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SYFIAVPDELALAATELDSIGAALSVANVAAALPTTGILAAGADDVSTAIAALFAGHAQAYQALSTAAST FHTQFVRALNLSGGAYAAADAANASPLQTLEQDLLGVLNAPTQALLGRPLIGDGADGTAPGQGGGAGGLL YGNGGSGAAGTNTGVAGGAGGDAGLIGNGGSGGAGGGGAAGGAGGNGGWLFGAGGNGGFGGAATGLGPGG AGGAGGHGGWLYGSGGTGGDGGFAKGGNGGAGGAGGDAGLLGAGGSGGTGGAGATSGPASSHFAGGAGGA GGHGGLLYGDGGTGGFGGDGGVGGAGGAGGGGGAAGLVGAGGAGGNGGAGLGILGEAGGNGGGGGAGGLL VGAGGAGGAGGDGGLHLSSFVGPGGSGGDGGAGGTGGWLYGDGGGGGSGGSGANGFGTIGGTGGSGGRGG DARLIGNGGDGGAGAPGGNSAPPGDGGVGGAGGTLSGTPGATGASG*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. marinum M | MMAR_4127 | - | - | 100% (467) | PE-PGRS family protein |
| M. marinum M | MMAR_5321 | - | e-148 | 54.56% (526) | PE-PGRS family protein |
| M. marinum M | MMAR_4377 | - | e-147 | 55.95% (529) | PE-PGRS family protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3420 | PE_PGRS52 | 1e-143 | 54.10% (549) | PE-PGRS family protein |
| M. gilvum PYR-GCK | Mflv_5091 | - | 6e-83 | 49.86% (359) | triple helix repeat-containing collagen |
| M. tuberculosis H37Rv | Rv3388 | PE_PGRS52 | 1e-149 | 53.96% (556) | PE-PGRS family protein |
| M. leprae Br4923 | MLBr_01183 | - | 1e-12 | 39.78% (93) | hypothetical protein MLBr_01183 |
| M. abscessus ATCC 19977 | MAB_4284c | - | 3e-41 | 38.10% (357) | hypothetical protein MAB_4284c |
| M. avium 104 | MAV_4827 | - | 8e-23 | 45.12% (164) | hypothetical protein MAV_4827 |
| M. smegmatis MC2 155 | MSMEG_0868 | - | 5e-70 | 40.19% (428) | hypothetical protein MSMEG_0868 |
| M. thermoresistible (build 8) | TH_3810 | - | 5e-39 | 41.78% (292) | PUTATIVE - |
| M. ulcerans Agy99 | MUL_3990 | - | 0.0 | 84.27% (426) | PE-PGRS family protein |
| M. vanbaalenii PYR-1 | Mvan_1264 | - | 9e-88 | 44.05% (504) | triple helix repeat-containing collagen |
CLUSTAL 2.0.9 multiple sequence alignment
MMAR_4127|M.marinum_M --------------------------------------------------
MUL_3990|M.ulcerans_Agy99 --------------------------------------------------
Mb3420|M.bovis_AF2122/97 --------------------------------------------------
Rv3388|M.tuberculosis_H37Rv --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_1264|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_0868|M.smegmatis_MC2_155 MHERLRERAGGVRKTLSDFAEGAGLKPSDTDDTRSPLRKPKFPAALAPES
TH_3810|M.thermoresistible__bu --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 --------------------------------------------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_4827|M.avium_104 --------------------------------------------------
MMAR_4127|M.marinum_M --------------------------------------------------
MUL_3990|M.ulcerans_Agy99 --------------------------------------------------
Mb3420|M.bovis_AF2122/97 --------------------------------------------------
Rv3388|M.tuberculosis_H37Rv --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_1264|M.vanbaalenii_PYR-1 -------------------MMFLAPPGGPGPISAAIQLTSTGSEATEP--
MSMEG_0868|M.smegmatis_MC2_155 PLPDLKPRWERPTTAPDSETPSITQPQGRDTAADPAEQQATSTNTTDQPT
TH_3810|M.thermoresistible__bu --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 --------------------------------------------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_4827|M.avium_104 --------------------------------------------------
MMAR_4127|M.marinum_M ---------------------------------------MSYFIAVP---
MUL_3990|M.ulcerans_Agy99 ---------------------------------------MSYFIAVP---
Mb3420|M.bovis_AF2122/97 ---------------------------------------MSFVIANP---
Rv3388|M.tuberculosis_H37Rv ---------------------------------------MSFVIANP---
Mflv_5091|M.gilvum_PYR-GCK --------------------------------------MVTFGGGATPTP
Mvan_1264|M.vanbaalenii_PYR-1 ------------------------------------WYVVSFGGSGAPTP
MSMEG_0868|M.smegmatis_MC2_155 SDSLGAQPTAQVARQVQAPATDPAPAAPSLRPISGLLSVVTLGTTLIPNA
TH_3810|M.thermoresistible__bu --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 ------------------------------------MSIIDFILNLFRDP
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_4827|M.avium_104 -------------------------------------MNIVLGVSMAP--
MMAR_4127|M.marinum_M ----------------------------------------DELALAATEL
MUL_3990|M.ulcerans_Agy99 ----------------------------------------DELALAATEL
Mb3420|M.bovis_AF2122/97 ----------------------------------------EMLAAAATDL
Rv3388|M.tuberculosis_H37Rv ----------------------------------------EMLAAAATDL
Mflv_5091|M.gilvum_PYR-GCK ----------------------------------------TSLGAAAVDL
Mvan_1264|M.vanbaalenii_PYR-1 ----------------------------------------NNLAASLVDL
MSMEG_0868|M.smegmatis_MC2_155 PTEPADMPGVWAVMAWARRQPMYSDPAMRTTVNPQAQLPVPTVASAVLDP
TH_3810|M.thermoresistible__bu --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 ----------------------------------------VEAASYVADP
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_4827|M.avium_104 ----------------------------------------SSIQMVVLEG
MMAR_4127|M.marinum_M DSIG----------------------------------------AALSVA
MUL_3990|M.ulcerans_Agy99 DSIG----------------------------------------AALSVA
Mb3420|M.bovis_AF2122/97 AGIR----------------------------------------SAISAA
Rv3388|M.tuberculosis_H37Rv AGIR----------------------------------------SAISAA
Mflv_5091|M.gilvum_PYR-GCK S------------------------GTSCG----------LICNGQDGTG
Mvan_1264|M.vanbaalenii_PYR-1 S------------------------GTSCG----------LICNGQDGTG
MSMEG_0868|M.smegmatis_MC2_155 TQIVNWLIYQPLHAAGQQFWVVSPIGSTLGGVINTISGQYLIGNGINGTA
TH_3810|M.thermoresistible__bu --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 EAA-------------------------------------LANAGLSAVS
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_4827|M.avium_104 EYADG---------------------------------------ATVEED
MMAR_4127|M.marinum_M NVAAALPTTGILAAGADDVSTAIAALFAGHAQAYQALSTAASTFHTQFVR
MUL_3990|M.ulcerans_Agy99 NVAAALPTTGILAAGADDVSTAIA----------------ASTFHTQFVR
Mb3420|M.bovis_AF2122/97 TAAAAAPTIQVAAAGADEVSLAISALFGQHAQAYQALSAQATIFHDQFVQ
Rv3388|M.tuberculosis_H37Rv TAAAAAPTIQVAAAGADEVSLAISALFGQHAQAYQALSAQATIFHDQFVQ
Mflv_5091|M.gilvum_PYR-GCK QN-----GGILFGNGGSGWNSDVVGMDGGNGGNGGLFGGNGGNGGNGLGG
Mvan_1264|M.vanbaalenii_PYR-1 QN-----GGILFGNGGSGWNSEIAGVSGGNGGNAGLFGGNGGNGGNGLGS
MSMEG_0868|M.smegmatis_MC2_155 DNPNGGTGGLLFGDGGHGYDGSAAGLAGGNGGNAGLFG-NGGNGGVGWAG
TH_3810|M.thermoresistible__bu ------------------------------------------------VD
MAB_4284c|M.abscessus_ATCC_199 AAQVGAVMPVVAESVASNYGYQSQWVNTGN----PIHDLSGNLQNYYAAQ
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_4827|M.avium_104 AIDVTGADDAATASAPDRVISAILGTREGAADAGLQLSSIGVTWTDQLEA
MMAR_4127|M.marinum_M ALNLSGGAYAAADAANASPLQTLEQDLLGVLNAPTQALLGRPLIGDGADG
MUL_3990|M.ulcerans_Agy99 ALNLSGGAYAAADVANASPLQTLEQDLLGVLNAPTQALLGGPLIGDGADG
Mb3420|M.bovis_AF2122/97 ALTSGGNLYAAAES------HTVEQMVLNAINAPTQTLFGRPLIGDGANG
Rv3388|M.tuberculosis_H37Rv ALTSGGNLYAAAES------HTVEQMVLNAINAPTQTLFGRPLIGDGANG
Mflv_5091|M.gilvum_PYR-GCK GNGGNGGNAGAFALFGNGGNGGNGGVGVVGATGAVG--APGVAGATGATG
Mvan_1264|M.vanbaalenii_PYR-1 GDGGNGGDAGLFSLFGRGGNGGNGGVGIAGATGAVG--APGVAGATGATG
MSMEG_0868|M.smegmatis_MC2_155 LDGGNGGSGG--LLMGIGGAGGAGGVGADGTSAHVDGGTGGTGGTGGGTG
TH_3810|M.thermoresistible__bu GDGGSGGRTGLFSKLSRGGDGGDGGLG-------------GNGGHGGGTG
MAB_4284c|M.abscessus_ATCC_199 PDGPSILSPSLLSPRDNDFLSHNDTDFASHNPIASGNQVMSPSGNVDSFN
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_4827|M.avium_104 AALRDALAARRIDNVMLVSAFLAAAALAQNVGGAMGYERTAVLLVEPDTA
MMAR_4127|M.marinum_M TAPGQGGGAGGLLYGNGGSGAAGTNTGVAGGAGGD---------------
MUL_3990|M.ulcerans_Agy99 TAPGQGGGAGGLLYGNGGSGAAGTNTGVAGGAGGA---------------
Mb3420|M.bovis_AF2122/97 TAENPDGQNGGLLFGNGGNGFTQTTAGVAGGNGGS---------------
Rv3388|M.tuberculosis_H37Rv TAENPDGQNGGLLFGNGGNGFTQTTAGVAGGNGGS---------------
Mflv_5091|M.gilvum_PYR-GCK VTSGVVGGNGEDAVGYGATGAAGAAGAAGAAGAAG--------------A
Mvan_1264|M.vanbaalenii_PYR-1 VTSNVTGGNGADAVGYGATGAAGAAGAAGAAGKAG--------------A
MSMEG_0868|M.smegmatis_MC2_155 GTGGIGGTGGGLFGLLGHSGSTGAAGAAGNGGDGGNGGFGYVLIAGPNVT
TH_3810|M.thermoresistible__bu IIS--------------------LLSLAGNGGNGG---------------
MAB_4284c|M.abscessus_ATCC_199 RGPLLDLSFGDLQFGNRDTTAIGDGAVAVGGSNSG---------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_4827|M.avium_104 TLAVVETSDGSIPDVYKQQIRAESYGDAAGQLSAMVAG------------
MMAR_4127|M.marinum_M --------------------------------------------------
MUL_3990|M.ulcerans_Agy99 --------------------------------------------------
Mb3420|M.bovis_AF2122/97 --------------------------------------------------
Rv3388|M.tuberculosis_H37Rv --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK VGSAGAAGEAGETGTWG--NAGLPGKAGDAGGAG----AVGAAG------
Mvan_1264|M.vanbaalenii_PYR-1 VGSAGTAGSAGAPGVWG--NAGLPGAAGAAGGAG----AIGTAG------
MSMEG_0868|M.smegmatis_MC2_155 VGSETRGGTGGAGGTGGQSTAAGPGKGGGGGGGGGGAILIGANGGTVDGH
TH_3810|M.thermoresistible__bu --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 --------------------------------------------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_4827|M.avium_104 --------------------------------------------------
MMAR_4127|M.marinum_M -----------AGLIGNGGSGGAGGGG-----------AAGGAGGNGG--
MUL_3990|M.ulcerans_Agy99 -----------AGLVGNGGSGGAGGGG-----------AAGGAGGNGG--
Mb3420|M.bovis_AF2122/97 -----------AGLIGNGGAGGIGGAGT-------GTGGHGGAGGAGGRA
Rv3388|M.tuberculosis_H37Rv -----------AGLIGNGGAGGGGGAG-----------AAGGLGGNGG--
Mflv_5091|M.gilvum_PYR-GCK -AAGTVGTAGATGGTGTGANGGAGGVG-----GVGGTGAAGAAGGAGGLG
Mvan_1264|M.vanbaalenii_PYR-1 -VAGAAGTAGATGGTGVGGNGGAGQAG-----GIGGTGAAGAAGQAGTAG
MSMEG_0868|M.smegmatis_MC2_155 AIGGNGGNGGNGSTTAAGGNGGTGGTGRVIAEGTGSTAEGTATGGDGGHS
TH_3810|M.thermoresistible__bu --------NGYRTTDNNALDGGHGGNG-----------------GNVGFF
MAB_4284c|M.abscessus_ATCC_199 --------PIASGQGSTAVNGDVRDSN-----IINADHGSNVGVDQSQTR
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_4827|M.avium_104 ----------LEKLESLPGGLLLVGSG--------VDVAPLKQVLQTTTF
MMAR_4127|M.marinum_M WLFGAG---GNGGFG--------------------GAATGL---------
MUL_3990|M.ulcerans_Agy99 WLFGAG---GNGGFG--------------------GAATGL---------
Mb3420|M.bovis_AF2122/97 WLWGTG---GAGGAG--------------------AAAIGN-----AVTP
Rv3388|M.tuberculosis_H37Rv WLYGNG---GAGGIG--------------------GAGTGTGGHGGAGGA
Mflv_5091|M.gilvum_PYR-GCK ETGTTG---GAGGVG--------------------GQGTAGGTGGVGGIG
Mvan_1264|M.vanbaalenii_PYR-1 ETGVTG---GVGGIG--------------------GQGTEGGTGGVGGVG
MSMEG_0868|M.smegmatis_MC2_155 TGTGIG---GNGGIGSVYAYGNNGAVSGTATGGRGGDGIDGGTGGAGGMG
TH_3810|M.thermoresistible__bu SLFNLG---GAGGWG--------------------GSGVDG---------
MAB_4284c|M.abscessus_ATCC_199 VGGDYTNVSGHG-----------------------SADIDKSVTVVDDHS
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_4827|M.avium_104 LDVSVAEEPETALAR--------------------GAALAAAN-------
MMAR_4127|M.marinum_M -------------GPGGAGG------------------------------
MUL_3990|M.ulcerans_Agy99 -------------GPGGAGG------------------------------
Mb3420|M.bovis_AF2122/97 G------------GAGGAGG------------------------------
Rv3388|M.tuberculosis_H37Rv GGR------AWLWGTGGAGG------------------------------
Mflv_5091|M.gilvum_PYR-GCK GAG----------STGAVGG-------VGGKG----IQGGQG--------
Mvan_1264|M.vanbaalenii_PYR-1 GVG----------ATGGAGG-------VGGKG----IQGGQG--------
MSMEG_0868|M.smegmatis_MC2_155 EIYSGADGEATGISAGGDGGSATGADSLGGRGGTSWVQAGYGPTTGGKAS
TH_3810|M.thermoresistible__bu --------------VDVVGG------------------------------
MAB_4284c|M.abscessus_ATCC_199 QRN----------TTNINDS------------------------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_4827|M.avium_104 -------------APLFASS------------------------------
MMAR_4127|M.marinum_M --AGGHGGWLYGSGGTGGDGGFAKGGN-----------------------
MUL_3990|M.ulcerans_Agy99 --YGGHGGWLYGSGGTGGDGGFAKGGN-----------------------
Mb3420|M.bovis_AF2122/97 --AGGDGGWLFGDGGAGGTGGNGGSGFN----------------SLTSSV
Rv3388|M.tuberculosis_H37Rv --AGGDGGWLFGDGGAGGTGGNGGSGFN----------------SLTSSV
Mflv_5091|M.gilvum_PYR-GCK -----LQGGKGGDGGAGGKGGDADSMGS------------------AGAT
Mvan_1264|M.vanbaalenii_PYR-1 -----LQGGQGGDGGTGGTGGDATSMGE------------------AGAT
MSMEG_0868|M.smegmatis_MC2_155 GTAKAGHGGKASDGGKGGNGGDALVMAAGATGVATGNTAIGGNGGAASAN
TH_3810|M.thermoresistible__bu ----------NPDGGTPG------------------------------AH
MAB_4284c|M.abscessus_ATCC_199 -----FNTDRSTNIGSGNTTNTEIGSHN------------------QANI
MLBr_01183|M.leprae_Br4923 -----------------------------------------------MPL
MAV_4827|M.avium_104 ----TAALAYAQDPGTGAVDQYSLPDYLY--------------------V
MMAR_4127|M.marinum_M GGAGGAGGDAGLLG------------------------------------
MUL_3990|M.ulcerans_Agy99 GGAGGAGGDAGLLG------------------------------------
Mb3420|M.bovis_AF2122/97 GGAGGAGGHAGLFG------------------------------------
Rv3388|M.tuberculosis_H37Rv GGAGGAGGHAGLFG------------------------------------
Mflv_5091|M.gilvum_PYR-GCK GGKGGNGGNGGRGGLFG---------------KGGNAGNGAD--------
Mvan_1264|M.vanbaalenii_PYR-1 GGKGGNGGNGGRGSLFG---------------RGGNAGNGGN--------
MSMEG_0868|M.smegmatis_MC2_155 GAVGGNGGFTNIAAIHGSITDSSATSGHGGAAQGGNGGNGGNGWVQAYDP
TH_3810|M.thermoresistible__bu GESHTPGVYTDRQ-------------------------------------
MAB_4284c|M.abscessus_ATCC_199 GTSTSAGGSAAVGGNAG---------------------------------
MLBr_01183|M.leprae_Br4923 FLNAEPQALTAAAN------------------------------------
MAV_4827|M.avium_104 PVDPEPGDDELAYS------------------------------------
MMAR_4127|M.marinum_M ----------------AGGSGGTGGAG---ATSGPASSHF----------
MUL_3990|M.ulcerans_Agy99 ----------------AGGSGGTGGAG---ATSGPASSHF----------
Mb3420|M.bovis_AF2122/97 ----------------AGGTGGTGGIGGQNTETGPAASN-----------
Rv3388|M.tuberculosis_H37Rv ----------------AGGTGGTGGIGGQNTETGPAASN-----------
Mflv_5091|M.gilvum_PYR-GCK --------------GGTGGAGGAGGTGG-TGGAGGTGG------------
Mvan_1264|M.vanbaalenii_PYR-1 --------------GGTGGNGGNGGTGG-TGGNGGTGG------------
MSMEG_0868|M.smegmatis_MC2_155 NGPAGTTIDKGKAAGGNGGDGGFNGTGGATGGRGGDGAGASVWKANGQHS
TH_3810|M.thermoresistible__bu ------------------GEDGEDGTGTGIGGRGGNGG------------
MAB_4284c|M.abscessus_ATCC_199 ----------------LAGNAGLAGNAGLAGNAGLAGN------------
MLBr_01183|M.leprae_Br4923 ------------------TLEGLSAATVASNAAAAQLT------------
MAV_4827|M.avium_104 ----------------AVGEEDAESPTVVIEKLFLPEDS-----------
. .
MMAR_4127|M.marinum_M ----AGGAGGAGGHGGLLYGDGGTGGFGGDGG---------VGGAGGAGG
MUL_3990|M.ulcerans_Agy99 ----AGGAGGAGGHGGLLYGDGETGGFGGDGG---------VGGAGGAGG
Mb3420|M.bovis_AF2122/97 -----GGAGGAGGGGGYLVGDGGAGGTGGAGGKNSSGGATLTGGTGGTGG
Rv3388|M.tuberculosis_H37Rv -----GGAGGAGGGGGYLVGDGGAGGTGGAGGKNSSGGATLTGGTGGTGG
Mflv_5091|M.gilvum_PYR-GCK -----TGGTGGIGGAGSTGGTGGTGGTGGTGGTGGTG---GTGGTGGTGG
Mvan_1264|M.vanbaalenii_PYR-1 -----TGGTGGIGGAGSTGGTGGTGGTGGTGGTGGTG---GTGGTGGTGG
MSMEG_0868|M.smegmatis_MC2_155 TGQTDTGGNGGRGGDGGTFVNAGANGNGGAGGAGGVSE--GEGGTGGHGG
TH_3810|M.thermoresistible__bu ----SSSGTHPMAEDG--------EHVKALDGRPGLD-----GGNGSHGG
MAB_4284c|M.abscessus_ATCC_199 ---AGLAGNAGLAGNAGLAGNAGLAGNAGLAGNAGLAGNAGLAGNAGLAG
MLBr_01183|M.leprae_Br4923 -----TEIAPPAADDVSILLAHFFSGHG--------------RQYQAHAS
MAV_4827|M.avium_104 -----EPRRRPVLLVGSGLAVVGISAVLALEIALAIG----IRTTGTVAL
.
MMAR_4127|M.marinum_M GGGAAG-LVGAGGAGGNGG-----AGLGILGEAGGNGGGGGAGGLLV---
MUL_3990|M.ulcerans_Agy99 GGGAAG-LVGAGGAGGNGG-----AGLGILGEAGGNDGGGGAG-------
Mb3420|M.bovis_AF2122/97 AGGAAGWLYGSGGAGGAG---GLNNAGGATGGTGGTGGAGGSGAWLY---
Rv3388|M.tuberculosis_H37Rv AGGAAGWLYGSGGAGGAGGAGGLNNAGGATGGTGGTGGAGGSGAWLY---
Mflv_5091|M.gilvum_PYR-GCK TGGKGG-TGGTGGAGGTG----------GDGGTGGTGGTGGTG-------
Mvan_1264|M.vanbaalenii_PYR-1 TGGKGG-TGGTGGDGGTG----------GTGGTGGTGGTGGTG-------
MSMEG_0868|M.smegmatis_MC2_155 DGGRGG-DGALGGNGGTGGV------GLGNGGKGGNGGNGGNGGTYVDPS
TH_3810|M.thermoresistible__bu NGGHGG-RGGFLGIGGSG-------------GWGGHGGNGGD--------
MAB_4284c|M.abscessus_ATCC_199 NAGLAG-NAGLAGNAGLAG----------NAGLAGNAGLAGNAG------
MLBr_01183|M.leprae_Br4923 QGATNH-QDLIQSLLTSS------------SAYAGTETANHDSL------
MAV_4827|M.avium_104 QPTPNQHLIVPTEQAPAPP---------PVQASAPQPKISVPEP------
.
MMAR_4127|M.marinum_M --GAGGAGGAGGDGGLHLSS------------------------------
MUL_3990|M.ulcerans_Agy99 --------------------------------------------------
Mb3420|M.bovis_AF2122/97 --GNGGAAGAGGNGGNNTSAGTGGVGASGGTGGNAGLIGAGGHGGAGGAG
Rv3388|M.tuberculosis_H37Rv --GNGGAAGAGGNGGNNTSAGTGGVGASGGTGGNAGLIGAGGHGGAGGAG
Mflv_5091|M.gilvum_PYR-GCK --GTGGTGGTGGAG-----------DGTGGTGGTGG----TGGQGGQGGQ
Mvan_1264|M.vanbaalenii_PYR-1 --GTGGTGGTGGAG-----------DGLGGTGGTGG----TGGFGGQGGQ
MSMEG_0868|M.smegmatis_MC2_155 HTGAGGNGGNGGAGRIRVNNGTATGTATGGNGGNGGNGDADGHRGGKGGD
TH_3810|M.thermoresistible__bu ---TDADGGNGGDG---------------GNGGSAG--------------
MAB_4284c|M.abscessus_ATCC_199 --LAGNAGLAGNAG-------------LAGNAGLAG--------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_4827|M.avium_104 --VAAPKPLSPPVAAP----------------------------------
MMAR_4127|M.marinum_M ----------------------FVGPGGSGGDGGAGG-------------
MUL_3990|M.ulcerans_Agy99 --------------------------------------------------
Mb3420|M.bovis_AF2122/97 GN-----------------QTGGVGNGGAGGNGGAGG-------------
Rv3388|M.tuberculosis_H37Rv GN-----------------QTGGVGNGGAGGNGGAGG-------------
Mflv_5091|M.gilvum_PYR-GCK GG-----------------TGGTGGQGG-LGGGGGTG-------------
Mvan_1264|M.vanbaalenii_PYR-1 GG-----------------TGGTGGQGG-LGGVGGTG-------------
MSMEG_0868|M.smegmatis_MC2_155 GGEALIRATVIGSNASGTATGGDGGNGGTLGATNGTGGAATIVAYNVVQA
TH_3810|M.thermoresistible__bu -------------------RGGTGGLRGVFGINGGNG-------------
MAB_4284c|M.abscessus_ATCC_199 -------------------NAAVAGNAAVAGNAAVAG-------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_4827|M.avium_104 ------------------LPAAPPPAAPPLPEAPPIP-------------
MMAR_4127|M.marinum_M ----------TGGWLYGDGGGGGSGGSGAN------------------GF
MUL_3990|M.ulcerans_Agy99 -------------------------GSGGN------------------GF
Mb3420|M.bovis_AF2122/97 ----------AGGQLYGNGGDGGNGGAGGANIAG--------------GN
Rv3388|M.tuberculosis_H37Rv ----------AGGQLYGNGGDGGNGGAGGANIAG--------------GN
Mflv_5091|M.gilvum_PYR-GCK ----------GQGGTGGTGGQGGTGGTGGTGGTG--------GTGGAGGD
Mvan_1264|M.vanbaalenii_PYR-1 ----------GTGGTGGTGGQGGTGGTGGTGGTG--------GTGGAGGD
MSMEG_0868|M.smegmatis_MC2_155 NPQASGTATDGHGGSGINGGHGGNGGQGTIEANGPSAVASGIGAGGNGGD
TH_3810|M.thermoresistible__bu -----------RAGLGGRGXXXXGGGVGAAVRSG---------------N
MAB_4284c|M.abscessus_ATCC_199 -----------NAAVGGVLNTGVSGAIGGSSHVG---------GAINESL
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_4827|M.avium_104 ----------AAPPVVPVPVVVPPVPVPVPVRIP--------------VP
MMAR_4127|M.marinum_M GTIGGTGGSGGRGGDARLIGNGGDGGAGAPGGNSAPP-------------
MUL_3990|M.ulcerans_Agy99 GTIGGTGGSGGRGGDARLIGNGGDGGAGAPGGNSAPP-------------
Mb3420|M.bovis_AF2122/97 GSDGGAAGHGGAGGSARLIGAGGHGGDGGAGGNTAGRRAD----------
Rv3388|M.tuberculosis_H37Rv GSDGGAAGHGGAGGSARLIGAGGHGGDGGAGGNTAGRRAD----------
Mflv_5091|M.gilvum_PYR-GCK GGLGGLGGFGGSGGTGGQGGLGGPGGSTGGAGGAGG--QAGTAGKGGLFG
Mvan_1264|M.vanbaalenii_PYR-1 GGLGGLGGFGGVGGTGGQGGQGGPGGSTGGAGGAGG--QAGVAGKGGLFG
MSMEG_0868|M.smegmatis_MC2_155 GIDGGLGGNGGDGVVNTTANAANPGSATGTATGGDGGKATGTASQGGNGG
TH_3810|M.thermoresistible__bu GVFSGGGGTPSAGFGVPTTIQFPAGSCTSRAVSREG--------------
MAB_4284c|M.abscessus_ATCC_199 GGSGSVGGSTAVGGGAHTGVGGGVSTGVGVGSHVGG--------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_4827|M.avium_104 DPVSPPQLLAPPRLSVPQPVQPPVRVPQPPSPPQVGG-------------
MMAR_4127|M.marinum_M ---------GDGGVGGAGGTLSGTPGA-----------------------
MUL_3990|M.ulcerans_Agy99 ---------GDGGVGGAGGTLSGTPGA-----------------------
Mb3420|M.bovis_AF2122/97 ---AIAGTGGDGGNGGNGGLLSGNAGAGGHGGAGGSS---------TATT
Rv3388|M.tuberculosis_H37Rv ---AIAGTGGDGGNGGNGGLLSGNAGAGGHGGAGGSS---------TATT
Mflv_5091|M.gilvum_PYR-GCK ----GSGSAGKAGATGAAGASGGKGAQGATGAQGATG------AQGATG-
Mvan_1264|M.vanbaalenii_PYR-1 ----GSGSAGTAGVTGASGASGGKGAQGATGAQGATG------AQGATG-
MSMEG_0868|M.smegmatis_MC2_155 PSWVQSGYGSTLGGNATGTATAGKGGEASNGGVAGNGGNALVMAAGTTGV
TH_3810|M.thermoresistible__bu ----------IMPSSRAASARAG---------------------------
MAB_4284c|M.abscessus_ATCC_199 ------GISESLGGSGSVGGSTAVGGGAHTGVGGGVS----------TGV
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_4827|M.avium_104 ---------TVPQSPPQHQTPPGEGTPPKPDGPGNYG-------------
MMAR_4127|M.marinum_M ------TGASG---------------------------------------
MUL_3990|M.ulcerans_Agy99 ------TGALG---------------------------------------
Mb3420|M.bovis_AF2122/97 TTGTPPTGATGGNGGNGGAGGTAGFTGSGGIGGNGGAGGTGGNAGVALSV
Rv3388|M.tuberculosis_H37Rv TTGTPPTGATGGNGGNGGAGGTAGFTGSGGIGGNGGAGGTGGNAGVALSV
Mflv_5091|M.gilvum_PYR-GCK ATGAAGKAGATGAAGAAGAAGSAG-----------TTGAQGSAGTNGA-N
Mvan_1264|M.vanbaalenii_PYR-1 ATGASGAQGSAGSAGSAGVAGSAG-----------TTGAQGSAGTNGA-N
MSMEG_0868|M.smegmatis_MC2_155 ATGNTATGGDGGAATTAGATGGAGGFSNIAAIHGAITDSTAISGHGGAGN
TH_3810|M.thermoresistible__bu AACASSTSRSRRSFCCSRA-------------------------------
MAB_4284c|M.abscessus_ATCC_199 GVGSHVGGGISESLGGSGSVGGSTAVG---------GGAHTGVGGGVNTG
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_4827|M.avium_104 -GGHVPTPGAGGSGGSGGGHVPTPG-----------AGGSGGSGGGHVPT
MMAR_4127|M.marinum_M --------------------------------------------------
MUL_3990|M.ulcerans_Agy99 --------------------------------------------------
Mb3420|M.bovis_AF2122/97 GSTGGLGGNGGSGGLGGGGGSLFGNGGAGGVGATGGNAGSGIGPASVGGN
Rv3388|M.tuberculosis_H37Rv GSTGGLGGNGGSGGLGGGGGSLFGNGGAGGVGATGGNGGSGIGPASVGGN
Mflv_5091|M.gilvum_PYR-GCK GANGSQGAAGKAGATGTTGATG--------AAGEDGDAGSGGSG-INGGA
Mvan_1264|M.vanbaalenii_PYR-1 GANGSQGAAGKAGATGTTGATG--------AAGDAGDPGSEAVD-INGGA
MSMEG_0868|M.smegmatis_MC2_155 GGNGGKGADGWVQAYDPAGPVGSKIANSSAVAGNGGDGGVNGTGGASGGD
TH_3810|M.thermoresistible__bu --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 VGVGSHVGGGISESLGGSGSVG-------GSTAVGGGAHTSAINDALGGS
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_4827|M.avium_104 PGTGGPGGTGGSGGGHVP------------TPGAGTPGGSGGGHLPFPGA
MMAR_4127|M.marinum_M --------------------------------------------------
MUL_3990|M.ulcerans_Agy99 --------------------------------------------------
Mb3420|M.bovis_AF2122/97 GGKGGVG--------AAGGLAGQIGNGGSGGSGGAGGNGGTGDTAGNGGN
Rv3388|M.tuberculosis_H37Rv GGKGGVG--------AAGGLAGQIGNGGSGGSGGAGGNGGTGDTAGNGGN
Mflv_5091|M.gilvum_PYR-GCK GGAGG-----------AGGEGGEGGDGGKGGAGAE--------GGAGGGG
Mvan_1264|M.vanbaalenii_PYR-1 GGAGG-----------AGGEGGEGGAGGAGGDGSE--------GGAGGSG
MSMEG_0868|M.smegmatis_MC2_155 GGNGGNTSVWKSGGQTADGEHNTGGNGGNGGDGSEPGPGGNGAGGAGGNG
TH_3810|M.thermoresistible__bu --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 GSVGG----------STAVGGGAHTSAINESMNSSINASHSSSMNESFGS
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_4827|M.avium_104 GSTPGGS---------GGGHLPTPGAGTPGGGLGGFGGGHAPAPGGGLGG
MMAR_4127|M.marinum_M --------------------------------------------------
MUL_3990|M.ulcerans_Agy99 --------------------------------------------------
Mb3420|M.bovis_AF2122/97 GGAGAVGGNAQLIGNGGNGGGGGNGGTGATPGTGGAGAAGGTGGTLFGAP
Rv3388|M.tuberculosis_H37Rv GGAGAVGGNAQLIGNGGNGGGGGNGGT-----------------------
Mflv_5091|M.gilvum_PYR-GCK GAGGSGAGGAG--GAGGSGGSGGSGGSGGSGGAAGDSDD-----------
Mvan_1264|M.vanbaalenii_PYR-1 GAGGSGTGGAG--GAGGSGGSGGSGGAGGSGGAAGDSD------------
MSMEG_0868|M.smegmatis_MC2_155 GTGGTTAGGSGNGGNGGNGGNGGADGTPGTAGTTGANNP-----------
TH_3810|M.thermoresistible__bu --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 SMGSHGAAGTGFEAQGHAQGHASETAHTTLPGAEHH--------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_4827|M.avium_104 GGGHAPAPGGGLGGFGGGHSGGGLGGLGGGHK------------------
MMAR_4127|M.marinum_M --------
MUL_3990|M.ulcerans_Agy99 --------
Mb3420|M.bovis_AF2122/97 GTTGADGT
Rv3388|M.tuberculosis_H37Rv ---GADGT
Mflv_5091|M.gilvum_PYR-GCK --------
Mvan_1264|M.vanbaalenii_PYR-1 --------
MSMEG_0868|M.smegmatis_MC2_155 --------
TH_3810|M.thermoresistible__bu --------
MAB_4284c|M.abscessus_ATCC_199 --------
MLBr_01183|M.leprae_Br4923 --------
MAV_4827|M.avium_104 --------