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LSYVMAVPEIIEAAASTAAASQTAQTVAAAEDEVSAAIATVLSSHGQGYQVLSARALEFHTRLAQALSAG AGAYSGAEASSAGLLAAVNEPIAALTGRPLIGNGANGTPGLGTDGAPGGWLIGNDGAGGSGAAGSAGGAG GAAGLIGAGGAGGAGGAGGSSTGGAGGTGGAGGAGEWLFGPGGVGGAGGSSSSAGGAGGVGGAGGLFGGG LGGAGGAGVSASGGAGGAGGAGGALAGFLGAGGSDGGAGGTGVNHEGGAGGAGGAGGLIAGTGGNGGAGG TDAYSRGGAGGAGGTGGTGGTDMSDSGGTGGAGGNAGLLFGSGGAGGAGGAAVALNDVGGAGGAGGNAGL FGNGGVGGVGGVGAGDGGAGGRAGLVIGNGGAGGAGGESFGFGAGVGGAGGNGGNGVLIGNGGNAGTGGT GLSTGSTGAGGISGLLLGLDGFNAPASTSALHNLQQQALGVINEPTQALTGRPLIGNGTPGAAGSGTDGT PGGWLLGDGGAAGLLGTGGTGGAGARLAGGAGGTGGAGGAGGWLLGDGGGGGGGASGGGGGASGGTGGTG GAGGLLSAGGAGGVGGAGGYNTSGPGGNGGSGGNAGTLFGSGGGGNGGSGYSGIGGTGGTGGNAVLLGGG GAGGAGGISFTGAGGQGGAGGTGGQLSGNGGSGGTGGEGDYVGGADSGGAGGAGGNAGLTGDGGNGGSGG TPGSPGGGGTGGALIGQDGLARLAVTGR
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. ulcerans Agy99 | MUL_4280 | - | - | 100% (728) | PE-PGRS family protein |
| M. ulcerans Agy99 | MUL_3062 | - | 0.0 | 54.42% (860) | PE-PGRS family protein |
| M. ulcerans Agy99 | MUL_2485 | - | 0.0 | 58.47% (720) | PE-PGRS family protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0286c | PE_PGRS3 | 0.0 | 52.18% (893) | PE-PGRS family protein |
| M. gilvum PYR-GCK | Mflv_5091 | - | 1e-129 | 45.55% (674) | triple helix repeat-containing collagen |
| M. tuberculosis H37Rv | Rv0746 | PE_PGRS9 | 0.0 | 55.50% (827) | PE-PGRS family protein |
| M. leprae Br4923 | MLBr_01556 | infB | 4e-10 | 27.06% (255) | translation initiation factor IF-2 |
| M. abscessus ATCC 19977 | MAB_4284c | - | 5e-46 | 31.82% (550) | hypothetical protein MAB_4284c |
| M. marinum M | MMAR_5207 | - | 0.0 | 83.20% (845) | PE-PGRS family protein, PE_PGRS9_2 |
| M. avium 104 | MAV_4827 | - | 5e-25 | 45.57% (158) | hypothetical protein MAV_4827 |
| M. smegmatis MC2 155 | MSMEG_0868 | - | 1e-100 | 37.04% (837) | hypothetical protein MSMEG_0868 |
| M. thermoresistible (build 8) | TH_3810 | - | 1e-38 | 38.46% (299) | PUTATIVE - |
| M. vanbaalenii PYR-1 | Mvan_1264 | - | 1e-124 | 43.23% (724) | triple helix repeat-containing collagen |
CLUSTAL 2.0.9 multiple sequence alignment
MUL_4280|M.ulcerans_Agy99 --------------------------------------------------
MMAR_5207|M.marinum_M --------------------------------------------------
Rv0746|M.tuberculosis_H37Rv --------------------------------------------------
Mb0286c|M.bovis_AF2122/97 --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_1264|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_0868|M.smegmatis_MC2_155 MHERLRERAGGVRKTLSDFAEGAGLKPSDTDDTRSPLRKPKFPAALAPES
TH_3810|M.thermoresistible__bu --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 --------------------------------------------------
MAV_4827|M.avium_104 --------------------------------------------------
MLBr_01556|M.leprae_Br4923 --------------------------------------------------
MUL_4280|M.ulcerans_Agy99 --------------------------------------------------
MMAR_5207|M.marinum_M --------------------------------------------------
Rv0746|M.tuberculosis_H37Rv --------------------------------------------------
Mb0286c|M.bovis_AF2122/97 --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_1264|M.vanbaalenii_PYR-1 -------------------MMFLAPPGGPGPISAAIQLTSTGSEATEP--
MSMEG_0868|M.smegmatis_MC2_155 PLPDLKPRWERPTTAPDSETPSITQPQGRDTAADPAEQQATSTNTTDQPT
TH_3810|M.thermoresistible__bu --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 --------------------------------------------------
