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MSYVLVTPEMVATAAADAAAIGSTVSAANAAAAIPTTAIATAAADDVSAAIAALFNAHAEQYQALSVRVA EFHESFTRALTAGSTAYATAEAANAGPLQPLLDLINAPTQALLARPLIGDGTNGAPGTGQAGGNGGLLVG NGGAGGLLFGQGGAGGANGLFEAAGSGGSGGAGGDGAPGDSGTAGGTGGTGSARGAGGTGGVGGANQFFG HAGDGGHGGTGGAGGTGGAGGSGVGSGLAGGTGGDGGVGGAAGRGGAADAGGPLVTPGHAGNTGTGGTGG TGGTGGNGDLHTDGGNGGTGGSGGAGIAGVGGGNGGHGTDGSAGVAGHGGGAGGAGGDAGDGGKGGDALD GGTAGTGGAGGNAGNGGGAGSGGKGTFDGGAGGAGGDGGKAGNGGAGGIDSNGQVADGGNGGDGGNGGDG SPVGAGGTGGIGTAGGAGGGGGAVSGRPGQNGSEGQPG
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. ulcerans Agy99 | MUL_3704 | - | - | 100% (458) | PE-PGRS family protein |
| M. ulcerans Agy99 | MUL_3318 | - | e-130 | 46.93% (586) | PE-PGRS family protein |
| M. ulcerans Agy99 | MUL_2354 | - | e-119 | 50.00% (500) | PE-PGRS family protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1849c | PE_PGRS33 | 1e-123 | 53.02% (513) | PE-PGRS family protein |
| M. gilvum PYR-GCK | Mflv_5091 | - | 2e-87 | 45.37% (454) | triple helix repeat-containing collagen |
| M. tuberculosis H37Rv | Rv1818c | PE_PGRS33 | 1e-123 | 53.06% (507) | PE-PGRS family protein |
| M. leprae Br4923 | MLBr_01183 | - | 5e-12 | 41.38% (87) | hypothetical protein MLBr_01183 |
| M. abscessus ATCC 19977 | MAB_4284c | - | 4e-42 | 34.90% (404) | hypothetical protein MAB_4284c |
| M. marinum M | MMAR_3758 | - | 0.0 | 61.54% (598) | PE-PGRS family protein |
| M. avium 104 | MAV_4827 | - | 2e-24 | 43.43% (175) | hypothetical protein MAV_4827 |
| M. smegmatis MC2 155 | MSMEG_0868 | - | 4e-61 | 39.35% (432) | hypothetical protein MSMEG_0868 |
| M. thermoresistible (build 8) | TH_3810 | - | 9e-44 | 41.87% (289) | PUTATIVE - |
| M. vanbaalenii PYR-1 | Mvan_1264 | - | 3e-87 | 44.07% (472) | triple helix repeat-containing collagen |
CLUSTAL 2.0.9 multiple sequence alignment
Mb1849c|M.bovis_AF2122/97 --------------------------------------------------
Rv1818c|M.tuberculosis_H37Rv --------------------------------------------------
MUL_3704|M.ulcerans_Agy99 --------------------------------------------------
MMAR_3758|M.marinum_M --------------------------------------------------
TH_3810|M.thermoresistible__bu --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_1264|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_0868|M.smegmatis_MC2_155 MHERLRERAGGVRKTLSDFAEGAGLKPSDTDDTRSPLRKPKFPAALAPES
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 --------------------------------------------------
MAV_4827|M.avium_104 --------------------------------------------------
Mb1849c|M.bovis_AF2122/97 --MSFVVTIPEALAAVATDLAGIGSTIGTANAAAAVPTTTVLAAAADEVS
Rv1818c|M.tuberculosis_H37Rv --MSFVVTIPEALAAVATDLAGIGSTIGTANAAAAVPTTTVLAAAADEVS
MUL_3704|M.ulcerans_Agy99 --MSYVLVTPEMVATAAADAAAIGSTVSAANAAAAIPTTAIATAAADDVS
MMAR_3758|M.marinum_M --MSYVLVTPEMVATAAADAAAIGSTVSAANAAAAIPTTAIATAAADDVS
TH_3810|M.thermoresistible__bu --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_1264|M.vanbaalenii_PYR-1 -------------------MMFLAPPGGPGPISAAIQLTSTGSEATEP--
