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M. ulcerans Agy99 MUL_4142 (hmp)

annotation: flavodoxin reductase Hmp
coordinates: 4614705 - 4615781
length: 358

LTDAIPDEPLGSHVLELQIAEVVAETDDARSLVFAVPDGSDDPRIPPERLRYAPGQFLTLRVPSERTGSV
ARCYSLCSSPFTDDALTVTVKRTADGYASNWLCDNAHQGMRIHVLAPSGNFVPKTLDDDFLLLAAGSGIT
PIMSICKSALAEGGGQVTLLYANRDERSVIFADALRELSAKYPDRLTVVHWLESLQGLPSATALAQLAAP
FTGRTAFICGPGPFMEAARVALQTLDVPAGQVHIEVFKSLESDPFAAVTVEDSAAEPPATAVVELDGQTH
TVSWPRSAKLLDVLLAAGLDAPFSCREGHCGACAATLRSGKVNMEVNDVLEQQDLDDGLILACQSHPESD
SVEVTYDE
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. ulcerans Agy99MUL_4142hmp-100% (358)flavodoxin reductase Hmp
M. ulcerans Agy99MUL_4117fdxB1e-3731.74% (356) electron transfer protein FdxB
M. ulcerans Agy99MUL_2566-1e-2126.91% (353) oxidoreductase

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb3602hmp0.088.27% (358) hemoglobine-like protein
M. gilvum PYR-GCKMflv_1462-1e-15473.41% (361) ferredoxin
M. tuberculosis H37RvRv3571hmp0.088.27% (358) hemoglobine-like protein
M. leprae Br4923-----
M. abscessus ATCC 19977MAB_0583c-1e-14168.54% (356) putative oxidoreductase
M. marinum MMMAR_5066hmp0.099.44% (358) flavodoxin reductase Hmp
M. avium 104MAV_0590-1e-18087.29% (354) oxidoreductase, electron transfer component
M. smegmatis MC2 155MSMEG_6039-1e-15375.56% (356) oxidoreductase, electron transfer component
M. thermoresistible (build 8)TH_1743-1e-15776.82% (358) POSSIBLE HEMOGLOBINE-RELATED PROTEIN HMP
M. vanbaalenii PYR-1Mvan_5309-1e-15674.65% (359) ferredoxin

CLUSTAL 2.0.9 multiple sequence alignment


MUL_4142|M.ulcerans_Agy99           MTDAIP----DEPLGSHVLELQIAEVVAETDDARSLVFAVPDGSDDPRIP
MMAR_5066|M.marinum_M               MTDAIP----DEPLGSHVLELQIAEVVAETDDARSLVFAVPDGSDDPRIP
Mb3602|M.bovis_AF2122/97            MTEAIG----DEPLGDHVLELQIAEVVDETDEARSLVFAVPDGSDDPEIP
Rv3571|M.tuberculosis_H37Rv         MTEAIG----DEPLGDHVLELQIAEVVDETDEARSLVFAVPDGSDDPEIP
MAV_0590|M.avium_104                MTEADSAQALDEPLGDHVLELQIAEVIAETDDARSLVFAVPDDDGDPDIP
MSMEG_6039|M.smegmatis_MC2_155      ----MT----DEPLGSHVLELQVAEVVEETSDARSLVFTVPEG---AEIA
TH_1743|M.thermoresistible__bu      ----VT----DEPLGSHVLELQVAEVVEETADARSLVFTVPDG---VDIP
Mflv_1462|M.gilvum_PYR-GCK          MTDVAA----DEPLGAHVLELEIADVIDETSDARSLVFRSPAD---APVA
Mvan_5309|M.vanbaalenii_PYR-1       MTDVAA----DEPLGTHVLELEIADVIDETADARSLVFKSPAD---APVP
MAB_0583c|M.abscessus_ATCC_199      ----MT----DVPLGKHVLEVRIAEVIEETADSRSLVFEIPDG------A
                                              * *** ****:.:*:*: ** ::*****  * .      .

