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SYFIAVPDELALAATELDSIGAALSVANVAAALPTTGILAAGADDVSTAIAASTFHTQFVRALNLSGGAY AAADVANASPLQTLEQDLLGVLNAPTQALLGGPLIGDGADGTAPGQGGGAGGLLYGNGGSGAAGTNTGVA GGAGGAAGLVGNGGSGGAGGGGAAGGAGGNGGWLFGAGGNGGFGGAATGLGPGGAGGYGGHGGWLYGSGG TGGDGGFAKGGNGGAGGAGGDAGLLGAGGSGGTGGAGATSGPASSHFAGGAGGAGGHGGLLYGDGETGGF GGDGGVGGAGGAGGGGGAAGLVGAGGAGGNGGAGLGILGEAGGNDGGGGAGGSGGNGFGTIGGTGGSGGR GGDARLIGNGGDGGAGAPGGNSAPPGDGGVGGAGGTLSGTPGATGALG*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. ulcerans Agy99 | MUL_3990 | - | - | 100% (399) | PE-PGRS family protein |
| M. ulcerans Agy99 | MUL_4399 | - | e-117 | 53.26% (445) | PE-PGRS family protein |
| M. ulcerans Agy99 | MUL_3507 | - | e-114 | 49.90% (479) | PE-PGRS family protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1121 | PE_PGRS22 | 1e-118 | 55.30% (443) | PE-PGRS family protein |
| M. gilvum PYR-GCK | Mflv_5091 | - | 4e-73 | 44.44% (414) | triple helix repeat-containing collagen |
| M. tuberculosis H37Rv | Rv1091 | PE_PGRS22 | 1e-118 | 55.30% (443) | PE-PGRS family protein |
| M. leprae Br4923 | MLBr_01556 | infB | 1e-09 | 35.71% (126) | translation initiation factor IF-2 |
| M. abscessus ATCC 19977 | MAB_4284c | - | 1e-33 | 33.25% (388) | hypothetical protein MAB_4284c |
| M. marinum M | MMAR_4127 | - | 0.0 | 83.51% (467) | PE-PGRS family protein |
| M. avium 104 | MAV_4827 | - | 9e-23 | 41.72% (163) | hypothetical protein MAV_4827 |
| M. smegmatis MC2 155 | MSMEG_0868 | - | 4e-62 | 45.90% (329) | hypothetical protein MSMEG_0868 |
| M. thermoresistible (build 8) | TH_3810 | - | 5e-38 | 40.83% (289) | PUTATIVE - |
| M. vanbaalenii PYR-1 | Mvan_1264 | - | 2e-73 | 50.49% (307) | triple helix repeat-containing collagen |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_5091|M.gilvum_PYR-GCK -------------------------------MVTFGGGATPTPTSLGAAA
Mvan_1264|M.vanbaalenii_PYR-1 MMFLAPPGGPGPISAAIQLTSTGSEATEPWYVVSFGGSGAPTPNNLAASL
MUL_3990|M.ulcerans_Agy99 -----------------------------------MSYFIAVPDELALAA
MMAR_4127|M.marinum_M -----------------------------------MSYFIAVPDELALAA
Mb1121|M.bovis_AF2122/97 -----------------------------------MSFVIAAPEALVAVA
Rv1091|M.tuberculosis_H37Rv -----------------------------------MSFVIAAPEALVAVA
MSMEG_0868|M.smegmatis_MC2_155 -----------------------MHERLRERAGGVRKTLSDFAEGAGLKP
TH_3810|M.thermoresistible__bu --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 --------------------------------MSIIDFILNLFRDPVEAA
MAV_4827|M.avium_104 -------------------------------MNIVLGVSMAPSSIQMVVL
MLBr_01556|M.leprae_Br4923 ----------------------------MAGKARVHELAKELGVTSKEVL
Mflv_5091|M.gilvum_PYR-GCK VDLSGTSCGLICNGQDGTGQNGGILF------------------------
Mvan_1264|M.vanbaalenii_PYR-1 VDLSGTSCGLICNGQDGTGQNGGILF------------------------
MUL_3990|M.ulcerans_Agy99 TELDSIGAALSVANVAAALPTTGIL-------------------------
MMAR_4127|M.marinum_M TELDSIGAALSVANVAAALPTTGIL-------------------------
Mb1121|M.bovis_AF2122/97 SDLAGIGSALAEANAAALAPTTALL-------------------------
Rv1091|M.tuberculosis_H37Rv SDLAGIGSALAEANAAALAPTTALL-------------------------
MSMEG_0868|M.smegmatis_MC2_155 SDTDDTRSPLRKPKFPAALAPESPLPDLKPRWERPTTAPDSETPSITQPQ
TH_3810|M.thermoresistible__bu -----------VDGDGGSGGRTGLFS------------------------
MAB_4284c|M.abscessus_ATCC_199 SYVADPEAALANAGLSAVSAAQVGAVMP----------------------
MAV_4827|M.avium_104 EGEYADGATVEEDAIDVTGADDAAT-------------------------
MLBr_01556|M.leprae_Br4923 ARLNEQGEFVKSASSTVEAPVARRLRESFG--------------------