MAV_4827|M.avium_104 --------------------------------------------------
MLBr_01556|M.leprae_Br4923 --------------------------------------------------
MUL_4280|M.ulcerans_Agy99 ------------------------------------MSYVMAVPEIIEAA
MMAR_5207|M.marinum_M ------------------------------------MSYVMAVPEIIEAA
Rv0746|M.tuberculosis_H37Rv ------------------------------------MSFVLAMPEVLGSA
Mb0286c|M.bovis_AF2122/97 ------------------------------------MSFVIAAPEVIAAA
Mflv_5091|M.gilvum_PYR-GCK --------------------------------------MVTFGGGATPTP
Mvan_1264|M.vanbaalenii_PYR-1 ------------------------------------WYVVSFGGSGAPTP
MSMEG_0868|M.smegmatis_MC2_155 SDSLGAQPTAQVARQVQAPATDPAPAAPSLRPISGLLSVVTLGTTLIPNA
TH_3810|M.thermoresistible__bu --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 ------------------------------------MSIIDFILNLFRDP
MAV_4827|M.avium_104 ---------------------------------MNIVLGVSMAPSSIQMV
MLBr_01556|M.leprae_Br4923 ---------------------------------MAGKARVHELAKELGVT
MUL_4280|M.ulcerans_Agy99 AS-----------------------------------------TAAASQT
MMAR_5207|M.marinum_M AAD----------------------------------------LAAASQT
Rv0746|M.tuberculosis_H37Rv ATDLAALGSVLG----------------------------AADAAAAATT
Mb0286c|M.bovis_AF2122/97 ATDLASLGSSIS----------------------------AANAAAAANT
Mflv_5091|M.gilvum_PYR-GCK ----------------------------------------TSLGAAAVDL
Mvan_1264|M.vanbaalenii_PYR-1 ----------------------------------------NNLAASLVDL
MSMEG_0868|M.smegmatis_MC2_155 PTEPADMPGVWAVMAWARRQPMYSDPAMRTTVNPQAQLPVPTVASAVLDP
TH_3810|M.thermoresistible__bu --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 VEAAS----------------------------------YVADPEAALAN
MAV_4827|M.avium_104 VLEGEYADG-------------------------------ATVEEDAIDV
MLBr_01556|M.leprae_Br4923 SKEVLARLNEQG--------------------------EFVKSASSTVEA
MUL_4280|M.ulcerans_Agy99 AQ--------------------------------------TVAAAEDEVS
MMAR_5207|M.marinum_M TQ--------------------------------------IVAAAEDEVS
Rv0746|M.tuberculosis_H37Rv TG--------------------------------------IVAAAQDEVS
Mb0286c|M.bovis_AF2122/97 TA--------------------------------------LMAAGADEVS
Mflv_5091|M.gilvum_PYR-GCK S------------------------GTSCG----------LICNGQDGTG
Mvan_1264|M.vanbaalenii_PYR-1 S------------------------GTSCG----------LICNGQDGTG
MSMEG_0868|M.smegmatis_MC2_155 TQIVNWLIYQPLHAAGQQFWVVSPIGSTLGGVINTISGQYLIGNGINGTA
TH_3810|M.thermoresistible__bu --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 AG--------------------------------------LSAVSAAQVG
MAV_4827|M.avium_104 TG--------------------------------------ADDAATASAP
MLBr_01556|M.leprae_Br4923 P---------------------------------------VARRLRESFG
MUL_4280|M.ulcerans_Agy99 AA-----IATVLSSHGQGYQVLSARALEFHTRLAQALSAGAGAYSGAEAS
MMAR_5207|M.marinum_M AA-----IATVLSSHGQGYQVLSARALEFHTRLAQALSAGAGAYSGAEAS
Rv0746|M.tuberculosis_H37Rv AA-----IAALFSAHGRAYQVASAQAAAVHAQFVEALSAGAGAYASAEAA
Mb0286c|M.bovis_AF2122/97 TA-----IAALFGAHGQAYQALSAQAQAFHAQFVQALTSGGGAYAAAEAA
Mflv_5091|M.gilvum_PYR-GCK QN-----GGILFGNGGSGWNSDVVGMDGGNGGNGGLFGGNGGNGGNGLGG
Mvan_1264|M.vanbaalenii_PYR-1 QN-----GGILFGNGGSGWNSEIAGVSGGNGGNAGLFGGNGGNGGNGLGS
MSMEG_0868|M.smegmatis_MC2_155 DNPNGGTGGLLFGDGGHGYDGSAAGLAGGNGGNAGLFG-NGGNGGVGWAG
TH_3810|M.thermoresistible__bu --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 AVMP---VVAESVASNYGYQSQWVNTGNPIHDLSGNLQNYYAAQPDGPSI
MAV_4827|M.avium_104 DRVISAILGTREGAADAGLQLSSIGVTWTDQLEAAALRDALAARRIDNVM
