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M. thermoresistible (build 8) TH_3663 (-)

annotation: Enoyl-CoA hydratase/isomerase
coordinates: 2497772 - 2498590
length: 273

aa seq not available

Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. thermoresistible (build 8)TH_3663--100% (273)Enoyl-CoA hydratase/isomerase
M. thermoresistible (build 8)TH_4102-3e-1340.71% (113) PUTATIVE short chain enoyl-CoA hydratase
M. thermoresistible (build 8)TH_0952echA144e-1138.39% (112) PROBABLE ENOYL-CoA HYDRATASE ECHA14 (ENOYL HYDRASE)

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb3065cechA179e-3863.41% (123) enoyl-CoA hydratase
M. gilvum PYR-GCKMflv_4270-8e-3447.98% (173) enoyl-CoA hydratase
M. tuberculosis H37RvRv3039cechA179e-3863.41% (123) enoyl-CoA hydratase
M. leprae Br4923MLBr_01724-1e-3763.20% (125) enoyl-CoA hydratase
M. abscessus ATCC 19977MAB_3382c-9e-3457.85% (121) enoyl-CoA hydratase/isomerase
M. marinum MMMAR_1662echA174e-3765.04% (123) enoyl-CoA hydratase EchA17
M. avium 104MAV_3904-8e-3864.00% (125) enoyl-CoA hydratase
M. smegmatis MC2 155MSMEG_2328-1e-3559.20% (125) enoyl-CoA hydratase
M. ulcerans Agy99MUL_1899echA171e-3664.23% (123) enoyl-CoA hydratase
M. vanbaalenii PYR-1Mvan_2089-4e-3761.79% (123) enoyl-CoA hydratase

CLUSTAL 2.0.9 multiple sequence alignment


Mb3065c|M.bovis_AF2122/97           ---MPEFVNVVVSD-----GSQDAGLAMLLLSRPPTNAMTRQVYREVVAA
Rv3039c|M.tuberculosis_H37Rv        ---MPEFVNVVVSD-----GSQDAGLAMLLLSRPPTNAMTRQVYREVVAA
MLBr_01724|M.leprae_Br4923          ---MSEFVNIVVSD-----GSQDAGLAILLLSRPPTNAMTRQFYREIAMA
MAV_3904|M.avium_104                MAALNEFVSVVVSD-----GSRDAGLAMLLVSRPPTNALSRQVYREVIAA
MMAR_1662|M.marinum_M               ---MNEFVSVVA----------DQGLATLVVSRPPTNAMTRQVYREIVAA
MUL_1899|M.ulcerans_Agy99           ---MNEFVSVVA----------DQGLATLVVFRPPTNAMTRQVYREIVAA
Mflv_4270|M.gilvum_PYR-GCK          ---MREFVTVAVSGEGAVPDDGERRIATLLLSRPPTNALTRQMNREIADA
Mvan_2089|M.vanbaalenii_PYR-1       ---MREFVSSVLP-------EGGPGIATLLLSRPPTNALTRQVHREIVEA
MSMEG_2328|M.smegmatis_MC2_155      ---MNEFIKIVLGS-----APEQTGVATLLLSRPPTNALTRQMYREISIA
MAB_3382c|M.abscessus_ATCC_199      -MIEPEFVSVRTAP-------EHPGIGTIALSRPPTNTFTRQMYRELAQA
TH_3663|M.thermoresistible__bu      ---MREFVSIHTGD-------EQPGVATLTWSRPPSNALTRQLYRELAAA
                                         **:.                :. :   ***:*:::**. **:  *