MSMEG_0868|M.smegmatis_MC2_155 PLPDLKPRWERPTTAPDSETPSITQPQGRDTAADPAEQQATSTNTTDQPT
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 --MSIIDFILNLFRDPVEAASYVADPEAALANAGLSAVSAAQVGAVMPVV
MAV_4827|M.avium_104 --MNIVLGVSMAPSSIQMVVLEGEYADGATVEEDAIDVTGADDAATASAP
Mb1849c|M.bovis_AF2122/97 ------------------------------------AAMAALFSGHAQAY
Rv1818c|M.tuberculosis_H37Rv ------------------------------------AAMAALFSGHAQAY
MUL_3704|M.ulcerans_Agy99 ------------------------------------AAIAALFNAHAEQY
MMAR_3758|M.marinum_M ------------------------------------AAIAALFNAHAEQY
TH_3810|M.thermoresistible__bu --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK --------------------------------------MVTFGGGATPTP
Mvan_1264|M.vanbaalenii_PYR-1 ------------------------------------WYVVSFGGSGAPTP
MSMEG_0868|M.smegmatis_MC2_155 SDSLGAQPTAQVARQVQAPATDPAPAAPSLRPISGLLSVVTLGTTLIPNA
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 AES--------------------------------VASNYGYQSQWVNTG
MAV_4827|M.avium_104 DR--------------------------------VISAILGTREGAADAG
Mb1849c|M.bovis_AF2122/97 ----------------------------------------QALSAQAALF
Rv1818c|M.tuberculosis_H37Rv ----------------------------------------QALSAQAALF
MUL_3704|M.ulcerans_Agy99 ----------------------------------------QALSVRVAEF
MMAR_3758|M.marinum_M ----------------------------------------QALSVRVAEL
TH_3810|M.thermoresistible__bu --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK ----------------------------------------TSLGAAAVDL
Mvan_1264|M.vanbaalenii_PYR-1 ----------------------------------------NNLAASLVDL
MSMEG_0868|M.smegmatis_MC2_155 PTEPADMPGVWAVMAWARRQPMYSDPAMRTTVNPQAQLPVPTVASAVLDP
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 -------------------------------------NPIHDLSGNLQNY
MAV_4827|M.avium_104 -------------------------------------LQLSSIGVTWTDQ
Mb1849c|M.bovis_AF2122/97 HEQ---------------------FVRALTAGAGSYAAAEAASAAPLEGV
Rv1818c|M.tuberculosis_H37Rv HEQ---------------------FVRALTAGAGSYAAAEAASAAPLEGV
MUL_3704|M.ulcerans_Agy99 HES---------------------FTRALTAGSTAYATAEAANAGPLQPL
MMAR_3758|M.marinum_M HES---------------------FTRALTAGSTAYATAEAANAGPLQPL
TH_3810|M.thermoresistible__bu --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK S------------------------GTSCG----------LICNGQDGTG
Mvan_1264|M.vanbaalenii_PYR-1 S------------------------GTSCG----------LICNGQDGTG
MSMEG_0868|M.smegmatis_MC2_155 TQIVNWLIYQPLHAAGQQFWVVSPIGSTLGGVINTISGQYLIGNGINGTA
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 YAAQ----------PDGPSILSPSLLSPRDNDFLSHNDTDFASHNPIASG
MAV_4827|M.avium_104 LEAAALR---------------DALAARRIDNVMLVSAFLAAAALAQNVG
Mb1849c|M.bovis_AF2122/97 LDVINAPALALLGRPLIGNGANGAPGTGANGGDGGILIG--NGGAGGSGA
Rv1818c|M.tuberculosis_H37Rv LDVINAPALALLGRPLIGNGANGAPGTGANGGDGGILIG--NGGAGGSGA
MUL_3704|M.ulcerans_Agy99 LDLINAPTQALLARPLIGDGTNGAPGTGQAGGNGGLLVG--NGGAGG---
MMAR_3758|M.marinum_M LDLINAPTQALLARPLIGDGSNGAPGTGQAGGNGGLLIG--NGGAGGSGA
