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MTLVDVVPGMVQAAANDLAGLNTTLNAANAAAATQITTVVAAAQDEVSAAIAAQFSGHGLAYQQLSTQVG VFSDQFVAALSASASGYSAAEAANTGPLQQLLTLINAPLLAATGRPLIGNGANGAPGTGANGGDGGWLLG DGGIGGSGTPGTVANPTGGVGGVGGAAGLLGSGGAGGAGGSSAFGDGGAGGVGGWLSGNAGAGGAGGPGL FGFNGGAGGAGGLLGAGGLGGAGGYGPGGVGGTGGAGGAGGLLAGLVGAGGGHGGTGGFGAGGTGGDGGA GGNAGLFGGPGGAGGTGGVGTGGDGGNGGAGGNAGALFGTGGAGGAGGSGVAGAGGVGGAGGNAGLLFSA GGVGGAGGYGSSDGGAGGAGGNGGLLYSNGGVGGTGGYGAAAAGGVGGAGGRAGLAIGGGGAGGAGGEGA TTGGDGGAGGTGVLIGNGGNAGVGGTGPAAGATGVGGTSGLLLGLDGFNAPASTSPLHTFQQQALGAVNA PVQTLTGRPLIGNGTPGAAGSGAAGTAGGWVFGDGGADGSGAMSTGADGGAGGAAGMWGTGGSGGAGPAG IGGGLTGGAGGAGGAGGYSSTADGGVGGAGGAGGLWGGGGIGGTGGFGALNGAAGGVGGAGGLLGGLVGA GGGDGGAGGYGLTGAGGAGGAGGNSGLLSGPGGSGGTGGAGAVADGAVGGAGGSAGLLFGSGRIGGDGGF GSNTGGAGGSGGLLLGQDGSDGLP
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. ulcerans Agy99 | MUL_2485 | - | - | 100% (724) | PE-PGRS family protein |
| M. ulcerans Agy99 | MUL_3062 | - | 0.0 | 62.86% (754) | PE-PGRS family protein |
| M. ulcerans Agy99 | MUL_4280 | - | 0.0 | 58.89% (737) | PE-PGRS family protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0767 | PE_PGRS9 | 0.0 | 61.49% (740) | PE-PGRS family protein |
| M. gilvum PYR-GCK | Mflv_5091 | - | 1e-124 | 44.83% (725) | triple helix repeat-containing collagen |
| M. tuberculosis H37Rv | Rv0746 | PE_PGRS9 | 0.0 | 61.87% (750) | PE-PGRS family protein |
| M. leprae Br4923 | MLBr_01183 | - | 6e-11 | 40.23% (87) | hypothetical protein MLBr_01183 |
| M. abscessus ATCC 19977 | MAB_4284c | - | 6e-49 | 33.12% (480) | hypothetical protein MAB_4284c |
| M. marinum M | MMAR_1391 | - | 0.0 | 95.16% (744) | PE-PGRS family protein, PE_PGRS9 |
| M. avium 104 | MAV_4827 | - | 2e-24 | 43.64% (165) | hypothetical protein MAV_4827 |
| M. smegmatis MC2 155 | MSMEG_0868 | - | 1e-102 | 40.64% (721) | hypothetical protein MSMEG_0868 |
| M. thermoresistible (build 8) | TH_3810 | - | 1e-38 | 38.62% (347) | PUTATIVE - |
| M. vanbaalenii PYR-1 | Mvan_1264 | - | 1e-122 | 44.83% (667) | triple helix repeat-containing collagen |
CLUSTAL 2.0.9 multiple sequence alignment
MUL_2485|M.ulcerans_Agy99 --------------------------------------------------
MMAR_1391|M.marinum_M --------------------------------------------------
Mb0767|M.bovis_AF2122/97 --------------------------------------------------
Rv0746|M.tuberculosis_H37Rv --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_1264|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_0868|M.smegmatis_MC2_155 MHERLRERAGGVRKTLSDFAEGAGLKPSDTDDTRSPLRKPKFPAALAPES
TH_3810|M.thermoresistible__bu --------------------------------------------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 --------------------------------------------------
MAV_4827|M.avium_104 --------------------------------------------------
MUL_2485|M.ulcerans_Agy99 ------------------MTLVDVVPGMVQAAANDLAGLNTTLNAANAAA
MMAR_1391|M.marinum_M ------------------MTLVDVVPGMVQAAANDLAGLNTTLNAANAAA
Mb0767|M.bovis_AF2122/97 ------------------MSFVLAMPEVLGSAATDLAALGSVLGAADAAA
Rv0746|M.tuberculosis_H37Rv ------------------MSFVLAMPEVLGSAATDLAALGSVLGAADAAA
Mflv_5091|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_1264|M.vanbaalenii_PYR-1 -------------------MMFLAPPGGPGPISAAIQLTSTGSEATEP--
MSMEG_0868|M.smegmatis_MC2_155 PLPDLKPRWERPTTAPDSETPSITQPQGRDTAADPAEQQATSTNTTDQPT
TH_3810|M.thermoresistible__bu --------------------------------------------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 ------------------MSIIDFILNLFRDPVEAASYVADPEAALANAG
MAV_4827|M.avium_104 ------------------MNIVLGVSMAPSSIQMVVLEGEYADGATVEED
MUL_2485|M.ulcerans_Agy99 ATQITTVVAAAQDEVSAAIAAQFSGHGLAYQQLSTQVGVFSDQFVAALSA
MMAR_1391|M.marinum_M ATQITTVVAAAQDEVSAAIAAQFSGHGLAYQQLSTQVGVFSDQFVAALSA
Mb0767|M.bovis_AF2122/97 AATTTGIVAAVQDEVSAAIAALFSAHGRAYQVASAQAAAVHAQFVEALSA
Rv0746|M.tuberculosis_H37Rv AATTTGIVAAAQDEVSAAIAALFSAHGRAYQVASAQAAAVHAQFVEALSA
Mflv_5091|M.gilvum_PYR-GCK --------------------------------------MVTFGGGATPTP
Mvan_1264|M.vanbaalenii_PYR-1 ------------------------------------WYVVSFGGSGAPTP
MSMEG_0868|M.smegmatis_MC2_155 SDSLGAQPTAQVARQVQAPATDPAPAAPSLRPISGLLSVVTLGTTLIPNA
TH_3810|M.thermoresistible__bu --------------------------------------------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 LSAVSAAQVGAVMPVVAESVASNYGYQSQWVNTGNPIHDLSGNLQNYYAA
MAV_4827|M.avium_104 AIDVTGADDAATASAPDRVISAILGTREGAADAGLQLSSIGVTWTDQLEA
MUL_2485|M.ulcerans_Agy99 SAS-----------------------------------------------
MMAR_1391|M.marinum_M SAS-----------------------------------------------
Mb0767|M.bovis_AF2122/97 GAG-----------------------------------------------
Rv0746|M.tuberculosis_H37Rv GAG-----------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK ----------------------------------------TSLGAAAVDL
Mvan_1264|M.vanbaalenii_PYR-1 ----------------------------------------NNLAASLVDL
MSMEG_0868|M.smegmatis_MC2_155 PTEPADMPGVWAVMAWARRQPMYSDPAMRTTVNPQAQLPVPTVASAVLDP
TH_3810|M.thermoresistible__bu --------------------------------------------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 Q-------------------------------------------------
MAV_4827|M.avium_104 AALR----------------------------------------------
MUL_2485|M.ulcerans_Agy99 ---------------------GYSAAEAANTGPLQ--------QLLTLIN
MMAR_1391|M.marinum_M ---------------------GYSAAEAANTGPLQ--------QLLTLIN
Mb0767|M.bovis_AF2122/97 ---------------------AYASAEAAGAAVLANPAQSVQQDLLAAVN
Rv0746|M.tuberculosis_H37Rv ---------------------AYASAEAAGAAVLANPAQSVQQDLLAAVN
Mflv_5091|M.gilvum_PYR-GCK S------------------------GTSCG----------LICNGQDGTG
Mvan_1264|M.vanbaalenii_PYR-1 S------------------------GTSCG----------LICNGQDGTG
MSMEG_0868|M.smegmatis_MC2_155 TQIVNWLIYQPLHAAGQQFWVVSPIGSTLGGVINTISGQYLIGNGINGTA
TH_3810|M.thermoresistible__bu --------------------------------------------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 ---------------------------PDGPSILSPSLLSPRDNDFLSHN
MAV_4827|M.avium_104 --------------------------------------DALAARRIDNVM
MUL_2485|M.ulcerans_Agy99 APLLAATGRPLIGNGANGAPG-----TGANGGDGGWLLGDGGIGGSGTPG
MMAR_1391|M.marinum_M APLLAATGRPLIGNGANGAPG-----TGANGGDGGWLLGDGGIGGSGTPG
Mb0767|M.bovis_AF2122/97 AQSVALTGRPLIGNGANGAPG-----TGANGAPGGWLLGNGGAGGSAAAG
Rv0746|M.tuberculosis_H37Rv AQSVALTGRPLIGNGANGAPG-----TGANGAPGGWLLGNGGAGGSAAAG
Mflv_5091|M.gilvum_PYR-GCK QN-----GGILFGNGGSGWNSDVVGMDGGNGGNGGLFGGNGGNGGNGLGG
Mvan_1264|M.vanbaalenii_PYR-1 QN-----GGILFGNGGSGWNSEIAGVSGGNGGNAGLFGGNGGNGGNGLGS
MSMEG_0868|M.smegmatis_MC2_155 DNPNGGTGGLLFGDGGHGYDGSAAGLAGGNGGNAGLFG-NGGNGGVGWAG
TH_3810|M.thermoresistible__bu ------------------------------------------------VD
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 DTDFASHNPIASGNQVMSPSGNVDSFNRGPLLDLSFGDLQFGNRDTTAIG
MAV_4827|M.avium_104 LVSAFLAAAALAQNVGGAMGYERTAVLLVEPDTATLAVVETSDGSIPDVY
MUL_2485|M.ulcerans_Agy99 TVANPTGGVGGVGGAAGLLGSGGAGGAGGSSAFG-----DGGAGGVG---
MMAR_1391|M.marinum_M TVANPTGGIGGAGGAAGLLGSGGAGGAGGSSAFG-----DGGAGGVGGAG
Mb0767|M.bovis_AF2122/97 -----SGLPGGAGGAAGLFGTGGAGGAGGSSTVG-----DGGAGGAGGSG
Rv0746|M.tuberculosis_H37Rv -----SGLPGGAGGAAGLFGTGGAGGAGGSSTVG-----DGEAGGAGGSG
Mflv_5091|M.gilvum_PYR-GCK G----NGGNGGNAGAFALFGNGGNGGNGGVGVVGATGAVG--APGVAGAT
Mvan_1264|M.vanbaalenii_PYR-1 G----DGGNGGDAGLFSLFGRGGNGGNGGVGIAGATGAVG--APGVAGAT
MSMEG_0868|M.smegmatis_MC2_155 L----DGGNGGSGG--LLMGIGGAGGAGGVGADGTSAHVDGGTGGTGGTG
TH_3810|M.thermoresistible__bu G----DGGSGGRTGLFSKLSRGGDGGDGGLG-------------GNGGHG
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 DG---AVAVGGSNSGPIASGQGSTAVNGDVRDSN---------IINADHG
MAV_4827|M.avium_104 KQQIRAESYGDAAGQLSAMVAGLEKLESLPG-------------GLLLVG
MUL_2485|M.ulcerans_Agy99 GWLSGNAGAGGAGGPGLFGFNGGAGGAG---GLLGAGGLGGAG-------
MMAR_1391|M.marinum_M GWLSGNAGAGGAGGPGLFGFNGGAGGAGGAGGLLGAGGLGGAG-------
Mb0767|M.bovis_AF2122/97 GWLLGTGGVGGVGGLGAG--AGGAGGVGGAGGLLGAGGHGGAG-------
Rv0746|M.tuberculosis_H37Rv GWLLGTGGVGGVGGLGAG--AGGAGGVGGAGGLLGAGGHGGAG-------
Mflv_5091|M.gilvum_PYR-GCK GATGVTSGVVGGNGEDAV--GYGATGAAGAAGAAGAAGAAG---------
Mvan_1264|M.vanbaalenii_PYR-1 GATGVTSNVTGGNGADAV--GYGATGAAGAAGAAGAAGKAG---------
MSMEG_0868|M.smegmatis_MC2_155 GGTGGTGGIGGTGGGLFG--LLGHSGSTGAAGAAGNGGDGGNGGFGYVLI
TH_3810|M.thermoresistible__bu GGTGIIS----------------------LLSLAGNGGNGG---------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 SNVGVDQSQTRVGGDYTNVSGHGSADIDKSVTVVDDHSQRNTTN------
MAV_4827|M.avium_104 SGVDVAPLKQVLQTTTFLDVSVAEEPETALARGAALAAANAPLF------
MUL_2485|M.ulcerans_Agy99 -----GYGPGGVGGTGGAGGAGGLLAGLVGAGGGHGGTGGFGAGGTGGDG
MMAR_1391|M.marinum_M -----GYGPGGVGGTGGAGGAGGLLAGLVGAGGGHGGTGGFGAGGTGGDG
Mb0767|M.bovis_AF2122/97 -----GLG-AVTGGVGGAGGAGGLLA------------------------
Rv0746|M.tuberculosis_H37Rv -----GLG-AVTGGVGGTGGAGGLLA------------------------
Mflv_5091|M.gilvum_PYR-GCK -----AVGSAGAAGEAGETGTWG--NAGLPGKAGDAGGAG----------
Mvan_1264|M.vanbaalenii_PYR-1 -----AVGSAGTAGSAGAPGVWG--NAGLPGAAGAAGGAG----------
MSMEG_0868|M.smegmatis_MC2_155 AGPNVTVGSETRGGTGGAGGTGGQSTAAGPGKGGGGGGGGGGAILIGANG
TH_3810|M.thermoresistible__bu ------NGYRTTDNNALDGGHGG---------------------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 ------INDSFNTDRSTNIGSGNTTN------------------------
MAV_4827|M.avium_104 ------ASSTAALAYAQDPGTGAVDQYSLP--------------------
MUL_2485|M.ulcerans_Agy99 GAGGNAGLFGGPGGAGGTGGVGTGGDGGNGGAG----------------G
MMAR_1391|M.marinum_M GAGGNAGLFGGPGGAGGTGGVGTGGDGGNGGAG----------------G
Mb0767|M.bovis_AF2122/97 ------GLLAGPGGAGGTGGRGFLNDGGVGGAG----------------G
Rv0746|M.tuberculosis_H37Rv ------GLLAGPGGAGGTGGRGFLNNGGVGGAG----------------G
Mflv_5091|M.gilvum_PYR-GCK ------AVGAAGAAG------TVGTAGATGGTG---------------TG
Mvan_1264|M.vanbaalenii_PYR-1 ------AIGTAGVAG------AAGTAGATGGTG---------------VG
MSMEG_0868|M.smegmatis_MC2_155 GTVDGHAIGGNGGNGGNGSTTAAGGNGGTGGTGRVIAEGTGSTAEGTATG
TH_3810|M.thermoresistible__bu ------------------------------------------------NG
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 -----TEIGSHNQANIGTSTSAGGSAAVGGNAG---------------LA
MAV_4827|M.avium_104 -----DYLYVPVDPEPGDDELAYSAVGEEDAES-----------------
MUL_2485|M.ulcerans_Agy99 NAGALFGTGGAGGAGGSG-----------VAGAGGVGGAGGNAGLLFSAG
MMAR_1391|M.marinum_M NAGALFGTGGAGGAGGSG-----------VAGAGGVGGAGGNAGLLFSAG
Mb0767|M.bovis_AF2122/97 NAGLLFGAGGTGGSGGAG-----------LGGDGGAGGAGGNAGVLFGNA
Rv0746|M.tuberculosis_H37Rv NAGLLFGAGGTGGSGGAG-----------LGGDGGAGGAGGNTGVLFGNA
Mflv_5091|M.gilvum_PYR-GCK ANGGAGGVGGVGGTGAAG--------------AAGGAGGLGETGTTGGAG
Mvan_1264|M.vanbaalenii_PYR-1 GNGGAGQAGGIGGTGAAG--------------AAGQAGTAGETGVTGGVG
MSMEG_0868|M.smegmatis_MC2_155 GDGGHSTGTGIGGNGGIGSVYAYGNNGAVSGTATGGRGGDGIDGGTGGAG
TH_3810|M.thermoresistible__bu GNVGFFSLFNLGG--------------------AGGWGGSGVDG------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 GNAGLAGNAGLAGNAGLAG----------NAGLAGNAGLAGNAGLAGNAG
MAV_4827|M.avium_104 -PTVVIEKLFLPEDSEPR---------------RRPVLLVGSGLAVVGIS
MUL_2485|M.ulcerans_Agy99 GVGGAGGYGSSDGGAGGAGGNGGLLYSNGGVGGTGG--------------
MMAR_1391|M.marinum_M GVGGAGGYGSSDGGAGGAGGNGGLLYSNGGVGGTGG--------------
Mb0767|M.bovis_AF2122/97 GSGGTGGFGDTDGGAGGAGGDAGWLGS-GGVGGAGG--------------
Rv0746|M.tuberculosis_H37Rv GSGGTGGFGDTDGGAGGAGGDAGWLGS-GGVGGAGG--------------
Mflv_5091|M.gilvum_PYR-GCK GVGGQ--GTAGGTGGVGGIGGAGSTGAVGGVGGKG----IQGGQG-----
Mvan_1264|M.vanbaalenii_PYR-1 GIGGQ--GTEGGTGGVGGVGGVGATGGAGGVGGKG----IQGGQG-----
MSMEG_0868|M.smegmatis_MC2_155 GMGEIYSGADGEATGISAGGDGGSATGADSLGGRGGTSWVQAGYGPTTGG
TH_3810|M.thermoresistible__bu ---------------VDVVGGNP---------------------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 LAGNAGLAGNAGLAGNAGLAGNAGLAGNAGLAGNAG--------------
MAV_4827|M.avium_104 AVLALEIALAIGIRTTGTVALQPTPNQHLIVPTEQAP-------------
MUL_2485|M.ulcerans_Agy99 ----------YGAAAAGGVGGAGGRAGLAIG-------------------
MMAR_1391|M.marinum_M ----------YGAAAAGGAGGAGGRAGLAIG-------------------
Mb0767|M.bovis_AF2122/97 ----------FGETGDGGVGGAGGKAGLLIG-------------------
Rv0746|M.tuberculosis_H37Rv ----------FGETGDGGVGGAGGKAGLLIG-------------------
Mflv_5091|M.gilvum_PYR-GCK --------LQGGKGGDGGAGGKGGDADSMGS------------------A
Mvan_1264|M.vanbaalenii_PYR-1 --------LQGGQGGDGGTGGTGGDATSMGE------------------A
MSMEG_0868|M.smegmatis_MC2_155 KASGTAKAGHGGKASDGGKGGNGGDALVMAAGATGVATGNTAIGGNGGAA
TH_3810|M.thermoresistible__bu ---------------DGGTPG-----------------------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 ------------LAGNAGLAGNAGLAGN----------------------
MAV_4827|M.avium_104 --------------APPPVQASAPQPKISVP-------------------
MUL_2485|M.ulcerans_Agy99 --GGGAGGAGGEGATTGGDGGAGGTG------------------------
MMAR_1391|M.marinum_M --GGGAGGAGGEGATTGGDGGAGGTG------------------------
Mb0767|M.bovis_AF2122/97 --NGGAGGAG----------------------------------------
Rv0746|M.tuberculosis_H37Rv --NGGAGGAGGQGAVTGGTGGAGGDG------------------------
Mflv_5091|M.gilvum_PYR-GCK GATGGKGGNGGNGGRGGLFG---------------KGGNAGNGAD-----
Mvan_1264|M.vanbaalenii_PYR-1 GATGGKGGNGGNGGRGSLFG---------------RGGNAGNGGN-----
MSMEG_0868|M.smegmatis_MC2_155 SANGAVGGNGGFTNIAAIHGSITDSSATSGHGGAAQGGNGGNGGNGWVQA
TH_3810|M.thermoresistible__bu -AHGESHTPGVYTDRQ----------------------------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 ---AGLAGNAGLAGNAGLAG------------------------------
MAV_4827|M.avium_104 ---EPVAAPKPLSPPVAAPLP-----------------------------
MUL_2485|M.ulcerans_Agy99 ---------------VLIGNGGNAGVGGTGPAAGATGVGGTSG-------
MMAR_1391|M.marinum_M ---------------VLIGNGGNAGVGGTGPAAGATGVGGTSG-------
Mb0767|M.bovis_AF2122/97 ---------------VLIGNGGNAGIGGTGPTAGDTGAGGISG-------
Rv0746|M.tuberculosis_H37Rv ---------------VLIGNGGNAGIGGTGPTAGDTGAGGISG-------
Mflv_5091|M.gilvum_PYR-GCK -----------------GGTGGAGGAGGTGG-TGGAGGTGG---------
Mvan_1264|M.vanbaalenii_PYR-1 -----------------GGTGGNGGNGGTGG-TGGNGGTGG---------
MSMEG_0868|M.smegmatis_MC2_155 YDPNGPAGTTIDKGKAAGGNGGDGGFNGTGGATGGRGGDGAGASVWKANG
TH_3810|M.thermoresistible__bu ---------------------GEDGEDGTGTGIGGRGGNGG---------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 ----------------NAGLAGNAGLAGNAAVAGNAAVAGNAA-------
MAV_4827|M.avium_104 ----------------------AAPPPAAPPLPEAPPIPAAPP-------
MUL_2485|M.ulcerans_Agy99 -------LLLGLDGFNAPASTSPLHTFQQQALGAVNAPVQTLTGRPLIGN
MMAR_1391|M.marinum_M -------LLLGLDGFNAPASTSPLHTFQQQALGAVNAPVQTLTGRPLIGN
Mb0767|M.bovis_AF2122/97 -------LLLGADGFNAPASASPLHTLKQQALAAINAPTQTLTGRPLIGN
Rv0746|M.tuberculosis_H37Rv -------LLLGADGFNTPASASPLHTLKQQALAAINAPTQTLTGRPLIGN
Mflv_5091|M.gilvum_PYR-GCK --------TGGTGGIGGAGSTGGTGGTGGTGGTGGTGGTG-GTGGTGGTG
Mvan_1264|M.vanbaalenii_PYR-1 --------TGGTGGIGGAGSTGGTGGTGGTGGTGGTGGTG-GTGGTGGTG
MSMEG_0868|M.smegmatis_MC2_155 QHSTGQTDTGGNGGRGGDGGTFVNAGANGNGGAGGAGGVSEGEGGTGGHG
TH_3810|M.thermoresistible__bu -------SSSGTHPMAEDG--------EHVKALDGRPGLD---GGNGSHG
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 --------VAGNAAVGGVLNTGVSGAIGGSSHVGG--AINESLGGSGSVG
MAV_4827|M.avium_104 -------VVPVPVVVPPVPVPVPVRIPVPDPVSPPQLLAPPRLSVPQPVQ
MUL_2485|M.ulcerans_Agy99 GTPGAAGSGAAGTAGGWVF------GDGGADGSGAMS----------TGA
MMAR_1391|M.marinum_M GTPGAAGSGAAGTAGGWVF------GDGGAGGSGAMS----------TGA
Mb0767|M.bovis_AF2122/97 GTPGAVGSGATGAPGGWLL------GDGGAGGSGAAG----------SGA
Rv0746|M.tuberculosis_H37Rv GTPGAVGSGATGAPGGWLL------GDGGAGGSGAAG----------SGA
Mflv_5091|M.gilvum_PYR-GCK GTGGKGGTGGTGGAGGTG----GDGGTGGTGGTGGTG---------GTGG
Mvan_1264|M.vanbaalenii_PYR-1 GTGGKGGTGGTGGDGGTG----GTGGTGGTGGTGGTG---------GTGG
MSMEG_0868|M.smegmatis_MC2_155 GDGGRGGDGALGGNGGTGGVGLGNGGKGGNGGNGGNGGTYVDPSHTGAGG
TH_3810|M.thermoresistible__bu GNGGHGGRGGFLGIGGSG-------GWGGHGGNGGD-----------TDA
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 GSTAVGGGAHTGVGGGVSTG----VGVGSHVGGG------------ISES
MAV_4827|M.avium_104 PPVRVPQPPSPPQVGGTVPQ-----SPPQHQTPPGEG---------TPPK
MUL_2485|M.ulcerans_Agy99 DGGAGGAAG------------MWGTGGSGGAG------------------
MMAR_1391|M.marinum_M DGGAGGAAG------------MWGTGGSGGAG------------------
Mb0767|M.bovis_AF2122/97 PGGAGGAAG------------LWGTGGAG---------------------
Rv0746|M.tuberculosis_H37Rv PGGAGGAAG------------LWGTGGAGGAGG-----------------
Mflv_5091|M.gilvum_PYR-GCK TGGTGGAG-----------DGTGGTGGTGG----TGGQGGQGGQGG----
Mvan_1264|M.vanbaalenii_PYR-1 TGGTGGAG-----------DGLGGTGGTGG----TGGFGGQGGQGG----
MSMEG_0868|M.smegmatis_MC2_155 NGGNGGAGRIRVNNGTATGTATGGNGGNGGNGDADGHRGGKGGDGGEALI
TH_3810|M.thermoresistible__bu DGGNGGDG---------------GNGGSAG--------------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 LGGSGSVG---------------GSTAVGG--------------------
MAV_4827|M.avium_104 PDGPGNYGG--------------GHVPTPG--------------------
MUL_2485|M.ulcerans_Agy99 ------------PAGIGGGLTGGAGGAGGAG---------------GYSS
MMAR_1391|M.marinum_M ------------AAGIGGGLTGGAGGAGGAGGWLT--GTGGAGGSGGYSS
Mb0767|M.bovis_AF2122/97 --------------GAGGWLLG-DGGAGGIGG----------------AS
Rv0746|M.tuberculosis_H37Rv --SSAGGGGAGGAGGAGGWLLG-DGGAGGIGG----------------AS
Mflv_5091|M.gilvum_PYR-GCK -------------TGGTGGQGG-LGGGGGTG-------------------
Mvan_1264|M.vanbaalenii_PYR-1 -------------TGGTGGQGG-LGGVGGTG-------------------
MSMEG_0868|M.smegmatis_MC2_155 RATVIGSNASGTATGGDGGNGGTLGATNGTGGAATIVAYNVVQANPQASG
TH_3810|M.thermoresistible__bu -------------RGGTGGLRGVFGINGGNG-------------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 --------------GAHTGVGGGVSTGVGVG-------------------
MAV_4827|M.avium_104 -------------AGGSGGSGGGHVPTPGAG-------------------
MUL_2485|M.ulcerans_Agy99 TADGGVGGAGGAGGLWGGGGIGGTGGFG--------ALNG--AAGGVGGA
MMAR_1391|M.marinum_M TADGGVGGAGGAGGLWGGGGIGGTGGFG--------ALNG--AAGGVGGA
Mb0767|M.bovis_AF2122/97 TVLGGTGGGGGVGGLWGAGGAGGAGGTG--------LVGGDGGAGGAGGT
Rv0746|M.tuberculosis_H37Rv TVLGGTGGGGGVGGLWGAGGAGGAGGTG--------LVGGDGGAGGAGGT
Mflv_5091|M.gilvum_PYR-GCK ----GQGGTGGTGGQGGTGGTGGTGGTG--------GTGGAGGDGGLGGL
Mvan_1264|M.vanbaalenii_PYR-1 ----GTGGTGGTGGQGGTGGTGGTGGTG--------GTGGAGGDGGLGGL
MSMEG_0868|M.smegmatis_MC2_155 TATDGHGGSGINGGHGGNGGQGTIEANGPSAVASGIGAGGNGGDGIDGGL
TH_3810|M.thermoresistible__bu -----RAGLGGRGXXXXGGGVGAAVRSG---------------NGVFSGG
MLBr_01183|M.leprae_Br4923 -----MPLFLNAEPQALTAAANTLEGLS---------------AATVASN
MAB_4284c|M.abscessus_ATCC_199 ----SHVGGGISESLGGSGSVGGSTAVG---------------GGAHTGV
MAV_4827|M.avium_104 ------GSGGSGGGHVPTPGTGGPGGTG----------------GSGGGH
. . . . .
MUL_2485|M.ulcerans_Agy99 GGLLGGLVGAGGGDGGAGGYGLTGAGGAGG------------------AG
MMAR_1391|M.marinum_M GGLLGGLVGAGGGDGGAGGYGLTGAGGAGG------------------AG
Mb0767|M.bovis_AF2122/97 GGLLAGLIGAGGGHGGTGGLNTNGDGGVGG------------------AG
Rv0746|M.tuberculosis_H37Rv GGLLAGLIGAGGGHGGTGGLSTNGDGGVGG------------------AG
Mflv_5091|M.gilvum_PYR-GCK GGFGGSGGTGGQGGLGGPGGSTGGAGGAGG--QAGTAGKGGLFG----GS
Mvan_1264|M.vanbaalenii_PYR-1 GGFGGVGGTGGQGGQGGPGGSTGGAGGAGG--QAGVAGKGGLFG----GS
MSMEG_0868|M.smegmatis_MC2_155 GGNGGDGVVNTTANAANPGSATGTATGGDGGKATGTASQGGNGGPSWVQS
TH_3810|M.thermoresistible__bu GGTPSAGFGVPTTIQFPAGSCTSRAVSREG--------------------
MLBr_01183|M.leprae_Br4923 AAAAQLTTEIAPPAADDVSILLAHFFSGHG--------------------
MAB_4284c|M.abscessus_ATCC_199 GGGVNTGVGVGSHVGGGISESLGGSGSVGG--------------------
MAV_4827|M.avium_104 VPTPGAGTPGGSGGGHLPFPGAGSTPGGSG--------------------
. *
MUL_2485|M.ulcerans_Agy99 GNSGLLSGPGGSGGTGGAG-AVADGAVGGAG--------GSAGLLFGSGR
MMAR_1391|M.marinum_M GNSGLLSGPGGSGGTGGAG-AVADGGVGGAG--------GSAGLLFGSGG
Mb0767|M.bovis_AF2122/97 GNAGMLAGPGGAGGAGGDGENLDTGGDGGAG--------GSAGLLFGSGG
Rv0746|M.tuberculosis_H37Rv GNAGMLAGPGGAGGAGGDGENLDTGGDGGAG--------GSAGLLFGSGG
Mflv_5091|M.gilvum_PYR-GCK GSAGKAGATGAAGASGGKGAQGATGAQGATG------AQGATG-ATGAAG
Mvan_1264|M.vanbaalenii_PYR-1 GSAGTAGVTGASGASGGKGAQGATGAQGATG------AQGATG-ATGASG
MSMEG_0868|M.smegmatis_MC2_155 GYGSTLGGNATGTATAGKGGEASNGGVAGNGGNALVMAAGTTGVATGNTA
TH_3810|M.thermoresistible__bu ----IMPSSRAASARAG---------------------------AACASS
MLBr_01183|M.leprae_Br4923 ---RQYQAHASQGATNHQD--------------------LIQSLLTSSSA
MAB_4284c|M.abscessus_ATCC_199 -STAVGGGAHTSAINDALGGSGSVGGSTAVG--------GGAHTSAINES
MAV_4827|M.avium_104 --GGHLPTPGAGTPGGGLG---------GFG--------GGHAPAPGGGL
MUL_2485|M.ulcerans_Agy99 IGGDGGFGSNTG--------------------------------------
MMAR_1391|M.marinum_M IGGDGGFGSNTGGAGGAGGNAGLLFSSAGAGGFGGFGVANGGGSGGAGGN
Mb0767|M.bovis_AF2122/97 AGGAGGFG-FLGGDGGAGGNAGLLLSSGGAGGFGGFG--TAGGVGGAGGN
Rv0746|M.tuberculosis_H37Rv AGGAGGFG-FLGGDGGAGGNAGLLLSSGGAGGFGGFG--TAGGVGGAGGN
Mflv_5091|M.gilvum_PYR-GCK KAGATGAAGAAGAAGSAG-----------TTGAQGSAGTNGA-NGANGSQ
Mvan_1264|M.vanbaalenii_PYR-1 AQGSAGSAGSAGVAGSAG-----------TTGAQGSAGTNGA-NGANGSQ
MSMEG_0868|M.smegmatis_MC2_155 TGGDGGAATTAGATGGAGGFSNIAAIHGAITDSTAISGHGGAGNGGNGGK
TH_3810|M.thermoresistible__bu TSRSRRSFCCSRA-------------------------------------
MLBr_01183|M.leprae_Br4923 YAGTETANHDSL--------------------------------------
MAB_4284c|M.abscessus_ATCC_199 MNSSINASHSSSMNESFG--------------------------------
MAV_4827|M.avium_104 GGGGGHAPAPGGGLGGFG--------------------------------
MUL_2485|M.ulcerans_Agy99 --------------------------------------------------
MMAR_1391|M.marinum_M AGLLGCGGAGGAGGLGIAGTGGSGGAGGTGGVLLGTGGAGGSGAESLGVG
Mb0767|M.bovis_AF2122/97 AGWLGFGGAGGIGGIGGNANGGAGGNGGTGGQLWGSGGAGGEGGAALSVG
Rv0746|M.tuberculosis_H37Rv AGWLGFGGAG----------------------------------------
Mflv_5091|M.gilvum_PYR-GCK GAAGKAGATGTTGATG--------AAGEDGDAGSGGSG-INGGAGGAGG-
Mvan_1264|M.vanbaalenii_PYR-1 GAAGKAGATGTTGATG--------AAGDAGDPGSEAVD-INGGAGGAGG-
MSMEG_0868|M.smegmatis_MC2_155 GADGWVQAYDPAGPVGSKIANSSAVAGNGGDGGVNGTGGASGGDGGNGGN
TH_3810|M.thermoresistible__bu --------------------------------------------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 --------------------------------------------------
MAV_4827|M.avium_104 --------------------------------------------------
MUL_2485|M.ulcerans_Agy99 -----------------------------------------GAGGSGGLL
MMAR_1391|M.marinum_M DSGGAGGMGGNAVLIGTGGNGGNGGVGAG--------TGTRGAGGSGGLL
Mb0767|M.bovis_AF2122/97 DTGGAGGVGGSAGLIGTGGNGGNGGTGAN--------AGSPGTGGAGGLL
Rv0746|M.tuberculosis_H37Rv ------GVGGSAGLIGTGGNGGNGGTGAN--------AGSPGTGGAGGLL
Mflv_5091|M.gilvum_PYR-GCK ----------AGGEGGEGGDGGKGGAGAE--------GGAGGGGGAGGSG
Mvan_1264|M.vanbaalenii_PYR-1 ----------AGGEGGEGGAGGAGGDGSE--------GGAGGSGGAGGSG
MSMEG_0868|M.smegmatis_MC2_155 TSVWKSGGQTADGEHNTGGNGGNGGDGSEPGPGGNGAGGAGGNGGTGGTT
TH_3810|M.thermoresistible__bu --------------------------------------------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 -----------------SSMGSHGAAGTG--------FEAQGHAQGHASE
MAV_4827|M.avium_104 --------------------------------------GGHSGGGLGGLG
MUL_2485|M.ulcerans_Agy99 LGQDGSDGLP-----------------------
MMAR_1391|M.marinum_M LGQDGSDGLP-----------------------
Mb0767|M.bovis_AF2122/97 LGQNGLNGLP-----------------------
Rv0746|M.tuberculosis_H37Rv LGQNGLNGLP-----------------------
Mflv_5091|M.gilvum_PYR-GCK AGGAG--GAGGSGGSGGSGGSGGSGGAAGDSDD
Mvan_1264|M.vanbaalenii_PYR-1 TGGAG--GAGGSGGSGGSGGAGGSGGAAGDSD-
MSMEG_0868|M.smegmatis_MC2_155 AGGSGNGGNGGNGGNGGADGTPGTAGTTGANNP
TH_3810|M.thermoresistible__bu ---------------------------------
MLBr_01183|M.leprae_Br4923 ---------------------------------
MAB_4284c|M.abscessus_ATCC_199 TAHTTLPGAEHH---------------------
MAV_4827|M.avium_104 GGHK-----------------------------