Mb3065c|M.bovis_AF2122/97           ANELGRRDDVAAVILYGGHEIFSAGDDMPELRTLSAQEADTAARIRQQAV
Rv3039c|M.tuberculosis_H37Rv        ANELGRRDDVAAVILYGGHEIFSAGDDMPELRTLSAQEADTAARIRQQAV
MLBr_01724|M.leprae_Br4923          ADELGRRDDVAAVILFGGHDIFSAGDDMQELRTLTAVEAGVAAEVRRQAV
MAV_3904|M.avium_104                ADELGRRDDVAAVILFGGHEIFSAGDDMPELRTLRGAEAETAARVRRDAI
MMAR_1662|M.marinum_M               ADELGRRDDIGAVVLFGGHEIFSAGDDMPELRTLNAPEADTAARVRLEAI
MUL_1899|M.ulcerans_Agy99           ADELGRRDDIGAVVLFGGHEIFSAGDDMPELRTLNAPEADTAARVRLEAI
Mflv_4270|M.gilvum_PYR-GCK          VAEVGGRDDICAVIVFGGHEMFSVGADVPELKTLDADEAGTADAVAAQAV
Mvan_2089|M.vanbaalenii_PYR-1       TAELGPRDDVFAVIVYGGHEIFSAGEDMPELDTLTADEAAVAARVCAEAV
MSMEG_2328|M.smegmatis_MC2_155      ANELAQRADVSSVIVYGGHEIFCAGDDIPELRTLDAEETAAADHALQRCI
MAB_3382c|M.abscessus_ATCC_199      AAEVNARADIRVVIVYGGHEIFCAGDDLAELSELSADEMARSAGDRQAAL
TH_3663|M.thermoresistible__bu      AAEVGRHDGIAAVILFGGPEIFSAGDDAAELRTLAPRRVAAADRMCRAAF
                                    . *:  : .:  *:::** ::*..* *  **  *   .   :      ..

Mb3065c|M.bovis_AF2122/97           DAVAAIPKPTVAAITGYALGAGLTLALAADWRVSGDNVKFGATEILAGLI
Rv3039c|M.tuberculosis_H37Rv        DAVAAIPKPTVAAITGYALGAGLTLALAADWRVSGDNVKFGATEILAGLI
MLBr_01724|M.leprae_Br4923          DAVATIPKPTVAAITGYALGAGLTLALAADWRVSGDNVKFGATEILADLV
MAV_3904|M.avium_104                DAVAAIPKPTVAAITGYALGAGLTLALAADWRISGDNVKFGATEILAGLV
MMAR_1662|M.marinum_M               DAVAAIPKPTVAAVTGYALGAGLTLALAADWRVSGDNVKFGATEILAGLI
MUL_1899|M.ulcerans_Agy99           DAVAAIPKPTVAAVTGYALGAGLTLALAADWRVSGDNVKFGATEILAGLI
Mflv_4270|M.gilvum_PYR-GCK          AALAALPKPTVAAITGYALGAGLTLALAADWRVSGDNVKFGATEILAGLA
Mvan_2089|M.vanbaalenii_PYR-1       EALAALPKPTVAAITGYALGAGLTLALAADWRVSGDNVKFGATEILAGRA
MSMEG_2328|M.smegmatis_MC2_155      EAVAAIPKPTVAAVTGYALGSGMNLALAADWRVSGDNAKFGATEILAGLA
MAB_3382c|M.abscessus_ATCC_199      TAVAELAKPTIAAITGYALGSGLELALTADWRIAGDNVKVGSPEILVGMI
TH_3663|M.thermoresistible__bu      DALAAIPRPTVAAITGYALGSGLTLALTADWRVXXX--RDAGTASAFQIP
                                     *:* :.:**:**:******:*: ***:****:     : ...       

Mb3065c|M.bovis_AF2122/97           PSGDGMARLTRAAGPSRAKELVFSGRFFDAEEALALGLIDDMVAPDDVYD
Rv3039c|M.tuberculosis_H37Rv        PSGDGMARLTRAAGPSRAKELVFSGRFFDAEEALALGLIDDMVAPDDVYD
MLBr_01724|M.leprae_Br4923          PDGDGLARLTRVAGVSRAKDLVFSGRFFDAAEALALGLIDDMVAPDDVYD
MAV_3904|M.avium_104                PGGDALARLTRVAGASKAKELVFSGRFFDAEEALALGLIDEMVAPDDVYD
MMAR_1662|M.marinum_M               PGGGGMGRLTRVVGSSRAKELVFSGRFFDAEEALALGLIDDMVAPDDVYD
MUL_1899|M.ulcerans_Agy99           PGGGGMGRLTRVVGSSRAKELVFSGRFFDAEEALALGLIDDMVAPDDVYD
Mflv_4270|M.gilvum_PYR-GCK          PAGDGAGRLAEAVGPSRAKDLVFSGRFVDAREAHTLGLVDELVAPDGVYD
Mvan_2089|M.vanbaalenii_PYR-1       PAGGAATRLAGAIGQSKARDLVFSGRFVDAREALKLGLVDELVAPDTVYD
MSMEG_2328|M.smegmatis_MC2_155      PRGGGGVRLADAIGTSKAKELVFSGRFVGAEEALEIGLVDEMVAPDHVYE
MAB_3382c|M.abscessus_ATCC_199      PGGGGTVRLARVVGLSRAKEMVFSGRFVGADEARGAGLIDQVVAPDDVYT
TH_3663|M.thermoresistible__bu      PSPASAPRVPNPGSARAANAATPVASDDDSDPASAGATSHGSATGTAVPS
                                    *   .  *:.   .   *.  .  .   .:  *   .  .  .:   *  

Mb3065c|M.bovis_AF2122/97           AAAAWARRFLDGP-----PHALAAAKAGISDVYELAPAERIAAERRRYVE
Rv3039c|M.tuberculosis_H37Rv        AAAAWARRFLDGP-----PHALAAAKAGISDVYELAPAERIAAERRRYVE
MLBr_01724|M.leprae_Br4923          IAAAWARRFLDGL-----PHALAAAKAGINEVFDLEPAERIAAERRRYVE
MAV_3904|M.avium_104                AAAAWARRFLDGP-----RHALAAAKAGVDAVFELPRAERLAAGQRRYVE
MMAR_1662|M.marinum_M               SAVAWARRYLECP-----PRALAAAKAVINDVFELEATERAAAERRRYVE
MUL_1899|M.ulcerans_Agy99           SAVAWARRYLECP-----PRALAAAKAVINNVFELEATERAAAERRRYVE
Mflv_4270|M.gilvum_PYR-GCK          AALAWAGRFREHP-----PEVLAAAKA----AFS--APRSVAGP------
Mvan_2089|M.vanbaalenii_PYR-1       AALAWAGRFADYP-----PEVLAAAKS----SFARDMWAGVDGR------
MSMEG_2328|M.smegmatis_MC2_155      AALAWARRFSDHP-----VDVLAAAKASLNGPVNWRGPRPTDRMVDRP--
MAB_3382c|M.abscessus_ATCC_199      EAASWARRFVDGP-----PLALAAAKEAIDHGFDGPLAAGLDKERELFCQ
TH_3663|M.thermoresistible__bu      VTVAHHRRGRPSPGTATHTSATVAASIRPVGVSPATATASTSGAHPRASD
                                     : :   *            . .**.                        

Mb3065c|M.bovis_AF2122/97           VFAAGQ--------GGGSKGDRGGR---------
Rv3039c|M.tuberculosis_H37Rv        VFAAGQ--------GGGSKGDRGGR---------
MLBr_01724|M.leprae_Br4923          VFAAAQ--------PSLLLGGCD-----------
MAV_3904|M.avium_104                VFSAGQ--------GGDAGADPHGG---------
MMAR_1662|M.marinum_M               LFAAGQRGPDGRGPGGGNTGDQDGR---------
MUL_1899|M.ulcerans_Agy99           LFAAGQRGPDGRGPGGGNTDDQDGR---------
Mflv_4270|M.gilvum_PYR-GCK          ----------------------------------
Mvan_2089|M.vanbaalenii_PYR-1       ----------------------------------
MSMEG_2328|M.smegmatis_MC2_155      ----------------------------------
MAB_3382c|M.abscessus_ATCC_199      VFATQDRADGVTAQLEIGPGTARFRGA-------
TH_3663|M.thermoresistible__bu      PVRRRTGVESVRRRTGVESVRRRTMAAATQGSAP