TH_3810|M.thermoresistible__bu -----------------------VDGDGGSGGRTGLFSKLSRGGDGGDGG
Mflv_5091|M.gilvum_PYR-GCK QN-----GGILFGNGGSGWNSDVVGMDGGNGGNGGLFGG--NGGNGGNGL
Mvan_1264|M.vanbaalenii_PYR-1 QN-----GGILFGNGGSGWNSEIAGVSGGNGGNAGLFGG--NGGNGGNGL
MSMEG_0868|M.smegmatis_MC2_155 DNPNGGTGGLLFGDGGHGYDGSAAGLAGGNGGNAGLFG---NGGNGGVGW
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 NQVMSPSGNVDSFNRGPLLDLSFGDLQFGNRDTTAIGDGAVAVGGSNSGP
MAV_4827|M.avium_104 GAMGYERTAVLLVEPDTATLAVVETSDGSIPDVYKQQIRAESYGDAAGQL
Mb1849c|M.bovis_AF2122/97 AGMPGGNGGAAG--------------------------------LFGNGG
Rv1818c|M.tuberculosis_H37Rv AGMPGGNGGAAG--------------------------------LFGNGG
MUL_3704|M.ulcerans_Agy99 -------------------------------------------LLFGQGG
MMAR_3758|M.marinum_M PGQRGGAGGAGGLLLGNGGAGGAGGVGALGQASGTGGNGGAGGLLFGKGG
TH_3810|M.thermoresistible__bu LGGNGGHGGGTGII-----------------------------SLLSLAG
Mflv_5091|M.gilvum_PYR-GCK GGGNGGNGGNAGAF-----------------------------ALFGNGG
Mvan_1264|M.vanbaalenii_PYR-1 GSGDGGNGGDAGLF-----------------------------SLFGRGG
MSMEG_0868|M.smegmatis_MC2_155 AGLDGGNGGSGG-------------------------------LLMGIGG
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 IASGQGSTAVNGDVRD---------------------------SNIINAD
MAV_4827|M.avium_104 SAMVAGLEKLESLPGG---------------------------LLLVGSG
Mb1849c|M.bovis_AF2122/97 AGGAGGNVASG-------------------------------------TA
Rv1818c|M.tuberculosis_H37Rv AGGAGGNVASG-------------------------------------TA
MUL_3704|M.ulcerans_Agy99 AG------------------------------------------------
MMAR_3758|M.marinum_M AGGAGGVGGLGQAGGTGGNGGAGGLLFGNGGAGGVGGAGGVGGVDSAGGT
TH_3810|M.thermoresistible__bu NGGNGGNGYR--------------------------------TTDNNALD
Mflv_5091|M.gilvum_PYR-GCK NGGNGGVGVVGATGAVG------------------APGVAGATGATGVTS
Mvan_1264|M.vanbaalenii_PYR-1 NGGNGGVGIAGATGAVG------------------APGVAGATGATGVTS
MSMEG_0868|M.smegmatis_MC2_155 AGGAGGVGADGTSAHVDGG----------------TGGTGGTGGGTGGTG
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 HGSNVGVDQSQTRVGGDYTN---------------VSGHGSADIDKSVTV
MAV_4827|M.avium_104 VDVAPLKQVLQTTTFLDVS--------------------VAEEPETALAR
Mb1849c|M.bovis_AF2122/97 GFGGAGGAGGLLYGAGGAGGAGGRAGGGVGGIG---------------GA
Rv1818c|M.tuberculosis_H37Rv GFGGAGGAGGLLYGAGGAGGAGGRAGGGVGGIG---------------GA
MUL_3704|M.ulcerans_Agy99 -------GANGLFEAAGSGGSGGAGGDGAPGD-----------------S
MMAR_3758|M.marinum_M GGTGGTGGANGLFGAAGSGGSGGAGGDGAPGD-----------------T
TH_3810|M.thermoresistible__bu GGHGGNGGNVGFFSLFNLGGAGGWGGSGVDG----------------VDV
Mflv_5091|M.gilvum_PYR-GCK GVVGGNGEDAVGYGATGAAGAAGAAGAAGAAG--------------AVGS
Mvan_1264|M.vanbaalenii_PYR-1 NVTGGNGADAVGYGATGAAGAAGAAGAAGKAG--------------AVGS
MSMEG_0868|M.smegmatis_MC2_155 GIGGTGGGLFGLLGHSGSTGAAGAAGNGGDGGNGGFGYVLIAGPNVTVGS
MLBr_01183|M.leprae_Br4923 ---------MPLFLNAEPQALTAAAN------------------------
MAB_4284c|M.abscessus_ATCC_199 VDDHSQRNTTNINDSFNTDRSTNIGSGNTTNTEIG--------SHNQANI
MAV_4827|M.avium_104 GAALAAANAPLFASSTAALAYAQDPGTGAVDQYSLP------DYLYVPVD
.
