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IEPEFVSVRTAPEHPGIGTIALSRPPTNTFTRQMYRELAQAAAEVNARADIRVVIVYGGHEIFCAGDDLA ELSELSADEMARSAGDRQAALTAVAELAKPTIAAITGYALGSGLELALTADWRIAGDNVKVGSPEILVGM IPGGGGTVRLARVVGLSRAKEMVFSGRFVGADEARGAGLIDQVVAPDDVYTEAASWARRFVDGPPLALAA AKEAIDHGFDGPLAAGLDKERELFCQVFATQDRADGVTAQLEIGPGTARFRGA*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. abscessus ATCC 19977 | MAB_3382c | - | - | 100% (264) | enoyl-CoA hydratase/isomerase |
| M. abscessus ATCC 19977 | MAB_1185c | - | 3e-40 | 38.75% (240) | enoyl-CoA hydratase |
| M. abscessus ATCC 19977 | MAB_0903 | - | 4e-27 | 35.04% (234) | putative enoyl-CoA hydratase/isomerase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3065c | echA17 | 1e-71 | 57.74% (239) | enoyl-CoA hydratase |
| M. gilvum PYR-GCK | Mflv_4270 | - | 9e-61 | 56.42% (218) | enoyl-CoA hydratase |
| M. tuberculosis H37Rv | Rv3039c | echA17 | 1e-71 | 57.74% (239) | enoyl-CoA hydratase |
| M. leprae Br4923 | MLBr_01724 | - | 2e-68 | 55.88% (238) | enoyl-CoA hydratase |
| M. marinum M | MMAR_1662 | echA17 | 2e-69 | 55.83% (240) | enoyl-CoA hydratase EchA17 |
| M. avium 104 | MAV_3904 | - | 4e-68 | 54.10% (244) | enoyl-CoA hydratase |
| M. smegmatis MC2 155 | MSMEG_2328 | - | 1e-68 | 59.07% (215) | enoyl-CoA hydratase |
| M. thermoresistible (build 8) | TH_4102 | - | 3e-40 | 38.75% (240) | PUTATIVE short chain enoyl-CoA hydratase |
| M. ulcerans Agy99 | MUL_1899 | echA17 | 4e-69 | 55.42% (240) | enoyl-CoA hydratase |
| M. vanbaalenii PYR-1 | Mvan_2089 | - | 4e-64 | 56.00% (225) | enoyl-CoA hydratase |
CLUSTAL 2.0.9 multiple sequence alignment
Mb3065c|M.bovis_AF2122/97 ---MPEFVNVVVSD-----GSQDAGLAMLLLSRP-PTNAMTRQVYREVVA
Rv3039c|M.tuberculosis_H37Rv ---MPEFVNVVVSD-----GSQDAGLAMLLLSRP-PTNAMTRQVYREVVA
MLBr_01724|M.leprae_Br4923 ---MSEFVNIVVSD-----GSQDAGLAILLLSRP-PTNAMTRQFYREIAM
MAV_3904|M.avium_104 MAALNEFVSVVVSD-----GSRDAGLAMLLVSRP-PTNALSRQVYREVIA
MMAR_1662|M.marinum_M ---MNEFVSVVA----------DQGLATLVVSRP-PTNAMTRQVYREIVA
MUL_1899|M.ulcerans_Agy99 ---MNEFVSVVA----------DQGLATLVVFRP-PTNAMTRQVYREIVA
Mflv_4270|M.gilvum_PYR-GCK ---MREFVTVAVSGEGAVPDDGERRIATLLLSRP-PTNALTRQMNREIAD
