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LSYVMAVPEIIEAAAADLAAASQTTQIVAAAEDEVSAAIATVLSSHGQGYQVLSARALEFHTRLAQALSA GAGAYSGAEASSAGLLAAVNEPIAALTGRPLIGNGANGTPGLGTDGAPGGWLIGNGGAGGSGAAGSAGGA GGAAGLIGAGGAGGAGGSSTGGAGGTGGAGGAGGWLFGPGGVGGAGGSSSSAGGAGGVGGAGGLFGGGGL GGAGGAGVSASGGAGGAGGAGGALAGFLGAGGGDGGAGGSGVNHEGGAGGAGGAGGLIAGTGGNGGAGGT DAYSRGGAGGAGGDAGLLFGSGGAGGTGGTGGTDMSDSGGTGGAGGNAGLLFGSGGAGGAGGAAVALNDV GGAGGAGGNAGLFGNGGVGGVGGVGAGDGGAGGRAGLVIGNGGAGGAGGESFGFGAGVGGAGGNGGNGVL IGNGGNAGTGGTGLSTGSTGAGGISGLLLGLDGFNAPASTSALHNLQQQALGVINEPTQALTGRPLIGNG TPGAAGSGTDGTPGGWLLGDGGAGGSGAANTGASGGAGGAAGLLGTGGTGGAGARLAGGAGGTGGAGGAG GWLLGDGGGGGGGGSGGGGGASGGTGGTGGAGGLLSAGGAGGVGGAGFNDGGDGGAGGSGGLLGGLVGAG GGAGGNGGAGFGGTPGNGGAGGDAGLLGGPGGTGGAGGYNTSGPGGNGGSGGNAGTLFGSGGGGGNGGSG YSGIGGTGGTGGSAGLVFSDAGAGGFGGFGSTAGGTGGTGGNAVLLGGGGAGGAGGISFTGAGGQGGAGG TGGQLSGNGGSGGTGGEGDYVGGADSGGAGGTGGNAGLTGDGGNGGNGGSGGTPGSPGGGGTGGALIGQD GLDGSP
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. marinum M | MMAR_5207 | - | - | 100% (846) | PE-PGRS family protein, PE_PGRS9_2 |
| M. marinum M | MMAR_4399 | - | 0.0 | 65.47% (921) | PE-PGRS family protein |
| M. marinum M | MMAR_4398 | - | 0.0 | 63.04% (928) | PE-PGRS family protein, PE_PGRS9_3 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0767 | PE_PGRS9 | 0.0 | 60.14% (883) | PE-PGRS family protein |
| M. gilvum PYR-GCK | Mflv_5091 | - | 1e-149 | 44.11% (807) | triple helix repeat-containing collagen |
| M. tuberculosis H37Rv | Rv0746 | PE_PGRS9 | 0.0 | 61.49% (831) | PE-PGRS family protein |
| M. leprae Br4923 | MLBr_01556 | infB | 6e-10 | 38.24% (102) | translation initiation factor IF-2 |
| M. abscessus ATCC 19977 | MAB_4284c | - | 7e-49 | 34.10% (519) | hypothetical protein MAB_4284c |
| M. avium 104 | MAV_4827 | - | 1e-24 | 43.41% (182) | hypothetical protein MAV_4827 |
| M. smegmatis MC2 155 | MSMEG_0868 | - | 1e-125 | 35.06% (1078) | hypothetical protein MSMEG_0868 |
| M. thermoresistible (build 8) | TH_3810 | - | 3e-40 | 40.21% (281) | PUTATIVE - |
| M. ulcerans Agy99 | MUL_4280 | - | 0.0 | 83.42% (766) | PE-PGRS family protein |
| M. vanbaalenii PYR-1 | Mvan_1264 | - | 1e-151 | 45.83% (779) | triple helix repeat-containing collagen |
CLUSTAL 2.0.9 multiple sequence alignment
MMAR_5207|M.marinum_M --------------------------------------------------
MUL_4280|M.ulcerans_Agy99 --------------------------------------------------
Mb0767|M.bovis_AF2122/97 --------------------------------------------------
Rv0746|M.tuberculosis_H37Rv --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_1264|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_0868|M.smegmatis_MC2_155 MHERLRERAGGVRKTLSDFAEGAGLKPSDTDDTRSPLRKPKFPAALAPES
TH_3810|M.thermoresistible__bu --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 --------------------------------------------------
MAV_4827|M.avium_104 --------------------------------------------------
MLBr_01556|M.leprae_Br4923 --------------------------------------------------
MMAR_5207|M.marinum_M --------------------------------------------------
MUL_4280|M.ulcerans_Agy99 --------------------------------------------------
Mb0767|M.bovis_AF2122/97 --------------------------------------------------
Rv0746|M.tuberculosis_H37Rv --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_1264|M.vanbaalenii_PYR-1 -------------------MMFLAPPGGPGPISAAIQLTSTGSEATEP--
MSMEG_0868|M.smegmatis_MC2_155 PLPDLKPRWERPTTAPDSETPSITQPQGRDTAADPAEQQATSTNTTDQPT
TH_3810|M.thermoresistible__bu --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 --------------------------------------------------
MAV_4827|M.avium_104 --------------------------------------------------
MLBr_01556|M.leprae_Br4923 --------------------------------------------------
MMAR_5207|M.marinum_M ------------------------------------MSYVMAVPEIIEAA