MLBr_01556|M.leprae_Br4923 GIKPAADKGAEQVATKAQAKRLGESLDQTLDRALDKAVAGNGATTAAPVQ
MUL_4280|M.ulcerans_Agy99 SAG------------LLAAVNEPIAALTGRP----LIG------NGANGT
MMAR_5207|M.marinum_M SAG------------LLAAVNEPIAALTGRP----LIG------NGANGT
Rv0746|M.tuberculosis_H37Rv GAAVLANPAQSVQQDLLAAVNAQSVALTGRP----LIG------NGANGA
Mb0286c|M.bovis_AF2122/97 AVSP-----------LLDPINEFFLANTGRP----LIG------NGANGA
Mflv_5091|M.gilvum_PYR-GCK GNGG--NGGNAGAFALFGNGGNGGNGGVGVVGATGAVG--APGVAGATGA
Mvan_1264|M.vanbaalenii_PYR-1 GDGG--NGGDAGLFSLFGRGGNGGNGGVGIAGATGAVG--APGVAGATGA
MSMEG_0868|M.smegmatis_MC2_155 LDGG--NGGSGG--LLMGIGGAGGAGGVGADGTSAHVDGGTGGTGGTGGG
TH_3810|M.thermoresistible__bu --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 LSPS-----------LLSPRDNDFLSHNDTD--------------FASHN
MAV_4827|M.avium_104 LVSA-----------FLAAAALAQNVGGAMG----------------YER
MLBr_01556|M.leprae_Br4923 VDHSAAVVPIVAGEGPSTAHREELAPPAGQPSEQPGVP--------LPGQ
MUL_4280|M.ulcerans_Agy99 PG--LGTDGAPGGWLIGNDGAGGSGAAGS---AGGAG-------------
MMAR_5207|M.marinum_M PG--LGTDGAPGGWLIGNGGAGGSGAAGS---AGGAG-------------
Rv0746|M.tuberculosis_H37Rv PG--TGANGAPGGWLLGNGGAGGSAAAGSGL-PGGAG-------------
Mb0286c|M.bovis_AF2122/97 PG--TGANGGDGGWLIGNGGAGGSGAAGVNGGAGGNG-------------
Mflv_5091|M.gilvum_PYR-GCK TGVTSGVVGGNGEDAVGYGATGAAGAAGAAGAAGAAG-------------
Mvan_1264|M.vanbaalenii_PYR-1 TGVTSNVTGGNGADAVGYGATGAAGAAGAAGAAGKAG-------------
MSMEG_0868|M.smegmatis_MC2_155 TGGTGGIGGTGGGLFGLLGHSGSTGAAGAAGNGGDGGNGGFGYVLIAGPN
TH_3810|M.thermoresistible__bu --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 PIASGNQVMSPSGNVDSFNRGPLLDLSFGDLQFGNRD-------------
MAV_4827|M.avium_104 TAVLLVEPDTATLAVVETSDGSIPDVYKQQIRAESYG-------------
MLBr_01556|M.leprae_Br4923 QGTPAAPHPGHPGMPTGPHPGPAPKPGGRPPRVGNNP-----------FS
MUL_4280|M.ulcerans_Agy99 ---GAAGLIGAGGAGGAGGAGGSSTGGAGGTGGAGGAGEWLFG-------
MMAR_5207|M.marinum_M ---GAAGLIGAG---GAGGAGGSSTGGAGGTGGAGGAGGWLFG-------
Rv0746|M.tuberculosis_H37Rv ---GAAGLFGTG---GAGGAGGSSTVGDGEAGGAGGSGGWLLG-------
Mb0286c|M.bovis_AF2122/97 ---GAGGLIGNG---GAGGAGGVASSGIGGSGGAGG-NAMLFG-------
Mflv_5091|M.gilvum_PYR-GCK -AVGSAGAAGEAGETGTWG--NAGLPGKAGDAGGAG--------------
Mvan_1264|M.vanbaalenii_PYR-1 -AVGSAGTAGSAGAPGVWG--NAGLPGAAGAAGGAG--------------
MSMEG_0868|M.smegmatis_MC2_155 VTVGSETRGGTGGAGGTGGQSTAAGPGKGGGGGGGGGGAILIGANGGTVD
TH_3810|M.thermoresistible__bu ------------------------VDGDGGSGGRTG--------------
MAB_4284c|M.abscessus_ATCC_199 -----TTAIGDGAVAVGGSNSGPIASGQGSTAVNGDVR------------
MAV_4827|M.avium_104 ---------------DAAGQLSAMVAGLEKLESLPG--------------
MLBr_01556|M.leprae_Br4923 SAQSVARPIPRPPAPRPSASPSSMSPRPGGAVGGGGPRPPRTG-------
.
MUL_4280|M.ulcerans_Agy99 ---PGGVGGAGG-------------SSSSAGGAGGVG-------------
MMAR_5207|M.marinum_M ---PGGVGGAGG-------------SSSSAGGAGGVG-------------
Rv0746|M.tuberculosis_H37Rv ---TGGVGGVGG-------------LGAGAGGAGGVG-------------
Mb0286c|M.bovis_AF2122/97 ---AGGAGGAGGGVVALTGGAGGFTNGSALGGAGGAG-------------
Mflv_5091|M.gilvum_PYR-GCK --AVGAAGAAG--------------TVGTAGATGGTG-------------
Mvan_1264|M.vanbaalenii_PYR-1 --AIGTAGVAG--------------AAGTAGATGGTG-------------
MSMEG_0868|M.smegmatis_MC2_155 GHAIGGNGGNGGN--------GSTTAAGGNGGTGGTGRVIAEGTGSTAEG
TH_3810|M.thermoresistible__bu -----------------------LFSKLSRGGDGGDG-------------
MAB_4284c|M.abscessus_ATCC_199 -------------------------DSNIINADHGSN-------------
MAV_4827|M.avium_104 -------------------------GLLLVGSGVDVAP------------
MLBr_01556|M.leprae_Br4923 ----VPRPGGGR-------------PGAPVGGRSDAG-------------
.. .
MUL_4280|M.ulcerans_Agy99 ----GAGGLFGGG-LGGAGGAGV------------SASGGAGG------A
MMAR_5207|M.marinum_M ----GAGGLFGGGGLGGAGGAGV------------SASGGAGG------A
Rv0746|M.tuberculosis_H37Rv ----GAGGLLGAGGHGGAGGLG-------------AVTGGVGG------T
Mb0286c|M.bovis_AF2122/97 ----GAGGLFATGGVGGSGGAG--------------SSGGAGG------A
Mflv_5091|M.gilvum_PYR-GCK --TGANGGAGGVGGVGGTGAAG--------------AAGGAGGLGETGTT
Mvan_1264|M.vanbaalenii_PYR-1 --VGGNGGAGQAGGIGGTGAAG--------------AAGQAGTAGETGVT
MSMEG_0868|M.smegmatis_MC2_155 TATGGDGGHSTGTGIGGNGGIGSVYAYGNNGAVSGTATGGRGGDGIDGGT
TH_3810|M.thermoresistible__bu -------------GLGGNGGHG-----------------GGTG-------
MAB_4284c|M.abscessus_ATCC_199 -----VGVDQSQTRVGGDYTNVS----------------GHGS-------
MAV_4827|M.avium_104 ----LKQVLQTTTFLDVSVAEEP---------------------------
MLBr_01556|M.leprae_Br4923 ------GGNYRGGGVGALPGGGS---------------GGFRGR----PG
.
MUL_4280|M.ulcerans_Agy99 GGAGGALAGFLGAGGSDGGAGGTG-VNHEGGAGGAGGAGGLIAGTGGNGG
MMAR_5207|M.marinum_M GGAGGALAGFLGAGGGDGGAGGSG-VNHEGGAGGAGGAGGLIAGTGGNGG
Rv0746|M.tuberculosis_H37Rv GGAGGLLAGLLAGPGGAGGTGGRG-FLNNGGVGGAGGNAGLLFGAGG---
Mb0286c|M.bovis_AF2122/97 GGAGGLFG-----AGGTGGHGGFA-DSSFGGVGGAGGAGG-LFGAGGEGG
Mflv_5091|M.gilvum_PYR-GCK GGAGGVGGQ--GTAGGTGGVGGIGGAGSTGAVGGVGGKG----IQGGQG-
Mvan_1264|M.vanbaalenii_PYR-1 GGVGGIGGQ--GTEGGTGGVGGVGGVGATGGAGGVGGKG----IQGGQG-
MSMEG_0868|M.smegmatis_MC2_155 GGAGGMGEIYSGADGEATGISAGGDGGSATGADSLGGRGGTSWVQAGYGP
TH_3810|M.thermoresistible__bu -------------------------IISLLSLAGNGGNG-----------
MAB_4284c|M.abscessus_ATCC_199 --ADIDKSVTVVDDHSQRNTTNINDSFNTDRSTNIGSGNTTNTEIGSHN-
MAV_4827|M.avium_104 --ETALARGAALAAANAPLFASSTAALAYAQDPGTGAVDQYSLPDYLYVP
MLBr_01556|M.leprae_Br4923 GGGHGGGGRPGQRGGAAGAFGRPGGAPRRGRKSKRQKRQEYDSMQAPVVG
MUL_4280|M.ulcerans_Agy99 AGGTDAYSRGGAGGAG-------------GTGGTGGTD------------
MMAR_5207|M.marinum_M AGGTDAYSRGGAGGAGGDAGLLFGSGGAGGTGGTGGTD------------
Rv0746|M.tuberculosis_H37Rv ------------------------------TGGSGGAG------------
Mb0286c|M.bovis_AF2122/97 SGGHSLVAGGDGGAGGNAG--MLALGAAGGAGGIGGDGG-----------
Mflv_5091|M.gilvum_PYR-GCK ------------LQGGKGG--------DGGAGGKGGDADSMGS-------
Mvan_1264|M.vanbaalenii_PYR-1 ------------LQGGQGG--------DGGTGGTGGDATSMGE-------
MSMEG_0868|M.smegmatis_MC2_155 TTGGKASGTAKAGHGGKAS--------DGGKGGNGGDALVMAAGATGVAT
TH_3810|M.thermoresistible__bu -----------------------------GNGYRTTDN------------
MAB_4284c|M.abscessus_ATCC_199 ------------------------------QANIGTSTS-----------
MAV_4827|M.avium_104 -----------------------------VDPEPGDDE------------
MLBr_01556|M.leprae_Br4923 G--------------------------VRLPHGNGETIRLARG-------
MUL_4280|M.ulcerans_Agy99 -----------MSDSGGTGGAGGNAG--LLFG---------------SGG
MMAR_5207|M.marinum_M -----------MSDSGGTGGAGGNAG--LLFG---------------SGG
Rv0746|M.tuberculosis_H37Rv -----------LGGDGGAGGAGGNTG--VLFG---------------NAG
Mb0286c|M.bovis_AF2122/97 --------TLTAGGIGGAGGAGGNAG--LLFG---------------SGG
Mflv_5091|M.gilvum_PYR-GCK -----------AGATGGKGGNGGNGGRGGLFG---------------KGG
Mvan_1264|M.vanbaalenii_PYR-1 -----------AGATGGKGGNGGNGGRGSLFG---------------RGG