Mvan_2089|M.vanbaalenii_PYR-1 ---MREFVSSVLP-------EGGPGIATLLLSRP-PTNALTRQVHREIVE
MSMEG_2328|M.smegmatis_MC2_155 ---MNEFIKIVLGS-----APEQTGVATLLLSRP-PTNALTRQMYREISI
MAB_3382c|M.abscessus_ATCC_199 -MIEPEFVSVRTAP-------EHPGIGTIALSRP-PTNTFTRQMYRELAQ
TH_4102|M.thermoresistible__bu -MSAKNYETILVTR--------EDRVGIITLNRPKALNALNSQVMTEVTD
:: . :. : : ** . *::. *. *:
Mb3065c|M.bovis_AF2122/97 AANELGRRDDVAAVILYGGHEIFSAGDDMPELRTLSAQEADTAARIRQQA
Rv3039c|M.tuberculosis_H37Rv AANELGRRDDVAAVILYGGHEIFSAGDDMPELRTLSAQEADTAARIRQQA
MLBr_01724|M.leprae_Br4923 AADELGRRDDVAAVILFGGHDIFSAGDDMQELRTLTAVEAGVAAEVRRQA
MAV_3904|M.avium_104 AADELGRRDDVAAVILFGGHEIFSAGDDMPELRTLRGAEAETAARVRRDA
MMAR_1662|M.marinum_M AADELGRRDDIGAVVLFGGHEIFSAGDDMPELRTLNAPEADTAARVRLEA
MUL_1899|M.ulcerans_Agy99 AADELGRRDDIGAVVLFGGHEIFSAGDDMPELRTLNAPEADTAARVRLEA
Mflv_4270|M.gilvum_PYR-GCK AVAEVGGRDDICAVIVFGGHEMFSVGADVPELKTLDADEAGTADAVAAQA
Mvan_2089|M.vanbaalenii_PYR-1 ATAELGPRDDVFAVIVYGGHEIFSAGEDMPELDTLTADEAAVAARVCAEA
MSMEG_2328|M.smegmatis_MC2_155 AANELAQRADVSSVIVYGGHEIFCAGDDIPELRTLDAEETAAADHALQRC
MAB_3382c|M.abscessus_ATCC_199 AAAEVNARADIRVVIVYGGHEIFCAGDDLAELSELSADEMARSAGDRQAA
TH_4102|M.thermoresistible__bu AAAEFDSDPGIGAIIVTGNEKAFAAGADIKEMADLEFADVFAAD--FFAP
*. *. .: ::: *... *..* *: *: * : :
Mb3065c|M.bovis_AF2122/97 VDAVAAIPKPTVAAITGYALGAGLTLALAADWRVSGDNVKFGATEILAGL
Rv3039c|M.tuberculosis_H37Rv VDAVAAIPKPTVAAITGYALGAGLTLALAADWRVSGDNVKFGATEILAGL
MLBr_01724|M.leprae_Br4923 VDAVATIPKPTVAAITGYALGAGLTLALAADWRVSGDNVKFGATEILADL
MAV_3904|M.avium_104 IDAVAAIPKPTVAAITGYALGAGLTLALAADWRISGDNVKFGATEILAGL
MMAR_1662|M.marinum_M IDAVAAIPKPTVAAVTGYALGAGLTLALAADWRVSGDNVKFGATEILAGL
MUL_1899|M.ulcerans_Agy99 IDAVAAIPKPTVAAVTGYALGAGLTLALAADWRVSGDNVKFGATEILAGL
Mflv_4270|M.gilvum_PYR-GCK VAALAALPKPTVAAITGYALGAGLTLALAADWRVSGDNVKFGATEILAGL
Mvan_2089|M.vanbaalenii_PYR-1 VEALAALPKPTVAAITGYALGAGLTLALAADWRVSGDNVKFGATEILAGR
MSMEG_2328|M.smegmatis_MC2_155 IEAVAAIPKPTVAAVTGYALGSGMNLALAADWRVSGDNAKFGATEILAGL
MAB_3382c|M.abscessus_ATCC_199 LTAVAELAKPTIAAITGYALGSGLELALTADWRIAGDNVKVGSPEILVGM
TH_4102|M.thermoresistible__bu WSKFAATRTPTIAAVAGYALGGGCELAMMCDLLIAADTAKFGQPEIKLGV
.* .**:**::*****.* **: .* ::.*..*.* .** .