MUL_4142|M.ulcerans_Agy99           PERLRYAPGQFLTLRVPSERTGSVARCYSLCSSPFTDDALTVTVKRTADG
MMAR_5066|M.marinum_M               PERLRYAPGQFLTLRVPSERTGSVARCYSLCSSPFTDDALTVTVKRTADG
Mb3602|M.bovis_AF2122/97            PRRLRYAPGQFLTLRVPSERTGSVARCYSLCSSPYTDDALAVTVKRTADG
Rv3571|M.tuberculosis_H37Rv         PRRLRYAPGQFLTLRVPSERTGSVARCYSLCSSPYTDDALAVTVKRTADG
MAV_0590|M.avium_104                PERLRYAPGQFLTLRVPSERTGSVARCYSLCSSPFTDDALTVTVKRTADG
MSMEG_6039|M.smegmatis_MC2_155      ADRLRYSPGQFLTLRVPSDRTGSVARCYSLSSSPTTDDRLTVTVKRTADG
TH_1743|M.thermoresistible__bu      PERLRYAPGQFLTLRVPSDRTGSVARCYSLCSSPFTGDPMTVTVKRTEDG
Mflv_1462|M.gilvum_PYR-GCK          PEKLRYSPGQFLTLRVPSEKTGSVARCYSLCSSPFTGDPLTVTIKRTADG
Mvan_5309|M.vanbaalenii_PYR-1       PEKLRYAPGQFLTLRVPSDRTGSVARCYSLCSSPFTGDPLTVTVKRTADG
MAB_0583c|M.abscessus_ATCC_199      ADKFAYAPGQYLTLRIPSDRTGSVARCYSLSSSPHLDDRLAVTVKRTADG
                                    . :: *:***:****:**::**********.***  .* ::**:*** **

MUL_4142|M.ulcerans_Agy99           YASNWLCDNAHQGMRIHVLAPSGNFVPKTLDDDFLLLAAGSGITPIMSIC
MMAR_5066|M.marinum_M               YASNWLCDNAHQGMRIHVLAPSGNFVPKTLDDDFLLLAAGSGITPIMSIC
Mb3602|M.bovis_AF2122/97            YASNWLCDHAQVGMRIHVLAPSGNFVPTTLDADFLLLAAGSGITPIMSIC
Rv3571|M.tuberculosis_H37Rv         YASNWLCDHAQVGMRIHVLAPSGNFVPTTLDADFLLLAAGSGITPIMSIC
MAV_0590|M.avium_104                YASNWLCDNARPGMRIHVLAPSGNFVPKTLGDDFLLMAAGSGITPIMSIA
MSMEG_6039|M.smegmatis_MC2_155      YASNWLCDNAHAGMRIHVLAPSGTFVPKDLDTDFLLLAAGSGITPMMAIC
TH_1743|M.thermoresistible__bu      YASNWLCDNAHPGMRIHVLAPSGTFVPKSLDADFLLLAAGSGITPMMAIC
Mflv_1462|M.gilvum_PYR-GCK          YASNWLCDNAHAGMKMHVLAPSGTFVPKNLDTDFLLLAAGSGITPMLAIL
Mvan_5309|M.vanbaalenii_PYR-1       YASNWLCDNAHAGMRIHVLAPSGTFVPRSLDTDFLLLAAGSGITPMLAIL
MAB_0583c|M.abscessus_ATCC_199      YGSNWICDNAHAGMHMHVLAPSGVFVPKQLDNDFLLLAGGSGVTPMMAIC
                                    *.***:**:*: **::******* ***  *. ****:*.***:**:::* 

