFGAVSGVGG------AGGAGGQWYGN------GGDGG
MMAR_4186|M.marinum_M DGGNGGAG-----APGLSGLGG------AGGRGGYLIGS------GGNGG
MAB_4284c|M.abscessus_ATCC_199 VLNTGVSGAIGGSSHVGGAINES---------------------------
MAV_4827|M.avium_104 --VPVVVPPVPVPVPVRIPVPDP---------------------------
TH_3810|M.thermoresistible__bu -----VPTTIQFPAGSCTSRAVSREGIMPSSRAASARAG-----------
Mflv_5091|M.gilvum_PYR-GCK SGGTGGQGGLGGPGGSTGGAGGAGG--QAGTAGKGGLFG----GSGSAGK
Mvan_1264|M.vanbaalenii_PYR-1 VGGTGGQGGQGGPGGSTGGAGGAGG--QAGVAGKGGLFG----GSGSAGT
MSMEG_0868|M.smegmatis_MC2_155 DGVVNTTANAANPGSATGTATGGDGGKATGTASQGGNGGPSWVQSGYGST
Mb1121|M.bovis_AF2122/97 IGGTGGSGGAGGNAGLLGVGGAGGHGASGGAGDRGGAGG-----TGFISS
Rv1091|M.tuberculosis_H37Rv IGGTGGSGGAGGNAGLLGVGGAGGHGASGGAGDRGGAGG-----TGFISS
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MUL_1145|M.ulcerans_Agy99 TSWGGAAAGAGGDAGLIDNGGDGDSAGVLRQNGIGGHGG-----AGGS--
MMAR_4186|M.marinum_M -----AGAGGGDGGYLSGNGGNGGDGVIVGNGSAGGAGG-----NALG--
MAB_4284c|M.abscessus_ATCC_199 ---LGGSGSVGGSTAVGGGAHTGVGGGVSTGVGVGSHVG-----GGISES
MAV_4827|M.avium_104 ----VSPPQLLAPPRLSVPQPVQPPVRVPQPPSPPQVGG------TVPQS
TH_3810|M.thermoresistible__bu --AACASSTSRSRRSFCCSRA-----------------------------
Mflv_5091|M.gilvum_PYR-GCK AGATGAAGASGGKGAQGATGAQGATG------AQGATG-ATGAAGKAGAT
Mvan_1264|M.vanbaalenii_PYR-1 AGVTGASGASGGKGAQGATGAQGATG------AQGATG-ATGASGAQGSA
MSMEG_0868|M.smegmatis_MC2_155 LGGNATGTATAGKGGEASNGGVAGNGGNALVMAAGTTGVATGNTATGGDG
Mb1121|M.bovis_AF2122/97 DGGAGGDGGDGGNGGAGGTGGLLFGAGGNGGPGGSGGAADIGGNGGAGNG
Rv1091|M.tuberculosis_H37Rv DGGAGGDGGDGGNGGAGGTGGLLFGAGGNGGPGGSGGAADIGGNGGAGNG
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MUL_1145|M.ulcerans_Agy99 LFGDGGDGGSAGFQSTAGDGGNAGLVGNGGNGGWAIYNSFAGDDGSGGTA
MMAR_4186|M.marinum_M LFGHGGAGGAGGYDVTTQAGLTG------------------GNGGVGGKL
MAB_4284c|M.abscessus_ATCC_199 LGGSGSVGGSTAVGGGAHTGVGGGVS-------TGVGVGSHVGGGISESL
MAV_4827|M.avium_104 PPQHQTPPGEGTPPKPDGPGNYG-----------GGHVPTPGAGGSGGSG
TH_3810|M.thermoresistible__bu --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK GAAGAAGAAGSAG-----------TTGAQGSAGTNGA-NGANGSQGAAGK
Mvan_1264|M.vanbaalenii_PYR-1 GSAGSAGVAGSAG-----------TTGAQGSAGTNGA-NGANGSQGAAGK
MSMEG_0868|M.smegmatis_MC2_155 GAATTAGATGGAGGFSNIAAIHGAITDSTAISGHGGAGNGGNGGKGADGW
Mb1121|M.bovis_AF2122/97 GGTDGNGGNGGSGGGAG-------SGGDGGGAGGNGAWLFGNGGAGGGGG
Rv1091|M.tuberculosis_H37Rv GGTDGNGGNGGSGGGAG-------SGGDGGGAGGNGAWLFGNGGAGGGGG
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MUL_1145|M.ulcerans_Agy99 IGNGGDGGANIVSSGFI-------LGAGGGGNGGNAVGLIGNGGAGGTGA
MMAR_4186|M.marinum_M IGDGGLGGD--GGIGLA-------GTGGNGGNGGDAVGVIGNGGVGGAG-
MAB_4284c|M.abscessus_ATCC_199 GGSGSVGGSTAVGG------------GAHTGVGGGVNTGVGVGSHVGGGI
MAV_4827|M.avium_104 GGHVPTPGAGGSG-------------GSGGGHVPTPGTGGPGGTGGSGGG
TH_3810|M.thermoresistible__bu --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK AGATGTTGATG--------AAGEDGDAGSGGSG-INGGAGGAGG------
Mvan_1264|M.vanbaalenii_PYR-1 AGATGTTGATG--------AAGDAGDPGSEAVD-INGGAGGAGG------
MSMEG_0868|M.smegmatis_MC2_155 VQAYDPAGPVGSKIANSSAVAGNGGDGGVNGTGGASGGDGGNGGNTSVWK
Mb1121|M.bovis_AF2122/97 KGGNGAGGGLGGGSFGLPGLNGSGGDGGDGGNGAPG-----GVLYGNGGA
Rv1091|M.tuberculosis_H37Rv KGGNGAGGGLGGGSFGLPGLNGSGGDGGDGGNGAPG-----GVLYGNGGA
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MUL_1145|M.ulcerans_Agy99 DGFSTALGSDGGNGGTGAWLLGNGGAGGSGGSTAGVHPAGDGGNSGMSAL
MMAR_4186|M.marinum_M ----------------GVGAFGSGGTGGNGGAGG---------------A
MAB_4284c|M.abscessus_ATCC_199 SESLGGSGSVGGSTAVGGGAHTSAINDALGGSGSVG--------------
MAV_4827|M.avium_104 HVPTPGAGTPGGSGGGHLPFPGAGSTPGGSGGGHLP--------------
TH_3810|M.thermoresistible__bu --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK -----AGGEGGEGGDGGKGGAGAE--------GGAGGGGGAGGSGAGGAG
Mvan_1264|M.vanbaalenii_PYR-1 -----AGGEGGEGGAGGAGGDGSE--------GGAGGSGGAGGSGTGGAG
MSMEG_0868|M.smegmatis_MC2_155 SGGQTADGEHNTGGNGGNGGDGSEPGPGGNGAGGAGGNGGTGGTTAGGSG
Mb1121|M.bovis_AF2122/97 GGQGSSGGIGGPGATGGAGGKGGDGG--DAQLIGDGGNGGNGGAGGTGGT
Rv1091|M.tuberculosis_H37Rv GGQGSSGGIGGPGATGGAGGKGGDGG--DAQLIGDGGNGGNGGAGGTGGT
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MUL_1145|M.ulcerans_Agy99 IGNGGAGGSAGVSPTGVFPSNGGSGG--NAQLIGDGGDGGRGDSGGTG--
MMAR_4186|M.marinum_M VGNGGAGGDAGSSGN-LSPAGGGKGG--NAKLVGNGGDGGAGVFGGLG--
MAB_4284c|M.abscessus_ATCC_199 -GSTAVGGGAHTSAINESMNSSINASHSSSMNESFGSSMGSHGAAGTG--
MAV_4827|M.avium_104 ---TPGAGTPGGGLGGFGGGHAPAPG------GGLGGGGGHAPAPGGG--
TH_3810|M.thermoresistible__bu ----------------------------
Mflv_5091|M.gilvum_PYR-GCK --GAGGSGGSGGSGGSGGSGGAAGDSDD
Mvan_1264|M.vanbaalenii_PYR-1 --GAGGSGGSGGSGGAGGSGGAAGDSD-
MSMEG_0868|M.smegmatis_MC2_155 NGGNGGNGGNGGADGTPGTAGTTGANNP
Mb1121|M.bovis_AF2122/97 PGPGGPGGSGGLGGLLFGQTGTAGVSP-
Rv1091|M.tuberculosis_H37Rv PGPGGPGGSGGLGGLLFGQTGTAGVSP-
MLBr_01183|M.leprae_Br4923 ----------------------------
MUL_1145|M.ulcerans_Agy99 -------GAGGTGGSLAGHDGSDGD---
MMAR_4186|M.marinum_M -------GDGGTGGQLFGNMGLNGPA--
MAB_4284c|M.abscessus_ATCC_199 ---FEAQGHAQGHASETAHTTLPGAEHH
MAV_4827|M.avium_104 ------LGGFGGGHSGGGLGGLGGGHK-