Mb1849c|M.bovis_AF2122/97 GGAGGNGGLLFGAG-GAGSVGGLAADAGDGG-------------------
Rv1818c|M.tuberculosis_H37Rv GGAGGNGGLLFGAG-GAGGVGGLAADAGDGG-------------------
MUL_3704|M.ulcerans_Agy99 GTAGGTGGTGSARG--AGGTGGVGGANQFFG-------------------
MMAR_3758|M.marinum_M AGAGGTGGTGSAGG--AGGTGGAGGANQFFG-------------------
TH_3810|M.thermoresistible__bu VGGNPDGGTPGAHG--ESHTPGVYTDR-----------------------
Mflv_5091|M.gilvum_PYR-GCK AGAAGEAGETGTWG--NAGLPGKAGDAGGAG----------------AVG
Mvan_1264|M.vanbaalenii_PYR-1 AGTAGSAGAPGVWG--NAGLPGAAGAAGGAG----------------AIG
MSMEG_0868|M.smegmatis_MC2_155 ETRGGTGGAGGTGGQSTAAGPGKGGGGGGGGGGAILIGANGGTVDGHAIG
MLBr_01183|M.leprae_Br4923 ----------TLEG--LSAATVASN-------------------------
MAB_4284c|M.abscessus_ATCC_199 GTSTSAGGSAAVGG--NAGLAGNAGLAGNAG-------------------
MAV_4827|M.avium_104 PEPGDDELAYSAVGEEDAESPTVVIEKLFLP-------------------
* .
Mb1849c|M.bovis_AF2122/97 ---------------------------------------AGGDG--GLFF
Rv1818c|M.tuberculosis_H37Rv ---------------------------------------AGGDG--GLFF
MUL_3704|M.ulcerans_Agy99 ---------------------------------------HAGDGGHGGTG
MMAR_3758|M.marinum_M ---------------------------------------HAGDGGHGGTG
TH_3810|M.thermoresistible__bu ---------------------------------------QGEDGEDGTGT
Mflv_5091|M.gilvum_PYR-GCK AAGAAG------TVGTAGATGGTG---------------TGANGGAGGVG
Mvan_1264|M.vanbaalenii_PYR-1 TAGVAG------AAGTAGATGGTG---------------VGGNGGAGQAG
MSMEG_0868|M.smegmatis_MC2_155 GNGGNGGNGSTTAAGGNGGTGGTGRVIAEGTGSTAEGTATGGDGGHSTGT
MLBr_01183|M.leprae_Br4923 ------------------------------------------AAAAQLTT
MAB_4284c|M.abscessus_ATCC_199 --------------------------------------LAGNAGLAGNAG
MAV_4827|M.avium_104 ---------------------------------------EDSEPRRRPVL
Mb1849c|M.bovis_AF2122/97 GVG-GAGGAG----------------------------------------
Rv1818c|M.tuberculosis_H37Rv GVG-GAGGAG----------------------------------------
MUL_3704|M.ulcerans_Agy99 GAG-GTGGAG----------------------------------------
MMAR_3758|M.marinum_M GTG-GTGGAG----------------------------------------
TH_3810|M.thermoresistible__bu GIG-GRGGNG----------------------------------------
Mflv_5091|M.gilvum_PYR-GCK GVG-GTGAAG--------------AAGGAGGLGETGTTGGAGGVGGQ--G
Mvan_1264|M.vanbaalenii_PYR-1 GIG-GTGAAG--------------AAGQAGTAGETGVTGGVGGIGGQ--G
MSMEG_0868|M.smegmatis_MC2_155 GIG-GNGGIGSVYAYGNNGAVSGTATGGRGGDGIDGGTGGAGGMGEIYSG
MLBr_01183|M.leprae_Br4923 EIA-PPAADD----------------------------------------
MAB_4284c|M.abscessus_ATCC_199 LAG-NAGLAG----------------------------------------
MAV_4827|M.avium_104 LVGSGLAVVG----------------------------------------
. . .