MUL_4142|M.ulcerans_Agy99           KSALAEGGGQVTLLYANRDERSVIFADALRELSAKYPDRLTVVHWLESLQ
MMAR_5066|M.marinum_M               KSTLAEGSGQVTLLYANRDERSVIFADALRELSAKYPDRLTVVHWLESLQ
Mb3602|M.bovis_AF2122/97            KSALAEGGGQVTLLYANRDDRSVIFGDALRELAAKYPDRLTVLHWLESLQ
Rv3571|M.tuberculosis_H37Rv         KSALAEGGGQVTLLYANRDDRSVIFGDALRELAAKYPDRLTVLHWLESLQ
MAV_0590|M.avium_104                KSALSEGSGRVTLLYANRDERSVIFADALRELSAKYPDRLTVLHWLESLQ
MSMEG_6039|M.smegmatis_MC2_155      KSALAEGTGNVVLIYANRDENSVIFAGALRELAAKYPDRLTVVHWLETVQ
TH_1743|M.thermoresistible__bu      KSALAEGSGQVVLVYANRDENSVIFSAALRDLAAKYPDRLTVVHWLESVQ
Mflv_1462|M.gilvum_PYR-GCK          KSALSEGSGHVTLVYANRDEKSVIFAETLRDLANKYPDRLTTIHWLESVQ
Mvan_5309|M.vanbaalenii_PYR-1       KSALSEGTGKVTLVYANRDEKSVIFAETLRDLAAKYPDRLTAIHWLESVQ
MAB_0583c|M.abscessus_ATCC_199      KSALSQGSGKVVLIYANRDEQSVIFGAALRELAAKYPDRLTVIHWLESVQ
                                    **:*::* *.*.*:*****:.****. :**:*: *******.:****::*

MUL_4142|M.ulcerans_Agy99           GLPSATALAQLAAPFTGRTAFICGPGPFMEAARVALQTLDVPAGQVHIEV
MMAR_5066|M.marinum_M               GLPSATALAQLAAPFTGRTAFICGPGPFMEAARVALQTLDVPAGQVHIEV
Mb3602|M.bovis_AF2122/97            GLPSASALAKLVAPYTDRPVFICGPGPFMQAARDALAALKVPAQQVHIEV
Rv3571|M.tuberculosis_H37Rv         GLPSASALAKLVAPYTDRPVFICGPGPFMQAARDALAALKVPAQQVHIEV
MAV_0590|M.avium_104                GLPSVTALAQLAAPYTDRPVYICGPGAFMDSAREALETLKVPAAQIHIEV
MSMEG_6039|M.smegmatis_MC2_155      GLPTAAGLGALAKPFAGREAFICGPGPFMTAAEDALRAAGTPDDHIHIEV
TH_1743|M.thermoresistible__bu      GLPTVAALTGLVRPYAAHDAFICGPAPFMAAAEEALTNVGAPADRIHIEV
Mflv_1462|M.gilvum_PYR-GCK          GLPSVSALTALFAPFTSREAFICGPGPFMAAAEEALTASGAAADKIHIEV
Mvan_5309|M.vanbaalenii_PYR-1       GLPSVSALTELFEPYGAREAFVCGPGPFMAASEEALKAAGLPAERIHIEV
MAB_0583c|M.abscessus_ATCC_199      GLPSQQQLATLTAPFAEHEAFICGPGPFMDASEAALKGNGMPHDRVHIEV
                                    ***:   *  *  *:  : .::***..** ::. **     .  ::****