MSMEG_0868|M.smegmatis_MC2_155 GNTAIGGNGGAASANGAVGGNGGFTNIAAIHGSITDSSATSGHGGAAQGG
TH_3810|M.thermoresistible__bu -----------NALDGGHGGNGGNVGFFSLFN---------------LGG
MAB_4284c|M.abscessus_ATCC_199 -----------AGGSAAVGGNAGLAGNAGLAG---------------NAG
MAV_4827|M.avium_104 ---------LAYSAVGEEDAESPTVVIEKLFLP--------------EDS
MLBr_01556|M.leprae_Br4923 ---------ASLSDFAEKIDANPAALVQALFNLG---------EMVTATQ
. . :
MUL_4280|M.ulcerans_Agy99 AGGAGGAAV------------------ALNDVGGAGGAGGNAG-LFGNGG
MMAR_5207|M.marinum_M AGGAGGAAV------------------ALNDVGGAGGAGGNAG-LFGNGG
Rv0746|M.tuberculosis_H37Rv SGGTGGFG---------------------DTDGGAGGAGGDAG-WLGSGG
Mb0286c|M.bovis_AF2122/97 SGGAGGFG---------------------FADGGQGGPGGNAGTVFGSGG
Mflv_5091|M.gilvum_PYR-GCK NAGNGAD----------------------GGTGGAGGAGGTGG-TGGAGG
Mvan_1264|M.vanbaalenii_PYR-1 NAGNGGN----------------------GGTGGNGGNGGTGG-TGGNGG
MSMEG_0868|M.smegmatis_MC2_155 NGGNGGNGWVQAYDPNGPAGTTIDKGKAAGGNGGDGGFNGTGGATGGRGG
TH_3810|M.thermoresistible__bu AGGWGGS--------------------------GVDGVDVVGG-------
MAB_4284c|M.abscessus_ATCC_199 LAGNAGLAG-------------------NAGLAGNAGLAGNAG-LAGNAG
MAV_4827|M.avium_104 EPRRRPVLLVG---------------------SGLAVVGISAVLALEIAL
MLBr_01556|M.leprae_Br4923 SVGDETLELLG----SEMNYNVQVVSPEDEDRELLEPFDLTYGEDQGDED
MUL_4280|M.ulcerans_Agy99 VGG-----------------VGGVG-AGDG---GAGGRAGLVIGNGGAGG
MMAR_5207|M.marinum_M VGG-----------------VGGVG-AGDG---GAGGRAGLVIGNGGAGG
Rv0746|M.tuberculosis_H37Rv VGG-----------------AGGFGETGDGGVGGAGGKAGLLIGNGGAGG
Mb0286c|M.bovis_AF2122/97 AGG-----------------NGGVGQGFAGGIGGAGGTPG-LIGNGGNGG
Mflv_5091|M.gilvum_PYR-GCK TGG-----------------TGGTG--GIGGAGSTGGTGG-TGGTGGTGG
Mvan_1264|M.vanbaalenii_PYR-1 TGG-----------------TGGTG--GIGGAGSTGGTGG-TGGTGGTGG
MSMEG_0868|M.smegmatis_MC2_155 DGAGASVWKANGQHSTGQTDTGGNG--GRGGDGGTFVNAG-ANGNGGAGG
TH_3810|M.thermoresistible__bu ------------------------------------------NPDGGTPG
MAB_4284c|M.abscessus_ATCC_199 LAG-------------------------NAGLAGNAGLAGNAGLAGNAGL
MAV_4827|M.avium_104 AIG-----------------------------IRTTGTVALQPTPNQHLI
MLBr_01556|M.leprae_Br4923 ELQVR---------------PPVVTVMGHVDHGKTRLLDTIRKANVREAE
MUL_4280|M.ulcerans_Agy99 AGGESFGFGAGVGGAGGNGGNGVLIGNGGNAGTG----GTGLSTGSTGAG
MMAR_5207|M.marinum_M AGGESFGFGAGVGGAGGNGGNGVLIGNGGNAGTG----GTGLSTGSTGAG
Rv0746|M.tuberculosis_H37Rv AGGQ----GAVTGGTGGAGGDGVLIGNGGNAGIG----GTGPTAGDTGAG
Mb0286c|M.bovis_AF2122/97 NGGAS----AVTGGNGGIGGTGVLIGNGGNGGSG----GIG--AGKAGVG
Mflv_5091|M.gilvum_PYR-GCK TGGTG--GTGGTGGTGGTGGKGGTGGTGGAGGTG----GDGGTGGTGGTG
Mvan_1264|M.vanbaalenii_PYR-1 TGGTG--GTGGTGGTGGTGGKGGTGGTGGDGGTG----GTGGTGGTGGTG
MSMEG_0868|M.smegmatis_MC2_155 AGGVSE-GEGGTGGHGGDGGRGGDGALGGNGGTGGVGLGNGGKGGNGGNG
TH_3810|M.thermoresistible__bu AHGESHTPGVYTDRQGEDGEDGTGTGIGGRGGNG---------GSSSGTH
MAB_4284c|M.abscessus_ATCC_199 AGNAGLAGNAGLAGNAGLAGNAGLAGNAGLAGNAG-------LAGNAGLA
MAV_4827|M.avium_104 VPTEQAPAPPPVQASAPQPKISVPEPVAAPKPLSPPVAAPLPAAPPPAAP
MLBr_01556|M.leprae_Br4923 AGGITQHIGAYQVGVDLDGSERLITFIDTPGHEAFTAMRARGAKATDIAI
.
MUL_4280|M.ulcerans_Agy99 GISG-----LLLGLDGFNAPASTSALHNLQQQALGVINEPTQALTG----
MMAR_5207|M.marinum_M GISG-----LLLGLDGFNAPASTSALHNLQQQALGVINEPTQALTG----
Rv0746|M.tuberculosis_H37Rv GISG-----LLLGADGFNTPASASPLHTLKQQALAAINAPTQTLTG----
Mb0286c|M.bovis_AF2122/97 GVSG-----LLLGLDGFNAPASTSPLHTLQQNVLNVVNEPFQTLTG----
Mflv_5091|M.gilvum_PYR-GCK GTG---------GTGGTGGTGGAG-----------DGTGGTGGTGG----
Mvan_1264|M.vanbaalenii_PYR-1 GTG---------GTGGTGGTGGAG-----------DGLGGTGGTGG----
MSMEG_0868|M.smegmatis_MC2_155 GNGGTYVDPSHTGAGGNGGNGGAGRIRVNNGTATGTATGGNGGNGGNGDA
TH_3810|M.thermoresistible__bu PMAE----------DGEHVKALDG----------------RPGLDG----
MAB_4284c|M.abscessus_ATCC_199 GNAG------LAGNAGLAGNAAVAG---------------NAAVAG----
MAV_4827|M.avium_104 PLPEAPPIPAAPPVVPVPVVVPPVPVPVPVRIPVPDPVSPPQLLAP----
MLBr_01556|M.leprae_Br4923 LVVAADDGVMPQTVEAINHAQAADVPIVVAVNKIDKEGADPAKIRGQLTE
MUL_4280|M.ulcerans_Agy99 -RPLIGNGTPGAAG---------------SGTDGTPGGWLLGDG------
MMAR_5207|M.marinum_M -RPLIGNGTPGAAG---------------SGTDGTPGGWLLGDGGAGGSG
Rv0746|M.tuberculosis_H37Rv -RPLIGNGTPGAVG---------------SGATGAPGGWLLGDGGAGGSG
Mb0286c|M.bovis_AF2122/97 -RPLIGNGANGTPG---------------TGADGGAGGWLFGNGGNGGSG
Mflv_5091|M.gilvum_PYR-GCK TGGQGGQGGQGG-----------------TGGTGGQGG-LGGGGGTG---
Mvan_1264|M.vanbaalenii_PYR-1 TGGFGGQGGQGG-----------------TGGTGGQGG-LGGVGGTG---
MSMEG_0868|M.smegmatis_MC2_155 DGHRGGKGGDGGEALIRATVIGSNASGTATGGDGGNGGTLGATNGTGGAA
TH_3810|M.thermoresistible__bu -----GNGSHGG-----------------NGGHGGRGGFLGIGG------
MAB_4284c|M.abscessus_ATCC_199 NAAVAGNAAVGGVLN--------------TGVSGAIGGSSHVGGAIN---
MAV_4827|M.avium_104 PRLSVPQPVQPPVRVPQ------------PPSPPQVGGTVPQSPPQHQTP
MLBr_01556|M.leprae_Br4923 YGLVAEDFGGDTMFIDISAKVG-------TNIEALLEAVLLTADAALDLR
. .
MUL_4280|M.ulcerans_Agy99 ----------------------------GAAG--LLGTGGTGGAGARL--
MMAR_5207|M.marinum_M -----------------AANTGASGGAGGAAG--LLGTGGTGGAGARL--
Rv0746|M.tuberculosis_H37Rv -----------------AAGSGAPGGAGGAAG--LWGTGGAGGAGGSS--
Mb0286c|M.bovis_AF2122/97 -----------------ATGTNGGDGGDGGAGGIFFGTGGTGGAGGVG--
Mflv_5091|M.gilvum_PYR-GCK --------------------GQGGTGGTGGQG----GTGGTGGTGGTG--
Mvan_1264|M.vanbaalenii_PYR-1 --------------------GTGGTGGTGGQG----GTGGTGGTGGTG--
MSMEG_0868|M.smegmatis_MC2_155 TIVAYNVVQANPQASGTATDGHGGSGINGGHG----GNGGQGTIEANGPS
TH_3810|M.thermoresistible__bu ---------------------------SGGWG----GHGGNGGDTDAD--
MAB_4284c|M.abscessus_ATCC_199 ----------------------------ESLG----GSGSVGGSTAVG--
MAV_4827|M.avium_104 --------------------------PGEGTPPKPDGPGNYGGGHVPT--
MLBr_01556|M.leprae_Br4923 -----------------------ANSGMEAQGVAIEAHLDRGRGPVATVL
. . . *
MUL_4280|M.ulcerans_Agy99 ----AGGAGGTGGAGGAGGWLLGDGGGGGGG-------------------
MMAR_5207|M.marinum_M ----AGGAGGTGGAGGAGGWLLGDGGGGGGG-------------------
Rv0746|M.tuberculosis_H37Rv ----AGG-GGAGGAGGAGGWLLGDGGAGG---------------------
Mb0286c|M.bovis_AF2122/97 ----TTGTGGDGGAGGAA-FLVGSGGNGGSGGAGLTAGGDGGDGGNAGSF
Mflv_5091|M.gilvum_PYR-GCK ------GTGGAGGDGGLG-GLGGFGGSGGTG-------------------
Mvan_1264|M.vanbaalenii_PYR-1 ------GTGGAGGDGGLG-GLGGFGGVGGTG-------------------
MSMEG_0868|M.smegmatis_MC2_155 AVASGIGAGGNGGDGIDG-GLGGNGGDGVVN-------------------
TH_3810|M.thermoresistible__bu --------GGNGGDGGNG----GSAGRGGTG-------------------
MAB_4284c|M.abscessus_ATCC_199 ----GGAHTGVGGGVSTGVGVGSHVGGGISES------------------
MAV_4827|M.avium_104 --------PGAGGSGGSGGGHVPTPGAGGSG-------------------
MLBr_01556|M.leprae_Br4923 VQRGTLRIGDSVVAGDAYGRVRRMVDEHGVD-------------------
. .
MUL_4280|M.ulcerans_Agy99 ------ASGGGGGASGGTGGTGGAGGLLSAGGAGGVG-------------
MMAR_5207|M.marinum_M ------GSGGGGGASGGTGGTGGAGGLLSAGGAGGVGGAGFN--DGGDGG
Rv0746|M.tuberculosis_H37Rv -------IGGASTVLGGTGGGGGVGGLWGAGGAGGAGGTGLVGGDGGAGG
Mb0286c|M.bovis_AF2122/97 FGAAGTGGAGASTKAGGTGGTGGNGGLFANGGAGGSGGLG---GDAGTGG
Mflv_5091|M.gilvum_PYR-GCK ------GQGGLGGPGGSTGGAGGAGG--QAGTAGKGGLFG----GSGSAG
Mvan_1264|M.vanbaalenii_PYR-1 ------GQGGQGGPGGSTGGAGGAGG--QAGVAGKGGLFG----GSGSAG
MSMEG_0868|M.smegmatis_MC2_155 ------TTANAANPGSATGTATGGDGGKATGTASQGGNGGPSWVQSGYGS
TH_3810|M.thermoresistible__bu ------GLRGVFGINGGNGRAG-------LGGRGXXXX------------
MAB_4284c|M.abscessus_ATCC_199 -------LGGSGSVGGSTAVGGGAHTGVGGGVSTGVGVGS----------
MAV_4827|M.avium_104 ------GSGGGHVPTPGTGGPGGTGGSGGGHVPTPGAGTP----------
MLBr_01556|M.leprae_Br4923 --IEAALPSSPVQVIGFTSVPGAGDNFLVVDEDRIARQIADRRSARKRNA
. ..
MUL_4280|M.ulcerans_Agy99 -------------------------------------------------G
MMAR_5207|M.marinum_M AGGSGGLLGGLVGAGGGAGGNGGAGFGGTPGNGGAGGDAGLLGGPGGTGG
Rv0746|M.tuberculosis_H37Rv AGGTGGLLAGLIGAGGG------------------------------HGG
Mb0286c|M.bovis_AF2122/97 AGGNGGLFGAGGTGGAGGSLGPGAG---------GAGGNGGLFGAGGTGG
Mflv_5091|M.gilvum_PYR-GCK KAGATGAAGASGGKGAQGATGAQGATG-------AQGATG-ATGAAGKAG
Mvan_1264|M.vanbaalenii_PYR-1 TAGVTGASGASGGKGAQGATGAQGATG-------AQGATG-ATGASGAQG
MSMEG_0868|M.smegmatis_MC2_155 TLGGNATGTATAGKGGEASNGGVAGNGGNA-LVMAAGTTGVATGNTATGG
TH_3810|M.thermoresistible__bu ------------------------------------------------GG
MAB_4284c|M.abscessus_ATCC_199 ------------------------------------------------HV
MAV_4827|M.avium_104 ------------------------------------------------GG
MLBr_01556|M.leprae_Br4923 LAARSRKRISLEDLDSALKETSQLN--------------------LILKG
MUL_4280|M.ulcerans_Agy99 AGGYNTSG--PGGNG-------------GSGGNAG--TLFGSGGGG-NGG
MMAR_5207|M.marinum_M AGGYNTSG--PGGNG-------------GSGGNAG--TLFGSGGGGGNGG
Rv0746|M.tuberculosis_H37Rv TGGLSTNG--DGGVG-------------GAGGNAG--MLAGPGGAGGAGG
Mb0286c|M.bovis_AF2122/97 SGGHGTPAAVPGGAG-------------GAGGNAGLFSLGASGGAGGSGG
Mflv_5091|M.gilvum_PYR-GCK ATGAAGAAGAAGSAG-----------TTGAQGSAG-TNGA-NGANGSQGA
Mvan_1264|M.vanbaalenii_PYR-1 SAGSAGSAGVAGSAG-----------TTGAQGSAG-TNGA-NGANGSQGA
MSMEG_0868|M.smegmatis_MC2_155 DGGAATTAGATGGAGGFSNIAAIHGAITDSTAISG-HGGAGNGGNGGKGA
TH_3810|M.thermoresistible__bu GVG--------------------------AAVRSG---NGVFSGGGGTPS
MAB_4284c|M.abscessus_ATCC_199 GGGISESLGGSGSVG-------------GSTAVGGGAHTGVGGGVNTGVG
MAV_4827|M.avium_104 SGGGHLPFP-------------------GAGSTPG------GSGGGHLPT
MLBr_01556|M.leprae_Br4923 DNAGTVEALEEALMG--------------IQVDDEVALRVIDRGVGGITE
. . .
MUL_4280|M.ulcerans_Agy99 SG-YSGIGGTGGTG-----------------------------GNAVLLG
MMAR_5207|M.marinum_M SG-YSGIGGTGGTGGSAGLVFSDAGAGGFGGFGSTAGGTGGTGGNAVLLG
Rv0746|M.tuberculosis_H37Rv DGENLDTGGDGGAGG----------------------------SAGLLFG
Mb0286c|M.bovis_AF2122/97 SS-LTDSGGIGGVGG----------------------------AGGLLFG
Mflv_5091|M.gilvum_PYR-GCK AGKAGATGTTGATG---------------------------------AAG
Mvan_1264|M.vanbaalenii_PYR-1 AGKAGATGTTGATG---------------------------------AAG
MSMEG_0868|M.smegmatis_MC2_155 DGWVQAYDPAGPVGSK-------------------------IANSSAVAG
TH_3810|M.thermoresistible__bu AGFGVPTTIQFPAG----------------------------------SC
MAB_4284c|M.abscessus_ATCC_199 VGSHVGGGISESLGG------------------------------SGSVG
MAV_4827|M.avium_104 PGAGTPGGGLGGFGG-----------------------------GHAPAP
MLBr_01556|M.leprae_Br4923 TNVNLASASDAIIIGFN-----------------------VRAEGKATEL
.
MUL_4280|M.ulcerans_Agy99 GGGAGGAGGISFTGAGGQGGAGG---------TGGQLSGNGGSGGTGGEG
MMAR_5207|M.marinum_M GGGAGGAGGISFTGAGGQGGAGG---------TGGQLSGNGGSGGTGGEG
Rv0746|M.tuberculosis_H37Rv SGGAGGAGGFGFL--GGDGGAGG---------NAGLLLSSGGAGGFGGFG
Mb0286c|M.bovis_AF2122/97 YGGAGGAGGYSNIGAGGAGGAGG---------NAGMLSGSGGSGGTGGAS
Mflv_5091|M.gilvum_PYR-GCK EDGDAGSGGSG-INGGAGGAGG-----------AGGEGGEGGDGGKGGAG
Mvan_1264|M.vanbaalenii_PYR-1 DAGDPGSEAVD-INGGAGGAGG-----------AGGEGGEGGAGGAGGDG
MSMEG_0868|M.smegmatis_MC2_155 NGGDGGVNGTGGASGGDGGNGGNTSVWKSGGQTADGEHNTGGNGGNGGDG
TH_3810|M.thermoresistible__bu TSRAVSREGIMPSSRAASARAG-----------AACASSTSRSRRSFCCS
MAB_4284c|M.abscessus_ATCC_199 GSTAVGGGAHTSAINDALGGSGS----------VGGSTAVGGGAHTSAIN
MAV_4827|M.avium_104 GGGLGGGGGHAPAPGGGLGGFGG-------------GHSGGGLGGLGGGH
MLBr_01556|M.leprae_Br4923 ASREGVEIRYYLVIYQAIDDIEK--------ALRGMLKPIYEENQLGRAE
MUL_4280|M.ulcerans_Agy99 DY----VGGADS-------GGAGGAGGN-AGLTGDG---------GNGG-
MMAR_5207|M.marinum_M DY----VGGADS-------GGAGGTGGN-AGLTGDG---------GNGGN
Rv0746|M.tuberculosis_H37Rv TAGG--VGGAGGNAGWLGFGGAGGVGGS-AGLIGTG---------GNGGN
Mb0286c|M.bovis_AF2122/97 GAAKGGVGGNGGTAGVFGNGGDGGAGGFGAGTGGNGGVGGNAVLIGNGGN
Mflv_5091|M.gilvum_PYR-GCK AE--------GG------AGGGGGAGGSGAGGAG-----------GAGGS
Mvan_1264|M.vanbaalenii_PYR-1 SE--------GG------AGGSGGAGGSGTGGAG-----------GAGGS
MSMEG_0868|M.smegmatis_MC2_155 SEPGPGGNGAGG------AGGNGGTGGTTAGGSGNG---------GNGGN
TH_3810|M.thermoresistible__bu RA------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 ESMNSSINASHS-------SSMNESFGSSMGSHGAAG-------TGFEAQ
MAV_4827|M.avium_104 K-------------------------------------------------
MLBr_01556|M.leprae_Br4923 IRALFRSSKVGIIAGCIISSGVVRRNAKVRLLRDNIVVTDNLTVTSLRRE
MUL_4280|M.ulcerans_Agy99 --SGGTPG-SPGGGGTGGALIGQDGLARLAVTGR-----
MMAR_5207|M.marinum_M GGSGGTPG-SPGGGGTGGALIGQDGLDGSP---------
Rv0746|M.tuberculosis_H37Rv GGTGANAG-SPGTGGAGGLLLGQNGLNGLP---------
Mb0286c|M.bovis_AF2122/97 GGNGGKAGGTPGAGGTSGLLIGENGLNGLP---------
Mflv_5091|M.gilvum_PYR-GCK GGSGGSGG-SGGSGGAAGDSDD-----------------
Mvan_1264|M.vanbaalenii_PYR-1 GGSGGSGG-AGGSGGAAGDSD------------------
MSMEG_0868|M.smegmatis_MC2_155 GGNGGADG-TPGTAGTTGANNP-----------------
TH_3810|M.thermoresistible__bu ---------------------------------------
MAB_4284c|M.abscessus_ATCC_199 GHAQGHASETAHTTLPGAEHH------------------
MAV_4827|M.avium_104 ---------------------------------------
MLBr_01556|M.leprae_Br4923 KDDVTEVREGFECGMTLGYSDIKEGDVIESYELVEKQRA