MUL_4280|M.ulcerans_Agy99 ------------------------------------MSYVMAVPEIIEAA
Mb0767|M.bovis_AF2122/97 ------------------------------------MSFVLAMPEVLGSA
Rv0746|M.tuberculosis_H37Rv ------------------------------------MSFVLAMPEVLGSA
Mflv_5091|M.gilvum_PYR-GCK --------------------------------------MVTFGGGATPTP
Mvan_1264|M.vanbaalenii_PYR-1 ------------------------------------WYVVSFGGSGAPTP
MSMEG_0868|M.smegmatis_MC2_155 SDSLGAQPTAQVARQVQAPATDPAPAAPSLRPISGLLSVVTLGTTLIPNA
TH_3810|M.thermoresistible__bu --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 ------------------------------------MSIIDFILNLFRDP
MAV_4827|M.avium_104 --------------------------------------------------
MLBr_01556|M.leprae_Br4923 --------------------------------MAGKARVHELAKELGVTS
MMAR_5207|M.marinum_M AAD---------------------------------------LAAASQTT
MUL_4280|M.ulcerans_Agy99 AS----------------------------------------TAAASQTA
Mb0767|M.bovis_AF2122/97 ATDLAALGSV---------------------------LGAADAAAAATTT
Rv0746|M.tuberculosis_H37Rv ATDLAALGSV---------------------------LGAADAAAAATTT
Mflv_5091|M.gilvum_PYR-GCK ----------------------------------------TSLGAAAVDL
Mvan_1264|M.vanbaalenii_PYR-1 ----------------------------------------NNLAASLVDL
MSMEG_0868|M.smegmatis_MC2_155 PTEPADMPGVWAVMAWARRQPMYSDPAMRTTVNPQAQLPVPTVASAVLDP
TH_3810|M.thermoresistible__bu --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 ----------------------------------------VEAASYVADP
MAV_4827|M.avium_104 --------------------------------------------------
MLBr_01556|M.leprae_Br4923 KEVLARLNEQ---------------------------GEFVKSASSTVEA
MMAR_5207|M.marinum_M Q---------------------------------------IVAAAEDEVS
MUL_4280|M.ulcerans_Agy99 Q---------------------------------------TVAAAEDEVS
Mb0767|M.bovis_AF2122/97 G---------------------------------------IVAAVQDEVS
Rv0746|M.tuberculosis_H37Rv G---------------------------------------IVAAAQDEVS
Mflv_5091|M.gilvum_PYR-GCK S------------------------GTSCG----------LICNGQDGTG
Mvan_1264|M.vanbaalenii_PYR-1 S------------------------GTSCG----------LICNGQDGTG
MSMEG_0868|M.smegmatis_MC2_155 TQIVNWLIYQPLHAAGQQFWVVSPIGSTLGGVINTISGQYLIGNGINGTA
TH_3810|M.thermoresistible__bu --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 EAA-------------------------------------LANAGLSAVS
MAV_4827|M.avium_104 ------------------------------------------MNIVLGVS
MLBr_01556|M.leprae_Br4923 PVARRLRESFG----------------------------GIKPAADKGAE
MMAR_5207|M.marinum_M AA-----IATVLSSHGQGYQVLSARALEFHTRLAQALS--AGAGAYSGAE
MUL_4280|M.ulcerans_Agy99 AA-----IATVLSSHGQGYQVLSARALEFHTRLAQALS--AGAGAYSGAE
Mb0767|M.bovis_AF2122/97 AA-----IAALFSAHGRAYQVASAQAAAVHAQFVEALS--AGAGAYASAE
Rv0746|M.tuberculosis_H37Rv AA-----IAALFSAHGRAYQVASAQAAAVHAQFVEALS--AGAGAYASAE
Mflv_5091|M.gilvum_PYR-GCK QN-----GGILFGNGGSGWNSDVVGMDGGNGGNGGLFGGNGGNGGNGLGG
Mvan_1264|M.vanbaalenii_PYR-1 QN-----GGILFGNGGSGWNSEIAGVSGGNGGNAGLFGGNGGNGGNGLGS
MSMEG_0868|M.smegmatis_MC2_155 DNPNGGTGGLLFGDGGHGYDGSAAGLAGGNGGNAGLFG-NGGNGGVGWAG
TH_3810|M.thermoresistible__bu --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 AAQVGAVMPVVAESVASNYGYQSQWVNTGN----PIHDLSGNLQNYYAAQ
MAV_4827|M.avium_104 MAPSSIQMVVLEGEYADGATVEEDAIDVTGADDAATASAPDRVISAILGT
MLBr_01556|M.leprae_Br4923 QVATKAQAKRLGESLDQTLDRALDKAVAGNGATTAAPVQVDHSAAVVPIV
MMAR_5207|M.marinum_M ASSAG------------LLAAVNEPIAALTGRPLIG------NGANGTPG
MUL_4280|M.ulcerans_Agy99 ASSAG------------LLAAVNEPIAALTGRPLIG------NGANGTPG
Mb0767|M.bovis_AF2122/97 AAGAAVLANPAQSVQQDLLAAVNAQSVALTGRPLIG------NGANGAPG
Rv0746|M.tuberculosis_H37Rv AAGAAVLANPAQSVQQDLLAAVNAQSVALTGRPLIG------NGANGAPG
Mflv_5091|M.gilvum_PYR-GCK GNGGNGGNAGAFALFGNGGNGGNGGVGVVGATGAVG--APGVAGATGATG
Mvan_1264|M.vanbaalenii_PYR-1 GDGGNGGDAGLFSLFGRGGNGGNGGVGIAGATGAVG--APGVAGATGATG