MUL_4142|M.ulcerans_Agy99           FKSLESDPFAAVTVE---DSA--AEPPATAVVELDGQTHTVSWPRSAKLL
MMAR_5066|M.marinum_M               FKSLESDPFAAVTVE---DSA--AEPPATAVVELDGQTHTVSWPRSAKLL
Mb3602|M.bovis_AF2122/97            FKSLESDPFAAVKVD---DSG--DEAPATAVVELDGQTHTVSWPRTAKLL
Rv3571|M.tuberculosis_H37Rv         FKSLESDPFAAVKVD---DSG--DEAPATAVVELDGQTHTVSWPRTAKLL
MAV_0590|M.avium_104                FKSLDSDPFAAVKIE---DTAEGDEPPATAVVELDGETHTVSWPRNAKLL
MSMEG_6039|M.smegmatis_MC2_155      FKSLESDPFAAVVIPE-DDGDD--QGPATAVVTLDGTTHEIRWPRSAKLL
TH_1743|M.thermoresistible__bu      FKSLESDPFATVVVDY-DEAGEGGEGPATAIVTLDGQTHEVTWPRSAKLL
Mflv_1462|M.gilvum_PYR-GCK          FKSLDSDPFAAVTIDDADDEGD--SGPATVVVTLDGETHEVSWPRKAKLL
Mvan_5309|M.vanbaalenii_PYR-1       FKSLESDPFAAVKIE--EDDSD--EGPATAIVTLDGQTHEVSWPRRAKLL
MAB_0583c|M.abscessus_ATCC_199      FRSLESDPFAEVVLAEPSDDD---EPPATATVELDGETHEVSWPRSTVLL
                                    *:**:***** * :    :     . ***. * *** ** : *** : **

MUL_4142|M.ulcerans_Agy99           DVLLAAGLDAPFSCREGHCGACAATLRSGKVNMEVNDVLEQQDLDDGLIL
MMAR_5066|M.marinum_M               DVLLAAGLDAPFSCREGHCGACAATLRSGKVNMEVNDVLEQQDLDDGLIL
Mb3602|M.bovis_AF2122/97            DVLLAAGLDAPFSCREGHCGACACTLRAGKVNMGVNDVLEQQDLDEGLIL
Rv3571|M.tuberculosis_H37Rv         DVLLAAGLDAPFSCREGHCGACACTLRAGKVNMGVNDVLEQQDLDEGLIL
MAV_0590|M.avium_104                DVLLAKGLDAPFSCREGHCGACACTLRKGQVSMEVNDVLEQQDLDEGLIL
MSMEG_6039|M.smegmatis_MC2_155      DVLLDKGLDAPFSCREGHCGACAVLKKSGEVHMEINDVLEPSDLEEGLIL
TH_1743|M.thermoresistible__bu      DVLLDKGLDAPFSCREGHCGACAVVKKSGEVEMEVNDVLEQSDLDEGLIL
Mflv_1462|M.gilvum_PYR-GCK          DVLLNKGLDAPFSCREGHCGACAVLKKSGDIEMEVNDVLEQQDLDEGLIL
Mvan_5309|M.vanbaalenii_PYR-1       DVLLDKGLDAPFSCREGHCGACAVLKKSGDTEMEINDVLEQQDLDEGLIL
MAB_0583c|M.abscessus_ATCC_199      DVLLAKGLDAPFSCREGHCMTCACVLKDGKVRMLVNDALSQNDIDDGYIL
                                    ****  ************* :**   : *.  * :**.*. .*:::* **

MUL_4142|M.ulcerans_Agy99           ACQSHPESDSVEVTYDE
MMAR_5066|M.marinum_M               ACQSHPESDSVEVTYDE
Mb3602|M.bovis_AF2122/97            ACQSRPESDSVEVTYDE
Rv3571|M.tuberculosis_H37Rv         ACQSRPESDSVEVTYDE
MAV_0590|M.avium_104                ACQSHPESDSVEVTYDD
MSMEG_6039|M.smegmatis_MC2_155      GCQATPVSDSVEVTYDE
TH_1743|M.thermoresistible__bu      GCQARPLSDSVEVTYDE
Mflv_1462|M.gilvum_PYR-GCK          ACQAHPTSDSVEVTFDE
Mvan_5309|M.vanbaalenii_PYR-1       ACQAHPTSDSVEVTYDE
MAB_0583c|M.abscessus_ATCC_199      ACQAVPETDDVNVTFDE
                                    .**: * :*.*:**:*: