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MSTIDAVNRAAPDSSAHHALPDAGETVPKLALPTLGIFLAALGSFVLTTVGYIDGWVPSWVTIPVNAAVT FVMFTVVHYASHYSVSSVRWVNGLFGRLAFLFVGPVVAFPAFGYIHIQHHRHSNDDVEDPDTFASHGSPW LLPLRWSLVEYYYLKYYIPRARSRPVVEFAETLFMFALSITGLTIAIVTGNFWTLAVVFLIPQRIGLTVL AWWFDWLPHHGLEDTQRTNRYRATRNRVGAEWLFTPVLLSQNYHLVHHLHPSVPFYRYVRTWKRNEEAYL ERNAAISTVFGQQLNPDEYREWKELNGRLAKLLPVRMPVRSSSPHAVLHRIPVASVDPITTDSTLVTFAV PEDLQDAFRFEPGQHVTVRTDLGGQGVRRNYSICAPATRAQLRIAVKHIPGGAFSTFVANDRKAGDVLEL MTPTGQFGTPLNPLERKHYVGLVAGSGTTPVLSILATTLEIEAESRFTLIYGNRTKESTMFRAELDRLES RYADRLEILHVMSNEPLHTPELRGRIDTEKLNRWLTSNLSPETVDEWFICGPMEMTTTVRDSLIEHGVDT EHIHLELFFGYNTAPATDHGYEGATVTFTLSGRQDTFDLTPGDSILEVALQRRSDAPYACMGGACGTCRA KLIEGNVEMDHNFALGQAELDAGYILTCQSHPTTPFVAVDYDS
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. ulcerans Agy99 | MUL_4117 | fdxB | - | 100% (673) | electron transfer protein FdxB |
| M. ulcerans Agy99 | MUL_4142 | hmp | 2e-37 | 31.74% (356) | flavodoxin reductase Hmp |
| M. ulcerans Agy99 | MUL_2566 | - | 2e-20 | 26.58% (316) | oxidoreductase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3584 | fdxB | 0.0 | 84.99% (673) | electron transfer protein FdxB |
| M. gilvum PYR-GCK | Mflv_2468 | - | 2e-44 | 31.94% (335) | ferredoxin |
| M. tuberculosis H37Rv | Rv3554 | fdxB | 0.0 | 84.99% (673) | electron transfer protein FdxB |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_0910 | - | 5e-70 | 41.26% (349) | putative phenylacetic acid degradation protein |
| M. marinum M | MMAR_5043 | fdxB | 0.0 | 98.81% (673) | electron transfer protein FdxB |
| M. avium 104 | MAV_0590 | - | 1e-39 | 32.40% (358) | oxidoreductase, electron transfer component |
| M. smegmatis MC2 155 | MSMEG_0295 | - | 5e-41 | 33.33% (336) | oxidoreductase, FAD-binding |
| M. thermoresistible (build 8) | TH_0316 | - | 1e-38 | 31.59% (364) | POSSIBLE HEMOGLOBINE-RELATED PROTEIN HMP |
| M. vanbaalenii PYR-1 | Mvan_4186 | - | 4e-42 | 30.97% (339) | ferredoxin |
CLUSTAL 2.0.9 multiple sequence alignment
MUL_4117|M.ulcerans_Agy99 -------------MSTIDAVNRAAPDSSAHHALPDAGETVPKLALPTLGI
MMAR_5043|M.marinum_M -------------MSTIDAVNRAAPDSSAHHALPDPGETVPKLALPTLGI
Mb3584|M.bovis_AF2122/97 MTDACQAEYAIAAMSTVEMD-QAAPESAAHHPLPDPGESVPRLALPTIGI
Rv3554|M.tuberculosis_H37Rv MTDACQAEYAIAAMSTVEMD-QAAPESAAHHPLPDPGESVPRLALPTIGI
MAB_0910|M.abscessus_ATCC_1997 --------------------------------------------------
Mflv_2468|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_4186|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_0295|M.smegmatis_MC2_155 --------------------------------------------------
MAV_0590|M.avium_104 --------------------------------------------------
TH_0316|M.thermoresistible__bu --------------------------------------------------
MUL_4117|M.ulcerans_Agy99 FLAALGSFVLTTVGYIDGWVPSWVTIPVNAAVTFVMFTVVHYASHYSVSS
MMAR_5043|M.marinum_M FLAALGSFVLTTVGYIDGWVPFWVTIPVNAAVTFVMFTVVHDASHYSVSS
Mb3584|M.bovis_AF2122/97 FLATLTAFVGSTTAYISGWIPFWVTIPVNAAVTFVMFTVVHDASHYAISS
Rv3554|M.tuberculosis_H37Rv FLATLTAFVGSTTAYISGWIPFWVTIPVNAAVTFVMFTVVHDASHYAISS
MAB_0910|M.abscessus_ATCC_1997 --------------------------------------------------
Mflv_2468|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_4186|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_0295|M.smegmatis_MC2_155 --------------------------------------------------
MAV_0590|M.avium_104 --------------------------------------------------
TH_0316|M.thermoresistible__bu --------------------------------------------------
MUL_4117|M.ulcerans_Agy99 VRWVNGLFGRLAFLFVGPVVAFPAFGYIHIQHHRHSNDDVEDPDTFASHG
MMAR_5043|M.marinum_M VRWVNGLFGRLAFLFVGPVVAFPAFGYIHIQHHRHSNDDVEDPDTFASHG
Mb3584|M.bovis_AF2122/97 IRWVNGLFGRLAWLFVGPVVAFPAFGYIHIQHHRHSNDDEQDPDTFASHG
Rv3554|M.tuberculosis_H37Rv IRWVNGLFGRLAWLFVGPVVAFPAFGYIHIQHHRHSNDDEQDPDTFASHG
MAB_0910|M.abscessus_ATCC_1997 --------------------------------------------------
Mflv_2468|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_4186|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_0295|M.smegmatis_MC2_155 --------------------------------------------------
MAV_0590|M.avium_104 --------------------------------------------------
TH_0316|M.thermoresistible__bu --------------------------------------------------
MUL_4117|M.ulcerans_Agy99 SPWLLPLRWSLVEYYYLKYYIPRARSRPVVEFAETLFMFALSITGLTIAI
MMAR_5043|M.marinum_M SPWLLPLRWSLVEYYYLKYYIPRARSRPVVEFAETLFMFALSITGLTIAI
Mb3584|M.bovis_AF2122/97 SLWVLPLRWSMVEYFYIKYYLPRGRSRPVIEVAETLVMMTLFLTGLIVAI
Rv3554|M.tuberculosis_H37Rv SLWVLPLRWSMVEYFYIKYYLPRGRSRPVIEVAETLVMMTLFLTGLIVAI
MAB_0910|M.abscessus_ATCC_1997 ------------------------------------------MTTELSAP
Mflv_2468|M.gilvum_PYR-GCK ------------------------------------------MVEELS--
Mvan_4186|M.vanbaalenii_PYR-1 ------------------------------------------MAEELTDP
MSMEG_0295|M.smegmatis_MC2_155 -----------------------------------------MAAMETSTA
MAV_0590|M.avium_104 -----------------------------------------MTEADSAQA
TH_0316|M.thermoresistible__bu -----------------------------------------MVDAEISR-
MUL_4117|M.ulcerans_Agy99 VTGNFWTLAVVFLIPQRIGLTVLAWWFDWLPHHGLEDTQRTNRYRATRNR
MMAR_5043|M.marinum_M VTGNFWTLAVVFLIPQRIGLTVLAWWFDWLPHHGLEDTQRTNRYRATRNR
Mb3584|M.bovis_AF2122/97 VTGNFWTLAIVFLIPQRIGLTVLAWWFDWLPHHGLEDTQRSNRYRATRNR
Rv3554|M.tuberculosis_H37Rv VTGNFWTLAIVFLIPQRIGLTVLAWWFDWLPHHGLEDTQRSNRYRATRNR