Mflv_5091|M.gilvum_PYR-GCK --GNGGSGWNSDVVGMDGGNGGNGGLFGGNGGNGGNGLGGGNGGNGG---
Mvan_1264|M.vanbaalenii_PYR-1 --GNGGSGWNSEIAGVSGGNGGNAGLFGGNGGNGGNGLGSGDGGNGG---
MUL_3990|M.ulcerans_Agy99 --AAGADDVSTAIA----------------ASTFHTQFVRALNLSGG---
MMAR_4127|M.marinum_M --AAGADDVSTAIAALFAGHAQAYQALSTAASTFHTQFVRALNLSGG---
Mb1121|M.bovis_AF2122/97 --AAGADEVSAAIAALFGAHGQAYQTVSAQASAFHAQFVQALTGGGG---
Rv1091|M.tuberculosis_H37Rv --AAGADEVSAAIAALFGAHGQAYQTVSAQASAFHAQFVQALTGGGG---
MSMEG_0868|M.smegmatis_MC2_155 GRDTAADPAEQQATSTNTTDQPTSDSLGAQPTAQVARQVQAPATDPAPAA
TH_3810|M.thermoresistible__bu -----------------------------KLSRGGDGGDGGLGGNGG---
MAB_4284c|M.abscessus_ATCC_199 -VVAESVASNYGYQSQWVNTGNPIHDLSGNLQNYYAAQPDGPSILSP---
MAV_4827|M.avium_104 --ASAPDRVISAILGTREGAADAGLQLSSIGVTWTDQLEAAALRDALAAR
MLBr_01556|M.leprae_Br4923 -GIKPAADKGAEQVATKAQAKRLGESLDQTLDRALDKAVAGNGATTAAP-
.
Mflv_5091|M.gilvum_PYR-GCK ---------------------NAGAFALFGN-------------------
Mvan_1264|M.vanbaalenii_PYR-1 ---------------------DAGLFSLFGR-------------------
MUL_3990|M.ulcerans_Agy99 --------------------AYAAADVANAS-------------------
MMAR_4127|M.marinum_M --------------------AYAAADAANAS-------------------
Mb1121|M.bovis_AF2122/97 --------------------AYAAAEAANVS-------------------
Rv1091|M.tuberculosis_H37Rv --------------------AYAAAEAANVS-------------------
MSMEG_0868|M.smegmatis_MC2_155 PSLRPISGLLSVVTLGTTLIPNAPTEPADMPGVWAVMAWARRQPMYSDPA
TH_3810|M.thermoresistible__bu --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 ----------------------SLLSPRDND-------------------
MAV_4827|M.avium_104 ----------------------RIDNVMLVS-------------------
MLBr_01556|M.leprae_Br4923 --------------------VQVDHSAAVVP-------------------
Mflv_5091|M.gilvum_PYR-GCK ------------GGNGGNGGVG----------------------------
Mvan_1264|M.vanbaalenii_PYR-1 ------------GGNGGNGGVG----------------------------
MUL_3990|M.ulcerans_Agy99 -----------PLQTLEQDLLG----------------------------
MMAR_4127|M.marinum_M -----------PLQTLEQDLLG----------------------------
Mb1121|M.bovis_AF2122/97 -----------AAQSTDQRLLD----------------------------
Rv1091|M.tuberculosis_H37Rv -----------AAQSTDQRLLD----------------------------
MSMEG_0868|M.smegmatis_MC2_155 MRTTVNPQAQLPVPTVASAVLDPTQIVNWLIYQPLHAAGQQFWVVSPIGS
TH_3810|M.thermoresistible__bu --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 -----------FLSHNDTDFAS----------------------------
MAV_4827|M.avium_104 ------------AFLAAAALAQN---------------------------
MLBr_01556|M.leprae_Br4923 -----------IVAGEGPSTAHR--------------------------E
Mflv_5091|M.gilvum_PYR-GCK -VVGATGAVGAPGVAGATGATGVTSGVVGGNGEDAVG-YGATGAAGAAG-
Mvan_1264|M.vanbaalenii_PYR-1 -IAGATGAVGAPGVAGATGATGVTSNVTGGNGADAVG-YGATGAAGAAG-
MUL_3990|M.ulcerans_Agy99 VLNAPTQALLGGPLIG-DGADGTAPGQGGGAGGLLYG-NGGSGAAGTNTG
MMAR_4127|M.marinum_M VLNAPTQALLGRPLIG-DGADGTAPGQGGGAGGLLYG-NGGSGAAGTNTG
Mb1121|M.bovis_AF2122/97 LINGPTQALLGRPLIG-DGANG-GPGQDGGPGGLLYG-NGGNGGTSTTAG
Rv1091|M.tuberculosis_H37Rv LINGPTQALLGRPLIG-DGANG-GPGQDGGPGGLLYG-NGGNGGTSTTAG
MSMEG_0868|M.smegmatis_MC2_155 TLGGVINTISGQYLIG-NGINGTADNPNGGTGGLLFG-DGGHGYDGSAAG
TH_3810|M.thermoresistible__bu -HGGGTGIISLLSLAG-NGGNGGNGYRTTDNNALDGG-HGGNG-------
MAB_4284c|M.abscessus_ATCC_199 -HNPIASGNQVMSPSGNVDSFNRGPLLDLSFGDLQFG-NRDTTAIGDGAV
MAV_4827|M.avium_104 -VGGAMGYERTAVLLVEPDTATLAVVETSDGSIPDVY-KQQIRAESYGDA
MLBr_01556|M.leprae_Br4923 ELAPPAGQPSEQPGVPLPGQQGTPAAPHPGHPGMPTGPHPGPAPKPGGRP
. .
