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MNEFVSVVADQGLATLVVFRPPTNAMTRQVYREIVAAADELGRRDDIGAVVLFGGHEIFSAGDDMPELRT LNAPEADTAARVRLEAIDAVAAIPKPTVAAVTGYALGAGLTLALAADWRVSGDNVKFGATEILAGLIPGG GGMGRLTRVVGSSRAKELVFSGRFFDAEEALALGLIDDMVAPDDVYDSAVAWARRYLECPPRALAAAKAV INNVFELEATERAAAERRRYVELFAAGQRGPDGRGPGGGNTDDQDGR
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. ulcerans Agy99 | MUL_1899 | echA17 | - | 100% (257) | enoyl-CoA hydratase |
| M. ulcerans Agy99 | MUL_0210 | echA8 | 3e-35 | 36.97% (238) | enoyl-CoA hydratase |
| M. ulcerans Agy99 | MUL_0310 | echA8_2 | 7e-24 | 34.02% (244) | enoyl-CoA hydratase, EchA8_2 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3065c | echA17 | 1e-109 | 77.31% (260) | enoyl-CoA hydratase |
| M. gilvum PYR-GCK | Mflv_4270 | - | 2e-75 | 65.32% (222) | enoyl-CoA hydratase |
| M. tuberculosis H37Rv | Rv3039c | echA17 | 1e-109 | 77.31% (260) | enoyl-CoA hydratase |
| M. leprae Br4923 | MLBr_01724 | - | 1e-100 | 76.54% (243) | enoyl-CoA hydratase |
| M. abscessus ATCC 19977 | MAB_3382c | - | 5e-69 | 55.42% (240) | enoyl-CoA hydratase/isomerase |
| M. marinum M | MMAR_1662 | echA17 | 1e-142 | 98.83% (257) | enoyl-CoA hydratase EchA17 |
| M. avium 104 | MAV_3904 | - | 1e-107 | 76.38% (254) | enoyl-CoA hydratase |
| M. smegmatis MC2 155 | MSMEG_2328 | - | 3e-75 | 64.52% (217) | enoyl-CoA hydratase |
| M. thermoresistible (build 8) | TH_3663 | - | 1e-36 | 64.23% (123) | PUTATIVE Enoyl-CoA hydratase/isomerase |
| M. vanbaalenii PYR-1 | Mvan_2089 | - | 5e-78 | 67.92% (212) | enoyl-CoA hydratase |
CLUSTAL 2.0.9 multiple sequence alignment
MUL_1899|M.ulcerans_Agy99 ---MNEFVSVVA----------DQGLATLVVFRPPTNAMTRQVYREIVAA
MMAR_1662|M.marinum_M ---MNEFVSVVA----------DQGLATLVVSRPPTNAMTRQVYREIVAA
Mb3065c|M.bovis_AF2122/97 ---MPEFVNVVVSD-----GSQDAGLAMLLLSRPPTNAMTRQVYREVVAA
Rv3039c|M.tuberculosis_H37Rv ---MPEFVNVVVSD-----GSQDAGLAMLLLSRPPTNAMTRQVYREVVAA
MLBr_01724|M.leprae_Br4923 ---MSEFVNIVVSD-----GSQDAGLAILLLSRPPTNAMTRQFYREIAMA
MAV_3904|M.avium_104 MAALNEFVSVVVSD-----GSRDAGLAMLLVSRPPTNALSRQVYREVIAA
Mflv_4270|M.gilvum_PYR-GCK ---MREFVTVAVSGEGAVPDDGERRIATLLLSRPPTNALTRQMNREIADA
Mvan_2089|M.vanbaalenii_PYR-1 ---MREFVSSVLP-------EGGPGIATLLLSRPPTNALTRQVHREIVEA
MSMEG_2328|M.smegmatis_MC2_155 ---MNEFIKIVLGS-----APEQTGVATLLLSRPPTNALTRQMYREISIA
MAB_3382c|M.abscessus_ATCC_199 -MIEPEFVSVRTAP-------EHPGIGTIALSRPPTNTFTRQMYRELAQA
TH_3663|M.thermoresistible__bu ---MREFVSIHTGD-------EQPGVATLTWSRPPSNALTRQLYRELAAA
**:. :. : ***:*:::**. **: *
MUL_1899|M.ulcerans_Agy99 ADELGRRDDIGAVVLFGGHEIFSAGDDMPELRTLNAPEADTAARVRLEAI
MMAR_1662|M.marinum_M ADELGRRDDIGAVVLFGGHEIFSAGDDMPELRTLNAPEADTAARVRLEAI
Mb3065c|M.bovis_AF2122/97 ANELGRRDDVAAVILYGGHEIFSAGDDMPELRTLSAQEADTAARIRQQAV
Rv3039c|M.tuberculosis_H37Rv ANELGRRDDVAAVILYGGHEIFSAGDDMPELRTLSAQEADTAARIRQQAV
MLBr_01724|M.leprae_Br4923 ADELGRRDDVAAVILFGGHDIFSAGDDMQELRTLTAVEAGVAAEVRRQAV
MAV_3904|M.avium_104 ADELGRRDDVAAVILFGGHEIFSAGDDMPELRTLRGAEAETAARVRRDAI
Mflv_4270|M.gilvum_PYR-GCK VAEVGGRDDICAVIVFGGHEMFSVGADVPELKTLDADEAGTADAVAAQAV
Mvan_2089|M.vanbaalenii_PYR-1 TAELGPRDDVFAVIVYGGHEIFSAGEDMPELDTLTADEAAVAARVCAEAV
MSMEG_2328|M.smegmatis_MC2_155 ANELAQRADVSSVIVYGGHEIFCAGDDIPELRTLDAEETAAADHALQRCI
MAB_3382c|M.abscessus_ATCC_199 AAEVNARADIRVVIVYGGHEIFCAGDDLAELSELSADEMARSAGDRQAAL
TH_3663|M.thermoresistible__bu AAEVGRHDGIAAVILFGGPEIFSAGDDAAELRTLAPRRVAAADRMCRAAF
. *: : .: *:::** ::*..* * ** * . : ..
MUL_1899|M.ulcerans_Agy99 DAVAAIPKPTVAAVTGYALGAGLTLALAADWRVSGDNVKFGATEILAGLI
MMAR_1662|M.marinum_M DAVAAIPKPTVAAVTGYALGAGLTLALAADWRVSGDNVKFGATEILAGLI
Mb3065c|M.bovis_AF2122/97 DAVAAIPKPTVAAITGYALGAGLTLALAADWRVSGDNVKFGATEILAGLI
Rv3039c|M.tuberculosis_H37Rv DAVAAIPKPTVAAITGYALGAGLTLALAADWRVSGDNVKFGATEILAGLI
MLBr_01724|M.leprae_Br4923 DAVATIPKPTVAAITGYALGAGLTLALAADWRVSGDNVKFGATEILADLV
MAV_3904|M.avium_104 DAVAAIPKPTVAAITGYALGAGLTLALAADWRISGDNVKFGATEILAGLV
Mflv_4270|M.gilvum_PYR-GCK AALAALPKPTVAAITGYALGAGLTLALAADWRVSGDNVKFGATEILAGLA
Mvan_2089|M.vanbaalenii_PYR-1 EALAALPKPTVAAITGYALGAGLTLALAADWRVSGDNVKFGATEILAGRA
MSMEG_2328|M.smegmatis_MC2_155 EAVAAIPKPTVAAVTGYALGSGMNLALAADWRVSGDNAKFGATEILAGLA
MAB_3382c|M.abscessus_ATCC_199 TAVAELAKPTIAAITGYALGSGLELALTADWRIAGDNVKVGSPEILVGMI
TH_3663|M.thermoresistible__bu DALAAIPRPTVAAITGYALGSGLTLALTADWRVXXX--RDAGTASAFQIP
*:* :.:**:**:******:*: ***:****: : ...
MUL_1899|M.ulcerans_Agy99 PGGGGMGRLTRVVGSSRAKELVFSGRFFDAEEALALGLIDDMVAPDDVYD
MMAR_1662|M.marinum_M PGGGGMGRLTRVVGSSRAKELVFSGRFFDAEEALALGLIDDMVAPDDVYD
Mb3065c|M.bovis_AF2122/97 PSGDGMARLTRAAGPSRAKELVFSGRFFDAEEALALGLIDDMVAPDDVYD
Rv3039c|M.tuberculosis_H37Rv PSGDGMARLTRAAGPSRAKELVFSGRFFDAEEALALGLIDDMVAPDDVYD
MLBr_01724|M.leprae_Br4923 PDGDGLARLTRVAGVSRAKDLVFSGRFFDAAEALALGLIDDMVAPDDVYD
MAV_3904|M.avium_104 PGGDALARLTRVAGASKAKELVFSGRFFDAEEALALGLIDEMVAPDDVYD
Mflv_4270|M.gilvum_PYR-GCK PAGDGAGRLAEAVGPSRAKDLVFSGRFVDAREAHTLGLVDELVAPDGVYD
Mvan_2089|M.vanbaalenii_PYR-1 PAGGAATRLAGAIGQSKARDLVFSGRFVDAREALKLGLVDELVAPDTVYD
MSMEG_2328|M.smegmatis_MC2_155 PRGGGGVRLADAIGTSKAKELVFSGRFVGAEEALEIGLVDEMVAPDHVYE
MAB_3382c|M.abscessus_ATCC_199 PGGGGTVRLARVVGLSRAKEMVFSGRFVGADEARGAGLIDQVVAPDDVYT
TH_3663|M.thermoresistible__bu PSPASAPRVPNPGSARAANAATPVASDDDSDPASAGATSHGSATGTAVPS
* . *:. . *. . . .: * . . .: *
MUL_1899|M.ulcerans_Agy99 SAVAWARRYLECP-----PRALAAAKAVINNVFELEATERAAAERRRYVE
MMAR_1662|M.marinum_M SAVAWARRYLECP-----PRALAAAKAVINDVFELEATERAAAERRRYVE
Mb3065c|M.bovis_AF2122/97 AAAAWARRFLDGP-----PHALAAAKAGISDVYELAPAERIAAERRRYVE
Rv3039c|M.tuberculosis_H37Rv AAAAWARRFLDGP-----PHALAAAKAGISDVYELAPAERIAAERRRYVE
MLBr_01724|M.leprae_Br4923 IAAAWARRFLDGL-----PHALAAAKAGINEVFDLEPAERIAAERRRYVE
MAV_3904|M.avium_104 AAAAWARRFLDGP-----RHALAAAKAGVDAVFELPRAERLAAGQRRYVE
Mflv_4270|M.gilvum_PYR-GCK AALAWAGRFREHP-----PEVLAAAKA----AFS--APRSVAGP------
Mvan_2089|M.vanbaalenii_PYR-1 AALAWAGRFADYP-----PEVLAAAKS----SFARDMWAGVDGR------
MSMEG_2328|M.smegmatis_MC2_155 AALAWARRFSDHP-----VDVLAAAKASLNGPVNWRGPRPTDRMVDRP--
MAB_3382c|M.abscessus_ATCC_199 EAASWARRFVDGP-----PLALAAAKEAIDHGFDGPLAAGLDKERELFCQ
TH_3663|M.thermoresistible__bu VTVAHHRRGRPSPGTATHTSATVAASIRPVGVSPATATASTSGAHPRASD
: : * . .**.
MUL_1899|M.ulcerans_Agy99 LFAAGQRGPDGRGPGGGNTDDQDGR---------
MMAR_1662|M.marinum_M LFAAGQRGPDGRGPGGGNTGDQDGR---------
Mb3065c|M.bovis_AF2122/97 VFAAGQ--------GGGSKGDRGGR---------
Rv3039c|M.tuberculosis_H37Rv VFAAGQ--------GGGSKGDRGGR---------
MLBr_01724|M.leprae_Br4923 VFAAAQ--------PSLLLGGCD-----------
MAV_3904|M.avium_104 VFSAGQ--------GGDAGADPHGG---------
Mflv_4270|M.gilvum_PYR-GCK ----------------------------------
Mvan_2089|M.vanbaalenii_PYR-1 ----------------------------------
MSMEG_2328|M.smegmatis_MC2_155 ----------------------------------
MAB_3382c|M.abscessus_ATCC_199 VFATQDRADGVTAQLEIGPGTARFRGA-------
TH_3663|M.thermoresistible__bu PVRRRTGVESVRRRTGVESVRRRTMAAATQGSAP