MSMEG_0868|M.smegmatis_MC2_155 LDGGNGGSGG--LLMGIGGAGGAGGVGADGTSAHVDGGTGGTGGTGGGTG
TH_3810|M.thermoresistible__bu --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 PDGPSILSPSLLSPRDNDFLSHNDTDFASHNPIASGNQVMSPSGNVDSFN
MAV_4827|M.avium_104 REGAADAGLQLSSIGVTWTDQLEAAALRDALAARRIDNVMLVSAFLAAAA
MLBr_01556|M.leprae_Br4923 AGEGPSTAHREELAPPAGQPSEQPGVPLPGQQGTPAAPHPGHPGMPTGPH
MMAR_5207|M.marinum_M --LGTDGAPGGWLIGNGGAGGSGAAGS--AGGAGG--------------A
MUL_4280|M.ulcerans_Agy99 --LGTDGAPGGWLIGNDGAGGSGAAGS--AGGAGG--------------A
Mb0767|M.bovis_AF2122/97 --TGANGAPGGWLLGNGGAGGSAAAGSGLPGGAGG--------------A
Rv0746|M.tuberculosis_H37Rv --TGANGAPGGWLLGNGGAGGSAAAGSGLPGGAGG--------------A
Mflv_5091|M.gilvum_PYR-GCK VTSGVVGGNGEDAVGYGATGAAGAAGAAGAAGAAG--------------A
Mvan_1264|M.vanbaalenii_PYR-1 VTSNVTGGNGADAVGYGATGAAGAAGAAGAAGKAG--------------A
MSMEG_0868|M.smegmatis_MC2_155 GTGGIGGTGGGLFGLLGHSGSTGAAGAAGNGGDGGNGGFGYVLIAGPNVT
TH_3810|M.thermoresistible__bu --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 RGPLLDLSFGDLQFGNRDTTAIGDGAVAVGGSNSG---------------
MAV_4827|M.avium_104 LAQNVGGAMGYERTAVLLVEPDTATLAVVETSDGS---------------
MLBr_01556|M.leprae_Br4923 PGPAPKPGGRPPRVGNNPFSSAQSVARPIPRPPAPRPS-----------A
MMAR_5207|M.marinum_M AGLIGAGGAG---GAGGSSTGGAGGTGGAGGAGG---------------W
MUL_4280|M.ulcerans_Agy99 AGLIGAGGAGGAGGAGGSSTGGAGGTGGAGGAGE---------------W
Mb0767|M.bovis_AF2122/97 AGLFGTGGAG---GAGGSSTVGDGGAGGAGGSGG---------------W
Rv0746|M.tuberculosis_H37Rv AGLFGTGGAG---GAGGSSTVGDGEAGGAGGSGG---------------W
Mflv_5091|M.gilvum_PYR-GCK VGSAGAAGEAGETGTWG--NAGLPGKAGDAGGAG----------------
Mvan_1264|M.vanbaalenii_PYR-1 VGSAGTAGSAGAPGVWG--NAGLPGAAGAAGGAG----------------
MSMEG_0868|M.smegmatis_MC2_155 VGSETRGGTGGAGGTGGQSTAAGPGKGGGGGGGGGGAILIGANGGTVDGH
TH_3810|M.thermoresistible__bu ----------------------VDGDGGSGGRTG----------------
MAB_4284c|M.abscessus_ATCC_199 -PIASGQGSTAVNGDVRDSNIINADHGSNVGVDQ----------------
MAV_4827|M.avium_104 ------------IPDVYKQQIRAESYGDAAGQLS----------------
MLBr_01556|M.leprae_Br4923 SPSSMSPRPGGAVGGGGPRPPRTGVPRPGGGRPG---------------A
*
MMAR_5207|M.marinum_M LFGPGGVGG------AGGSSSSAGGAG--------------GVGGAGGLF
MUL_4280|M.ulcerans_Agy99 LFGPGGVGG------AGGSSSSAGGAG--------------GVGGAGGLF
Mb0767|M.bovis_AF2122/97 LLGTGGVGG------VGGLGAGAGGAG--------------GVGGAGGLL
Rv0746|M.tuberculosis_H37Rv LLGTGGVGG------VGGLGAGAGGAG--------------GVGGAGGLL
Mflv_5091|M.gilvum_PYR-GCK AVGAAGAAG------TVGTAGATGGTG---------------TGANGGAG
Mvan_1264|M.vanbaalenii_PYR-1 AIGTAGVAG------AAGTAGATGGTG---------------VGGNGGAG
MSMEG_0868|M.smegmatis_MC2_155 AIGGNGGNGGNGSTTAAGGNGGTGGTGRVIAEGTGSTAEGTATGGDGGHS
TH_3810|M.thermoresistible__bu LFSKLSRGG-------------DGGDG-----------------------
MAB_4284c|M.abscessus_ATCC_199 --SQTRVGG---------DYTNVSGHG-----------------SADIDK
MAV_4827|M.avium_104 ----AMVAG---------LEKLESLPG-------------------GLLL
MLBr_01556|M.leprae_Br4923 PVGGRSDAG--------GGNYRGGGVG------------ALPGGGSGGFR
* . *
MMAR_5207|M.marinum_M GGGGLGGAGGAGV------------SASGGAGG------AGGAGGALAGF
MUL_4280|M.ulcerans_Agy99 GGG-LGGAGGAGV------------SASGGAGG------AGGAGGALAGF
Mb0767|M.bovis_AF2122/97 GAGGHGGAGGLG-------------AVTGGVGG------AGGAGGLLAGL
Rv0746|M.tuberculosis_H37Rv GAGGHGGAGGLG-------------AVTGGVGG------TGGAGGLLAGL
Mflv_5091|M.gilvum_PYR-GCK GVGGVGGTGAAG--------------AAGGAGGLGETGTTGGAGGVGGQ-
Mvan_1264|M.vanbaalenii_PYR-1 QAGGIGGTGAAG--------------AAGQAGTAGETGVTGGVGGIGGQ-
MSMEG_0868|M.smegmatis_MC2_155 TGTGIGGNGGIGSVYAYGNNGAVSGTATGGRGGDGIDGGTGGAGGMGEIY
TH_3810|M.thermoresistible__bu ---GLGGNGGHG----------------------------GGTGIISLLS
MAB_4284c|M.abscessus_ATCC_199 SVTVVDDHSQRN---------------------------TTNINDSFNTD
MAV_4827|M.avium_104 VGSGVDVAPLKQ---------------------------VLQTTTFLDVS
MLBr_01556|M.leprae_Br4923 GRPGGGGHGGGG---------------------------RPGQRGGAAGA
.
MMAR_5207|M.marinum_M LGAGGGDGGAGGSG-VNHEGGAGGAGGAGG--LIAGTGGNGGAGGTDAYS
MUL_4280|M.ulcerans_Agy99 LGAGGSDGGAGGTG-VNHEGGAGGAGGAGG--LIAGTGGNGGAGGTDAYS
Mb0767|M.bovis_AF2122/97 LAGPGGAGGTGGRG-FLNDGGVGGAGGNAG--LLFGAGG-----------
Rv0746|M.tuberculosis_H37Rv LAGPGGAGGTGGRG-FLNNGGVGGAGGNAG--LLFGAGG-----------
Mflv_5091|M.gilvum_PYR-GCK -GTAGGTGGVGGIGGAGSTGAVGGVGGKG----IQGGQG-----------
Mvan_1264|M.vanbaalenii_PYR-1 -GTEGGTGGVGGVGGVGATGGAGGVGGKG----IQGGQG-----------
MSMEG_0868|M.smegmatis_MC2_155 SGADGEATGISAGGDGGSATGADSLGGRGGTSWVQAGYGPTTGGKASGTA
TH_3810|M.thermoresistible__bu LAGNGGNGG-----------------------------------------
MAB_4284c|M.abscessus_ATCC_199 RSTNIGSGNTTNTEIGSHNQANIGTSTSAG--------------------
MAV_4827|M.avium_104 VAEEPETALARGAALAAANAPLFASSTAALA-------------------
MLBr_01556|M.leprae_Br4923 FGRPGGAPRRGRKSKRQKRQEYDSMQAPVVG-------------------
.
MMAR_5207|M.marinum_M RGGAGGAGGDAGLLFGSGGAGGTGGTGGTD--------------------
MUL_4280|M.ulcerans_Agy99 RGGAGGAG-------------GTGGTGGTD--------------------
Mb0767|M.bovis_AF2122/97 ----------------------TGGSGGAG--------------------
Rv0746|M.tuberculosis_H37Rv ----------------------TGGSGGAG--------------------
Mflv_5091|M.gilvum_PYR-GCK --LQGGKG-------------GDGGAGGKGGDADSMGS------------
Mvan_1264|M.vanbaalenii_PYR-1 --LQGGQG-------------GDGGTGGTGGDATSMGE------------
MSMEG_0868|M.smegmatis_MC2_155 KAGHGGKA-------------SDGGKGGNGGDALVMAAGATGVATGNTAI
TH_3810|M.thermoresistible__bu ----------------------NGYRTTDN--------------------
MAB_4284c|M.abscessus_ATCC_199 ---------------------GSAAVGGNAG-------------------
MAV_4827|M.avium_104 --------------------------------------------------
MLBr_01556|M.leprae_Br4923 ---------------------GVRLPHGNGETIRLARG------------
MMAR_5207|M.marinum_M ------MSDSGGTGGAGGNAG--LLFG---------------SGGAGGAG
MUL_4280|M.ulcerans_Agy99 ------MSDSGGTGGAGGNAG--LLFG---------------SGGAGGAG
Mb0767|M.bovis_AF2122/97 ------LGGDGGAGGAGGNAG--VLFG---------------NAGSGGTG
Rv0746|M.tuberculosis_H37Rv ------LGGDGGAGGAGGNTG--VLFG---------------NAGSGGTG
Mflv_5091|M.gilvum_PYR-GCK ------AGATGGKGGNGGNGGRGGLFG---------------KGGNAGNG
Mvan_1264|M.vanbaalenii_PYR-1 ------AGATGGKGGNGGNGGRGSLFG---------------RGGNAGNG
MSMEG_0868|M.smegmatis_MC2_155 GGNGGAASANGAVGGNGGFTNIAAIHGSITDSSATSGHGGAAQGGNGGNG
TH_3810|M.thermoresistible__bu ------NALDGGHGGNGGNVGFFSLFN---------------LGGAGGWG
MAB_4284c|M.abscessus_ATCC_199 ------LAGNAGLAGNAGLAGNAGLAG---------------NAGLAGNA
MAV_4827|M.avium_104 ------YAQDPGTGAVDQYSLPDYLYVP--------------VDPEPGDD
MLBr_01556|M.leprae_Br4923 ----ASLSDFAEKIDANPAALVQALFNLG---------EMVTATQSVGDE
