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VDPEHRTRNPYRSTAANLMHNGVLDAMHGLLLVKKWSSITMADVASAAGISRGTLYNEFQSRRGLARHYA LRLTDSIVTGMQTAISENHGNGYSAMQTVFSDFFHRVANDPLAQVLRTEDAPNDILRLITVESQFLVDHA TEQLSQTFQHSWVNANEYDAAVMGQAMVRAALSYLALPPSDADEAAKGMAHLLAPYIDSVNRAR*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. ulcerans Agy99 | MUL_2746 | - | - | 100% (205) | TetR family transcriptional regulator |
| M. ulcerans Agy99 | MUL_2593 | - | 3e-39 | 42.93% (191) | TetR family transcriptional regulator |
| M. ulcerans Agy99 | MUL_4837 | - | 3e-05 | 19.51% (164) | transcriptional regulatory protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3277c | - | 4e-40 | 43.46% (191) | TetR family transcriptional regulator |
| M. gilvum PYR-GCK | Mflv_4718 | - | 6e-41 | 41.88% (191) | TetR family transcriptional regulator |
| M. tuberculosis H37Rv | Rv3249c | - | 4e-40 | 43.46% (191) | TetR family transcriptional regulator |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_3596c | - | 9e-41 | 41.15% (192) | TetR family transcriptional regulator |
| M. marinum M | MMAR_3519 | - | 1e-115 | 99.51% (205) | TetR family transcriptional regulator |
| M. avium 104 | MAV_4212 | - | 8e-42 | 43.46% (191) | putative transcriptional regulatory protein |
| M. smegmatis MC2 155 | MSMEG_1842 | - | 2e-41 | 41.84% (196) | transcriptional regulator, TetR family protein |
| M. thermoresistible (build 8) | TH_0467 | - | 4e-42 | 44.50% (191) | POSSIBLE TRANSCRIPTIONAL REGULATORY PROTEIN (PROBABLY |
| M. vanbaalenii PYR-1 | Mvan_1745 | - | 4e-41 | 41.88% (191) | TetR family transcriptional regulator |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_4718|M.gilvum_PYR-GCK -MTAQPIATSARVATRHADQRRADTRARGASLGPVRATVIVAPVGG-GND
Mvan_1745|M.vanbaalenii_PYR-1 -MRATHRAEPC----RHARSRNTASQGTAVTASAGPGTITVARVGL-SND
TH_0467|M.thermoresistible__bu ---------------------------------------VVSRR-----D
MSMEG_1842|M.smegmatis_MC2_155 MIHAVTHAVAG---------AQFGAPARVVRGPLTAESDIVARVSRPRAK
Mb3277c|M.bovis_AF2122/97 ---------------------------------MSTPSATVAPV------
Rv3249c|M.tuberculosis_H37Rv ---------------------------------MSTPSATVAPV------
MAV_4212|M.avium_104 -------------------------------------------M------
MAB_3596c|M.abscessus_ATCC_199 -MTDVLP----------GRDALTSASVPARLPGVTRPDALRAGGSS----
MUL_2746|M.ulcerans_Agy99 ---------------------------------------MVDPEHR----
MMAR_3519|M.marinum_M --------------------------------MRTNLSYMVDPEHR----
Mflv_4718|M.gilvum_PYR-GCK KRISYAEASRVLLRDSILDGMREMLLARDWSQITLSDVAKAAGISRQTIY
Mvan_1745|M.vanbaalenii_PYR-1 KRVSYAEASRVLLRDSILDGMREMLLTRDWSAITLSDVAKAAGISRQTIY
TH_0467|M.thermoresistible__bu KRVPYAEASRVLLRDSILDGMRELLQTRDWSQITLADVAKAAGISRQTIY
MSMEG_1842|M.smegmatis_MC2_155 QRMPYAEASRVLLRDSILDGMRDLLLTRDWSAITLSHVAQAAGVSRQTIY
Mb3277c|M.bovis_AF2122/97 KRIPYAEASRALLRDSVLDAMRDLLLTRDWSAITLSDVARAAGISRQTIY
Rv3249c|M.tuberculosis_H37Rv KRIPYAEASRALLRDSVLDAMRDLLLTRDWSAITLSDVARAAGISRQTIY
MAV_4212|M.avium_104 KRMPYAEASRALLRDSVLDAMRDLLVTRDWSAITLSDVARAAGISRQTIY
MAB_3596c|M.abscessus_ATCC_199 HRVPYAEAARALLRESVLDALGDLLRQRDWSAVTMSDVSRRAGVSRQTLY
MUL_2746|M.ulcerans_Agy99 TRNPYRSTAANLMHNGVLDAMHGLLLVKKWSSITMADVASAAGISRGTLY
MMAR_3519|M.marinum_M TRNPYRSTAANLMHNGVLDAMHGLLLVKKWSSITMADVASAAGISRGTLY
* .* .:: *:::.:**.: :* :.** :*::.*: **:** *:*
Mflv_4718|M.gilvum_PYR-GCK NEFGSRQGLAQGYAMRLADRLVDQIHAAIDNNVGDMYAAFLQGFRDFFVE
Mvan_1745|M.vanbaalenii_PYR-1 NEFGSRQGLAQGYAMRLADRLVDQIHGAINGNAGDVYAAFLQGFRDFFVE
TH_0467|M.thermoresistible__bu NEFGSRQGLAQGYALRLADRLVDEVDEAIANNVGDIHAAFLAGFRKFFAE
MSMEG_1842|M.smegmatis_MC2_155 NEFGSRQGLAEGYAMRLADRLVDAVDDAINNNVGDVYAAFLEGFRAFFAE
Mb3277c|M.bovis_AF2122/97 NEFGSRQGLAQGYALRLADRLVDNVHASLDANVGNFYEAFLQGFRSFFAE
Rv3249c|M.tuberculosis_H37Rv NEFGSRQGLAQGYALRLADRLVDNVHASLDANVGNFYEAFLQGFRSFFAE
MAV_4212|M.avium_104 NEFGSRQGLAQGYALRLADRLVDTIHEALDAHVGNIYESFLDAFRRFFAD
MAB_3596c|M.abscessus_ATCC_199 NEFGSRQGLAQGYALRLAHRLVDAVGDAIYAHVGDIHGALHSGFADFFAE
MUL_2746|M.ulcerans_Agy99 NEFQSRRGLARHYALRLTDSIVTGMQTAISENHGNGYSAMQTVFSDFFHR
MMAR_3519|M.marinum_M NEFQSRRGLARHYALRLTDSIVTGMQTAISENHGNGYSAMQTVFSDFFHR
*** **:***. **:**:. :* : :: : *: : :: * **
Mflv_4718|M.gilvum_PYR-GCK SAADPLVISLLTGSSKPDLLQLITTDSAPIINHCSSRLTESLMGSWVRCS
Mvan_1745|M.vanbaalenii_PYR-1 SAADPLVISLLTGTSKPDLLQLITTDSAPIINHCSSRLTESFMSSWVRVS
TH_0467|M.thermoresistible__bu SAADPLVISLLTGSAKPDLLQLITTDSAPIITRASQRLTESFQSSWVRAS
MSMEG_1842|M.smegmatis_MC2_155 SAADPLVISLLTGAAKPDLLQIITIGSGPIITRCSERLTATFQSSWIKAS
Mb3277c|M.bovis_AF2122/97 SAADPLVISLLTGVAKPDLLQLITTDSAPIITRASARLAPAFTDTWVATT
Rv3249c|M.tuberculosis_H37Rv SAADPLVISLLTGVAKPDLLQLITTDSAPIITRASARLAPAFTDTWVATT
MAV_4212|M.avium_104 AAADPLVTSLRTGVAKPDLLQLITTDSAVIITRASARLASALTHTWVSTT
MAB_3596c|M.abscessus_ATCC_199 SAADPMVISLLTGEAKPELMRIVTVDSALIVVPASARLTESFMNSWVAAS
MUL_2746|M.ulcerans_Agy99 VANDPLAQVLRTEDAPNDILRLITVESQFLVDHATEQLSQTFQHSWVNAN
MMAR_3519|M.marinum_M VANDPLAQVLRTEDAPNDILRLITVESQFLVDHATEQLSQTFQHSWVNAN
* **:. * * : ::::::* * :: .: :*: :: :*: .
Mflv_4718|M.gilvum_PYR-GCK EEDAGVLSRAIVRLAMSYISMPPEADHDVARDLARLMTPFAERYGVVADP
Mvan_1745|M.vanbaalenii_PYR-1 QEDAGVLARAIVRLAMSYISMPPEADHDVARDLARLMTPFAERYGVIDP-
TH_0467|M.thermoresistible__bu EEDAGVLARAIVRLAMSYVSMPPEADHDVAHDLARLMTPFAERYGVIEEV
MSMEG_1842|M.smegmatis_MC2_155 DDDAGVLARAIVRLAMSYVSMPPEADHDVAGDLARLMSPFAERYGVIDTP
Mb3277c|M.bovis_AF2122/97 DNDANVLSRAIVRLCLSYVSMPPEADHDVAADLARLITPFAERHGVINVP
Rv3249c|M.tuberculosis_H37Rv DNDANVLSRAIVRLCLSYVSMPPEADHDVAADLARLITPFAERHGVINVP
MAV_4212|M.avium_104 DEDAGVLARAIVRLALSYVSMPPEADHDVAADLARLMTPFAERHGVVNVG
MAB_3596c|M.abscessus_ATCC_199 QEDASILARSIVRLAISYVSMPPESDHDVALDMARLLSPFVETNALADKA
MUL_2746|M.ulcerans_Agy99 EYDAAVMGQAMVRAALSYLALPPSDADEAAKGMAHLLAPYIDSVNRAR--
MMAR_3519|M.marinum_M EYDAAVMGQAVVRAALSYLALPPSDADEAAKGMAHLLAPYIDSVNRAR--
: ** ::.:::** .:**:::**. .:.* .:*:*::*: :
Mflv_4718|M.gilvum_PYR-GCK VEGGNSQVTRRP
Mvan_1745|M.vanbaalenii_PYR-1 ------------
TH_0467|M.thermoresistible__bu ------------
MSMEG_1842|M.smegmatis_MC2_155 ------------
Mb3277c|M.bovis_AF2122/97 ------------
Rv3249c|M.tuberculosis_H37Rv ------------
MAV_4212|M.avium_104 ------------
MAB_3596c|M.abscessus_ATCC_199 ------------
MUL_2746|M.ulcerans_Agy99 ------------
MMAR_3519|M.marinum_M ------------