MAB_0910|M.abscessus_ATCC_1997 TTG-----------------------------------------RGMRNR
Mflv_2468|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_4186|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_0295|M.smegmatis_MC2_155 PLDEPAGL------------------------------------------
MAV_0590|M.avium_104 LDEPL---------------------------------------------
TH_0316|M.thermoresistible__bu --------------------------------------------------
MUL_4117|M.ulcerans_Agy99 VGAEWLFTPVLLSQNYHLVHHLHPSVPFYRYVRTWKRNEEAYLERNAAIS
MMAR_5043|M.marinum_M VGAEWLFTPVLLSQNYHLVHHLHPSVPFYRYVRTWKRNEEAYLERNAAIS
Mb3584|M.bovis_AF2122/97 VGAEWLFTPVLLSQNYHLVHHLHPSVPFYRYLRTWRRNEEAYLERNAAIS
Rv3554|M.tuberculosis_H37Rv VGAEWLFTPVLLSQNYHLVHHLHPSVPFYRYLRTWRRNEEAYLERNAAIS
MAB_0910|M.abscessus_ATCC_1997 P---------------------------FRTVR-----------------
Mflv_2468|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_4186|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_0295|M.smegmatis_MC2_155 --------------------------------------------------
MAV_0590|M.avium_104 --------------------------------------------------
TH_0316|M.thermoresistible__bu --------------------------------------------------
MUL_4117|M.ulcerans_Agy99 TVFGQQLNPDEYREWKELNGRLAKLLPVRMPVRSSSPHAVLHRIPVASVD
MMAR_5043|M.marinum_M TVFGQQLNPDEYRQWKELNGRLAKLLPVRMPARSSSPHAVLHRIPVASVD
Mb3584|M.bovis_AF2122/97 TVFGQQLNPDEYRQWKELNGRLARLLPVRMPARSSSPHAVLHRIPVASVD
Rv3554|M.tuberculosis_H37Rv TVFGQQLNPDEYRQWKELNGRLARLLPVRMPARSSSPHAVLHRIPVASVD
MAB_0910|M.abscessus_ATCC_1997 ---------------------------------------------VAEVQ
Mflv_2468|M.gilvum_PYR-GCK -------------------------------------VDGFAPLRIKRVV
Mvan_4186|M.vanbaalenii_PYR-1 -------------------------------------AEGFAPLRIRRVV
MSMEG_0295|M.smegmatis_MC2_155 -----------------------------------TDADGFTPLRVKDVI
MAV_0590|M.avium_104 -------------------------------------GDHVLELQIAEVI
TH_0316|M.thermoresistible__bu -------------------------------------GPRAVRLTVAAVI
: *
MUL_4117|M.ulcerans_Agy99 PITTDSTLVTFAVPEDLQ------DAFRFEPGQHVTVRTDLGGQ-GVRRN
MMAR_5043|M.marinum_M PITTDSTLVTFAVPEDLQ------DAFRFEPGQHVTVRTDLGGQ-GVRRN
Mb3584|M.bovis_AF2122/97 PITADATLVTFAVPEALR------DAFRFEPGQHVTVRTDLGGQ-GIRRN
Rv3554|M.tuberculosis_H37Rv PITADATLVTFAVPEALR------DAFRFEPGQHVTVRTDLGGQ-GIRRN
MAB_0910|M.abscessus_ATCC_1997 QLCADAAAITFAVPDQYI------DEFGFAPGQSITVRRNVDGV-EQRRT
Mflv_2468|M.gilvum_PYR-GCK RETSDAVSLVLDVPEDCS------HRFRYKAGQFLTVRVSVDGR-DLRRC
Mvan_4186|M.vanbaalenii_PYR-1 RETADAVSLVLDVPECCS------HRFQYKAGQFLTLRVSVGGR-DLRRC
MSMEG_0295|M.smegmatis_MC2_155 RETTDAVSLILDVPELIE------DRFRYTAGQFVTVKTTIRGE-EHRRC
MAV_0590|M.avium_104 AETDDARSLVFAVPDDDGDPDIPPERLRYAPGQFLTLRVPSERTGSVARC
TH_0316|M.thermoresistible__bu DESPDARSLVFEVPEEHR------TRFVYRPGQFLTLRIPGDRTGSVARC
*: : : **: : : .** :*:: *
MUL_4117|M.ulcerans_Agy99 YSI-CAPATRAQLRIAVKHIPGGAFSTFVANDRKAGDVLELMTPTGQFGT
MMAR_5043|M.marinum_M YSI-CAPATRAQLRIAVKHIPGGAFSTFVANDLKAGDVLELMTPTGQFGT
Mb3584|M.bovis_AF2122/97 YSI-CAPATRAQLRIAVKHIPGGAFSTFVANELKAGDVLELMTPTGRFGT
Rv3554|M.tuberculosis_H37Rv YSI-CAPATRAQLRIAVKHIPGGAFSTFVANELKAGDVLELMTPTGRFGT
MAB_0910|M.abscessus_ATCC_1997 YSI-CSPLG-ARPRIGVREVPGGACSGWLVHQLSAGDEIEVQPPSGNF--
Mflv_2468|M.gilvum_PYR-GCK YSMSSAP-VEEELRITVKRDPGGLVSNWINDTAAEGDELHASPPEGRFTL
Mvan_4186|M.vanbaalenii_PYR-1 YSMSSAP-VEDELRITVKRDPGGVVSNWINDTAAAGDELHAAPPEGRFTL
MSMEG_0295|M.smegmatis_MC2_155 YSMSSSPHVGPDLRITVKRDRDGVVSNWINDTAAAGDRLLTAPPDGRFVL
MAV_0590|M.avium_104 YSLCSSPFTDDALTVTVKRTADGYASNWLCDNARPGMRIHVLAPSGNFVP
TH_0316|M.thermoresistible__bu YSLASSPHTDDAMKVTVKRTDGGYGSNWLCDNAEPGTTIEALPPAGTFTP
**: .:* : *:. .* * :: . * : .* * *
MUL_4117|M.ulcerans_Agy99 PLNPLERKHYVGLVAGSGTTPVLSILATTLEIEAESRFTLIYGNRTKEST
MMAR_5043|M.marinum_M PLNPLERKHYVGLVAGSGITPVLSILATTLEIEAESRFTLIYGNRTKEST
Mb3584|M.bovis_AF2122/97 PLDPLHRKHYVGLVAGSGITPVLSILATTLEIETESRFTLIYGNRTKEST
Rv3554|M.tuberculosis_H37Rv PLDPLHRKHYVGLVAGSGITPVLSILATTLEIETESRFTLIYGNRTKEST
MAB_0910|M.abscessus_ATCC_1997 VADATTPAHHVLIAAGSGITPLLSIAASVLAQP-DSRVTLLYGNRRANTV
Mflv_2468|M.gilvum_PYR-GCK AEGVSSPRPLIAFAGGSGITPIMSLVRAALADT-ARPVRLFYANRARGSV
Mvan_4186|M.vanbaalenii_PYR-1 TESDSSPRELVAFAGGSGITPIMSLVRAALAGS-DRTVKLFYANRGRDSV
MSMEG_0295|M.smegmatis_MC2_155 T---TADRDVVTFAGGSGVTPVFSLVNTTLATT-GRRVRMFYANRDADSV
MAV_0590|M.avium_104 K---TLGDDFLLMAAGSGITPIMSIAKSALSEG-SGRVTLLYANRDERSV
TH_0316|M.thermoresistible__bu A---SLDGAFLLWAAGSGITPVMSILKSVLEAG-TGRVILCYANRDERSV
: ..*** **::*: :.* . : *.** :.
MUL_4117|M.ulcerans_Agy99 MFRAELDRLESRYADRLEILHVMSNEPLHTPELRGRIDTEKLNRWLTSNL
MMAR_5043|M.marinum_M MFRAELDRLESRYADRLEILHVMSNEPLHTPELRGRIDTEKLNRWLTSNL
Mb3584|M.bovis_AF2122/97 MFRAELDRLESRYADRLEILHVLSSEPLHTPELRGRIDRDKLTRWLTSTL
Rv3554|M.tuberculosis_H37Rv MFRAELDRLESRYADRLEILHVLSSEPLHTPELRGRIDRDKLTRWLTSTL
MAB_0910|M.abscessus_ATCC_1997 MFADELADLKDTYHSRLQLVHVLSREPRTVELFSGRLDHQRIRVLLQQLV
Mflv_2468|M.gilvum_PYR-GCK IFSEPLARLTEQHADRLTVAHHFDED-------AGVVTATAVASFAES--
Mvan_4186|M.vanbaalenii_PYR-1 IFSEPLARLAEQHADRLTVEHHYDED-------AGVVTASAVESFAAR--
MSMEG_0295|M.smegmatis_MC2_155 IFRDALTRLTDSHSDRLHVHHHLDTR-------DGVVSARHITEFLGAST
MAV_0590|M.avium_104 IFADALRELSAKYPDRLTVLHWLESL-------QGLPSVTALAQLAAP--
TH_0316|M.thermoresistible__bu IFAGELRELAARHAGRFTVLHWLESV-------QGLPTTAQMYRFARL--
:* * * : .*: : * . * :
MUL_4117|M.ulcerans_Agy99 SPETVDEWFICGPMEMTTTVRDSLIEHGVDTEHIHLELFFGYNTAPATDH
MMAR_5043|M.marinum_M SPETVDEWFICGPMEMTTTVRDSLIEHGVDTEHIHLELFFGYNTAPATDH
Mb3584|M.bovis_AF2122/97 RPAGVDEWFICGPLAMATAVRETLIEHGVDSERIHLELFYGFDTPPATRP
Rv3554|M.tuberculosis_H37Rv RPAGVDEWFICGPLAMATAVRETLIEHGVDSERIHLELFYGFDTPPATRP
MAB_0910|M.abscessus_ATCC_1997 PIAAVDHVWLCGPFGMVTDAQAALRELGVEDSRIHQELFFVEDAAPPQAE
Mflv_2468|M.gilvum_PYR-GCK --AGDADYYICGPAPFMDTVEASLLDSGVPKQRLNLERFTIAEVPPG---
Mvan_4186|M.vanbaalenii_PYR-1 --VGDADFYVCGPTPFMDTVETALLGAGVPKQRLHLERFTVAAAPDT---
MSMEG_0295|M.smegmatis_MC2_155 VSTAEADFYICGPAPFMDTVERVLLDAGVPAQRVHLERFTVTPADP----
MAV_0590|M.avium_104 --YTDRPVYICGPGAFMDSAREALETLKVPAAQIHIEVFKSLDSDPFAAV
TH_0316|M.thermoresistible__bu --FTDHESFVCGPEPFMAVVTAALTEAGVPRNQIHTEVFRSLTGDPFTDE
::*** : . * * ::: * *
MUL_4117|M.ulcerans_Agy99 G-----YEGAT------VTFTLSGRQDTFDLTPGDSILEVALQRRSDAPY
MMAR_5043|M.marinum_M G-----YEGAT------VTFTLSGRQDTFDLTPGDSILEGALQRRSDAPY
Mb3584|M.bovis_AF2122/97 S-----YAGAT------VTFTLSGQRAIFDLVPGDSILEGALGLRSDAPY
Rv3554|M.tuberculosis_H37Rv S-----YAGAT------VTFTLSGQRAIFDLVPGDSILEGALGLRSDAPY
MAB_0910|M.abscessus_ATCC_1997 H-----RDGVASGPVSEVTIVLDGATSTMALPRNVSVLDAAQRSRDDLPF
Mflv_2468|M.gilvum_PYR-GCK ------VTDNTDDACEEIVIELDRQKVTAAYRQGETLLQTARQKGLKAPA
Mvan_4186|M.vanbaalenii_PYR-1 ------VTDGDAQACEEVVIELQRQKVTAAYRQGDTLLQTARLQGLKAPS
MSMEG_0295|M.smegmatis_MC2_155 ------AVEAESAATEEVTIVLGRTTVTQPYRAGTTLLQTARLAGLKAPS
MAV_0590|M.avium_104 KIED---TAEGDEPPATAVVELDGETHTVSWPRNAKLLDVLLAKGLDAPF
TH_0316|M.thermoresistible__bu PVGEPDGTIADERPPAEAVVVLDGETHVCEWPRTATLLDTMLARGLDAPY
.. * .:*: . *
MUL_4117|M.ulcerans_Agy99 ACMGGACGTCRAKLIEGNVEMDHNFALGQAELDAGYILTCQSHPTTPFVA
MMAR_5043|M.marinum_M ACMGGACGTCRAKLIEGNVEMDHNFALGQAELDAGYILTCQSHPTTPFVA
Mb3584|M.bovis_AF2122/97 ACMGGACGTCRAKLIEGNVEMDHNFALRKAELDAGYILTCQSHPTTPFVA
Rv3554|M.tuberculosis_H37Rv ACMGGACGTCRAKLIEGNVEMDHNFALRKAELDAGYILTCQSHPTTPFVA
MAB_0910|M.abscessus_ATCC_1997 ACKGGVCGTCRAKVTGGAVDMRRNYALEPDEIDAGFVLTCQSYPTTDSLT
Mflv_2468|M.gilvum_PYR-GCK SCETGSCGTCMARIVEGSARMRINDALDEDEVEEGWVLTCQSLPTSRKVH
Mvan_4186|M.vanbaalenii_PYR-1 SCETGSCGTCMARIVEGSARMLNNDALEPDEVEEGWVVTCQALPTSSKVH
MSMEG_0295|M.smegmatis_MC2_155 SCEVGTCGTCIGQVVEGSARLLNNDALDDDEIAEGWVVTCQALPTSHTVK
MAV_0590|M.avium_104 SCREGHCGACACTLRKGQVSMEVNDVLEQQDLDEGLILACQSHPESDSVE
TH_0316|M.thermoresistible__bu SCREGNCGSCAATVLEGEVDRGHSDILDPQDVADGLILACQTRPNSDSVR
:* * **:* : * . . * :: * :::**: * : :
MUL_4117|M.ulcerans_Agy99 VDYDS
MMAR_5043|M.marinum_M VDYDS
Mb3584|M.bovis_AF2122/97 VDYDA
Rv3554|M.tuberculosis_H37Rv VDYDA
MAB_0910|M.abscessus_ATCC_1997 VDFDA
Mflv_2468|M.gilvum_PYR-GCK VVYE-
Mvan_4186|M.vanbaalenii_PYR-1 MIYE-
MSMEG_0295|M.smegmatis_MC2_155 VVYE-
MAV_0590|M.avium_104 VTYDD
TH_0316|M.thermoresistible__bu IEF--
: :