. : *
MMAR_5207|M.marinum_M GAAV------------ALNDVGGAGGAGGNAGLFGNGG-VGGVGGVG---
MUL_4280|M.ulcerans_Agy99 GAAV------------ALNDVGGAGGAGGNAGLFGNGG-VGGVGGVG---
Mb0767|M.bovis_AF2122/97 GFG---------------DTDGGAGGAGGDAGWLGSGG-VGGAGGFGE--
Rv0746|M.tuberculosis_H37Rv GFG---------------DTDGGAGGAGGDAGWLGSGG-VGGAGGFGE--
Mflv_5091|M.gilvum_PYR-GCK AD----------------------GGTGGAGGAGGTGG-TGGAGGTGG--
Mvan_1264|M.vanbaalenii_PYR-1 GN----------------------GGTGGNGGNGGTGG-TGGNGGTGG--
MSMEG_0868|M.smegmatis_MC2_155 GNGWVQAYDPNGPAGTTIDKGKAAGGNGGDGGFNGTGGATGGRGGDGAGA
TH_3810|M.thermoresistible__bu GS--------------------------GVDGVDVVGG------------
MAB_4284c|M.abscessus_ATCC_199 GLAG-------------------NAGLAGNAGLAGNAGLAGNAGLAGN--
MAV_4827|M.avium_104 ELAY---------------------SAVGEEDAESPTVVIEKLFLPED--
MLBr_01556|M.leprae_Br4923 TLELLG--------SEMNYNVQVVSPEDEDRELLEPFDLTYGEDQGDED-
MMAR_5207|M.marinum_M ----------------AGDG---GAGGR--AGLVIGNGGAGGAGGESFGF
MUL_4280|M.ulcerans_Agy99 ----------------AGDG---GAGGR--AGLVIGNGGAGGAGGESFGF
Mb0767|M.bovis_AF2122/97 ----------------TGDGGVGGAGGK--AGLLIGNGGAGGAG------
Rv0746|M.tuberculosis_H37Rv ----------------TGDGGVGGAGGK--AGLLIGNGGAGGAGGQ----
Mflv_5091|M.gilvum_PYR-GCK ---------------TGGTGGIGGAGSTGGTGGTGGTGGTGGTGGTG--G
Mvan_1264|M.vanbaalenii_PYR-1 ---------------TGGTGGIGGAGSTGGTGGTGGTGGTGGTGGTG--G
MSMEG_0868|M.smegmatis_MC2_155 SVWKANGQHSTGQTDTGGNGGRGGDGGTFVNAGANGNGGAGGAGGVSE-G
TH_3810|M.thermoresistible__bu ----------------------------------NPDGGTPGAHGES---
MAB_4284c|M.abscessus_ATCC_199 -------------------------------AGLAGNAGLAGNAGLAG--
MAV_4827|M.avium_104 -----------------------SEPRRRPVLLVGSGLAVVGISAVLALE
MLBr_01556|M.leprae_Br4923 -------ELQVRPPVVTVMGHVDHGKTRLLDTIRKANVREAEAGGITQHI
MMAR_5207|M.marinum_M GAGVGGAGGNGGNGVLIGNGGNAGTG----GTGLSTGSTGAGGISG----
MUL_4280|M.ulcerans_Agy99 GAGVGGAGGNGGNGVLIGNGGNAGTG----GTGLSTGSTGAGGISG----
Mb0767|M.bovis_AF2122/97 --------------VLIGNGGNAGIG----GTGPTAGDTGAGGISG----
Rv0746|M.tuberculosis_H37Rv GAVTGGTGGAGGDGVLIGNGGNAGIG----GTGPTAGDTGAGGISG----
Mflv_5091|M.gilvum_PYR-GCK TGGTGGTGGTGGKGGTGGTGGAGGTG----GDGGTGGTGGTGGTG-----
Mvan_1264|M.vanbaalenii_PYR-1 TGGTGGTGGTGGKGGTGGTGGDGGTG----GTGGTGGTGGTGGTG-----
MSMEG_0868|M.smegmatis_MC2_155 EGGTGGHGGDGGRGGDGALGGNGGTGGVGLGNGGKGGNGGNGGNGGTYVD
TH_3810|M.thermoresistible__bu -------HTPGVYTDRQGEDGEDGTG------TGIGGRGGNGG-------
MAB_4284c|M.abscessus_ATCC_199 ---NAGLAGNAGLAGNAGLAGNAGLA----GNAGLAGNAGLAGNAG----
MAV_4827|M.avium_104 IALAIGIRTTGTVALQPTPNQHLIVP-----TEQAPAPPPVQASAP----
MLBr_01556|M.leprae_Br4923 GAYQVGVDLDGSERLITFIDTPGHEAFTAMRARGAKATDIAILVVAADDG
.