Mb1849c|M.bovis_AF2122/97 ----------GTGTNVTGGAGGAGGNG-----------------------
Rv1818c|M.tuberculosis_H37Rv ----------GTGTNVTGGAGGAGGNG-----------------------
MUL_3704|M.ulcerans_Agy99 --GSGVGSGLAGGTGGDGGVGGAAGRG-----------------------
MMAR_3758|M.marinum_M --GSGVGSGLAGGAGGDGGAGGAAGRG-----------------------
TH_3810|M.thermoresistible__bu --------------GSSSGTHPMAEDG-----------------------
Mflv_5091|M.gilvum_PYR-GCK TAGGTGGVGGIGGAGSTGAVGGVGGKG----IQGGQG-------------
Mvan_1264|M.vanbaalenii_PYR-1 TEGGTGGVGGVGGVGATGGAGGVGGKG----IQGGQG-------------
MSMEG_0868|M.smegmatis_MC2_155 ADGEATGISAGGDGGSATGADSLGGRGGTSWVQAGYGPTTGGKASGTAKA
MLBr_01183|M.leprae_Br4923 --------------VSILLAHFFSGHG-----------------------
MAB_4284c|M.abscessus_ATCC_199 ------NAGLAGNAGLAGNAGLAGNAG-----------------------
MAV_4827|M.avium_104 -------------ISAVLALEIALAIG-----------------------
*
Mb1849c|M.bovis_AF2122/97 --GLLFGAGGVGGVGGDGVAFLG----------------------TAPGG
Rv1818c|M.tuberculosis_H37Rv --GLLFGAGGVGGVGGDGVAFLG----------------------TAPGG
MUL_3704|M.ulcerans_Agy99 ---GAADAGGPLVTPGHAG----------------------NTGTGGTGG
MMAR_3758|M.marinum_M ---GAAGAGGPLVTPGHAG----------------------NTGTGGTGG
TH_3810|M.thermoresistible__bu -EHVKALDGRPGLDGG----------------------------NGSHGG
Mflv_5091|M.gilvum_PYR-GCK LQGGKGGDGGAGGKGGDADSMGS------------------AGATGGKGG
Mvan_1264|M.vanbaalenii_PYR-1 LQGGQGGDGGTGGTGGDATSMGE------------------AGATGGKGG
MSMEG_0868|M.smegmatis_MC2_155 GHGGKASDGGKGGNGGDALVMAAGATGVATGNTAIGGNGGAASANGAVGG
MLBr_01183|M.leprae_Br4923 ----RQYQAHAS-----------------------------------QGA
MAB_4284c|M.abscessus_ATCC_199 LAGNAGLAGNAGLAGNAGLAGNAG-----------------LAGNAGLAG
MAV_4827|M.avium_104 ----IRTTGTVALQPTPNQHLIVP-----------------TEQAPAPPP
.
Mb1849c|M.bovis_AF2122/97 PGGAGGAGGLFG--------------------------------------
Rv1818c|M.tuberculosis_H37Rv PGGAGGAGGLFG--------------------------------------
MUL_3704|M.ulcerans_Agy99 TGGTGGNGDLHTD-------------------------------------
MMAR_3758|M.marinum_M TGGTGGNGDLHTN-------------------------------------
TH_3810|M.thermoresistible__bu NGGHGGRGGFLG--------------------------------------
Mflv_5091|M.gilvum_PYR-GCK NGGNGGRGGLFG---------------KGGNAGNGAD-------------
Mvan_1264|M.vanbaalenii_PYR-1 NGGNGGRGSLFG---------------RGGNAGNGGN-------------
MSMEG_0868|M.smegmatis_MC2_155 NGGFTNIAAIHGSITDSSATSGHGGAAQGGNGGNGGNGWVQAYDPNGPAG
MLBr_01183|M.leprae_Br4923 TNHQDLIQSLLT--------------------------------------
MAB_4284c|M.abscessus_ATCC_199 NAGLAGNAGLAGN-------------------------------------
MAV_4827|M.avium_104 VQASAPQPKISVP-------------------------------------
:
Mb1849c|M.bovis_AF2122/97 --------VGGAGGAGGIGLVGN--GGAGGSGG-----------------
Rv1818c|M.tuberculosis_H37Rv --------VGGAGGAGGIGLVGN--GGAGGSGG-----------------
MUL_3704|M.ulcerans_Agy99 ---------GGNGGTGG-SGGAGIAGVGGGNG------------------
MMAR_3758|M.marinum_M ---------GGNGGTGG-SGGAGIAGVGGGNGG-----------------
TH_3810|M.thermoresistible__bu --------IGGSGGWGGHGGNGGDTDADGGNGG-----------------
Mflv_5091|M.gilvum_PYR-GCK ---------GGTGGAGGAGGTGG-TGGAGGTGG-----------------
Mvan_1264|M.vanbaalenii_PYR-1 ---------GGTGGNGGNGGTGG-TGGNGGTGG-----------------
MSMEG_0868|M.smegmatis_MC2_155 TTIDKGKAAGGNGGDGGFNGTGGATGGRGGDGAGASVWKANGQHSTGQTD
MLBr_01183|M.leprae_Br4923 ----------SSSAYAG-------TETANHDSL-----------------
MAB_4284c|M.abscessus_ATCC_199 ---------AGLAGNAGLAGNAGLAGNAGLAGN-----------------
MAV_4827|M.avium_104 ---------EPVAAPKPLSPPVAAPLPAAPPPAAP---------------
..
Mb1849c|M.bovis_AF2122/97 -------------------------------------SALLWGDGGAGGA
Rv1818c|M.tuberculosis_H37Rv -------------------------------------SALLWGDGGAGGA
MUL_3704|M.ulcerans_Agy99 --------------------------------------------------
MMAR_3758|M.marinum_M TGGDGGKGGTGANGAPLGASGGTGGDGGKGGGGGNATDGGHGGNGGTGGT
TH_3810|M.thermoresistible__bu -------------------------------------DGGNGGSAGRGGT
Mflv_5091|M.gilvum_PYR-GCK TGGTGGIGGAGSTGGTGGTGGTGGTGGTGGTG-GTGGTGGTGGTGGKGGT
Mvan_1264|M.vanbaalenii_PYR-1 TGGTGGIGGAGSTGGTGGTGGTGGTGGTGGTG-GTGGTGGTGGTGGKGGT
MSMEG_0868|M.smegmatis_MC2_155 TGGNGGRGGDGGTFVNAGANGNGGAGGAGGVSEGEGGTGGHGGDGGRGGD
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 --------------------------------AAVAGNAAVAGNAAVAGN
MAV_4827|M.avium_104 ---------------------------------PLPEAPPIPAAPPVVPV
Mb1849c|M.bovis_AF2122/97 GGVGSTT-----------------------------------------GG
Rv1818c|M.tuberculosis_H37Rv GGVGSTT-----------------------------------------GG
MUL_3704|M.ulcerans_Agy99 --------------------------------------------------
MMAR_3758|M.marinum_M AGDGGNGQSGDLNANGGGGGRGGTGGAGGIGGTTTGGGDAGAGGGGGAGG
TH_3810|M.thermoresistible__bu GGLRGVFGIN--------------------------------------GG
Mflv_5091|M.gilvum_PYR-GCK GGTGGAGGTG---------GDGGTGGTGGTGGTG---------GTGGTGG
Mvan_1264|M.vanbaalenii_PYR-1 GGTGGDGGTG---------GTGGTGGTGGTGGTG---------GTGGTGG
MSMEG_0868|M.smegmatis_MC2_155 GALGGNGGTGGV-----GLGNGGKGGNGGNGGNGGTYVDPSHTGAGGNGG
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 AAVGGVLNTG---------------------------------VSGAIGG
MAV_4827|M.avium_104 PVVVPPVPVP-------------------------------------VPV
Mb1849c|M.bovis_AF2122/97 AGGAG---------------------------------------------
Rv1818c|M.tuberculosis_H37Rv AGGAG---------------------------------------------
MUL_3704|M.ulcerans_Agy99 --------------------------------------------------
MMAR_3758|M.marinum_M TGGSGGEGGAGGFGGDGGAGGTGGKAGAGGDGGNATDGGNAGAGGDGGTG
TH_3810|M.thermoresistible__bu NGRAG-----------------------------LGGRGXXXX-------
Mflv_5091|M.gilvum_PYR-GCK TGGAG-----------DGTGGTGGTGG----TGGQGGQGGQGG-------
Mvan_1264|M.vanbaalenii_PYR-1 TGGAG-----------DGLGGTGGTGG----TGGFGGQGGQGG-------
MSMEG_0868|M.smegmatis_MC2_155 NGGAGRIRVNNGTATGTATGGNGGNGGNGDADGHRGGKGGDGGEALIRAT
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 SSHVG-----------------------GAINESLGGSGSVGG-------
MAV_4827|M.avium_104 RIPVP---------------------------------------------
Mb1849c|M.bovis_AF2122/97 --------------------------------------------------
Rv1818c|M.tuberculosis_H37Rv --------------------------------------------------
MUL_3704|M.ulcerans_Agy99 --------------------------------------------------
MMAR_3758|M.marinum_M GAGGTGGGIVTGINGGAGGAGGDGGDSGNGGNATGGGNGGNGGTAGTGGA
TH_3810|M.thermoresistible__bu ----------GGGVG-----------------------------------
Mflv_5091|M.gilvum_PYR-GCK ----------TGGTGGQGG-LGGGGGTG----------------------