Mb3065c|M.bovis_AF2122/97 IPSGDGMARLTRAAGPSRAKELVFSGRFFDAEEALALGLIDDMVAPDDVY
Rv3039c|M.tuberculosis_H37Rv IPSGDGMARLTRAAGPSRAKELVFSGRFFDAEEALALGLIDDMVAPDDVY
MLBr_01724|M.leprae_Br4923 VPDGDGLARLTRVAGVSRAKDLVFSGRFFDAAEALALGLIDDMVAPDDVY
MAV_3904|M.avium_104 VPGGDALARLTRVAGASKAKELVFSGRFFDAEEALALGLIDEMVAPDDVY
MMAR_1662|M.marinum_M IPGGGGMGRLTRVVGSSRAKELVFSGRFFDAEEALALGLIDDMVAPDDVY
MUL_1899|M.ulcerans_Agy99 IPGGGGMGRLTRVVGSSRAKELVFSGRFFDAEEALALGLIDDMVAPDDVY
Mflv_4270|M.gilvum_PYR-GCK APAGDGAGRLAEAVGPSRAKDLVFSGRFVDAREAHTLGLVDELVAPDGVY
Mvan_2089|M.vanbaalenii_PYR-1 APAGGAATRLAGAIGQSKARDLVFSGRFVDAREALKLGLVDELVAPDTVY
MSMEG_2328|M.smegmatis_MC2_155 APRGGGGVRLADAIGTSKAKELVFSGRFVGAEEALEIGLVDEMVAPDHVY
MAB_3382c|M.abscessus_ATCC_199 IPGGGGTVRLARVVGLSRAKEMVFSGRFVGADEARGAGLIDQVVAPDDVY
TH_4102|M.thermoresistible__bu LPGMGGSQRLTRAIGKAKAMDLILTGRTIDAEEAERSGLVSRVVPADKLL
* .. **: . * ::* :::::** ..* ** **:. :*..* :
Mb3065c|M.bovis_AF2122/97 DAAAAWARRFLDGPPHALAAAKAGISDVYELAPAERIAAERRRYVEVFAA
Rv3039c|M.tuberculosis_H37Rv DAAAAWARRFLDGPPHALAAAKAGISDVYELAPAERIAAERRRYVEVFAA
MLBr_01724|M.leprae_Br4923 DIAAAWARRFLDGLPHALAAAKAGINEVFDLEPAERIAAERRRYVEVFAA
MAV_3904|M.avium_104 DAAAAWARRFLDGPRHALAAAKAGVDAVFELPRAERLAAGQRRYVEVFSA
MMAR_1662|M.marinum_M DSAVAWARRYLECPPRALAAAKAVINDVFELEATERAAAERRRYVELFAA
MUL_1899|M.ulcerans_Agy99 DSAVAWARRYLECPPRALAAAKAVINNVFELEATERAAAERRRYVELFAA
Mflv_4270|M.gilvum_PYR-GCK DAALAWAGRFREHPPEVLAAAKA----AFS--APRSVAGP----------
Mvan_2089|M.vanbaalenii_PYR-1 DAALAWAGRFADYPPEVLAAAKS----SFARDMWAGVDGR----------
MSMEG_2328|M.smegmatis_MC2_155 EAALAWARRFSDHPVDVLAAAKASLNGPVNWRGPRPTDRMVDRP------
MAB_3382c|M.abscessus_ATCC_199 TEAASWARRFVDGPPLALAAAKEAIDHGFDGPLAAGLDKERELFCQVFAT
TH_4102|M.thermoresistible__bu DEAKETAATIAAMSLSAARMAKEAVNRAFETSLAEGLLFERRVFHSAFAT
* * . **
Mb3065c|M.bovis_AF2122/97 GQ--------GGGSKGDRGGR--
Rv3039c|M.tuberculosis_H37Rv GQ--------GGGSKGDRGGR--
MLBr_01724|M.leprae_Br4923 AQ--------PSLLLGGCD----
MAV_3904|M.avium_104 GQ--------GGDAGADPHGG--
MMAR_1662|M.marinum_M GQRGPDGRGPGGGNTGDQDGR--
MUL_1899|M.ulcerans_Agy99 GQRGPDGRGPGGGNTDDQDGR--
Mflv_4270|M.gilvum_PYR-GCK -----------------------
Mvan_2089|M.vanbaalenii_PYR-1 -----------------------
MSMEG_2328|M.smegmatis_MC2_155 -----------------------
MAB_3382c|M.abscessus_ATCC_199 QDRADGVTAQLEIGPGTARFRGA
TH_4102|M.thermoresistible__bu ADQSEGMAAFTEKRPPKFTHR--