Mflv_5091|M.gilvum_PYR-GCK -AAGAAGAAGAVGSAGAAGEAGETGTWGNAGLPGKAGDAGGAGAVGAAG-
Mvan_1264|M.vanbaalenii_PYR-1 -AAGAAGKAGAVGSAGTAGSAGAPGVWGNAGLPGAAGAAGGAGAIGTAG-
MUL_3990|M.ulcerans_Agy99 VAGGAGGAAGLVGNGGSGGAGGGGAAGGAGGNGGWLFG------------
MMAR_4127|M.marinum_M VAGGAGGDAGLIGNGGSGGAGGGGAAGGAGGNGGWLFG------------
Mb1121|M.bovis_AF2122/97 VAGGNGGAAGLIGNGGAGGGGGAGAAGGNGGAGGWLYGNGGAGGAGGT--
Rv1091|M.tuberculosis_H37Rv VAGGNGGAAGLIGNGGAGGGGGAGAAGGNGGAGGWLYGNGGAGGAGGT--
MSMEG_0868|M.smegmatis_MC2_155 LAGGNGGNAGLFGNGGNGGVGWAGLDGGNGGSGGLLMGIGGAGGAGGVGA
TH_3810|M.thermoresistible__bu ---GNVGFFSLFNLGGAGGWGGSGVDGVDVVGGNPDGGTPG---------
MAB_4284c|M.abscessus_ATCC_199 AVGGSNSGPIASGQGSTAVNGDVRDSNIINADHGSNVGVDQSQTRVGG--
MAV_4827|M.avium_104 AGQLSAMVAGLEKLESLPGGLLLVGSGVDVAPLKQVLQTTTFLDVSVAE-
MLBr_01556|M.leprae_Br4923 PRVGNNPFSSAQSVARPIPRPPAPRPSASPSSMSPRPGGAVGGGGPRPP-
Mflv_5091|M.gilvum_PYR-GCK ----------AAGTVGTAGATGGTG-------------------------
Mvan_1264|M.vanbaalenii_PYR-1 ----------VAGAAGTAGATGGTG-------------------------
MUL_3990|M.ulcerans_Agy99 ----------AGGNGGFGGAATGLG-------------------------
MMAR_4127|M.marinum_M ----------AGGNGGFGGAATGLG-------------------------
Mb1121|M.bovis_AF2122/97 ----SVIPGVAGGNGGAGGSAGLWG-------------------------
Rv1091|M.tuberculosis_H37Rv ----SVIPGVAGGNGGAGGSAGLWG-------------------------
MSMEG_0868|M.smegmatis_MC2_155 DGTSAHVDGGTGGTGGTGGGTGGTGGIGGTGGGLFGLLGHSGSTGAAGAA
TH_3810|M.thermoresistible__bu ----------AHGESHTPGVYTD---------------------------
MAB_4284c|M.abscessus_ATCC_199 ---------DYTNVSGHGSADIDKS-------------------------
MAV_4827|M.avium_104 ----------EPETALARGAALAAAN------------------------
MLBr_01556|M.leprae_Br4923 ----------RTGVPRPGGGRPGAP-------------------------
.