Mvan_1264|M.vanbaalenii_PYR-1 ----------TGGTGGQGG-LGGVGGTG----------------------
MSMEG_0868|M.smegmatis_MC2_155 VIGSNASGTATGGDGGNGGTLGATNGTGGAATIVAYNVVQANPQASGTAT
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 --------------------------------------------------
MAV_4827|M.avium_104 --------------------------------------------------
Mb1849c|M.bovis_AF2122/97 --------------------------------------GNAGLLVGAGGA
Rv1818c|M.tuberculosis_H37Rv --------------------------------------GNAGLLVGAGGA
MUL_3704|M.ulcerans_Agy99 --------------------------------------------------
MMAR_3758|M.marinum_M GGLGGGGFRVGHGGGGGNGGNGGVG--------GTATAGGDAGSGGTGGV
TH_3810|M.thermoresistible__bu ----------------------------------AAVRSGNGVFSGGGGT
Mflv_5091|M.gilvum_PYR-GCK -GQGGTGGTGGQGGTGGTGGTGGTG--------GTGGAGGDGGLGGLGGF
Mvan_1264|M.vanbaalenii_PYR-1 -GTGGTGGTGGQGGTGGTGGTGGTG--------GTGGAGGDGGLGGLGGF
MSMEG_0868|M.smegmatis_MC2_155 DGHGGSGINGGHGGNGGQGTIEANGPSAVASGIGAGGNGGDGIDGGLGGN
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 -----------------------------------STAVGGGAHTGVGGG
MAV_4827|M.avium_104 -----------------------------------DPVSPPQLLAPPRLS
Mb1849c|M.bovis_AF2122/97 GGAGALGG------------------------------------------
Rv1818c|M.tuberculosis_H37Rv GGAGALGG------------------------------------------
MUL_3704|M.ulcerans_Agy99 --------------------------------------------------
MMAR_3758|M.marinum_M GGDGSVGGDASDAVAGGDGGTGGRGGSGGAGGIATGGGSAGHGGVGGGGG
TH_3810|M.thermoresistible__bu PSAGFGVPTTIQFPAGSCTSRAVSREGIMPSSRAAS--------------
Mflv_5091|M.gilvum_PYR-GCK GGSGGTGGQGGLGGPGGSTGGAGGAGG--QAGTAGKGGLFG-----GSGS
Mvan_1264|M.vanbaalenii_PYR-1 GGVGGTGGQGGQGGPGGSTGGAGGAGG--QAGVAGKGGLFG-----GSGS
MSMEG_0868|M.smegmatis_MC2_155 GGDGVVNTTANAANPGSATGTATGGDGGKATGTASQGGNGGPSWV-QSGY
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 VSTGVGVGSHVGGGISESLGGSGSVGGSTAVGGGAHTGVGG-----GVST
MAV_4827|M.avium_104 VPQPVQPPVRVPQPPSPPQVGGTVPQSPPQHQTPPGEGTPPKPDGPGNYG
Mb1849c|M.bovis_AF2122/97 ----GATGVGGAGGNGGTAGLLFGAGGAG-------------GAGGFGFG
Rv1818c|M.tuberculosis_H37Rv ----GATGVGGAGGNGGTAGLLFGAG----------------GAGGFGFG
MUL_3704|M.ulcerans_Agy99 --GHGTDGSAGVAGHGGGAGGAGGDAGDG------GKGGDALDGGTAGTG
MMAR_3758|M.marinum_M NGGHGTDGTAGVAGHGGGAGGAGGDAGDG------GKGGDALDGGTAGAG
TH_3810|M.thermoresistible__bu -ARAGAACASSTSRSRRSFCCSRA--------------------------
Mflv_5091|M.gilvum_PYR-GCK AGKAGATGAAGASGGKGAQGATGAQGATG------AQGATG-ATGAAGKA
Mvan_1264|M.vanbaalenii_PYR-1 AGTAGVTGASGASGGKGAQGATGAQGATG------AQGATG-ATGASGAQ
MSMEG_0868|M.smegmatis_MC2_155 GSTLGGNATGTATAGKGGEASNGGVAGNGGNALVMAAGTTGVATGNTATG
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 GVGVGSHVGGGISESLGGSGSVGGSTAVG-------GGAHTGVGGGVNTG
MAV_4827|M.avium_104 GGHVPTPGAGGSGGSGGGHVPTPGAGGSG--------GSGGGHVPTPGTG
Mb1849c|M.bovis_AF2122/97 GAGGAGGLGGKAGLIG-------------------------DGGDGGAGG
Rv1818c|M.tuberculosis_H37Rv GAGGAGGLGGKAGLIG-------------------------DGGDGGAGG
MUL_3704|M.ulcerans_Agy99 GAGGNAGNGGGAGSGG---------------------KGTFDGGAGGAGG
MMAR_3758|M.marinum_M GAGGKAGNGGGAGSGG---------------------KGTFDGGAGGAGG
TH_3810|M.thermoresistible__bu --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK GATGAAGAAGAAGSAG-----------TTGAQGSAGTNGA-NGANGSQGA
Mvan_1264|M.vanbaalenii_PYR-1 GSAGSAGSAGVAGSAG-----------TTGAQGSAGTNGA-NGANGSQGA
MSMEG_0868|M.smegmatis_MC2_155 GDGGAATTAGATGGAGGFSNIAAIHGAITDSTAISGHGGAGNGGNGGKGA
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 VGVGSHVGGGISESLG---------------------GSGSVGGSTAVGG
MAV_4827|M.avium_104 GPGGTGGSGGGHVPTPG------------------------AGTPGGSGG
Mb1849c|M.bovis_AF2122/97 NGTG--------------------AKGGDGGAGGGAILVGNG--------
Rv1818c|M.tuberculosis_H37Rv NGTG--------------------AKGGDGGAGGGAILVGNG--------
MUL_3704|M.ulcerans_Agy99 DGGK-------------------AGNGGAGGIDSNGQVADGG--------
MMAR_3758|M.marinum_M DGGK-------------------AGNGGAGGIDSNGQVADGGD-------
TH_3810|M.thermoresistible__bu --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK AGKAGATGTTGATG--------AAGEDGDAGSGGSG-INGGAGGAGG---
Mvan_1264|M.vanbaalenii_PYR-1 AGKAGATGTTGATG--------AAGDAGDPGSEAVD-INGGAGGAGG---
MSMEG_0868|M.smegmatis_MC2_155 DGWVQAYDPAGPVGSKIANSSAVAGNGGDGGVNGTGGASGGDGGNGGNTS
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 GAHTSAIN---------------DALGGSGSVGGSTAVGGGAHTSAIN--
MAV_4827|M.avium_104 GHLPFP-----------------GAGSTPGGSGGGHLPTPGAGTPG----
Mb1849c|M.bovis_AF2122/97 ----------------GNGGNAGSGTP-----------------------
Rv1818c|M.tuberculosis_H37Rv ----------------GNGGNAGSGTP-----------------------
MUL_3704|M.ulcerans_Agy99 --------------NGGDGGNGGDGSP--------VGAGGTGGIG--TAG
MMAR_3758|M.marinum_M ---------GGDGGNGGDGGNGGDGSP--------VGAGGTGGIG--TAG
TH_3810|M.thermoresistible__bu --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK --------AGGEGGEGGDGGKGGAGAE--------GGAGGGGGAGGSGAG
Mvan_1264|M.vanbaalenii_PYR-1 --------AGGEGGEGGAGGAGGDGSE--------GGAGGSGGAGGSGTG
MSMEG_0868|M.smegmatis_MC2_155 VWKSGGQTADGEHNTGGNGGNGGDGSEPGPGGNGAGGAGGNGGTGGTTAG
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 -------------ESMNSSINASHSSS--------MNESFGSSMGSHGAA
MAV_4827|M.avium_104 ---------------GGLGGFGGGHAP-------------APGGGLGGGG
Mb1849c|M.bovis_AF2122/97 -------NGSAGTGGAGGLLGKNGMNGLP--
Rv1818c|M.tuberculosis_H37Rv -------NGSAGTGGAGGLLGKNGMNGLP--
MUL_3704|M.ulcerans_Agy99 GAG----GGGGAVSGRPGQNGSEGQPG----
MMAR_3758|M.marinum_M GAG----GGGGAVSGRPGQNGSEGQPG----
TH_3810|M.thermoresistible__bu -------------------------------
Mflv_5091|M.gilvum_PYR-GCK GAG--GAGGSGGSGGSGGSGGSGGAAGDSDD
Mvan_1264|M.vanbaalenii_PYR-1 GAG--GAGGSGGSGGSGGAGGSGGAAGDSD-
MSMEG_0868|M.smegmatis_MC2_155 GSGNGGNGGNGGNGGADGTPGTAGTTGANNP
MLBr_01183|M.leprae_Br4923 -------------------------------
MAB_4284c|M.abscessus_ATCC_199 GTGFEAQGHAQGHASETAHTTLPGAEHH---
MAV_4827|M.avium_104 GHAPAPGGGLGGFGGGHSGGGLGGLGGGHK-