MMAR_5207|M.marinum_M -LLLGLDGFNAPASTSALHNLQQQALGVINEPTQALTG-----RPLIGNG
MUL_4280|M.ulcerans_Agy99 -LLLGLDGFNAPASTSALHNLQQQALGVINEPTQALTG-----RPLIGNG
Mb0767|M.bovis_AF2122/97 -LLLGADGFNAPASASPLHTLKQQALAAINAPTQTLTG-----RPLIGNG
Rv0746|M.tuberculosis_H37Rv -LLLGADGFNTPASASPLHTLKQQALAAINAPTQTLTG-----RPLIGNG
Mflv_5091|M.gilvum_PYR-GCK ----GTGGTGGTGGAG-----------DGTGGTGGTGG----TGGQGGQG
Mvan_1264|M.vanbaalenii_PYR-1 ----GTGGTGGTGGAG-----------DGLGGTGGTGG----TGGFGGQG
MSMEG_0868|M.smegmatis_MC2_155 PSHTGAGGNGGNGGAGRIRVNNGTATGTATGGNGGNGGNGDADGHRGGKG
TH_3810|M.thermoresistible__bu ----SSSGTHPMAEDG--------------EHVKALDG---------RPG
MAB_4284c|M.abscessus_ATCC_199 --LAGNAGLAGNAAVAG---------NAAVAGNAAVAG----------NA
MAV_4827|M.avium_104 --QPKISVPEPVAAPKPLSPPVAAPLPAAPPPAAPPLP--------EAPP
MLBr_01556|M.leprae_Br4923 VMPQTVEAINHAQAADVPIVVAVNKIDKEGADPAKIRG-QLTEYGLVAED
MMAR_5207|M.marinum_M TPGAAG---------------SGTDGTPGGWLLGDGGAGGSGA-------
MUL_4280|M.ulcerans_Agy99 TPGAAG---------------SGTDGTPGGWLLGDG--------------
Mb0767|M.bovis_AF2122/97 TPGAVG---------------SGATGAPGGWLLGDGGAGGSGA-------
Rv0746|M.tuberculosis_H37Rv TPGAVG---------------SGATGAPGGWLLGDGGAGGSGA-------
Mflv_5091|M.gilvum_PYR-GCK GQGG-----------------TGGTGGQGG-LGGGGGTG-----------
Mvan_1264|M.vanbaalenii_PYR-1 GQGG-----------------TGGTGGQGG-LGGVGGTG-----------
MSMEG_0868|M.smegmatis_MC2_155 GDGGEALIRATVIGSNASGTATGGDGGNGGTLGATNGTGGAATIVAYNVV
TH_3810|M.thermoresistible__bu LDGG-----------------NGSHGGNGG--------------------
MAB_4284c|M.abscessus_ATCC_199 AVGGVLN--------------TGVSGAIGGSSHVGGAIN-----------
MAV_4827|M.avium_104 IPAAPP---------------VVPVPVVVPPVPVPVPVR-----------
MLBr_01556|M.leprae_Br4923 FGGDTMFIDISAKVG------TNIEALLEAVLLTADAALDLRAN------
.
MMAR_5207|M.marinum_M --------ANTGASGGAGGAAGLLGTGGTG----------------GAGA
MUL_4280|M.ulcerans_Agy99 ------------------GAAGLLGTGGTG----------------GAGA
Mb0767|M.bovis_AF2122/97 --------AGSGAPGGAGGAAGLWGTGGAG----------------GAGG
Rv0746|M.tuberculosis_H37Rv --------AGSGAPGGAGGAAGLWGTGGAGGAGGSSAGGGGAGGAGGAGG
Mflv_5091|M.gilvum_PYR-GCK ------------GQGGTGGTGGQGGTGGTGG-------------TGGTG-
Mvan_1264|M.vanbaalenii_PYR-1 ------------GTGGTGGTGGQGGTGGTGG-------------TGGTG-
MSMEG_0868|M.smegmatis_MC2_155 QANPQASGTATDGHGGSGINGGHGGNGGQGT-------------IEANGP
TH_3810|M.thermoresistible__bu ----------------HGGRGGFLGIGGSG----------------GWG-
MAB_4284c|M.abscessus_ATCC_199 -----------ESLGGSGSVGGSTAVGGGAHTG------------VGGG-
MAV_4827|M.avium_104 -----------IPVPDPVSPPQLLAPPRLSVP-------------QPVQP
MLBr_01556|M.leprae_Br4923 -----------SGMEAQGVAIEAHLDRGRGP-------------VATVLV
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MMAR_5207|M.marinum_M RLAGGAGGTGGAGGAG--GWLLGDGGGGGGGGSGGGGGASGGTGGTGGAG
MUL_4280|M.ulcerans_Agy99 RLAGGAGGTGGAGGAG--GWLLGDGGGGGGGASGGGGGASGGTGGTGGAG
Mb0767|M.bovis_AF2122/97 WLLG-DGGAGGIGGAS--TVLGGTGGGGGVGGLWGAGGAGG-AGGTGLVG
Rv0746|M.tuberculosis_H37Rv WLLG-DGGAGGIGGAS--TVLGGTGGGGGVGGLWGAGGAGG-AGGTGLVG
Mflv_5091|M.gilvum_PYR-GCK -------GTGGAGGDGGLGGLGGFGGSGGTGGQGGLGGPGGSTGGAGGAG
Mvan_1264|M.vanbaalenii_PYR-1 -------GTGGAGGDGGLGGLGGFGGVGGTGGQGGQGGPGGSTGGAGGAG
MSMEG_0868|M.smegmatis_MC2_155 SAVASGIGAGGNGGDGIDGGLGGNGGDGVVNTTANAANPGSATGTATGGD
TH_3810|M.thermoresistible__bu -------GHGGNGGDT--DADGGNGGDGGNGGSAGRGGTGGLRGVFGING
MAB_4284c|M.abscessus_ATCC_199 --VSTGVGVGSHVGGGISESLGGSGSVGGSTAVGGGAHTGVGGGVSTGVG
MAV_4827|M.avium_104 PVRVPQPPSPPQVGGTVPQSPPQHQTPPGEGTPPKPDGPGNYGGGHVPTP
MLBr_01556|M.leprae_Br4923 QRGTLRIGDSVVAGDAYGRVRRMVDEHGVDIEAALPSSPVQVIGFTSVPG
* . *
MMAR_5207|M.marinum_M G--LLSAGGAGGVGGAGFNDGGDGGAGGSGGLLGGLVGAGGGAGGNGGAG
MUL_4280|M.ulcerans_Agy99 G--LLSAGGAGGVG------------------------------------
Mb0767|M.bovis_AF2122/97 G--DGGAGGAGGTGG-----------------------------------
Rv0746|M.tuberculosis_H37Rv G--DGGAGGAGGTGG-----------------------------------
Mflv_5091|M.gilvum_PYR-GCK G--QAGTAGKGGLFG-----------------------------------
Mvan_1264|M.vanbaalenii_PYR-1 G--QAGVAGKGGLFG-----------------------------------
MSMEG_0868|M.smegmatis_MC2_155 GGKATGTASQGGNGGPSWV-------------------------------
TH_3810|M.thermoresistible__bu G---NGRAGLGGRGX-----------------------------------
MAB_4284c|M.abscessus_ATCC_199 VGSHVGGGISESLGG-----------------------------------
MAV_4827|M.avium_104 G-----AGGSGGSGG-----------------------------------
MLBr_01556|M.leprae_Br4923 AGDNFLVVDEDRIARQIADRRSARKRN-----------------------
MMAR_5207|M.marinum_M FGGTPGNGGAGGDAGLLGGPGGTGGAGGYNTSGPGGNGG------SGGNA
MUL_4280|M.ulcerans_Agy99 ------------------------GAGGYNTSGPGGNGG------SGGNA
Mb0767|M.bovis_AF2122/97 -----------LLAGLIGAGGGHGGTGGLNTNGDGGVGG------AGGNA
Rv0746|M.tuberculosis_H37Rv -----------LLAGLIGAGGGHGGTGGLSTNGDGGVGG------AGGNA
Mflv_5091|M.gilvum_PYR-GCK ------GSGSAGKAGATGAAGASGGKGAQGATGAQGATG------AQGAT
Mvan_1264|M.vanbaalenii_PYR-1 ------GSGSAGTAGVTGASGASGGKGAQGATGAQGATG------AQGAT
MSMEG_0868|M.smegmatis_MC2_155 ------QSGYGSTLGGNATGTATAGKGGEASNGGVAGNGGNALVMAAGTT
TH_3810|M.thermoresistible__bu -------------------XXXGGGVGAAVRSGNGVFSG-----------
MAB_4284c|M.abscessus_ATCC_199 ----------------------SGSVGGSTAVGGGAHTG---------VG
MAV_4827|M.avium_104 --------------------------GHVPTPGAGGSGG-----------
MLBr_01556|M.leprae_Br4923 ----ALAARSRKRISLEDLDSALKETSQLNLILKGDNAG--------TVE
. *
MMAR_5207|M.marinum_M GTLFGSGGGGGNGGSG-YSGIGGTGGTGGSAGLVFSDAGAGGFGGFGSTA
MUL_4280|M.ulcerans_Agy99 GTLFGSGGGG-NGGSG-YSGIGGTGGTG----------------------
Mb0767|M.bovis_AF2122/97 GMLAGPGGAGGAGGDGENLDTGGDGGAGG---------------------
Rv0746|M.tuberculosis_H37Rv GMLAGPGGAGGAGGDGENLDTGGDGGAGG---------------------
Mflv_5091|M.gilvum_PYR-GCK G-ATGAAGKAGATGAAGAAGAAGSAG----------------------TT
Mvan_1264|M.vanbaalenii_PYR-1 G-ATGASGAQGSAGSAGSAGVAGSAG----------------------TT
MSMEG_0868|M.smegmatis_MC2_155 GVATGNTATGGDGGAATTAGATGGAGGFSNIAAIH-----------GAIT
TH_3810|M.thermoresistible__bu ------GGGTPSAGFGVPTTIQFPAG------------------------
MAB_4284c|M.abscessus_ATCC_199 GGVNTGVGVGSHVGGGISESLGGSGS------------------------
MAV_4827|M.avium_104 ----SGGGHVPTPGTGGPGGTGGSGG------------------------
MLBr_01556|M.leprae_Br4923 ALEEALMGIQVDDEVALRVIDRGVGGITETN-------------------
. . ..
MMAR_5207|M.marinum_M GGTGGTGGNAVLLGGGGAGGAGGISFTG---------------AGGQGGA
MUL_4280|M.ulcerans_Agy99 -------GNAVLLGGGGAGGAGGISFTG---------------AGGQGGA
Mb0767|M.bovis_AF2122/97 -------SAGLLFGSGGAGGAGGFGFL-----------------GGDGGA
Rv0746|M.tuberculosis_H37Rv -------SAGLLFGSGGAGGAGGFGFL-----------------GGDGGA
Mflv_5091|M.gilvum_PYR-GCK GAQGSAGTNGA-NGANGSQGAAGKAGATGTTGATG--------AAGEDGD
Mvan_1264|M.vanbaalenii_PYR-1 GAQGSAGTNGA-NGANGSQGAAGKAGATGTTGATG--------AAGDAGD
MSMEG_0868|M.smegmatis_MC2_155 DSTAISGHGGAGNGGNGGKGADGWVQAYDPAGPVGSKIANSSAVAGNGGD
TH_3810|M.thermoresistible__bu --------------------------------------------SCTSRA
MAB_4284c|M.abscessus_ATCC_199 ------------VGGSTAVGGGAHTSAIN---------------DALGGS
MAV_4827|M.avium_104 -------GHVPTPGAGTPGGSGGGHLPFP---------------GAGSTP
MLBr_01556|M.leprae_Br4923 ---VNLASASDAIIIGFNVRAEGKATELASREGVEIRYYLVIYQAIDDIE
MMAR_5207|M.marinum_M GGTGGQLSGNGGSGGTGG-----------EGDY--VGGADS-------GG
MUL_4280|M.ulcerans_Agy99 GGTGGQLSGNGGSGGTGG-----------EGDY--VGGADS-------GG
Mb0767|M.bovis_AF2122/97 GGNAGLLLSSGGAGGFGG-----------FGTAGGVGGAGGNAGWLGFGG
Rv0746|M.tuberculosis_H37Rv GGNAGLLLSSGGAGGFGG-----------FGTAGGVGGAGGNAGWLGFGG
Mflv_5091|M.gilvum_PYR-GCK AGSGGSG-INGGAGGAGG-----------AGGEGGEGGDGGK------GG
Mvan_1264|M.vanbaalenii_PYR-1 PGSEAVD-INGGAGGAGG-----------AGGEGGEGGAGGA------GG
MSMEG_0868|M.smegmatis_MC2_155 GGVNGTGGASGGDGGNGGNTSVWKSGGQTADGEHNTGGNGGN------GG
TH_3810|M.thermoresistible__bu VSREGIMPSSRAASARAG--------------------------------
MAB_4284c|M.abscessus_ATCC_199 GSVGGSTAVGGGAHTSAIN----------ESMNSSINASHSS--------
MAV_4827|M.avium_104 GGSGGGHLPTPGAGTPGG----------------GLGGFGGG--------
MLBr_01556|M.leprae_Br4923 KALRGMLKPIYEENQLGRAEIRALFRSSKVGIIAGCIISSGVVRRNAKVR
. . .
MMAR_5207|M.marinum_M AG----------------------------------------------GT
MUL_4280|M.ulcerans_Agy99 AG----------------------------------------------GA
Mb0767|M.bovis_AF2122/97 AGGIGGIGGNANGGAGGNGGTGGQLWGSGGAGGEGGAALSVGDTGGAGGV
Rv0746|M.tuberculosis_H37Rv AG----------------------------------------------GV
Mflv_5091|M.gilvum_PYR-GCK AGAE-------------------------------------------GGA
Mvan_1264|M.vanbaalenii_PYR-1 DGSE-------------------------------------------GGA
MSMEG_0868|M.smegmatis_MC2_155 DGSEPGPGGN-----------------------------------GAGGA
TH_3810|M.thermoresistible__bu --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 --------------------------------------------------
MAV_4827|M.avium_104 --------------------------------------------------
MLBr_01556|M.leprae_Br4923 LLRDN-----------------------------------------IVVT
MMAR_5207|M.marinum_M GGNAGLTGD-GGNGGNGGSGGTPGSPGGGGTGGALIGQDGLDGSP-----
MUL_4280|M.ulcerans_Agy99 GGNAGLTGD-GGNGG---SGGTPGSPGGGGTGGALIGQDGLARLAVTGR-
Mb0767|M.bovis_AF2122/97 GGSAGLIGT-GGNGGNGGTGANAGSPGTGGAGGLLLGQNGLNGLP-----
Rv0746|M.tuberculosis_H37Rv GGSAGLIGT-GGNGGNGGTGANAGSPGTGGAGGLLLGQNGLNGLP-----
Mflv_5091|M.gilvum_PYR-GCK GGGGGAGGSGAGGAG--GAGGSGGSGGSGGSGGSGGAAGDSDD-------
Mvan_1264|M.vanbaalenii_PYR-1 GGSGGAGGSGTGGAG--GAGGSGGSGGSGGAGGSGGAAGDSD--------
MSMEG_0868|M.smegmatis_MC2_155 GGNGGTGGTTAGGSGNGGNGGNGGNGGADGTPGTAGTTGANNP-------
TH_3810|M.thermoresistible__bu ---------------------AACASSTSRSRRSFCCSRA----------
MAB_4284c|M.abscessus_ATCC_199 -SMNESFGSSMGSHGAAGTGFEAQGHAQGHASETAHTTLPGAEHH-----
MAV_4827|M.avium_104 HAPAPGGGLGGGGGHAPAPGGGLGGFGGGHSGGGLGGLGGGHK-------
MLBr_01556|M.leprae_Br4923 DNLTVTSLRREKDDVTEVREGFECGMTLGYSDIKEGDVIESYELVEKQRA
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