Mflv_5091|M.gilvum_PYR-GCK ---------------------------TGANGGAGGVGGVGGTGAAGAAG
Mvan_1264|M.vanbaalenii_PYR-1 ---------------------------VGGNGGAGQAGGIGGTGAAGAAG
MUL_3990|M.ulcerans_Agy99 ---------------------------PGGAGGYGGHG------------
MMAR_4127|M.marinum_M ---------------------------PGGAGGAGGHG------------
Mb1121|M.bovis_AF2122/97 ---------------------------TGGAGGDGGNGRSGPVNVAGSAG
Rv1091|M.tuberculosis_H37Rv ---------------------------TGGAGGDGGNGRSGPVNVAGSAG
MSMEG_0868|M.smegmatis_MC2_155 GNGGDGGNGGFGYVLIAGPNVTVGSETRGGTGGAGGTGGQSTAAGPGKGG
TH_3810|M.thermoresistible__bu ---------------------------RQGEDGEDGTG------------
MAB_4284c|M.abscessus_ATCC_199 -------------------------VTVVDDHSQRNTTNINDSFNTDRST
MAV_4827|M.avium_104 -----------------------------APLFASSTAALAYAQDPGTGA
MLBr_01556|M.leprae_Br4923 ---------------------------VGGRSDAGGGNYRGGGVGALPGG
Mflv_5091|M.gilvum_PYR-GCK GAGGLGETGTTGGAGG----------------------VGGQGTAGGTG-
Mvan_1264|M.vanbaalenii_PYR-1 QAGTAGETGVTGGVGG----------------------IGGQGTEGGTG-
MUL_3990|M.ulcerans_Agy99 --------GWLYGSGG----------------------TGGDGG------
MMAR_4127|M.marinum_M --------GWLYGSGG----------------------TGGDGG------
Mb1121|M.bovis_AF2122/97 GNGGAGGAAGLFGDAG----------------------AGGNGGKGGAG-
Rv1091|M.tuberculosis_H37Rv GNGGAGGAAGLFGDAG----------------------AGGNGGKGGAG-
MSMEG_0868|M.smegmatis_MC2_155 GGGGGGGGAILIGANGGTVDGHAIGGNGGNGGNGSTTAAGGNGGTGGTGR
TH_3810|M.thermoresistible__bu -----------TGIGG----------------------RGGNGG------
MAB_4284c|M.abscessus_ATCC_199 NIGSGNTTNTEIGSHN----------------------QANIGTSTSAG-
MAV_4827|M.avium_104 VDQYSLPDYLYVPVDP----------------------EPGDDE------
MLBr_01556|M.leprae_Br4923 GSGGFRGRPGGGGHGG----------------------GGRPGQRGGAAG
.
Mflv_5091|M.gilvum_PYR-GCK -------------GVGGIGGAG----------------------------
Mvan_1264|M.vanbaalenii_PYR-1 -------------GVGGVGGVG----------------------------
MUL_3990|M.ulcerans_Agy99 ---------------FAKGGN-----------------------------
MMAR_4127|M.marinum_M ---------------FAKGGN-----------------------------
Mb1121|M.bovis_AF2122/97 ------GAAFSINFTAGDGGA-----------------------------
Rv1091|M.tuberculosis_H37Rv ------GAAFSINFTAGDGGA-----------------------------
MSMEG_0868|M.smegmatis_MC2_155 VIAEGTGSTAEGTATGGDGGHSTGTGIGGNGGIGSVYAYGNNGAVSGTAT
TH_3810|M.thermoresistible__bu ---------------SSSGTHP----------------------------
MAB_4284c|M.abscessus_ATCC_199 -------------GSAAVGGNAG---------------------------
MAV_4827|M.avium_104 ------------LAYSAVGEED----------------------------
MLBr_01556|M.leprae_Br4923 -------------AFGRPGGAPR---------------------------
*
Mflv_5091|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_1264|M.vanbaalenii_PYR-1 --------------------------------------------------
MUL_3990|M.ulcerans_Agy99 --------------------------------------------------
MMAR_4127|M.marinum_M --------------------------------------------------
Mb1121|M.bovis_AF2122/97 --------------------------------------------------
Rv1091|M.tuberculosis_H37Rv --------------------------------------------------
MSMEG_0868|M.smegmatis_MC2_155 GGRGGDGIDGGTGGAGGMGEIYSGADGEATGISAGGDGGSATGADSLGGR
TH_3810|M.thermoresistible__bu --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 --------------------------------------------------
MAV_4827|M.avium_104 --------------------------------------------------
MLBr_01556|M.leprae_Br4923 --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK ------------------------------STGAVGGVGGKGIQGGQGLQ
Mvan_1264|M.vanbaalenii_PYR-1 ------------------------------ATGGAGGVGGKGIQGGQGLQ
MUL_3990|M.ulcerans_Agy99 --------------------------------GGAGGAGGDAGLLGAGGS
MMAR_4127|M.marinum_M --------------------------------GGAGGAGGDAGLLGAGGS
Mb1121|M.bovis_AF2122/97 --------------------------------GGAGGSGGHALLWGAGGA
Rv1091|M.tuberculosis_H37Rv --------------------------------GGAGGSGGHALLWGAGGA
MSMEG_0868|M.smegmatis_MC2_155 GGTSWVQAGYGPTTGGKASGTAKAGHGGKASDGGKGGNGGDALVMAAGAT
TH_3810|M.thermoresistible__bu --------------------------------MAEDGEHVKALDGRPGLD
MAB_4284c|M.abscessus_ATCC_199 ------------------------------LAGNAGLAGNAGLAGNAGLA
MAV_4827|M.avium_104 --------------------------------AESPTVVIEKLFLPEDSE
MLBr_01556|M.leprae_Br4923 --------------------------------RGRKSKRQKRQEYDSMQA
Mflv_5091|M.gilvum_PYR-GCK G------GKGGDGGAGGKGGDADSMG---------------------SAG
Mvan_1264|M.vanbaalenii_PYR-1 G------GQGGDGGTGGTGGDATSMG---------------------EAG
MUL_3990|M.ulcerans_Agy99 ---------GGTGGAGATSGP----------------------------A
MMAR_4127|M.marinum_M ---------GGTGGAGATSGP----------------------------A
Mb1121|M.bovis_AF2122/97 ---------GGNGGSGGTGGAGGST------------------------A
Rv1091|M.tuberculosis_H37Rv ---------GGNGGSGGTGGAGGST------------------------A
MSMEG_0868|M.smegmatis_MC2_155 GVATGNTAIGGNGGAASANGAVGGNGGFTNIAAIHGSITDSSATSGHGGA
TH_3810|M.thermoresistible__bu ---------GGNGSHGG---------------------------------
MAB_4284c|M.abscessus_ATCC_199 G----NAGLAGNAGLAGNAGLAGNAG----------------------LA
MAV_4827|M.avium_104 PRRRPVLLVGSGLAVVGISAVLALEIA---------------------LA
MLBr_01556|M.leprae_Br4923 PVVGGVRLPHGNGETIRLARGASLSDFAEKIDAN-----------PAALV
.
Mflv_5091|M.gilvum_PYR-GCK ATGGKGG-------------------------NGGNGGRGGLFGKGGNAG
Mvan_1264|M.vanbaalenii_PYR-1 ATGGKGG-------------------------NGGNGGRGSLFGRGGNAG
MUL_3990|M.ulcerans_Agy99 SSHFAGG-------------------------AGGAGGHGGLLYGDG---
MMAR_4127|M.marinum_M SSHFAGG-------------------------AGGAGGHGGLLYGDG---
Mb1121|M.bovis_AF2122/97 GAGGNGG-------------------------AGGGGGTGGLLFGNGGAG
Rv1091|M.tuberculosis_H37Rv GAGGNGG-------------------------AGGGGGTGGLLFGNGGAG
MSMEG_0868|M.smegmatis_MC2_155 AQGGNGGNGGNGWVQAYDPNGPAGTTIDKGKAAGGNGGDGGFNGTGGATG
TH_3810|M.thermoresistible__bu --------------------------------NGGHGGRGGFLGIGG---
MAB_4284c|M.abscessus_ATCC_199 GNAGLAG-------------------------NAGLAGNAGLAGNAG---
MAV_4827|M.avium_104 IGIRTTG-----------------------TVALQPTPNQHLIVPTEQAP
MLBr_01556|M.leprae_Br4923 QALFNLG-------------------EMVTATQSVGDETLELLGSEMNYN
:
Mflv_5091|M.gilvum_PYR-GCK NGAD---------------GGTGGAGGAGGTGGTGGAGGTGGTGGTGGIG
Mvan_1264|M.vanbaalenii_PYR-1 NGGN---------------GGTGGNGGNGGTGGTGGNGGTGGTGGTGGIG
MUL_3990|M.ulcerans_Agy99 --------------------------ETGGFGGDG------------GVG
MMAR_4127|M.marinum_M --------------------------GTGGFGGDG------------GVG
Mb1121|M.bovis_AF2122/97 GHGA-AAGNGLAAGNGVSSSGGGGAGGTGGAGGDGGAGGAGGNARLWGVG
Rv1091|M.tuberculosis_H37Rv GHGA-AAGNGLAAGNGVSSSGGGGAGGTGGAGGDGGAGGAGGNARLWGVG
MSMEG_0868|M.smegmatis_MC2_155 GRGGDGAGASVWKANGQHSTGQTDTGGNGGRGGDGGTFVNAGANGNGGAG
TH_3810|M.thermoresistible__bu ------------------------SGGWGGHGGNGG-----------DTD
MAB_4284c|M.abscessus_ATCC_199 ------------------------LAGNAGLAGNAGLAGNAGLAGNAGLA
MAV_4827|M.avium_104 -----------------------APPPVQASAPQPKISVPEPVAAPKPLS
MLBr_01556|M.leprae_Br4923 VQVVSPEDEDRELLEPFDLTYGEDQGDEDELQVRPPVVTVMGHVDHGKTR
Mflv_5091|M.gilvum_PYR-GCK GAG----STGGTGGTGGTGGTGGTGGTG----------GTGGTGGTGGTG
Mvan_1264|M.vanbaalenii_PYR-1 GAG----STGGTGGTGGTGGTGGTGGTG----------GTGGTGGTGGTG
MUL_3990|M.ulcerans_Agy99 GAG----GAGGGGGAAG---------------------------------
MMAR_4127|M.marinum_M GAG----GAGGGGGAAG---------------------------------
Mb1121|M.bovis_AF2122/97 GAG----GAGGDGGAGGAGGKGGSGLSGNANGGAGGDSGRGGTGGAGGEG
Rv1091|M.tuberculosis_H37Rv GAG----GAGGDGGAGGAGGKGGSGLSGNANGGAGGDSGRGGTGGAGGEG
MSMEG_0868|M.smegmatis_MC2_155 GAGGVSEGEGGTGGHGGDGGRGGDGALGGNGGTGGVGLGNGGKGGNGGNG
TH_3810|M.thermoresistible__bu ADG----GNGGDGGNGG---------------------------------
MAB_4284c|M.abscessus_ATCC_199 GNAG-LAGNAGLAGNAG---------------------------------
MAV_4827|M.avium_104 PPVAAPLPAAPPPAAPP---------------------------------
MLBr_01556|M.leprae_Br4923 LLDTIRKANVREAEAGGITQHIGAYQVGVDLDGSERLITFIDTPGHEAFT
Mflv_5091|M.gilvum_PYR-GCK G---------KGGTGGTGGAGGTGGDGGTGGTGGTGGTGGTGGTGGTGGA
Mvan_1264|M.vanbaalenii_PYR-1 G---------KGGTGGTGGDGGTGGTGGTGGTGGTGGTGGTGGTGGTGGA
MUL_3990|M.ulcerans_Agy99 ----------LVGAGGAGGNGGAG--------------LGILGEAG----
MMAR_4127|M.marinum_M ----------LVGAGGAGGNGGAG--------------LGILGEAG----
Mb1121|M.bovis_AF2122/97 G-----AAGLLVGTGGHGGDGGAGGAAVKGGDGGAAAGTGIAGAGGRGGA
Rv1091|M.tuberculosis_H37Rv G-----AAGLLVGTGGHGGDGGAGGAAVKGGDGGAAAGTGIAGAGGRGGA
MSMEG_0868|M.smegmatis_MC2_155 GNGGTYVDPSHTGAGGNGGNGGAGRIRVNNGTATGTATGGNGGNGGNGDA
TH_3810|M.thermoresistible__bu ----------SAGRGGTGGLRGVFG------------INGGNGRAGLG--
MAB_4284c|M.abscessus_ATCC_199 ----------LAGNAGLAGNAGLAGNAAVAGNAAVAGNAAVAGNAAVG--
MAV_4827|M.avium_104 ----------LPEAPPIPAAPPVVPVPVVVPPVPVPVPVRIPVPDPVSPP
MLBr_01556|M.leprae_Br4923 AMRARGAKATDIAILVVAADDGVMPQTVEAINHAQAADVPIVVAVNKIDK
.
Mflv_5091|M.gilvum_PYR-GCK GDGTGGTGGTGG-----------TGGQGGQGGQGGTGGTGGQGGLGGG--
Mvan_1264|M.vanbaalenii_PYR-1 GDGLGGTGGTGG-----------TGGFGGQGGQGGTGGTGGQGGLGGV--
MUL_3990|M.ulcerans_Agy99 --------------------------------------------------
MMAR_4127|M.marinum_M --------------------------------------------------
Mb1121|M.bovis_AF2122/97 GGSGGSGGDGGGGAAGPAGWLFGDGGAGGNGGAAAAGGAGGQAGGGGGNG
Rv1091|M.tuberculosis_H37Rv GGSGGSGGDGGGGAAGPAGWLFGDGGAGGNGGAAAAGGAGGQAGGGGGNG
MSMEG_0868|M.smegmatis_MC2_155 DGHRGGKGGDGGEALIRATVIGSNASGTATGGDGGNGGTLGATNGTGGAA
TH_3810|M.thermoresistible__bu --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 --------------------------------------------------
MAV_4827|M.avium_104 Q-------------------------------------------------
MLBr_01556|M.leprae_Br4923 EGADPAKIRGQLTEYGLVAEDFGGDTMFIDISAKVGTNIEALLEAVLLTA
Mflv_5091|M.gilvum_PYR-GCK ----------------------GGTGGQGGTGGTGGQGGTGGTGGTGGTG
Mvan_1264|M.vanbaalenii_PYR-1 ----------------------GGTGGTGGTGGTGGQGGTGGTGGTGGTG
MUL_3990|M.ulcerans_Agy99 --------------------------------------------------
MMAR_4127|M.marinum_M --------------------------------------------------
Mb1121|M.bovis_AF2122/97 GNGGNGGNGGNGGNGATGGWLYGNGGA-GGQGATAGAGGAGANGVSSTNG
Rv1091|M.tuberculosis_H37Rv GNGGNGGNGGNGGNGATGGWLYGNGGA-GGQGATAGAGGAGANGVSSTNG
MSMEG_0868|M.smegmatis_MC2_155 TIVAYNVVQANPQASGTATDGHGGSGINGGHGGNGGQGTIEANGPSAVAS
TH_3810|M.thermoresistible__bu --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 --------------------------------GVLNTGVSGAIGGSSHVG
MAV_4827|M.avium_104 --------------------------------------------------
MLBr_01556|M.leprae_Br4923 DAALDLRANSGMEAQGVAIEAHLDRGRGPVATVLVQRGTLRIGDSVVAGD
Mflv_5091|M.gilvum_PYR-GCK G----------TGGAGGDGGLGGLGGFGGSGGTGGQGGLGGPGGSTG---
Mvan_1264|M.vanbaalenii_PYR-1 G----------TGGAGGDGGLGGLGGFGGVGGTGGQGGQGGPGGSTG---
MUL_3990|M.ulcerans_Agy99 --------------------------------------------------
MMAR_4127|M.marinum_M --------------------------------------------------
Mb1121|M.bovis_AF2122/97 G---GNGGIGGTGGSGGAGGNAGLLGVGGAGGHGASGGAGDRGGAGGTGF
Rv1091|M.tuberculosis_H37Rv GGTGGNGGIGGTGGSGGAGGNAGLLGVGGAGGHGASGGAGDRGGAGGTGF
MSMEG_0868|M.smegmatis_MC2_155 G--------IGAGGNGGDGIDGGLGGNGGDGVVNTTANAANPGSATGTAT
TH_3810|M.thermoresistible__bu --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 G-----------------------------AINESLGGSGSVGGSTAVGG
MAV_4827|M.avium_104 -----------------------------LLAPPRLSVPQPVQPPVRVPQ
MLBr_01556|M.leprae_Br4923 AYGRVRRMVDEHGVDIEAALPSSPVQVIGFTSVPGAGDNFLVVDEDRIAR
Mflv_5091|M.gilvum_PYR-GCK --GAGGAGGQAGTAGKGGLFG-----------GSGSAGKAGATGAAGASG
Mvan_1264|M.vanbaalenii_PYR-1 --GAGGAGGQAGVAGKGGLFG-----------GSGSAGTAGVTGASGASG
MUL_3990|M.ulcerans_Agy99 --------------GNDGG-------------GGAG--------------
MMAR_4127|M.marinum_M --------------GNGGG-------------GGAGGLLVGAGGAGGAGG
Mb1121|M.bovis_AF2122/97 ISSDGGAGGDGGDGGNGGA-------------GGTGGLLFGAGGNGGPGG
Rv1091|M.tuberculosis_H37Rv ISSDGGAGGDGGDGGNGGA-------------GGTGGLLFGAGGNGGPGG
MSMEG_0868|M.smegmatis_MC2_155 GGDGGKATGTASQGGNGGPSWVQSGYGSTLGGNATGTATAGKGGEASNGG
TH_3810|M.thermoresistible__bu --------------GRGXX-------------------------------
MAB_4284c|M.abscessus_ATCC_199 GAHTGVGGGVSTGVGVGSHVG------------GGISESLGGSGSVGGST
MAV_4827|M.avium_104 PPSPPQVGGTVPQSPPQHQTP----------PGEGTPPKPDGPGNYGGGH
MLBr_01556|M.leprae_Br4923 QIADRRSARKRNALAARSRKR-ISLEDLDSALKETSQLNLILKGDNAGTV
Mflv_5091|M.gilvum_PYR-GCK GKGAQGATGAQGATGAQGATGATGAAGKAGATGAAGAAGAAGSAG-----
Mvan_1264|M.vanbaalenii_PYR-1 GKGAQGATGAQGATGAQGATGATGASGAQGSAGSAGSAGVAGSAG-----
MUL_3990|M.ulcerans_Agy99 --------------------------------------------------
MMAR_4127|M.marinum_M DG--------------------GLHLSSFVGPGGSGGDGGAGGTG-----
Mb1121|M.bovis_AF2122/97 SGGAADIGGNGGAGNGGGTDGNGGNGGSGGGAGSGGDGGGAGGNG-----
Rv1091|M.tuberculosis_H37Rv SGGAADIGGNGGAGNGGGTDGNGGNGGSGGGAGSGGDGGGAGGNG-----
MSMEG_0868|M.smegmatis_MC2_155 VAGNGGNALVMAAGTTGVATGNTATGGDGGAATTAGATGGAGGFSNIAAI
TH_3810|M.thermoresistible__bu --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 AVGGGAHTGVGGGVSTGVGVGSHVGGGISESLGGSGSVGGSTAVG-----
MAV_4827|M.avium_104 VPTPGAGGSGGSGGGHVPTPGAGGSGGSGGGHVPTPGTGGPGGTG-----
MLBr_01556|M.leprae_Br4923 EALEEALMGIQVDDEVALRVIDRGVGGITETNVNLASASDAIIIG-----
Mflv_5091|M.gilvum_PYR-GCK -------TTGAQGSAGTNGANGANGSQGAAG----------KAGATGTTG
Mvan_1264|M.vanbaalenii_PYR-1 -------TTGAQGSAGTNGANGANGSQGAAG----------KAGATGTTG
MUL_3990|M.ulcerans_Agy99 -------------------GSGGNGFG-----------------------
MMAR_4127|M.marinum_M ------GWLYGDGGGGGSGGSGANGFG-----------------------
Mb1121|M.bovis_AF2122/97 ------AWLFGNGGAGGGGGKGGNGAGGGLGGGSFGLPGLNGSGGDGGDG
Rv1091|M.tuberculosis_H37Rv ------AWLFGNGGAGGGGGKGGNGAGGGLGGGSFGLPGLNGSGGDGGDG
MSMEG_0868|M.smegmatis_MC2_155 HGAITDSTAISGHGGAGNGGNGGKGADGWVQAYDPAGPVGSKIANSSAVA
TH_3810|M.thermoresistible__bu ----------XXGGGVGAAVRSGNGVFS----------------------
MAB_4284c|M.abscessus_ATCC_199 ---------GGAHTGVGGGVNTGVGVGSHVG--------------GGISE
MAV_4827|M.avium_104 ------------GSGGGHVPTPGAGTPGGSG-------------------
MLBr_01556|M.leprae_Br4923 --------FNVRAEGKATELASREGVEIRYYLVIYQAIDDIEKALRGMLK
*
Mflv_5091|M.gilvum_PYR-GCK ATGAAG-----EDGDAGSGGSGINGGAGGAGG--------AGGEGGEGGD
Mvan_1264|M.vanbaalenii_PYR-1 ATGAAG-----DAGDPGSEAVDINGGAGGAGG--------AGGEGGEGGA
MUL_3990|M.ulcerans_Agy99 ----------------------------TIGG--------TGGSGGRGGD
MMAR_4127|M.marinum_M ----------------------------TIGG--------TGGSGGRGGD
Mb1121|M.bovis_AF2122/97 GNGAPGGVLYGNGGAGGQGSSGGIGGPGATGG--------AGGKGGDGGD
Rv1091|M.tuberculosis_H37Rv GNGAPGGVLYGNGGAGGQGSSGGIGGPGATGG--------AGGKGGDGGD
MSMEG_0868|M.smegmatis_MC2_155 GNGGDGGVNGTGGASGGDGGNGGNTSVWKSGGQTADGEHNTGGNGGNGGD
TH_3810|M.thermoresistible__bu ------------------------------GG---------GGTPSAGFG
MAB_4284c|M.abscessus_ATCC_199 SLGGSGSVGGSTAVGGGAHTSAINDALGGSGS--------VGGSTAVGGG
MAV_4827|M.avium_104 --------------GGHLPFPGAGSTPGGSGG---------GHLPTPGAG
MLBr_01556|M.leprae_Br4923 PIYEEN-----QLGRAEIRALFRSSKVGIIAG------CIISSGVVRRNA
.. .
Mflv_5091|M.gilvum_PYR-GCK GGKGGAGA---EGGAGGGGGAGGSGAGGAGGAGGSGGSGGSGGSGGSGGA
Mvan_1264|M.vanbaalenii_PYR-1 GGAGGDGS---EGGAGGSGGAGGSGTGGAGGAGGSGGSGGSGGAGGSGGA
MUL_3990|M.ulcerans_Agy99 ARLIG------NGGDGGAGAPGGNSAPP--GDGGVGGAGG--TLSGTPGA
MMAR_4127|M.marinum_M ARLIG------NGGDGGAGAPGGNSAPP--GDGGVGGAGG--TLSGTPGA
Mb1121|M.bovis_AF2122/97 AQLIGDGG---NGGNGGAGGTGGTPGPG--GPGGSGGLGG--LLFGQTGT
Rv1091|M.tuberculosis_H37Rv AQLIGDGG---NGGNGGAGGTGGTPGPG--GPGGSGGLGG--LLFGQTGT
MSMEG_0868|M.smegmatis_MC2_155 GSEPGPGGNG-AGGAGGNGGTGGTTAGGS-GNGGNGGNGGNGGADGTPGT
TH_3810|M.thermoresistible__bu VPTTIQFP---AGSCTSRAVSREGIMPSSRAASARAGAACASSTSRSRRS
MAB_4284c|M.abscessus_ATCC_199 AHTSAINESMNSSINASHSSSMNESFGSSMGSHGAAGTGFEAQGHAQGHA
MAV_4827|M.avium_104 TPGGGLGGFGGGHAPAPGGGLGGGGGHAPAPGGGLGGFGGGHSGGGLGGL
MLBr_01556|M.leprae_Br4923 KVRLLRDNIVVTDNLTVTSLRREKDDVTEVREGFECGMTLGYSDIKEGDV
. *
Mflv_5091|M.gilvum_PYR-GCK AGDSDD--------
Mvan_1264|M.vanbaalenii_PYR-1 AGDSD---------
MUL_3990|M.ulcerans_Agy99 TGALG---------
MMAR_4127|M.marinum_M TGASG---------
Mb1121|M.bovis_AF2122/97 AGVSP---------
Rv1091|M.tuberculosis_H37Rv AGVSP---------
MSMEG_0868|M.smegmatis_MC2_155 AGTTGANNP-----
TH_3810|M.thermoresistible__bu FCCSRA--------
MAB_4284c|M.abscessus_ATCC_199 SETAHTTLPGAEHH
MAV_4827|M.avium_104 GGGHK---------
MLBr_01556|M.leprae_Br4923 IESYELVEKQRA--